locus-tag	class	description
KFB92_00015	COG2132	Multicopper oxidase
KFB92_00040	COG0189	ligase activity
KFB92_00040	COG4067	protein conserved in archaea
KFB92_00050	COG0110	maltose O-acetyltransferase activity
KFB92_00060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFB92_00060	COG0519	Catalyzes the synthesis of GMP from XMP
KFB92_00065	COG2818	Glycosylase
KFB92_00075	COG0751	glycine-tRNA ligase activity
KFB92_00080	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_00085	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KFB92_00090	COG0318	PFAM AMP-dependent synthetase and ligase
KFB92_00090	COG0204	Acyl-transferase
KFB92_00105	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFB92_00110	COG0592	DNA-directed DNA polymerase activity
KFB92_00115	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KFB92_00120	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KFB92_00125	COG0594	ribonuclease P activity
KFB92_00130	COG0706	membrane insertase activity
KFB92_00135	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KFB92_00150	COG0318	PFAM AMP-dependent synthetase and ligase
KFB92_00155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB92_00160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFB92_00180	COG1278	Cold shock
KFB92_00185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KFB92_00200	COG0546	phosphoglycolate phosphatase activity
KFB92_00205	COG1960	acyl-CoA dehydrogenase activity
KFB92_00220	COG0445	tRNA wobble uridine modification
KFB92_00225	COG0357	Ribosomal RNA small subunit methyltransferase G
KFB92_00230	COG1192	Involved in chromosome partitioning
KFB92_00235	COG1475	DNA binding
KFB92_00245	COG0356	it plays a direct role in the translocation of protons across the membrane
KFB92_00255	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KFB92_00260	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KFB92_00265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KFB92_00270	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KFB92_00275	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KFB92_00280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KFB92_00285	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KFB92_00290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFB92_00295	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFB92_00295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFB92_00300	COG1970	mechanosensitive ion channel activity
KFB92_00305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFB92_00310	COG0318	PFAM AMP-dependent synthetase and ligase
KFB92_00315	COG0683	leucine binding
KFB92_00320	COG0824	Thioesterase
KFB92_00340	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFB92_00355	COG0668	transmembrane transport
KFB92_00375	COG0210	DNA helicase
KFB92_00380	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KFB92_00385	COG1607	acyl-coa hydrolase
KFB92_00390	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KFB92_00405	COG0573	inorganic phosphate transmembrane transporter activity
KFB92_00410	COG0581	inorganic phosphate transmembrane transporter activity
KFB92_00415	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KFB92_00430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFB92_00435	COG0798	PFAM Bile acid sodium symporter
KFB92_00440	COG0431	NADPH-dependent FMN reductase
KFB92_00450	COG4681	YaeQ
KFB92_00455	COG2119	membrane
KFB92_00470	COG2900	Belongs to the SlyX family
KFB92_00485	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KFB92_00490	COG3161	chorismate lyase activity
KFB92_00495	COG1773	rubredoxin
KFB92_00500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFB92_00510	COG0534	Mate efflux family protein
KFB92_00515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KFB92_00520	COG1121	(ABC) transporter
KFB92_00535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KFB92_00540	COG0657	acetylesterase activity
KFB92_00555	COG0500	methyltransferase
KFB92_00565	COG3550	peptidyl-serine autophosphorylation
KFB92_00570	COG1396	sequence-specific DNA binding
KFB92_00575	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KFB92_00590	COG0678	peroxiredoxin activity
KFB92_00595	COG0028	Belongs to the TPP enzyme family
KFB92_00600	COG0436	Aminotransferase
KFB92_00615	COG0842	Transport permease protein
KFB92_00620	COG1131	(ABC) transporter
KFB92_00630	COG0789	Transcriptional regulator
KFB92_00650	COG0546	phosphoglycolate phosphatase activity
KFB92_00655	COG0154	amidase activity
KFB92_00660	COG5285	phytanoyl-CoA dioxygenase
KFB92_00670	COG1960	acyl-CoA dehydrogenase activity
KFB92_00685	COG1160	GTP binding
KFB92_00705	COG2111	Na H antiporter
KFB92_00705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFB92_00710	COG1006	Multisubunit Na H antiporter MnhC subunit
KFB92_00715	COG0651	ATP synthesis coupled electron transport
KFB92_00720	COG1863	multisubunit Na H antiporter MnhE subunit
KFB92_00725	COG2212	antiporter activity
KFB92_00730	COG1320	monovalent cation:proton antiporter activity
KFB92_00735	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KFB92_00785	COG0386	Belongs to the glutathione peroxidase family
KFB92_00790	COG1272	protein, Hemolysin III
KFB92_00795	COG0783	Belongs to the Dps family
KFB92_00800	COG0678	peroxiredoxin activity
KFB92_00800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KFB92_00835	COG1024	Enoyl-CoA hydratase
KFB92_00850	COG0492	ferredoxin-NADP+ reductase activity
KFB92_00855	COG0385	Bile acid
KFB92_00860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFB92_00865	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_00935	COG0174	glutamine synthetase
KFB92_00985	COG1515	deoxyribonuclease V activity
KFB92_01005	COG1024	Enoyl-CoA hydratase
KFB92_01020	COG2076	Multidrug Resistance protein
KFB92_01025	COG0745	RESPONSE REGULATOR receiver
KFB92_01030	COG5002	protein histidine kinase activity
KFB92_01045	COG0210	DNA helicase
KFB92_01060	COG1187	pseudouridine synthase activity
KFB92_01075	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_01080	COG0606	chelatase, subunit chli
KFB92_01090	COG2960	long-chain fatty acid transporting porin activity
KFB92_01095	COG0347	Belongs to the P(II) protein family
KFB92_01100	COG0004	ammonium transporteR
KFB92_01105	COG0513	Belongs to the DEAD box helicase family
KFB92_01115	COG2267	carboxylic ester hydrolase activity
KFB92_01135	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_01150	COG1166	arginine decarboxylase activity
KFB92_01160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KFB92_01165	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KFB92_01170	COG1012	belongs to the aldehyde dehydrogenase family
KFB92_01180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFB92_01200	COG2608	mercury ion transmembrane transporter activity
KFB92_01205	COG2608	mercury ion transmembrane transporter activity
KFB92_01250	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KFB92_01260	COG1047	Peptidyl-prolyl cis-trans
KFB92_01265	COG0288	reversible hydration of carbon dioxide
KFB92_01275	COG2132	Multicopper oxidase
KFB92_01295	COG3852	Histidine kinase
KFB92_01300	COG2204	response regulator
KFB92_01325	COG0347	Belongs to the P(II) protein family
KFB92_01335	COG0463	Glycosyl transferase, family 2
KFB92_01340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KFB92_01355	COG0789	Transcriptional regulator
KFB92_01365	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KFB92_01380	COG0789	Transcriptional regulator
KFB92_01430	COG3530	Putative quorum-sensing-regulated virulence factor
KFB92_01435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB92_01440	COG0577	efflux transmembrane transporter activity
KFB92_01440	COG1136	(ABC) transporter
KFB92_01450	COG0123	including yeast histone deacetylase and acetoin utilization protein
KFB92_01470	COG1595	DNA-templated transcription, initiation
KFB92_01475	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFB92_01505	COG4221	oxidoreductase activity
KFB92_01510	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KFB92_01590	COG0248	Ppx GppA phosphatase
KFB92_01600	COG4774	siderophore transport
KFB92_01610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFB92_01620	COG0488	(ABC) transporter
KFB92_01635	COG0545	Peptidyl-prolyl cis-trans isomerase
KFB92_01645	COG1346	cytolysis
KFB92_01655	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KFB92_01665	COG2918	glutathione biosynthetic process
KFB92_01670	COG2183	response to ionizing radiation
KFB92_01690	COG2814	Major facilitator Superfamily
KFB92_01700	COG0129	dihydroxy-acid dehydratase activity
KFB92_01720	COG2133	pyrroloquinoline quinone binding
KFB92_01725	COG0625	glutathione transferase activity
KFB92_01735	COG1295	ribonuclease BN
KFB92_01750	COG1252	NADH dehydrogenase
KFB92_01755	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KFB92_01760	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KFB92_01765	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KFB92_01770	COG1011	Hydrolase
KFB92_01775	COG0667	Aldo Keto reductase
KFB92_01785	COG1519	Transferase
KFB92_01790	COG1538	Outer membrane efflux protein
KFB92_01795	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KFB92_01800	COG0494	nUDIX hydrolase
KFB92_01805	COG3151	Protein conserved in bacteria
KFB92_01810	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KFB92_01815	COG3150	esterase
KFB92_01835	COG0204	Acyl-transferase
KFB92_01840	COG0202	RNA polymerase activity
KFB92_01850	COG3122	Protein conserved in bacteria
KFB92_01865	COG2366	antibiotic biosynthetic process
KFB92_01890	COG1595	DNA-templated transcription, initiation
KFB92_01915	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KFB92_01920	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFB92_01925	COG1509	lysine 2,3-aminomutase activity
KFB92_01940	COG0560	Phosphoserine phosphatase
KFB92_01940	COG3830	Belongs to the UPF0237 family
KFB92_01955	COG1024	Enoyl-CoA hydratase
KFB92_01960	COG0688	phosphatidylethanolamine metabolic process
KFB92_01970	COG1162	GTPase activity
KFB92_01975	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KFB92_01985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KFB92_01985	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KFB92_01990	COG0802	atpase or kinase
KFB92_01995	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFB92_02005	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFB92_02010	COG1923	regulation of RNA biosynthetic process
KFB92_02015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFB92_02020	COG0330	HflC and HflK could
KFB92_02025	COG0330	HflC and HflK could
KFB92_02030	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KFB92_02035	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KFB92_02060	COG0557	exoribonuclease II activity
KFB92_02065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFB92_02070	COG0360	Binds together with S18 to 16S ribosomal RNA
KFB92_02080	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KFB92_02085	COG0359	binds to the 23S rRNA
KFB92_02090	COG0305	Participates in initiation and elongation during chromosome replication
KFB92_02095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KFB92_02105	COG0569	domain protein
KFB92_02110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KFB92_02135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFB92_02140	COG2226	methyltransferase
KFB92_02155	COG0488	(ABC) transporter
KFB92_02160	COG0840	transmembrane signaling receptor activity
KFB92_02175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KFB92_02185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KFB92_02190	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFB92_02190	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFB92_02205	COG3706	GGDEF domain
KFB92_02210	COG3396	Phenylacetate-CoA oxygenase
KFB92_02215	COG3460	Phenylacetate-CoA oxygenase
KFB92_02220	COG3396	Phenylacetate-CoA oxygenase
KFB92_02225	COG2151	metal-sulfur cluster biosynthetic enzyme
KFB92_02230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KFB92_02235	COG1012	belongs to the aldehyde dehydrogenase family
KFB92_02235	COG2030	dehydratase
KFB92_02305	COG0625	glutathione transferase activity
KFB92_02320	COG2207	Transcriptional regulator
KFB92_02325	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KFB92_02330	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KFB92_02335	COG0681	Belongs to the peptidase S26 family
KFB92_02355	COG0559	Belongs to the binding-protein-dependent transport system permease family
KFB92_02365	COG3327	negative regulation of DNA-templated transcription, initiation
KFB92_02370	COG1024	Enoyl-CoA hydratase
KFB92_02375	COG2050	protein possibly involved in aromatic compounds catabolism
KFB92_02390	COG0583	DNA-binding transcription factor activity
KFB92_02430	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KFB92_02435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFB92_02440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KFB92_02445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KFB92_02450	COG0142	geranyltranstransferase activity
KFB92_02470	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_02475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFB92_02490	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFB92_02510	COG2205	protein histidine kinase activity
KFB92_02520	COG0662	Cupin 2, conserved barrel domain protein
KFB92_02525	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KFB92_02535	COG1846	Transcriptional regulator
KFB92_02540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFB92_02550	COG1469	GTP cyclohydrolase I activity
KFB92_02575	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KFB92_02585	COG0215	cysteine-tRNA ligase activity
KFB92_02590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KFB92_02600	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KFB92_02605	COG2203	Gaf domain
KFB92_02605	COG3706	GGDEF domain
KFB92_02605	COG4251	negative regulation of phosphorylation
KFB92_02605	COG5001	Diguanylate cyclase
KFB92_02625	COG0537	adenosine 5'-monophosphoramidase activity
KFB92_02640	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
KFB92_02650	COG2267	carboxylic ester hydrolase activity
KFB92_02660	COG0300	oxidoreductase activity
KFB92_02675	COG1335	isochorismatase
KFB92_02700	COG1793	dna ligase
KFB92_02700	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KFB92_02705	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KFB92_02705	COG1793	dna ligase
KFB92_02710	COG1201	RNA secondary structure unwinding
KFB92_02720	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
KFB92_02725	COG2835	tetraacyldisaccharide 4'-kinase activity
KFB92_02730	COG1960	acyl-CoA dehydrogenase activity
KFB92_02740	COG1335	isochorismatase
KFB92_02745	COG0583	DNA-binding transcription factor activity
KFB92_02755	COG1960	acyl-CoA dehydrogenase activity
KFB92_02780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KFB92_02800	COG3278	Belongs to the heme-copper respiratory oxidase family
KFB92_02835	COG2186	Transcriptional regulator
KFB92_02840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFB92_02845	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KFB92_02850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KFB92_02860	COG3189	MarR family transcriptional regulator
KFB92_02865	COG2070	2-Nitropropane dioxygenase
KFB92_02885	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFB92_02890	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFB92_02895	COG0583	DNA-binding transcription factor activity
KFB92_02905	COG2860	membrane
KFB92_02930	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KFB92_02935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KFB92_02940	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KFB92_02945	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KFB92_02960	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_02965	COG0617	tRNA 3'-terminal CCA addition
KFB92_02980	COG3842	ATPase activity
KFB92_02985	COG4149	molybdate abc transporter
KFB92_02990	COG1840	ABC-type Fe3 transport system, periplasmic component
KFB92_02995	COG2719	SpoVR family
KFB92_03000	COG2718	Belongs to the UPF0229 family
KFB92_03005	COG2766	serine protein kinase
KFB92_03010	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KFB92_03015	COG2967	ApaG domain
KFB92_03020	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KFB92_03025	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KFB92_03030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFB92_03035	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KFB92_03050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KFB92_03060	COG0791	NLP P60 protein
KFB92_03080	COG0477	Major facilitator Superfamily
KFB92_03085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KFB92_03090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFB92_03095	COG1845	cytochrome c oxidase, subunit III
KFB92_03100	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KFB92_03115	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KFB92_03125	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFB92_03130	COG0512	Glutamine amidotransferase of anthranilate synthase
KFB92_03135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFB92_03140	COG0134	indole-3-glycerol-phosphate synthase activity
KFB92_03150	COG1765	OsmC-like protein
KFB92_03155	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KFB92_03160	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KFB92_03170	COG0784	Response regulator, receiver
KFB92_03170	COG2205	protein histidine kinase activity
KFB92_03170	COG5002	protein histidine kinase activity
KFB92_03175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFB92_03180	COG0151	Belongs to the GarS family
KFB92_03185	COG0138	bifunctional purine biosynthesis protein purh
KFB92_03220	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KFB92_03235	COG2226	methyltransferase
KFB92_03255	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KFB92_03300	COG0205	6-phosphofructokinase activity
KFB92_03315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KFB92_03315	COG2205	protein histidine kinase activity
KFB92_03345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFB92_03370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFB92_03375	COG0163	prenyltransferase activity
KFB92_03395	COG0848	biopolymer transport protein
KFB92_03400	COG0811	peptide transport
KFB92_03405	COG3015	lipoprotein NlpE involved in copper resistance
KFB92_03425	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KFB92_03430	COG0321	lipoyl(octanoyl) transferase activity
KFB92_03440	COG2890	protein-(glutamine-N5) methyltransferase activity
KFB92_03455	COG1686	Belongs to the peptidase S11 family
KFB92_03460	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KFB92_03465	COG2951	lytic endotransglycosylase activity
KFB92_03470	COG0772	Belongs to the SEDS family
KFB92_03475	COG0768	penicillin binding
KFB92_03480	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KFB92_03490	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KFB92_03495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KFB92_03515	COG0495	leucyl-tRNA aminoacylation
KFB92_03525	COG0659	secondary active sulfate transmembrane transporter activity
KFB92_03545	COG4535	Mg2 and Co2 transporter CorC
KFB92_03550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KFB92_03555	COG1702	phosphate starvation-inducible protein PhoH
KFB92_03560	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KFB92_03565	COG4208	sulfate ABC transporter
KFB92_03575	COG1595	DNA-templated transcription, initiation
KFB92_03590	COG4150	thiosulfate binding
KFB92_03595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFB92_03640	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KFB92_03650	COG3047	cAMP biosynthetic process
KFB92_03695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFB92_03700	COG1278	Cold shock
KFB92_03715	COG0501	Belongs to the peptidase M48B family
KFB92_03720	COG1704	LemA family
KFB92_03725	COG0109	protoheme IX farnesyltransferase activity
KFB92_03730	COG1612	heme a metabolic process
KFB92_03755	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KFB92_03760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFB92_03765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KFB92_03790	COG1064	alcohol dehydrogenase
KFB92_03820	COG3813	Protein conserved in bacteria
KFB92_03830	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KFB92_03840	COG0346	lactoylglutathione lyase activity
KFB92_03855	COG3665	Urea carboxylase-associated protein
KFB92_03870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KFB92_03895	COG2827	Endonuclease containing a URI domain
KFB92_03915	COG2863	cytochrome
KFB92_03920	COG3258	Cytochrome c
KFB92_03935	COG1104	cysteine desulfurase activity
KFB92_03945	COG2166	iron-sulfur cluster assembly
KFB92_03955	COG0316	Belongs to the HesB IscA family
KFB92_03965	COG0719	Fe-S assembly protein
KFB92_03970	COG0396	ATPase activity
KFB92_03975	COG0719	Fe-S assembly protein
KFB92_03980	COG0105	UTP biosynthetic process
KFB92_03985	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KFB92_03995	COG1426	Protein conserved in bacteria
KFB92_04000	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KFB92_04005	COG0124	histidyl-tRNA synthetase
KFB92_04020	COG1160	GTP binding
KFB92_04035	COG0784	Response regulator, receiver
KFB92_04035	COG2205	protein histidine kinase activity
KFB92_04035	COG5002	protein histidine kinase activity
KFB92_04040	COG1570	exodeoxyribonuclease VII activity
KFB92_04050	COG0519	Catalyzes the synthesis of GMP from XMP
KFB92_04050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFB92_04070	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KFB92_04110	COG1304	FMN binding
KFB92_04150	COG2814	Major facilitator Superfamily
KFB92_04175	COG4221	oxidoreductase activity
KFB92_04190	COG3550	peptidyl-serine autophosphorylation
KFB92_04200	COG0583	DNA-binding transcription factor activity
KFB92_04250	COG4977	sequence-specific DNA binding
KFB92_04265	COG2207	Transcriptional regulator
KFB92_04270	COG5001	Diguanylate cyclase
KFB92_04270	COG2203	Gaf domain
KFB92_04270	COG3706	GGDEF domain
KFB92_04270	COG4251	negative regulation of phosphorylation
KFB92_04320	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
KFB92_04330	COG2272	Belongs to the type-B carboxylesterase lipase family
KFB92_04335	COG2272	Belongs to the type-B carboxylesterase lipase family
KFB92_04350	COG3457	Alanine racemase
KFB92_04360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KFB92_04370	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KFB92_04375	COG3541	Predicted nucleotidyltransferase
KFB92_04395	COG3938	Belongs to the proline racemase family
KFB92_04405	COG3647	Membrane
KFB92_04415	COG1307	EDD domain protein, DegV family
KFB92_04420	COG0477	Major facilitator Superfamily
KFB92_04425	COG3795	YCII-related domain
KFB92_04455	COG0583	DNA-binding transcription factor activity
KFB92_04460	COG1960	acyl-CoA dehydrogenase activity
KFB92_04465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KFB92_04510	COG1024	Enoyl-CoA hydratase
KFB92_04515	COG0183	Belongs to the thiolase family
KFB92_04545	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KFB92_04555	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KFB92_04570	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KFB92_04570	COG3323	Protein of unknown function (DUF1653)
KFB92_04575	COG2816	NAD+ diphosphatase activity
KFB92_04595	COG1752	Esterase of the alpha-beta hydrolase superfamily
KFB92_04600	COG4536	flavin adenine dinucleotide binding
KFB92_04615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KFB92_04620	COG0228	four-way junction DNA binding
KFB92_04625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KFB92_04630	COG0336	Belongs to the RNA methyltransferase TrmD family
KFB92_04635	COG0335	large ribosomal subunit rRNA binding
KFB92_04650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KFB92_04655	COG0436	Aminotransferase
KFB92_04665	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KFB92_04675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KFB92_04680	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KFB92_04695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KFB92_04700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFB92_04705	COG2264	protein methyltransferase activity
KFB92_04710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFB92_04765	COG0438	transferase activity, transferring glycosyl groups
KFB92_04785	COG4953	penicillin-binding protein 1C
KFB92_04795	COG0702	epimerase
KFB92_04820	COG0488	(ABC) transporter
KFB92_04825	COG1196	nuclear chromosome segregation
KFB92_04825	COG3264	Mechanosensitive ion channel
KFB92_04840	COG0709	Synthesizes selenophosphate from selenide and ATP
KFB92_04845	COG3639	organic phosphonate transmembrane transporter activity
KFB92_04850	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFB92_04850	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KFB92_04855	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
KFB92_04860	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KFB92_04865	COG2030	dehydratase
KFB92_04870	COG1309	transcriptional regulator
KFB92_04895	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_04900	COG0183	Belongs to the thiolase family
KFB92_04905	COG1946	Acyl-CoA thioesterase
KFB92_04940	COG1902	pentaerythritol trinitrate reductase activity
KFB92_04940	COG0446	pyridine nucleotide-disulphide oxidoreductase
KFB92_04950	COG1960	acyl-CoA dehydrogenase activity
KFB92_04990	COG0642	Histidine kinase
KFB92_05005	COG1115	amino acid carrier protein
KFB92_05030	COG0778	Nitroreductase
KFB92_05035	COG3360	Dodecin
KFB92_05040	COG0513	Belongs to the DEAD box helicase family
KFB92_05070	COG4771	TonB-dependent receptor
KFB92_05075	COG0596	Alpha beta hydrolase
KFB92_05085	COG0175	sulfate reduction
KFB92_05095	COG2197	response regulator
KFB92_05120	COG0488	(ABC) transporter
KFB92_05170	COG0210	DNA helicase
KFB92_05175	COG3668	Plasmid stabilization system
KFB92_05185	COG0183	Belongs to the thiolase family
KFB92_05190	COG1024	Enoyl-CoA hydratase
KFB92_05190	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFB92_05195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KFB92_05210	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KFB92_05220	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KFB92_05225	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFB92_05225	COG1024	Enoyl-CoA hydratase
KFB92_05230	COG2070	2-Nitropropane dioxygenase
KFB92_05235	COG0354	folic acid binding
KFB92_05275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFB92_05280	COG0481	GTPase activity
KFB92_05295	COG0571	ribonuclease III activity
KFB92_05300	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KFB92_05305	COG1381	Involved in DNA repair and RecF pathway recombination
KFB92_05310	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KFB92_05315	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KFB92_05320	COG0784	Response regulator, receiver
KFB92_05320	COG5002	protein histidine kinase activity
KFB92_05320	COG2205	protein histidine kinase activity
KFB92_05335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KFB92_05340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFB92_05345	COG3956	TIGRFAM MazG family protein
KFB92_05365	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFB92_05390	COG0563	adenylate kinase activity
KFB92_05395	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KFB92_05425	COG0511	ligase activity, forming carbon-carbon bonds
KFB92_05425	COG5016	pyruvate
KFB92_05430	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KFB92_05445	COG1999	signal sequence binding
KFB92_05450	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KFB92_05455	COG0583	DNA-binding transcription factor activity
KFB92_05465	COG2954	triphosphatase activity
KFB92_05475	COG4133	protoheme IX ABC transporter activity
KFB92_05495	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KFB92_05500	COG0189	ligase activity
KFB92_05515	COG0435	Glutathione S-transferase
KFB92_05540	COG1131	(ABC) transporter
KFB92_05545	COG0842	Transport permease protein
KFB92_05550	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KFB92_05550	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KFB92_05555	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KFB92_05565	COG0778	Nitroreductase
KFB92_05585	COG2116	formate transmembrane transporter activity
KFB92_05590	COG0530	calcium, potassium:sodium antiporter activity
KFB92_05605	COG2267	carboxylic ester hydrolase activity
KFB92_05610	COG0318	PFAM AMP-dependent synthetase and ligase
KFB92_05615	COG0683	leucine binding
KFB92_05620	COG0559	Belongs to the binding-protein-dependent transport system permease family
KFB92_05645	COG0183	Belongs to the thiolase family
KFB92_05650	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_05660	COG1960	acyl-CoA dehydrogenase activity
KFB92_05665	COG1960	acyl-CoA dehydrogenase activity
KFB92_05670	COG1309	transcriptional regulator
KFB92_05675	COG1024	Enoyl-CoA hydratase
KFB92_05695	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_05700	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_05710	COG1024	Enoyl-CoA hydratase
KFB92_05750	COG0784	Response regulator, receiver
KFB92_05750	COG2205	protein histidine kinase activity
KFB92_05760	COG4772	TonB-dependent receptor
KFB92_05775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFB92_05780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB92_05785	COG1309	transcriptional regulator
KFB92_05795	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_05810	COG0318	PFAM AMP-dependent synthetase and ligase
KFB92_05840	COG1024	Enoyl-CoA hydratase
KFB92_05840	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFB92_05845	COG1960	acyl-CoA dehydrogenase activity
KFB92_05850	COG1960	acyl-CoA dehydrogenase activity
KFB92_05855	COG2130	NADP-dependent
KFB92_05860	COG2814	Major facilitator Superfamily
KFB92_05865	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KFB92_05875	COG0235	Class ii aldolase
KFB92_05900	COG0183	Belongs to the thiolase family
KFB92_05905	COG1846	Transcriptional regulator
KFB92_05910	COG1764	response to oxidative stress
KFB92_05940	COG1739	Uncharacterized protein family UPF0029
KFB92_05960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFB92_05965	COG3206	protein involved in exopolysaccharide biosynthesis
KFB92_05965	COG0489	protein tyrosine kinase activity
KFB92_05970	COG0471	metal ion transport
KFB92_05970	COG3273	potassium ion transport
KFB92_05980	COG0529	Catalyzes the synthesis of activated sulfate
KFB92_05985	COG0438	transferase activity, transferring glycosyl groups
KFB92_05995	COG2244	polysaccharide biosynthetic process
KFB92_06005	COG1216	Glycosyl transferase, family 2
KFB92_06015	COG1088	dTDP-glucose 4,6-dehydratase activity
KFB92_06020	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KFB92_06045	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KFB92_06050	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KFB92_06060	COG1132	(ABC) transporter
KFB92_06070	COG1086	Polysaccharide biosynthesis protein
KFB92_06075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KFB92_06080	COG0656	L-ascorbic acid biosynthetic process
KFB92_06095	COG1083	cytidylyl-transferase
KFB92_06110	COG2089	acid synthase
KFB92_06120	COG1215	transferase activity, transferring glycosyl groups
KFB92_06130	COG0297	glycogen (starch) synthase activity
KFB92_06155	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KFB92_06155	COG2755	lipolytic protein G-D-S-L family
KFB92_06215	COG0318	PFAM AMP-dependent synthetase and ligase
KFB92_06220	COG4214	carbohydrate transport
KFB92_06225	COG0559	Belongs to the binding-protein-dependent transport system permease family
KFB92_06245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFB92_06250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KFB92_06265	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KFB92_06295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KFB92_06300	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFB92_06310	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KFB92_06335	COG0457	Tetratricopeptide repeat
KFB92_06345	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KFB92_06350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KFB92_06360	COG0166	Belongs to the GPI family
KFB92_06375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KFB92_06390	COG0436	Aminotransferase
KFB92_06395	COG0556	nucleotide-excision repair
KFB92_06420	COG0513	Belongs to the DEAD box helicase family
KFB92_06440	COG3115	cell septum assembly
KFB92_06445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KFB92_06470	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KFB92_06470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFB92_06485	COG5002	protein histidine kinase activity
KFB92_06485	COG0784	Response regulator, receiver
KFB92_06485	COG2205	protein histidine kinase activity
KFB92_06495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KFB92_06535	COG0318	PFAM AMP-dependent synthetase and ligase
KFB92_06545	COG1024	Enoyl-CoA hydratase
KFB92_06550	COG1960	acyl-CoA dehydrogenase activity
KFB92_06555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KFB92_06560	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_06570	COG1309	transcriptional regulator
KFB92_06595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFB92_06600	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KFB92_06610	COG0308	aminopeptidase N
KFB92_06615	COG0167	dihydroorotate dehydrogenase activity
KFB92_06620	COG3130	regulation of translation
KFB92_06625	COG0116	Belongs to the methyltransferase superfamily
KFB92_06625	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KFB92_06650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFB92_06660	COG0589	response to stress
KFB92_06675	COG1253	flavin adenine dinucleotide binding
KFB92_06690	COG1472	Belongs to the glycosyl hydrolase 3 family
KFB92_06695	COG0668	transmembrane transport
KFB92_06700	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KFB92_06710	COG2081	HI0933 family
KFB92_06730	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KFB92_06735	COG1946	Acyl-CoA thioesterase
KFB92_06745	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KFB92_06750	COG1805	sodium ion transport
KFB92_06765	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KFB92_06770	COG2871	sodium ion transport
KFB92_06775	COG1477	protein flavinylation
KFB92_06780	COG2991	Protein conserved in bacteria
KFB92_06795	COG0584	glycerophosphoryl diester phosphodiesterase
KFB92_06805	COG0438	transferase activity, transferring glycosyl groups
KFB92_06815	COG0583	DNA-binding transcription factor activity
KFB92_06895	COG3101	peptidyl-lysine hydroxylation
KFB92_06900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KFB92_06910	COG0714	Associated with various cellular activities
KFB92_06945	COG1393	Belongs to the ArsC family
KFB92_06950	COG1295	ribonuclease BN
KFB92_06950	COG1959	2 iron, 2 sulfur cluster binding
KFB92_06955	COG1254	Belongs to the acylphosphatase family
KFB92_06975	COG0657	acetylesterase activity
KFB92_06980	COG2030	dehydratase
KFB92_07000	COG1024	Enoyl-CoA hydratase
KFB92_07035	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_07040	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KFB92_07045	COG2894	cell division
KFB92_07050	COG0850	regulation of cytokinetic process
KFB92_07060	COG3118	belongs to the thioredoxin family
KFB92_07070	COG0004	ammonium transporteR
KFB92_07075	COG2326	polyphosphate kinase activity
KFB92_07090	COG1199	ATP-dependent helicase activity
KFB92_07105	COG1968	undecaprenyl-diphosphatase activity
KFB92_07110	COG0742	ribosomal rna small subunit methyltransferase
KFB92_07115	COG2937	Belongs to the GPAT DAPAT family
KFB92_07130	COG1012	belongs to the aldehyde dehydrogenase family
KFB92_07140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFB92_07145	COG2171	N-acyltransferase activity
KFB92_07150	COG1393	Belongs to the ArsC family
KFB92_07155	COG0436	Aminotransferase
KFB92_07160	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KFB92_07165	COG0024	Methionine aminopeptidase
KFB92_07170	COG0052	Belongs to the universal ribosomal protein uS2 family
KFB92_07175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KFB92_07180	COG0528	UMP kinase activity
KFB92_07185	COG0233	cytoplasmic translational termination
KFB92_07195	COG0575	Belongs to the CDS family
KFB92_07200	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KFB92_07215	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
KFB92_07220	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFB92_07225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFB92_07230	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFB92_07235	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFB92_07240	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KFB92_07245	COG0587	DNA-directed DNA polymerase activity
KFB92_07250	COG0825	malonyl-CoA metabolic process
KFB92_07255	COG0037	tRNA processing
KFB92_07260	COG0504	CTP synthase activity
KFB92_07265	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KFB92_07270	COG0148	phosphopyruvate hydratase activity
KFB92_07275	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KFB92_07280	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KFB92_07285	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KFB92_07290	COG0585	pseudouridine synthase activity
KFB92_07295	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KFB92_07330	COG3001	Fructosamine kinase
KFB92_07335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KFB92_07340	COG1597	lipid kinase activity
KFB92_07345	COG0501	Belongs to the peptidase M48B family
KFB92_07355	COG2755	lipolytic protein G-D-S-L family
KFB92_07355	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KFB92_07365	COG0436	Aminotransferase
KFB92_07375	COG0672	)-iron permease
KFB92_07380	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KFB92_07390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFB92_07415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFB92_07440	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KFB92_07455	COG1643	Atp-dependent helicase
KFB92_07470	COG3220	belongs to the UPF0276 family
KFB92_07480	COG2853	Lipoprotein
KFB92_07490	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KFB92_07495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFB92_07505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFB92_07525	COG5642	Protein of unknown function (DUF2384)
KFB92_07535	COG2084	Dehydrogenase
KFB92_07555	COG2009	succinate dehydrogenase
KFB92_07560	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KFB92_07565	COG1053	succinate dehydrogenase
KFB92_07590	COG0045	succinate-CoA ligase (ADP-forming) activity
KFB92_07595	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KFB92_07610	COG1090	epimerase
KFB92_07615	COG0326	Molecular chaperone. Has ATPase activity
KFB92_07620	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KFB92_07635	COG0708	Exodeoxyribonuclease III
KFB92_07670	COG1301	dicarboxylic acid transport
KFB92_07680	COG0004	ammonium transporteR
KFB92_07695	COG2890	protein-(glutamine-N5) methyltransferase activity
KFB92_07715	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KFB92_07720	COG0066	3-isopropylmalate dehydratase activity
KFB92_07730	COG0473	3-isopropylmalate dehydrogenase activity
KFB92_07740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KFB92_07750	COG0101	tRNA pseudouridine synthase activity
KFB92_07755	COG0135	phosphoribosylanthranilate isomerase activity
KFB92_07765	COG0159	tryptophan synthase activity
KFB92_07770	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KFB92_07775	COG0285	dihydrofolate synthase activity
KFB92_07785	COG1286	toxin biosynthetic process
KFB92_07800	COG0714	Associated with various cellular activities
KFB92_07825	COG1643	Atp-dependent helicase
KFB92_07850	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFB92_07850	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFB92_07870	COG0019	diaminopimelate decarboxylase activity
KFB92_07880	COG3228	Belongs to the MtfA family
KFB92_07885	COG0789	Transcriptional regulator
KFB92_07890	COG0484	heat shock protein binding
KFB92_07895	COG0438	transferase activity, transferring glycosyl groups
KFB92_07910	COG3119	arylsulfatase activity
KFB92_07945	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFB92_07960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFB92_07975	COG1566	PFAM secretion protein HlyD family protein
KFB92_07980	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KFB92_08000	COG0544	peptidyl-prolyl cis-trans isomerase activity
KFB92_08005	COG0740	serine-type endopeptidase activity
KFB92_08010	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KFB92_08015	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KFB92_08030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFB92_08040	COG4172	Belongs to the ABC transporter superfamily
KFB92_08045	COG4239	(ABC) transporter, permease
KFB92_08050	COG4174	ABC transporter (Permease)
KFB92_08055	COG4166	transmembrane transport
KFB92_08060	COG0741	lytic transglycosylase activity
KFB92_08060	COG1388	LysM domain
KFB92_08065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFB92_08075	COG0328	RNA-DNA hybrid ribonuclease activity
KFB92_08080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFB92_08085	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KFB92_08105	COG0616	signal peptide processing
KFB92_08110	COG0604	alcohol dehydrogenase
KFB92_08125	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFB92_08135	COG0534	Mate efflux family protein
KFB92_08140	COG0316	Belongs to the HesB IscA family
KFB92_08140	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KFB92_08145	COG0501	Belongs to the peptidase M48B family
KFB92_08165	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KFB92_08170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFB92_08245	COG0700	Nucleoside recognition
KFB92_08255	COG0598	Magnesium transport protein CorA
KFB92_08260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFB92_08270	COG3022	response to hydroperoxide
KFB92_08275	COG0589	response to stress
KFB92_08280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFB92_08300	COG2217	Heavy metal translocating P-type atpase
KFB92_08315	COG2010	Cytochrome c
KFB92_08330	COG3278	Belongs to the heme-copper respiratory oxidase family
KFB92_08340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB92_08355	COG0840	transmembrane signaling receptor activity
KFB92_08370	COG0330	HflC and HflK could
KFB92_08380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFB92_08395	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KFB92_08405	COG0180	Tryptophanyl-tRNA synthetase
KFB92_08410	COG0009	L-threonylcarbamoyladenylate synthase
KFB92_08415	COG0613	PHP domain protein
KFB92_08420	COG2917	probably involved in intracellular septation
KFB92_08425	COG2350	Protein conserved in bacteria
KFB92_08440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KFB92_08445	COG0204	Acyl-transferase
KFB92_08465	COG4181	ATPase activity
KFB92_08470	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KFB92_08475	COG2814	Major facilitator Superfamily
KFB92_08485	COG0789	Transcriptional regulator
KFB92_08490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KFB92_08500	COG2885	chlorophyll binding
KFB92_08530	COG1192	Involved in chromosome partitioning
KFB92_08545	COG0069	glutamate synthase activity
KFB92_08550	COG0741	lytic transglycosylase activity
KFB92_08565	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KFB92_08570	COG2079	MmgE PrpD family protein
KFB92_08585	COG0372	Belongs to the citrate synthase family
KFB92_08595	COG1802	Transcriptional regulator
KFB92_08605	COG0560	Phosphoserine phosphatase
KFB92_08610	COG0583	DNA-binding transcription factor activity
KFB92_08640	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KFB92_08645	COG0235	Class ii aldolase
KFB92_08650	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KFB92_08655	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KFB92_08660	COG2813	Specifically methylates the guanine in position
KFB92_08680	COG0646	methionine synthase
KFB92_08680	COG1410	methionine synthase
KFB92_08755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KFB92_08780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFB92_08785	COG0322	excinuclease ABC activity
KFB92_08795	COG1966	Carbon starvation protein
KFB92_08805	COG0003	Pfam Anion-transporting ATPase
KFB92_08825	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KFB92_08840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFB92_08845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KFB92_08845	COG1648	precorrin-2 dehydrogenase activity
KFB92_08850	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KFB92_08855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KFB92_08860	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KFB92_08865	COG1674	ftsk spoiiie
KFB92_08870	COG0492	ferredoxin-NADP+ reductase activity
KFB92_08875	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KFB92_08880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KFB92_08885	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KFB92_08890	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KFB92_08895	COG0542	response to heat
KFB92_08900	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KFB92_08905	COG1278	Cold shock
KFB92_08925	COG0482	sulfurtransferase activity
KFB92_08930	COG2915	High frequency lysogenization protein hflD homolog
KFB92_08940	COG2850	peptidyl-arginine hydroxylation
KFB92_08960	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KFB92_08980	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KFB92_08990	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KFB92_08995	COG0037	tRNA processing
KFB92_09000	COG0300	oxidoreductase activity
KFB92_09005	COG1960	acyl-CoA dehydrogenase activity
KFB92_09010	COG1960	acyl-CoA dehydrogenase activity
KFB92_09040	COG1054	Belongs to the UPF0176 family
KFB92_09045	COG0271	Belongs to the BolA IbaG family
KFB92_09065	COG0039	L-malate dehydrogenase activity
KFB92_09075	COG0617	tRNA 3'-terminal CCA addition
KFB92_09075	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KFB92_09075	COG3620	sequence-specific DNA binding
KFB92_09080	COG2943	transferase activity, transferring hexosyl groups
KFB92_09095	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KFB92_09100	COG0702	epimerase
KFB92_09115	COG1960	acyl-CoA dehydrogenase activity
KFB92_09120	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KFB92_09135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KFB92_09145	COG0824	Thioesterase
KFB92_09175	COG0587	DNA-directed DNA polymerase activity
KFB92_09205	COG3268	Saccharopine dehydrogenase
KFB92_09225	COG1368	sulfuric ester hydrolase activity
KFB92_09230	COG0579	oxidoreductase
KFB92_09255	COG0583	DNA-binding transcription factor activity
KFB92_09265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFB92_09265	COG3153	acetyltransferase
KFB92_09280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KFB92_09295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFB92_09310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFB92_09330	COG0753	catalase activity
KFB92_09340	COG0437	4 iron, 4 sulfur cluster binding
KFB92_09380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFB92_09385	COG1845	cytochrome c oxidase, subunit III
KFB92_09395	COG0069	glutamate synthase activity
KFB92_09405	COG1322	Protein conserved in bacteria
KFB92_09410	COG0084	hydrolase, TatD family'
KFB92_09425	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFB92_09430	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KFB92_09435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KFB92_09440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KFB92_09445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFB92_09460	COG0416	fatty acid biosynthetic process
KFB92_09465	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KFB92_09470	COG1399	metal-binding, possibly nucleic acid-binding protein
KFB92_09475	COG0424	maF-like protein
KFB92_09480	COG0616	signal peptide processing
KFB92_09480	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KFB92_09495	COG1530	ribonuclease E activity
KFB92_09505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB92_09515	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KFB92_09520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFB92_09525	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KFB92_09530	COG1663	tetraacyldisaccharide 4'-kinase activity
KFB92_09535	COG1132	(ABC) transporter
KFB92_09540	COG0848	biopolymer transport protein
KFB92_09545	COG0811	peptide transport
KFB92_09560	COG1136	(ABC) transporter
KFB92_09565	COG4591	ABC-type transport system involved in lipoprotein release permease component
KFB92_09580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFB92_09595	COG2223	nitrite transmembrane transporter activity
KFB92_09600	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KFB92_09605	COG0788	formyltetrahydrofolate deformylase activity
KFB92_09615	COG3046	protein related to deoxyribodipyrimidine photolyase
KFB92_09630	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KFB92_09675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFB92_09700	COG2144	transferase activity, transferring acyl groups
KFB92_09710	COG0492	ferredoxin-NADP+ reductase activity
KFB92_09715	COG1024	Enoyl-CoA hydratase
KFB92_09715	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFB92_09720	COG0183	Belongs to the thiolase family
KFB92_09735	COG2840	Smr protein MutS2
KFB92_09740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFB92_09750	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KFB92_09760	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KFB92_09765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KFB92_09780	COG0717	Belongs to the dCTP deaminase family
KFB92_09785	COG0489	protein tyrosine kinase activity
KFB92_09805	COG0450	alkyl hydroperoxide reductase
KFB92_09815	COG1793	dna ligase
KFB92_09820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KFB92_09825	COG2813	Specifically methylates the guanine in position
KFB92_09835	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KFB92_09855	COG0535	radical SAM domain protein
KFB92_09865	COG3540	Alkaline phosphatase
KFB92_09870	COG5002	protein histidine kinase activity
KFB92_09870	COG0784	Response regulator, receiver
KFB92_09870	COG2205	protein histidine kinase activity
KFB92_09875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFB92_09875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFB92_09885	COG4657	Part of a membrane complex involved in electron transport
KFB92_09890	COG2878	Part of a membrane complex involved in electron transport
KFB92_09900	COG4658	electron transport chain
KFB92_09905	COG4659	FMN binding
KFB92_09910	COG4660	Part of a membrane complex involved in electron transport
KFB92_09920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFB92_09925	COG1555	photosystem II stabilization
KFB92_09925	COG1596	polysaccharide export
KFB92_09930	COG0284	orotidine-5'-phosphate decarboxylase activity
KFB92_09935	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KFB92_09945	COG0776	regulation of translation
KFB92_09955	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KFB92_09960	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KFB92_09965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFB92_09970	COG0077	Prephenate dehydratase
KFB92_09970	COG1605	Chorismate mutase
KFB92_09975	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KFB92_09985	COG0402	S-adenosylhomocysteine deaminase activity
KFB92_09990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KFB92_09995	COG0546	phosphoglycolate phosphatase activity
KFB92_10000	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_10040	COG0318	PFAM AMP-dependent synthetase and ligase
KFB92_10070	COG2983	Belongs to the UPF0260 family
KFB92_10075	COG3100	YcgL domain-containing protein
KFB92_10080	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KFB92_10085	COG0588	phosphoglycerate mutase activity
KFB92_10090	COG5380	lipid catabolic process
KFB92_10095	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KFB92_10105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFB92_10110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB92_10140	COG1960	acyl-CoA dehydrogenase activity
KFB92_10145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KFB92_10150	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KFB92_10190	COG1695	Transcriptional regulator
KFB92_10210	COG1741	Belongs to the pirin family
KFB92_10215	COG0427	acetyl-CoA hydrolase
KFB92_10220	COG2076	Multidrug Resistance protein
KFB92_10235	COG0418	dihydroorotase activity
KFB92_10245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KFB92_10250	COG0840	transmembrane signaling receptor activity
KFB92_10270	COG3706	GGDEF domain
KFB92_10270	COG4251	negative regulation of phosphorylation
KFB92_10270	COG2203	Gaf domain
KFB92_10270	COG5001	Diguanylate cyclase
KFB92_10280	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KFB92_10290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KFB92_10300	COG2137	regulation of response to DNA damage stimulus
KFB92_10310	COG1546	Belongs to the CinA family
KFB92_10315	COG4566	intracellular signal transduction
KFB92_10350	COG3119	arylsulfatase activity
KFB92_10375	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KFB92_10380	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KFB92_10430	COG1509	lysine 2,3-aminomutase activity
KFB92_10435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFB92_10445	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KFB92_10455	COG1074	ATP-dependent DNA helicase activity
KFB92_10460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFB92_10470	COG3784	Protein of unknown function (DUF1318)
KFB92_10490	COG1960	acyl-CoA dehydrogenase activity
KFB92_10520	COG0776	regulation of translation
KFB92_10525	COG0072	phenylalanine-tRNA ligase activity
KFB92_10525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFB92_10530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KFB92_10535	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KFB92_10540	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KFB92_10545	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KFB92_10565	COG1271	oxidase subunit
KFB92_10570	COG1294	oxidase, subunit
KFB92_10580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KFB92_10585	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KFB92_10590	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KFB92_10600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFB92_10605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFB92_10615	COG0425	Belongs to the sulfur carrier protein TusA family
KFB92_10615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KFB92_10625	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KFB92_10630	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFB92_10640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFB92_10645	COG0415	Belongs to the DNA photolyase family
KFB92_10650	COG0789	Transcriptional regulator
KFB92_10660	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KFB92_10675	COG0314	molybdopterin synthase activity
KFB92_10685	COG0521	Mo-molybdopterin cofactor biosynthetic process
KFB92_10690	COG0746	molybdenum cofactor guanylyltransferase activity
KFB92_10695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KFB92_10700	COG0243	molybdopterin cofactor binding
KFB92_10710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFB92_10710	COG2146	nitrite reductase [NAD(P)H] activity
KFB92_10715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFB92_10720	COG1116	anion transmembrane transporter activity
KFB92_10725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KFB92_10730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KFB92_10730	COG1116	anion transmembrane transporter activity
KFB92_10735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KFB92_10735	COG1116	anion transmembrane transporter activity
KFB92_10740	COG3707	response regulator
KFB92_10745	COG0303	'Molybdopterin
KFB92_10755	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KFB92_10760	COG0602	queuosine metabolic process
KFB92_10770	COG2885	chlorophyll binding
KFB92_10775	COG0823	Involved in the tonB-independent uptake of proteins
KFB92_10795	COG0824	Thioesterase
KFB92_10800	COG2255	four-way junction helicase activity
KFB92_10805	COG0632	four-way junction helicase activity
KFB92_10810	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KFB92_10815	COG0217	transcriptional regulatory protein
KFB92_10820	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KFB92_10840	COG2226	methyltransferase
KFB92_10850	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KFB92_10855	COG0729	surface antigen
KFB92_10870	COG0442	prolyl-tRNA aminoacylation
KFB92_10880	COG1192	Involved in chromosome partitioning
KFB92_10885	COG1960	acyl-CoA dehydrogenase activity
KFB92_10890	COG1309	transcriptional regulator
KFB92_10905	COG0596	Alpha beta hydrolase
KFB92_10910	COG1285	pathogenesis
KFB92_10920	COG0513	Belongs to the DEAD box helicase family
KFB92_10930	COG1054	Belongs to the UPF0176 family
KFB92_10945	COG0189	ligase activity
KFB92_10950	COG4067	protein conserved in archaea
KFB92_10950	COG0189	ligase activity
KFB92_10960	COG0137	argininosuccinate synthase activity
KFB92_10965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFB92_10980	COG0450	alkyl hydroperoxide reductase
KFB92_10985	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KFB92_11000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFB92_11005	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KFB92_11020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KFB92_11025	COG2205	protein histidine kinase activity
KFB92_11030	COG0745	RESPONSE REGULATOR receiver
KFB92_11035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFB92_11035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KFB92_11040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFB92_11070	COG0737	Belongs to the 5'-nucleotidase family
KFB92_11090	COG0861	Integral membrane protein TerC family
KFB92_11120	COG0601	transmembrane transport
KFB92_11125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KFB92_11130	COG0444	Belongs to the ABC transporter superfamily
KFB92_11135	COG4608	Belongs to the ABC transporter superfamily
KFB92_11140	COG0747	negative chemotaxis
KFB92_11155	COG0655	NAD(P)H dehydrogenase (quinone) activity
KFB92_11175	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KFB92_11175	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KFB92_11205	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFB92_11220	COG3093	addiction module antidote protein HigA
KFB92_11260	COG5499	transcription regulator containing HTH domain
KFB92_11265	COG4680	protein conserved in bacteria
KFB92_11305	COG0545	Peptidyl-prolyl cis-trans isomerase
KFB92_11315	COG3657	addiction module killer protein
KFB92_11320	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFB92_11330	COG3077	Addiction module antitoxin, RelB DinJ family
KFB92_11350	COG0412	Dienelactone hydrolase
KFB92_11355	COG3077	Addiction module antitoxin, RelB DinJ family
KFB92_11360	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KFB92_11380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KFB92_11390	COG1611	Belongs to the LOG family
KFB92_11400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFB92_11405	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
KFB92_11420	COG0735	belongs to the Fur family
KFB92_11430	COG4221	oxidoreductase activity
KFB92_11455	COG0183	Belongs to the thiolase family
KFB92_11470	COG1116	anion transmembrane transporter activity
KFB92_11480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KFB92_11500	COG3237	CsbD-like
KFB92_11505	COG4251	negative regulation of phosphorylation
KFB92_11505	COG3706	GGDEF domain
KFB92_11505	COG5001	Diguanylate cyclase
KFB92_11505	COG2203	Gaf domain
KFB92_11515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB92_11525	COG0589	response to stress
KFB92_11530	COG0659	secondary active sulfate transmembrane transporter activity
KFB92_11535	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KFB92_11540	COG1191	sigma factor activity
KFB92_11560	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KFB92_11580	COG0840	transmembrane signaling receptor activity
KFB92_11585	COG2201	protein-glutamate methylesterase activity
KFB92_11590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KFB92_11595	COG0840	transmembrane signaling receptor activity
KFB92_11600	COG0835	chemotaxis
KFB92_11605	COG0643	Histidine kinase
KFB92_11605	COG2198	Histidine kinase
KFB92_11610	COG1360	Flagellar Motor Protein
KFB92_11675	COG1677	Flagellar hook-basal body complex protein FliE
KFB92_11720	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KFB92_11725	COG3190	flagellar
KFB92_11745	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KFB92_11760	COG1706	bacterial-type flagellum-dependent cell motility
KFB92_11765	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KFB92_11780	COG1749	Flagellar hook protein flgE
KFB92_11785	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KFB92_11790	COG1558	bacterial-type flagellum-dependent cell motility
KFB92_11815	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KFB92_11840	COG0459	protein refolding
KFB92_11845	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KFB92_11850	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_11855	COG3695	enzyme binding
KFB92_11865	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KFB92_11870	COG4206	TonB-dependent receptor
KFB92_11875	COG2096	Adenosyltransferase
KFB92_11890	COG2205	protein histidine kinase activity
KFB92_11895	COG0745	RESPONSE REGULATOR receiver
KFB92_11930	COG1115	amino acid carrier protein
KFB92_11950	COG3093	addiction module antidote protein HigA
KFB92_11965	COG4969	Belongs to the N-Me-Phe pilin family
KFB92_11980	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KFB92_11985	COG0237	dephospho-CoA kinase activity
KFB92_11990	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KFB92_11995	COG0494	nUDIX hydrolase
KFB92_12000	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KFB92_12005	COG0653	protein targeting
KFB92_12015	COG0739	heme binding
KFB92_12025	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KFB92_12040	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KFB92_12045	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFB92_12050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFB92_12055	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KFB92_12060	COG0772	Belongs to the SEDS family
KFB92_12065	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KFB92_12070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFB92_12075	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KFB92_12080	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KFB92_12095	COG0275	rRNA processing
KFB92_12100	COG2001	Belongs to the MraZ family
KFB92_12105	COG0426	domain, Protein
KFB92_12105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KFB92_12115	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KFB92_12125	COG0792	nuclease activity
KFB92_12140	COG2969	positive regulation of protein catabolic process
KFB92_12145	COG0625	glutathione transferase activity
KFB92_12150	COG2857	Cytochrome c1
KFB92_12155	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KFB92_12160	COG0723	plastoquinol--plastocyanin reductase activity
KFB92_12165	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KFB92_12170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KFB92_12175	COG0667	Aldo Keto reductase
KFB92_12210	COG3093	addiction module antidote protein HigA
KFB92_12220	COG1960	acyl-CoA dehydrogenase activity
KFB92_12225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KFB92_12240	COG2046	Belongs to the sulfate adenylyltransferase family
KFB92_12245	COG1597	lipid kinase activity
KFB92_12245	COG1803	Methylglyoxal synthase
KFB92_12255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFB92_12265	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KFB92_12270	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KFB92_12275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KFB92_12280	COG5007	Belongs to the BolA IbaG family
KFB92_12295	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KFB92_12310	COG1137	ATPase activity
KFB92_12315	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KFB92_12330	COG1660	Displays ATPase and GTPase activities
KFB92_12340	COG2239	Acts as a magnesium transporter
KFB92_12355	COG0312	modulator of DNA gyrase
KFB92_12360	COG3028	Belongs to the UPF0307 family
KFB92_12365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFB92_12370	COG0312	modulator of DNA gyrase
KFB92_12375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFB92_12385	COG0424	maF-like protein
KFB92_12390	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KFB92_12395	COG1792	Involved in formation and maintenance of cell shape
KFB92_12400	COG1077	Cell shape determining protein MreB Mrl
KFB92_12405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFB92_12410	COG0154	amidase activity
KFB92_12415	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFB92_12420	COG1024	Enoyl-CoA hydratase
KFB92_12430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KFB92_12435	COG2890	protein-(glutamine-N5) methyltransferase activity
KFB92_12440	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KFB92_12445	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KFB92_12455	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KFB92_12460	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KFB92_12470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFB92_12475	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KFB92_12480	COG0193	aminoacyl-tRNA hydrolase activity
KFB92_12490	COG0012	GTP binding
KFB92_12535	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KFB92_12545	COG0154	amidase activity
KFB92_12550	COG0436	Aminotransferase
KFB92_12560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFB92_12565	COG1862	Preprotein translocase
KFB92_12570	COG0343	queuine tRNA-ribosyltransferase activity
KFB92_12575	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KFB92_12585	COG1309	transcriptional regulator
KFB92_12590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFB92_12605	COG0633	Ferredoxin
KFB92_12650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFB92_12655	COG2030	dehydratase
KFB92_12665	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_12675	COG0318	PFAM AMP-dependent synthetase and ligase
KFB92_12680	COG1021	2,3-dihydroxybenzoate-AMP ligase
KFB92_12735	COG1960	acyl-CoA dehydrogenase activity
KFB92_12740	COG0318	PFAM AMP-dependent synthetase and ligase
KFB92_12770	COG0795	lipopolysaccharide-transporting ATPase activity
KFB92_12775	COG0795	lipopolysaccharide-transporting ATPase activity
KFB92_12780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFB92_12790	COG0525	valine-tRNA ligase activity
KFB92_12795	COG1309	transcriptional regulator
KFB92_12815	COG1597	lipid kinase activity
KFB92_12835	COG1183	phosphatidylcholine synthase activity
KFB92_12840	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KFB92_12860	COG0028	Belongs to the TPP enzyme family
KFB92_12875	COG1496	oxidoreductase activity
KFB92_12890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KFB92_12890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFB92_12950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KFB92_12955	COG1047	Peptidyl-prolyl cis-trans
KFB92_12965	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KFB92_12970	COG0196	riboflavin kinase activity
KFB92_12980	COG0268	Binds directly to 16S ribosomal RNA
KFB92_12985	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KFB92_12990	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KFB92_12995	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KFB92_13000	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KFB92_13005	COG0142	geranyltranstransferase activity
KFB92_13035	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_13055	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KFB92_13075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFB92_13085	COG0778	Nitroreductase
KFB92_13095	COG4221	oxidoreductase activity
KFB92_13120	COG2267	carboxylic ester hydrolase activity
KFB92_13140	COG3031	protein transport across the cell outer membrane
KFB92_13155	COG2814	Major facilitator Superfamily
KFB92_13195	COG0203	ribosomal protein L17
KFB92_13200	COG0202	RNA polymerase activity
KFB92_13205	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KFB92_13210	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KFB92_13215	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KFB92_13220	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KFB92_13230	COG0200	Binds to the 23S rRNA
KFB92_13235	COG1841	ribosomal large subunit assembly
KFB92_13240	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KFB92_13245	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KFB92_13250	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KFB92_13255	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KFB92_13260	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KFB92_13265	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KFB92_13270	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KFB92_13275	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KFB92_13280	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KFB92_13285	COG0255	Belongs to the universal ribosomal protein uL29 family
KFB92_13290	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KFB92_13295	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KFB92_13300	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KFB92_13305	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KFB92_13310	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KFB92_13315	COG0089	rRNA binding
KFB92_13320	COG0088	Forms part of the polypeptide exit tunnel
KFB92_13325	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KFB92_13330	COG0051	transcription antitermination factor activity, RNA binding
KFB92_13335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFB92_13340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFB92_13345	COG0049	tRNA binding
KFB92_13350	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KFB92_13355	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFB92_13360	COG0085	RNA polymerase activity
KFB92_13365	COG0222	ribosome binding
KFB92_13370	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KFB92_13375	COG0081	regulation of translation
KFB92_13380	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KFB92_13400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFB92_13430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KFB92_13435	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KFB92_13435	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KFB92_13440	COG1022	Amp-dependent synthetase and ligase
KFB92_13475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KFB92_13480	COG0739	heme binding
KFB92_13485	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KFB92_13495	COG0316	Belongs to the HesB IscA family
KFB92_13510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KFB92_13520	COG1981	membrane
KFB92_13525	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KFB92_13525	COG0352	thiamine-phosphate diphosphorylase activity
KFB92_13525	COG0351	phosphomethylpyrimidine kinase
KFB92_13530	COG0352	thiamine-phosphate diphosphorylase activity
KFB92_13535	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KFB92_13540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KFB92_13550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFB92_13555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFB92_13565	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KFB92_13570	COG1489	DNA binding
KFB92_13575	COG0436	Aminotransferase
KFB92_13580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KFB92_13585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFB92_13595	COG3852	Histidine kinase
KFB92_13605	COG0617	tRNA 3'-terminal CCA addition
KFB92_13615	COG1428	Deoxynucleoside kinase
KFB92_13620	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KFB92_13625	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KFB92_13630	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KFB92_13635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KFB92_13645	COG1566	PFAM secretion protein HlyD family protein
KFB92_13655	COG1185	polyribonucleotide nucleotidyltransferase activity
KFB92_13660	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KFB92_13670	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KFB92_13675	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KFB92_13680	COG2251	uridine kinase activity
KFB92_13680	COG0195	Participates in both transcription termination and antitermination
KFB92_13685	COG0779	Required for maturation of 30S ribosomal subunits
KFB92_13705	COG0149	triose-phosphate isomerase activity
KFB92_13710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFB92_13715	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KFB92_13720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFB92_13725	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KFB92_13735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFB92_13740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KFB92_13745	COG0505	Belongs to the CarA family
KFB92_13750	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KFB92_13755	COG0484	heat shock protein binding
KFB92_13760	COG0443	Heat shock 70 kDa protein
KFB92_13765	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KFB92_13770	COG1420	regulation of RNA biosynthetic process
KFB92_13775	COG0497	DNA recombination
KFB92_13785	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFB92_13790	COG2914	Belongs to the UPF0125 (RnfH) family
KFB92_13795	COG0733	neurotransmitter:sodium symporter activity
KFB92_13800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KFB92_13820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFB92_13835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFB92_13870	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KFB92_13875	COG2226	methyltransferase
KFB92_13880	COG0596	Alpha beta hydrolase
KFB92_13885	COG0156	8-amino-7-oxononanoate synthase activity
KFB92_13890	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KFB92_13900	COG1040	competence protein
KFB92_13905	COG2045	Belongs to the ComB family
KFB92_13915	COG2154	pterin-4-alpha-carbinolamine dehydratase
KFB92_13930	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KFB92_13935	COG0493	'glutamate synthase
KFB92_13940	COG0067	glutamate synthase
KFB92_13940	COG0069	glutamate synthase activity
KFB92_13940	COG0070	glutamate synthase
KFB92_13985	COG0281	malic enzyme
KFB92_13990	COG0254	rRNA binding
KFB92_13995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFB92_14000	COG0018	arginyl-trna synthetase
KFB92_14010	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KFB92_14015	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KFB92_14025	COG2226	methyltransferase
KFB92_14035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KFB92_14040	COG0140	phosphoribosyl-ATP diphosphatase activity
KFB92_14045	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KFB92_14050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KFB92_14060	COG1073	alpha beta
KFB92_14075	COG1490	D-aminoacyl-tRNA deacylase activity
KFB92_14100	COG3852	Histidine kinase
KFB92_14110	COG0174	glutamine synthetase
KFB92_14115	COG0425	Belongs to the sulfur carrier protein TusA family
KFB92_14120	COG0482	sulfurtransferase activity
KFB92_14125	COG0189	ligase activity
KFB92_14135	COG1217	gtp-binding protein TYPA
KFB92_14145	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KFB92_14150	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KFB92_14160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KFB92_14165	COG4942	peptidase
KFB92_14170	COG0793	Belongs to the peptidase S41A family
KFB92_14175	COG0385	Bile acid
KFB92_14185	COG1671	Belongs to the UPF0178 family
KFB92_14190	COG0107	imidazoleglycerol-phosphate synthase activity
KFB92_14195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KFB92_14200	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KFB92_14205	COG0131	Imidazoleglycerol-phosphate dehydratase
KFB92_14215	COG2205	protein histidine kinase activity
KFB92_14225	COG1194	a g-specific adenine glycosylase
KFB92_14230	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KFB92_14275	COG0439	Biotin carboxylase
KFB92_14315	COG1733	regulation of RNA biosynthetic process
KFB92_14350	COG1733	regulation of RNA biosynthetic process
KFB92_14400	COG0259	pyridoxamine-phosphate oxidase activity
KFB92_14415	COG3239	Fatty acid desaturase
KFB92_14420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KFB92_14450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB92_14455	COG4977	sequence-specific DNA binding
KFB92_14460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KFB92_14470	COG0473	3-isopropylmalate dehydrogenase activity
KFB92_14510	COG1960	acyl-CoA dehydrogenase activity
KFB92_14550	COG1309	transcriptional regulator
KFB92_14570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFB92_14580	COG1218	3'(2'),5'-bisphosphate nucleotidase
KFB92_14585	COG0494	nUDIX hydrolase
KFB92_14600	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KFB92_14600	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KFB92_14610	COG1560	Kdo2-lipid A biosynthetic process
KFB92_14620	COG0438	transferase activity, transferring glycosyl groups
KFB92_14630	COG1215	transferase activity, transferring glycosyl groups
KFB92_14640	COG0438	transferase activity, transferring glycosyl groups
KFB92_14645	COG0859	PFAM glycosyl transferase family 9
KFB92_14650	COG0859	PFAM glycosyl transferase family 9
KFB92_14665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFB92_14670	COG1392	Phosphate transport regulator
KFB92_14675	COG0306	phosphate transporter
KFB92_14680	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KFB92_14680	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KFB92_14685	COG0129	dihydroxy-acid dehydratase activity
KFB92_14700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KFB92_14700	COG0543	2 iron, 2 sulfur cluster binding
KFB92_14705	COG2995	paraquat-inducible protein a
KFB92_14710	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFB92_14710	COG3008	intermembrane lipid transfer
KFB92_14735	COG0181	hydroxymethylbilane synthase activity
KFB92_14745	COG3275	phosphorelay sensor kinase activity
KFB92_14750	COG0165	Argininosuccinate lyase
KFB92_14765	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KFB92_14770	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KFB92_14780	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KFB92_14835	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KFB92_14840	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KFB92_14845	COG0730	response to heat
KFB92_14855	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
KFB92_14860	COG0494	nUDIX hydrolase
KFB92_14880	COG2217	Heavy metal translocating P-type atpase
KFB92_14945	COG0730	response to heat
KFB92_14950	COG0659	secondary active sulfate transmembrane transporter activity
KFB92_14970	COG2974	May be involved in recombination
KFB92_14980	COG0318	PFAM AMP-dependent synthetase and ligase
KFB92_14990	COG3795	YCII-related domain
KFB92_14995	COG4941	Belongs to the sigma-70 factor family
KFB92_15010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KFB92_15025	COG0154	amidase activity
KFB92_15030	COG0346	lactoylglutathione lyase activity
KFB92_15035	COG0436	Aminotransferase
KFB92_15055	COG1278	Cold shock
KFB92_15065	COG0840	transmembrane signaling receptor activity
KFB92_15070	COG2031	fatty acid transporter
KFB92_15085	COG0656	L-ascorbic acid biosynthetic process
KFB92_15090	COG0628	permease
KFB92_15100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KFB92_15140	COG0625	glutathione transferase activity
KFB92_15145	COG1309	transcriptional regulator
KFB92_15150	COG0318	PFAM AMP-dependent synthetase and ligase
KFB92_15155	COG1960	acyl-CoA dehydrogenase activity
KFB92_15165	COG1028	Short-chain dehydrogenase reductase Sdr
KFB92_15175	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KFB92_15225	COG4529	Protein conserved in bacteria
KFB92_15245	COG1944	ATP diphosphatase activity
KFB92_15305	COG3712	iron ion homeostasis
KFB92_15385	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFB92_15390	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFB92_15395	COG0509	glycine decarboxylation via glycine cleavage system
KFB92_15400	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KFB92_15415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFB92_15420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFB92_15425	COG0006	proline dipeptidase activity
KFB92_15430	COG3079	Belongs to the UPF0149 family
KFB92_15450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KFB92_15460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KFB92_15465	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KFB92_15520	COG0126	phosphoglycerate kinase activity
KFB92_15525	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFB92_15530	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KFB92_15535	COG0640	Transcriptional regulator
KFB92_15540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KFB92_15550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KFB92_15555	COG1307	EDD domain protein, DegV family
KFB92_15565	COG2207	Transcriptional regulator
KFB92_15570	COG0656	L-ascorbic acid biosynthetic process
KFB92_15575	COG0583	DNA-binding transcription factor activity
KFB92_15580	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KFB92_15595	COG0534	Mate efflux family protein
KFB92_15620	COG0742	ribosomal rna small subunit methyltransferase
KFB92_15630	COG0612	Peptidase, M16
KFB92_15635	COG0552	protein localization to endoplasmic reticulum
KFB92_15640	COG2884	Cell division ATP-binding protein ftsE
KFB92_15645	COG2177	Part of the ABC transporter FtsEX involved in
KFB92_15655	COG2363	Small membrane protein
KFB92_15665	COG2022	thiamine diphosphate biosynthetic process
KFB92_15670	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KFB92_15695	COG0693	protein deglycase activity
KFB92_15700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFB92_15705	COG2813	Specifically methylates the guanine in position
KFB92_15705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFB92_15710	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KFB92_15715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFB92_15720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB92_15725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFB92_15745	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KFB92_15805	COG4964	Belongs to the GSP D family
KFB92_15825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KFB92_15830	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KFB92_15835	COG2003	Belongs to the UPF0758 family
KFB92_15840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KFB92_15845	COG0756	dUTP diphosphatase activity
KFB92_15855	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KFB92_15860	COG1309	transcriptional regulator
KFB92_15870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KFB92_15875	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KFB92_15880	COG1561	YicC-like family, N-terminal region
KFB92_15915	COG0464	growth
KFB92_15930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFB92_15930	COG3453	Protein conserved in bacteria
KFB92_15935	COG0640	Transcriptional regulator
KFB92_15940	COG1017	nitric oxide dioxygenase activity
KFB92_15940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KFB92_15945	COG1959	2 iron, 2 sulfur cluster binding
KFB92_15950	COG3608	succinylglutamate desuccinylase aspartoacylase
KFB92_15955	COG0194	GDP metabolic process
KFB92_15960	COG1758	RNA polymerase activity
KFB92_15965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFB92_15985	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KFB92_15990	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KFB92_15995	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KFB92_16005	COG0583	DNA-binding transcription factor activity
KFB92_16010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KFB92_16020	COG1917	Cupin 2, conserved barrel domain protein
KFB92_16020	COG4977	sequence-specific DNA binding
KFB92_16035	COG0583	DNA-binding transcription factor activity
KFB92_16060	COG0339	signal peptide processing
KFB92_16065	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KFB92_16075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KFB92_16080	COG0408	coproporphyrinogen oxidase activity
KFB92_16085	COG0009	L-threonylcarbamoyladenylate synthase
KFB92_16090	COG0758	DNA mediated transformation
KFB92_16095	COG1652	LysM domain
KFB92_16100	COG0242	peptide deformylase activity
KFB92_16105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFB92_16115	COG0569	domain protein
KFB92_16120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KFB92_16125	COG3618	amidohydrolase
KFB92_16135	COG3239	Fatty acid desaturase
KFB92_16190	COG1960	acyl-CoA dehydrogenase activity
KFB92_16210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFB92_16235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KFB92_16250	COG1764	response to oxidative stress
KFB92_16260	COG0435	Glutathione S-transferase
KFB92_16270	COG4771	TonB-dependent receptor
KFB92_16305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFB92_16320	COG0540	Belongs to the ATCase OTCase family
KFB92_16325	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KFB92_16330	COG3038	cytochrome b561
KFB92_16335	COG2353	YceI-like domain
KFB92_16340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KFB92_16345	COG1678	Uncharacterized ACR, COG1678
KFB92_16355	COG0189	ligase activity
KFB92_16375	COG0840	transmembrane signaling receptor activity
KFB92_16385	COG0643	Histidine kinase
KFB92_16385	COG2198	Histidine kinase
KFB92_16390	COG2201	protein-glutamate methylesterase activity
KFB92_16410	COG1047	Peptidyl-prolyl cis-trans
KFB92_16420	COG0330	HflC and HflK could
KFB92_16430	COG0154	amidase activity
KFB92_16435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KFB92_16470	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KFB92_16475	COG0405	Gamma-glutamyltransferase
KFB92_16520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KFB92_16525	COG0277	FAD linked oxidase domain protein
KFB92_16530	COG0179	Fumarylacetoacetate (FAA) hydrolase
KFB92_16575	COG0789	Transcriptional regulator