locus-tag	class	description
AS19_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AS19_00020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AS19_00040	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AS19_00050	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
AS19_00070	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
AS19_00080	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AS19_00090	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AS19_00100	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AS19_00140	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AS19_00150	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
AS19_00180	ENOG4105Y49	secretion protein, HlyD family
AS19_00200	ENOG41063TF	transcriptional regulator (AraC
AS19_00210	ENOG4105C26	Dehydrogenase
AS19_00220	ENOG4105C1G	acyl-Coa dehydrogenase
AS19_00230	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AS19_00240	ENOG4105EV8	ectoine hydroxylase
AS19_00250	ENOG41067VU	UPF0391 membrane protein
AS19_00260	ENOG4105EUB	pirin domain protein
AS19_00270	ENOG4105CHF	Glutathione S-transferase
AS19_00280	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AS19_00290	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AS19_00310	ENOG4105DHQ	Histidine kinase
AS19_00320	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AS19_00330	ENOG4107ZT5	Thiol disulfide interchange protein
AS19_00340	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
AS19_00350	ENOG4105CD3	dihydroorotase
AS19_00360	ENOG4105CXT	aspartate transcarbamylase
AS19_00370	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AS19_00380	ENOG4105DS1	cytochrome b561
AS19_00390	ENOG4108YYC	ycei family
AS19_00490	ENOG4108VPT	UPF0234 protein
AS19_00520	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AS19_00550	ENOG4105EVB	acetyltransferase
AS19_00590	ENOG4106MP8	UPF0754 membrane protein
AS19_00610	ENOG4108YZN	class I peptide chain release factor
AS19_00650	ENOG4105DDY	UPF0142 protein ycaO
AS19_00670	ENOG4105W3S	hemerythrin-like, metal-binding protein
AS19_00690	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
AS19_00700	ENOG4105CQB	FAD linked oxidase domain protein
AS19_00710	ENOG4108JQ1	Dehydrogenase
AS19_00780	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AS19_00790	ENOG4105CNM	Receptor
AS19_00810	ENOG4108Z9I	-acetyltransferase
AS19_00830	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AS19_00890	ENOG4107RGH	Aldehyde dehydrogenase
AS19_00900	ENOG4105U5Y	Transcriptional regulator
AS19_00910	ENOG4105DNZ	Alpha Beta Hydrolase
AS19_00920	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AS19_00970	ENOG4107XDR	Lactoylglutathione lyase
AS19_01000	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AS19_01010	ENOG4108VKM	cytochrome b561
AS19_01050	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AS19_01060	ENOG4105CBS	Chea signal transduction histidine kinase
AS19_01070	ENOG4105BZU	Histidine kinase
AS19_01080	ENOG4105C8Q	Methyl-accepting chemotaxis
AS19_01090	ENOG4108ZGA	chew protein
AS19_01100	ENOG4105M3Z	response regulator
AS19_01110	ENOG4108UNF	response regulator
AS19_01120	ENOG4105D7Z	glutathione synthase
AS19_01150	ENOG4108UJU	UPF0301 protein
AS19_01160	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AS19_01190	ENOG4105C4W	S-formylglutathione hydrolase
AS19_01210	ENOG4105CC0	LysR family Transcriptional regulator
AS19_01230	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AS19_01260	ENOG4105EEF	Alkane 1-monooxygenase
AS19_01280	ENOG4108VCD	Chaperone
AS19_01290	ENOG4105CW0	outer membrane usher protein
AS19_01310	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AS19_01320	ENOG4105C1A	potassium transporter peripheral membrane
AS19_01330	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AS19_01340	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AS19_01350	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AS19_01370	ENOG4105C79	DNA protecting protein DprA
AS19_01380	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AS19_01390	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AS19_01400	ENOG4105E2X	shikimate dehydrogenase
AS19_01430	ENOG4108Z0R	Transferase
AS19_01450	ENOG4105DGW	oligopeptidase A
AS19_01490	ENOG4108ZX5	transcriptional regulator
AS19_01500	ENOG4105DP0	ferredoxin-NADP reductase
AS19_01510	ENOG4105DUM	transcriptional regulator, lysR family
AS19_01520	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AS19_01530	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AS19_01580	ENOG4105VEQ	Cold shock protein
AS19_01600	ENOG4105NXV	High-affinity zinc uptake system protein
AS19_01610	ENOG4105FDK	ABC transporter
AS19_01620	ENOG4105FAV	ABC, transporter
AS19_01630	ENOG4107R73	Mate efflux family protein
AS19_01640	ENOG4108KHP	Diguanylate cyclase
AS19_01670	ENOG4107QZF	nitrite reductase NADPH large subunit
AS19_01680	ENOG4105VCQ	rubredoxin
AS19_01690	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
AS19_01700	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AS19_01710	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AS19_01720	ENOG4105BZU	Histidine kinase
AS19_01730	ENOG4105CB5	ATP-dependent DNA helicase recG
AS19_01740	ENOG4105C5Q	Transcriptional regulator
AS19_01760	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AS19_01770	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AS19_01800	ENOG4105KME	endoribonuclease L-psp
AS19_01810	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AS19_01830	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AS19_01840	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AS19_01850	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
AS19_01860	ENOG4105C01	Dihydroxy-acid dehydratase
AS19_01900	ENOG4105CEY	Amp-dependent synthetase and ligase
AS19_01910	ENOG4105CC9	acyl-Coa dehydrogenase
AS19_02000	ENOG4107RN6	Monooxygenase
AS19_02050	ENOG4108RZE	Tetr family transcriptional regulator
AS19_02060	ENOG4108ZX5	transcriptional regulator
AS19_02070	ENOG4107Z7P	Ferredoxin
AS19_02120	ENOG4105DSJ	YicC domain protein
AS19_02130	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AS19_02140	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AS19_02160	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
AS19_02170	ENOG4105CAS	nag kinase
AS19_02190	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AS19_02200	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AS19_02210	ENOG4105W5Q	DNA repair protein (RadC
AS19_02220	ENOG4105KDC	50s ribosomal protein l28
AS19_02230	ENOG4105W0E	50S ribosomal protein L33
AS19_02320	ENOG4105VK0	repeat-containing protein
AS19_02410	ENOG4105C94	Transporter
AS19_02470	ENOG4105DN9	Na H antiporter
AS19_02530	ENOG4105W1Y	Transcriptional regulator
AS19_02550	ENOG4105VRT	cytoplasmic protein
AS19_02570	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AS19_02580	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AS19_02590	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AS19_02600	ENOG4105DGU	Histone deacetylase
AS19_02620	ENOG4105CHU	acetyl-coa acetyltransferase
AS19_02630	ENOG4105C5H	ABC transporter
AS19_02670	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AS19_02680	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
AS19_02690	ENOG41067MG	lrgb family
AS19_02700	ENOG4105VAW	lrga family
AS19_02710	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AS19_02720	ENOG4105D9M	gamma-glutamylcysteine synthetase
AS19_02730	ENOG4105BZM	domain protein
AS19_02740	ENOG4105M3Z	response regulator
AS19_02750	ENOG4105BZS	acriflavin resistance protein
AS19_02760	ENOG4105CW7	secretion protein, HlyD family
AS19_02770	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AS19_02780	ENOG4105E0F	Histidine kinase
AS19_02800	ENOG4107ZYR	domain protein
AS19_02810	ENOG4105CZN	Potassium uptake protein
AS19_02820	ENOG4107S2Z	UPF0761 membrane protein
AS19_02830	ENOG4105CEP	NADH dehydrogenase
AS19_02840	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
AS19_02850	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AS19_02860	ENOG4105VEJ	Heat shock protein
AS19_02870	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
AS19_02880	ENOG4107RK2	ADP-ribose diphosphatase NudE
AS19_02890	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AS19_02920	ENOG4105CT3	Monooxygenase
AS19_02980	ENOG4107RN6	Monooxygenase
AS19_03010	ENOG4105C5H	ABC transporter
AS19_03040	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AS19_03060	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AS19_03070	ENOG4105DA5	(ABC) transporter
AS19_03080	ENOG4105E3A	(ABC) transporter
AS19_03090	ENOG4105FFC	UPF0187 protein
AS19_03100	ENOG4105EG6	Saccharopine dehydrogenase
AS19_03120	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AS19_03150	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AS19_03160	ENOG4105C8J	)-transporter
AS19_03170	ENOG4105VDB	UPF0125 protein
AS19_03180	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AS19_03200	ENOG41090R7	Ferric uptake
AS19_03210	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AS19_03230	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AS19_03240	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AS19_03250	ENOG4105CFG	Acts as a chaperone (By similarity)
AS19_03260	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AS19_03270	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AS19_03280	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AS19_03290	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AS19_03300	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AS19_03310	ENOG4105HBR	Rna-binding protein
AS19_03320	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AS19_03330	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AS19_03340	ENOG4105EEI	dihydropteroate synthase
AS19_03350	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AS19_03360	ENOG4105CP7	Triose-phosphate isomerase
AS19_03370	ENOG4107EJC	Preprotein translocase subunit SecG
AS19_03380	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AS19_03390	ENOG4105CHV	Transcription elongation factor NusA
AS19_03400	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AS19_03410	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AS19_03430	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AS19_03440	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AS19_03450	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AS19_03460	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AS19_03470	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AS19_03480	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AS19_03500	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AS19_03510	ENOG4105DJ0	Poly(A) Polymerase
AS19_03530	ENOG4105BZU	Histidine kinase
AS19_03550	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AS19_03560	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS19_03580	ENOG4105CHM	Aminotransferase
AS19_03590	ENOG4105PW4	Sugar fermentation stimulation protein homolog
AS19_03600	ENOG4105E27	serine threonine protein kinase
AS19_03630	ENOG4105BZ4	penicillin-binding protein
AS19_03650	ENOG4108Z66	YbaK ebsC protein
AS19_03660	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AS19_03670	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AS19_03680	ENOG4105DWF	phosphomethylpyrimidine kinase
AS19_03690	ENOG4108YXA	Membrane
AS19_03700	ENOG4105CMQ	Chloride channel
AS19_03710	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AS19_03740	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AS19_03760	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AS19_03780	ENOG4105DR5	peptidase
AS19_03790	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AS19_03810	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AS19_03820	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AS19_03840	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AS19_03850	ENOG4105PM1	preprotein translocase subunit SecE
AS19_03860	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AS19_03870	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AS19_03880	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AS19_03890	ENOG4108VZM	50s ribosomal protein L10
AS19_03900	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AS19_03910	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AS19_03920	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AS19_03930	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AS19_03940	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AS19_03950	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AS19_03960	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AS19_03970	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AS19_03980	ENOG4105KZJ	alginate biosynthesis protein Alg8
AS19_03990	ENOG4108UIA	Alginate biosynthesis protein Alg44
AS19_04020	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
AS19_04030	ENOG4108XTA	Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate
AS19_04050	ENOG4105JHR	Alginate biosynthesis protein AlgX
AS19_04090	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AS19_04100	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AS19_04110	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AS19_04120	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AS19_04130	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AS19_04140	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AS19_04150	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AS19_04160	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AS19_04170	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AS19_04180	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AS19_04190	ENOG41083MP	50s ribosomal protein l29
AS19_04200	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AS19_04210	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AS19_04220	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AS19_04230	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AS19_04240	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AS19_04250	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AS19_04260	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AS19_04270	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AS19_04280	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AS19_04290	ENOG4105VPB	50S ribosomal protein L30
AS19_04300	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AS19_04310	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AS19_04320	ENOG41067V7	50S ribosomal protein L36
AS19_04330	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AS19_04340	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AS19_04350	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AS19_04360	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AS19_04370	ENOG4108ZT0	50S ribosomal protein l17
AS19_04420	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AS19_04430	ENOG41086KC	Transcriptional regulator
AS19_04440	ENOG4107RDB	Major Facilitator
AS19_04450	ENOG4108UUM	single-stranded DNA-binding protein
AS19_04480	ENOG4105GVR	general secretion pathway protein D
AS19_04500	ENOG4105F8J	Adenylate Guanylate cyclase
AS19_04510	ENOG4105D74	hydrolase
AS19_04520	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AS19_04550	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AS19_04570	ENOG4105BZU	Histidine kinase
AS19_04590	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AS19_04610	ENOG4108ZX5	transcriptional regulator
AS19_04660	ENOG4105EAH	synthase
AS19_04670	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AS19_04680	ENOG4105K46	50S ribosomal protein l27
AS19_04690	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AS19_04700	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AS19_04710	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AS19_04720	ENOG4105CJR	Integral membrane protein (MviN
AS19_04730	ENOG4105DTN	riboflavin biosynthesis protein ribF
AS19_04740	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AS19_04750	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AS19_04760	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AS19_04770	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AS19_04850	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AS19_04860	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AS19_04870	ENOG4107TUY	Histidine kinase
AS19_04900	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS19_04910	ENOG4105C34	Pseudouridine synthase
AS19_04920	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AS19_04930	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AS19_04950	ENOG4105C7K	acetolactate synthase
AS19_04960	ENOG4108ZP8	Acetolactate synthase small subunit
AS19_04990	ENOG4105EMY	transcriptional regulator
AS19_05000	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AS19_05010	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AS19_05030	ENOG4107TE5	Lipid kinase
AS19_05070	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AS19_05090	ENOG4105MYG	DNA polymerase iii, chi subunit
AS19_05100	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AS19_05110	ENOG4108M8S	permease YjgP YjgQ family protein
AS19_05120	ENOG4108K5H	permease YjgP YjgQ family protein
AS19_05140	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AS19_05150	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AS19_05160	ENOG4105VIE	preprotein translocase, subunit YajC
AS19_05170	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AS19_05180	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AS19_05200	ENOG4105CHM	Aminotransferase
AS19_05210	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AS19_05230	ENOG4108JPW	Aminotransferase
AS19_05240	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AS19_05250	ENOG4105C26	Dehydrogenase
AS19_05260	ENOG4105ECY	inositol monophosphatase
AS19_05270	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
AS19_05290	ENOG4105C3G	gtp-binding protein
AS19_05300	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AS19_05310	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AS19_05320	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AS19_05330	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AS19_05340	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
AS19_05350	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
AS19_05370	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AS19_05380	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AS19_05390	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AS19_05400	ENOG4105D06	uba thif-type nad fad binding protein
AS19_05430	ENOG4106YT9	Enoyl-CoA hydratase
AS19_05440	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AS19_05450	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AS19_05460	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AS19_05470	ENOG4105DFF	Rod shape-determining protein mreb
AS19_05480	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AS19_05490	ENOG4105VQ7	Rod shape-determining protein MreD
AS19_05500	ENOG4108Z03	MAF-like protein
AS19_05530	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AS19_05560	ENOG4105N42	UPF0307 protein
AS19_05570	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AS19_05580	ENOG4105CJW	magnesium transporter
AS19_05600	ENOG4105D0D	Nitrate reductase 2, gamma subunit
AS19_05610	ENOG4105R3A	Nitrate reductase
AS19_05620	ENOG4108IUE	nitrate reductase beta subunit
AS19_05630	ENOG4105CRU	nitrate reductase, alpha subunit
AS19_05640	ENOG4105DQQ	Major facilitator superfamily MFS_1
AS19_05650	ENOG41080Z8	PHOSPHOCARRIER protein
AS19_05660	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AS19_05670	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AS19_05680	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AS19_05690	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AS19_05700	ENOG4108IUZ	ABC transporter
AS19_05730	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AS19_05740	ENOG4105C2X	Arabinose 5-phosphate isomerase
AS19_05770	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AS19_05780	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AS19_05790	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AS19_05800	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AS19_05820	ENOG4105C0H	protease
AS19_05830	ENOG4107QNR	UPF0135 protein
AS19_05840	ENOG4105CBD	Diacylglycerol kinase
AS19_05850	ENOG4107RIQ	Sulfate adenylate transferase
AS19_05870	ENOG4105DHZ	alpha beta
AS19_05880	ENOG4105D6Z	AFG1 family ATPase
AS19_05890	ENOG4105C1G	acyl-Coa dehydrogenase
AS19_05920	ENOG4105CPC	Aldo Keto reductase
AS19_05930	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AS19_05940	ENOG4108UJD	30S ribosomal protein S9
AS19_05950	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AS19_05960	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AS19_05970	ENOG4105EIX	cytochrome c1
AS19_05980	ENOG4107MKT	Stringent starvation protein a
AS19_05990	ENOG4105KB2	stringent starvation protein b
AS19_06000	ENOG4105W4M	Transport-associated protein
AS19_06020	ENOG41082RQ	UPF0102 protein
AS19_06030	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
AS19_06040	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AS19_06060	ENOG4108V6E	Cell division protein mraZ
AS19_06070	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AS19_06090	ENOG4105CJN	penicillin-binding protein
AS19_06100	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AS19_06110	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AS19_06120	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AS19_06130	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AS19_06140	ENOG4105CNI	cell division protein FtsW
AS19_06150	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AS19_06160	ENOG4105DFU	Cell wall formation (By similarity)
AS19_06170	ENOG4105CPF	Cell wall formation (By similarity)
AS19_06180	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AS19_06190	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AS19_06200	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AS19_06210	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AS19_06230	ENOG4105DR5	peptidase
AS19_06240	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AS19_06250	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AS19_06260	ENOG4105M6F	mutator MutT protein
AS19_06270	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
AS19_06280	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AS19_06310	ENOG4107QHF	type ii secretion system protein e
AS19_06320	ENOG4105KHS	type IV fimbrial pilin protein
AS19_06340	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AS19_06350	ENOG4105BZG	amino acid carrier protein
AS19_06390	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AS19_06400	ENOG4107QSN	dihydrolipoamide acetyltransferase
AS19_06420	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AS19_06430	ENOG4105EB3	Histidine kinase
AS19_06440	ENOG4108WBT	adenosyltransferase
AS19_06450	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AS19_06460	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AS19_06500	ENOG4105CHR	reductase
AS19_06510	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AS19_06520	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AS19_06550	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AS19_06600	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AS19_06610	ENOG4105MSB	protein, conserved in bacteria
AS19_06640	ENOG4107RX2	synthase
AS19_06650	ENOG4105CHU	acetyl-coa acetyltransferase
AS19_06660	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AS19_06710	ENOG41067HS	methyltransferase
AS19_06720	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
AS19_06740	ENOG4105EWT	decarboxylase family
AS19_06760	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AS19_06770	ENOG4107SCK	Monooxygenase
AS19_06780	ENOG4105DHI	Methyltransferase
AS19_06790	ENOG4105KVH	Transcriptional regulator
AS19_06800	ENOG4105CHR	reductase
AS19_06880	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
AS19_06930	ENOG4108IG5	Transcriptional regulator
AS19_06940	ENOG4105DEN	Luciferase family
AS19_06960	ENOG4105EXC	Acyl-transferase
AS19_06990	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AS19_07030	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AS19_07050	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
AS19_07090	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AS19_07130	ENOG4107QM5	aconitate hydratase
AS19_07140	ENOG4108VKG	metal-dependent hydrolase
AS19_07240	ENOG4105C7K	acetolactate synthase
AS19_07280	ENOG4105D3R	alkyl hydroperoxide reductase
AS19_07310	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AS19_07320	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AS19_07330	ENOG4107EXC	regulatoR
AS19_07340	ENOG4105JJR	Histidine kinase
AS19_07350	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AS19_07360	ENOG4105BZU	Histidine kinase
AS19_07370	ENOG4105BZU	Histidine kinase
AS19_07380	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AS19_07390	ENOG4105DBV	ornithine carbamoyltransferase
AS19_07400	ENOG4105C8Y	Acetylornithine aminotransferase
AS19_07430	ENOG4105M2J	Glutaredoxin
AS19_07440	ENOG4105D3R	alkyl hydroperoxide reductase
AS19_07450	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AS19_07460	ENOG4105CDH	Citrulline--aspartate ligase
AS19_07490	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AS19_07500	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AS19_07520	ENOG4107RIQ	Sulfate adenylate transferase
AS19_07570	ENOG4105C1J	atp-dependent rna helicase
AS19_07580	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AS19_07600	ENOG4107QJE	Chromosome Partitioning Protein
AS19_07620	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AS19_07650	ENOG4105CFU	surface antigen
AS19_07660	ENOG4108UYB	regulatoR
AS19_07680	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AS19_07730	ENOG4105C9M	aspartyl-trna synthetase
AS19_07750	ENOG4105CDY	transcriptional regulatory protein
AS19_07760	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AS19_07770	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AS19_07780	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AS19_07790	ENOG4107YD3	Thioesterase
AS19_07800	ENOG4105E02	MotA TolQ exbB proton channel
AS19_07810	ENOG4105M8F	Biopolymer transport protein exbD tolR
AS19_07830	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AS19_07840	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AS19_07860	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AS19_07870	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AS19_07910	ENOG4105W1Y	Transcriptional regulator
AS19_07930	ENOG4107RCM	Releases the N-terminal proline from various substrates (By similarity)
AS19_07990	ENOG4108NSC	Pfam:DUF88
AS19_08050	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AS19_08070	ENOG4105CMM	transposase
AS19_08120	ENOG4108XDN	Transcriptional regulator
AS19_08130	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AS19_08160	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AS19_08170	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AS19_08180	ENOG4105ERG	peptidase m48, ste24p
AS19_08190	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AS19_08210	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS19_08220	ENOG4105RH4	Glycine cleavage system transcriptional repressor
AS19_08230	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AS19_08250	ENOG4105Q2H	domain protein
AS19_08260	ENOG4105C8V	SAICAR synthetase
AS19_08310	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AS19_08320	ENOG4108ETH	Formylglycinamide ribotide synthetase
AS19_08340	ENOG4105EGD	dinuclear metal center protein, YbgI family
AS19_08350	ENOG4105E09	nadh pyrophosphatase
AS19_08360	ENOG4106S2D	Transcriptional regulator
AS19_08380	ENOG4105P8F	nudix hydrolase
AS19_08390	ENOG4108Z0R	Transferase
AS19_08410	ENOG4105D78	K07001 NTE family protein
AS19_08420	ENOG4108JU6	CBS domain protein
AS19_08440	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AS19_08450	ENOG4105K5M	30s ribosomal protein S16
AS19_08460	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AS19_08470	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AS19_08480	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AS19_08490	ENOG4105Y3U	Transglycosylase-associated protein
AS19_08500	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AS19_08510	ENOG4105T95	Thiol disulfide interChange protein
AS19_08520	ENOG4105CHM	Aminotransferase
AS19_08530	ENOG4105D6E	homoserine dehydrogenase
AS19_08550	ENOG4105C94	Transporter
AS19_08600	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AS19_08610	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
AS19_08630	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AS19_08640	ENOG4105C0H	protease
AS19_08690	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AS19_08700	ENOG4108Z6B	deaminase
AS19_08710	ENOG4105CDV	Ompa motb domain protein
AS19_08720	ENOG4108K0B	C-di-gmp phosphodiesterase
AS19_08780	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AS19_08830	ENOG4105CSU	acyl-Coa dehydrogenase
AS19_08850	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AS19_08860	ENOG4105DA4	cytochrome c-type biogenesis protein
AS19_08870	ENOG4107QX9	Thiol disulfide interChange protein
AS19_08880	ENOG4105KWW	Biogenesis protein
AS19_08900	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AS19_08930	ENOG4108UQY	Iron-storage protein
AS19_08950	ENOG4107QSA	Oxaloacetate decarboxylase
AS19_08960	ENOG4105D9Q	decarboxylase (Beta subunit)
AS19_09010	ENOG4105CBP	Major Facilitator
AS19_09040	ENOG4105D7T	ABC transporter
AS19_09060	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AS19_09120	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AS19_09130	ENOG4105DZ2	Transcriptional regulator
AS19_09140	ENOG4108W15	Protein of unknown function (DUF1456)
AS19_09170	ENOG41080ZE	Adenylate cyclase
AS19_09200	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AS19_09210	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AS19_09220	ENOG41060IM	Heme exporter protein
AS19_09230	ENOG41067VX	Heme exporter protein
AS19_09240	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AS19_09250	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AS19_09280	ENOG4105DA5	(ABC) transporter
AS19_09290	ENOG4105E3A	(ABC) transporter
AS19_09300	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AS19_09310	ENOG4105CFC	Transporter
AS19_09450	ENOG41069NU	Nitroreductase
AS19_09460	ENOG4105F8J	Adenylate Guanylate cyclase
AS19_09560	ENOG4108I69	Glycosyl transferases group 1
AS19_09580	ENOG4105DN3	alpha-2-macroglobulin domain protein
AS19_09590	ENOG4108UK5	Transposase
AS19_09600	ENOG4108JQB	penicillin-binding protein 1C
AS19_09610	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AS19_09640	ENOG4108MRJ	
AS19_09650	ENOG4105DAY	polysaccharide export protein
AS19_09660	ENOG4105KJF	protein tyrosine phosphatase
AS19_09670	ENOG4105D75	Capsular exopolysaccharide family
AS19_09680	ENOG4107QQG	Dehydrogenase
AS19_09700	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AS19_09710	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AS19_09730	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AS19_09780	ENOG4105CPK	Glycosyl transferase (Group 1
AS19_09800	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
AS19_09820	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AS19_09840	ENOG4105CGN	Glycosyl transferase (Group 1
AS19_09850	ENOG4105D3Q	Sugar transferase
AS19_09880	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AS19_09920	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
AS19_09930	ENOG4105CY0	Metallo-Beta-Lactamase
AS19_09960	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AS19_09970	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AS19_09980	ENOG4107QP8	phosphohexose isomerase
AS19_10000	ENOG4105CMR	udp-glucose 4-epimerase
AS19_10070	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AS19_10080	ENOG4105EXN	Sulfate transport protein CysZ
AS19_10100	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AS19_10110	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AS19_10150	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AS19_10160	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
AS19_10190	ENOG4105C1G	acyl-Coa dehydrogenase
AS19_10210	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AS19_10220	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AS19_10260	ENOG4105BZS	acriflavin resistance protein
AS19_10270	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AS19_10280	ENOG4108IG5	Transcriptional regulator
AS19_10290	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AS19_10300	ENOG4105YP7	UPF0270 protein
AS19_10310	ENOG4105WJG	Glutathione
AS19_10320	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AS19_10340	ENOG4105BZU	Histidine kinase
AS19_10360	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AS19_10370	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
AS19_10460	ENOG4105CHU	acetyl-coa acetyltransferase
AS19_10470	ENOG4105C1G	acyl-Coa dehydrogenase
AS19_10510	ENOG4105C1G	acyl-Coa dehydrogenase
AS19_10520	ENOG4107QX3	carboxylase
AS19_10530	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AS19_10550	ENOG4108RZE	Tetr family transcriptional regulator
AS19_10590	ENOG4105EYW	Ion transport protein
AS19_10600	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AS19_10620	ENOG4108M0H	Extracellular lipase
AS19_10630	ENOG4105CD8	aminopeptidase N
AS19_10650	ENOG4105D25	secreted protein
AS19_10690	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
AS19_10700	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AS19_10720	ENOG4105F8V	Hydrolase, tatD family
AS19_10740	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AS19_10760	ENOG41081QV	Universal stress protein
AS19_10770	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AS19_10820	ENOG4108PXI	ErfK YbiS YcfS YnhG
AS19_10830	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AS19_10840	ENOG4105D64	Mechanosensitive ion channel
AS19_10850	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AS19_10860	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AS19_10880	ENOG4105C6T	cysteine synthase
AS19_10890	ENOG4105CBX	hi0933 family
AS19_10930	ENOG4108JA2	transcriptioN-repair coupling factor
AS19_10940	ENOG4105C29	acyl-CoA thioesterase
AS19_10950	ENOG4108RG0	uracil-dna glycosylase
AS19_10980	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AS19_10990	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AS19_11000	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AS19_11020	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AS19_11030	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
AS19_11040	ENOG4105CJ2	(LipO)protein
AS19_11080	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AS19_11100	ENOG4108MJN	Glycosyl Transferase
AS19_11130	ENOG4105DWY	Agmatine deiminase
AS19_11150	ENOG4105D60	lipoprotein releasing system transmembrane protein
AS19_11160	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AS19_11180	ENOG4108EC8	DNA internalization-related competence protein ComEC
AS19_11200	ENOG4109015	Biopolymer transport protein exbD tolR
AS19_11210	ENOG4105BZ1	(ABC) transporter
AS19_11220	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AS19_11230	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AS19_11250	ENOG4105D4A	Cell wall formation (By similarity)
AS19_11260	ENOG4105C03	ribonuclease
AS19_11270	ENOG4105EI2	Pseudouridine synthase
AS19_11280	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AS19_11290	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AS19_11300	ENOG4108UHJ	MAF-like protein
AS19_11310	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AS19_11320	ENOG4105VGS	50s ribosomal protein l32
AS19_11330	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AS19_11340	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AS19_11350	ENOG4105CHR	reductase
AS19_11360	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AS19_11370	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AS19_11390	ENOG4105HHA	aminodeoxychorismate lyase
AS19_11400	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AS19_11410	ENOG4107QRG	dna polymerase iii
AS19_11430	ENOG4105F8V	Hydrolase, tatD family
AS19_11440	ENOG4105CGY	Dna recombination protein
AS19_11470	ENOG4105C3J	Cysteine desulfurase
AS19_11500	ENOG4105D9P	serine threonine protein kinase
AS19_11510	ENOG4107R3J	Transporter
AS19_11520	ENOG4107QZF	nitrite reductase NADPH large subunit
AS19_11530	ENOG4107QZF	nitrite reductase NADPH large subunit
AS19_11540	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AS19_11570	ENOG4105EYW	Ion transport protein
AS19_11580	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AS19_11590	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AS19_11610	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AS19_11630	ENOG4107RN6	Monooxygenase
AS19_11640	ENOG4105I08	Pseudouridine synthase
AS19_11670	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AS19_11680	ENOG4105BZJ	Electron transfer flavoprotein
AS19_11690	ENOG4105C10	Electron transfer flavoprotein
AS19_11700	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
AS19_11770	ENOG4105DIJ	Phosphoethanolamine transferase
AS19_11850	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AS19_11860	ENOG4107QMS	site-determining protein
AS19_11870	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AS19_11880	ENOG4107QPN	acyl-Coa dehydrogenase
AS19_11890	ENOG4105K63	Thioredoxin
AS19_11900	ENOG4108YZA	Nitrogen regulatory protein pii
AS19_11910	ENOG4105BZU	Histidine kinase
AS19_11930	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AS19_11940	ENOG4105DVT	helicase
AS19_11950	ENOG41072GX	Peptidase M22 Glycoprotease
AS19_11970	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AS19_11980	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
AS19_11990	ENOG4105E55	glycerol-3-phosphate acyltransferase
AS19_12040	ENOG4105Y49	secretion protein, HlyD family
AS19_12060	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AS19_12080	ENOG4105KUZ	arsenate reductase
AS19_12090	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AS19_12100	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AS19_12110	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AS19_12120	ENOG4105CE9	30S ribosomal protein S2
AS19_12130	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AS19_12140	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AS19_12150	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AS19_12160	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AS19_12170	ENOG4105KNE	Phosphatidate cytidylyltransferase
AS19_12180	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AS19_12190	ENOG4105DZP	Membrane-associated zinc metalloprotease
AS19_12220	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AS19_12230	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AS19_12240	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AS19_12250	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AS19_12260	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AS19_12270	ENOG4105C0B	DNA polymerase III (alpha subunit)
AS19_12280	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AS19_12290	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AS19_12300	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AS19_12310	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AS19_12320	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AS19_12330	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AS19_12340	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AS19_12360	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AS19_12370	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AS19_12380	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AS19_12400	ENOG4108K5P	(LipO)protein
AS19_12410	ENOG41076HS	cation diffusion facilitator family transporter
AS19_12440	ENOG4105C0A	alcohol dehydrogenase
AS19_12460	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
AS19_12490	ENOG4105D0M	Protease HtpX homolog
AS19_12500	ENOG4105DR4	Methyltransferase
AS19_12520	ENOG4105CHM	Aminotransferase
AS19_12550	ENOG4107SJW	iron permease, FTR1
AS19_12580	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AS19_12600	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AS19_12610	ENOG4105ERG	peptidase m48, ste24p
AS19_12620	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AS19_12640	ENOG4105D3G	Pseudouridine synthase
AS19_12650	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AS19_12670	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
AS19_12710	ENOG4108V1U	phospholipid-binding protein
AS19_12730	ENOG4107QIJ	Aconitate hydratase 2
AS19_12750	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
AS19_12760	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AS19_12770	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AS19_12790	ENOG4105CX6	glutaminyL-tRNA synthetase
AS19_12800	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AS19_12810	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AS19_12820	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AS19_12830	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AS19_12840	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AS19_12850	ENOG4105K70	DNA-binding protein
AS19_12860	ENOG4105EIN	peptidylprolyl cis-trans isomerase
AS19_12870	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
AS19_12880	ENOG4108JQ5	ABC transporter
AS19_12890	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
AS19_12900	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
AS19_12910	ENOG4105E43	Extracellular solute-binding protein, family 5
AS19_12920	ENOG4105E43	Extracellular solute-binding protein, family 5
AS19_12930	ENOG4105E9H	Lytic Murein transglycosylase
AS19_12940	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AS19_12960	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AS19_12970	ENOG4107RZZ	dna polymerase iii epsilon subunit
AS19_12980	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AS19_13000	ENOG4105E09	nadh pyrophosphatase
AS19_13020	ENOG4105ERU	peptidase
AS19_13040	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AS19_13050	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
AS19_13060	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AS19_13080	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AS19_13100	ENOG4105E39	Enoyl-CoA hydratase
AS19_13110	ENOG4107QX3	carboxylase
AS19_13120	ENOG4105C1G	acyl-Coa dehydrogenase
AS19_13150	ENOG4105BZU	Histidine kinase
AS19_13160	ENOG4105K4T	epimerase
AS19_13170	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AS19_13200	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AS19_13220	ENOG4108ZX5	transcriptional regulator
AS19_13230	ENOG4105EBR	Carboxylesterase
AS19_13240	ENOG4105M85	Bola protein
AS19_13250	ENOG4105C72	UPF0176 protein
AS19_13270	ENOG4105E0C	molybdate abc transporter
AS19_13280	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AS19_13340	ENOG4105BZU	Histidine kinase
AS19_13350	ENOG4105C1G	acyl-Coa dehydrogenase
AS19_13360	ENOG4105C1G	acyl-Coa dehydrogenase
AS19_13370	ENOG4108IXY	short-chain dehydrogenase reductase
AS19_13380	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AS19_13390	ENOG4107QP3	malate synthase g
AS19_13410	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AS19_13440	ENOG4105EZE	Cupin 4 family protein
AS19_13450	ENOG4107QTF	adenylosuccinate lyase
AS19_13460	ENOG41075W9	High frequency lysogenization protein HflD homolog
AS19_13470	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AS19_13490	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AS19_13500	ENOG4105M00	molybdopterin converting factor, subunit 1
AS19_13510	ENOG4108ZAF	Molybdopterin
AS19_13520	ENOG4108R99	pseudouridine synthase
AS19_13530	ENOG4105E9K	Isocitrate dehydrogenase
AS19_13550	ENOG4105VEQ	Cold shock protein
AS19_13570	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AS19_13580	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AS19_13590	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AS19_13600	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AS19_13610	ENOG4105C3M	thioredoxin reductase
AS19_13620	ENOG4105CNU	cell division protein FtsK
AS19_13630	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AS19_13640	ENOG4105D1H	recombination factor protein RarA
AS19_13650	ENOG4108ARY	Protein CrcB homolog
AS19_13660	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AS19_13670	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AS19_13680	ENOG4107QYG	anthranilate phosphoribosyltransferase
AS19_13710	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
AS19_13720	ENOG4108MN8	Membrane
AS19_13730	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
AS19_13750	ENOG4105D22	carbon starvation protein
AS19_13760	ENOG4105WH1	Two component transcriptional regulator luxr family
AS19_13770	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AS19_13790	ENOG4105BZU	Histidine kinase
AS19_13800	ENOG4105BZU	Histidine kinase
AS19_13810	ENOG4105M3Z	response regulator
AS19_13820	ENOG4107Z5C	methylesterase
AS19_13830	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AS19_13840	ENOG4107QHF	type ii secretion system protein e
AS19_13850	ENOG4105D7Q	type ii secretion system
AS19_13860	ENOG4108VAU	general secretion pathway protein G
AS19_13880	ENOG4105X5Z	General secretion pathway protein I
AS19_13890	ENOG4108WWZ	General secretion pathway protein J
AS19_13900	ENOG4108RTD	type II secretion system protein K
AS19_13960	ENOG4105C3R	Methionine synthase
AS19_13990	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AS19_14000	ENOG4105W8H	transhydrogenase (subunit alpha
AS19_14010	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AS19_14040	ENOG4105CN1	protease
AS19_14080	ENOG4107QUT	magnesium and cobalt transport protein CorA
AS19_14110	ENOG4105D1Q	UPF0246 protein
AS19_14130	ENOG4105Q9Y	Universal stress protein
AS19_14150	ENOG4105D4P	Coproporphyrinogen iii oxidase
AS19_14190	ENOG4105C58	cytochrome c oxidase accessory protein ccog
AS19_14200	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
AS19_14230	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AS19_14250	ENOG4105DND	Transcriptional regulator
AS19_14310	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AS19_14330	ENOG4105FE9	pseudouridine synthase
AS19_14340	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AS19_14360	ENOG4105C31	Tryptophanyl-tRNA synthetase
AS19_14370	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AS19_14380	ENOG4105DB7	PHP domain protein
AS19_14390	ENOG4107835	probably involved in intracellular septation (By similarity)
AS19_14400	ENOG4105K9H	YciI-like protein
AS19_14430	ENOG4106HNH	Acyl-transferase
AS19_14470	ENOG4108UJV	acyl-CoA thioesterase i
AS19_14480	ENOG4108I0Y	(ABC) transporter
AS19_14490	ENOG4105CV6	ABC transporter, permease
AS19_14500	ENOG4105C2C	drug resistance transporter, Bcr CflA
AS19_14520	ENOG4105W1Y	Transcriptional regulator
AS19_14540	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AS19_14550	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AS19_14560	ENOG4105CQB	FAD linked oxidase domain protein
AS19_14580	ENOG4108ZG0	Ompa motb domain protein
AS19_14590	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AS19_14600	ENOG4105D03	DNA-3-methyladenine glycosylase II
AS19_14660	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AS19_14700	ENOG4107QJE	Chromosome Partitioning Protein
AS19_14710	ENOG4105DC8	reductase
AS19_14720	ENOG4105CBC	glutamate synthase
AS19_14730	ENOG4105E4C	Lytic transglycosylase catalytic
AS19_14760	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AS19_14770	ENOG4105DXD	2-methylcitrate dehydratase
AS19_14780	ENOG4105C7F	AcnD-accessory protein PrpF
AS19_14790	ENOG4108I0Z	Aconitate hydratase
AS19_14800	ENOG4105BZN	citrate synthase
AS19_14810	ENOG4105CR4	methylisocitrate lyase
AS19_14820	ENOG4105DRR	Transcriptional regulator, GntR family
AS19_14840	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
AS19_14850	ENOG4107R11	Transcriptional regulator
AS19_14920	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AS19_14930	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
AS19_14940	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
AS19_14950	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
AS19_14960	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AS19_14970	ENOG4105CQ7	ATP-dependent helicase
AS19_14990	ENOG4105F8C	transglutaminase domain-containing protein
AS19_15010	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AS19_15020	ENOG4105C28	cystathionine
AS19_15030	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AS19_15050	ENOG4105E96	Colicin v production protein
AS19_15070	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AS19_15080	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AS19_15090	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AS19_15100	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AS19_15110	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AS19_15120	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AS19_15140	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AS19_15150	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AS19_15160	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AS19_15180	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AS19_15190	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AS19_15200	ENOG4108MP6	LysR family Transcriptional regulator
AS19_15220	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AS19_15230	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AS19_15270	ENOG4105CK2	sodium dicarboxylate symporter
AS19_15290	ENOG4105EMU	Dehydrogenase
AS19_15360	ENOG4105CGK	Exodeoxyribonuclease III
AS19_15380	ENOG4108BY2	phosphohistidine phosphatase
AS19_15390	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AS19_15400	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AS19_15430	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AS19_15440	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AS19_15460	ENOG4105C7S	Dehydrogenase
AS19_15470	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AS19_15480	ENOG4105E33	succinate dehydrogenase
AS19_15490	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AS19_15500	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
AS19_15510	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
AS19_15520	ENOG4105BZN	citrate synthase
AS19_15540	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AS19_15600	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AS19_15630	ENOG4105CHH	sulfate transporter
AS19_15640	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AS19_15650	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AS19_15690	ENOG4105E18	UPF0276 protein
AS19_15720	ENOG4105CQ7	ATP-dependent helicase
AS19_15770	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AS19_15790	ENOG4105CDV	Ompa motb domain protein
AS19_15810	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
AS19_15940	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AS19_15950	ENOG4107S2Z	UPF0761 membrane protein
AS19_15960	ENOG4105K89	arsenate reductase
AS19_15970	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AS19_16030	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AS19_16050	ENOG4108BPE	-transporting atpase
AS19_16060	ENOG4107QI1	Mate efflux family protein
AS19_16120	ENOG4105EYM	Major Facilitator superfamily
AS19_16130	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
AS19_16140	ENOG4105CIY	formyltetrahydrofolate deformylase
AS19_16150	ENOG4108ZX5	transcriptional regulator
AS19_16170	ENOG4108MGY	Histidine kinase
AS19_16180	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AS19_16190	ENOG4105CHU	acetyl-coa acetyltransferase
AS19_16230	ENOG4108DG9	Smr protein MutS2
AS19_16240	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
AS19_16250	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
AS19_16270	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AS19_16280	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AS19_16310	ENOG4105DHP	deoxycytidine triphosphate deaminase
AS19_16370	ENOG4105KT5	UmuD protein
AS19_16400	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AS19_16410	ENOG4107SC1	transglycosylase
AS19_16420	ENOG4105IH7	synthase
AS19_16460	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
AS19_16490	ENOG4105C7I	Dehydrogenase
AS19_16520	ENOG4105BZU	Histidine kinase
AS19_16530	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AS19_16540	ENOG4105VP2	Transcriptional regulator, Crp Fnr family
AS19_16550	ENOG4105MP9	class II Aldolase
AS19_16640	ENOG4105DGN	Electron transport complex
AS19_16650	ENOG4108R3D	Electron transport complex
AS19_16670	ENOG4105D6A	Electron transport complex
AS19_16680	ENOG4108UQQ	Electron transport complex
AS19_16690	ENOG4105DZB	Electron transport complex
AS19_16710	ENOG4105D6U	Sodium Glutamate Symporter
AS19_16720	ENOG4105CSM	endonuclease III
AS19_16740	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AS19_16770	ENOG4105DXN	mazG family
AS19_16780	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AS19_16790	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AS19_16810	ENOG4105C6T	cysteine synthase
AS19_16820	ENOG4105BZU	Histidine kinase
AS19_16830	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AS19_16850	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AS19_16860	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AS19_16880	ENOG4105C3F	Signal peptidase i
AS19_16890	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AS19_16900	ENOG4105C0H	protease
AS19_16920	ENOG4105VQK	sigma E regulatory protein, MucB RseB
AS19_16930	ENOG41069E1	anti sigma-E protein RseA
AS19_16940	ENOG4105EMN	RNA polymerase sigma factor
AS19_16960	ENOG4108IYU	L-aspartate oxidase
AS19_17000	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AS19_17010	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AS19_17020	ENOG4108RFG	Tetr family transcriptional regulator
AS19_17030	ENOG4105CRK	lysyL-tRNA synthetase
AS19_17060	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AS19_17070	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AS19_17080	ENOG4105CHU	acetyl-coa acetyltransferase
AS19_17160	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
AS19_17170	ENOG4105DVC	DnaJ domain protein
AS19_17180	ENOG4105J5T	Amp-dependent synthetase and ligase
AS19_17210	ENOG4105C4R	Atp-dependent dna helicase
AS19_17290	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AS19_17320	ENOG4105MYN	Zinc uptake regulation protein
AS19_17350	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS19_17390	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AS19_17410	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AS19_17430	ENOG4105D05	Receptor
AS19_17440	ENOG410804D	Sensor Signal Transduction Histidine Kinase
AS19_17450	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AS19_17510	ENOG4105C1J	atp-dependent rna helicase
AS19_17520	ENOG4105WKW	Pfam:DUF1458
AS19_17530	ENOG4108TKH	Nitroreductase
AS19_17570	ENOG4105C1G	acyl-Coa dehydrogenase
AS19_17580	ENOG4105C1G	acyl-Coa dehydrogenase
AS19_17610	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AS19_17650	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AS19_17680	ENOG4105CHU	acetyl-coa acetyltransferase
AS19_17690	ENOG4105CHR	reductase
AS19_17710	ENOG4108ZX5	transcriptional regulator
AS19_17740	ENOG4105EJ2	Transcriptional regulator
AS19_17760	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
AS19_17770	ENOG4107T9Q	phosphonate abc transporter
AS19_17780	ENOG4105D5T	phosphonate abc transporter
AS19_17790	ENOG4105S7S	phosphonate abc transporter
AS19_17800	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AS19_17810	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
AS19_17840	ENOG4106FVC	RNA methyltransferase
AS19_17850	ENOG4105EGS	Mechanosensitive ion channel
AS19_17870	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AS19_17900	ENOG4108TEM	pseudouridine methyltransferase
AS19_17930	ENOG4105C5H	ABC transporter
AS19_17960	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AS19_17990	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AS19_18000	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AS19_18010	ENOG4105CAT	Cytidine monophosphate kinase
AS19_18020	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AS19_18030	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AS19_18050	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AS19_18060	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AS19_18070	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AS19_18080	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AS19_18090	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AS19_18100	ENOG4105UBK	short-chain dehydrogenase reductase
AS19_18110	ENOG4108821	RND type efflux pump
AS19_18120	ENOG4108821	RND type efflux pump
AS19_18130	ENOG4108821	RND type efflux pump
AS19_18160	ENOG4108821	RND type efflux pump
AS19_18190	ENOG4105K59	histidine triad (HIT) protein
AS19_18210	ENOG4108ZZ3	UPF0260 protein
AS19_18220	ENOG4105VNG	YcgL domain-containing protein
AS19_18230	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AS19_18240	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AS19_18250	ENOG4108821	RND type efflux pump
AS19_18260	ENOG4105C1G	acyl-Coa dehydrogenase
AS19_18270	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AS19_18280	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AS19_18290	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AS19_18300	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AS19_18330	ENOG4108RMJ	sensory transduction regulator
AS19_18340	ENOG4105U3E	Transcriptional regulator
AS19_18370	ENOG4108TSE	Transferase
AS19_18390	ENOG4105CEY	Amp-dependent synthetase and ligase
AS19_18460	ENOG4105CYC	Transferase
AS19_18480	ENOG4105CKI	cobalamin synthesis protein
AS19_18490	ENOG4105EKE	dihydroorotase
AS19_18500	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AS19_18510	ENOG4105CFH	Aspartokinase
AS19_18520	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AS19_18530	ENOG4105EJ9	Membrane
AS19_18540	ENOG4105Y3E	Modulates RecA activity (By similarity)
AS19_18550	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AS19_18560	ENOG4107TH8	cina domain protein
AS19_18570	ENOG4105CDY	transcriptional regulatory protein
AS19_18600	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
AS19_18680	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AS19_18690	ENOG4108Z4U	Ferredoxin
AS19_18750	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AS19_18760	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AS19_18770	ENOG4105DSY	exodeoxyribonuclease V, gamma
AS19_18780	ENOG4107QKA	exodeoxyribonuclease V beta
AS19_18790	ENOG4107QYX	exodeoxyribonuclease v alpha
AS19_18800	ENOG4105CDV	Ompa motb domain protein
AS19_18810	ENOG4105WXT	Conserved Protein
AS19_18820	ENOG410689M	(LipO)protein
AS19_18850	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AS19_18870	ENOG4105DZR	Type I site-specific deoxyribonuclease
AS19_18900	ENOG4105EKX	Restriction modification system DNA (Specificity
AS19_18910	ENOG4105CVR	type I restriction-modification system
AS19_18930	ENOG4107YU2	histidine triad (hIT) protein
AS19_18950	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AS19_18960	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AS19_18970	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AS19_18980	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AS19_18990	ENOG41082NX	50s ribosomal protein l35
AS19_19000	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AS19_19020	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
AS19_19040	ENOG4105CH6	catalase
AS19_19050	ENOG4105CMI	transporter
AS19_19060	ENOG4105CJ1	ABC, transporter
AS19_19070	ENOG4105D0S	secretion protein (HlyD
AS19_19080	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AS19_19120	ENOG4105C2C	drug resistance transporter, Bcr CflA
AS19_19140	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AS19_19150	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AS19_19160	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AS19_19170	ENOG4105BZU	Histidine kinase
AS19_19200	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AS19_19210	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AS19_19230	ENOG4105CUT	histidyl-tRNA synthetase
AS19_19240	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AS19_19250	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AS19_19270	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AS19_19280	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AS19_19310	ENOG4105C3K	feS assembly ATPase SufC
AS19_19330	ENOG4105C9B	Cysteine desulfurase
AS19_19340	ENOG4108Z4V	iron-sulfur cluster assembly
AS19_19360	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AS19_19370	ENOG4105C3J	Cysteine desulfurase
AS19_19380	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AS19_19420	ENOG4105HA9	of methanol dehydrogenase type
AS19_19430	ENOG4108V0P	LemA family
AS19_19440	ENOG41082IR	Excinuclease ABC C subunit domain protein
AS19_19510	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AS19_19530	ENOG4105EIG	urea carboxylase-associated protein 1
AS19_19540	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AS19_19570	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
AS19_19600	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
AS19_19620	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AS19_19680	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
AS19_19690	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AS19_19710	ENOG4108V0P	LemA family
AS19_19720	ENOG4105D0M	Protease HtpX homolog
AS19_19760	ENOG4107RJ1	sodium solute
AS19_19840	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AS19_19850	ENOG4105EIF	outer membrane protein W
AS19_19870	ENOG4108IAB	Phoh family
AS19_19960	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AS19_19980	ENOG4105C9A	Phoh family
AS19_19990	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AS19_20000	ENOG4108JU5	Magnesium and cobalt efflux protein
AS19_20030	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AS19_20070	ENOG4107QPB	Beta-lactamase domain protein
AS19_20090	ENOG41080C8	DUF218 domain
AS19_20100	ENOG4105C8T	Leucyl-tRNA synthetase
AS19_20150	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AS19_20180	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AS19_20190	ENOG4105CJN	penicillin-binding protein
AS19_20200	ENOG4105CNI	cell division protein FtsW
AS19_20210	ENOG4105CVE	Lytic murein transglycosylase
AS19_20230	ENOG4105DZ1	carboxypeptidase
AS19_20240	ENOG4105F0I	Aminotransferase
AS19_20250	ENOG4108Z43	UPF0250 protein
AS19_20270	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AS19_20280	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AS19_20300	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
AS19_20370	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AS19_20390	ENOG4105DFU	Cell wall formation (By similarity)
AS19_20400	ENOG4107IFA	Lipase (EC 3.1.1.3)
AS19_20440	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
AS19_20450	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
AS19_20460	ENOG4108IV0	ABC, transporter
AS19_20480	ENOG4105CNN	ABC, transporter
AS19_20490	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AS19_20500	ENOG41083Z3	extracellular ligand-binding receptor
AS19_20510	ENOG4105BZU	Histidine kinase
AS19_20520	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AS19_20540	ENOG4105CTQ	phosphohexokinase
AS19_20550	ENOG4105C2W	permease
AS19_20560	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AS19_20580	ENOG4105C72	UPF0176 protein
AS19_20590	ENOG4105F0N	pyrophosphate phospho-hydrolase
AS19_20600	ENOG4108R6W	Transcriptional regulator, ARAC family
AS19_20620	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AS19_20630	ENOG4105FQR	PH-inducible protein involved in stress response
AS19_20650	ENOG4105DHQ	Histidine kinase
AS19_20660	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AS19_20670	ENOG41081YB	ApbE family
AS19_20700	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS19_20710	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AS19_20720	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AS19_20730	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AS19_20740	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AS19_20750	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AS19_20770	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AS19_20780	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AS19_20790	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AS19_20800	ENOG4105C12	Phosphoribosylglycinamide synthetase
AS19_20820	ENOG4105BZU	Histidine kinase
AS19_20830	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AS19_20840	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
AS19_20850	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AS19_20860	ENOG4108UKZ	OsmC family
AS19_20870	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AS19_20880	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AS19_20890	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AS19_20900	ENOG4105DDQ	anthranilate synthase
AS19_20910	ENOG4105CRQ	synthase (Component I)
AS19_20950	ENOG4108UYB	regulatoR
AS19_20960	ENOG4105TX3	Histidine kinase
AS19_20980	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
AS19_20990	ENOG4105CCU	oxidase (Subunit III)
AS19_21000	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AS19_21010	ENOG4105E2S	oxidase) subunit II
AS19_21020	ENOG4105CSH	Transporter
AS19_21050	ENOG4107TT5	NLP P60 protein
AS19_21060	ENOG4105DJV	ribulose-phosphate 3-epimerase
AS19_21070	ENOG4108S0S	Nucleotidyl transferase
AS19_21080	ENOG4105EHM	Aminoglycoside phosphotransferase
AS19_21090	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AS19_21100	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AS19_21110	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AS19_21120	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AS19_21130	ENOG4105NWN	ApaG protein
AS19_21160	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AS19_21170	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AS19_21200	ENOG4105EUJ	GTP cyclohydrolase i
AS19_21210	ENOG4107ZVW	dihydroneopterin aldolase
AS19_21220	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AS19_21230	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AS19_21240	ENOG4105VCC	30S ribosomal protein S21
AS19_21250	ENOG4105KTH	gatB Yqey
AS19_21260	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AS19_21320	ENOG4105R8A	Heat shock protein
AS19_21340	ENOG4105C1J	atp-dependent rna helicase
AS19_21370	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
AS19_21390	ENOG4105E0K	tonB-dependent siderophore receptor
AS19_21430	ENOG4105IBP	Cyclic peptide transporter
AS19_21460	ENOG4105CSU	acyl-Coa dehydrogenase
AS19_21470	ENOG4105D82	Glutamate dehydrogenase
AS19_21480	ENOG4107R37	Glutamate dehydrogenase
AS19_21490	ENOG4105WD1	Membrane
AS19_21500	ENOG4105CSU	acyl-Coa dehydrogenase
AS19_21510	ENOG4105W49	UPF0434 protein
AS19_21520	ENOG4105HDD	phospholipase
AS19_21550	ENOG4107RN6	Monooxygenase
AS19_21570	ENOG4105EMU	Dehydrogenase
AS19_21600	ENOG4108IXY	short-chain dehydrogenase reductase
AS19_21610	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
AS19_21680	ENOG4108DEF	Globin
AS19_21720	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AS19_21730	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AS19_21780	ENOG4105EA8	2-Nitropropane dioxygenase
AS19_21800	ENOG4105K78	MarR family Transcriptional regulator
AS19_21820	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AS19_21830	ENOG4105C22	threonyL-tRNA synthetase
AS19_21840	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AS19_21850	ENOG4105C8N	cysteinyl-tRNA synthetase
AS19_21900	ENOG4105UGU	tonB-dependent Receptor
AS19_21940	ENOG4105CK7	Sodium proline symporter
AS19_21970	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AS19_21990	ENOG4108KJ1	Trap dicarboxylate transporter, dctp subunit
AS19_22000	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AS19_22010	ENOG4108K1J	Transporter DctQ
AS19_22040	ENOG4108JPW	Aminotransferase
AS19_22050	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
AS19_22080	ENOG4105BZU	Histidine kinase
AS19_22120	ENOG4107QN1	sodium solute
AS19_22160	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
AS19_22180	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AS19_22190	ENOG4105CTB	Polyprenyl synthetase
AS19_22200	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AS19_22220	ENOG4108ZAI	phosphatidylglycerophosphatase a
AS19_22230	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AS19_22240	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AS19_22250	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AS19_22260	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AS19_22280	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AS19_22290	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AS19_22300	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AS19_22310	ENOG4105C5H	ABC transporter
AS19_22330	ENOG4105EMN	RNA polymerase sigma factor
AS19_22390	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AS19_22400	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AS19_22410	ENOG4105CDU	Replicative dna helicase
AS19_22420	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AS19_22430	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AS19_22450	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AS19_22460	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AS19_22470	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AS19_22510	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AS19_22520	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
AS19_22540	ENOG4105EPW	hflc protein
AS19_22550	ENOG4107QJR	hflk protein
AS19_22560	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AS19_22570	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AS19_22580	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AS19_22590	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AS19_22600	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AS19_22610	ENOG4105K8N	protein family UPF0079, ATPase
AS19_22620	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AS19_22630	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AS19_22640	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AS19_22650	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AS19_22670	ENOG4105KHC	sulfurtransferase
AS19_22680	ENOG4105DJ4	phosphatidylserine decarboxylase
AS19_22710	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AS19_22720	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AS19_22730	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AS19_22740	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AS19_22750	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AS19_22760	ENOG4105MJ2	Competence protein
AS19_22780	ENOG4105C1G	acyl-Coa dehydrogenase
AS19_22800	ENOG41090A4	Pterin carbinolamine dehydratase
AS19_22820	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AS19_22830	ENOG4105BZ8	glutamate synthase
AS19_22840	ENOG4105CBC	glutamate synthase
AS19_22860	ENOG4105D49	3-dehydroquinate synthase
AS19_22870	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AS19_22880	ENOG4105E4G	Type IV pilus
AS19_22930	ENOG4108JQC	penicillin-binding protein 1A
AS19_22940	ENOG4105C6K	Malic enzyme
AS19_22950	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AS19_22960	ENOG4105C25	Primosomal protein n'
AS19_22970	ENOG4105C75	arginyL-tRNA synthetase
AS19_22990	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AS19_23000	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AS19_23020	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AS19_23040	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AS19_23050	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
AS19_23060	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AS19_23070	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AS19_23120	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AS19_23150	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AS19_23160	ENOG4105CUX	Signal transduction histidine kinase
AS19_23180	ENOG4105C5F	glutamine synthetase
AS19_23200	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AS19_23210	ENOG4105E68	Sulfatase
AS19_23250	ENOG4105CI3	gtp-binding protein typa
AS19_23270	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AS19_23280	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AS19_23290	ENOG4105VW4	glutaredoxin 3
AS19_23300	ENOG4107YZP	Rhodanese domain protein
AS19_23310	ENOG41063SB	peptidase
AS19_23320	ENOG4105CN1	protease
AS19_23330	ENOG4105PXI	polysaccharide deacetylase
AS19_23340	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AS19_23350	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AS19_23360	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AS19_23370	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AS19_23390	ENOG4105BZU	Histidine kinase
AS19_23410	ENOG4105CEN	a g-specific adenine glycosylase
AS19_23420	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AS19_23500	ENOG41067CV	Integrase
AS19_23520	ENOG4108K0D	peptidase, M48
AS19_23530	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AS19_23550	ENOG4105D1S	lipid A biosynthesis
AS19_23580	ENOG4108SHN	Glycosyl transferase, family 2
AS19_23590	ENOG4107543	(lipo)polysaccharide
AS19_23600	ENOG4107RJ7	Glycosyl transferase (Group 1
AS19_23610	ENOG4105D16	lipopolysaccharide heptosyltransferase i
AS19_23630	ENOG4105XA0	heptosyltransferase ii
AS19_23640	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AS19_23650	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AS19_23660	ENOG4107QHF	type ii secretion system protein e
AS19_23670	ENOG4107IX6	phosphate transport regulator
AS19_23680	ENOG4105CJ3	phosphate transporter
AS19_23690	ENOG4107QZM	n-acetylglutamate synthase
AS19_23800	ENOG4105F1S	paraquat-inducible protein a
AS19_23810	ENOG4105DY2	Paraquat-inducible protein b
AS19_23840	ENOG4105ECF	c-methyltransferase
AS19_23850	ENOG41076E6	Uroporphyrinogen-III Synthase
AS19_23860	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AS19_23870	ENOG4108NEV	two component transcriptional regulator, LytTR family
AS19_23880	ENOG4108HRK	Histidine kinase
AS19_23890	ENOG4105CH7	arginosuccinase
AS19_23900	ENOG4105NXH	GreA GreB family elongation factor
AS19_23920	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AS19_23930	ENOG4105DFD	Na H antiporter
AS19_23950	ENOG4105D6S	protein involved in catabolism of external DNA
AS19_23960	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AS19_23980	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AS19_24000	ENOG4105WP7	tRNA pseudouridine synthase C
AS19_24070	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AS19_24090	ENOG4105HF0	Membrane
AS19_24110	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
AS19_24120	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AS19_24160	ENOG4105C59	p-type ATPase
AS19_24170	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AS19_24220	ENOG4105E3B	Multicopper oxidase
AS19_24240	ENOG41077A9	carbonic anhydrase
AS19_24250	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AS19_24260	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AS19_24270	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AS19_24280	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AS19_24290	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AS19_24300	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AS19_24310	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AS19_24320	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
AS19_24330	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AS19_24340	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AS19_24360	ENOG4105CA0	peroxidase
AS19_24380	ENOG4105EFT	decarboxylase
AS19_24390	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AS19_24400	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AS19_24420	ENOG4108YZT	Adenosylcobinamide kinase
AS19_24430	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AS19_24440	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AS19_24450	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AS19_24480	ENOG4105C5X	domain protein
AS19_24520	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
AS19_24530	ENOG4105C5I	Dehydrogenase
AS19_24550	ENOG4105F95	Monooxygenase
AS19_24580	ENOG4105VQD	rieske 2fe-2S domain-containing protein
AS19_24590	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AS19_24600	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AS19_24630	ENOG4108PTX	LysR family Transcriptional regulator
AS19_24660	ENOG4105DY2	Paraquat-inducible protein b
AS19_24670	ENOG4105F1S	paraquat-inducible protein a
AS19_24690	ENOG4105C1J	atp-dependent rna helicase
AS19_24720	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AS19_24730	ENOG4105DH7	May be involved in recombination (By similarity)
AS19_24750	ENOG4105CPT	Alpha beta hydrolase
AS19_24760	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AS19_24780	ENOG4108WUH	Transcriptional regulator, TetR family
AS19_24790	ENOG4108I6A	alcohol dehydrogenase
AS19_24810	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AS19_24820	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AS19_24830	ENOG4108821	RND type efflux pump
AS19_24840	ENOG4105CNG	UPF0061 protein
AS19_24850	ENOG4105CYM	Glutathione S-transferase
AS19_24870	ENOG4105DND	Transcriptional regulator
AS19_24920	ENOG4105D3R	alkyl hydroperoxide reductase
AS19_24940	ENOG4105BZU	Histidine kinase
AS19_24950	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AS19_24980	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AS19_24990	ENOG4105J0Q	Transcriptional regulator
AS19_25010	ENOG41060WC	Enoyl-CoA hydratase
AS19_25030	ENOG4105EAC	phosphoserine phosphatase
AS19_25040	ENOG4105BZU	Histidine kinase
AS19_25060	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AS19_25070	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AS19_25080	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AS19_25100	ENOG4105F2Z	3-oxoadipate enol-lactonase
AS19_25120	ENOG4105CHU	acetyl-coa acetyltransferase
AS19_25130	ENOG4107QPN	acyl-Coa dehydrogenase
AS19_25170	ENOG4108RRZ	Transcription elongation factor GreB
AS19_25190	ENOG4105D52	delta-aminolevulinic acid dehydratase
AS19_25210	ENOG4105C9X	ppx gppa phosphatase
AS19_25220	ENOG4105K63	Thioredoxin
AS19_25230	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AS19_25250	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AS19_25300	ENOG4105D05	Receptor
AS19_25310	ENOG4105DV0	amidase (EC 3.5.1.4
AS19_25320	ENOG4105CIS	alcohol dehydrogenase
AS19_25350	ENOG4105CNM	Receptor
AS19_25370	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
AS19_25400	ENOG4106HNH	Acyl-transferase
AS19_25410	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AS19_25420	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AS19_25430	ENOG4105IPS	esterase
AS19_25440	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AS19_25450	ENOG4108SX3	cytoplasmic protein
AS19_25460	ENOG41087AY	ADP-Ribose pyrophosphatase
AS19_25470	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AS19_25480	ENOG4105DFG	type I secretion outer membrane protein
AS19_25490	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AS19_25500	ENOG41087SS	fad dependent oxidoreductase
AS19_25510	ENOG4105CPC	Aldo Keto reductase
AS19_25580	ENOG4105C32	Amino acid ABC transporter (Permease)
AS19_25600	ENOG4105C0Z	ABC transporter
AS19_25610	ENOG4108IV0	ABC, transporter
AS19_25630	ENOG4105C09	Bile acid
AS19_25650	ENOG4105BZU	Histidine kinase
AS19_25670	ENOG4108ZXC	Two component transcriptional regulator, luxr family
AS19_25680	ENOG4105BZU	Histidine kinase
AS19_25700	ENOG4105BZS	acriflavin resistance protein
AS19_25710	ENOG4105D0S	secretion protein (HlyD
AS19_25800	ENOG4105W0Z	cytoplasmic protein
AS19_25810	ENOG4105C0P	Mg chelatase subunit ChlI
AS19_25830	ENOG4105CHR	reductase
AS19_25850	ENOG4108ZX5	transcriptional regulator
AS19_25860	ENOG4105I08	Pseudouridine synthase
AS19_25870	ENOG4105C4R	Atp-dependent dna helicase
AS19_25890	ENOG4105MPD	Cytochrome
AS19_26060	ENOG4105CGU	Enoyl-CoA hydratase
AS19_26090	ENOG4105EGS	Mechanosensitive ion channel
AS19_26130	ENOG4106H78	methyltransferase
AS19_26160	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AS19_26170	ENOG4105CAK	Cell division ATP-binding protein ftsE
AS19_26180	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AS19_26190	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AS19_26210	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AS19_26220	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AS19_26230	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AS19_26260	ENOG4105DWV	Homoserine O-trans-acetylase
AS19_26270	ENOG4105DWV	Homoserine O-trans-acetylase
AS19_26280	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AS19_26290	ENOG4108UPT	UPF0178 protein
AS19_26300	ENOG4105CSA	Coproporphyrinogen iii oxidase
AS19_26310	ENOG4108RZE	Tetr family transcriptional regulator
AS19_26330	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AS19_26380	ENOG410829K	Lysine exporter protein (Lyse ygga)
AS19_26390	ENOG4105DQ6	Transposase
AS19_26490	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS19_26500	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS19_26510	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AS19_26520	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AS19_26540	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
AS19_26550	ENOG4107QKW	extracellular solute-binding protein family 1
AS19_26560	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AS19_26570	ENOG4105D0A	hydroxylase
AS19_26580	ENOG4107RAQ	aminopeptidase
AS19_26610	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AS19_26630	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AS19_26650	ENOG4105C7B	Threonine dehydratase
AS19_26660	ENOG4105E66	phosphoriboisomerase A
AS19_26720	ENOG4105D2N	Aldolase
AS19_26730	ENOG4105BZA	Phosphoglycerate kinase
AS19_26760	ENOG41080HT	Transcriptional regulator, arsr family
AS19_26770	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AS19_26780	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AS19_26790	ENOG4105SYT	Methylenetetrahydrofolate reductase
AS19_26810	ENOG4105CA9	Pyruvate kinase
AS19_26840	ENOG4105C3S	Mate efflux family protein
AS19_26870	ENOG4105NBK	UPF0345 protein
AS19_26930	ENOG4105EHV	domain protein
AS19_26950	ENOG4108UT2	hemolysin iii
AS19_26960	ENOG41080HT	Transcriptional regulator, arsr family
AS19_26990	ENOG4108V06	Glutathione peroxidase
AS19_27020	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
AS19_27070	ENOG4106RE7	Cytochrome
AS19_27080	ENOG4105MPD	Cytochrome
AS19_27090	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AS19_27110	ENOG4105KJM	monovalent cation h antiporter subunit g
AS19_27120	ENOG4105W4C	monovalent cation H antiporter subunit F
AS19_27130	ENOG4105SC1	monovalent cation H antiporter subunit E
AS19_27140	ENOG4107R4Z	monovalent cation h antiporter subunit d
AS19_27150	ENOG4108ZE9	Monovalent cation H antiporter subunit C
AS19_27160	ENOG4105D65	subunit l
AS19_27170	ENOG4105C2M	dna polymerase I
AS19_27200	ENOG4105C1G	acyl-Coa dehydrogenase
AS19_27230	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AS19_27240	ENOG4105BZU	Histidine kinase
AS19_27250	ENOG4108VIA	integral membrane protein
AS19_27260	ENOG4105II7	pyrroline-5-carboxylate reductase
AS19_27270	ENOG4105DFA	alanine racemase domain protein
AS19_27280	ENOG4105CZX	twitching motility protein
AS19_27290	ENOG4105CZX	twitching motility protein
AS19_27300	ENOG41069P5	Protein slyX homolog
AS19_27320	ENOG4108VWS	Yaeq family
AS19_27350	ENOG4105CAU	Arsenical resistance protein, ArsH
AS19_27360	ENOG4105D6J	arsenicaL-resistance protein
AS19_27370	ENOG4107WAU	Protein tyrosine phosphatase
AS19_27380	ENOG41082YX	Transcriptional regulator, arsr family
AS19_27390	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AS19_27400	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AS19_27410	ENOG4105E2Z	phosphate ABC transporter (Permease
AS19_27420	ENOG4105C8U	phosphate abc transporter
AS19_27450	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AS19_27460	ENOG4105NAU	thioesterase Superfamily protein
AS19_27470	ENOG4105CH5	extracellular solute-binding protein, family 7
AS19_27480	ENOG4105C4R	Atp-dependent dna helicase
AS19_27490	ENOG4105BZU	Histidine kinase
AS19_27520	ENOG4105D8X	mechanosensitive ion channel
AS19_27560	ENOG4107RZC	phospholipase d
AS19_27580	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
AS19_27600	ENOG4105E0X	reductase
AS19_27610	ENOG4105CKW	Inner membrane protein yedI
AS19_27630	ENOG4108KQI	regulatory protein luxr
AS19_27640	ENOG4105EEF	Alkane 1-monooxygenase
AS19_27650	ENOG41084UD	rubredoxin
AS19_27810	ENOG4105YGK	Pfam:UPF0157
AS19_27830	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
AS19_27840	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
AS19_27850	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
AS19_27870	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
AS19_27880	ENOG4105CQM	Urea amidohydrolase subunit alpha
AS19_27890	ENOG4105KI2	Urea amidohydrolase subunit beta
AS19_27900	ENOG4108YZ9	Urea amidohydrolase subunit gamma
AS19_27910	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
AS19_27920	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AS19_27930	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AS19_27940	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AS19_27950	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AS19_27960	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AS19_27970	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AS19_27980	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AS19_27990	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AS19_28000	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AS19_28010	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AS19_28030	ENOG4105FA0	parb-like partition protein
AS19_28040	ENOG4107QJE	Chromosome Partitioning Protein
AS19_28050	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AS19_28060	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AS19_28070	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
AS19_28080	ENOG4105CSU	acyl-Coa dehydrogenase
AS19_28100	ENOG4107RET	Isocitrate lyase
AS19_28110	ENOG4105D8T	Acyltransferase
AS19_28120	ENOG4105DSB	aldose 1-epimerase
AS19_28130	ENOG4105VEQ	Cold shock protein
AS19_28150	ENOG4105BZS	acriflavin resistance protein
AS19_28170	ENOG4105CEY	Amp-dependent synthetase and ligase
AS19_28180	ENOG4105C9Q	fumarate hydratase class II
AS19_28190	ENOG4105M4P	Tetr family transcriptional regulator
AS19_28210	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AS19_28220	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AS19_28240	ENOG4105VG0	50S ribosomal protein l34