locus-tag	class	description
AS19_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AS19_00080	COG0751	glycine-tRNA ligase activity
AS19_00090	COG0752	glycyl-tRNA synthetase alpha subunit
AS19_00100	COG2818	Glycosylase
AS19_00140	COG1160	GTP binding
AS19_00150	COG1846	Transcriptional regulator
AS19_00180	COG1566	PFAM secretion protein HlyD family protein
AS19_00220	COG1960	acyl-CoA dehydrogenase activity
AS19_00240	COG5285	phytanoyl-CoA dioxygenase
AS19_00250	COG5487	UPF0391 membrane protein
AS19_00270	COG0435	Glutathione S-transferase
AS19_00280	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AS19_00290	COG0583	DNA-binding transcription factor activity
AS19_00320	COG0745	RESPONSE REGULATOR receiver
AS19_00330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS19_00360	COG0540	Belongs to the ATCase OTCase family
AS19_00370	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AS19_00380	COG3038	cytochrome b561
AS19_00390	COG2353	YceI-like domain
AS19_00450	COG0678	peroxiredoxin activity
AS19_00490	COG1666	GTP binding
AS19_00520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AS19_00520	COG0519	Catalyzes the synthesis of GMP from XMP
AS19_00550	COG0110	maltose O-acetyltransferase activity
AS19_00590	COG4399	Belongs to the UPF0754 family
AS19_00650	COG1944	ATP diphosphatase activity
AS19_00670	COG2703	oxygen carrier activity
AS19_00690	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS19_00700	COG0277	FAD linked oxidase domain protein
AS19_00710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS19_00780	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AS19_00780	COG0475	glutathione-regulated potassium exporter activity
AS19_00790	COG4773	Receptor
AS19_00810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS19_00830	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AS19_00870	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AS19_00900	COG1309	transcriptional regulator
AS19_00910	COG0429	hydrolase of the alpha beta-hydrolase fold
AS19_00920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AS19_00980	COG0330	HflC and HflK could
AS19_01010	COG3038	cytochrome b561
AS19_01050	COG2201	protein-glutamate methylesterase activity
AS19_01080	COG0840	transmembrane signaling receptor activity
AS19_01150	COG1678	Uncharacterized ACR, COG1678
AS19_01160	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AS19_01200	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AS19_01210	COG0583	DNA-binding transcription factor activity
AS19_01260	COG3239	Fatty acid desaturase
AS19_01280	COG3121	Chaperone
AS19_01290	COG3188	usher protein
AS19_01310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS19_01320	COG0569	domain protein
AS19_01330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AS19_01340	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AS19_01350	COG0242	peptide deformylase activity
AS19_01370	COG0758	DNA mediated transformation
AS19_01380	COG0009	L-threonylcarbamoyladenylate synthase
AS19_01390	COG0408	coproporphyrinogen oxidase activity
AS19_01400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AS19_01430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AS19_01450	COG0339	signal peptide processing
AS19_01520	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AS19_01530	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS19_01530	COG1024	Enoyl-CoA hydratase
AS19_01580	COG1278	Cold shock
AS19_01600	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AS19_01610	COG1121	(ABC) transporter
AS19_01620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS19_01630	COG0534	Mate efflux family protein
AS19_01640	COG2199	diguanylate cyclase activity
AS19_01670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS19_01680	COG1773	rubredoxin
AS19_01690	COG3161	chorismate lyase activity
AS19_01700	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AS19_01730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AS19_01740	COG0583	DNA-binding transcription factor activity
AS19_01760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AS19_01770	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AS19_01810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AS19_01830	COG1758	RNA polymerase activity
AS19_01840	COG0194	GDP metabolic process
AS19_01850	COG3608	succinylglutamate desuccinylase aspartoacylase
AS19_01860	COG0129	dihydroxy-acid dehydratase activity
AS19_01900	COG0318	PFAM AMP-dependent synthetase and ligase
AS19_01910	COG1960	acyl-CoA dehydrogenase activity
AS19_02050	COG1309	transcriptional regulator
AS19_02070	COG0633	Ferredoxin
AS19_02120	COG1561	YicC-like family, N-terminal region
AS19_02130	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AS19_02140	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AS19_02160	COG1309	transcriptional regulator
AS19_02170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AS19_02190	COG0756	dUTP diphosphatase activity
AS19_02200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AS19_02210	COG2003	Belongs to the UPF0758 family
AS19_02220	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AS19_02230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AS19_02270	COG4964	Belongs to the GSP D family
AS19_02410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS19_02470	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AS19_02530	COG0789	Transcriptional regulator
AS19_02550	COG3530	Putative quorum-sensing-regulated virulence factor
AS19_02570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AS19_02580	COG0577	efflux transmembrane transporter activity
AS19_02580	COG1136	(ABC) transporter
AS19_02590	COG1538	Outer membrane efflux protein
AS19_02600	COG0123	including yeast histone deacetylase and acetoin utilization protein
AS19_02620	COG0183	Belongs to the thiolase family
AS19_02630	COG0488	(ABC) transporter
AS19_02670	COG0545	Peptidyl-prolyl cis-trans isomerase
AS19_02690	COG1346	cytolysis
AS19_02710	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AS19_02720	COG2918	glutathione biosynthetic process
AS19_02730	COG2183	response to ionizing radiation
AS19_02750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS19_02760	COG1566	PFAM secretion protein HlyD family protein
AS19_02770	COG0745	RESPONSE REGULATOR receiver
AS19_02780	COG2205	protein histidine kinase activity
AS19_02800	COG0569	domain protein
AS19_02810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS19_02820	COG1295	ribonuclease BN
AS19_02830	COG1252	NADH dehydrogenase
AS19_02840	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AS19_02850	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AS19_02860	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AS19_02870	COG1011	Hydrolase
AS19_02880	COG0494	nUDIX hydrolase
AS19_02890	COG1218	3'(2'),5'-bisphosphate nucleotidase
AS19_02920	COG2072	flavoprotein involved in K transport
AS19_03010	COG0488	(ABC) transporter
AS19_03040	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AS19_03060	COG0473	3-isopropylmalate dehydrogenase activity
AS19_03070	COG1131	(ABC) transporter
AS19_03080	COG0842	Transport permease protein
AS19_03090	COG3781	membrane
AS19_03100	COG3268	Saccharopine dehydrogenase
AS19_03120	COG0259	pyridoxamine-phosphate oxidase activity
AS19_03150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AS19_03160	COG0733	neurotransmitter:sodium symporter activity
AS19_03170	COG2914	Belongs to the UPF0125 (RnfH) family
AS19_03210	COG0497	DNA recombination
AS19_03230	COG1420	regulation of RNA biosynthetic process
AS19_03240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AS19_03250	COG0443	Heat shock 70 kDa protein
AS19_03260	COG0484	heat shock protein binding
AS19_03270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AS19_03280	COG0505	Belongs to the CarA family
AS19_03290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AS19_03300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AS19_03320	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AS19_03330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS19_03340	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AS19_03350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS19_03360	COG0149	triose-phosphate isomerase activity
AS19_03380	COG0779	Required for maturation of 30S ribosomal subunits
AS19_03390	COG2251	uridine kinase activity
AS19_03390	COG0195	Participates in both transcription termination and antitermination
AS19_03400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AS19_03410	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AS19_03430	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AS19_03440	COG1185	polyribonucleotide nucleotidyltransferase activity
AS19_03450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS19_03460	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AS19_03470	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AS19_03480	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AS19_03490	COG1428	Deoxynucleoside kinase
AS19_03500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AS19_03530	COG3852	Histidine kinase
AS19_03550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AS19_03560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS19_03590	COG1489	DNA binding
AS19_03600	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS19_03620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS19_03630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS19_03660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AS19_03670	COG0352	thiamine-phosphate diphosphorylase activity
AS19_03680	COG0351	phosphomethylpyrimidine kinase
AS19_03680	COG0352	thiamine-phosphate diphosphorylase activity
AS19_03680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AS19_03710	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AS19_03740	COG0316	Belongs to the HesB IscA family
AS19_03760	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AS19_03780	COG0739	heme binding
AS19_03790	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AS19_03820	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AS19_03840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AS19_03870	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AS19_03880	COG0081	regulation of translation
AS19_03890	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AS19_03900	COG0222	ribosome binding
AS19_03910	COG0085	RNA polymerase activity
AS19_03920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AS19_03930	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AS19_03940	COG0049	tRNA binding
AS19_03950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AS19_03960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AS19_03980	COG1215	transferase activity, transferring glycosyl groups
AS19_03990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AS19_04090	COG0662	Cupin 2, conserved barrel domain protein
AS19_04090	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AS19_04100	COG0051	transcription antitermination factor activity, RNA binding
AS19_04110	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AS19_04120	COG0088	Forms part of the polypeptide exit tunnel
AS19_04130	COG0089	rRNA binding
AS19_04140	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AS19_04150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AS19_04160	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AS19_04170	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AS19_04180	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AS19_04190	COG0255	Belongs to the universal ribosomal protein uL29 family
AS19_04200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AS19_04210	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AS19_04220	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AS19_04230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AS19_04240	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AS19_04250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AS19_04260	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AS19_04270	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AS19_04280	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AS19_04290	COG1841	ribosomal large subunit assembly
AS19_04300	COG0200	Binds to the 23S rRNA
AS19_04320	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AS19_04330	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AS19_04340	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AS19_04350	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AS19_04360	COG0202	RNA polymerase activity
AS19_04370	COG0203	ribosomal protein L17
AS19_04440	COG2814	Major facilitator Superfamily
AS19_04470	COG3031	protein transport across the cell outer membrane
AS19_04510	COG2267	carboxylic ester hydrolase activity
AS19_04520	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AS19_04550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS19_04590	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AS19_04660	COG0142	geranyltranstransferase activity
AS19_04670	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AS19_04680	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AS19_04690	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AS19_04700	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AS19_04710	COG0268	Binds directly to 16S ribosomal RNA
AS19_04720	COG0728	peptidoglycan biosynthetic process
AS19_04730	COG0196	riboflavin kinase activity
AS19_04740	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AS19_04760	COG1047	Peptidyl-prolyl cis-trans
AS19_04770	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AS19_04950	COG0028	Belongs to the TPP enzyme family
AS19_04990	COG0583	DNA-binding transcription factor activity
AS19_05000	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AS19_05010	COG1183	phosphatidylcholine synthase activity
AS19_05030	COG1597	lipid kinase activity
AS19_05070	COG0525	valine-tRNA ligase activity
AS19_05100	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AS19_05110	COG0795	lipopolysaccharide-transporting ATPase activity
AS19_05120	COG0795	lipopolysaccharide-transporting ATPase activity
AS19_05140	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AS19_05150	COG0343	queuine tRNA-ribosyltransferase activity
AS19_05160	COG1862	Preprotein translocase
AS19_05170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS19_05200	COG0436	Aminotransferase
AS19_05210	COG0154	amidase activity
AS19_05240	COG0473	3-isopropylmalate dehydrogenase activity
AS19_05250	COG1012	belongs to the aldehyde dehydrogenase family
AS19_05270	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AS19_05290	COG0012	GTP binding
AS19_05300	COG0193	aminoacyl-tRNA hydrolase activity
AS19_05310	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AS19_05320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AS19_05330	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AS19_05340	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AS19_05370	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AS19_05380	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AS19_05390	COG2890	protein-(glutamine-N5) methyltransferase activity
AS19_05440	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AS19_05450	COG0154	amidase activity
AS19_05460	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AS19_05470	COG1077	Cell shape determining protein MreB Mrl
AS19_05480	COG1792	Involved in formation and maintenance of cell shape
AS19_05490	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AS19_05500	COG0424	maF-like protein
AS19_05520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS19_05530	COG0312	modulator of DNA gyrase
AS19_05560	COG3028	Belongs to the UPF0307 family
AS19_05570	COG0312	modulator of DNA gyrase
AS19_05580	COG2239	Acts as a magnesium transporter
AS19_05600	COG2181	nitrate reductase activity
AS19_05610	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AS19_05620	COG1140	nitrate reductase beta subunit
AS19_05630	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AS19_05640	COG2223	nitrite transmembrane transporter activity
AS19_05650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS19_05660	COG1660	Displays ATPase and GTPase activities
AS19_05690	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AS19_05700	COG1137	ATPase activity
AS19_05730	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AS19_05770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS19_05780	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AS19_05790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AS19_05800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS19_05820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS19_05830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AS19_05840	COG1597	lipid kinase activity
AS19_05850	COG2046	Belongs to the sulfate adenylyltransferase family
AS19_05870	COG2945	thiolester hydrolase activity
AS19_05880	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AS19_05890	COG1960	acyl-CoA dehydrogenase activity
AS19_05920	COG0667	Aldo Keto reductase
AS19_05930	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AS19_05940	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AS19_05950	COG0723	plastoquinol--plastocyanin reductase activity
AS19_05960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS19_05970	COG2857	Cytochrome c1
AS19_05980	COG0625	glutathione transferase activity
AS19_05990	COG2969	positive regulation of protein catabolic process
AS19_06000	COG2823	Periplasmic or secreted lipoprotein
AS19_06020	COG0792	nuclease activity
AS19_06030	COG3107	peptidoglycan biosynthetic process
AS19_06050	COG0426	domain, Protein
AS19_06050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS19_06060	COG2001	Belongs to the MraZ family
AS19_06070	COG0275	rRNA processing
AS19_06100	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AS19_06110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AS19_06120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS19_06130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AS19_06140	COG0772	Belongs to the SEDS family
AS19_06150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AS19_06160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AS19_06170	COG1181	Belongs to the D-alanine--D-alanine ligase family
AS19_06180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AS19_06210	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AS19_06230	COG0739	heme binding
AS19_06240	COG0653	protein targeting
AS19_06260	COG0494	nUDIX hydrolase
AS19_06270	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AS19_06280	COG0237	dephospho-CoA kinase activity
AS19_06290	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AS19_06320	COG4969	Belongs to the N-Me-Phe pilin family
AS19_06350	COG1115	amino acid carrier protein
AS19_06400	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS19_06420	COG0745	RESPONSE REGULATOR receiver
AS19_06430	COG2205	protein histidine kinase activity
AS19_06440	COG2096	Adenosyltransferase
AS19_06450	COG4206	TonB-dependent receptor
AS19_06460	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS19_06480	COG2211	Major facilitator Superfamily
AS19_06500	COG1028	Short-chain dehydrogenase reductase Sdr
AS19_06510	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AS19_06520	COG0459	protein refolding
AS19_06550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS19_06600	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AS19_06610	COG2315	Protein conserved in bacteria
AS19_06650	COG0183	Belongs to the thiolase family
AS19_06710	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AS19_06720	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AS19_06740	COG1611	Belongs to the LOG family
AS19_06760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS19_06770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS19_06780	COG2226	methyltransferase
AS19_06790	COG1733	regulation of RNA biosynthetic process
AS19_06800	COG1028	Short-chain dehydrogenase reductase Sdr
AS19_06880	COG0543	2 iron, 2 sulfur cluster binding
AS19_06880	COG0633	Ferredoxin
AS19_06930	COG1309	transcriptional regulator
AS19_06940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS19_06960	COG2755	lipolytic protein G-D-S-L family
AS19_06960	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AS19_06990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AS19_07030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AS19_07050	COG0705	Rhomboid family
AS19_07140	COG1451	nucleotide metabolic process
AS19_07230	COG1012	belongs to the aldehyde dehydrogenase family
AS19_07280	COG0450	alkyl hydroperoxide reductase
AS19_07310	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS19_07330	COG0745	RESPONSE REGULATOR receiver
AS19_07340	COG2205	protein histidine kinase activity
AS19_07350	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS19_07370	COG0745	RESPONSE REGULATOR receiver
AS19_07370	COG3706	GGDEF domain
AS19_07380	COG3842	ATPase activity
AS19_07390	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AS19_07400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS19_07430	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AS19_07440	COG0450	alkyl hydroperoxide reductase
AS19_07450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AS19_07460	COG0137	argininosuccinate synthase activity
AS19_07480	COG0346	lactoylglutathione lyase activity
AS19_07490	COG4067	protein conserved in archaea
AS19_07490	COG0189	ligase activity
AS19_07500	COG0189	ligase activity
AS19_07520	COG2046	Belongs to the sulfate adenylyltransferase family
AS19_07570	COG0513	Belongs to the DEAD box helicase family
AS19_07600	COG1192	Involved in chromosome partitioning
AS19_07620	COG0442	prolyl-tRNA aminoacylation
AS19_07650	COG0729	surface antigen
AS19_07660	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AS19_07680	COG2226	methyltransferase
AS19_07730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AS19_07750	COG0217	transcriptional regulatory protein
AS19_07760	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AS19_07770	COG0632	four-way junction helicase activity
AS19_07780	COG2255	four-way junction helicase activity
AS19_07790	COG0824	Thioesterase
AS19_07830	COG0823	Involved in the tonB-independent uptake of proteins
AS19_07860	COG0602	queuosine metabolic process
AS19_07870	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AS19_07910	COG0789	Transcriptional regulator
AS19_07930	COG2267	carboxylic ester hydrolase activity
AS19_08050	COG2204	response regulator
AS19_08070	COG2801	Transposase and inactivated derivatives
AS19_08120	COG0789	Transcriptional regulator
AS19_08130	COG0415	Belongs to the DNA photolyase family
AS19_08160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AS19_08170	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AS19_08180	COG4783	chaperone-mediated protein folding
AS19_08190	COG0425	Belongs to the sulfur carrier protein TusA family
AS19_08210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS19_08220	COG2716	regulation of RNA biosynthetic process
AS19_08230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS19_08250	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AS19_08260	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AS19_08310	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AS19_08320	COG0047	phosphoribosylformylglycinamidine synthase activity
AS19_08320	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS19_08340	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AS19_08350	COG2816	NAD+ diphosphatase activity
AS19_08360	COG2197	response regulator
AS19_08380	COG0494	nUDIX hydrolase
AS19_08410	COG1752	Esterase of the alpha-beta hydrolase superfamily
AS19_08420	COG4536	flavin adenine dinucleotide binding
AS19_08440	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AS19_08450	COG0228	four-way junction DNA binding
AS19_08460	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AS19_08470	COG0336	Belongs to the RNA methyltransferase TrmD family
AS19_08480	COG0335	large ribosomal subunit rRNA binding
AS19_08490	COG2261	transglycosylase associated protein
AS19_08510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AS19_08520	COG0436	Aminotransferase
AS19_08540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AS19_08550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS19_08600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS19_08610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS19_08630	COG2264	protein methyltransferase activity
AS19_08640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS19_08690	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AS19_08700	COG0590	tRNA wobble adenosine to inosine editing
AS19_08720	COG5001	Diguanylate cyclase
AS19_08780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AS19_08790	COG0642	Histidine kinase
AS19_08820	COG4977	sequence-specific DNA binding
AS19_08830	COG1960	acyl-CoA dehydrogenase activity
AS19_08850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AS19_08870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS19_08880	COG4235	cytochrome complex assembly
AS19_08880	COG3088	subunit of a heme lyase
AS19_08900	COG0563	adenylate kinase activity
AS19_08950	COG5016	pyruvate
AS19_08950	COG0511	ligase activity, forming carbon-carbon bonds
AS19_09010	COG0477	Major facilitator Superfamily
AS19_09020	COG1116	anion transmembrane transporter activity
AS19_09020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS19_09030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS19_09040	COG1116	anion transmembrane transporter activity
AS19_09060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS19_09100	COG3707	response regulator
AS19_09110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS19_09110	COG1116	anion transmembrane transporter activity
AS19_09120	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AS19_09130	COG0583	DNA-binding transcription factor activity
AS19_09140	COG4807	Protein conserved in bacteria
AS19_09200	COG4133	protoheme IX ABC transporter activity
AS19_09240	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AS19_09250	COG0189	ligase activity
AS19_09260	COG0625	glutathione transferase activity
AS19_09280	COG1131	(ABC) transporter
AS19_09290	COG0842	Transport permease protein
AS19_09300	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AS19_09300	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AS19_09310	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AS19_09450	COG0778	Nitroreductase
AS19_09560	COG0438	transferase activity, transferring glycosyl groups
AS19_09580	COG2373	Large extracellular alpha-helical protein
AS19_09590	COG1943	Transposase
AS19_09600	COG4953	penicillin-binding protein 1C
AS19_09610	COG3383	formate dehydrogenase (NAD+) activity
AS19_09660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS19_09680	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AS19_09700	COG1088	dTDP-glucose 4,6-dehydratase activity
AS19_09710	COG1091	dTDP-4-dehydrorhamnose reductase activity
AS19_09780	COG0438	transferase activity, transferring glycosyl groups
AS19_09800	COG0438	transferase activity, transferring glycosyl groups
AS19_09820	COG0438	transferase activity, transferring glycosyl groups
AS19_09840	COG0438	transferase activity, transferring glycosyl groups
AS19_09850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AS19_09880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS19_09910	COG0471	metal ion transport
AS19_09910	COG3273	potassium ion transport
AS19_09920	COG0529	Catalyzes the synthesis of activated sulfate
AS19_09930	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AS19_09960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS19_09980	COG0166	Belongs to the GPI family
AS19_10000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AS19_10030	COG1215	transferase activity, transferring glycosyl groups
AS19_10050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AS19_10080	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AS19_10100	COG3115	cell septum assembly
AS19_10110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AS19_10150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AS19_10160	COG1028	Short-chain dehydrogenase reductase Sdr
AS19_10190	COG1960	acyl-CoA dehydrogenase activity
AS19_10210	COG1028	Short-chain dehydrogenase reductase Sdr
AS19_10220	COG1028	Short-chain dehydrogenase reductase Sdr
AS19_10260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS19_10280	COG1309	transcriptional regulator
AS19_10290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS19_10310	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AS19_10320	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AS19_10320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS19_10340	COG0784	Response regulator, receiver
AS19_10340	COG5002	protein histidine kinase activity
AS19_10340	COG2205	protein histidine kinase activity
AS19_10360	COG4106	trans-aconitate 2-methyltransferase activity
AS19_10370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS19_10460	COG0183	Belongs to the thiolase family
AS19_10470	COG1960	acyl-CoA dehydrogenase activity
AS19_10510	COG1960	acyl-CoA dehydrogenase activity
AS19_10520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS19_10530	COG1028	Short-chain dehydrogenase reductase Sdr
AS19_10550	COG1309	transcriptional regulator
AS19_10590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS19_10600	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AS19_10620	COG2267	carboxylic ester hydrolase activity
AS19_10630	COG0308	aminopeptidase N
AS19_10690	COG3130	regulation of translation
AS19_10700	COG0116	Belongs to the methyltransferase superfamily
AS19_10700	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AS19_10740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AS19_10760	COG0589	response to stress
AS19_10820	COG1376	ErfK ybiS ycfS ynhG family protein
AS19_10830	COG1472	Belongs to the glycosyl hydrolase 3 family
AS19_10840	COG0668	transmembrane transport
AS19_10850	COG0037	tRNA processing
AS19_10850	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AS19_10870	COG1253	flavin adenine dinucleotide binding
AS19_10880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS19_10890	COG2081	HI0933 family
AS19_10930	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AS19_10940	COG1946	Acyl-CoA thioesterase
AS19_10950	COG1573	uracil-dna glycosylase
AS19_10980	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AS19_10990	COG1805	sodium ion transport
AS19_11020	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AS19_11030	COG2871	sodium ion transport
AS19_11040	COG1477	protein flavinylation
AS19_11080	COG0584	glycerophosphoryl diester phosphodiesterase
AS19_11100	COG0438	transferase activity, transferring glycosyl groups
AS19_11120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS19_11130	COG2957	Belongs to the agmatine deiminase family
AS19_11150	COG4591	ABC-type transport system involved in lipoprotein release permease component
AS19_11160	COG1136	(ABC) transporter
AS19_11190	COG0811	peptide transport
AS19_11200	COG0848	biopolymer transport protein
AS19_11210	COG1132	(ABC) transporter
AS19_11220	COG1663	tetraacyldisaccharide 4'-kinase activity
AS19_11230	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AS19_11240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS19_11250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AS19_11260	COG1530	ribonuclease E activity
AS19_11280	COG0546	phosphoglycolate phosphatase activity
AS19_11290	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AS19_11290	COG0616	signal peptide processing
AS19_11300	COG0424	maF-like protein
AS19_11310	COG1399	metal-binding, possibly nucleic acid-binding protein
AS19_11320	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AS19_11330	COG0416	fatty acid biosynthetic process
AS19_11360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS19_11370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS19_11390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AS19_11400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AS19_11430	COG0084	hydrolase, TatD family'
AS19_11440	COG1322	Protein conserved in bacteria
AS19_11470	COG1104	cysteine desulfurase activity
AS19_11500	COG0515	serine threonine protein kinase
AS19_11500	COG2815	serine threonine protein kinase
AS19_11510	COG2223	nitrite transmembrane transporter activity
AS19_11520	COG2146	nitrite reductase [NAD(P)H] activity
AS19_11520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS19_11530	COG2146	nitrite reductase [NAD(P)H] activity
AS19_11530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS19_11540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS19_11550	COG0243	molybdopterin cofactor binding
AS19_11570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS19_11580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AS19_11610	COG3153	acetyltransferase
AS19_11610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS19_11650	COG0583	DNA-binding transcription factor activity
AS19_11700	COG1028	Short-chain dehydrogenase reductase Sdr
AS19_11730	COG2308	Evidence 4 Homologs of previously reported genes of
AS19_11750	COG1305	Transglutaminase-like
AS19_11770	COG2194	sulfuric ester hydrolase activity
AS19_11850	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AS19_11860	COG2894	cell division
AS19_11870	COG0850	regulation of cytokinetic process
AS19_11880	COG1960	acyl-CoA dehydrogenase activity
AS19_11890	COG3118	belongs to the thioredoxin family
AS19_11910	COG0004	ammonium transporteR
AS19_11930	COG0746	molybdenum cofactor guanylyltransferase activity
AS19_11940	COG1199	ATP-dependent helicase activity
AS19_11950	COG1214	PFAM Peptidase M22, glycoprotease
AS19_11970	COG1968	undecaprenyl-diphosphatase activity
AS19_11980	COG0742	ribosomal rna small subunit methyltransferase
AS19_11990	COG2937	Belongs to the GPAT DAPAT family
AS19_12020	COG1012	belongs to the aldehyde dehydrogenase family
AS19_12040	COG1566	PFAM secretion protein HlyD family protein
AS19_12060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS19_12080	COG1393	Belongs to the ArsC family
AS19_12090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS19_12100	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AS19_12110	COG0024	Methionine aminopeptidase
AS19_12120	COG0052	Belongs to the universal ribosomal protein uS2 family
AS19_12130	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AS19_12140	COG0528	UMP kinase activity
AS19_12150	COG0233	cytoplasmic translational termination
AS19_12160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AS19_12170	COG0575	Belongs to the CDS family
AS19_12180	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AS19_12220	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AS19_12230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AS19_12240	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AS19_12250	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AS19_12260	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AS19_12280	COG0825	malonyl-CoA metabolic process
AS19_12290	COG0037	tRNA processing
AS19_12300	COG0514	ATP-dependent DNA helicase (RecQ)
AS19_12310	COG0504	CTP synthase activity
AS19_12320	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AS19_12330	COG0148	phosphopyruvate hydratase activity
AS19_12340	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AS19_12360	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AS19_12370	COG0585	pseudouridine synthase activity
AS19_12380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AS19_12410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS19_12440	COG1454	alcohol dehydrogenase
AS19_12450	COG0824	Thioesterase
AS19_12460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS19_12490	COG0501	Belongs to the peptidase M48B family
AS19_12500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AS19_12520	COG0436	Aminotransferase
AS19_12550	COG0672	)-iron permease
AS19_12580	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS19_12600	COG0316	Belongs to the HesB IscA family
AS19_12600	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AS19_12610	COG4783	chaperone-mediated protein folding
AS19_12620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AS19_12650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AS19_12710	COG1881	PFAM PEBP family protein
AS19_12760	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AS19_12770	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AS19_12790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AS19_12800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AS19_12810	COG0544	peptidyl-prolyl cis-trans isomerase activity
AS19_12820	COG0740	serine-type endopeptidase activity
AS19_12830	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AS19_12840	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AS19_12860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AS19_12880	COG4172	Belongs to the ABC transporter superfamily
AS19_12890	COG4239	(ABC) transporter, permease
AS19_12900	COG4174	ABC transporter (Permease)
AS19_12910	COG4166	transmembrane transport
AS19_12920	COG4166	transmembrane transport
AS19_12930	COG1388	LysM domain
AS19_12930	COG0741	lytic transglycosylase activity
AS19_12940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS19_12960	COG0328	RNA-DNA hybrid ribonuclease activity
AS19_12980	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AS19_13000	COG2816	NAD+ diphosphatase activity
AS19_13020	COG0616	signal peptide processing
AS19_13030	COG0604	alcohol dehydrogenase
AS19_13040	COG2084	Dehydrogenase
AS19_13050	COG3622	Belongs to the hyi family
AS19_13060	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AS19_13080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS19_13110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS19_13120	COG1960	acyl-CoA dehydrogenase activity
AS19_13160	COG0702	epimerase
AS19_13170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AS19_13200	COG0039	L-malate dehydrogenase activity
AS19_13240	COG0271	Belongs to the BolA IbaG family
AS19_13280	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AS19_13340	COG3706	GGDEF domain
AS19_13350	COG1960	acyl-CoA dehydrogenase activity
AS19_13360	COG1960	acyl-CoA dehydrogenase activity
AS19_13370	COG0300	oxidoreductase activity
AS19_13380	COG0037	tRNA processing
AS19_13390	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AS19_13410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AS19_13440	COG2850	peptidyl-arginine hydroxylation
AS19_13460	COG2915	High frequency lysogenization protein hflD homolog
AS19_13470	COG0482	sulfurtransferase activity
AS19_13490	COG0315	cyclic pyranopterin monophosphate synthase activity
AS19_13500	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AS19_13510	COG0314	molybdopterin synthase activity
AS19_13550	COG1278	Cold shock
AS19_13570	COG0542	response to heat
AS19_13580	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AS19_13590	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AS19_13600	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AS19_13610	COG0492	ferredoxin-NADP+ reductase activity
AS19_13620	COG1674	ftsk spoiiie
AS19_13630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AS19_13640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AS19_13650	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AS19_13660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AS19_13670	COG1648	precorrin-2 dehydrogenase activity
AS19_13670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS19_13680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AS19_13710	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AS19_13730	COG0003	Pfam Anion-transporting ATPase
AS19_13750	COG1966	Carbon starvation protein
AS19_13770	COG0322	excinuclease ABC activity
AS19_13790	COG0784	Response regulator, receiver
AS19_13790	COG5002	protein histidine kinase activity
AS19_13800	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AS19_13900	COG3156	type II secretion system protein K
AS19_13920	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AS19_13970	COG0668	transmembrane transport
AS19_13990	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AS19_14000	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AS19_14010	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AS19_14060	COG0700	Nucleoside recognition
AS19_14080	COG0598	Magnesium transport protein CorA
AS19_14110	COG3022	response to hydroperoxide
AS19_14130	COG0589	response to stress
AS19_14140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS19_14190	COG0348	domain, Protein
AS19_14200	COG2010	Cytochrome c
AS19_14230	COG3278	Belongs to the heme-copper respiratory oxidase family
AS19_14240	COG3321	synthase
AS19_14240	COG0604	alcohol dehydrogenase
AS19_14240	COG1028	Short-chain dehydrogenase reductase Sdr
AS19_14250	COG0583	DNA-binding transcription factor activity
AS19_14310	COG0542	response to heat
AS19_14340	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AS19_14360	COG0180	Tryptophanyl-tRNA synthetase
AS19_14370	COG0009	L-threonylcarbamoyladenylate synthase
AS19_14380	COG0613	PHP domain protein
AS19_14390	COG2917	probably involved in intracellular septation
AS19_14400	COG2350	Protein conserved in bacteria
AS19_14430	COG0204	Acyl-transferase
AS19_14480	COG4181	ATPase activity
AS19_14490	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AS19_14500	COG2814	Major facilitator Superfamily
AS19_14520	COG0789	Transcriptional regulator
AS19_14540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS19_14550	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AS19_14560	COG0277	FAD linked oxidase domain protein
AS19_14580	COG2885	chlorophyll binding
AS19_14590	COG2169	Transcriptional regulator
AS19_14590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS19_14600	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AS19_14660	COG3243	poly(R)-hydroxyalkanoic acid synthase
AS19_14690	COG3339	Conserved Protein
AS19_14700	COG1192	Involved in chromosome partitioning
AS19_14720	COG0069	glutamate synthase activity
AS19_14730	COG0741	lytic transglycosylase activity
AS19_14730	COG1196	nuclear chromosome segregation
AS19_14730	COG0739	heme binding
AS19_14760	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AS19_14770	COG2079	MmgE PrpD family protein
AS19_14780	COG2828	Protein conserved in bacteria
AS19_14800	COG0372	Belongs to the citrate synthase family
AS19_14810	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AS19_14820	COG1802	Transcriptional regulator
AS19_14840	COG0560	Phosphoserine phosphatase
AS19_14920	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AS19_14930	COG0235	Class ii aldolase
AS19_14940	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AS19_14950	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AS19_14960	COG2813	Specifically methylates the guanine in position
AS19_14970	COG1643	Atp-dependent helicase
AS19_15010	COG0714	Associated with various cellular activities
AS19_15050	COG1286	toxin biosynthetic process
AS19_15070	COG0285	dihydrofolate synthase activity
AS19_15080	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AS19_15090	COG0159	tryptophan synthase activity
AS19_15100	COG0133	tryptophan synthase activity
AS19_15110	COG0135	phosphoribosylanthranilate isomerase activity
AS19_15120	COG0101	tRNA pseudouridine synthase activity
AS19_15140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AS19_15160	COG0473	3-isopropylmalate dehydrogenase activity
AS19_15180	COG0066	3-isopropylmalate dehydratase activity
AS19_15190	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AS19_15220	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AS19_15230	COG2890	protein-(glutamine-N5) methyltransferase activity
AS19_15250	COG0004	ammonium transporteR
AS19_15270	COG1301	dicarboxylic acid transport
AS19_15290	COG4221	oxidoreductase activity
AS19_15360	COG0708	Exodeoxyribonuclease III
AS19_15380	COG2062	phosphohistidine phosphatase, SixA
AS19_15390	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AS19_15400	COG0326	Molecular chaperone. Has ATPase activity
AS19_15430	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AS19_15440	COG0045	succinate-CoA ligase (ADP-forming) activity
AS19_15480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AS19_15490	COG1053	succinate dehydrogenase
AS19_15500	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AS19_15510	COG2009	succinate dehydrogenase
AS19_15540	COG2084	Dehydrogenase
AS19_15600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AS19_15620	COG0589	response to stress
AS19_15630	COG0659	secondary active sulfate transmembrane transporter activity
AS19_15650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS19_15670	COG2853	Lipoprotein
AS19_15690	COG3220	belongs to the UPF0276 family
AS19_15720	COG1643	Atp-dependent helicase
AS19_15770	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AS19_15810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS19_15820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS19_15940	COG1254	Belongs to the acylphosphatase family
AS19_15950	COG1959	2 iron, 2 sulfur cluster binding
AS19_15950	COG1295	ribonuclease BN
AS19_15960	COG1393	Belongs to the ArsC family
AS19_16030	COG0714	Associated with various cellular activities
AS19_16040	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AS19_16050	COG3101	peptidyl-lysine hydroxylation
AS19_16120	COG2814	Major facilitator Superfamily
AS19_16130	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AS19_16140	COG0788	formyltetrahydrofolate deformylase activity
AS19_16180	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS19_16180	COG1024	Enoyl-CoA hydratase
AS19_16190	COG0183	Belongs to the thiolase family
AS19_16230	COG2840	Smr protein MutS2
AS19_16240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS19_16250	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AS19_16270	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AS19_16280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AS19_16310	COG0717	Belongs to the dCTP deaminase family
AS19_16320	COG0489	protein tyrosine kinase activity
AS19_16400	COG2813	Specifically methylates the guanine in position
AS19_16410	COG0741	lytic transglycosylase activity
AS19_16460	COG1309	transcriptional regulator
AS19_16520	COG2205	protein histidine kinase activity
AS19_16520	COG0784	Response regulator, receiver
AS19_16520	COG5002	protein histidine kinase activity
AS19_16530	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS19_16530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS19_16540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS19_16640	COG4657	Part of a membrane complex involved in electron transport
AS19_16650	COG2878	Part of a membrane complex involved in electron transport
AS19_16670	COG4658	electron transport chain
AS19_16680	COG4659	FMN binding
AS19_16690	COG4660	Part of a membrane complex involved in electron transport
AS19_16710	COG0786	glutamate:sodium symporter activity
AS19_16720	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AS19_16740	COG1739	Uncharacterized protein family UPF0029
AS19_16770	COG3956	TIGRFAM MazG family protein
AS19_16780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AS19_16790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AS19_16820	COG5002	protein histidine kinase activity
AS19_16820	COG0784	Response regulator, receiver
AS19_16820	COG2205	protein histidine kinase activity
AS19_16830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AS19_16850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AS19_16860	COG0571	ribonuclease III activity
AS19_16890	COG0481	GTPase activity
AS19_16900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS19_17000	COG1024	Enoyl-CoA hydratase
AS19_17000	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS19_17010	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AS19_17020	COG3226	Transcriptional regulator
AS19_17030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AS19_17060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AS19_17070	COG1024	Enoyl-CoA hydratase
AS19_17070	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS19_17080	COG0183	Belongs to the thiolase family
AS19_17160	COG0789	Transcriptional regulator
AS19_17170	COG0484	heat shock protein binding
AS19_17180	COG0318	PFAM AMP-dependent synthetase and ligase
AS19_17210	COG0210	DNA helicase
AS19_17290	COG0577	efflux transmembrane transporter activity
AS19_17290	COG1136	(ABC) transporter
AS19_17320	COG0735	belongs to the Fur family
AS19_17350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS19_17380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AS19_17390	COG0546	phosphoglycolate phosphatase activity
AS19_17410	COG0175	sulfate reduction
AS19_17430	COG4771	TonB-dependent receptor
AS19_17450	COG0745	RESPONSE REGULATOR receiver
AS19_17510	COG0513	Belongs to the DEAD box helicase family
AS19_17520	COG3360	Dodecin
AS19_17530	COG0778	Nitroreductase
AS19_17570	COG1960	acyl-CoA dehydrogenase activity
AS19_17580	COG1960	acyl-CoA dehydrogenase activity
AS19_17610	COG1902	pentaerythritol trinitrate reductase activity
AS19_17610	COG0446	pyridine nucleotide-disulphide oxidoreductase
AS19_17650	COG0745	RESPONSE REGULATOR receiver
AS19_17680	COG0183	Belongs to the thiolase family
AS19_17690	COG1028	Short-chain dehydrogenase reductase Sdr
AS19_17740	COG1309	transcriptional regulator
AS19_17760	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AS19_17770	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AS19_17780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AS19_17780	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AS19_17790	COG3639	organic phosphonate transmembrane transporter activity
AS19_17810	COG0709	Synthesizes selenophosphate from selenide and ATP
AS19_17840	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AS19_17850	COG1196	nuclear chromosome segregation
AS19_17850	COG3264	Mechanosensitive ion channel
AS19_17900	COG1901	pseudouridine methyltransferase
AS19_17960	COG0284	orotidine-5'-phosphate decarboxylase activity
AS19_17990	COG0776	regulation of translation
AS19_18010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AS19_18020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AS19_18030	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS19_18040	COG1605	Chorismate mutase
AS19_18040	COG0077	Prephenate dehydratase
AS19_18050	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AS19_18070	COG0402	S-adenosylhomocysteine deaminase activity
AS19_18080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS19_18090	COG0546	phosphoglycolate phosphatase activity
AS19_18100	COG1028	Short-chain dehydrogenase reductase Sdr
AS19_18210	COG2983	Belongs to the UPF0260 family
AS19_18220	COG3100	YcgL domain-containing protein
AS19_18230	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AS19_18240	COG0588	phosphoglycerate mutase activity
AS19_18260	COG1960	acyl-CoA dehydrogenase activity
AS19_18270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AS19_18280	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AS19_18340	COG1695	Transcriptional regulator
AS19_18370	COG2977	Belongs to the P-Pant transferase superfamily
AS19_18380	COG1819	glycosyl
AS19_18390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS19_18410	COG2801	Transposase and inactivated derivatives
AS19_18460	COG0427	acetyl-CoA hydrolase
AS19_18480	COG0523	cobalamin synthesis protein
AS19_18490	COG0418	dihydroorotase activity
AS19_18500	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AS19_18510	COG0527	aspartate kinase activity
AS19_18520	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AS19_18530	COG0730	response to heat
AS19_18540	COG2137	regulation of response to DNA damage stimulus
AS19_18550	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AS19_18560	COG1546	Belongs to the CinA family
AS19_18570	COG0217	transcriptional regulatory protein
AS19_18600	COG1021	2,3-dihydroxybenzoate-AMP ligase
AS19_18670	COG2963	transposase activity
AS19_18680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AS19_18690	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AS19_18750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS19_18760	COG1509	lysine 2,3-aminomutase activity
AS19_18770	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AS19_18780	COG1074	ATP-dependent DNA helicase activity
AS19_18790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AS19_18810	COG3784	Protein of unknown function (DUF1318)
AS19_18850	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AS19_18870	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AS19_18900	COG0732	type I restriction modification DNA specificity domain
AS19_18910	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AS19_18930	COG0537	adenosine 5'-monophosphoramidase activity
AS19_18950	COG0776	regulation of translation
AS19_18960	COG0072	phenylalanine-tRNA ligase activity
AS19_18970	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AS19_18980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AS19_18990	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AS19_19000	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AS19_19020	COG0492	ferredoxin-NADP+ reductase activity
AS19_19050	COG0842	Transport permease protein
AS19_19060	COG0842	Transport permease protein
AS19_19060	COG1129	ABC transporter
AS19_19070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AS19_19080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AS19_19080	COG0519	Catalyzes the synthesis of GMP from XMP
AS19_19090	COG3706	GGDEF domain
AS19_19090	COG2203	Gaf domain
AS19_19090	COG5001	Diguanylate cyclase
AS19_19090	COG4251	negative regulation of phosphorylation
AS19_19110	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AS19_19120	COG2814	Major facilitator Superfamily
AS19_19140	COG0519	Catalyzes the synthesis of GMP from XMP
AS19_19140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AS19_19160	COG1570	exodeoxyribonuclease VII activity
AS19_19200	COG1160	GTP binding
AS19_19210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS19_19230	COG0124	histidyl-tRNA synthetase
AS19_19240	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AS19_19250	COG1426	Protein conserved in bacteria
AS19_19270	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AS19_19280	COG0105	UTP biosynthetic process
AS19_19290	COG0719	Fe-S assembly protein
AS19_19310	COG0396	ATPase activity
AS19_19320	COG0719	Fe-S assembly protein
AS19_19330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS19_19340	COG0316	Belongs to the HesB IscA family
AS19_19360	COG2166	iron-sulfur cluster assembly
AS19_19370	COG1104	cysteine desulfurase activity
AS19_19420	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AS19_19430	COG1704	LemA family
AS19_19440	COG2827	Endonuclease containing a URI domain
AS19_19510	COG3842	ATPase activity
AS19_19530	COG3665	Urea carboxylase-associated protein
AS19_19540	COG0439	Biotin carboxylase
AS19_19570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS19_19620	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS19_19630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AS19_19680	COG1612	heme a metabolic process
AS19_19690	COG0109	protoheme IX farnesyltransferase activity
AS19_19710	COG1704	LemA family
AS19_19720	COG0501	Belongs to the peptidase M48B family
AS19_19750	COG1278	Cold shock
AS19_19760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS19_19840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS19_19850	COG3047	cAMP biosynthetic process
AS19_19870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AS19_19950	COG1999	signal sequence binding
AS19_19960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS19_19980	COG1702	phosphate starvation-inducible protein PhoH
AS19_19990	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AS19_20000	COG4535	Mg2 and Co2 transporter CorC
AS19_20030	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AS19_20070	COG3453	Protein conserved in bacteria
AS19_20070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS19_20090	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AS19_20100	COG0495	leucyl-tRNA aminoacylation
AS19_20150	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AS19_20180	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AS19_20190	COG0768	penicillin binding
AS19_20200	COG0772	Belongs to the SEDS family
AS19_20210	COG2951	lytic endotransglycosylase activity
AS19_20230	COG1686	Belongs to the peptidase S11 family
AS19_20250	COG2921	Belongs to the UPF0250 family
AS19_20270	COG0321	lipoyl(octanoyl) transferase activity
AS19_20280	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AS19_20300	COG3015	lipoprotein NlpE involved in copper resistance
AS19_20320	COG0811	peptide transport
AS19_20370	COG0163	prenyltransferase activity
AS19_20390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AS19_20400	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AS19_20450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS19_20460	COG0410	ABC transporter
AS19_20470	COG1131	(ABC) transporter
AS19_20500	COG0683	leucine binding
AS19_20510	COG2198	Histidine kinase
AS19_20510	COG0784	Response regulator, receiver
AS19_20510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS19_20510	COG2205	protein histidine kinase activity
AS19_20520	COG0745	RESPONSE REGULATOR receiver
AS19_20540	COG0205	6-phosphofructokinase activity
AS19_20550	COG2233	PERMEase
AS19_20560	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AS19_20590	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AS19_20620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AS19_20630	COG3642	lipopolysaccharide core region biosynthetic process
AS19_20650	COG0642	Histidine kinase
AS19_20660	COG0745	RESPONSE REGULATOR receiver
AS19_20700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS19_20720	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AS19_20730	COG0511	ligase activity, forming carbon-carbon bonds
AS19_20750	COG2264	protein methyltransferase activity
AS19_20790	COG0138	bifunctional purine biosynthesis protein purh
AS19_20800	COG0151	Belongs to the GarS family
AS19_20820	COG3850	Histidine kinase
AS19_20820	COG3437	response regulator, receiver
AS19_20820	COG2205	protein histidine kinase activity
AS19_20820	COG4999	Histidine kinase
AS19_20830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS19_20840	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AS19_20850	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AS19_20860	COG1765	OsmC-like protein
AS19_20880	COG0134	indole-3-glycerol-phosphate synthase activity
AS19_20890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AS19_20900	COG0512	Glutamine amidotransferase of anthranilate synthase
AS19_20950	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AS19_20980	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AS19_20990	COG1845	cytochrome c oxidase, subunit III
AS19_21000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS19_21010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AS19_21020	COG0477	Major facilitator Superfamily
AS19_21050	COG0791	NLP P60 protein
AS19_21060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AS19_21090	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AS19_21100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AS19_21110	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AS19_21120	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AS19_21130	COG2967	ApaG domain
AS19_21160	COG0617	tRNA 3'-terminal CCA addition
AS19_21200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AS19_21200	COG0302	gtp cyclohydrolase
AS19_21210	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AS19_21220	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AS19_21230	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AS19_21240	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AS19_21250	COG1610	YqeY-like protein
AS19_21280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AS19_21290	COG2801	Transposase and inactivated derivatives
AS19_21300	COG2963	transposase activity
AS19_21320	COG0443	Heat shock 70 kDa protein
AS19_21340	COG0513	Belongs to the DEAD box helicase family
AS19_21390	COG4774	siderophore transport
AS19_21430	COG4615	Cyclic peptide transporter
AS19_21460	COG1960	acyl-CoA dehydrogenase activity
AS19_21470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS19_21480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS19_21490	COG2832	Protein of unknown function (DUF454)
AS19_21500	COG1960	acyl-CoA dehydrogenase activity
AS19_21510	COG2835	tetraacyldisaccharide 4'-kinase activity
AS19_21570	COG4221	oxidoreductase activity
AS19_21600	COG0300	oxidoreductase activity
AS19_21630	COG0537	adenosine 5'-monophosphoramidase activity
AS19_21670	COG5001	Diguanylate cyclase
AS19_21670	COG3706	GGDEF domain
AS19_21670	COG2203	Gaf domain
AS19_21670	COG4251	negative regulation of phosphorylation
AS19_21680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS19_21680	COG1017	nitric oxide dioxygenase activity
AS19_21690	COG1959	2 iron, 2 sulfur cluster binding
AS19_21720	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AS19_21780	COG2070	2-Nitropropane dioxygenase
AS19_21800	COG3189	MarR family transcriptional regulator
AS19_21820	COG3437	response regulator, receiver
AS19_21840	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AS19_21850	COG0215	cysteine-tRNA ligase activity
AS19_21940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS19_21970	COG1469	GTP cyclohydrolase I activity
AS19_21990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AS19_22000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AS19_22010	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AS19_22040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS19_22050	COG0662	Cupin 2, conserved barrel domain protein
AS19_22080	COG2205	protein histidine kinase activity
AS19_22080	COG0784	Response regulator, receiver
AS19_22120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS19_22180	COG1722	exodeoxyribonuclease VII activity
AS19_22190	COG0142	geranyltranstransferase activity
AS19_22200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AS19_22210	COG5001	Diguanylate cyclase
AS19_22210	COG3706	GGDEF domain
AS19_22210	COG4251	negative regulation of phosphorylation
AS19_22210	COG2203	Gaf domain
AS19_22220	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AS19_22230	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AS19_22240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AS19_22250	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AS19_22280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS19_22280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS19_22290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AS19_22300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AS19_22310	COG0488	(ABC) transporter
AS19_22330	COG1595	DNA-templated transcription, initiation
AS19_22360	COG2226	methyltransferase
AS19_22400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AS19_22410	COG0305	Participates in initiation and elongation during chromosome replication
AS19_22420	COG0359	binds to the 23S rRNA
AS19_22430	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AS19_22450	COG0360	Binds together with S18 to 16S ribosomal RNA
AS19_22460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS19_22470	COG0557	exoribonuclease II activity
AS19_22510	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AS19_22520	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AS19_22540	COG0330	HflC and HflK could
AS19_22550	COG0330	HflC and HflK could
AS19_22560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AS19_22570	COG1923	regulation of RNA biosynthetic process
AS19_22580	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AS19_22590	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AS19_22600	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS19_22610	COG0802	atpase or kinase
AS19_22620	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AS19_22620	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AS19_22640	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AS19_22650	COG1162	GTPase activity
AS19_22680	COG0688	phosphatidylethanolamine metabolic process
AS19_22710	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AS19_22720	COG2226	methyltransferase
AS19_22730	COG2267	carboxylic ester hydrolase activity
AS19_22740	COG0156	8-amino-7-oxononanoate synthase activity
AS19_22750	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AS19_22760	COG1040	competence protein
AS19_22800	COG2154	pterin-4-alpha-carbinolamine dehydratase
AS19_22820	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AS19_22830	COG0493	'glutamate synthase
AS19_22840	COG0067	glutamate synthase
AS19_22840	COG0069	glutamate synthase activity
AS19_22840	COG0070	glutamate synthase
AS19_22860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AS19_22870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AS19_22940	COG0281	malic enzyme
AS19_22950	COG0254	rRNA binding
AS19_22960	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AS19_22970	COG0018	arginyl-trna synthetase
AS19_22990	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AS19_23000	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AS19_23020	COG2226	methyltransferase
AS19_23040	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AS19_23050	COG0140	phosphoribosyl-ATP diphosphatase activity
AS19_23060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS19_23070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS19_23120	COG1490	D-aminoacyl-tRNA deacylase activity
AS19_23150	COG2204	response regulator
AS19_23160	COG3852	Histidine kinase
AS19_23200	COG0482	sulfurtransferase activity
AS19_23210	COG3083	sulfuric ester hydrolase activity
AS19_23270	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AS19_23280	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AS19_23300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS19_23310	COG4942	peptidase
AS19_23320	COG0793	Belongs to the peptidase S41A family
AS19_23330	COG2861	carbohydrate metabolic process
AS19_23340	COG0107	imidazoleglycerol-phosphate synthase activity
AS19_23350	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AS19_23370	COG0131	Imidazoleglycerol-phosphate dehydratase
AS19_23390	COG2205	protein histidine kinase activity
AS19_23410	COG1194	a g-specific adenine glycosylase
AS19_23420	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AS19_23500	COG0582	viral genome integration into host DNA
AS19_23520	COG0501	Belongs to the peptidase M48B family
AS19_23530	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AS19_23530	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AS19_23550	COG1560	Kdo2-lipid A biosynthetic process
AS19_23580	COG1215	transferase activity, transferring glycosyl groups
AS19_23600	COG0438	transferase activity, transferring glycosyl groups
AS19_23630	COG0859	PFAM glycosyl transferase family 9
AS19_23660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AS19_23670	COG1392	Phosphate transport regulator
AS19_23680	COG0306	phosphate transporter
AS19_23690	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AS19_23690	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AS19_23800	COG2995	paraquat-inducible protein a
AS19_23810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AS19_23810	COG3008	intermembrane lipid transfer
AS19_23840	COG2959	enzyme of heme biosynthesis
AS19_23860	COG0181	hydroxymethylbilane synthase activity
AS19_23880	COG3275	phosphorelay sensor kinase activity
AS19_23890	COG0165	Argininosuccinate lyase
AS19_23900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AS19_23920	COG0019	diaminopimelate decarboxylase activity
AS19_23950	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AS19_23960	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AS19_23980	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AS19_24000	COG3098	single-species biofilm formation
AS19_24070	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AS19_24090	COG0730	response to heat
AS19_24120	COG0494	nUDIX hydrolase
AS19_24170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AS19_24220	COG2132	Multicopper oxidase
AS19_24240	COG0288	reversible hydration of carbon dioxide
AS19_24250	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AS19_24260	COG1047	Peptidyl-prolyl cis-trans
AS19_24270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AS19_24280	COG1492	cobalamin metabolic process
AS19_24310	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AS19_24320	COG4139	cobalamin transport
AS19_24340	COG4206	TonB-dependent receptor
AS19_24360	COG1858	cytochrome C peroxidase
AS19_24390	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AS19_24400	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AS19_24430	COG2824	Alkylphosphonate utilization operon protein PhnA
AS19_24450	COG0521	Mo-molybdopterin cofactor biosynthetic process
AS19_24470	COG0668	transmembrane transport
AS19_24480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS19_24520	COG0432	Pfam Uncharacterised protein family UPF0047
AS19_24530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS19_24550	COG2072	flavoprotein involved in K transport
AS19_24590	COG1166	arginine decarboxylase activity
AS19_24630	COG0583	DNA-binding transcription factor activity
AS19_24660	COG3008	intermembrane lipid transfer
AS19_24670	COG2995	paraquat-inducible protein a
AS19_24690	COG0513	Belongs to the DEAD box helicase family
AS19_24720	COG0189	ligase activity
AS19_24720	COG4067	protein conserved in archaea
AS19_24730	COG2974	May be involved in recombination
AS19_24740	COG0656	L-ascorbic acid biosynthetic process
AS19_24750	COG0596	Alpha beta hydrolase
AS19_24760	COG4628	conserved protein (DUF2132)
AS19_24780	COG1309	transcriptional regulator
AS19_24790	COG1979	alcohol dehydrogenase
AS19_24810	COG1294	oxidase, subunit
AS19_24820	COG1271	oxidase subunit
AS19_24840	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AS19_24850	COG0625	glutathione transferase activity
AS19_24870	COG0583	DNA-binding transcription factor activity
AS19_24920	COG0450	alkyl hydroperoxide reductase
AS19_24940	COG5002	protein histidine kinase activity
AS19_24940	COG5001	Diguanylate cyclase
AS19_24940	COG3447	MASE1 domain protein
AS19_24950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS19_24980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS19_25010	COG1024	Enoyl-CoA hydratase
AS19_25030	COG3830	Belongs to the UPF0237 family
AS19_25030	COG0560	Phosphoserine phosphatase
AS19_25040	COG3706	GGDEF domain
AS19_25060	COG1509	lysine 2,3-aminomutase activity
AS19_25070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AS19_25080	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AS19_25100	COG0596	Alpha beta hydrolase
AS19_25120	COG0183	Belongs to the thiolase family
AS19_25130	COG1960	acyl-CoA dehydrogenase activity
AS19_25170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AS19_25250	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AS19_25300	COG4771	TonB-dependent receptor
AS19_25310	COG0154	amidase activity
AS19_25320	COG0604	alcohol dehydrogenase
AS19_25370	COG3122	Protein conserved in bacteria
AS19_25400	COG0204	Acyl-transferase
AS19_25430	COG3150	esterase
AS19_25440	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AS19_25450	COG3151	Protein conserved in bacteria
AS19_25460	COG0494	nUDIX hydrolase
AS19_25470	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AS19_25480	COG1538	Outer membrane efflux protein
AS19_25490	COG1519	Transferase
AS19_25510	COG0667	Aldo Keto reductase
AS19_25580	COG0559	Belongs to the binding-protein-dependent transport system permease family
AS19_25600	COG0411	ABC transporter
AS19_25610	COG0410	ABC transporter
AS19_25650	COG0784	Response regulator, receiver
AS19_25650	COG2205	protein histidine kinase activity
AS19_25670	COG4566	intracellular signal transduction
AS19_25680	COG4191	Histidine kinase
AS19_25710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AS19_25780	COG0004	ammonium transporteR
AS19_25790	COG0347	Belongs to the P(II) protein family
AS19_25800	COG2960	long-chain fatty acid transporting porin activity
AS19_25830	COG1028	Short-chain dehydrogenase reductase Sdr
AS19_25860	COG1187	pseudouridine synthase activity
AS19_25870	COG0210	DNA helicase
AS19_25940	COG2076	Multidrug Resistance protein
AS19_26060	COG1024	Enoyl-CoA hydratase
AS19_26090	COG1196	nuclear chromosome segregation
AS19_26090	COG3264	Mechanosensitive ion channel
AS19_26130	COG0742	ribosomal rna small subunit methyltransferase
AS19_26150	COG0612	Peptidase, M16
AS19_26160	COG0552	protein localization to endoplasmic reticulum
AS19_26170	COG2884	Cell division ATP-binding protein ftsE
AS19_26180	COG2177	Part of the ABC transporter FtsEX involved in
AS19_26200	COG2363	Small membrane protein
AS19_26220	COG2022	thiamine diphosphate biosynthetic process
AS19_26230	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AS19_26260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AS19_26270	COG2813	Specifically methylates the guanine in position
AS19_26270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AS19_26290	COG1671	Belongs to the UPF0178 family
AS19_26300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AS19_26310	COG1309	transcriptional regulator
AS19_26330	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS19_26380	COG1280	lysine exporter protein (LysE YggA)
AS19_26390	COG2801	Transposase and inactivated derivatives
AS19_26400	COG2801	Transposase and inactivated derivatives
AS19_26430	COG2801	Transposase and inactivated derivatives
AS19_26490	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS19_26500	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS19_26510	COG0509	glycine decarboxylation via glycine cleavage system
AS19_26520	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AS19_26540	COG1178	ABC-type Fe3 transport system permease component
AS19_26560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS19_26570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS19_26580	COG0006	proline dipeptidase activity
AS19_26590	COG3079	Belongs to the UPF0149 family
AS19_26630	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AS19_26650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AS19_26660	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AS19_26730	COG0126	phosphoglycerate kinase activity
AS19_26750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AS19_26760	COG0640	Transcriptional regulator
AS19_26770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AS19_26780	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AS19_26790	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AS19_26810	COG0469	pyruvate kinase activity
AS19_26840	COG0534	Mate efflux family protein
AS19_26870	COG3123	guanosine phosphorylase activity
AS19_26930	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AS19_26930	COG0678	peroxiredoxin activity
AS19_26940	COG0783	Belongs to the Dps family
AS19_26950	COG1272	protein, Hemolysin III
AS19_26960	COG0640	Transcriptional regulator
AS19_26990	COG0386	Belongs to the glutathione peroxidase family
AS19_27060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AS19_27090	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AS19_27110	COG1320	monovalent cation:proton antiporter activity
AS19_27120	COG2212	antiporter activity
AS19_27140	COG0651	ATP synthesis coupled electron transport
AS19_27150	COG1006	Multisubunit Na H antiporter MnhC subunit
AS19_27160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS19_27160	COG2111	Na H antiporter
AS19_27200	COG1960	acyl-CoA dehydrogenase activity
AS19_27230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS19_27240	COG5001	Diguanylate cyclase
AS19_27240	COG5002	protein histidine kinase activity
AS19_27240	COG3447	MASE1 domain protein
AS19_27300	COG2900	Belongs to the SlyX family
AS19_27310	COG2119	membrane
AS19_27320	COG4681	YaeQ
AS19_27350	COG0431	NADPH-dependent FMN reductase
AS19_27360	COG0798	PFAM Bile acid sodium symporter
AS19_27370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS19_27380	COG0640	Transcriptional regulator
AS19_27390	COG0704	Plays a role in the regulation of phosphate uptake
AS19_27400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS19_27410	COG0581	inorganic phosphate transmembrane transporter activity
AS19_27420	COG0573	inorganic phosphate transmembrane transporter activity
AS19_27460	COG1607	acyl-coa hydrolase
AS19_27470	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AS19_27480	COG0210	DNA helicase
AS19_27520	COG0668	transmembrane transport
AS19_27560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS19_27590	COG1793	dna ligase
AS19_27600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS19_27600	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS19_27610	COG2354	Protein conserved in bacteria
AS19_27630	COG2909	trisaccharide binding
AS19_27640	COG3239	Fatty acid desaturase
AS19_27650	COG1773	rubredoxin
AS19_27810	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AS19_27830	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AS19_27840	COG0830	nickel cation binding
AS19_27850	COG0830	nickel cation binding
AS19_27870	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AS19_27880	COG0804	urea catabolic process
AS19_27890	COG0832	Belongs to the urease beta subunit family
AS19_27900	COG0831	urea catabolic process
AS19_27910	COG0829	nickel cation binding
AS19_27930	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AS19_27940	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AS19_27950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AS19_27960	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AS19_27970	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AS19_27980	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AS19_27990	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AS19_28010	COG0356	it plays a direct role in the translocation of protons across the membrane
AS19_28030	COG1475	DNA binding
AS19_28040	COG1192	Involved in chromosome partitioning
AS19_28050	COG0357	Ribosomal RNA small subunit methyltransferase G
AS19_28060	COG0445	tRNA wobble uridine modification
AS19_28070	COG3263	regulation of cellular component size
AS19_28080	COG1960	acyl-CoA dehydrogenase activity
AS19_28110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS19_28120	COG0676	glucose-6-phosphate 1-epimerase activity
AS19_28130	COG1278	Cold shock
AS19_28150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS19_28170	COG0318	PFAM AMP-dependent synthetase and ligase
AS19_28190	COG1309	transcriptional regulator
AS19_28210	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AS19_28220	COG0706	membrane insertase activity
AS19_28240	COG0230	Belongs to the bacterial ribosomal protein bL34 family