locus-tag	class	description
APS56_00040	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APS56_00050	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APS56_00070	ENOG4105E9K	Isocitrate dehydrogenase
APS56_00075	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
APS56_00085	ENOG4107G87	m6 family metalloprotease domain protein
APS56_00105	ENOG4105CBC	glutamate synthase
APS56_00115	ENOG4105C4R	Atp-dependent dna helicase
APS56_00135	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
APS56_00165	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
APS56_00170	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
APS56_00180	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
APS56_00185	ENOG4107W2A	UPF0173 metal-dependent hydrolase
APS56_00190	ENOG4105DTQ	mandelate racemase muconate lactonizing
APS56_00195	ENOG4107FCW	Abortive infection protein
APS56_00210	ENOG4105NI8	Cytosine-specific methyltransferase
APS56_00215	ENOG4108V0P	LemA family
APS56_00225	ENOG4105C2C	drug resistance transporter, Bcr CflA
APS56_00245	ENOG4105C1J	atp-dependent rna helicase
APS56_00250	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
APS56_00255	ENOG4108XXK	NUDIX hydrolase
APS56_00260	ENOG4105CN9	Peptidase m42 family protein
APS56_00270	ENOG4108UT2	hemolysin iii
APS56_00290	ENOG4108D32	Methyltransferase
APS56_00320	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
APS56_00325	ENOG4105C8Y	Acetylornithine aminotransferase
APS56_00335	ENOG4105VDW	Csbd family
APS56_00365	ENOG4105BZU	Histidine kinase
APS56_00385	ENOG4108Z9K	Osmotically inducible protein
APS56_00410	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
APS56_00415	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
APS56_00430	ENOG4105IIU	Aminopeptidase
APS56_00450	ENOG4107YZX	Universal stress protein
APS56_00460	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
APS56_00480	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
APS56_00485	ENOG4105C9A	Phoh family
APS56_00500	ENOG4107QWK	SAICAR synthetase
APS56_00520	ENOG4105D2H	Uronic isomerase
APS56_00535	ENOG4105ETE	Transcriptional regulator (LacI family
APS56_00540	ENOG4105ETE	Transcriptional regulator (LacI family
APS56_00545	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
APS56_00550	ENOG4105CHR	reductase
APS56_00560	ENOG4105EIP	mannose-6-phosphate isomerase
APS56_00565	ENOG4105CV1	Transketolase (EC 2.2.1.1)
APS56_00570	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
APS56_00580	ENOG4105G6Z	alkaline phosphatase
APS56_00585	ENOG4105C27	TonB-dependent Receptor Plug
APS56_00595	ENOG4108JPW	Aminotransferase
APS56_00610	ENOG4107YZX	Universal stress protein
APS56_00620	ENOG4105BZU	Histidine kinase
APS56_00625	ENOG4105EM2	membrane
APS56_00640	ENOG4105C9F	isomerase
APS56_00645	ENOG4105DET	Rhamnulokinase
APS56_00650	ENOG4107W7X	Aldolase
APS56_00665	ENOG4105D0C	transport protein
APS56_00670	ENOG4107ENK	receptor
APS56_00690	ENOG4108JQ1	Dehydrogenase
APS56_00695	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
APS56_00705	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
APS56_00725	ENOG4105C3G	gtp-binding protein
APS56_00740	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
APS56_00750	ENOG4105DF5	DNA topoisomerase IV, subunit A
APS56_00760	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
APS56_00765	ENOG4105EYW	Ion transport protein
APS56_00780	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
APS56_00785	ENOG4105DFA	alanine racemase domain protein
APS56_00790	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
APS56_00795	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
APS56_00800	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
APS56_00810	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
APS56_00815	ENOG4107QN2	dihydrolipoyl dehydrogenase
APS56_00840	ENOG4105C1J	atp-dependent rna helicase
APS56_00860	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
APS56_00865	ENOG4105CPN	adenine deaminase
APS56_00885	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
APS56_00900	ENOG4107QZF	nitrite reductase NADPH large subunit
APS56_00915	ENOG4105BZU	Histidine kinase
APS56_00925	ENOG4107RNU	major facilitator superfamily MFS_1
APS56_00930	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
APS56_00945	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APS56_00960	ENOG4105C27	TonB-dependent Receptor Plug
APS56_01025	ENOG4105EDR	glucose galactose transporter
APS56_01035	ENOG4105BZU	Histidine kinase
APS56_01040	ENOG4108UXN	response regulator
APS56_01045	ENOG4105BZU	Histidine kinase
APS56_01060	ENOG4105E1F	short-chain dehydrogenase reductase
APS56_01070	ENOG4105C5H	ABC transporter
APS56_01130	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
APS56_01135	ENOG4106HB6	Alpha beta hydrolase
APS56_01230	ENOG4107RGJ	metallophosphoesterase
APS56_01295	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APS56_01300	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
APS56_01335	ENOG4105DY9	regulatoR
APS56_01340	ENOG4105KA0	thioesterase Superfamily protein
APS56_01345	ENOG4105E4F	Isochorismate synthase
APS56_01350	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
APS56_01360	ENOG4105QNR	S1 RNA binding domain protein
APS56_01370	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APS56_01375	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
APS56_01385	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APS56_01475	ENOG4108IJF	Heavy metal efflux pump, CzcA
APS56_01495	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
APS56_01540	ENOG4105CPP	Dehydrogenase, E1 component
APS56_01550	ENOG4108URH	decarboxylase
APS56_01555	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
APS56_01585	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
APS56_01600	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
APS56_01610	ENOG4105CAT	Cytidine monophosphate kinase
APS56_01630	ENOG4108NEV	two component transcriptional regulator, LytTR family
APS56_01635	ENOG4108HRK	Histidine kinase
APS56_01645	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
APS56_01650	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
APS56_01655	ENOG4105CXT	aspartate transcarbamylase
APS56_01665	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
APS56_01675	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
APS56_01690	ENOG4105KCK	Peptidoglycan-associated lipoprotein
APS56_01720	ENOG4105KCK	Peptidoglycan-associated lipoprotein
APS56_01745	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
APS56_01765	ENOG4105C6E	dna polymerase iii
APS56_01770	ENOG4105CA0	peroxidase
APS56_01790	ENOG4105C7H	Helicase, RecD TraA family
APS56_01800	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
APS56_01810	ENOG4107RJC	Iron-containing alcohol dehydrogenase
APS56_01830	ENOG410904A	RNA polymerase
APS56_01840	ENOG4105C87	Aminotransferase class I and II
APS56_01865	ENOG4105ER2	Ompa motb domain protein
APS56_01875	ENOG4105VCH	membrane
APS56_01880	ENOG4105CUY	Mechanosensitive ion channel
APS56_01900	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
APS56_01905	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
APS56_01915	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
APS56_01920	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
APS56_01925	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
APS56_01935	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
APS56_01940	ENOG4105CIH	Imidazole acetol-phosphate transaminase
APS56_01945	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
APS56_01950	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
APS56_01970	ENOG4107RAN	Peptidase, M16
APS56_01985	ENOG4105C27	TonB-dependent Receptor Plug
APS56_01995	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APS56_02005	ENOG4105CHR	reductase
APS56_02010	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
APS56_02015	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APS56_02020	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
APS56_02025	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APS56_02030	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APS56_02035	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APS56_02040	ENOG4105DCI	Phosphohydrolase
APS56_02045	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APS56_02050	ENOG4105K8N	protein family UPF0079, ATPase
APS56_02065	ENOG4105DCF	alanine dehydrogenase
APS56_02080	ENOG4105C5E	polysaccharide biosynthesis protein
APS56_02085	ENOG4105D49	3-dehydroquinate synthase
APS56_02095	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
APS56_02115	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
APS56_02120	ENOG4108IAJ	Nad-dependent epimerase dehydratase
APS56_02125	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
APS56_02130	ENOG4107QQG	Dehydrogenase
APS56_02145	ENOG4105K64	Glycosyl transferase, family 2
APS56_02160	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
APS56_02175	ENOG4108SHN	Glycosyl transferase, family 2
APS56_02185	ENOG4105K64	Glycosyl transferase, family 2
APS56_02190	ENOG4108KMV	Glycosyl transferase (Group 1
APS56_02215	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
APS56_02225	ENOG4105D3Q	Sugar transferase
APS56_02230	ENOG4105D3Q	Sugar transferase
APS56_02250	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
APS56_02255	ENOG4108VVK	transcriptional Regulator, AsnC
APS56_02280	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
APS56_02290	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APS56_02295	ENOG4105CSM	endonuclease III
APS56_02305	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
APS56_02310	ENOG4105C26	Dehydrogenase
APS56_02320	ENOG4105C98	muts2 protein
APS56_02330	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
APS56_02335	ENOG4105KHC	sulfurtransferase
APS56_02345	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
APS56_02360	ENOG4105KPY	Small multidrug resistance protein
APS56_02365	ENOG4105CQB	FAD linked oxidase domain protein
APS56_02380	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
APS56_02390	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
APS56_02395	ENOG4105C34	Pseudouridine synthase
APS56_02400	ENOG4105DFD	Na H antiporter
APS56_02405	ENOG4105D3R	alkyl hydroperoxide reductase
APS56_02410	ENOG41080RH	Thioredoxin
APS56_02420	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
APS56_02425	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
APS56_02440	ENOG4105CNU	cell division protein FtsK
APS56_02455	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
APS56_02460	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
APS56_02480	ENOG4105ID8	Transcriptional regulator, ARAC family
APS56_02565	ENOG41082BM	Transcriptional regulator, arsr family
APS56_02590	ENOG4105CZ9	Domain of unknown function (DU1801)
APS56_02625	ENOG4105NAE	bifunctional deaminase-reductase domain protein
APS56_02645	ENOG4108UW5	maltose o-acetyltransferase
APS56_02660	ENOG4105EXW	epimerase dehydratase
APS56_02670	ENOG4105F2W	methyltransferase
APS56_02680	ENOG4105EU0	Major facilitator Superfamily
APS56_02695	ENOG4105DKW	ABC transporter
APS56_02700	ENOG4105EU0	Major facilitator Superfamily
APS56_02795	ENOG4107R3N	Filamentation induced by cAMP protein fic
APS56_02820	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
APS56_02840	ENOG4105EUB	pirin domain protein
APS56_02855	ENOG4105CHR	reductase
APS56_02860	ENOG4105DKW	ABC transporter
APS56_02875	ENOG4105CTQ	phosphohexokinase
APS56_02885	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
APS56_02890	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
APS56_02920	ENOG4105CWX	Alpha-1,2-mannosidase
APS56_02925	ENOG4107SYN	Glycosyl hydrolases family 43
APS56_02930	ENOG4105E2D	ec 3.2.1.52
APS56_02955	ENOG4105CWX	Alpha-1,2-mannosidase
APS56_02960	ENOG4105CBG	Sulfatase
APS56_02965	ENOG4105E2D	ec 3.2.1.52
APS56_02980	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
APS56_02985	ENOG41061MV	Arylsulfatase
APS56_02990	ENOG41061MV	Arylsulfatase
APS56_03000	ENOG4105CBG	Sulfatase
APS56_03005	ENOG41061MV	Arylsulfatase
APS56_03010	ENOG4105CBG	Sulfatase
APS56_03030	ENOG4105CBG	Sulfatase
APS56_03035	ENOG4105CBG	Sulfatase
APS56_03050	ENOG4105CWX	Alpha-1,2-mannosidase
APS56_03055	ENOG4105E2D	ec 3.2.1.52
APS56_03075	ENOG4105CKB	glycosidase
APS56_03085	ENOG4105CWX	Alpha-1,2-mannosidase
APS56_03095	ENOG4105DY9	regulatoR
APS56_03100	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
APS56_03105	ENOG4105C27	TonB-dependent Receptor Plug
APS56_03115	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
APS56_03135	ENOG4105FJR	Lmbe family
APS56_03140	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
APS56_03145	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
APS56_03155	ENOG4107VIJ	nudix hydrolase
APS56_03165	ENOG4105C5H	ABC transporter
APS56_03185	ENOG4107QX3	carboxylase
APS56_03205	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
APS56_03210	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
APS56_03215	ENOG4105NAU	thioesterase Superfamily protein
APS56_03245	ENOG4105CTJ	Metal Dependent Phosphohydrolase
APS56_03250	ENOG4105CHU	acetyl-coa acetyltransferase
APS56_03255	ENOG4107SN7	NLP P60 protein
APS56_03265	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APS56_03275	ENOG4105DEU	major facilitator superfamily
APS56_03285	ENOG4105E0X	reductase
APS56_03295	ENOG4107QN2	dihydrolipoyl dehydrogenase
APS56_03305	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
APS56_03310	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APS56_03315	ENOG4105BZU	Histidine kinase
APS56_03320	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
APS56_03345	ENOG4107QI6	Cysteine desulfurase
APS56_03380	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
APS56_03385	ENOG4107QN1	sodium solute
APS56_03400	ENOG4108UHE	carbonic anhydrase
APS56_03405	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
APS56_03410	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
APS56_03415	ENOG4105Y7M	Transcriptional regulator, TetR family
APS56_03430	ENOG4108I6A	alcohol dehydrogenase
APS56_03440	ENOG4105C72	UPF0176 protein
APS56_03455	ENOG4105K63	Thioredoxin
APS56_03460	ENOG4105C4M	(Ubiquinol oxidase) subunit I
APS56_03465	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
APS56_03480	ENOG4105D7K	pfkb domain protein
APS56_03495	ENOG4105DWY	Agmatine deiminase
APS56_03500	ENOG4105ES4	Nitrilase
APS56_03520	ENOG4105VEQ	Cold shock protein
APS56_03530	ENOG4105CPC	Aldo Keto reductase
APS56_03560	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
APS56_03570	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
APS56_03575	ENOG4105CFH	Aspartokinase
APS56_03580	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
APS56_03585	ENOG4105D98	threonine synthase
APS56_03590	ENOG4105BZU	Histidine kinase
APS56_03595	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
APS56_03600	ENOG4105CSV	Glutaminase
APS56_03610	ENOG4105KZX	Pterin carbinolamine dehydratase
APS56_03615	ENOG4105CDY	transcriptional regulatory protein
APS56_03625	ENOG4105CPK	Glycosyl transferase (Group 1
APS56_03630	ENOG4105D17	glycoside hydrolase, family 3 domain protein
APS56_03640	ENOG4105DF6	Fe-S oxidoreductase
APS56_03645	ENOG4105DF6	Fe-S oxidoreductase
APS56_03650	ENOG4107KIA	Virulence factor Mce family protein
APS56_03655	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
APS56_03670	ENOG4105BZU	Histidine kinase
APS56_03675	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
APS56_03690	ENOG4105NPQ	Pfam:DUF403
APS56_03700	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
APS56_03715	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APS56_03730	ENOG4105P4J	Allophanate hydrolase, subunit 1
APS56_03735	ENOG4105E7W	lamb ycsf family protein
APS56_03745	ENOG4105C0P	Mg chelatase subunit ChlI
APS56_03755	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
APS56_03760	ENOG4105F4R	Transcriptional regulator mode
APS56_03770	ENOG41080H2	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
APS56_03780	ENOG4105D06	uba thif-type nad fad binding protein
APS56_03790	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APS56_03795	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APS56_03800	ENOG4105EP8	Glycosyl Hydrolase Family 88
APS56_03805	ENOG41080HT	Transcriptional regulator, arsr family
APS56_03820	ENOG4105D6J	arsenicaL-resistance protein
APS56_03830	ENOG4105EUJ	GTP cyclohydrolase i
APS56_03855	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
APS56_03860	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
APS56_03865	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
APS56_03870	ENOG4108NEV	two component transcriptional regulator, LytTR family
APS56_03875	ENOG4105C25	Primosomal protein n'
APS56_03895	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
APS56_03900	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
APS56_03910	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
APS56_03915	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
APS56_03920	ENOG4105I3K	Ferric uptake regulator, Fur family
APS56_03925	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
APS56_03940	ENOG4105C27	TonB-dependent Receptor Plug
APS56_03955	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
APS56_03965	ENOG4105C8Y	Acetylornithine aminotransferase
APS56_03985	ENOG4105E2X	shikimate dehydrogenase
APS56_03995	ENOG410667J	hydrolase
APS56_04000	ENOG4105DXN	mazG family
APS56_04005	ENOG410667J	hydrolase
APS56_04010	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
APS56_04020	ENOG4105CDU	Replicative dna helicase
APS56_04025	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
APS56_04040	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
APS56_04055	ENOG4105VEJ	Heat shock protein
APS56_04060	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
APS56_04065	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
APS56_04130	ENOG4105EWK	phytoene
APS56_04150	ENOG4105C5I	Dehydrogenase
APS56_04155	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APS56_04165	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
APS56_04170	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
APS56_04190	ENOG4106WTF	Glycosyl transferase, family 2
APS56_04195	ENOG4107T8Q	Glycosyl transferase (Group 1
APS56_04210	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
APS56_04215	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APS56_04220	ENOG4107SF2	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
APS56_04250	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
APS56_04270	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
APS56_04275	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
APS56_04300	ENOG4105CSR	polyphosphate kinase 2
APS56_04305	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APS56_04310	ENOG4105EGS	Mechanosensitive ion channel
APS56_04315	ENOG4105RHA	ABC transporter, permease
APS56_04320	ENOG4108IUX	(ABC) transporter
APS56_04325	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
APS56_04330	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APS56_04365	ENOG4107QI1	Mate efflux family protein
APS56_04370	ENOG4105EA8	2-Nitropropane dioxygenase
APS56_04380	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
APS56_04395	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APS56_04400	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
APS56_04405	ENOG4105VRT	cytoplasmic protein
APS56_04415	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APS56_04420	ENOG4105DY8	decarboxylase
APS56_04425	ENOG41074B2	UPF0747 protein
APS56_04435	ENOG4108RPX	mosc domain containing protein
APS56_04455	ENOG4105CM2	brancheD-chain amino acid aminotransferase
APS56_04475	ENOG41083GQ	Protein CrcB homolog
APS56_04510	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
APS56_04515	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
APS56_04520	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
APS56_04530	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
APS56_04540	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
APS56_04545	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
APS56_04550	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
APS56_04555	ENOG4105CBG	Sulfatase
APS56_04580	ENOG4105C27	TonB-dependent Receptor Plug
APS56_04595	ENOG41061MV	Arylsulfatase
APS56_04600	ENOG41061MV	Arylsulfatase
APS56_04615	ENOG41061MV	Arylsulfatase
APS56_04625	ENOG4105CBG	Sulfatase
APS56_04655	ENOG4105C27	TonB-dependent Receptor Plug
APS56_04735	ENOG4105W5Q	DNA repair protein (RadC
APS56_04740	ENOG4108UUM	single-stranded DNA-binding protein
APS56_04805	ENOG4105C27	TonB-dependent Receptor Plug
APS56_04815	ENOG4107RJ1	sodium solute
APS56_04870	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APS56_04925	ENOG4107TPS	domain protein
APS56_04935	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
APS56_04945	ENOG4105CP7	Triose-phosphate isomerase
APS56_04950	ENOG4107ZT5	Thiol disulfide interchange protein
APS56_04955	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
APS56_04970	ENOG4105EEI	dihydropteroate synthase
APS56_04980	ENOG4105C8B	TIGR00159 family
APS56_04985	ENOG4105BZ1	(ABC) transporter
APS56_04990	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
APS56_05005	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
APS56_05015	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
APS56_05025	ENOG4105CUT	histidyl-tRNA synthetase
APS56_05030	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
APS56_05035	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
APS56_05060	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
APS56_05075	ENOG4107R5B	glutamine synthetase
APS56_05080	ENOG4108AEY	RNA polymerase sigma factor
APS56_05115	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
APS56_05120	ENOG4105II7	pyrroline-5-carboxylate reductase
APS56_05135	ENOG4105VIE	preprotein translocase, subunit YajC
APS56_05145	ENOG4107R6T	Involved in the transcription termination process (By similarity)
APS56_05150	ENOG4105BZ1	(ABC) transporter
APS56_05160	ENOG4108Z7R	Chaperone CsaA
APS56_05170	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
APS56_05175	ENOG4105C9U	ATP-dependent DNA helicase RecQ
APS56_05180	ENOG4105C2X	Arabinose 5-phosphate isomerase
APS56_05185	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
APS56_05190	ENOG4108IUZ	ABC transporter
APS56_05205	ENOG4105CKW	Inner membrane protein yedI
APS56_05230	ENOG4107RA4	Glycosyl transferase (Group 1
APS56_05255	ENOG4105JEU	Glycosyl transferase, family 2
APS56_05275	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
APS56_05280	ENOG4105D2T	synthase
APS56_05285	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
APS56_05325	ENOG4105K64	Glycosyl transferase, family 2
APS56_05330	ENOG4107T8Q	Glycosyl transferase (Group 1
APS56_05340	ENOG4105K64	Glycosyl transferase, family 2
APS56_05345	ENOG4105K64	Glycosyl transferase, family 2
APS56_05355	ENOG4107T8Q	Glycosyl transferase (Group 1
APS56_05360	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
APS56_05370	ENOG4108UW5	maltose o-acetyltransferase
APS56_05395	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
APS56_05400	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
APS56_05405	ENOG4107YJ4	chain length determinant protein
APS56_05415	ENOG4105C5H	ABC transporter
APS56_05425	ENOG4105CDV	Ompa motb domain protein
APS56_05440	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
APS56_05475	ENOG4105C1J	atp-dependent rna helicase
APS56_05510	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
APS56_05515	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
APS56_05525	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APS56_05530	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APS56_05535	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
APS56_05540	ENOG4107VNI	ribosomal protein l10
APS56_05545	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
APS56_05550	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
APS56_05570	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
APS56_05595	ENOG4105MS2	ribosomal subunit Interface protein
APS56_05600	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APS56_05605	ENOG41083X6	30S ribosomal protein S21
APS56_05615	ENOG4105C1G	acyl-Coa dehydrogenase
APS56_05625	ENOG4105BZG	amino acid carrier protein
APS56_05630	ENOG4107SVH	Potassium channel protein
APS56_05645	ENOG4105CBG	Sulfatase
APS56_05655	ENOG4105DGW	oligopeptidase A
APS56_05660	ENOG4105VN1	Heat shock protein
APS56_05700	ENOG4105EHZ	conserved protein UCP016719
APS56_05715	ENOG4108XC3	NADH ubiquinone oxidoreductase
APS56_05730	ENOG4105CAK	Cell division ATP-binding protein ftsE
APS56_05740	ENOG4105K64	Glycosyl transferase, family 2
APS56_05785	ENOG4105CI3	gtp-binding protein typa
APS56_05795	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
APS56_05815	ENOG4108W6C	Dehydrogenase
APS56_05820	ENOG4108IUK	alpha amylase, catalytic
APS56_05880	ENOG4105EDR	glucose galactose transporter
APS56_05885	ENOG4105CHR	reductase
APS56_05895	ENOG4105ERH	Fumarylacetoacetate hydrolase
APS56_05905	ENOG4105CTX	dehydratase
APS56_05915	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
APS56_05940	ENOG4106KS4	Sulfatase
APS56_05950	ENOG41061MV	Arylsulfatase
APS56_05960	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
APS56_05970	ENOG4105F2F	Xylan 1,4-beta-xylosidase (EC 3.2.1.37)
APS56_06010	ENOG4105CBG	Sulfatase
APS56_06025	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
APS56_06090	ENOG4105CBG	Sulfatase
APS56_06115	ENOG41061MV	Arylsulfatase
APS56_06120	ENOG4105C4W	S-formylglutathione hydrolase
APS56_06175	ENOG4105C27	TonB-dependent Receptor Plug
APS56_06195	ENOG4105D3Q	Sugar transferase
APS56_06205	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
APS56_06210	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
APS56_06215	ENOG4107QR9	Iron-sulfur cluster binding protein
APS56_06220	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
APS56_06245	ENOG4105C27	TonB-dependent Receptor Plug
APS56_06285	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APS56_06290	ENOG4105D82	Glutamate dehydrogenase
APS56_06295	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
APS56_06325	ENOG4105CAH	Chromate
APS56_06340	ENOG4105C27	TonB-dependent Receptor Plug
APS56_06355	ENOG4105ETE	Transcriptional regulator (LacI family
APS56_06380	ENOG4108K0D	peptidase, M48
APS56_06390	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
APS56_06410	ENOG4105M08	Membrane
APS56_06415	ENOG4105CJ2	(LipO)protein
APS56_06435	ENOG4108UJV	acyl-CoA thioesterase i
APS56_06440	ENOG4108I0Y	(ABC) transporter
APS56_06460	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APS56_06465	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APS56_06470	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APS56_06475	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APS56_06490	ENOG4105NWN	ApaG protein
APS56_06510	ENOG4105DFU	Cell wall formation (By similarity)
APS56_06520	ENOG4107S85	alpha-2-macroglobulin domain protein
APS56_06545	ENOG4105EYW	Ion transport protein
APS56_06550	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APS56_06555	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
APS56_06560	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
APS56_06565	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
APS56_06570	ENOG4105DGW	oligopeptidase A
APS56_06590	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APS56_06595	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
APS56_06655	ENOG4105CBG	Sulfatase
APS56_06665	ENOG4108SHN	Glycosyl transferase, family 2
APS56_06670	ENOG4107R8N	Glycosyl transferase, family 2
APS56_06690	ENOG4105DHJ	ABC, transporter
APS56_06700	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
APS56_06715	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
APS56_06720	ENOG4105EMU	Dehydrogenase
APS56_06730	ENOG4105C7S	Dehydrogenase
APS56_06740	ENOG4105KG3	cytidine deaminase
APS56_06760	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
APS56_06790	ENOG4105NAE	bifunctional deaminase-reductase domain protein
APS56_06810	ENOG4105CZ9	Domain of unknown function (DU1801)
APS56_06840	ENOG41082BM	Transcriptional regulator, arsr family
APS56_06930	ENOG41082BM	Transcriptional regulator, arsr family
APS56_06940	ENOG4108ZX5	transcriptional regulator
APS56_06975	ENOG4105JD4	ATPase yjob
APS56_07005	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
APS56_07085	ENOG4105W5Q	DNA repair protein (RadC
APS56_07090	ENOG4108UUM	single-stranded DNA-binding protein
APS56_07160	ENOG4105C5H	ABC transporter
APS56_07190	ENOG4105E6M	Sulphatase-modifying factor protein
APS56_07200	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
APS56_07210	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
APS56_07215	ENOG4108JUA	Transcriptional regulator
APS56_07235	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
APS56_07240	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
APS56_07265	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
APS56_07270	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
APS56_07295	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
APS56_07300	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
APS56_07310	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
APS56_07320	ENOG4105CHM	Aminotransferase
APS56_07325	ENOG4105CQC	Prephenate dehydratase
APS56_07335	ENOG4105C6K	Malic enzyme
APS56_07340	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
APS56_07355	ENOG4105SYT	Methylenetetrahydrofolate reductase
APS56_07360	ENOG4105C3R	Methionine synthase
APS56_07365	ENOG4105C3R	Methionine synthase
APS56_07370	ENOG4105C6T	cysteine synthase
APS56_07375	ENOG4105D7W	serine acetyltransferase
APS56_07380	ENOG4105CAY	ferredoxin--nadp reductase
APS56_07385	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
APS56_07390	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
APS56_07395	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
APS56_07405	ENOG4105C11	sulfate adenylyltransferase), subunit 2
APS56_07410	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
APS56_07420	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
APS56_07425	ENOG4105C28	cystathionine
APS56_07430	ENOG4105CFH	Aspartokinase
APS56_07450	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
APS56_07465	ENOG4105CH7	arginosuccinase
APS56_07475	ENOG4107T6X	nag kinase
APS56_07480	ENOG4107REN	Carbamoyltransferase
APS56_07485	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
APS56_07495	ENOG4105C8Y	Acetylornithine aminotransferase
APS56_07500	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
APS56_07505	ENOG4105CDH	Citrulline--aspartate ligase
APS56_07545	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
APS56_07575	ENOG4105C9U	ATP-dependent DNA helicase RecQ
APS56_07615	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
APS56_07620	ENOG4105EN6	Membrane
APS56_07645	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APS56_07665	ENOG4108ESX	Receptor
APS56_07675	ENOG4108RMU	ferritin dps family protein
APS56_07680	ENOG4105C5Q	Transcriptional regulator
APS56_07765	ENOG4105TMB	Formate nitrite transporter
APS56_07770	ENOG4105F1A	Pyruvate formate-lyase
APS56_07785	ENOG4108IQE	Amp-dependent synthetase and ligase
APS56_07790	ENOG4105RV9	Transcriptional regulator
APS56_07800	ENOG4105CHU	acetyl-coa acetyltransferase
APS56_07805	ENOG4105C1G	acyl-Coa dehydrogenase
APS56_07825	ENOG4107STW	synthase
APS56_07830	ENOG4108E2B	had-superfamily hydrolase, subfamily iib
APS56_07855	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
APS56_07875	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
APS56_07885	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
APS56_07890	ENOG4105C58	cytochrome c oxidase accessory protein ccog
APS56_07905	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
APS56_07910	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
APS56_07960	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
APS56_07990	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
APS56_08015	ENOG4106WTF	Glycosyl transferase, family 2
APS56_08020	ENOG4105CND	Glycosyl transferase, family 2
APS56_08025	ENOG4105DJT	lAO AO transport system ATPase
APS56_08030	ENOG4105D5P	Methylmalonyl-coA mutase
APS56_08035	ENOG4105CMN	Methylmalonyl-coA mutase
APS56_08040	ENOG4105CYC	Transferase
APS56_08045	ENOG4105D9Q	decarboxylase (Beta subunit)
APS56_08050	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
APS56_08060	ENOG4107QX3	carboxylase
APS56_08085	ENOG4105E0R	Deoxyhypusine synthase
APS56_08095	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
APS56_08100	ENOG4105F8V	Hydrolase, tatD family
APS56_08105	ENOG4105HDK	L-asparaginase
APS56_08145	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APS56_08150	ENOG4105C5S	asparaginyl-tRNA synthetase
APS56_08165	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
APS56_08170	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
APS56_08175	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
APS56_08180	ENOG4105CE9	30S ribosomal protein S2
APS56_08185	ENOG4108UJD	30S ribosomal protein S9
APS56_08190	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
APS56_08195	ENOG4105CNI	cell division protein FtsW
APS56_08200	ENOG4105CJN	penicillin-binding protein
APS56_08215	ENOG4105DFF	Rod shape-determining protein mreb
APS56_08235	ENOG4105DC1	bifunctional purine biosynthesis protein purh
APS56_08255	ENOG4105C59	p-type ATPase
APS56_08275	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
APS56_08285	ENOG4105CHM	Aminotransferase
APS56_08290	ENOG4105IJD	ferritin dps family protein
APS56_08315	ENOG4105BZU	Histidine kinase
APS56_08390	ENOG4105ZMH	deoxynucleoside kinase
APS56_08400	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
APS56_08405	ENOG4105DJV	ribulose-phosphate 3-epimerase
APS56_08415	ENOG4105W87	Cbs domain
APS56_08435	ENOG4105KTH	gatB Yqey
APS56_08440	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
APS56_08445	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
APS56_08455	ENOG4105DFU	Cell wall formation (By similarity)
APS56_08460	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
APS56_08465	ENOG4105CNI	cell division protein FtsW
APS56_08470	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
APS56_08475	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
APS56_08480	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
APS56_08485	ENOG4105CJN	penicillin-binding protein
APS56_08495	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
APS56_08500	ENOG4107YM1	mraZ protein
APS56_08510	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
APS56_08515	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
APS56_08520	ENOG4105CN1	protease
APS56_08525	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
APS56_08535	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APS56_08540	ENOG4107TT5	NLP P60 protein
APS56_08545	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
APS56_08550	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
APS56_08555	ENOG4105DUX	Transporter
APS56_08560	ENOG4105DUX	Transporter
APS56_08565	ENOG4105C5Z	peptidase
APS56_08570	ENOG4107EEU	hydroxymethylglutaryL-CoA reductase
APS56_08580	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
APS56_08585	ENOG4105C37	(CBS) domain
APS56_08610	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
APS56_08685	ENOG4105DZR	Type I site-specific deoxyribonuclease
APS56_08715	ENOG4107YZX	Universal stress protein
APS56_08720	ENOG4105D4P	Coproporphyrinogen iii oxidase
APS56_08725	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
APS56_08745	ENOG4105C26	Dehydrogenase
APS56_08750	ENOG4105C7B	Threonine dehydratase
APS56_08755	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
APS56_08765	ENOG4105C7K	acetolactate synthase
APS56_08770	ENOG4105C01	Dihydroxy-acid dehydratase
APS56_08775	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
APS56_08785	ENOG4105BZ1	(ABC) transporter
APS56_08795	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
APS56_08810	ENOG4105BZJ	Electron transfer flavoprotein
APS56_08815	ENOG4105C10	Electron transfer flavoprotein
APS56_08825	ENOG4105D9N	nucleoside
APS56_08830	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
APS56_08865	ENOG4105DZ0	fad dependent oxidoreductase
APS56_08870	ENOG4108UW5	maltose o-acetyltransferase
APS56_08885	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
APS56_08890	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
APS56_08895	ENOG4105CMR	udp-glucose 4-epimerase
APS56_08915	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
APS56_08935	ENOG4105C27	TonB-dependent Receptor Plug
APS56_08960	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
APS56_08970	ENOG4107QMZ	Dehydrogenase
APS56_08985	ENOG4105KVH	Transcriptional regulator
APS56_09010	ENOG4105E0X	reductase
APS56_09015	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
APS56_09025	ENOG4105CNG	UPF0061 protein
APS56_09045	ENOG4105C29	acyl-CoA thioesterase
APS56_09055	ENOG4105CBX	hi0933 family
APS56_09075	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
APS56_09090	ENOG4105FE9	pseudouridine synthase
APS56_09130	ENOG4105C7S	Dehydrogenase
APS56_09135	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
APS56_09145	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
APS56_09240	ENOG4105C9M	aspartyl-trna synthetase
APS56_09260	ENOG4108Z6B	deaminase
APS56_09265	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
APS56_09300	ENOG4105C27	TonB-dependent Receptor Plug
APS56_09315	ENOG4108UUM	single-stranded DNA-binding protein
APS56_09325	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
APS56_09335	ENOG4107RNH	Outer membrane receptor FepA
APS56_09345	ENOG4105NBK	UPF0345 protein
APS56_09360	ENOG410874W	AraC family transcriptional regulator
APS56_09375	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APS56_09390	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
APS56_09410	ENOG4105CN1	protease
APS56_09450	ENOG4108YZA	Nitrogen regulatory protein pii
APS56_09460	ENOG4108YZA	Nitrogen regulatory protein pii
APS56_09475	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
APS56_09480	ENOG4108IYU	L-aspartate oxidase
APS56_09495	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
APS56_09500	ENOG4105CD5	CoA-binding domain protein
APS56_09505	ENOG4105CFH	Aspartokinase
APS56_09515	ENOG4105KAF	membrAne
APS56_09530	ENOG4108JQ1	Dehydrogenase
APS56_09550	ENOG4105E6M	Sulphatase-modifying factor protein
APS56_09560	ENOG4105CJW	magnesium transporter
APS56_09565	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
APS56_09585	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
APS56_09595	ENOG4105DTN	riboflavin biosynthesis protein ribF
APS56_09605	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
APS56_09610	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
APS56_09615	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
APS56_09640	ENOG4105C27	TonB-dependent Receptor Plug
APS56_09675	ENOG4105ENH	Sulfatase
APS56_09685	ENOG4105ENH	Sulfatase
APS56_09710	ENOG41061MV	Arylsulfatase
APS56_09715	ENOG41061MV	Arylsulfatase
APS56_09720	ENOG41061MV	Arylsulfatase
APS56_09725	ENOG41061MV	Arylsulfatase
APS56_09735	ENOG41061MV	Arylsulfatase
APS56_09765	ENOG41061MV	Arylsulfatase
APS56_09780	ENOG41061MV	Arylsulfatase
APS56_09785	ENOG41061MV	Arylsulfatase
APS56_09810	ENOG41061MV	Arylsulfatase
APS56_09815	ENOG4105ENH	Sulfatase
APS56_09825	ENOG41061MV	Arylsulfatase
APS56_09840	ENOG4105C27	TonB-dependent Receptor Plug
APS56_09865	ENOG4105CNT	hydrolase family 2
APS56_09900	ENOG4105CBG	Sulfatase
APS56_09925	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
APS56_09935	ENOG41061MV	Arylsulfatase
APS56_09945	ENOG4105C27	TonB-dependent Receptor Plug
APS56_09975	ENOG4105C27	TonB-dependent Receptor Plug
APS56_09980	ENOG4105EP8	Glycosyl Hydrolase Family 88
APS56_10005	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
APS56_10010	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
APS56_10030	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
APS56_10040	ENOG4105VMP	Transcriptional regulator
APS56_10080	ENOG4105TT1	Ragb susd domain-containing protein
APS56_10085	ENOG4105C27	TonB-dependent Receptor Plug
APS56_10095	ENOG4105EPC	oxidoreductase
APS56_10100	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
APS56_10110	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
APS56_10120	ENOG4107ENK	receptor
APS56_10125	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
APS56_10135	ENOG4107R37	Glutamate dehydrogenase
APS56_10175	ENOG4105DZP	Membrane-associated zinc metalloprotease
APS56_10180	ENOG4108KF3	Electron transport protein SCO1 SenC
APS56_10190	ENOG4105CE1	Ferrous iron transport protein b
APS56_10205	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APS56_10210	ENOG4105DSE	periplasmic solute binding protein
APS56_10215	ENOG4105DIK	(ABC) transporter
APS56_10220	ENOG4107RPQ	ABC transporter
APS56_10225	ENOG4107RBD	ABC, transporter
APS56_10230	ENOG41080R2	UPF0102 protein
APS56_10245	ENOG4108JA2	transcriptioN-repair coupling factor
APS56_10270	ENOG4105BZM	domain protein
APS56_10275	ENOG4105UYK	outer membrane protein a
APS56_10285	ENOG41090A1	ferritin
APS56_10290	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
APS56_10295	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
APS56_10300	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
APS56_10330	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
APS56_10335	ENOG4108Y6J	UPF0403 protein
APS56_10405	ENOG4105CA0	peroxidase
APS56_10425	ENOG4105E39	Enoyl-CoA hydratase
APS56_10430	ENOG4108HWS	Histidine kinase
APS56_10445	ENOG4107SF0	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
APS56_10460	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
APS56_10465	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
APS56_10470	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
APS56_10480	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
APS56_10485	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
APS56_10490	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
APS56_10500	ENOG4105D52	delta-aminolevulinic acid dehydratase
APS56_10540	ENOG4108JQC	penicillin-binding protein 1A
APS56_10545	ENOG410647Z	gliding motility-associated lipoprotein GldH
APS56_10550	ENOG4105MA4	psp1 domain protein
APS56_10560	ENOG4105CFP	Peptidase U32
APS56_10570	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
APS56_10595	ENOG4105C31	Tryptophanyl-tRNA synthetase
APS56_10620	ENOG4105NAU	thioesterase Superfamily protein
APS56_10640	ENOG4108S0S	Nucleotidyl transferase
APS56_10645	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
APS56_10655	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
APS56_10660	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
APS56_10665	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APS56_10670	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
APS56_10680	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
APS56_10705	ENOG4105DKP	glycosyl transferase, family 9
APS56_10715	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
APS56_10730	ENOG4105C12	Phosphoribosylglycinamide synthetase
APS56_10735	ENOG4105DZS	Phenylacetate-CoA ligase
APS56_10740	ENOG4105K64	Glycosyl transferase, family 2
APS56_10760	ENOG4107ZBH	radical SAM domain protein
APS56_10765	ENOG4107RA4	Glycosyl transferase (Group 1
APS56_10775	ENOG4105I82	acetyl xylan esterase
APS56_10805	ENOG4108IJ1	Dehydrogenase
APS56_10810	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
APS56_10820	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
APS56_10830	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
APS56_10855	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
APS56_10865	ENOG4105K4H	Nlp p60 protein
APS56_10870	ENOG4105BZA	Phosphoglycerate kinase
APS56_10875	ENOG4107QRG	dna polymerase iii
APS56_10895	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
APS56_10900	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
APS56_10905	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
APS56_10915	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
APS56_10930	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
APS56_10940	ENOG4105CN1	protease
APS56_10955	ENOG4107YB6	acetyltransferase, (GNAT) family
APS56_10960	ENOG4105PGM	cation diffusion facilitator family transporter
APS56_10965	ENOG4108YZG	isomerase
APS56_10980	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
APS56_10990	ENOG4105BZU	Histidine kinase
APS56_10995	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APS56_11015	ENOG4105KRF	dihydroneopterin aldolase
APS56_11020	ENOG4105CX6	glutaminyL-tRNA synthetase
APS56_11065	ENOG4105C8F	Beta-lactamase domain protein
APS56_11075	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
APS56_11080	ENOG4108RR8	protoporphyrinogen oxidase
APS56_11090	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
APS56_11095	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
APS56_11100	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
APS56_11105	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
APS56_11120	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
APS56_11130	ENOG4105D60	lipoprotein releasing system transmembrane protein
APS56_11135	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
APS56_11145	ENOG4105CS2	ec 3.2.1.21
APS56_11165	ENOG4108R6K	riboflavin synthase, subunit alpha
APS56_11170	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
APS56_11180	ENOG4105WXV	50S ribosomal protein L32
APS56_11185	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
APS56_11190	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
APS56_11195	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
APS56_11200	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
APS56_11235	ENOG4105IIU	Aminopeptidase
APS56_11240	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
APS56_11245	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
APS56_11250	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
APS56_11255	ENOG4107T8J	thymidine kinase
APS56_11275	ENOG4108RG0	uracil-dna glycosylase
APS56_11285	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
APS56_11300	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
APS56_11310	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
APS56_11330	ENOG4105CNT	hydrolase family 2
APS56_11345	ENOG4105C27	TonB-dependent Receptor Plug
APS56_11355	ENOG4105BZU	Histidine kinase
APS56_11370	ENOG4105CDV	Ompa motb domain protein
APS56_11375	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
APS56_11385	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
APS56_11390	ENOG4105DWF	phosphomethylpyrimidine kinase
APS56_11405	ENOG4108B1Q	Ribonuclease
APS56_11410	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
APS56_11415	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
APS56_11420	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
APS56_11425	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
APS56_11435	ENOG4105CA9	Pyruvate kinase
APS56_11455	ENOG4105P0I	Adenylate cyclase
APS56_11470	ENOG4108JQB	penicillin-binding protein 1C
APS56_11475	ENOG4105DN3	alpha-2-macroglobulin domain protein
APS56_11480	ENOG4107QUV	Domain protein
APS56_11505	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APS56_11525	ENOG4107QVM	von Willebrand factor, type A
APS56_11545	ENOG41077A9	carbonic anhydrase
APS56_11560	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APS56_11605	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
APS56_11615	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
APS56_11625	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
APS56_11655	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
APS56_11660	ENOG4108JQC	penicillin-binding protein 1A
APS56_11685	ENOG4105Y3E	Modulates RecA activity (By similarity)
APS56_11700	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APS56_11710	ENOG4105CPC	Aldo Keto reductase
APS56_11715	ENOG4105ER2	Ompa motb domain protein
APS56_11720	ENOG4105CGK	Exodeoxyribonuclease III
APS56_11730	ENOG4105IIU	Aminopeptidase
APS56_11735	ENOG4105E33	succinate dehydrogenase
APS56_11755	ENOG4107T6F	Xaa-Pro aminopeptidase
APS56_11760	ENOG4105CFH	Aspartokinase
APS56_11800	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
APS56_11810	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
APS56_11835	ENOG4105C9B	Cysteine desulfurase
APS56_11840	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
APS56_11845	ENOG4105VG1	fes assembly suf system protein
APS56_11870	ENOG4105C03	ribonuclease
APS56_11875	ENOG4105K70	DNA-binding protein
APS56_11880	ENOG4105CEN	a g-specific adenine glycosylase
APS56_11885	ENOG4108UUM	single-stranded DNA-binding protein
APS56_11890	ENOG4105C37	(CBS) domain
APS56_11910	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
APS56_11915	ENOG4105K46	50S ribosomal protein l27
APS56_11940	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
APS56_11950	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
APS56_11960	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
APS56_11975	ENOG4107SQI	penicillin amidase
APS56_12015	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
APS56_12020	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
APS56_12025	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
APS56_12035	ENOG4105C27	TonB-dependent Receptor Plug
APS56_12040	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
APS56_12050	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
APS56_12055	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
APS56_12060	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
APS56_12075	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
APS56_12090	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
APS56_12100	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
APS56_12110	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
APS56_12120	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
APS56_12125	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
APS56_12130	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
APS56_12135	ENOG4105D78	K07001 NTE family protein
APS56_12145	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
APS56_12155	ENOG4107QP8	phosphohexose isomerase
APS56_12160	ENOG4108KPZ	tonB-dependent Receptor
APS56_12175	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
APS56_12190	ENOG4105BZU	Histidine kinase
APS56_12200	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
APS56_12210	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APS56_12225	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
APS56_12230	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
APS56_12235	ENOG4105BZW	Glycerate kinase
APS56_12245	ENOG4107RJ9	Cell division protein FtsX
APS56_12250	ENOG4108PCN	EamA-like transporter family
APS56_12255	ENOG4105C8T	Leucyl-tRNA synthetase
APS56_12260	ENOG4105W3H	MtN3 and saliva related transmembrane protein
APS56_12265	ENOG4105DCF	alanine dehydrogenase
APS56_12275	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
APS56_12305	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
APS56_12310	ENOG4108VVK	transcriptional Regulator, AsnC
APS56_12315	ENOG4105M08	Membrane
APS56_12330	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
APS56_12335	ENOG4105CD3	dihydroorotase
APS56_12350	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
APS56_12365	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
APS56_12375	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
APS56_12390	ENOG4105C93	Xylose Isomerase
APS56_12395	ENOG4107QNK	)-transporter
APS56_12405	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APS56_12410	ENOG4105BZU	Histidine kinase
APS56_12420	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
APS56_12435	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
APS56_12455	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
APS56_12460	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
APS56_12465	ENOG4105DGN	Electron transport complex
APS56_12470	ENOG4105DZB	Electron transport complex
APS56_12475	ENOG4108UQQ	Electron transport complex
APS56_12480	ENOG4105D6A	Electron transport complex
APS56_12485	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
APS56_12490	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
APS56_12500	ENOG4108ZIT	Ferredoxin, 2FE-2S
APS56_12530	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
APS56_12540	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
APS56_12545	ENOG4105K5M	30s ribosomal protein S16
APS56_12550	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
APS56_12555	ENOG4105C0B	DNA polymerase III (alpha subunit)
APS56_12570	ENOG4108NEV	two component transcriptional regulator, LytTR family
APS56_12575	ENOG4108HRK	Histidine kinase
APS56_12585	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APS56_12590	ENOG4105C19	ABC transporter
APS56_12595	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
APS56_12600	ENOG4105DFG	type I secretion outer membrane protein
APS56_12610	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
APS56_12625	ENOG4105D2H	Uronic isomerase
APS56_12630	ENOG4107QZW	Altronate oxidoreductase
APS56_12635	ENOG4105CTX	dehydratase
APS56_12640	ENOG4105ETE	Transcriptional regulator (LacI family
APS56_12650	ENOG4107TDE	lipolytic protein G-D-S-L family
APS56_12655	ENOG4105F5H	Glycosyl Hydrolase Family 88
APS56_12715	ENOG4105C27	TonB-dependent Receptor Plug
APS56_12720	ENOG4107TDE	lipolytic protein G-D-S-L family
APS56_12750	ENOG4105ENE	Histidine kinase
APS56_12755	ENOG4105WH1	Two component transcriptional regulator luxr family
APS56_12760	ENOG4105SXS	Protein of unknown function (DUF456)
APS56_12770	ENOG4105CKK	Glycosyl transferase, family 2
APS56_12785	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
APS56_12790	ENOG4105CSA	Coproporphyrinogen iii oxidase
APS56_12795	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
APS56_12805	ENOG4105MSB	protein, conserved in bacteria
APS56_12815	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
APS56_12830	ENOG4108UZ3	Transporter
APS56_12850	ENOG4105UGU	tonB-dependent Receptor
APS56_12870	ENOG4105G6Z	alkaline phosphatase
APS56_12875	ENOG4107YZX	Universal stress protein
APS56_12880	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
APS56_12885	ENOG4105CHV	Transcription elongation factor NusA
APS56_12890	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
APS56_12905	ENOG4107SFQ	iron-sulfur binding
APS56_12930	ENOG4105E2S	oxidase) subunit II
APS56_12935	ENOG4105BZ9	Cytochrome C oxidase, subunit I
APS56_12955	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
APS56_12960	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
APS56_12975	ENOG4105C6K	Malic enzyme
APS56_12980	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
APS56_12990	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
APS56_13015	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
APS56_13020	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
APS56_13025	ENOG4105CCU	oxidase (Subunit III)
APS56_13040	ENOG4108KF3	Electron transport protein SCO1 SenC
APS56_13045	ENOG4108SJC	Membrane
APS56_13055	ENOG4105C19	ABC transporter
APS56_13060	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APS56_13065	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APS56_13070	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
APS56_13075	ENOG4105DFG	type I secretion outer membrane protein
APS56_13080	ENOG41072GX	Peptidase M22 Glycoprotease
APS56_13085	ENOG4105D64	Mechanosensitive ion channel
APS56_13090	ENOG4105KA3	membrAne
APS56_13095	ENOG41083MR	nifu domain-containing protein
APS56_13105	ENOG4108Z0R	Transferase
APS56_13110	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
APS56_13125	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APS56_13130	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
APS56_13140	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
APS56_13150	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
APS56_13155	ENOG4105EV9	Alpha Beta Hydrolase
APS56_13165	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
APS56_13175	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
APS56_13190	ENOG41083X6	30S ribosomal protein S21
APS56_13195	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APS56_13235	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
APS56_13260	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
APS56_13275	ENOG4105K63	Thioredoxin
APS56_13295	ENOG4105WH1	Two component transcriptional regulator luxr family
APS56_13310	ENOG4105C2M	dna polymerase I
APS56_13320	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
APS56_13325	ENOG4105CCT	upf0313 protein
APS56_13330	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
APS56_13360	ENOG4105KVH	Transcriptional regulator
APS56_13405	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
APS56_13410	ENOG4108WQH	regulatoR
APS56_13415	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
APS56_13440	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
APS56_13450	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
APS56_13470	ENOG4108V0P	LemA family
APS56_13485	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
APS56_13530	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
APS56_13535	ENOG4105C27	TonB-dependent Receptor Plug
APS56_13590	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
APS56_13610	ENOG4105K6H	D-cysteine desulfhydrase
APS56_13620	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
APS56_13640	ENOG4105CRK	lysyL-tRNA synthetase
APS56_13645	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
APS56_13665	ENOG4105CSR	polyphosphate kinase 2
APS56_13670	ENOG4105ETE	Transcriptional regulator (LacI family
APS56_13690	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
APS56_13700	ENOG41061MV	Arylsulfatase
APS56_13705	ENOG4108PTS	heparinase ii
APS56_13715	ENOG4106AM8	polysaccharide lyase family 8
APS56_13720	ENOG4105C27	TonB-dependent Receptor Plug
APS56_13730	ENOG4105C27	TonB-dependent Receptor Plug
APS56_13745	ENOG4106AM8	polysaccharide lyase family 8
APS56_13750	ENOG4105EP8	Glycosyl Hydrolase Family 88
APS56_13755	ENOG4105CNT	hydrolase family 2
APS56_13760	ENOG4105CNT	hydrolase family 2
APS56_13765	ENOG4105EPC	oxidoreductase
APS56_13770	ENOG4105C1G	acyl-Coa dehydrogenase
APS56_13775	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
APS56_13785	ENOG4109015	Biopolymer transport protein exbD tolR
APS56_13795	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
APS56_13805	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
APS56_13840	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APS56_13855	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APS56_13860	ENOG4105W5Q	DNA repair protein (RadC
APS56_13870	ENOG4105U0R	haloacid dehalogenase-like hydrolase
APS56_13890	ENOG4105D1H	recombination factor protein RarA
APS56_13900	ENOG4105C2N	RNA methyltransferase TrmH family group 3
APS56_13915	ENOG4105C27	TonB-dependent Receptor Plug
APS56_13925	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
APS56_13930	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
APS56_13935	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
APS56_13940	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
APS56_13945	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
APS56_13950	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
APS56_13955	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
APS56_13960	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APS56_13965	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
APS56_13970	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
APS56_13975	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
APS56_13980	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
APS56_13985	ENOG4105WNB	50s ribosomal protein l29
APS56_13990	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
APS56_13995	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
APS56_14000	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
APS56_14005	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APS56_14010	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
APS56_14015	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
APS56_14020	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
APS56_14025	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
APS56_14030	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
APS56_14035	ENOG41084HK	50S ribosomal protein L30
APS56_14040	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
APS56_14045	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
APS56_14050	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
APS56_14055	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APS56_14060	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
APS56_14065	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
APS56_14070	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APS56_14075	ENOG4108ZT0	50S ribosomal protein l17
APS56_14080	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
APS56_14085	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
APS56_14105	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
APS56_14110	ENOG4105KNE	Phosphatidate cytidylyltransferase
APS56_14120	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
APS56_14125	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
APS56_14130	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
APS56_14140	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
APS56_14145	ENOG41062IR	nudix hydrolase
APS56_14170	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
APS56_14175	ENOG4105FE9	pseudouridine synthase
APS56_14185	ENOG4108JYZ	YitT family
APS56_14195	ENOG4105D7A	ATP-binding protein
APS56_14200	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
APS56_14230	ENOG4105C9M	aspartyl-trna synthetase
APS56_14235	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
APS56_14250	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APS56_14255	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
APS56_14265	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
APS56_14270	ENOG4105CHR	reductase
APS56_14275	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
APS56_14280	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
APS56_14290	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APS56_14300	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
APS56_14305	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
APS56_14315	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
APS56_14320	ENOG4105D2N	Aldolase
APS56_14330	ENOG4108RWN	rrna methyltransferase
APS56_14340	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
APS56_14345	ENOG4105C1A	potassium transporter peripheral membrane
APS56_14350	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
APS56_14355	ENOG4105E6M	Sulphatase-modifying factor protein
APS56_14380	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
APS56_14385	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
APS56_14395	ENOG4105SFS	phosphoesterase RecJ domain protein
APS56_14400	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
APS56_14405	ENOG4105VEQ	Cold shock protein
APS56_14410	ENOG4105VEQ	Cold shock protein
APS56_14425	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
APS56_14435	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
APS56_14450	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
APS56_14480	ENOG4105C3F	Signal peptidase i
APS56_14485	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
APS56_14495	ENOG4105FA0	parb-like partition protein
APS56_14500	ENOG4107QJE	Chromosome Partitioning Protein
APS56_14530	ENOG4105CMN	Methylmalonyl-coA mutase
APS56_14540	ENOG4105DBI	uridine monophosphokinase
APS56_14545	ENOG4107TJ9	Cytochrome
APS56_14550	ENOG4105D8V	Glucose sorbosone dehydrogenase
APS56_14570	ENOG410624X	efflux transporter, rnd family, mfp subunit
APS56_14590	ENOG4105R8C	Transcriptional regulator
APS56_14605	ENOG4105C27	TonB-dependent Receptor Plug
APS56_14615	ENOG4105EPC	oxidoreductase
APS56_14655	ENOG4108R96	Methyltransferase, YaeB family
APS56_14695	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
APS56_14705	ENOG4105EGD	dinuclear metal center protein, YbgI family
APS56_14710	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
APS56_14725	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
APS56_14730	ENOG4105K3M	)-transporter
APS56_14750	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
APS56_14760	ENOG4105K6V	RNA polymerase
APS56_14765	ENOG4107R0I	Cell wall formation (By similarity)
APS56_14770	ENOG4105CHM	Aminotransferase
APS56_14780	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
APS56_14815	ENOG4105BZU	Histidine kinase
APS56_14820	ENOG4105C75	arginyL-tRNA synthetase
APS56_14830	ENOG4105CHH	sulfate transporter
APS56_14835	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
APS56_14840	ENOG4105CPF	Cell wall formation (By similarity)
APS56_14850	ENOG4105C34	Pseudouridine synthase
APS56_14860	ENOG4105CGD	Nad-dependent epimerase dehydratase
APS56_14865	ENOG4105D1Q	UPF0246 protein
APS56_14885	ENOG4105CNM	Receptor
APS56_14890	ENOG4105C1J	atp-dependent rna helicase
APS56_14900	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
APS56_14915	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
APS56_14920	ENOG4105KAF	membrAne
APS56_14925	ENOG4105CEP	NADH dehydrogenase
APS56_14930	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
APS56_14935	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
APS56_14940	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
APS56_14945	ENOG4105DK0	Indole-3-glycerol phosphate synthase
APS56_14950	ENOG4108I0Q	anthranilate phosphoribosyltransferase
APS56_14955	ENOG4105DDQ	anthranilate synthase
APS56_14960	ENOG4105CRQ	synthase (Component I)
APS56_14970	ENOG41085GJ	domain protein
APS56_14985	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
APS56_14990	ENOG4105DMW	Dehydrogenase reductase
APS56_15005	ENOG4105C3M	thioredoxin reductase
APS56_15040	ENOG4105CBG	Sulfatase
APS56_15045	ENOG4105C26	Dehydrogenase
APS56_15050	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
APS56_15055	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
APS56_15060	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
APS56_15065	ENOG4105CMG	Carbohydrate kinase
APS56_15085	ENOG4105EY3	heparinase II III family protein
APS56_15105	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
APS56_15115	ENOG4105CXK	mandelate racemase muconate lactonizing
APS56_15120	ENOG4105C27	TonB-dependent Receptor Plug
APS56_15150	ENOG4105C27	TonB-dependent Receptor Plug
APS56_15165	ENOG4107YCY	Transcriptional regulator
APS56_15170	ENOG4105DJB	Major Facilitator Superfamily
APS56_15190	ENOG4105EMN	RNA polymerase sigma factor
APS56_15195	ENOG4105BZ1	(ABC) transporter
APS56_15215	ENOG41081WG	50s ribosomal protein l31
APS56_15235	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
APS56_15265	ENOG4105VG0	50S ribosomal protein l34
APS56_15270	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
APS56_15295	ENOG4105CGY	Dna recombination protein
APS56_15300	ENOG4105E0A	ABC, transporter
APS56_15305	ENOG4105EHG	Permease protein
APS56_15340	ENOG4105EMN	RNA polymerase sigma factor
APS56_15355	ENOG4107QTF	adenylosuccinate lyase
APS56_15375	ENOG4105DVC	DnaJ domain protein
APS56_15380	ENOG4105C5H	ABC transporter
APS56_15400	ENOG4105C26	Dehydrogenase
APS56_15405	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
APS56_15410	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
APS56_15430	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
APS56_15435	ENOG4108RWN	rrna methyltransferase
APS56_15455	ENOG4105CD3	dihydroorotase
APS56_15465	ENOG4105CIN	aminoacyl-histidine dipeptidase
APS56_15475	ENOG4105DHU	Bile acid
APS56_15480	ENOG4105C8N	cysteinyl-tRNA synthetase
APS56_15485	ENOG4105EUJ	GTP cyclohydrolase i
APS56_15500	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
APS56_15510	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
APS56_15530	ENOG41061MV	Arylsulfatase
APS56_15540	ENOG4105CNT	hydrolase family 2
APS56_15545	ENOG4105CNT	hydrolase family 2
APS56_15550	ENOG4105C27	TonB-dependent Receptor Plug
APS56_15560	ENOG4105C27	TonB-dependent Receptor Plug
APS56_15575	ENOG4105CBG	Sulfatase
APS56_15595	ENOG4105C27	TonB-dependent Receptor Plug
APS56_15630	ENOG4105BZU	Histidine kinase
APS56_15640	ENOG4105DY9	regulatoR
APS56_15705	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
APS56_15750	ENOG4105CJ1	ABC, transporter
APS56_15760	ENOG4107RAN	Peptidase, M16
APS56_15775	ENOG4105C27	TonB-dependent Receptor Plug
APS56_15820	ENOG4108UJU	UPF0301 protein
APS56_15825	ENOG4105K70	DNA-binding protein
APS56_15830	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
APS56_15835	ENOG4105C9U	ATP-dependent DNA helicase RecQ
APS56_15855	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
APS56_15890	ENOG4105EE0	oxidoreductase
APS56_15915	ENOG4107QUY	Guanine deaminase
APS56_15925	ENOG4105DY9	regulatoR
APS56_15930	ENOG4108HRK	Histidine kinase
APS56_16065	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
APS56_16080	ENOG4105D7N	magnesium and cobalt transport protein CorA
APS56_16095	ENOG4108Z03	MAF-like protein
APS56_16120	ENOG4105CRE	cytochrome C
APS56_16125	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
APS56_16135	ENOG4105C9Q	fumarate hydratase class II
APS56_16140	ENOG4105D3R	alkyl hydroperoxide reductase
APS56_16150	ENOG4107RNH	Outer membrane receptor FepA
APS56_16155	ENOG4105K89	arsenate reductase
APS56_16165	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
APS56_16175	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
APS56_16190	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
APS56_16225	ENOG4105CFG	Acts as a chaperone (By similarity)
APS56_16250	ENOG4105EA8	2-Nitropropane dioxygenase
APS56_16265	ENOG4105C0H	protease
APS56_16270	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
APS56_16280	ENOG4105HHA	aminodeoxychorismate lyase
APS56_16305	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
APS56_16315	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
APS56_16325	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
APS56_16335	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
APS56_16340	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
APS56_16355	ENOG4105CGH	5'-nucleotidase
APS56_16370	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
APS56_16395	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
APS56_16400	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
APS56_16405	ENOG4105CKK	Glycosyl transferase, family 2
APS56_16415	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
APS56_16435	ENOG4105KVH	Transcriptional regulator
APS56_16485	ENOG4105CD3	dihydroorotase
APS56_16515	ENOG4107RJ1	sodium solute
APS56_16520	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
APS56_16535	ENOG4107RZZ	dna polymerase iii epsilon subunit
APS56_16540	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
APS56_16550	ENOG4105CEV	competence damage-inducible protein
APS56_16555	ENOG4105KDC	50s ribosomal protein l28
APS56_16560	ENOG41083ND	50S ribosomal protein L33
APS56_16565	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APS56_16575	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
APS56_16590	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
APS56_16600	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
APS56_16605	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APS56_16610	ENOG4107QIJ	Aconitate hydratase 2
APS56_16615	ENOG4108I0Z	Aconitate hydratase
APS56_16625	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
APS56_16630	ENOG4105VJV	50s ribosomal protein L35
APS56_16635	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
APS56_16640	ENOG4105C22	threonyL-tRNA synthetase