locus-tag	class	description
DBV39_00050	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DBV39_00105	COG0740	serine-type endopeptidase activity
DBV39_00320	COG1368	sulfuric ester hydrolase activity
DBV39_00335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DBV39_00340	COG2271	Major facilitator Superfamily
DBV39_00345	COG0668	transmembrane transport
DBV39_00355	COG1063	alcohol dehydrogenase
DBV39_00360	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DBV39_00370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DBV39_00375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DBV39_00400	COG1538	Outer membrane efflux protein
DBV39_00405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBV39_00410	COG4591	ABC-type transport system involved in lipoprotein release permease component
DBV39_00410	COG1136	(ABC) transporter
DBV39_00415	COG0577	efflux transmembrane transporter activity
DBV39_00415	COG1136	(ABC) transporter
DBV39_00450	COG0410	ABC transporter
DBV39_00465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBV39_00470	COG0842	Transport permease protein
DBV39_00470	COG1129	ABC transporter
DBV39_00475	COG0842	Transport permease protein
DBV39_00480	COG1960	acyl-CoA dehydrogenase activity
DBV39_00485	COG0384	phenazine biosynthesis protein PhzF
DBV39_00490	COG3181	Tripartite tricarboxylate transporter family receptor
DBV39_00495	COG2135	peptidase activity
DBV39_00515	COG0306	phosphate transporter
DBV39_00525	COG2267	carboxylic ester hydrolase activity
DBV39_00530	COG2995	paraquat-inducible protein a
DBV39_00535	COG3008	intermembrane lipid transfer
DBV39_00535	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DBV39_00555	COG1487	ribonuclease activity
DBV39_00575	COG1960	acyl-CoA dehydrogenase activity
DBV39_00580	COG1960	acyl-CoA dehydrogenase activity
DBV39_00595	COG1024	Enoyl-CoA hydratase
DBV39_00655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DBV39_00670	COG1999	signal sequence binding
DBV39_00685	COG3845	ABC transporter
DBV39_00690	COG4603	Belongs to the binding-protein-dependent transport system permease family
DBV39_00695	COG1079	Belongs to the binding-protein-dependent transport system permease family
DBV39_00715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_00720	COG3706	GGDEF domain
DBV39_00725	COG4771	TonB-dependent receptor
DBV39_00760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DBV39_00815	COG0114	fumarate hydratase activity
DBV39_00830	COG1132	(ABC) transporter
DBV39_00950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_00955	COG1024	Enoyl-CoA hydratase
DBV39_00970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBV39_01020	COG3485	protocatechuate 3,4-dioxygenase
DBV39_01030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DBV39_01035	COG0596	Alpha beta hydrolase
DBV39_01040	COG4829	muconolactone delta-isomerase
DBV39_01055	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DBV39_01125	COG1368	sulfuric ester hydrolase activity
DBV39_01130	COG2161	toxin-antitoxin pair type II binding
DBV39_01160	COG0156	8-amino-7-oxononanoate synthase activity
DBV39_01165	COG0604	alcohol dehydrogenase
DBV39_01165	COG3321	synthase
DBV39_01200	COG1596	polysaccharide export
DBV39_01225	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DBV39_01230	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DBV39_01300	COG0463	Glycosyl transferase, family 2
DBV39_01305	COG0438	transferase activity, transferring glycosyl groups
DBV39_01305	COG1216	Glycosyl transferase, family 2
DBV39_01375	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DBV39_01380	COG1187	pseudouridine synthase activity
DBV39_01385	COG0779	Required for maturation of 30S ribosomal subunits
DBV39_01390	COG0195	Participates in both transcription termination and antitermination
DBV39_01390	COG2251	uridine kinase activity
DBV39_01395	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DBV39_01400	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DBV39_01405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DBV39_01410	COG1217	gtp-binding protein TYPA
DBV39_01435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DBV39_01435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DBV39_01440	COG0501	Belongs to the peptidase M48B family
DBV39_01455	COG1722	exodeoxyribonuclease VII activity
DBV39_01460	COG0142	geranyltranstransferase activity
DBV39_01470	COG0360	Binds together with S18 to 16S ribosomal RNA
DBV39_01475	COG2965	DNA replication, synthesis of RNA primer
DBV39_01480	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DBV39_01485	COG0359	binds to the 23S rRNA
DBV39_01490	COG0305	Participates in initiation and elongation during chromosome replication
DBV39_01495	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DBV39_01505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DBV39_01530	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DBV39_01535	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DBV39_01565	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DBV39_01575	COG3642	lipopolysaccharide core region biosynthetic process
DBV39_01585	COG3842	ATPase activity
DBV39_01590	COG1176	ABC-type spermidine putrescine transport system, permease component I
DBV39_01595	COG1177	transmembrane transport
DBV39_01600	COG1393	Belongs to the ArsC family
DBV39_01610	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DBV39_01615	COG0704	Plays a role in the regulation of phosphate uptake
DBV39_01620	COG1335	isochorismatase
DBV39_01625	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DBV39_01630	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DBV39_01630	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DBV39_01635	COG1643	Atp-dependent helicase
DBV39_01650	COG0859	PFAM glycosyl transferase family 9
DBV39_01670	COG1132	(ABC) transporter
DBV39_01720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DBV39_01735	COG0045	succinate-CoA ligase (ADP-forming) activity
DBV39_01735	COG1042	CoA-binding domain protein
DBV39_01735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DBV39_01770	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DBV39_01780	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DBV39_01795	COG0424	maF-like protein
DBV39_01800	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DBV39_01805	COG0799	negative regulation of ribosome biogenesis
DBV39_01810	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DBV39_01820	COG0151	Belongs to the GarS family
DBV39_01825	COG0217	transcriptional regulatory protein
DBV39_01840	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DBV39_01845	COG0308	aminopeptidase N
DBV39_01875	COG0312	modulator of DNA gyrase
DBV39_01880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DBV39_01885	COG0277	FAD linked oxidase domain protein
DBV39_01890	COG0277	FAD linked oxidase domain protein
DBV39_01895	COG0277	FAD linked oxidase domain protein
DBV39_01900	COG0247	lactate metabolic process
DBV39_01920	COG0482	sulfurtransferase activity
DBV39_01925	COG0625	glutathione transferase activity
DBV39_01935	COG3909	cytochrome
DBV39_01970	COG4115	mRNA cleavage
DBV39_01975	COG2161	toxin-antitoxin pair type II binding
DBV39_02115	COG1024	Enoyl-CoA hydratase
DBV39_02130	COG2079	MmgE PrpD family protein
DBV39_02175	COG1024	Enoyl-CoA hydratase
DBV39_02220	COG3436	PFAM IS66 Orf2 family protein
DBV39_02240	COG1024	Enoyl-CoA hydratase
DBV39_02250	COG1960	acyl-CoA dehydrogenase activity
DBV39_02255	COG1960	acyl-CoA dehydrogenase activity
DBV39_02265	COG0531	amino acid
DBV39_02305	COG2860	membrane
DBV39_02330	COG1132	(ABC) transporter
DBV39_02360	COG0431	NADPH-dependent FMN reductase
DBV39_02365	COG0346	lactoylglutathione lyase activity
DBV39_02375	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DBV39_02380	COG4208	sulfate ABC transporter
DBV39_02390	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DBV39_02420	COG2005	Transcriptional regulator
DBV39_02420	COG3585	molybdate ion transport
DBV39_02440	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DBV39_02475	COG3012	SEC-C Motif Domain Protein
DBV39_02475	COG3318	Belongs to the UPF0149 family
DBV39_02490	COG3300	MHYT domain
DBV39_02490	COG5001	Diguanylate cyclase
DBV39_02500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBV39_02505	COG0492	ferredoxin-NADP+ reductase activity
DBV39_02510	COG1309	transcriptional regulator
DBV39_02525	COG0019	diaminopimelate decarboxylase activity
DBV39_02535	COG4181	ATPase activity
DBV39_02580	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DBV39_02595	COG0179	Fumarylacetoacetate (FAA) hydrolase
DBV39_02605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DBV39_02610	COG0583	DNA-binding transcription factor activity
DBV39_02615	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_02635	COG0179	Fumarylacetoacetate (FAA) hydrolase
DBV39_02645	COG3181	Tripartite tricarboxylate transporter family receptor
DBV39_02650	COG0583	DNA-binding transcription factor activity
DBV39_02655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_02670	COG0183	Belongs to the thiolase family
DBV39_02695	COG3181	Tripartite tricarboxylate transporter family receptor
DBV39_02700	COG0604	alcohol dehydrogenase
DBV39_02710	COG0789	Transcriptional regulator
DBV39_02715	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DBV39_02725	COG0861	Integral membrane protein TerC family
DBV39_02735	COG4251	negative regulation of phosphorylation
DBV39_02745	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DBV39_02750	COG3181	Tripartite tricarboxylate transporter family receptor
DBV39_02780	COG5001	Diguanylate cyclase
DBV39_02780	COG4251	negative regulation of phosphorylation
DBV39_02780	COG2203	Gaf domain
DBV39_02780	COG3706	GGDEF domain
DBV39_02795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DBV39_02810	COG1960	acyl-CoA dehydrogenase activity
DBV39_02815	COG1960	acyl-CoA dehydrogenase activity
DBV39_02820	COG2832	Protein of unknown function (DUF454)
DBV39_02840	COG1024	Enoyl-CoA hydratase
DBV39_02855	COG0583	DNA-binding transcription factor activity
DBV39_02860	COG1024	Enoyl-CoA hydratase
DBV39_02865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DBV39_02905	COG1250	3-hydroxyacyl-CoA dehydrogenase
DBV39_02905	COG1024	Enoyl-CoA hydratase
DBV39_02910	COG0511	ligase activity, forming carbon-carbon bonds
DBV39_02915	COG3181	Tripartite tricarboxylate transporter family receptor
DBV39_02925	COG0439	Biotin carboxylase
DBV39_02930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_02945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DBV39_02955	COG3971	2-oxopent-4-enoate hydratase activity
DBV39_02970	COG2391	methyltransferase activity
DBV39_02990	COG0517	IMP dehydrogenase activity
DBV39_02990	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DBV39_02995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DBV39_03000	COG0596	Alpha beta hydrolase
DBV39_03005	COG1012	belongs to the aldehyde dehydrogenase family
DBV39_03015	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DBV39_03025	COG0824	Thioesterase
DBV39_03035	COG0438	transferase activity, transferring glycosyl groups
DBV39_03040	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DBV39_03045	COG0469	pyruvate kinase activity
DBV39_03050	COG3118	belongs to the thioredoxin family
DBV39_03055	COG0628	permease
DBV39_03080	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DBV39_03090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DBV39_03110	COG4221	oxidoreductase activity
DBV39_03130	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DBV39_03135	COG2137	regulation of response to DNA damage stimulus
DBV39_03145	COG0045	succinate-CoA ligase (ADP-forming) activity
DBV39_03150	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DBV39_03160	COG0181	hydroxymethylbilane synthase activity
DBV39_03210	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DBV39_03225	COG1289	transmembrane transporter activity
DBV39_03245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DBV39_03255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_03260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DBV39_03270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBV39_03280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBV39_03295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DBV39_03315	COG1278	Cold shock
DBV39_03325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DBV39_03355	COG0339	signal peptide processing
DBV39_03385	COG0411	ABC transporter
DBV39_03400	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_03405	COG1024	Enoyl-CoA hydratase
DBV39_03420	COG2084	Dehydrogenase
DBV39_03425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_03430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DBV39_03435	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DBV39_03455	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBV39_03460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DBV39_03480	COG0675	Transposase, IS605 OrfB family
DBV39_03510	COG0318	PFAM AMP-dependent synthetase and ligase
DBV39_03515	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DBV39_03520	COG0047	phosphoribosylformylglycinamidine synthase activity
DBV39_03520	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DBV39_03530	COG0519	Catalyzes the synthesis of GMP from XMP
DBV39_03530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DBV39_03575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DBV39_03590	COG0789	Transcriptional regulator
DBV39_03605	COG2608	mercury ion transmembrane transporter activity
DBV39_03650	COG4691	Plasmid stability protein
DBV39_03655	COG1487	ribonuclease activity
DBV39_03710	COG1902	pentaerythritol trinitrate reductase activity
DBV39_03720	COG1538	Outer membrane efflux protein
DBV39_03770	COG2146	nitrite reductase [NAD(P)H] activity
DBV39_03800	COG4974	Belongs to the 'phage' integrase family
DBV39_03810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBV39_03820	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DBV39_03845	COG1137	ATPase activity
DBV39_03865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DBV39_03930	COG2188	Transcriptional regulator
DBV39_03935	COG0028	Belongs to the TPP enzyme family
DBV39_03945	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_03970	COG1216	Glycosyl transferase, family 2
DBV39_03985	COG1132	(ABC) transporter
DBV39_04010	COG3475	LICD family
DBV39_04020	COG3436	PFAM IS66 Orf2 family protein
DBV39_04035	COG0297	glycogen (starch) synthase activity
DBV39_04055	COG1086	Polysaccharide biosynthesis protein
DBV39_04065	COG0297	glycogen (starch) synthase activity
DBV39_04080	COG0463	Glycosyl transferase, family 2
DBV39_04090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBV39_04110	COG2244	polysaccharide biosynthetic process
DBV39_04125	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DBV39_04145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DBV39_04150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DBV39_04150	COG0543	2 iron, 2 sulfur cluster binding
DBV39_04205	COG2433	Pfam Transposase IS66
DBV39_04230	COG2192	nodulation
DBV39_04245	COG1696	Membrane protein involved in D-alanine export
DBV39_04250	COG3547	Transposase (IS116 IS110 IS902 family)
DBV39_04270	COG1216	Glycosyl transferase, family 2
DBV39_04275	COG0463	Glycosyl transferase, family 2
DBV39_04375	COG4106	trans-aconitate 2-methyltransferase activity
DBV39_04395	COG2826	transposase and inactivated derivatives, IS30 family
DBV39_04410	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DBV39_04430	COG4974	Belongs to the 'phage' integrase family
DBV39_04470	COG1446	asparaginase
DBV39_04480	COG1295	ribonuclease BN
DBV39_04490	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DBV39_04510	COG0066	3-isopropylmalate dehydratase activity
DBV39_04520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DBV39_04540	COG0135	phosphoribosylanthranilate isomerase activity
DBV39_04570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DBV39_04595	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DBV39_04600	COG2814	Major facilitator Superfamily
DBV39_04605	COG0583	DNA-binding transcription factor activity
DBV39_04610	COG3181	Tripartite tricarboxylate transporter family receptor
DBV39_04620	COG1320	monovalent cation:proton antiporter activity
DBV39_04625	COG2212	antiporter activity
DBV39_04630	COG1863	multisubunit Na H antiporter MnhE subunit
DBV39_04635	COG0651	ATP synthesis coupled electron transport
DBV39_04640	COG1006	Multisubunit Na H antiporter MnhC subunit
DBV39_04645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DBV39_04645	COG2111	Na H antiporter
DBV39_04650	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DBV39_04655	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_04670	COG0583	DNA-binding transcription factor activity
DBV39_04680	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_04685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DBV39_04700	COG2841	Protein conserved in bacteria
DBV39_04720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DBV39_04725	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DBV39_04740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBV39_04755	COG0531	amino acid
DBV39_04760	COG1982	Orn Lys Arg decarboxylase major
DBV39_04780	COG0076	glutamate decarboxylase activity
DBV39_04785	COG0531	amino acid
DBV39_04790	COG0004	ammonium transporteR
DBV39_04795	COG0347	Belongs to the P(II) protein family
DBV39_04805	COG2960	long-chain fatty acid transporting porin activity
DBV39_04810	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DBV39_04815	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DBV39_04820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DBV39_04830	COG0776	regulation of translation
DBV39_04895	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBV39_04900	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DBV39_04905	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DBV39_04950	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_04960	COG0596	Alpha beta hydrolase
DBV39_05005	COG1063	alcohol dehydrogenase
DBV39_05035	COG0589	response to stress
DBV39_05045	COG2814	Major facilitator Superfamily
DBV39_05060	COG2814	Major facilitator Superfamily
DBV39_05075	COG2183	response to ionizing radiation
DBV39_05080	COG1024	Enoyl-CoA hydratase
DBV39_05095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_05105	COG3181	Tripartite tricarboxylate transporter family receptor
DBV39_05110	COG2079	MmgE PrpD family protein
DBV39_05185	COG2363	Small membrane protein
DBV39_05205	COG0587	DNA-directed DNA polymerase activity
DBV39_05225	COG1793	dna ligase
DBV39_05225	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DBV39_05230	COG1793	dna ligase
DBV39_05235	COG1201	RNA secondary structure unwinding
DBV39_05260	COG0285	dihydrofolate synthase activity
DBV39_05290	COG0024	Methionine aminopeptidase
DBV39_05295	COG0052	Belongs to the universal ribosomal protein uS2 family
DBV39_05300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DBV39_05305	COG0528	UMP kinase activity
DBV39_05310	COG0233	cytoplasmic translational termination
DBV39_05315	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DBV39_05325	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DBV39_05330	COG0750	zinc metalloprotease
DBV39_05345	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DBV39_05350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DBV39_05355	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DBV39_05360	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DBV39_05365	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DBV39_05370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBV39_05385	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DBV39_05390	COG2867	negative regulation of translational initiation
DBV39_05395	COG2914	Belongs to the UPF0125 (RnfH) family
DBV39_05400	COG1024	Enoyl-CoA hydratase
DBV39_05410	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DBV39_05415	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DBV39_05425	COG0084	hydrolase, TatD family'
DBV39_05445	COG0625	glutathione transferase activity
DBV39_05450	COG0386	Belongs to the glutathione peroxidase family
DBV39_05455	COG0415	Belongs to the DNA photolyase family
DBV39_05460	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DBV39_05470	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DBV39_05475	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DBV39_05500	COG0473	3-isopropylmalate dehydrogenase activity
DBV39_05510	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DBV39_05515	COG0783	Belongs to the Dps family
DBV39_05520	COG0583	DNA-binding transcription factor activity
DBV39_05525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DBV39_05535	COG1840	ABC-type Fe3 transport system, periplasmic component
DBV39_05545	COG3842	ATPase activity
DBV39_05555	COG3852	Histidine kinase
DBV39_05560	COG0174	glutamine synthetase
DBV39_05565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DBV39_05570	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DBV39_05575	COG0583	DNA-binding transcription factor activity
DBV39_05585	COG1960	acyl-CoA dehydrogenase activity
DBV39_05630	COG2188	Transcriptional regulator
DBV39_05635	COG2030	dehydratase
DBV39_05640	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DBV39_05645	COG0405	Gamma-glutamyltransferase
DBV39_05650	COG1561	YicC-like family, N-terminal region
DBV39_05670	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_05675	COG0194	GDP metabolic process
DBV39_05680	COG1758	RNA polymerase activity
DBV39_05685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DBV39_05700	COG4067	protein conserved in archaea
DBV39_05700	COG0189	ligase activity
DBV39_05720	COG4181	ATPase activity
DBV39_05735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DBV39_05740	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DBV39_05745	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DBV39_05755	COG1187	pseudouridine synthase activity
DBV39_05760	COG3161	chorismate lyase activity
DBV39_05765	COG2814	Major facilitator Superfamily
DBV39_05785	COG0165	Argininosuccinate lyase
DBV39_05790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DBV39_05810	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DBV39_05815	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DBV39_05820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DBV39_05825	COG1619	proteins homologs of microcin C7 resistance protein MccF
DBV39_05830	COG0590	tRNA wobble adenosine to inosine editing
DBV39_05860	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DBV39_05865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DBV39_05880	COG0613	PHP domain protein
DBV39_05900	COG0084	hydrolase, TatD family'
DBV39_05905	COG1136	(ABC) transporter
DBV39_05920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DBV39_05925	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DBV39_05930	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_05935	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DBV39_05940	COG3622	Belongs to the hyi family
DBV39_05945	COG3836	Belongs to the HpcH HpaI aldolase family
DBV39_05950	COG0633	Ferredoxin
DBV39_05955	COG0443	Heat shock 70 kDa protein
DBV39_05960	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DBV39_05970	COG0822	iron-sulfur transferase activity
DBV39_05975	COG1104	cysteine desulfurase activity
DBV39_05985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DBV39_05990	COG0556	nucleotide-excision repair
DBV39_06015	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DBV39_06025	COG0740	serine-type endopeptidase activity
DBV39_06030	COG0544	peptidyl-prolyl cis-trans isomerase activity
DBV39_06040	COG0436	Aminotransferase
DBV39_06045	COG2171	N-acyltransferase activity
DBV39_06055	COG2890	protein-(glutamine-N5) methyltransferase activity
DBV39_06060	COG0488	(ABC) transporter
DBV39_06070	COG0210	DNA helicase
DBV39_06085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DBV39_06085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DBV39_06090	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DBV39_06095	COG0196	riboflavin kinase activity
DBV39_06100	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DBV39_06105	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DBV39_06110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DBV39_06115	COG0586	Pfam SNARE associated Golgi protein
DBV39_06120	COG0756	dUTP diphosphatase activity
DBV39_06125	COG0542	response to heat
DBV39_06130	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DBV39_06135	COG1278	Cold shock
DBV39_06145	COG0183	Belongs to the thiolase family
DBV39_06150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DBV39_06160	COG0811	peptide transport
DBV39_06165	COG0848	biopolymer transport protein
DBV39_06170	COG1663	tetraacyldisaccharide 4'-kinase activity
DBV39_06180	COG2835	tetraacyldisaccharide 4'-kinase activity
DBV39_06185	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DBV39_06190	COG0563	adenylate kinase activity
DBV39_06200	COG0728	peptidoglycan biosynthetic process
DBV39_06205	COG0268	Binds directly to 16S ribosomal RNA
DBV39_06215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBV39_06225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DBV39_06230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DBV39_06235	COG0137	argininosuccinate synthase activity
DBV39_06245	COG3447	MASE1 domain protein
DBV39_06245	COG5001	Diguanylate cyclase
DBV39_06245	COG5002	protein histidine kinase activity
DBV39_06250	COG0450	alkyl hydroperoxide reductase
DBV39_06255	COG1278	Cold shock
DBV39_06260	COG1024	Enoyl-CoA hydratase
DBV39_06280	COG0776	regulation of translation
DBV39_06285	COG0626	cystathionine gamma-synthase activity
DBV39_06290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBV39_06325	COG3384	dioxygenase
DBV39_06330	COG0583	DNA-binding transcription factor activity
DBV39_06350	COG1595	DNA-templated transcription, initiation
DBV39_06355	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DBV39_06370	COG1802	Transcriptional regulator
DBV39_06400	COG0154	amidase activity
DBV39_06420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DBV39_06425	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DBV39_06455	COG2084	Dehydrogenase
DBV39_06460	COG3447	MASE1 domain protein
DBV39_06460	COG5002	protein histidine kinase activity
DBV39_06460	COG5001	Diguanylate cyclase
DBV39_06495	COG4948	Mandelate Racemase Muconate Lactonizing
DBV39_06500	COG3181	Tripartite tricarboxylate transporter family receptor
DBV39_06505	COG2203	Gaf domain
DBV39_06505	COG3706	GGDEF domain
DBV39_06505	COG4251	negative regulation of phosphorylation
DBV39_06505	COG5001	Diguanylate cyclase
DBV39_06525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBV39_06535	COG1671	Belongs to the UPF0178 family
DBV39_06540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DBV39_06545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBV39_06550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DBV39_06565	COG0789	Transcriptional regulator
DBV39_06570	COG2119	membrane
DBV39_06580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DBV39_06585	COG3530	Putative quorum-sensing-regulated virulence factor
DBV39_06595	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DBV39_06600	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DBV39_06605	COG0720	synthase
DBV39_06610	COG0602	queuosine metabolic process
DBV39_06625	COG0069	glutamate synthase activity
DBV39_06645	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DBV39_06645	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DBV39_06650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBV39_06655	COG1126	abc transporter atp-binding protein
DBV39_06660	COG0765	amino acid transport
DBV39_06665	COG0765	amino acid transport
DBV39_06670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBV39_06675	COG5285	phytanoyl-CoA dioxygenase
DBV39_06680	COG1917	Cupin 2, conserved barrel domain protein
DBV39_06685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DBV39_06690	COG0456	acetyltransferase
DBV39_06780	COG1295	ribonuclease BN
DBV39_06800	COG0644	oxidoreductase
DBV39_06875	COG1490	D-aminoacyl-tRNA deacylase activity
DBV39_06880	COG2076	Multidrug Resistance protein
DBV39_06885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_06890	COG1960	acyl-CoA dehydrogenase activity
DBV39_06900	COG2721	sulfolactate sulfo-lyase activity
DBV39_06905	COG0431	NADPH-dependent FMN reductase
DBV39_06910	COG0583	DNA-binding transcription factor activity
DBV39_06915	COG1741	Belongs to the pirin family
DBV39_06920	COG3038	cytochrome b561
DBV39_06930	COG2353	YceI-like domain
DBV39_06945	COG3247	response to pH
DBV39_06965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DBV39_06980	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DBV39_06990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DBV39_06995	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DBV39_07000	COG0330	HflC and HflK could
DBV39_07005	COG0330	HflC and HflK could
DBV39_07010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DBV39_07015	COG1923	regulation of RNA biosynthetic process
DBV39_07020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DBV39_07030	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DBV39_07035	COG2976	Protein conserved in bacteria
DBV39_07040	COG0124	histidyl-tRNA synthetase
DBV39_07055	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DBV39_07060	COG0105	UTP biosynthetic process
DBV39_07065	COG0525	valine-tRNA ligase activity
DBV39_07070	COG0336	Belongs to the RNA methyltransferase TrmD family
DBV39_07075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DBV39_07080	COG0228	four-way junction DNA binding
DBV39_07090	COG0425	Belongs to the sulfur carrier protein TusA family
DBV39_07095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DBV39_07145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBV39_07200	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DBV39_07215	COG1252	NADH dehydrogenase
DBV39_07220	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DBV39_07245	COG0583	DNA-binding transcription factor activity
DBV39_07250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DBV39_07255	COG1960	acyl-CoA dehydrogenase activity
DBV39_07260	COG1960	acyl-CoA dehydrogenase activity
DBV39_07265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_07310	COG3278	Belongs to the heme-copper respiratory oxidase family
DBV39_07320	COG2217	Heavy metal translocating P-type atpase
DBV39_07325	COG2224	Isocitrate lyase
DBV39_07330	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DBV39_07330	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DBV39_07340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DBV39_07345	COG0322	excinuclease ABC activity
DBV39_07350	COG1472	Belongs to the glycosyl hydrolase 3 family
DBV39_07355	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DBV39_07370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBV39_07380	COG0318	PFAM AMP-dependent synthetase and ligase
DBV39_07385	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DBV39_07395	COG0254	rRNA binding
DBV39_07405	COG0534	Mate efflux family protein
DBV39_07410	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DBV39_07415	COG0501	Belongs to the peptidase M48B family
DBV39_07420	COG1162	GTPase activity
DBV39_07430	COG1360	Flagellar Motor Protein
DBV39_07440	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DBV39_07445	COG0335	large ribosomal subunit rRNA binding
DBV39_07450	COG0028	Belongs to the TPP enzyme family
DBV39_07455	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DBV39_07465	COG2358	TRAP transporter, solute receptor (TAXI family
DBV39_07490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBV39_07505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DBV39_07510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DBV39_07510	COG2169	Transcriptional regulator
DBV39_07545	COG1283	sodium-dependent phosphate transmembrane transporter activity
DBV39_07555	COG1414	Transcriptional regulator
DBV39_07575	COG1064	alcohol dehydrogenase
DBV39_07585	COG0506	proline dehydrogenase activity
DBV39_07585	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DBV39_07585	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DBV39_07600	COG4372	Transposase
DBV39_07645	COG0527	aspartate kinase activity
DBV39_07655	COG0037	tRNA processing
DBV39_07660	COG0825	malonyl-CoA metabolic process
DBV39_07670	COG0215	cysteine-tRNA ligase activity
DBV39_07680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DBV39_07685	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DBV39_07690	COG1968	undecaprenyl-diphosphatase activity
DBV39_07695	COG1253	flavin adenine dinucleotide binding
DBV39_07700	COG0483	inositol monophosphate 1-phosphatase activity
DBV39_07710	COG1045	serine acetyltransferase
DBV39_07715	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DBV39_07725	COG2200	EAL domain
DBV39_07735	COG2850	peptidyl-arginine hydroxylation
DBV39_07740	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DBV39_07745	COG0830	nickel cation binding
DBV39_07750	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DBV39_07755	COG0804	urea catabolic process
DBV39_07760	COG0832	Belongs to the urease beta subunit family
DBV39_07770	COG0831	urea catabolic process
DBV39_07775	COG0829	nickel cation binding
DBV39_07780	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DBV39_07785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DBV39_07790	COG1994	Peptidase M50
DBV39_07795	COG0009	L-threonylcarbamoyladenylate synthase
DBV39_07855	COG0028	Belongs to the TPP enzyme family
DBV39_07860	COG0436	Aminotransferase
DBV39_07865	COG0583	DNA-binding transcription factor activity
DBV39_07870	COG2301	Belongs to the HpcH HpaI aldolase family
DBV39_07880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_07885	COG2814	Major facilitator Superfamily
DBV39_07945	COG3181	Tripartite tricarboxylate transporter family receptor
DBV39_07950	COG0583	DNA-binding transcription factor activity
DBV39_07955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DBV39_07960	COG3385	transposase activity
DBV39_07970	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DBV39_07980	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DBV39_07985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBV39_07990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DBV39_08000	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DBV39_08005	COG0259	pyridoxamine-phosphate oxidase activity
DBV39_08010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DBV39_08030	COG1960	acyl-CoA dehydrogenase activity
DBV39_08035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_08040	COG0583	DNA-binding transcription factor activity
DBV39_08045	COG0028	Belongs to the TPP enzyme family
DBV39_08050	COG1960	acyl-CoA dehydrogenase activity
DBV39_08060	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DBV39_08065	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DBV39_08070	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DBV39_08090	COG0521	Mo-molybdopterin cofactor biosynthetic process
DBV39_08105	COG0126	phosphoglycerate kinase activity
DBV39_08110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DBV39_08115	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DBV39_08120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DBV39_08140	COG0436	Aminotransferase
DBV39_08145	COG0741	lytic transglycosylase activity
DBV39_08155	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DBV39_08180	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DBV39_08190	COG2027	D-alanyl-D-alanine carboxypeptidase
DBV39_08195	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DBV39_08200	COG0343	queuine tRNA-ribosyltransferase activity
DBV39_08205	COG1862	Preprotein translocase
DBV39_08210	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DBV39_08215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DBV39_08225	COG1702	phosphate starvation-inducible protein PhoH
DBV39_08230	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DBV39_08240	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DBV39_08245	COG1960	acyl-CoA dehydrogenase activity
DBV39_08295	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DBV39_08315	COG0678	peroxiredoxin activity
DBV39_08335	COG2091	lysine biosynthetic process via aminoadipic acid
DBV39_08355	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_08365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_08370	COG0154	amidase activity
DBV39_08380	COG0154	amidase activity
DBV39_08385	COG0625	glutathione transferase activity
DBV39_08395	COG0306	phosphate transporter
DBV39_08410	COG0123	including yeast histone deacetylase and acetoin utilization protein
DBV39_08435	COG1918	ferrous iron import across plasma membrane
DBV39_08435	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DBV39_08445	COG0655	NAD(P)H dehydrogenase (quinone) activity
DBV39_08485	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DBV39_08490	COG1047	Peptidyl-prolyl cis-trans
DBV39_08495	COG2003	Belongs to the UPF0758 family
DBV39_08500	COG0183	Belongs to the thiolase family
DBV39_08505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DBV39_08510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DBV39_08515	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DBV39_08520	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DBV39_08525	COG0495	leucyl-tRNA aminoacylation
DBV39_08535	COG1466	dna polymerase III delta subunit
DBV39_08540	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DBV39_08545	COG1981	membrane
DBV39_08575	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DBV39_08585	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DBV39_08590	COG0148	phosphopyruvate hydratase activity
DBV39_08595	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DBV39_08600	COG0504	CTP synthase activity
DBV39_08640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DBV39_08650	COG0791	NLP P60 protein
DBV39_08660	COG0583	DNA-binding transcription factor activity
DBV39_08670	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DBV39_08690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DBV39_08705	COG3284	Transcriptional regulator
DBV39_08710	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_08720	COG0318	PFAM AMP-dependent synthetase and ligase
DBV39_08735	COG0028	Belongs to the TPP enzyme family
DBV39_08740	COG1381	Involved in DNA repair and RecF pathway recombination
DBV39_08745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DBV39_08750	COG0571	ribonuclease III activity
DBV39_08755	COG0681	Belongs to the peptidase S26 family
DBV39_08765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DBV39_08785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DBV39_08790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBV39_08800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DBV39_08805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DBV39_08810	COG0416	fatty acid biosynthetic process
DBV39_08815	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DBV39_08820	COG1399	metal-binding, possibly nucleic acid-binding protein
DBV39_08830	COG0424	maF-like protein
DBV39_08840	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DBV39_08845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DBV39_08855	COG0564	pseudouridine synthase activity
DBV39_08860	COG1530	ribonuclease E activity
DBV39_08875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DBV39_08880	COG0159	tryptophan synthase activity
DBV39_08885	COG0133	tryptophan synthase activity
DBV39_08890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DBV39_08895	COG0251	oxidation-reduction process
DBV39_08915	COG2878	Part of a membrane complex involved in electron transport
DBV39_08920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DBV39_08925	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DBV39_08930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DBV39_08960	COG2154	pterin-4-alpha-carbinolamine dehydratase
DBV39_08975	COG0302	gtp cyclohydrolase
DBV39_08985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_08990	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_09000	COG1902	pentaerythritol trinitrate reductase activity
DBV39_09005	COG1666	GTP binding
DBV39_09010	COG3217	Mosc domain protein beta barrel domain protein
DBV39_09010	COG0633	Ferredoxin
DBV39_09015	COG0739	heme binding
DBV39_09025	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_09030	COG3243	poly(R)-hydroxyalkanoic acid synthase
DBV39_09040	COG0564	pseudouridine synthase activity
DBV39_09050	COG1199	ATP-dependent helicase activity
DBV39_09055	COG0180	Tryptophanyl-tRNA synthetase
DBV39_09060	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DBV39_09065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DBV39_09070	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBV39_09075	COG0567	Dehydrogenase, E1 component
DBV39_09080	COG0280	phosphate acetyltransferase
DBV39_09080	COG0281	malic enzyme
DBV39_09090	COG3436	PFAM IS66 Orf2 family protein
DBV39_09105	COG0372	Belongs to the citrate synthase family
DBV39_09110	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DBV39_09115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DBV39_09120	COG1053	succinate dehydrogenase
DBV39_09125	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DBV39_09135	COG2188	Transcriptional regulator
DBV39_09140	COG0039	L-malate dehydrogenase activity
DBV39_09170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DBV39_09175	COG2855	membrane
DBV39_09195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DBV39_09225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBV39_09230	COG0444	Belongs to the ABC transporter superfamily
DBV39_09235	COG4608	Belongs to the ABC transporter superfamily
DBV39_09240	COG4172	Belongs to the ABC transporter superfamily
DBV39_09265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBV39_09280	COG0412	Dienelactone hydrolase
DBV39_09290	COG2863	cytochrome
DBV39_09295	COG0446	pyridine nucleotide-disulphide oxidoreductase
DBV39_09305	COG1253	flavin adenine dinucleotide binding
DBV39_09310	COG3264	Mechanosensitive ion channel
DBV39_09310	COG1511	domain protein
DBV39_09325	COG1024	Enoyl-CoA hydratase
DBV39_09330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DBV39_09345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_09390	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DBV39_09395	COG0277	FAD linked oxidase domain protein
DBV39_09405	COG0583	DNA-binding transcription factor activity
DBV39_09410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DBV39_09425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBV39_09435	COG0765	amino acid transport
DBV39_09440	COG0765	amino acid transport
DBV39_09505	COG2003	Belongs to the UPF0758 family
DBV39_09510	COG4133	protoheme IX ABC transporter activity
DBV39_09530	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DBV39_09540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBV39_09545	COG3088	subunit of a heme lyase
DBV39_09550	COG4235	cytochrome complex assembly
DBV39_09555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBV39_09560	COG0785	Cytochrome C biogenesis protein
DBV39_09570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DBV39_09585	COG2124	cytochrome p450
DBV39_09590	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DBV39_09600	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DBV39_09610	COG2217	Heavy metal translocating P-type atpase
DBV39_09615	COG0789	Transcriptional regulator
DBV39_09625	COG0431	NADPH-dependent FMN reductase
DBV39_09635	COG0640	Transcriptional regulator
DBV39_09645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DBV39_09655	COG2217	Heavy metal translocating P-type atpase
DBV39_09685	COG4372	Transposase
DBV39_09695	COG3436	PFAM IS66 Orf2 family protein
DBV39_09785	COG3436	PFAM IS66 Orf2 family protein
DBV39_09820	COG1120	ATPase activity
DBV39_09845	COG1279	arginine transmembrane transporter activity
DBV39_09850	COG2808	Putative FMN-binding domain
DBV39_09955	COG0739	heme binding
DBV39_09980	COG2132	Multicopper oxidase
DBV39_09985	COG4232	protein-disulfide reductase activity
DBV39_09995	COG4133	protoheme IX ABC transporter activity
DBV39_10025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBV39_10030	COG3088	subunit of a heme lyase
DBV39_10035	COG4235	cytochrome complex assembly
DBV39_10065	COG0745	RESPONSE REGULATOR receiver
DBV39_10070	COG5002	protein histidine kinase activity
DBV39_10075	COG2132	Multicopper oxidase
DBV39_10080	COG0789	Transcriptional regulator
DBV39_10105	COG0583	DNA-binding transcription factor activity
DBV39_10120	COG4959	Type IV secretory pathway protease TraF
DBV39_10135	COG1192	Involved in chromosome partitioning
DBV39_10220	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DBV39_10225	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DBV39_10240	COG0402	S-adenosylhomocysteine deaminase activity
DBV39_10245	COG1218	3'(2'),5'-bisphosphate nucleotidase
DBV39_10255	COG2086	electron transfer activity
DBV39_10260	COG0123	including yeast histone deacetylase and acetoin utilization protein
DBV39_10280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBV39_10285	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DBV39_10290	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DBV39_10310	COG4372	Transposase
DBV39_10325	COG0776	regulation of translation
DBV39_10340	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DBV39_10350	COG0287	Prephenate dehydrogenase
DBV39_10355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DBV39_10365	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DBV39_10380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DBV39_10395	COG1268	BioY protein
DBV39_10405	COG1122	ATPase activity
DBV39_10410	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DBV39_10415	COG2917	probably involved in intracellular septation
DBV39_10425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DBV39_10430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DBV39_10440	COG1196	nuclear chromosome segregation
DBV39_10445	COG0477	Major facilitator Superfamily
DBV39_10450	COG1573	uracil-dna glycosylase
DBV39_10455	COG1214	PFAM Peptidase M22, glycoprotease
DBV39_10470	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DBV39_10475	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DBV39_10485	COG0560	Phosphoserine phosphatase
DBV39_10495	COG1007	ATP synthesis coupled electron transport
DBV39_10510	COG0713	ATP synthesis coupled electron transport
DBV39_10520	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DBV39_10525	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DBV39_10530	COG1034	ATP synthesis coupled electron transport
DBV39_10540	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DBV39_10545	COG0649	NAD binding
DBV39_10550	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DBV39_10555	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DBV39_10560	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DBV39_10570	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DBV39_10585	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DBV39_10590	COG0149	triose-phosphate isomerase activity
DBV39_10595	COG4221	oxidoreductase activity
DBV39_10595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBV39_10595	COG0604	alcohol dehydrogenase
DBV39_10595	COG3321	synthase
DBV39_10625	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DBV39_10630	COG0303	'Molybdopterin
DBV39_10645	COG0315	cyclic pyranopterin monophosphate synthase activity
DBV39_10655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DBV39_10665	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DBV39_10670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBV39_10710	COG3077	Addiction module antitoxin, RelB DinJ family
DBV39_10725	COG5001	Diguanylate cyclase
DBV39_10740	COG4988	ABC transporter
DBV39_10745	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DBV39_10755	COG1294	oxidase, subunit
DBV39_10765	COG0640	Transcriptional regulator
DBV39_10775	COG0252	asparaginase activity
DBV39_10790	COG1522	sequence-specific DNA binding
DBV39_10805	COG1185	polyribonucleotide nucleotidyltransferase activity
DBV39_10810	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DBV39_10825	COG1183	phosphatidylcholine synthase activity
DBV39_10835	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DBV39_10840	COG0440	acetolactate synthase activity
DBV39_10845	COG0028	Belongs to the TPP enzyme family
DBV39_10850	COG1289	transmembrane transporter activity
DBV39_10855	COG4689	acetoacetate decarboxylase
DBV39_10865	COG3022	response to hydroperoxide
DBV39_10895	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DBV39_10900	COG3657	addiction module killer protein
DBV39_10915	COG2159	amidohydrolase
DBV39_10935	COG2814	Major facilitator Superfamily
DBV39_11005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DBV39_11010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DBV39_11015	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DBV39_11025	COG1294	oxidase, subunit
DBV39_11030	COG1271	oxidase subunit
DBV39_11035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DBV39_11040	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DBV39_11045	COG1674	ftsk spoiiie
DBV39_11050	COG0492	ferredoxin-NADP+ reductase activity
DBV39_11060	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DBV39_11090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DBV39_11105	COG0612	Peptidase, M16
DBV39_11110	COG0484	heat shock protein binding
DBV39_11115	COG0443	Heat shock 70 kDa protein
DBV39_11120	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DBV39_11125	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DBV39_11130	COG1420	regulation of RNA biosynthetic process
DBV39_11140	COG0497	DNA recombination
DBV39_11145	COG0735	belongs to the Fur family
DBV39_11150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DBV39_11185	COG1021	2,3-dihydroxybenzoate-AMP ligase
DBV39_11205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBV39_11205	COG3433	isochorismatase activity
DBV39_11205	COG2226	methyltransferase
DBV39_11225	COG1132	(ABC) transporter
DBV39_11225	COG2375	cellular response to nickel ion
DBV39_11240	COG4771	TonB-dependent receptor
DBV39_11265	COG2814	Major facilitator Superfamily
DBV39_11285	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DBV39_11290	COG0167	dihydroorotate dehydrogenase activity
DBV39_11300	COG1414	Transcriptional regulator
DBV39_11305	COG1546	Belongs to the CinA family
DBV39_11305	COG1058	Belongs to the CinA family
DBV39_11335	COG0559	Belongs to the binding-protein-dependent transport system permease family
DBV39_11370	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DBV39_11375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBV39_11380	COG4558	Periplasmic binding protein
DBV39_11385	COG3720	iron ion transport
DBV39_11420	COG3158	transport of potassium into the cell
DBV39_11425	COG1739	Uncharacterized protein family UPF0029
DBV39_11460	COG1473	amidohydrolase
DBV39_11475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBV39_11480	COG0444	Belongs to the ABC transporter superfamily
DBV39_11485	COG4608	Belongs to the ABC transporter superfamily
DBV39_11495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DBV39_11510	COG1902	pentaerythritol trinitrate reductase activity
DBV39_11520	COG0546	phosphoglycolate phosphatase activity
DBV39_11540	COG4608	Belongs to the ABC transporter superfamily
DBV39_11555	COG1653	transport
DBV39_11565	COG0395	ABC-type sugar transport system, permease component
DBV39_11570	COG3842	ATPase activity
DBV39_11575	COG0584	glycerophosphoryl diester phosphodiesterase
DBV39_11585	COG0235	Class ii aldolase
DBV39_11600	COG0483	inositol monophosphate 1-phosphatase activity
DBV39_11605	COG0318	PFAM AMP-dependent synthetase and ligase
DBV39_11610	COG1473	amidohydrolase
DBV39_11615	COG2239	Acts as a magnesium transporter
DBV39_11625	COG1960	acyl-CoA dehydrogenase activity
DBV39_11630	COG1960	acyl-CoA dehydrogenase activity
DBV39_11635	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DBV39_11645	COG1280	lysine exporter protein (LysE YggA)
DBV39_11655	COG2828	Protein conserved in bacteria
DBV39_11675	COG0411	ABC transporter
DBV39_11700	COG3842	ATPase activity
DBV39_11705	COG1653	transport
DBV39_11725	COG1414	Transcriptional regulator
DBV39_11730	COG3706	GGDEF domain
DBV39_11740	COG0653	protein targeting
DBV39_11760	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DBV39_11765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DBV39_11775	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DBV39_11780	COG1181	Belongs to the D-alanine--D-alanine ligase family
DBV39_11785	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DBV39_11790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DBV39_11800	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DBV39_11805	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DBV39_11810	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DBV39_11820	COG3116	cell division
DBV39_11825	COG0275	rRNA processing
DBV39_11830	COG2001	Belongs to the MraZ family
DBV39_11840	COG0488	(ABC) transporter
DBV39_11845	COG0418	dihydroorotase activity
DBV39_11850	COG1473	amidohydrolase
DBV39_11890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DBV39_11900	COG0129	dihydroxy-acid dehydratase activity
DBV39_11930	COG2084	Dehydrogenase
DBV39_11935	COG0494	nUDIX hydrolase
DBV39_11940	COG0442	prolyl-tRNA aminoacylation
DBV39_11945	COG0824	Thioesterase
DBV39_11950	COG0811	peptide transport
DBV39_11965	COG0823	Involved in the tonB-independent uptake of proteins
DBV39_11990	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DBV39_12005	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DBV39_12010	COG1280	lysine exporter protein (LysE YggA)
DBV39_12025	COG0284	orotidine-5'-phosphate decarboxylase activity
DBV39_12035	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DBV39_12045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DBV39_12050	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DBV39_12080	COG0742	ribosomal rna small subunit methyltransferase
DBV39_12085	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DBV39_12090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DBV39_12110	COG1132	(ABC) transporter
DBV39_12115	COG2943	transferase activity, transferring hexosyl groups
DBV39_12130	COG0438	transferase activity, transferring glycosyl groups
DBV39_12135	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DBV39_12135	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DBV39_12145	COG2205	protein histidine kinase activity
DBV39_12150	COG0129	dihydroxy-acid dehydratase activity
DBV39_12155	COG0583	DNA-binding transcription factor activity
DBV39_12160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DBV39_12165	COG3002	Belongs to the UPF0753 family
DBV39_12170	COG0415	Belongs to the DNA photolyase family
DBV39_12175	COG3046	protein related to deoxyribodipyrimidine photolyase
DBV39_12185	COG2900	Belongs to the SlyX family
DBV39_12195	COG0012	GTP binding
DBV39_12200	COG0318	PFAM AMP-dependent synthetase and ligase
DBV39_12210	COG0193	aminoacyl-tRNA hydrolase activity
DBV39_12220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DBV39_12235	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DBV39_12245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DBV39_12250	COG0277	FAD linked oxidase domain protein
DBV39_12260	COG0166	Belongs to the GPI family
DBV39_12270	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DBV39_12275	COG1765	OsmC-like protein
DBV39_12285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DBV39_12290	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DBV39_12290	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DBV39_12295	COG0509	glycine decarboxylation via glycine cleavage system
DBV39_12300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DBV39_12310	COG2081	HI0933 family
DBV39_12320	COG0717	Belongs to the dCTP deaminase family
DBV39_12325	COG0489	protein tyrosine kinase activity
DBV39_12335	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DBV39_12335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DBV39_12340	COG1054	Belongs to the UPF0176 family
DBV39_12345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DBV39_12350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBV39_12360	COG1959	2 iron, 2 sulfur cluster binding
DBV39_12375	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DBV39_12380	COG0583	DNA-binding transcription factor activity
DBV39_12390	COG2272	Belongs to the type-B carboxylesterase lipase family
DBV39_12400	COG0604	alcohol dehydrogenase
DBV39_12425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DBV39_12430	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DBV39_12450	COG0326	Molecular chaperone. Has ATPase activity
DBV39_12455	COG0596	Alpha beta hydrolase
DBV39_12520	COG0288	reversible hydration of carbon dioxide
DBV39_12545	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DBV39_12610	COG1459	type II secretion system
DBV39_12615	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DBV39_12620	COG3119	arylsulfatase activity
DBV39_12625	COG1250	3-hydroxyacyl-CoA dehydrogenase
DBV39_12640	COG1024	Enoyl-CoA hydratase
DBV39_12650	COG1024	Enoyl-CoA hydratase
DBV39_12665	COG1126	abc transporter atp-binding protein
DBV39_12670	COG0765	amino acid transport
DBV39_12675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBV39_12700	COG0076	glutamate decarboxylase activity
DBV39_12705	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DBV39_12730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DBV39_12735	COG3228	Belongs to the MtfA family
DBV39_12780	COG0419	ATPase involved in DNA repair
DBV39_12785	COG0419	ATPase involved in DNA repair
DBV39_12790	COG0420	3'-5' exonuclease activity
DBV39_12800	COG2059	Chromate
DBV39_12820	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DBV39_12825	COG3639	organic phosphonate transmembrane transporter activity
DBV39_12830	COG3639	organic phosphonate transmembrane transporter activity
DBV39_12840	COG2133	pyrroloquinoline quinone binding
DBV39_12845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_12860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DBV39_12875	COG2079	MmgE PrpD family protein
DBV39_12885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DBV39_12890	COG1024	Enoyl-CoA hydratase
DBV39_12905	COG1940	carbohydrate kinase activity
DBV39_12910	COG1024	Enoyl-CoA hydratase
DBV39_12920	COG0412	Dienelactone hydrolase
DBV39_12925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DBV39_12940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DBV39_12965	COG0154	amidase activity
DBV39_12975	COG0142	geranyltranstransferase activity
DBV39_12980	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DBV39_12985	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DBV39_12990	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DBV39_12995	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DBV39_13025	COG2022	thiamine diphosphate biosynthetic process
DBV39_13030	COG0351	phosphomethylpyrimidine kinase
DBV39_13045	COG3181	Tripartite tricarboxylate transporter family receptor
DBV39_13055	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DBV39_13060	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DBV39_13070	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DBV39_13085	COG2226	methyltransferase
DBV39_13090	COG0745	RESPONSE REGULATOR receiver
DBV39_13105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DBV39_13110	COG1984	allophanate hydrolase subunit 2
DBV39_13125	COG1238	metal cluster binding
DBV39_13130	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DBV39_13130	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DBV39_13135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DBV39_13140	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DBV39_13150	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DBV39_13165	COG1137	ATPase activity
DBV39_13170	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DBV39_13185	COG1660	Displays ATPase and GTPase activities
DBV39_13200	COG1214	PFAM Peptidase M22, glycoprotease
DBV39_13200	COG0456	acetyltransferase
DBV39_13205	COG0288	reversible hydration of carbon dioxide
DBV39_13245	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DBV39_13260	COG3639	organic phosphonate transmembrane transporter activity
DBV39_13265	COG3639	organic phosphonate transmembrane transporter activity
DBV39_13270	COG2358	TRAP transporter, solute receptor (TAXI family
DBV39_13275	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DBV39_13280	COG1304	FMN binding
DBV39_13295	COG1136	(ABC) transporter
DBV39_13300	COG0628	permease
DBV39_13305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBV39_13310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DBV39_13315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DBV39_13320	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DBV39_13325	COG2967	ApaG domain
DBV39_13330	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DBV39_13335	COG0546	phosphoglycolate phosphatase activity
DBV39_13370	COG0583	DNA-binding transcription factor activity
DBV39_13380	COG4948	Mandelate Racemase Muconate Lactonizing
DBV39_13395	COG0179	Fumarylacetoacetate (FAA) hydrolase
DBV39_13415	COG0512	Glutamine amidotransferase of anthranilate synthase
DBV39_13420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DBV39_13425	COG0134	indole-3-glycerol-phosphate synthase activity
DBV39_13435	COG0640	Transcriptional regulator
DBV39_13455	COG2301	Belongs to the HpcH HpaI aldolase family
DBV39_13465	COG0513	Belongs to the DEAD box helicase family
DBV39_13495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DBV39_13500	COG1950	PFAM Membrane protein of
DBV39_13520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DBV39_13535	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DBV39_13545	COG1560	Kdo2-lipid A biosynthetic process
DBV39_13550	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DBV39_13560	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DBV39_13575	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
DBV39_13590	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DBV39_13605	COG0523	cobalamin synthesis protein
DBV39_13615	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DBV39_13620	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DBV39_13625	COG2096	Adenosyltransferase
DBV39_13630	COG1012	belongs to the aldehyde dehydrogenase family
DBV39_13650	COG4585	Histidine kinase
DBV39_13655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DBV39_13660	COG0321	lipoyl(octanoyl) transferase activity
DBV39_13675	COG1686	Belongs to the peptidase S11 family
DBV39_13695	COG1127	ABC transporter
DBV39_13700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DBV39_13705	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DBV39_13705	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DBV39_13710	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DBV39_13735	COG1024	Enoyl-CoA hydratase
DBV39_13740	COG2186	Transcriptional regulator
DBV39_13755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DBV39_13765	COG0662	Cupin 2, conserved barrel domain protein
DBV39_13765	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DBV39_13770	COG0583	DNA-binding transcription factor activity
DBV39_13785	COG1216	Glycosyl transferase, family 2
DBV39_13790	COG3568	Endonuclease Exonuclease Phosphatase
DBV39_13795	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DBV39_13810	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DBV39_13815	COG0154	amidase activity
DBV39_13830	COG1320	monovalent cation:proton antiporter activity
DBV39_13840	COG1006	Multisubunit Na H antiporter MnhC subunit
DBV39_13845	COG0651	ATP synthesis coupled electron transport
DBV39_13850	COG0651	ATP synthesis coupled electron transport
DBV39_13865	COG0651	ATP synthesis coupled electron transport
DBV39_13875	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DBV39_13880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DBV39_13890	COG0798	PFAM Bile acid sodium symporter
DBV39_13915	COG0583	DNA-binding transcription factor activity
DBV39_13920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBV39_13925	COG2814	Major facilitator Superfamily
DBV39_13940	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DBV39_13945	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DBV39_13950	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DBV39_13985	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DBV39_13990	COG1333	cytochrome c biogenesis protein
DBV39_14000	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DBV39_14010	COG2814	Major facilitator Superfamily
DBV39_14020	COG4232	protein-disulfide reductase activity
DBV39_14025	COG1324	tolerance protein
DBV39_14030	COG0203	ribosomal protein L17
DBV39_14035	COG0202	RNA polymerase activity
DBV39_14040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DBV39_14045	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DBV39_14050	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DBV39_14055	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DBV39_14060	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DBV39_14070	COG0200	Binds to the 23S rRNA
DBV39_14075	COG1841	ribosomal large subunit assembly
DBV39_14080	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DBV39_14085	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DBV39_14095	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DBV39_14100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DBV39_14105	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DBV39_14110	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DBV39_14115	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DBV39_14125	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DBV39_14130	COG0255	Belongs to the universal ribosomal protein uL29 family
DBV39_14135	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DBV39_14140	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DBV39_14145	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DBV39_14150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DBV39_14155	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DBV39_14160	COG0089	rRNA binding
DBV39_14165	COG0088	Forms part of the polypeptide exit tunnel
DBV39_14170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DBV39_14175	COG0051	transcription antitermination factor activity, RNA binding
DBV39_14180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DBV39_14185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DBV39_14190	COG0049	tRNA binding
DBV39_14200	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DBV39_14205	COG0085	RNA polymerase activity
DBV39_14210	COG0222	ribosome binding
DBV39_14215	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DBV39_14220	COG0081	regulation of translation
DBV39_14245	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DBV39_14265	COG1475	DNA binding
DBV39_14270	COG1192	Involved in chromosome partitioning
DBV39_14275	COG0357	Ribosomal RNA small subunit methyltransferase G
DBV39_14280	COG0445	tRNA wobble uridine modification
DBV39_14290	COG0436	Aminotransferase
DBV39_14305	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DBV39_14310	COG0706	membrane insertase activity
DBV39_14315	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DBV39_14325	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DBV39_14330	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DBV39_14345	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DBV39_14360	COG0732	type I restriction modification DNA specificity domain
DBV39_14365	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DBV39_14465	COG2808	Putative FMN-binding domain
DBV39_14470	COG1279	arginine transmembrane transporter activity
DBV39_14480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DBV39_14485	COG1061	Type III restriction enzyme res subunit
DBV39_14495	COG1002	Type II restriction enzyme, methylase subunits
DBV39_14600	COG1484	DNA-dependent DNA replication
DBV39_14625	COG1733	regulation of RNA biosynthetic process
DBV39_14630	COG0590	tRNA wobble adenosine to inosine editing
DBV39_14655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_14665	COG3181	Tripartite tricarboxylate transporter family receptor
DBV39_14690	COG0415	Belongs to the DNA photolyase family
DBV39_14695	COG0583	DNA-binding transcription factor activity
DBV39_14700	COG0427	acetyl-CoA hydrolase
DBV39_14725	COG2031	fatty acid transporter
DBV39_14730	COG2072	flavoprotein involved in K transport
DBV39_14740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DBV39_14755	COG0644	oxidoreductase
DBV39_14760	COG1840	ABC-type Fe3 transport system, periplasmic component
DBV39_14765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DBV39_14775	COG3842	ATPase activity
DBV39_14805	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DBV39_14830	COG0018	arginyl-trna synthetase
DBV39_14855	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DBV39_14865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DBV39_14895	COG2833	Protein of unknown function (DUF455)
DBV39_14900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DBV39_14910	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DBV39_14920	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DBV39_14940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBV39_14945	COG4948	Mandelate Racemase Muconate Lactonizing
DBV39_14950	COG0277	FAD linked oxidase domain protein
DBV39_14970	COG2808	Putative FMN-binding domain
DBV39_15000	COG2308	Evidence 4 Homologs of previously reported genes of
DBV39_15010	COG0477	Major facilitator Superfamily
DBV39_15020	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DBV39_15025	COG0513	Belongs to the DEAD box helicase family
DBV39_15030	COG3118	belongs to the thioredoxin family
DBV39_15030	COG0457	Tetratricopeptide repeat
DBV39_15075	COG0457	Tetratricopeptide repeat
DBV39_15080	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DBV39_15085	COG1215	transferase activity, transferring glycosyl groups
DBV39_15090	COG1215	transferase activity, transferring glycosyl groups
DBV39_15095	COG1215	transferase activity, transferring glycosyl groups
DBV39_15100	COG0489	protein tyrosine kinase activity
DBV39_15125	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DBV39_15140	COG0583	DNA-binding transcription factor activity
DBV39_15145	COG3181	Tripartite tricarboxylate transporter family receptor
DBV39_15150	COG0154	amidase activity
DBV39_15185	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_15190	COG0583	DNA-binding transcription factor activity
DBV39_15195	COG1024	Enoyl-CoA hydratase
DBV39_15205	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DBV39_15265	COG0154	amidase activity
DBV39_15290	COG4372	Transposase
DBV39_15335	COG4172	Belongs to the ABC transporter superfamily
DBV39_15345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBV39_15350	COG0747	negative chemotaxis
DBV39_15370	COG2969	positive regulation of protein catabolic process
DBV39_15375	COG0625	glutathione transferase activity
DBV39_15380	COG2857	Cytochrome c1
DBV39_15385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DBV39_15395	COG1970	mechanosensitive ion channel activity
DBV39_15400	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DBV39_15410	COG0583	DNA-binding transcription factor activity
DBV39_15415	COG0805	protein transport
DBV39_15420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DBV39_15425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DBV39_15430	COG0537	adenosine 5'-monophosphoramidase activity
DBV39_15435	COG0140	phosphoribosyl-ATP diphosphatase activity
DBV39_15440	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DBV39_15445	COG0107	imidazoleglycerol-phosphate synthase activity
DBV39_15450	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DBV39_15460	COG0131	Imidazoleglycerol-phosphate dehydratase
DBV39_15465	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DBV39_15470	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DBV39_15475	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DBV39_15485	COG0842	Transport permease protein
DBV39_15490	COG1131	(ABC) transporter
DBV39_15505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DBV39_15510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DBV39_15515	COG1127	ABC transporter
DBV39_15525	COG0070	glutamate synthase
DBV39_15525	COG0069	glutamate synthase activity
DBV39_15525	COG0067	glutamate synthase
DBV39_15535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DBV39_15555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DBV39_15595	COG1999	signal sequence binding
DBV39_15610	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DBV39_15615	COG2814	Major facilitator Superfamily
DBV39_15645	COG3273	potassium ion transport
DBV39_15645	COG0471	metal ion transport
DBV39_15655	COG1012	belongs to the aldehyde dehydrogenase family
DBV39_15670	COG0604	alcohol dehydrogenase
DBV39_15715	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DBV39_15720	COG1132	(ABC) transporter
DBV39_15730	COG0038	chloride channel
DBV39_15780	COG1136	(ABC) transporter
DBV39_15815	COG2304	oxidoreductase activity
DBV39_15830	COG2205	protein histidine kinase activity
DBV39_15830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBV39_15835	COG4999	Histidine kinase
DBV39_15835	COG3850	Histidine kinase
DBV39_15835	COG3437	response regulator, receiver
DBV39_15835	COG2205	protein histidine kinase activity
DBV39_15875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DBV39_15885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DBV39_15895	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_15910	COG3386	PFAM SMP-30 Gluconolaconase
DBV39_15925	COG1053	succinate dehydrogenase
DBV39_15930	COG0583	DNA-binding transcription factor activity
DBV39_15940	COG3174	membrane
DBV39_15945	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DBV39_15960	COG0242	peptide deformylase activity
DBV39_15965	COG0668	transmembrane transport
DBV39_15970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DBV39_15975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DBV39_15980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DBV39_15980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DBV39_15990	COG5000	phosphorelay sensor kinase activity
DBV39_15995	COG2204	response regulator
DBV39_16000	COG0569	domain protein
DBV39_16010	COG0730	response to heat
DBV39_16020	COG2226	methyltransferase
DBV39_16035	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DBV39_16040	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DBV39_16045	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DBV39_16055	COG0588	phosphoglycerate mutase activity
DBV39_16060	COG4942	peptidase
DBV39_16065	COG0793	Belongs to the peptidase S41A family
DBV39_16070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DBV39_16075	COG0546	phosphoglycolate phosphatase activity
DBV39_16080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DBV39_16090	COG2823	Periplasmic or secreted lipoprotein
DBV39_16095	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DBV39_16100	COG1115	amino acid carrier protein
DBV39_16105	COG1802	Transcriptional regulator
DBV39_16110	COG0596	Alpha beta hydrolase
DBV39_16125	COG0438	transferase activity, transferring glycosyl groups
DBV39_16135	COG0438	transferase activity, transferring glycosyl groups
DBV39_16140	COG0438	transferase activity, transferring glycosyl groups
DBV39_16160	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DBV39_16220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DBV39_16235	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DBV39_16240	COG0066	3-isopropylmalate dehydratase activity
DBV39_16260	COG1335	isochorismatase
DBV39_16280	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBV39_16320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DBV39_16325	COG1278	Cold shock
DBV39_16345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DBV39_16350	COG2890	protein-(glutamine-N5) methyltransferase activity
DBV39_16355	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DBV39_16365	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_16370	COG0037	tRNA processing
DBV39_16390	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DBV39_16410	COG0356	it plays a direct role in the translocation of protons across the membrane
DBV39_16425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DBV39_16430	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DBV39_16435	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DBV39_16440	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DBV39_16445	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DBV39_16455	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DBV39_16460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DBV39_16465	COG0210	DNA helicase
DBV39_16475	COG1250	3-hydroxyacyl-CoA dehydrogenase
DBV39_16480	COG3245	cytochrome
DBV39_16490	COG2918	glutathione biosynthetic process
DBV39_16500	COG2771	luxR family
DBV39_16505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DBV39_16515	COG2223	nitrite transmembrane transporter activity
DBV39_16525	COG0708	Exodeoxyribonuclease III
DBV39_16530	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DBV39_16535	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DBV39_16540	COG0154	amidase activity
DBV39_16545	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DBV39_16550	COG1077	Cell shape determining protein MreB Mrl
DBV39_16555	COG1792	Involved in formation and maintenance of cell shape
DBV39_16565	COG0768	penicillin binding
DBV39_16570	COG0772	Belongs to the SEDS family
DBV39_16580	COG2177	Part of the ABC transporter FtsEX involved in
DBV39_16585	COG2884	Cell division ATP-binding protein ftsE
DBV39_16590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBV39_16595	COG4597	amino acid ABC transporter
DBV39_16600	COG0765	amino acid transport
DBV39_16605	COG1126	abc transporter atp-binding protein
DBV39_16630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DBV39_16635	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DBV39_16645	COG2261	transglycosylase associated protein
DBV39_16675	COG1136	(ABC) transporter
DBV39_16685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBV39_16695	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DBV39_16705	COG4942	peptidase
DBV39_16725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_16735	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DBV39_16740	COG2011	ABC-type metal ion transport system permease component
DBV39_16785	COG5002	protein histidine kinase activity
DBV39_16815	COG0154	amidase activity
DBV39_16835	COG2233	PERMEase
DBV39_16855	COG0667	Aldo Keto reductase
DBV39_16860	COG2094	Belongs to the DNA glycosylase MPG family
DBV39_16870	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DBV39_16880	COG0668	transmembrane transport
DBV39_16890	COG2203	Gaf domain
DBV39_16890	COG5001	Diguanylate cyclase
DBV39_16890	COG3706	GGDEF domain
DBV39_16890	COG4251	negative regulation of phosphorylation
DBV39_16905	COG0659	secondary active sulfate transmembrane transporter activity
DBV39_16925	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DBV39_16930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DBV39_16950	COG0237	dephospho-CoA kinase activity
DBV39_16955	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
DBV39_16965	COG0494	nUDIX hydrolase
DBV39_16975	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DBV39_16980	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DBV39_16985	COG0352	thiamine-phosphate diphosphorylase activity
DBV39_16995	COG1773	rubredoxin
DBV39_17000	COG1678	Uncharacterized ACR, COG1678
DBV39_17005	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DBV39_17010	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DBV39_17015	COG0540	Belongs to the ATCase OTCase family
DBV39_17030	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DBV39_17040	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DBV39_17050	COG0557	exoribonuclease II activity
DBV39_17055	COG3150	esterase
DBV39_17060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DBV39_17065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBV39_17070	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DBV39_17075	COG0511	ligase activity, forming carbon-carbon bonds
DBV39_17080	COG0439	Biotin carboxylase
DBV39_17085	COG2264	protein methyltransferase activity
DBV39_17095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBV39_17105	COG0762	integral membrane protein
DBV39_17135	COG0400	carboxylic ester hydrolase activity
DBV39_17145	COG0312	modulator of DNA gyrase
DBV39_17150	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DBV39_17155	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DBV39_17160	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DBV39_17165	COG0531	amino acid
DBV39_17170	COG0316	Belongs to the HesB IscA family
DBV39_17180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DBV39_17190	COG0745	RESPONSE REGULATOR receiver
DBV39_17195	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DBV39_17200	COG0739	heme binding
DBV39_17205	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DBV39_17210	COG1881	PFAM PEBP family protein
DBV39_17220	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DBV39_17225	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DBV39_17230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DBV39_17230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DBV39_17245	COG0582	viral genome integration into host DNA
DBV39_17270	COG0028	Belongs to the TPP enzyme family
DBV39_17275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBV39_17280	COG3181	Tripartite tricarboxylate transporter family receptor
DBV39_17310	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_17315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DBV39_17355	COG0656	L-ascorbic acid biosynthetic process
DBV39_17400	COG2181	nitrate reductase activity
DBV39_17405	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DBV39_17410	COG1140	nitrate reductase beta subunit
DBV39_17415	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DBV39_17420	COG2223	nitrite transmembrane transporter activity
DBV39_17430	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DBV39_17435	COG0288	reversible hydration of carbon dioxide
DBV39_17440	COG1763	Mo-molybdopterin cofactor biosynthetic process
DBV39_17445	COG3850	Histidine kinase
DBV39_17445	COG3850	Histidine kinase
DBV39_17450	COG2197	response regulator
DBV39_17455	COG0303	'Molybdopterin
DBV39_17460	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DBV39_17465	COG0314	molybdopterin synthase activity
DBV39_17470	COG0746	molybdenum cofactor guanylyltransferase activity
DBV39_17490	COG2070	2-Nitropropane dioxygenase
DBV39_17495	COG3945	hemerythrin HHE cation binding domain
DBV39_17500	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DBV39_17505	COG3604	Transcriptional regulator
DBV39_17515	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_17535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBV39_17540	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DBV39_17555	COG3706	GGDEF domain
DBV39_17585	COG1960	acyl-CoA dehydrogenase activity
DBV39_17590	COG0318	PFAM AMP-dependent synthetase and ligase
DBV39_17610	COG1024	Enoyl-CoA hydratase
DBV39_17615	COG2267	carboxylic ester hydrolase activity
DBV39_17620	COG1024	Enoyl-CoA hydratase
DBV39_17625	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DBV39_17630	COG1687	branched-chain amino acid
DBV39_17635	COG2175	clavaminate synthase activity
DBV39_17655	COG0473	3-isopropylmalate dehydrogenase activity
DBV39_17660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DBV39_17670	COG1027	Aspartate ammonia-lyase
DBV39_17680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DBV39_17690	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DBV39_17695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DBV39_17700	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DBV39_17705	COG1929	Belongs to the glycerate kinase type-1 family
DBV39_17710	COG0700	Nucleoside recognition
DBV39_17725	COG0204	Acyl-transferase
DBV39_17730	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DBV39_17735	COG0751	glycine-tRNA ligase activity
DBV39_17740	COG0752	glycyl-tRNA synthetase alpha subunit
DBV39_17755	COG1294	oxidase, subunit
DBV39_17770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_17775	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_17780	COG1960	acyl-CoA dehydrogenase activity
DBV39_17785	COG1960	acyl-CoA dehydrogenase activity
DBV39_17790	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
DBV39_17800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DBV39_17805	COG0617	tRNA 3'-terminal CCA addition
DBV39_17815	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DBV39_17820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DBV39_17825	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DBV39_17830	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DBV39_17835	COG0860	N-Acetylmuramoyl-L-alanine amidase
DBV39_17840	COG0802	atpase or kinase
DBV39_17850	COG4974	Belongs to the 'phage' integrase family
DBV39_17870	COG1074	ATP-dependent DNA helicase activity
DBV39_17895	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DBV39_17915	COG0505	Belongs to the CarA family
DBV39_17920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DBV39_17925	COG0300	oxidoreductase activity
DBV39_17935	COG1309	transcriptional regulator
DBV39_17945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DBV39_17950	COG1534	Rna-binding protein
DBV39_17955	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DBV39_17960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DBV39_17970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DBV39_17985	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DBV39_17995	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DBV39_18000	COG3842	ATPase activity
DBV39_18005	COG1176	ABC-type spermidine putrescine transport system, permease component I
DBV39_18010	COG1178	ABC-type Fe3 transport system permease component
DBV39_18015	COG0402	S-adenosylhomocysteine deaminase activity
DBV39_18040	COG0859	PFAM glycosyl transferase family 9
DBV39_18045	COG0463	Glycosyl transferase, family 2
DBV39_18050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DBV39_18065	COG4608	Belongs to the ABC transporter superfamily
DBV39_18070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBV39_18075	COG0601	transmembrane transport
DBV39_18080	COG0747	negative chemotaxis
DBV39_18105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DBV39_18115	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DBV39_18120	COG3842	ATPase activity
DBV39_18125	COG1176	ABC-type spermidine putrescine transport system, permease component I
DBV39_18160	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DBV39_18165	COG2894	cell division
DBV39_18170	COG0850	regulation of cytokinetic process
DBV39_18175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DBV39_18185	COG1294	oxidase, subunit
DBV39_18215	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DBV39_18220	COG0668	transmembrane transport
DBV39_18230	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DBV39_18240	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DBV39_18250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DBV39_18260	COG0006	proline dipeptidase activity
DBV39_18270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DBV39_18285	COG2814	Major facilitator Superfamily
DBV39_18295	COG0429	hydrolase of the alpha beta-hydrolase fold
DBV39_18320	COG0513	Belongs to the DEAD box helicase family
DBV39_18325	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DBV39_18335	COG1802	Transcriptional regulator
DBV39_18370	COG0531	amino acid
DBV39_18375	COG2264	protein methyltransferase activity
DBV39_18400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBV39_18405	COG0583	DNA-binding transcription factor activity
DBV39_18415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DBV39_18465	COG1335	isochorismatase
DBV39_18490	COG3108	Peptidase M15
DBV39_18510	COG2828	Protein conserved in bacteria
DBV39_18515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DBV39_18525	COG0573	inorganic phosphate transmembrane transporter activity
DBV39_18530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DBV39_18540	COG0668	transmembrane transport
DBV39_18550	COG0778	Nitroreductase
DBV39_18565	COG1752	Esterase of the alpha-beta hydrolase superfamily
DBV39_18570	COG1177	transmembrane transport
DBV39_18575	COG1176	ABC-type spermidine putrescine transport system, permease component I
DBV39_18605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DBV39_18610	COG2816	NAD+ diphosphatase activity
DBV39_18625	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DBV39_18635	COG0517	IMP dehydrogenase activity
DBV39_18635	COG0617	tRNA 3'-terminal CCA addition
DBV39_18635	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DBV39_18645	COG2814	Major facilitator Superfamily
DBV39_18650	COG1024	Enoyl-CoA hydratase
DBV39_18660	COG1024	Enoyl-CoA hydratase
DBV39_18675	COG2205	protein histidine kinase activity
DBV39_18690	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
DBV39_18690	COG0028	Belongs to the TPP enzyme family
DBV39_18725	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_18730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DBV39_18735	COG0517	IMP dehydrogenase activity
DBV39_18735	COG4175	Glycine betaine
DBV39_18740	COG4176	ABC-type proline glycine betaine transport system permease component
DBV39_18765	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DBV39_18770	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DBV39_18770	COG3608	succinylglutamate desuccinylase aspartoacylase
DBV39_18780	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_18785	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_18790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBV39_18795	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DBV39_18800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DBV39_18810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DBV39_18815	COG1560	Kdo2-lipid A biosynthetic process
DBV39_18840	COG0697	spore germination
DBV39_18845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_18850	COG1024	Enoyl-CoA hydratase
DBV39_18865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBV39_18870	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DBV39_18875	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_18900	COG5265	(ABC) transporter
DBV39_18915	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_18920	COG0490	domain, Protein
DBV39_18920	COG0471	metal ion transport
DBV39_18925	COG2130	NADP-dependent
DBV39_18930	COG4864	UPF0365 protein
DBV39_18940	COG1024	Enoyl-CoA hydratase
DBV39_18950	COG4864	UPF0365 protein
DBV39_18955	COG1030	water channel activity
DBV39_18980	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
DBV39_18985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DBV39_18990	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DBV39_19000	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_19010	COG0318	PFAM AMP-dependent synthetase and ligase
DBV39_19015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DBV39_19045	COG1028	Short-chain dehydrogenase reductase Sdr
DBV39_19060	COG0154	amidase activity
DBV39_19070	COG0659	secondary active sulfate transmembrane transporter activity
DBV39_19075	COG0402	S-adenosylhomocysteine deaminase activity
DBV39_19100	COG1872	DUF167
DBV39_19110	COG1388	LysM domain
DBV39_19110	COG0741	lytic transglycosylase activity
DBV39_19115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DBV39_19120	COG2226	methyltransferase
DBV39_19130	COG0328	RNA-DNA hybrid ribonuclease activity
DBV39_19135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBV39_19140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DBV39_19155	COG4974	Belongs to the 'phage' integrase family
DBV39_19205	COG0629	single-stranded DNA binding