locus-tag	class	description
AO498_00015	ENOG4105CK5	oxidoreductase
AO498_00020	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AO498_00025	ENOG4105CN9	Peptidase m42 family protein
AO498_00035	ENOG4107QX3	carboxylase
AO498_00040	ENOG4105C9X	ppx gppa phosphatase
AO498_00060	ENOG4105F32	YngK protein
AO498_00075	ENOG4105D17	glycoside hydrolase, family 3 domain protein
AO498_00090	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AO498_00105	ENOG4105C5H	ABC transporter
AO498_00120	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AO498_00145	ENOG4105W5Q	DNA repair protein (RadC
AO498_00150	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
AO498_00160	ENOG4105CHM	Aminotransferase
AO498_00185	ENOG4105C5H	ABC transporter
AO498_00200	ENOG4105DY9	regulatoR
AO498_00205	ENOG4108HRK	Histidine kinase
AO498_00215	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AO498_00220	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AO498_00225	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AO498_00230	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AO498_00240	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AO498_00245	ENOG4105BZU	Histidine kinase
AO498_00260	ENOG4105EI2	Pseudouridine synthase
AO498_00270	ENOG4108UJD	30S ribosomal protein S9
AO498_00275	ENOG4105CE9	30S ribosomal protein S2
AO498_00280	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AO498_00285	ENOG4107RAQ	aminopeptidase
AO498_00290	ENOG4105C1V	Peptidase, M16
AO498_00300	ENOG4107X35	defense response to bacterium
AO498_00315	ENOG4105C6E	dna polymerase iii
AO498_00350	ENOG4105BZU	Histidine kinase
AO498_00365	ENOG4105CN1	protease
AO498_00375	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AO498_00380	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AO498_00385	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AO498_00390	ENOG4105E9K	Isocitrate dehydrogenase
AO498_00410	ENOG41061MV	Arylsulfatase
AO498_00450	ENOG4105W2Z	cytochrome C, class I
AO498_00465	ENOG4105EAA	nucleoside
AO498_00500	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AO498_00520	ENOG4105BZ1	(ABC) transporter
AO498_00530	ENOG4105C0P	Mg chelatase subunit ChlI
AO498_00565	ENOG4105CSR	polyphosphate kinase 2
AO498_00570	ENOG4105C26	Dehydrogenase
AO498_00600	ENOG4105CHM	Aminotransferase
AO498_00615	ENOG41080R2	UPF0102 protein
AO498_00620	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AO498_00635	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AO498_00650	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
AO498_00655	ENOG4105K46	50S ribosomal protein l27
AO498_00660	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AO498_00665	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AO498_00670	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AO498_00690	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AO498_00695	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AO498_00700	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AO498_00705	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AO498_00715	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AO498_00720	ENOG4105CAT	Cytidine monophosphate kinase
AO498_00725	ENOG4105CPN	adenine deaminase
AO498_00730	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AO498_00740	ENOG4105RHA	ABC transporter, permease
AO498_00745	ENOG4108IUX	(ABC) transporter
AO498_00755	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AO498_00760	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AO498_00765	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AO498_00770	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AO498_00775	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AO498_00785	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
AO498_00790	ENOG4105UYK	outer membrane protein a
AO498_00795	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AO498_00820	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AO498_00825	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AO498_00835	ENOG4105C1J	atp-dependent rna helicase
AO498_00840	ENOG4105CD3	dihydroorotase
AO498_00855	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AO498_00870	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AO498_00875	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AO498_00880	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AO498_00885	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AO498_00895	ENOG4105FGM	Fructosamine kinase
AO498_00910	ENOG4105CFH	Aspartokinase
AO498_00915	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AO498_00925	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AO498_00945	ENOG4105DT9	hydrolase family 43
AO498_00950	ENOG4105D98	threonine synthase
AO498_00955	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AO498_00960	ENOG4105CFH	Aspartokinase
AO498_00985	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AO498_00990	ENOG4107RJ1	sodium solute
AO498_01000	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AO498_01020	ENOG410667J	hydrolase
AO498_01025	ENOG4105DA4	cytochrome c-type biogenesis protein
AO498_01045	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AO498_01070	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AO498_01080	ENOG4105D17	glycoside hydrolase, family 3 domain protein
AO498_01090	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
AO498_01100	ENOG4105DF6	Fe-S oxidoreductase
AO498_01105	ENOG4105DF6	Fe-S oxidoreductase
AO498_01115	ENOG4105EMN	RNA polymerase sigma factor
AO498_01165	ENOG4107RWR	Sodium hydrogen exchanger
AO498_01170	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AO498_01175	ENOG4105DJ2	Major Facilitator Superfamily
AO498_01180	ENOG4108U5N	UPF0316 protein
AO498_01185	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
AO498_01210	ENOG4105KG3	cytidine deaminase
AO498_01235	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AO498_01240	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AO498_01250	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AO498_01255	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AO498_01260	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AO498_01265	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AO498_01275	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
AO498_01280	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AO498_01305	ENOG4105CPK	Glycosyl transferase (Group 1
AO498_01310	ENOG4105DC7	peptidase M24
AO498_01345	ENOG41061MV	Arylsulfatase
AO498_01350	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AO498_01355	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AO498_01360	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AO498_01365	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
AO498_01370	ENOG410842R	atp synthase
AO498_01375	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AO498_01395	ENOG4108JQC	penicillin-binding protein 1A
AO498_01400	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AO498_01420	ENOG4105E6M	Sulphatase-modifying factor protein
AO498_01445	ENOG4105CSA	Coproporphyrinogen iii oxidase
AO498_01460	ENOG4105WN5	stage II sporulation protein
AO498_01470	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AO498_01475	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AO498_01485	ENOG4105BZ1	(ABC) transporter
AO498_01495	ENOG4105M7K	Involved in the transcription termination process (By similarity)
AO498_01510	ENOG4105VIE	preprotein translocase, subunit YajC
AO498_01530	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AO498_01555	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AO498_01565	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AO498_01570	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AO498_01590	ENOG4105FE9	pseudouridine synthase
AO498_01595	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AO498_01620	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AO498_01625	ENOG4105D22	carbon starvation protein
AO498_01650	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AO498_01655	ENOG4105CHV	Transcription elongation factor NusA
AO498_01660	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
AO498_01670	ENOG4105DFF	Rod shape-determining protein mreb
AO498_01675	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AO498_01690	ENOG4105CNI	cell division protein FtsW
AO498_01705	ENOG4107T8J	thymidine kinase
AO498_01710	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
AO498_01715	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AO498_01770	ENOG4105C34	Pseudouridine synthase
AO498_01785	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AO498_01800	ENOG4105C6Z	Gluconate
AO498_01810	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AO498_01820	ENOG4105BZS	acriflavin resistance protein
AO498_01830	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AO498_01835	ENOG4108KPZ	tonB-dependent Receptor
AO498_01845	ENOG4105C9M	aspartyl-trna synthetase
AO498_01850	ENOG4105DR5	peptidase
AO498_01855	ENOG4105FE9	pseudouridine synthase
AO498_01860	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AO498_01905	ENOG4105C03	ribonuclease
AO498_01915	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AO498_01925	ENOG4108UUM	single-stranded DNA-binding protein
AO498_01930	ENOG4108JU5	Magnesium and cobalt efflux protein
AO498_01950	ENOG4105CEP	NADH dehydrogenase
AO498_01955	ENOG4105CDY	transcriptional regulatory protein
AO498_01960	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AO498_01975	ENOG4105CMQ	Chloride channel
AO498_01980	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AO498_01985	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AO498_02005	ENOG4105CUZ	uba thif-type nad fad binding protein
AO498_02045	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AO498_02065	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AO498_02070	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AO498_02075	ENOG4105SFS	phosphoesterase RecJ domain protein
AO498_02080	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AO498_02100	ENOG4105C27	TonB-dependent Receptor Plug
AO498_02110	ENOG4105Q9Y	Universal stress protein
AO498_02130	ENOG4105BZ1	(ABC) transporter
AO498_02150	ENOG4105D60	lipoprotein releasing system transmembrane protein
AO498_02155	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AO498_02175	ENOG4108YZG	isomerase
AO498_02180	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AO498_02185	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AO498_02205	ENOG4105ECY	inositol monophosphatase
AO498_02215	ENOG4105KZX	Pterin carbinolamine dehydratase
AO498_02230	ENOG4105C37	(CBS) domain
AO498_02255	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AO498_02280	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AO498_02290	ENOG4105E2X	shikimate dehydrogenase
AO498_02300	ENOG41061P3	phosphosulfolactate synthase
AO498_02315	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
AO498_02330	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AO498_02345	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AO498_02350	ENOG4108ZGC	gaf domain protein
AO498_02360	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AO498_02365	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AO498_02375	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AO498_02380	ENOG4105EYW	Ion transport protein
AO498_02385	ENOG4107R4J	Chloride channel
AO498_02440	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
AO498_02505	ENOG4105EN6	Membrane
AO498_02510	ENOG4108JYZ	YitT family
AO498_02530	ENOG4105D49	3-dehydroquinate synthase
AO498_02535	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AO498_02540	ENOG4105F8V	Hydrolase, tatD family
AO498_02550	ENOG4108UW5	maltose o-acetyltransferase
AO498_02570	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AO498_02585	ENOG4105FQP	Beta-lactamase
AO498_02600	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
AO498_02620	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AO498_02625	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AO498_02650	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AO498_02655	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AO498_02660	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AO498_02680	ENOG4105VJY	transcriptional regulator
AO498_02685	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AO498_02705	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AO498_02710	ENOG4108YYS	metal-dependent hydrolase (By similarity)
AO498_02730	ENOG4105CGK	Exodeoxyribonuclease III
AO498_02740	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AO498_02745	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AO498_02760	ENOG4108IQE	Amp-dependent synthetase and ligase
AO498_02775	ENOG4105CHU	acetyl-coa acetyltransferase
AO498_02780	ENOG4105C1G	acyl-Coa dehydrogenase
AO498_02785	ENOG4105BZU	Histidine kinase
AO498_02790	ENOG4105EQD	regulatoR
AO498_02840	ENOG4105PGM	cation diffusion facilitator family transporter
AO498_02845	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AO498_02850	ENOG4105DY9	regulatoR
AO498_02855	ENOG4108HRK	Histidine kinase
AO498_02880	ENOG4105DTQ	mandelate racemase muconate lactonizing
AO498_02895	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AO498_02915	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AO498_02930	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
AO498_02935	ENOG4108Z9K	Osmotically inducible protein
AO498_02950	ENOG4105JNK	Glycosyl transferase (Group 1
AO498_02960	ENOG4108TJN	glycosyl transferase group 1
AO498_03015	ENOG4105CSM	endonuclease III
AO498_03055	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AO498_03060	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AO498_03070	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AO498_03080	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AO498_03090	ENOG4105C2M	dna polymerase I
AO498_03095	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AO498_03105	ENOG4105K64	Glycosyl transferase, family 2
AO498_03115	ENOG4105DY8	decarboxylase
AO498_03140	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AO498_03155	ENOG4105EWK	phytoene
AO498_03160	ENOG4105EMN	RNA polymerase sigma factor
AO498_03185	ENOG4105KAV	tspo and mbr like protein
AO498_03190	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AO498_03200	ENOG4105F8J	Adenylate Guanylate cyclase
AO498_03205	ENOG4108NEV	two component transcriptional regulator, LytTR family
AO498_03210	ENOG4105BZU	Histidine kinase
AO498_03215	ENOG4105F8J	Adenylate Guanylate cyclase
AO498_03220	ENOG4105BZU	Histidine kinase
AO498_03235	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AO498_03240	ENOG4105K56	Transcriptional regulator
AO498_03245	ENOG4105CK5	oxidoreductase
AO498_03250	ENOG4105C5Q	Transcriptional regulator
AO498_03285	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AO498_03295	ENOG4108JA2	transcriptioN-repair coupling factor
AO498_03300	ENOG4107R3R	Cytochrome o ubiquinol oxidase subunit III
AO498_03320	ENOG4108V0P	LemA family
AO498_03340	ENOG4105CP7	Triose-phosphate isomerase
AO498_03345	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AO498_03355	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AO498_03360	ENOG4108IUZ	ABC transporter
AO498_03380	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AO498_03385	ENOG4108HRK	Histidine kinase
AO498_03390	ENOG4108NEV	two component transcriptional regulator, LytTR family
AO498_03395	ENOG41074H6	response regulator
AO498_03400	ENOG4108IAB	Phoh family
AO498_03410	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AO498_03415	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AO498_03465	ENOG41089UC	methyltransferase, type 11
AO498_03490	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AO498_03515	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AO498_03530	ENOG4105K64	Glycosyl transferase, family 2
AO498_03550	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AO498_03600	ENOG4105D64	Mechanosensitive ion channel
AO498_03620	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AO498_03625	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AO498_03635	ENOG4105CH2	amidohydrolase
AO498_03660	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
AO498_03670	ENOG4105D9R	oxidoreductase
AO498_03680	ENOG4108ZGX	Histidine kinase
AO498_03695	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AO498_03705	ENOG4105DBI	uridine monophosphokinase
AO498_03710	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AO498_03715	ENOG4108URH	decarboxylase
AO498_03770	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AO498_03775	ENOG4105C5H	ABC transporter
AO498_03790	ENOG4105C72	UPF0176 protein
AO498_03810	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
AO498_03825	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AO498_03830	ENOG41083X6	30S ribosomal protein S21
AO498_03840	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AO498_03845	ENOG4105K4H	Nlp p60 protein
AO498_03860	ENOG4105C5Z	peptidase
AO498_03865	ENOG4105CPF	Cell wall formation (By similarity)
AO498_03875	ENOG4108URH	decarboxylase
AO498_03895	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
AO498_03905	ENOG4105C1G	acyl-Coa dehydrogenase
AO498_03920	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AO498_03925	ENOG4107RWD	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AO498_03930	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AO498_03940	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AO498_04030	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AO498_04040	ENOG4105C28	cystathionine
AO498_04055	ENOG4105E6M	Sulphatase-modifying factor protein
AO498_04060	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AO498_04065	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
AO498_04075	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AO498_04085	ENOG4108Z7R	Chaperone CsaA
AO498_04095	ENOG4107QI6	Cysteine desulfurase
AO498_04100	ENOG4107QKV	phosphomannomutase
AO498_04110	ENOG4105DXN	mazG family
AO498_04125	ENOG4105C9Q	fumarate hydratase class II
AO498_04140	ENOG4105CK7	Sodium proline symporter
AO498_04165	ENOG4105CFH	Aspartokinase
AO498_04170	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AO498_04180	ENOG4107R0V	Pyruvate dehydrogenase
AO498_04185	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AO498_04200	ENOG4108YZA	Nitrogen regulatory protein pii
AO498_04215	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AO498_04225	ENOG4105C5R	Aminotransferase
AO498_04230	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AO498_04255	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AO498_04265	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AO498_04270	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AO498_04275	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AO498_04280	ENOG4105K5M	30s ribosomal protein S16
AO498_04350	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AO498_04355	ENOG4105CTU	Proline racemase
AO498_04365	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AO498_04415	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AO498_04430	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AO498_04440	ENOG4105SCY	DNAK suppressor
AO498_04445	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AO498_04460	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AO498_04465	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AO498_04485	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AO498_04495	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AO498_04500	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AO498_04505	ENOG4105CNU	cell division protein FtsK
AO498_04520	ENOG4105KTH	gatB Yqey
AO498_04525	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AO498_04530	ENOG4105EV9	Alpha Beta Hydrolase
AO498_04535	ENOG4105CPN	adenine deaminase
AO498_04545	ENOG4108IGT	Dipeptidase
AO498_04575	ENOG4105ETE	Transcriptional regulator (LacI family
AO498_04580	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
AO498_04585	ENOG4105CPQ	Dehydrogenase
AO498_04605	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AO498_04630	ENOG4108IRC	dna polymerase iii
AO498_04645	ENOG4107QN1	sodium solute
AO498_04665	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AO498_04670	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AO498_04675	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
AO498_04680	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
AO498_04695	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AO498_04700	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AO498_04705	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AO498_04710	ENOG4105E98	transcriptional regulator DeoR family
AO498_04720	ENOG4105DR9	pseudouridine synthase
AO498_04730	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AO498_04735	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
AO498_04745	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AO498_04780	ENOG4107YM1	mraZ protein
AO498_04785	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AO498_04795	ENOG4105CJN	penicillin-binding protein
AO498_04800	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AO498_04805	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AO498_04810	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AO498_04820	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AO498_04825	ENOG4105DFU	Cell wall formation (By similarity)
AO498_04835	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AO498_04840	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AO498_04845	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AO498_04870	ENOG4105CH2	amidohydrolase
AO498_04875	ENOG4105CH2	amidohydrolase
AO498_04900	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AO498_04905	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AO498_04915	ENOG4108IA2	Sodium pantothenate symporter
AO498_04925	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AO498_04930	ENOG4105CHR	reductase
AO498_04955	ENOG4105C27	TonB-dependent Receptor Plug
AO498_04990	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AO498_04995	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AO498_05005	ENOG4105EMN	RNA polymerase sigma factor
AO498_05025	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AO498_05035	ENOG4105C01	Dihydroxy-acid dehydratase
AO498_05040	ENOG4107ZQV	short-chain dehydrogenase reductase
AO498_05050	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AO498_05060	ENOG4105EGD	dinuclear metal center protein, YbgI family
AO498_05095	ENOG4108IUM	Glycogen debranching enzyme
AO498_05105	ENOG4105NTD	Inherit from COG: Hydrolase
AO498_05110	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AO498_05120	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AO498_05125	ENOG4105C0H	protease
AO498_05130	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AO498_05135	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AO498_05150	ENOG4105DA5	(ABC) transporter
AO498_05155	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AO498_05160	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AO498_05170	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
AO498_05180	ENOG4105EFZ	amidohydrolase
AO498_05190	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AO498_05195	ENOG4105C1G	acyl-Coa dehydrogenase
AO498_05200	ENOG4108XG2	Histidine kinase
AO498_05210	ENOG4108RZ2	Glycoside hydrolase family 16
AO498_05215	ENOG4105DZG	Dehydrogenase
AO498_05225	ENOG4105EMU	Dehydrogenase
AO498_05230	ENOG4108UQS	dipeptidase
AO498_05240	ENOG41083MR	nifu domain-containing protein
AO498_05255	ENOG4105FDR	Membrane
AO498_05280	ENOG4105D82	Glutamate dehydrogenase
AO498_05285	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
AO498_05295	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AO498_05300	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AO498_05310	ENOG41074B2	UPF0747 protein
AO498_05315	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AO498_05340	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AO498_05345	ENOG4105C7S	Dehydrogenase
AO498_05350	ENOG4107QN2	dihydrolipoyl dehydrogenase
AO498_05380	ENOG4105EUB	pirin domain protein
AO498_05405	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AO498_05410	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AO498_05415	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AO498_05420	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AO498_05425	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
AO498_05430	ENOG4105CD8	aminopeptidase N
AO498_05470	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AO498_05475	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AO498_05480	ENOG4107VNI	ribosomal protein l10
AO498_05485	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AO498_05490	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AO498_05495	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AO498_05505	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AO498_05510	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AO498_05515	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AO498_05520	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AO498_05525	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AO498_05530	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AO498_05535	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AO498_05540	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AO498_05545	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AO498_05550	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AO498_05555	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AO498_05560	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AO498_05565	ENOG4108628	50s ribosomal protein l29
AO498_05570	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AO498_05575	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AO498_05580	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AO498_05585	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AO498_05590	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AO498_05595	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AO498_05600	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AO498_05605	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AO498_05610	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AO498_05615	ENOG4105VPB	50S ribosomal protein L30
AO498_05620	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AO498_05625	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AO498_05635	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AO498_05640	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AO498_05645	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AO498_05650	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AO498_05655	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AO498_05660	ENOG4108ZT0	50S ribosomal protein l17
AO498_05665	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AO498_05670	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AO498_05685	ENOG4105D7W	serine acetyltransferase
AO498_05690	ENOG4105C6T	cysteine synthase
AO498_05730	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AO498_05740	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AO498_05775	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AO498_05780	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
AO498_05785	ENOG4105CI2	imidazolone-5-propionate hydrolase
AO498_05790	ENOG4105F2Z	3-oxoadipate enol-lactonase
AO498_05810	ENOG4105K56	Transcriptional regulator
AO498_05815	ENOG4108YYC	ycei family
AO498_05820	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
AO498_05830	ENOG4105EYH	Exonuclease
AO498_05837	ENOG4105K6T	rare lipoprotein A
AO498_05885	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
AO498_05890	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
AO498_05910	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AO498_05955	ENOG4105X54	addiction module antidote protein
AO498_05975	ENOG4105CKU	formyltetrahydrofolate synthetase
AO498_05995	ENOG41082J7	Rhodanese domain protein
AO498_06005	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AO498_06010	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AO498_06015	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
AO498_06020	ENOG4105DDC	Oxidoreductase domain protein
AO498_06075	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AO498_06085	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AO498_06090	ENOG4105BZU	Histidine kinase
AO498_06095	ENOG4105BZU	Histidine kinase
AO498_06100	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AO498_06105	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AO498_06130	ENOG4108KF3	Electron transport protein SCO1 SenC
AO498_06145	ENOG4105DJT	lAO AO transport system ATPase
AO498_06150	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AO498_06155	ENOG4105CMN	Methylmalonyl-coA mutase
AO498_06160	ENOG4105D5P	Methylmalonyl-coA mutase
AO498_06180	ENOG4105D4T	Citrate transporter
AO498_06205	ENOG4107Z7P	Ferredoxin
AO498_06210	ENOG4105CAY	ferredoxin--nadp reductase
AO498_06215	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
AO498_06275	ENOG4107U9T	Pfam:Ribonuclease_BN
AO498_06285	ENOG4105HHA	aminodeoxychorismate lyase
AO498_06290	ENOG4105M6F	mutator MutT protein
AO498_06295	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AO498_06320	ENOG4105CY0	Metallo-Beta-Lactamase
AO498_06350	ENOG4105C28	cystathionine
AO498_06360	ENOG4105C98	muts2 protein
AO498_06365	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AO498_06375	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AO498_06380	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AO498_06400	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AO498_06405	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AO498_06410	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AO498_06425	ENOG4107Y2X	deaminase
AO498_06430	ENOG4105DY9	regulatoR
AO498_06435	ENOG4108HRK	Histidine kinase
AO498_06445	ENOG4105CPP	Dehydrogenase, E1 component
AO498_06465	ENOG4105CUT	histidyl-tRNA synthetase
AO498_06475	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AO498_06495	ENOG4105C27	TonB-dependent Receptor Plug
AO498_06520	ENOG4106N3A	copper homeostasis protein cutc
AO498_06530	ENOG41080XP	Cbs domain
AO498_06535	ENOG4105C28	cystathionine
AO498_06540	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AO498_06545	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AO498_06550	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AO498_06580	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AO498_06585	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AO498_06590	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
AO498_06600	ENOG4105FQ6	thiopurine methyltransferase
AO498_06615	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AO498_06620	ENOG4105C3F	Signal peptidase i
AO498_06625	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AO498_06635	ENOG4105FA0	parb-like partition protein
AO498_06640	ENOG4107QJE	Chromosome Partitioning Protein
AO498_06645	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AO498_06650	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AO498_06670	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AO498_06685	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AO498_06695	ENOG4105CAK	Cell division ATP-binding protein ftsE
AO498_06705	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AO498_06760	ENOG4105KME	endoribonuclease L-psp
AO498_06775	ENOG4105EGS	Mechanosensitive ion channel
AO498_06780	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AO498_06785	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AO498_06790	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AO498_06810	ENOG4105EUJ	GTP cyclohydrolase i
AO498_06815	ENOG4105CHR	reductase
AO498_06835	ENOG4107T0X	DNA ligase
AO498_06840	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AO498_06850	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AO498_06855	ENOG4105KUZ	arsenate reductase
AO498_06875	ENOG4105EXW	epimerase dehydratase
AO498_06880	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AO498_06890	ENOG4105EEI	dihydropteroate synthase
AO498_06905	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AO498_06920	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AO498_06930	ENOG4105DI5	UPF0365 protein
AO498_06940	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AO498_06960	ENOG4105C72	UPF0176 protein
AO498_06970	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AO498_06980	ENOG4105CND	Glycosyl transferase, family 2
AO498_06985	ENOG410838F	Glycosyl transferase family 2
AO498_07020	ENOG4105EPC	oxidoreductase
AO498_07040	ENOG4107QUV	Domain protein
AO498_07040	ENOG4107QUV	Domain protein
AO498_07105	ENOG4105E0A	ABC, transporter
AO498_07110	ENOG4105EHG	Permease protein
AO498_07135	ENOG4105C0H	protease
AO498_07140	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AO498_07145	ENOG4105DZP	Membrane-associated zinc metalloprotease
AO498_07160	ENOG4105BZU	Histidine kinase
AO498_07165	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AO498_07170	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AO498_07175	ENOG410904N	short-chain dehydrogenase reductase
AO498_07180	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AO498_07185	ENOG4105VEQ	Cold shock protein
AO498_07190	ENOG4105VN1	Heat shock protein
AO498_07195	ENOG4105C0H	protease
AO498_07200	ENOG4107S1E	Beta-lactamase
AO498_07205	ENOG4105BZU	Histidine kinase
AO498_07210	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
AO498_07215	ENOG4105E08	Glycoside hydrolase, family 9
AO498_07220	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AO498_07235	ENOG4105QJH	Domain of unknown function (DUF718)
AO498_07240	ENOG4107S8A	protein TIM barrel
AO498_07245	ENOG4105CPQ	Dehydrogenase
AO498_07250	ENOG4105CPC	Aldo Keto reductase
AO498_07260	ENOG4105BZU	Histidine kinase
AO498_07280	ENOG4105VZ8	Transcriptional regulator
AO498_07295	ENOG4107RF2	cellulose-binding family II protein
AO498_07305	ENOG4105BZU	Histidine kinase
AO498_07310	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AO498_07315	ENOG4108Z4K	mutator MutT protein
AO498_07330	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AO498_07370	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AO498_07375	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AO498_07390	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AO498_07395	ENOG4105YA8	Transcriptional regulator
AO498_07400	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AO498_07410	ENOG4108JYZ	YitT family
AO498_07460	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AO498_07465	ENOG4105GR3	Histidine kinase
AO498_07510	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AO498_07520	ENOG4105CUB	amino acid
AO498_07525	ENOG4105C6K	Malic enzyme
AO498_07530	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AO498_07585	ENOG41076HS	cation diffusion facilitator family transporter
AO498_07590	ENOG4105D5Q	Arginine ornithine antiporter
AO498_07605	ENOG4105CHM	Aminotransferase
AO498_07610	ENOG4105CQC	Prephenate dehydratase
AO498_07615	ENOG4107S18	3-phosphoshikimate 1-carboxyvinyltransferase
AO498_07620	ENOG4105D49	3-dehydroquinate synthase
AO498_07625	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AO498_07635	ENOG4105CRK	lysyL-tRNA synthetase
AO498_07660	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AO498_07665	ENOG4107QX3	carboxylase
AO498_07695	ENOG4105KRF	dihydroneopterin aldolase
AO498_07715	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AO498_07740	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AO498_07745	ENOG4105CBG	Sulfatase
AO498_07750	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AO498_07755	ENOG4108ZVT	methylmalonyl-coA epimerase
AO498_07765	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AO498_07770	ENOG4108N5B	2-phosphosulfolactate phosphatase
AO498_07785	ENOG4105CPC	Aldo Keto reductase
AO498_07790	ENOG4105CI3	gtp-binding protein typa
AO498_07795	ENOG4105C09	Bile acid
AO498_07845	ENOG4105C26	Dehydrogenase
AO498_07860	ENOG4105D3R	alkyl hydroperoxide reductase
AO498_07875	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AO498_07880	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AO498_07900	ENOG4105C8T	Leucyl-tRNA synthetase
AO498_07915	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AO498_07920	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AO498_07930	ENOG4105C27	TonB-dependent Receptor Plug
AO498_07960	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AO498_07965	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AO498_07970	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AO498_07975	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AO498_07985	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AO498_07990	ENOG41090R7	Ferric uptake
AO498_07995	ENOG4105WN5	stage II sporulation protein
AO498_08000	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AO498_08035	ENOG4105C59	p-type ATPase
AO498_08060	ENOG4105C58	cytochrome c oxidase accessory protein ccog
AO498_08075	ENOG4105D4P	Coproporphyrinogen iii oxidase
AO498_08080	ENOG4105EEF	Alkane 1-monooxygenase
AO498_08085	ENOG4107QVM	von Willebrand factor, type A
AO498_08105	ENOG4105C98	muts2 protein
AO498_08115	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AO498_08120	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AO498_08125	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AO498_08130	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AO498_08135	ENOG4105DCI	Phosphohydrolase
AO498_08145	ENOG4105K8N	protein family UPF0079, ATPase
AO498_08150	ENOG4105DCF	alanine dehydrogenase
AO498_08155	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AO498_08175	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AO498_08180	ENOG4105F0N	pyrophosphate phospho-hydrolase
AO498_08200	ENOG4105C1J	atp-dependent rna helicase
AO498_08215	ENOG4105CHR	reductase
AO498_08220	ENOG4105C6Z	Gluconate
AO498_08240	ENOG4107PU6	Membrane
AO498_08290	ENOG4108W15	Protein of unknown function (DUF1456)
AO498_08325	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AO498_08335	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AO498_08350	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AO498_08355	ENOG4105CN9	Peptidase m42 family protein
AO498_08365	ENOG4105BZU	Histidine kinase
AO498_08380	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AO498_08400	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AO498_08420	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AO498_08425	ENOG4105BZG	amino acid carrier protein
AO498_08465	ENOG4105DYC	esterase
AO498_08470	ENOG4105DYC	esterase
AO498_08500	ENOG4105EBR	Carboxylesterase
AO498_08505	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AO498_08510	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AO498_08550	ENOG4105MA4	psp1 domain protein
AO498_08555	ENOG4105C12	Phosphoribosylglycinamide synthetase
AO498_08560	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AO498_08565	ENOG4105C2X	Arabinose 5-phosphate isomerase
AO498_08575	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AO498_08585	ENOG4108KQJ	Type 11 methyltransferase
AO498_08595	ENOG4105K63	Thioredoxin
AO498_08600	ENOG4107TPS	domain protein
AO498_08630	ENOG4105NQN	cytochrome C
AO498_08645	ENOG4105C1J	atp-dependent rna helicase
AO498_08660	ENOG4105C5I	Dehydrogenase
AO498_08695	ENOG4105BZU	Histidine kinase
AO498_08700	ENOG4105BZU	Histidine kinase
AO498_08705	ENOG4105E0X	reductase
AO498_08725	ENOG4105C3J	Cysteine desulfurase
AO498_08730	ENOG4105BZU	Histidine kinase
AO498_08735	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AO498_08755	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AO498_08760	ENOG4107RBB	ABC transporter, permease
AO498_08770	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AO498_08780	ENOG4107RBB	ABC transporter, permease
AO498_08785	ENOG4107RBB	ABC transporter, permease
AO498_08800	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AO498_08805	ENOG4107RBB	ABC transporter, permease
AO498_08810	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AO498_08825	ENOG4105C7Z	Conserved Protein
AO498_08830	ENOG4105C25	Primosomal protein n'
AO498_08850	ENOG4105CA9	Pyruvate kinase
AO498_08870	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AO498_08875	ENOG4108MR6	WD40-like Beta Propeller Repeat
AO498_08910	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AO498_08915	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AO498_08935	ENOG4108ZAF	Molybdopterin
AO498_08960	ENOG4107ZT5	Thiol disulfide interchange protein
AO498_08965	ENOG4105BZM	domain protein
AO498_08970	ENOG4105C27	TonB-dependent Receptor Plug
AO498_08980	ENOG41067QW	Transcriptional regulator
AO498_09015	ENOG41088SP	formiminoglutamate hydrolase
AO498_09020	ENOG4105CGP	Urocanate hydratase
AO498_09030	ENOG4105C84	Histidine ammonia-lyase
AO498_09035	ENOG4107RSM	transcriptional regulator
AO498_09040	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AO498_09045	ENOG4105E4F	Isochorismate synthase
AO498_09050	ENOG4105KA0	thioesterase Superfamily protein
AO498_09055	ENOG4107TB6	phosphoglycerate mutase
AO498_09070	ENOG4105EGD	dinuclear metal center protein, YbgI family
AO498_09075	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AO498_09090	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AO498_09110	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AO498_09125	ENOG41061MV	Arylsulfatase
AO498_09135	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AO498_09140	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AO498_09150	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AO498_09155	ENOG4105D3Q	Sugar transferase
AO498_09170	ENOG4105CI2	imidazolone-5-propionate hydrolase
AO498_09185	ENOG4105BZU	Histidine kinase
AO498_09190	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AO498_09195	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AO498_09225	ENOG4108JU7	Transcriptional regulator
AO498_09230	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AO498_09245	ENOG4108Z0R	Transferase
AO498_09265	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
AO498_09280	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AO498_09285	ENOG4108Z4K	mutator MutT protein
AO498_09290	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AO498_09310	ENOG4105C7H	Helicase, RecD TraA family
AO498_09320	ENOG4105BZ1	(ABC) transporter
AO498_09330	ENOG4107WP9	Histidine kinase
AO498_09335	ENOG4105DY9	regulatoR
AO498_09345	ENOG4108UZ3	Transporter
AO498_09350	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AO498_09370	ENOG4108S4H	thioesterase Superfamily protein
AO498_09375	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AO498_09380	ENOG4108R6K	riboflavin synthase, subunit alpha
AO498_09405	ENOG4108SU4	UPF0309 protein
AO498_09425	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AO498_09430	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AO498_09435	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AO498_09440	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AO498_09442	ENOG4105WXV	50S ribosomal protein L32
AO498_09450	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AO498_09455	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AO498_09460	ENOG4105CJW	magnesium transporter
AO498_09465	ENOG4108JQ1	Dehydrogenase
AO498_09470	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AO498_09495	ENOG4107QSV	RmuC domain protein
AO498_09500	ENOG4105C1A	potassium transporter peripheral membrane
AO498_09505	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AO498_09510	ENOG4107QRT	dEAD DEAH box helicase
AO498_09515	ENOG4107T0X	DNA ligase
AO498_09540	ENOG4105DR4	Methyltransferase
AO498_09545	ENOG4105CK7	Sodium proline symporter
AO498_09550	ENOG4105C5H	ABC transporter
AO498_09565	ENOG4105CMR	udp-glucose 4-epimerase
AO498_09570	ENOG4105KST	dependent repressor
AO498_09575	ENOG4105D05	Receptor
AO498_09600	ENOG4105CMG	Carbohydrate kinase
AO498_09605	ENOG4105C93	Xylose Isomerase
AO498_09640	ENOG4105C1G	acyl-Coa dehydrogenase
AO498_09645	ENOG4105CEY	Amp-dependent synthetase and ligase
AO498_09660	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AO498_09675	ENOG4105CY3	ABC transporter, permease
AO498_09680	ENOG4105DHJ	ABC, transporter
AO498_09690	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AO498_09695	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AO498_09700	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AO498_09740	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AO498_09780	ENOG4107RE3	peptidase, S41
AO498_09790	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AO498_09800	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AO498_09830	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
AO498_09845	ENOG4108MUZ	hydrolase
AO498_09860	ENOG4105DFA	alanine racemase domain protein
AO498_09875	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AO498_09880	ENOG4105DCF	alanine dehydrogenase
AO498_09885	ENOG4105CPP	Dehydrogenase, E1 component
AO498_09900	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AO498_09925	ENOG4107YZX	Universal stress protein
AO498_09930	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
AO498_09940	ENOG4105C75	arginyL-tRNA synthetase
AO498_09945	ENOG4105CYW	agmatinase
AO498_09970	ENOG4105CSU	acyl-Coa dehydrogenase
AO498_09975	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
AO498_09980	ENOG4105DMW	Dehydrogenase reductase
AO498_09985	ENOG4105D2H	Uronic isomerase
AO498_09990	ENOG4107KJX	Transcriptional regulator
AO498_09995	ENOG4105TT1	Ragb susd domain-containing protein
AO498_10000	ENOG4105C27	TonB-dependent Receptor Plug
AO498_10005	ENOG4105EPC	oxidoreductase
AO498_10015	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AO498_10050	ENOG4105CD3	dihydroorotase
AO498_10060	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AO498_10070	ENOG4107QJZ	Glycosyl transferase, family 2
AO498_10085	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
AO498_10095	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AO498_10120	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
AO498_10125	ENOG4105EX9	Membrane
AO498_10140	ENOG4107QWK	SAICAR synthetase
AO498_10150	ENOG4105CJ2	(LipO)protein
AO498_10175	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AO498_10185	ENOG4105CHU	acetyl-coa acetyltransferase
AO498_10205	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AO498_10235	ENOG4105II7	pyrroline-5-carboxylate reductase
AO498_10265	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AO498_10270	ENOG4108JQ1	Dehydrogenase
AO498_10300	ENOG4105BZ1	(ABC) transporter
AO498_10315	ENOG4107QZW	Altronate oxidoreductase
AO498_10330	ENOG4105CTX	dehydratase
AO498_10335	ENOG4105EDK	PfkB domain protein
AO498_10345	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AO498_10350	ENOG41069H7	transport system small permease component
AO498_10355	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AO498_10360	ENOG4105D3R	alkyl hydroperoxide reductase
AO498_10390	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AO498_10415	ENOG4105C31	Tryptophanyl-tRNA synthetase
AO498_10480	ENOG4105DJV	ribulose-phosphate 3-epimerase
AO498_10495	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AO498_10525	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
AO498_10565	ENOG4109015	Biopolymer transport protein exbD tolR
AO498_10580	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AO498_10585	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AO498_10600	ENOG4105CHR	reductase
AO498_10605	ENOG4105CPQ	Dehydrogenase
AO498_10615	ENOG4105CPN	adenine deaminase
AO498_10620	ENOG41067SE	Tetr family transcriptional regulator
AO498_10625	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AO498_10640	ENOG4107ZYR	domain protein
AO498_10645	ENOG4105CZN	Potassium uptake protein
AO498_10670	ENOG4105DGU	Histone deacetylase
AO498_10695	ENOG4105E2D	ec 3.2.1.52
AO498_10700	ENOG4105BZG	amino acid carrier protein
AO498_10705	ENOG4105BZW	Glycerate kinase
AO498_10725	ENOG4108NEV	two component transcriptional regulator, LytTR family
AO498_10745	ENOG4107R0I	Cell wall formation (By similarity)
AO498_10765	ENOG4105CNT	hydrolase family 2
AO498_10775	ENOG4105C59	p-type ATPase
AO498_10780	ENOG4108MGY	Histidine kinase
AO498_10785	ENOG4105DHQ	Histidine kinase
AO498_10810	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AO498_10815	ENOG4105WH1	Two component transcriptional regulator luxr family
AO498_10865	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AO498_10875	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AO498_10945	ENOG4105CQ7	ATP-dependent helicase
AO498_10955	ENOG4105DFU	Cell wall formation (By similarity)
AO498_10965	ENOG4105CDU	Replicative dna helicase
AO498_10970	ENOG4105CB2	alcohol dehydrogenase
AO498_10985	ENOG4105BZJ	Electron transfer flavoprotein
AO498_10990	ENOG4105C10	Electron transfer flavoprotein
AO498_11000	ENOG4105D9N	nucleoside
AO498_11010	ENOG4105DR9	pseudouridine synthase
AO498_11015	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AO498_11020	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AO498_11060	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AO498_11080	ENOG4105D7N	magnesium and cobalt transport protein CorA
AO498_11090	ENOG4105VCH	membrane
AO498_11100	ENOG4105C1G	acyl-Coa dehydrogenase
AO498_11115	ENOG4105DWV	Homoserine O-trans-acetylase
AO498_11125	ENOG4105CHH	sulfate transporter
AO498_11130	ENOG4105CH7	arginosuccinase
AO498_11140	ENOG4107T6X	nag kinase
AO498_11145	ENOG4107REN	Carbamoyltransferase
AO498_11150	ENOG4105C8Y	Acetylornithine aminotransferase
AO498_11155	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AO498_11160	ENOG4105CDH	Citrulline--aspartate ligase
AO498_11170	ENOG4105C9B	Cysteine desulfurase
AO498_11180	ENOG4107ZXU	DSBA oxidoreductase
AO498_11195	ENOG4105P4J	Allophanate hydrolase, subunit 1
AO498_11200	ENOG4105E7W	lamb ycsf family protein
AO498_11220	ENOG4105CHM	Aminotransferase
AO498_11240	ENOG4108HRK	Histidine kinase
AO498_11245	ENOG4105DY9	regulatoR
AO498_11250	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AO498_11275	ENOG4105ZMH	deoxynucleoside kinase
AO498_11280	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AO498_11285	ENOG4105QNR	S1 RNA binding domain protein
AO498_11315	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
AO498_11320	ENOG4105DF5	DNA topoisomerase IV, subunit A
AO498_11325	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
AO498_11335	ENOG4108ZCU	PPIases accelerate the folding of proteins
AO498_11340	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
AO498_11345	ENOG4105DUX	Transporter
AO498_11350	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AO498_11360	ENOG4107QNJ	CoA-transferase subunit B
AO498_11365	ENOG4105D6N	CoA-transferase, subunit a
AO498_11370	ENOG4105DTN	riboflavin biosynthesis protein ribF
AO498_11375	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AO498_11385	ENOG4107RJ9	Cell division protein FtsX
AO498_11410	ENOG4105C1J	atp-dependent rna helicase
AO498_11425	ENOG4105D5Q	Arginine ornithine antiporter
AO498_11445	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AO498_11450	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AO498_11460	ENOG4108Z03	MAF-like protein
AO498_11470	ENOG4105K4I	Scp-like extracellular
AO498_11475	ENOG4105CUY	Mechanosensitive ion channel
AO498_11490	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AO498_11505	ENOG4108HKT	sucrose-6-phosphate hydrolase
AO498_11510	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
AO498_11530	ENOG4105CEY	Amp-dependent synthetase and ligase
AO498_11570	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AO498_11590	ENOG4105DZR	Type I site-specific deoxyribonuclease
AO498_11600	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
AO498_11610	ENOG4105CVR	type I restriction-modification system
AO498_11655	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AO498_11665	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AO498_11675	ENOG4105CC5	ABC transporter
AO498_11680	ENOG4105CC5	ABC transporter
AO498_11685	ENOG4105DIK	(ABC) transporter
AO498_11690	ENOG4105DSE	periplasmic solute binding protein
AO498_11705	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
AO498_11725	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
AO498_11755	ENOG4105CE4	GlcNAc 6-P deacetylase
AO498_11760	ENOG4105D9R	oxidoreductase
AO498_11785	ENOG4105C9K	Endothelin-converting enzyme 1
AO498_11805	ENOG4105C8P	)-transporter
AO498_11810	ENOG4108HRK	Histidine kinase
AO498_11815	ENOG4105DY9	regulatoR
AO498_11820	ENOG4105FTV	AraC Family Transcriptional Regulator
AO498_11825	ENOG4105UTB	Blue (Type 1) copper domain protein
AO498_11830	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
AO498_11875	ENOG4108UJU	UPF0301 protein
AO498_11880	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AO498_11890	ENOG4105E4C	Lytic transglycosylase catalytic
AO498_11895	ENOG4105C3M	thioredoxin reductase
AO498_11900	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AO498_11905	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AO498_11910	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AO498_11930	ENOG4105VC4	domain protein
AO498_11940	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AO498_11945	ENOG4105VJV	50s ribosomal protein L35
AO498_11950	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AO498_11955	ENOG4105C22	threonyL-tRNA synthetase
AO498_11965	ENOG4105D5U	fad dependent oxidoreductase
AO498_11980	ENOG4105CBX	hi0933 family
AO498_11985	ENOG4105D7A	ATP-binding protein
AO498_11990	ENOG4105C3J	Cysteine desulfurase
AO498_11995	ENOG4105KVH	Transcriptional regulator
AO498_12000	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AO498_12005	ENOG4105DTD	Dehydrogenase
AO498_12055	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AO498_12070	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
AO498_12085	ENOG41090A1	ferritin
AO498_12095	ENOG4105E6M	Sulphatase-modifying factor protein
AO498_12110	ENOG4105D78	K07001 NTE family protein
AO498_12115	ENOG4105C8F	Beta-lactamase domain protein
AO498_12120	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AO498_12135	ENOG4106HBN	Galactosamine-6-phosphate isomerase
AO498_12140	ENOG4105C1J	atp-dependent rna helicase
AO498_12155	ENOG4105C79	DNA protecting protein DprA
AO498_12175	ENOG4105SYT	Methylenetetrahydrofolate reductase
AO498_12180	ENOG4105C3R	Methionine synthase
AO498_12185	ENOG4105C3R	Methionine synthase
AO498_12195	ENOG4105BZU	Histidine kinase
AO498_12200	ENOG4105K8R	UPF0145 protein
AO498_12215	ENOG4105P8F	nudix hydrolase
AO498_12225	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
AO498_12235	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AO498_12260	ENOG4105F7J	membrane-bound serine protease
AO498_12275	ENOG410853W	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AO498_12285	ENOG4105C19	ABC transporter
AO498_12290	ENOG4108WBT	adenosyltransferase
AO498_12295	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AO498_12305	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AO498_12310	ENOG4105CZM	Major Facilitator
AO498_12320	ENOG4107QI1	Mate efflux family protein
AO498_12330	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
AO498_12345	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AO498_12355	ENOG4105K8Z	Phage shock protein
AO498_12370	ENOG4108VCT	Sulfite exporter TauE/SafE
AO498_12405	ENOG4105CE1	Ferrous iron transport protein b
AO498_12425	ENOG4105EMN	RNA polymerase sigma factor
AO498_12445	ENOG4105CUG	Oligopeptidase b
AO498_12450	ENOG4108Z5K	methylglyoxal synthase
AO498_12455	ENOG4105CTQ	phosphohexokinase
AO498_12460	ENOG4105CG3	alpha amylase, catalytic region
AO498_12465	ENOG4105D2N	Aldolase
AO498_12470	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AO498_12480	ENOG4105ETE	Transcriptional regulator (LacI family
AO498_12500	ENOG4108JA5	May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity)
AO498_12505	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AO498_12515	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AO498_12520	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AO498_12530	ENOG41083MR	nifu domain-containing protein
AO498_12540	ENOG4105D9P	serine threonine protein kinase
AO498_12550	ENOG41082J7	Rhodanese domain protein
AO498_12575	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
AO498_12605	ENOG4105CHH	sulfate transporter
AO498_12610	ENOG4105D65	subunit l
AO498_12615	ENOG4105EVH	UPF0753 protein
AO498_12625	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
AO498_12635	ENOG4108RWI	nicotinamidase
AO498_12640	ENOG4105DAP	Nicotinate phosphoribosyltransferase
AO498_12690	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AO498_12695	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AO498_12700	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AO498_12715	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AO498_12720	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AO498_12760	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AO498_12765	ENOG4105C8Y	Acetylornithine aminotransferase
AO498_12790	ENOG4105E0X	reductase
AO498_12800	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AO498_12805	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AO498_12810	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AO498_12815	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AO498_12830	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AO498_12835	ENOG4107R34	abc transporter permease protein
AO498_12840	ENOG4105EHZ	conserved protein UCP016719
AO498_12845	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AO498_12855	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
AO498_12860	ENOG4108IXY	short-chain dehydrogenase reductase
AO498_12865	ENOG4105CEV	competence damage-inducible protein
AO498_12875	ENOG4105BZU	Histidine kinase
AO498_12895	ENOG4105D5P	Methylmalonyl-coA mutase
AO498_12920	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AO498_12925	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AO498_12930	ENOG4105H3G	oxidoreductase
AO498_12945	ENOG4105CPC	Aldo Keto reductase
AO498_12960	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AO498_12970	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AO498_12975	ENOG4105DZ0	fad dependent oxidoreductase
AO498_12985	ENOG4105C02	permease
AO498_12990	ENOG4105DYC	esterase
AO498_13000	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AO498_13005	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AO498_13015	ENOG4105BZU	Histidine kinase
AO498_13030	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AO498_13045	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AO498_13050	ENOG4105EDR	glucose galactose transporter
AO498_13080	ENOG4105D9R	oxidoreductase
AO498_13110	ENOG4105QE3	oxidoreductase
AO498_13115	ENOG4105BZU	Histidine kinase
AO498_13125	ENOG4105CPC	Aldo Keto reductase
AO498_13130	ENOG4105CTQ	phosphohexokinase
AO498_13140	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AO498_13145	ENOG4105BZU	Histidine kinase
AO498_13150	ENOG4108MGY	Histidine kinase
AO498_13160	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AO498_13175	ENOG4105DY9	regulatoR
AO498_13180	ENOG4108HRK	Histidine kinase
AO498_13190	ENOG4105CA9	Pyruvate kinase
AO498_13200	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AO498_13205	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AO498_13210	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AO498_13220	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AO498_13225	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AO498_13250	ENOG4105DGW	oligopeptidase A
AO498_13255	ENOG4105C02	permease
AO498_13265	ENOG4105BZU	Histidine kinase
AO498_13280	ENOG4108I0Z	Aconitate hydratase
AO498_13285	ENOG4105CRW	Short chain fatty acid transporter
AO498_13300	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AO498_13310	ENOG4105C02	permease
AO498_13315	ENOG4105C3G	gtp-binding protein
AO498_13330	ENOG4105C5H	ABC transporter
AO498_13335	ENOG4105DKB	L-sorbosone dehydrogenase
AO498_13350	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AO498_13360	ENOG4105DNZ	Alpha Beta Hydrolase
AO498_13365	ENOG4108RAV	Conserved protein
AO498_13370	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AO498_13390	ENOG4105E2R	ROK family
AO498_13405	ENOG41061MV	Arylsulfatase
AO498_13430	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AO498_13435	ENOG4105C5Z	peptidase
AO498_13445	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AO498_13450	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AO498_13455	ENOG4105BZU	Histidine kinase
AO498_13510	ENOG4105VRT	cytoplasmic protein
AO498_13515	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AO498_13520	ENOG4105CKK	Glycosyl transferase, family 2
AO498_13530	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AO498_13535	ENOG4108F2G	Chain length determinant protein
AO498_13585	ENOG4105CPK	Glycosyl transferase (Group 1
AO498_13595	ENOG4108DRC	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AO498_13625	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AO498_13630	ENOG41090R9	glycosyltransferase
AO498_13640	ENOG4107R0E	Glycosyl transferase, family 2
AO498_13645	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AO498_13695	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
AO498_13705	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
AO498_13715	ENOG4105K64	Glycosyl transferase, family 2
AO498_13730	ENOG4105K64	Glycosyl transferase, family 2
AO498_13735	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AO498_13745	ENOG4105CKK	Glycosyl transferase, family 2
AO498_13770	ENOG4105ESV	Glycosyl transferase, family 4
AO498_13780	ENOG4107YJ4	chain length determinant protein
AO498_13790	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
AO498_13795	ENOG41082IR	Excinuclease ABC C subunit domain protein
AO498_13810	ENOG4107T8Q	Glycosyl transferase (Group 1
AO498_13835	ENOG4105F0R	Cytidylyltransferase
AO498_13845	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
AO498_13850	ENOG4105D2T	synthase
AO498_13860	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AO498_13870	ENOG4107QQG	Dehydrogenase
AO498_13875	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AO498_13885	ENOG4105C30	Nad-dependent epimerase dehydratase
AO498_13890	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AO498_13895	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AO498_13900	ENOG4108TJN	glycosyl transferase group 1
AO498_13905	ENOG4105X1N	Glycosyl transferase family 8
AO498_13940	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AO498_13960	ENOG4105C27	TonB-dependent Receptor Plug
AO498_13970	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
AO498_13975	ENOG4105D2T	synthase
AO498_13980	ENOG4105F0R	Cytidylyltransferase
AO498_14005	ENOG4105CAQ	asparagine synthetase
AO498_14050	ENOG4105CPK	Glycosyl transferase (Group 1
AO498_14060	ENOG4105CAQ	asparagine synthetase
AO498_14070	ENOG4105BZ1	(ABC) transporter
AO498_14090	ENOG4107QQG	Dehydrogenase
AO498_14100	ENOG4105JEU	Glycosyl transferase, family 2
AO498_14150	ENOG4105PSV	Polysaccharide Biosynthesis Protein
AO498_14160	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AO498_14180	ENOG4105CUJ	penicillin amidase
AO498_14180	ENOG4105CUJ	penicillin amidase
AO498_14200	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AO498_14220	ENOG4108VVK	transcriptional Regulator, AsnC
AO498_14230	ENOG4105C3K	feS assembly ATPase SufC
AO498_14240	ENOG4105C9B	Cysteine desulfurase
AO498_14250	ENOG4105VG1	fes assembly suf system protein
AO498_14255	ENOG4108Y6J	UPF0403 protein
AO498_14270	ENOG4105DHU	Bile acid
AO498_14275	ENOG4108RWN	rrna methyltransferase
AO498_14285	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AO498_14305	ENOG4107QNK	)-transporter
AO498_14310	ENOG4105BZU	Histidine kinase
AO498_14315	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AO498_14320	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
AO498_14330	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AO498_14335	ENOG4105DY9	regulatoR
AO498_14345	ENOG4107QP8	phosphohexose isomerase
AO498_14355	ENOG4105DHJ	ABC, transporter
AO498_14360	ENOG4105CY3	ABC transporter, permease
AO498_14365	ENOG4105BZU	Histidine kinase
AO498_14385	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AO498_14390	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
AO498_14395	ENOG4105CQB	FAD linked oxidase domain protein
AO498_14400	ENOG41080C8	DUF218 domain
AO498_14420	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
AO498_14425	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AO498_14435	ENOG4105DKW	ABC transporter
AO498_14440	ENOG4105C9B	Cysteine desulfurase
AO498_14450	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
AO498_14465	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AO498_14470	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AO498_14475	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AO498_14480	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AO498_14485	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AO498_14490	ENOG4105MIR	Phenylalanine 4-monooxygenase
AO498_14495	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
AO498_14500	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AO498_14505	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AO498_14510	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AO498_14515	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AO498_14520	ENOG4107RI6	Anthranilate phosphoribosyltransferase
AO498_14525	ENOG4105DDQ	anthranilate synthase
AO498_14545	ENOG4105C0B	DNA polymerase III (alpha subunit)
AO498_14570	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
AO498_14600	ENOG4105JHY	Membrane
AO498_14620	ENOG4105E39	Enoyl-CoA hydratase
AO498_14650	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AO498_14655	ENOG4105E9H	Lytic Murein transglycosylase
AO498_14665	ENOG4105C6K	Malic enzyme
AO498_14670	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AO498_14680	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AO498_14700	ENOG4105DSJ	YicC domain protein
AO498_14710	ENOG41080HI	glycine oxidase
AO498_14715	ENOG4105C5X	domain protein
AO498_14720	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AO498_14740	ENOG4105K64	Glycosyl transferase, family 2
AO498_14765	ENOG4105DFD	Na H antiporter
AO498_14770	ENOG4105CT3	Monooxygenase
AO498_14800	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
AO498_14810	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AO498_14815	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AO498_14825	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AO498_14830	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AO498_14840	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AO498_14845	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AO498_14850	ENOG4105BZU	Histidine kinase
AO498_14875	ENOG4105E6M	Sulphatase-modifying factor protein
AO498_14880	ENOG4105C5Z	peptidase
AO498_14915	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AO498_14925	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AO498_14930	ENOG4105W8H	transhydrogenase (subunit alpha
AO498_14935	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AO498_14945	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AO498_14980	ENOG4107TYG	Oxidoreductase domain-containing protein
AO498_14985	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AO498_14990	ENOG4105NAE	bifunctional deaminase-reductase domain protein
AO498_15020	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AO498_15025	ENOG4105C8N	cysteinyl-tRNA synthetase
AO498_15030	ENOG4107VAM	peptidase, m28
AO498_15035	ENOG4105ETE	Transcriptional regulator (LacI family
AO498_15040	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AO498_15080	ENOG4105W2Z	cytochrome C, class I
AO498_15105	ENOG41061MV	Arylsulfatase
AO498_15115	ENOG4105C9F	isomerase
AO498_15135	ENOG4105FDP	GntR family transcriptional regulator
AO498_15145	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AO498_15150	ENOG4107QR9	Iron-sulfur cluster binding protein
AO498_15155	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
AO498_15160	ENOG4105C08	Histidine kinase
AO498_15165	ENOG4108JA5	May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity)
AO498_15200	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AO498_15215	ENOG4105ES5	Histidine kinase
AO498_15225	ENOG4108SJC	Membrane
AO498_15245	ENOG4105CCU	oxidase (Subunit III)
AO498_15250	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AO498_15260	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AO498_15265	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AO498_15290	ENOG4107SFQ	iron-sulfur binding
AO498_15315	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AO498_15325	ENOG4105E9Q	Acyl-transferase
AO498_15345	ENOG4105CJ1	ABC, transporter
AO498_15355	ENOG4105CXT	aspartate transcarbamylase
AO498_15360	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AO498_15375	ENOG4105DCG	PHP domain protein
AO498_15425	ENOG4107QTF	adenylosuccinate lyase
AO498_15455	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AO498_15465	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
AO498_15475	ENOG4105BZU	Histidine kinase
AO498_15485	ENOG4105T58	Dithiol-disulfide isomerase
AO498_15490	ENOG4105CHM	Aminotransferase
AO498_15515	ENOG4108SVW	integral membrane protein
AO498_15540	ENOG4105CAY	ferredoxin--nadp reductase
AO498_15565	ENOG4105CRE	cytochrome C
AO498_15630	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AO498_15640	ENOG4105CBG	Sulfatase
AO498_15645	ENOG4105CBG	Sulfatase
AO498_15650	ENOG4105CBG	Sulfatase
AO498_15660	ENOG4105D05	Receptor
AO498_15705	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AO498_15710	ENOG4107RJ1	sodium solute
AO498_15720	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AO498_15735	ENOG4105KHC	sulfurtransferase
AO498_15740	ENOG4108UT2	hemolysin iii
AO498_15750	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
AO498_15790	ENOG4105C27	TonB-dependent Receptor Plug
AO498_15820	ENOG4105VMP	Transcriptional regulator
AO498_15845	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AO498_15855	ENOG4105CD3	dihydroorotase
AO498_15865	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
AO498_15875	ENOG4108RVA	ribokinase
AO498_15895	ENOG4107S1E	Beta-lactamase
AO498_15900	ENOG4105C1Q	protoporphyrinogen oxidase
AO498_15915	ENOG4105CKW	Inner membrane protein yedI
AO498_15925	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AO498_15930	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
AO498_15945	ENOG4105D1Q	UPF0246 protein
AO498_15995	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AO498_16000	ENOG4105C5S	asparaginyl-tRNA synthetase
AO498_16010	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AO498_16015	ENOG4105DEU	major facilitator superfamily
AO498_16045	ENOG4105HDK	L-asparaginase
AO498_16050	ENOG4105F8V	Hydrolase, tatD family
AO498_16055	ENOG4107R8N	Glycosyl transferase, family 2
AO498_16060	ENOG4108ZJ4	polysaccharide deacetylase
AO498_16080	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AO498_16105	ENOG4106M28	alanine racemase domain protein
AO498_16120	ENOG4105E33	succinate dehydrogenase
AO498_16140	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
AO498_16150	ENOG4105DUM	transcriptional regulator, lysR family
AO498_16155	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AO498_16160	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AO498_16170	ENOG4107XWI	flavin reductase domain protein, FMN-binding
AO498_16185	ENOG4106F60	Histidine kinase
AO498_16190	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AO498_16205	ENOG4105BZA	Phosphoglycerate kinase
AO498_16235	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AO498_16245	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
AO498_16280	ENOG4107RUZ	Sss sodium solute transporter superfamily
AO498_16295	ENOG4108I0Y	(ABC) transporter
AO498_16300	ENOG4108UJV	acyl-CoA thioesterase i
AO498_16345	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AO498_16350	ENOG4105C8J	)-transporter
AO498_16365	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AO498_16370	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AO498_16380	ENOG4107QRG	dna polymerase iii
AO498_16390	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AO498_16405	ENOG4105PAD	Hydrolase
AO498_16410	ENOG4105C26	Dehydrogenase
AO498_16415	ENOG4105CHR	reductase
AO498_16420	ENOG4107QN2	dihydrolipoyl dehydrogenase
AO498_16425	ENOG4105K6V	RNA polymerase
AO498_16445	ENOG4105D1H	recombination factor protein RarA
AO498_16470	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AO498_16490	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AO498_16495	ENOG4105BZ1	(ABC) transporter
AO498_16515	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AO498_16520	ENOG4105QVC	MOSC domain-containing protein
AO498_16530	ENOG4105CFG	Acts as a chaperone (By similarity)
AO498_16535	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AO498_16555	ENOG4105D52	delta-aminolevulinic acid dehydratase
AO498_16565	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
AO498_16570	ENOG4105C8Y	Acetylornithine aminotransferase
AO498_16575	ENOG4105KDC	50s ribosomal protein l28
AO498_16580	ENOG41083ND	50S ribosomal protein L33
AO498_16585	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AO498_16615	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AO498_16620	ENOG4105K64	Glycosyl transferase, family 2
AO498_16640	ENOG4105CD3	dihydroorotase
AO498_16675	ENOG41072GX	Peptidase M22 Glycoprotease
AO498_16680	ENOG4105CN1	protease
AO498_16685	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AO498_16687	ENOG4105VG0	50S ribosomal protein l34
AO498_16745	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AO498_16750	ENOG4105CPP	Dehydrogenase, E1 component
AO498_16760	ENOG41061MV	Arylsulfatase
AO498_16765	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AO498_16795	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AO498_16800	ENOG4107SDT	Homocitrate synthase
AO498_16805	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AO498_16810	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AO498_16815	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AO498_16820	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AO498_16830	ENOG4105C7K	acetolactate synthase
AO498_16835	ENOG4105C01	Dihydroxy-acid dehydratase
AO498_16840	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AO498_16855	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AO498_16860	ENOG4107SJB	teichoic acid biosynthesis
AO498_16865	ENOG4105EMN	RNA polymerase sigma factor
AO498_16870	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AO498_16885	ENOG4105C0B	DNA polymerase III (alpha subunit)
AO498_16895	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
AO498_16900	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)