locus-tag	class	description
GYM62_00030	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GYM62_00045	COG0006	proline dipeptidase activity
GYM62_00065	COG1011	Hydrolase
GYM62_00070	COG1012	belongs to the aldehyde dehydrogenase family
GYM62_00100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GYM62_00120	COG0584	glycerophosphoryl diester phosphodiesterase
GYM62_00130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GYM62_00135	COG0612	Peptidase, M16
GYM62_00140	COG0612	Peptidase, M16
GYM62_00150	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GYM62_00155	COG0594	ribonuclease P activity
GYM62_00165	COG1214	PFAM Peptidase M22, glycoprotease
GYM62_00215	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GYM62_00245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GYM62_00270	COG0563	adenylate kinase activity
GYM62_00275	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GYM62_00280	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GYM62_00285	COG0484	heat shock protein binding
GYM62_00295	COG4152	abc transporter atp-binding protein
GYM62_00300	COG1668	transmembrane transport
GYM62_00305	COG0783	Belongs to the Dps family
GYM62_00310	COG3852	Histidine kinase
GYM62_00315	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GYM62_00370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GYM62_00375	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GYM62_00380	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GYM62_00385	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GYM62_00390	COG1805	sodium ion transport
GYM62_00395	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GYM62_00400	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GYM62_00405	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GYM62_00465	COG0823	Involved in the tonB-independent uptake of proteins
GYM62_00475	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GYM62_00480	COG3118	belongs to the thioredoxin family
GYM62_00490	COG0357	Ribosomal RNA small subunit methyltransferase G
GYM62_00495	COG1595	DNA-templated transcription, initiation
GYM62_00500	COG1215	transferase activity, transferring glycosyl groups
GYM62_00505	COG0343	queuine tRNA-ribosyltransferase activity
GYM62_00530	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GYM62_00535	COG0129	dihydroxy-acid dehydratase activity
GYM62_00540	COG0028	Belongs to the TPP enzyme family
GYM62_00550	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GYM62_00555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GYM62_00560	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GYM62_00565	COG0066	3-isopropylmalate dehydratase activity
GYM62_00610	COG0642	Histidine kinase
GYM62_00630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GYM62_00645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GYM62_00655	COG0584	glycerophosphoryl diester phosphodiesterase
GYM62_00665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GYM62_00685	COG1131	(ABC) transporter
GYM62_00725	COG0658	competence protein
GYM62_00725	COG2333	competence protein COMEC
GYM62_00735	COG0514	ATP-dependent DNA helicase (RecQ)
GYM62_00760	COG0009	L-threonylcarbamoyladenylate synthase
GYM62_00765	COG0126	phosphoglycerate kinase activity
GYM62_00775	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GYM62_00780	COG0052	Belongs to the universal ribosomal protein uS2 family
GYM62_00785	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GYM62_00795	COG0564	pseudouridine synthase activity
GYM62_00805	COG5002	protein histidine kinase activity
GYM62_00810	COG0745	RESPONSE REGULATOR receiver
GYM62_00820	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GYM62_00825	COG0577	efflux transmembrane transporter activity
GYM62_00825	COG1136	(ABC) transporter
GYM62_00830	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GYM62_00840	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GYM62_00850	COG3275	phosphorelay sensor kinase activity
GYM62_00855	COG3279	Response regulator of the LytR AlgR family
GYM62_00870	COG0488	(ABC) transporter
GYM62_00890	COG1408	metallophosphoesterase
GYM62_00900	COG0436	Aminotransferase
GYM62_00915	COG0268	Binds directly to 16S ribosomal RNA
GYM62_00920	COG2003	Belongs to the UPF0758 family
GYM62_00955	COG1418	mRNA catabolic process
GYM62_00965	COG0246	Mannitol dehydrogenase
GYM62_00970	COG2721	sulfolactate sulfo-lyase activity
GYM62_00980	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GYM62_01005	COG2205	protein histidine kinase activity
GYM62_01010	COG1556	Lactate utilization protein
GYM62_01015	COG1139	Iron-sulfur cluster binding protein
GYM62_01020	COG0247	lactate metabolic process
GYM62_01035	COG3119	arylsulfatase activity
GYM62_01040	COG4251	negative regulation of phosphorylation
GYM62_01070	COG2353	YceI-like domain
GYM62_01075	COG4654	Cytochrome c, class I
GYM62_01095	COG1064	alcohol dehydrogenase
GYM62_01140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GYM62_01145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GYM62_01145	COG0512	Glutamine amidotransferase of anthranilate synthase
GYM62_01150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GYM62_01155	COG0134	indole-3-glycerol-phosphate synthase activity
GYM62_01160	COG0135	phosphoribosylanthranilate isomerase activity
GYM62_01165	COG0133	tryptophan synthase activity
GYM62_01170	COG0159	tryptophan synthase activity
GYM62_01175	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GYM62_01180	COG3186	Phenylalanine-4-hydroxylase
GYM62_01190	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GYM62_01195	COG0107	imidazoleglycerol-phosphate synthase activity
GYM62_01200	COG0140	phosphoribosyl-ATP diphosphatase activity
GYM62_01200	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GYM62_01205	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GYM62_01210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GYM62_01215	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GYM62_01220	COG0673	inositol 2-dehydrogenase activity
GYM62_01240	COG4251	negative regulation of phosphorylation
GYM62_01260	COG3177	Filamentation induced by cAMP protein fic
GYM62_01280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GYM62_01290	COG0071	Belongs to the small heat shock protein (HSP20) family
GYM62_01295	COG0071	Belongs to the small heat shock protein (HSP20) family
GYM62_01300	COG3344	reverse transcriptase
GYM62_01320	COG3344	reverse transcriptase
GYM62_01335	COG3344	reverse transcriptase
GYM62_01350	COG4974	Belongs to the 'phage' integrase family
GYM62_01355	COG2826	transposase and inactivated derivatives, IS30 family
GYM62_01375	COG1940	carbohydrate kinase activity
GYM62_01380	COG0363	glucosamine-6-phosphate deaminase activity
GYM62_01390	COG3265	gluconokinase activity
GYM62_01395	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GYM62_01425	COG1472	Belongs to the glycosyl hydrolase 3 family
GYM62_01430	COG2211	Major facilitator Superfamily
GYM62_01440	COG1649	PFAM Uncharacterised BCR, COG1649
GYM62_01450	COG1349	DNA-binding transcription factor activity
GYM62_01455	COG2366	antibiotic biosynthetic process
GYM62_01465	COG2010	Cytochrome c
GYM62_01495	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GYM62_01520	COG3842	ATPase activity
GYM62_01530	COG2226	methyltransferase
GYM62_01540	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GYM62_01545	COG0590	tRNA wobble adenosine to inosine editing
GYM62_01550	COG3279	Response regulator of the LytR AlgR family
GYM62_01555	COG3275	phosphorelay sensor kinase activity
GYM62_01565	COG0022	dehydrogenase e1 component
GYM62_01565	COG0508	dehydrogenase complex catalyzes the overall conversion of
GYM62_01570	COG1012	belongs to the aldehyde dehydrogenase family
GYM62_01575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GYM62_01585	COG0124	histidyl-tRNA synthetase
GYM62_01615	COG4771	TonB-dependent receptor
GYM62_01635	COG1446	asparaginase
GYM62_01640	COG3142	Participates in the control of copper homeostasis
GYM62_01660	COG0193	aminoacyl-tRNA hydrolase activity
GYM62_01665	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GYM62_01670	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GYM62_01705	COG0359	binds to the 23S rRNA
GYM62_01710	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GYM62_01715	COG0360	Binds together with S18 to 16S ribosomal RNA
GYM62_01735	COG2967	ApaG domain
GYM62_01740	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GYM62_01750	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GYM62_01760	COG1475	DNA binding
GYM62_01765	COG1192	Involved in chromosome partitioning
GYM62_01770	COG0706	membrane insertase activity
GYM62_01775	COG0504	CTP synthase activity
GYM62_01795	COG0517	IMP dehydrogenase activity
GYM62_01795	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GYM62_01795	COG0617	tRNA 3'-terminal CCA addition
GYM62_01815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GYM62_01820	COG2884	Cell division ATP-binding protein ftsE
GYM62_01830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GYM62_01855	COG4771	TonB-dependent receptor
GYM62_01870	COG4771	TonB-dependent receptor
GYM62_01920	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GYM62_01925	COG0732	type I restriction modification DNA specificity domain
GYM62_01930	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GYM62_01940	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GYM62_01985	COG4206	TonB-dependent receptor
GYM62_01985	COG1629	transport
GYM62_02035	COG3023	N-Acetylmuramoyl-L-alanine amidase
GYM62_02125	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GYM62_02140	COG3119	arylsulfatase activity
GYM62_02145	COG0745	RESPONSE REGULATOR receiver
GYM62_02145	COG2205	protein histidine kinase activity
GYM62_02145	COG3292	Two component regulator propeller
GYM62_02150	COG1629	transport
GYM62_02155	COG4771	TonB-dependent receptor
GYM62_02160	COG0702	epimerase
GYM62_02165	COG3119	arylsulfatase activity
GYM62_02175	COG3119	arylsulfatase activity
GYM62_02180	COG1295	ribonuclease BN
GYM62_02190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GYM62_02195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYM62_02200	COG0494	nUDIX hydrolase
GYM62_02205	COG0009	L-threonylcarbamoyladenylate synthase
GYM62_02215	COG0542	response to heat
GYM62_02230	COG1796	DNA polymerase
GYM62_02230	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GYM62_02245	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GYM62_02250	COG0540	Belongs to the ATCase OTCase family
GYM62_02260	COG1131	(ABC) transporter
GYM62_02285	COG0539	negative regulation of cytoplasmic translation
GYM62_02285	COG2183	response to ionizing radiation
GYM62_02300	COG0437	4 iron, 4 sulfur cluster binding
GYM62_02330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GYM62_02335	COG1612	heme a metabolic process
GYM62_02340	COG0109	protoheme IX farnesyltransferase activity
GYM62_02350	COG1845	cytochrome c oxidase, subunit III
GYM62_02365	COG2322	membrane
GYM62_02375	COG5000	phosphorelay sensor kinase activity
GYM62_02385	COG0300	oxidoreductase activity
GYM62_02390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GYM62_02405	COG0488	(ABC) transporter
GYM62_02410	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GYM62_02415	COG2205	protein histidine kinase activity
GYM62_02420	COG2205	protein histidine kinase activity
GYM62_02420	COG0784	Response regulator, receiver
GYM62_02425	COG1136	(ABC) transporter
GYM62_02440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GYM62_02455	COG1999	signal sequence binding
GYM62_02460	COG1981	membrane
GYM62_02470	COG1703	isobutyryl-CoA mutase activity
GYM62_02490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYM62_02495	COG1120	ATPase activity
GYM62_02505	COG0492	ferredoxin-NADP+ reductase activity
GYM62_02510	COG0633	Ferredoxin
GYM62_02525	COG2851	Citrate transporter
GYM62_02545	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GYM62_02545	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GYM62_02550	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GYM62_02555	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GYM62_02565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GYM62_02570	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GYM62_02575	COG0750	zinc metalloprotease
GYM62_02595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GYM62_02600	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GYM62_02605	COG1028	Short-chain dehydrogenase reductase Sdr
GYM62_02615	COG1278	Cold shock
GYM62_02620	COG0071	Belongs to the small heat shock protein (HSP20) family
GYM62_02630	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GYM62_02635	COG0740	serine-type endopeptidase activity
GYM62_02640	COG0544	peptidyl-prolyl cis-trans isomerase activity
GYM62_02650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GYM62_02655	COG0735	belongs to the Fur family
GYM62_02660	COG1366	Belongs to the anti-sigma-factor antagonist family
GYM62_02665	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GYM62_02700	COG2217	Heavy metal translocating P-type atpase
GYM62_02720	COG2010	Cytochrome c
GYM62_02725	COG0348	domain, Protein
GYM62_02740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GYM62_02750	COG2304	oxidoreductase activity
GYM62_02780	COG1131	(ABC) transporter
GYM62_02785	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GYM62_02790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GYM62_02790	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GYM62_02795	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GYM62_02800	COG1078	dGTPase activity
GYM62_02810	COG0802	atpase or kinase
GYM62_02815	COG0686	Belongs to the AlaDH PNT family
GYM62_02855	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GYM62_02870	COG0481	GTPase activity
GYM62_02880	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GYM62_02895	COG2205	protein histidine kinase activity
GYM62_02895	COG0784	Response regulator, receiver
GYM62_02900	COG2204	response regulator
GYM62_02930	COG0525	valine-tRNA ligase activity
GYM62_02940	COG4771	TonB-dependent receptor
GYM62_02955	COG1115	amino acid carrier protein
GYM62_02995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GYM62_03045	COG0629	single-stranded DNA binding
GYM62_03065	COG2755	lipolytic protein G-D-S-L family
GYM62_03065	COG0657	acetylesterase activity
GYM62_03075	COG0352	thiamine-phosphate diphosphorylase activity
GYM62_03085	COG2226	methyltransferase
GYM62_03095	COG0738	Major facilitator superfamily
GYM62_03100	COG1028	Short-chain dehydrogenase reductase Sdr
GYM62_03110	COG0179	Fumarylacetoacetate (FAA) hydrolase
GYM62_03115	COG1028	Short-chain dehydrogenase reductase Sdr
GYM62_03130	COG0784	Response regulator, receiver
GYM62_03135	COG4251	negative regulation of phosphorylation
GYM62_03140	COG4251	negative regulation of phosphorylation
GYM62_03145	COG0673	inositol 2-dehydrogenase activity
GYM62_03150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GYM62_03165	COG2382	esterase
GYM62_03175	COG0628	permease
GYM62_03180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GYM62_03180	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GYM62_03195	COG1401	restriction endodeoxyribonuclease activity
GYM62_03235	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GYM62_03240	COG2706	6-phosphogluconolactonase activity
GYM62_03250	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GYM62_03255	COG3279	Response regulator of the LytR AlgR family
GYM62_03280	COG4974	Belongs to the 'phage' integrase family
GYM62_03355	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYM62_03410	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GYM62_03430	COG0375	protein maturation
GYM62_03435	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GYM62_03440	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GYM62_03445	COG0298	carbon dioxide binding
GYM62_03500	COG2003	Belongs to the UPF0758 family
GYM62_03505	COG0629	single-stranded DNA binding
GYM62_03515	COG0513	Belongs to the DEAD box helicase family
GYM62_03535	COG0477	Major facilitator Superfamily
GYM62_03545	COG0671	phosphoesterase, PA-phosphatase related
GYM62_03550	COG0408	coproporphyrinogen oxidase activity
GYM62_03560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GYM62_03585	COG2151	metal-sulfur cluster biosynthetic enzyme
GYM62_03590	COG2166	iron-sulfur cluster assembly
GYM62_03595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GYM62_03600	COG0719	Fe-S assembly protein
GYM62_03605	COG0396	ATPase activity
GYM62_03610	COG0719	Fe-S assembly protein
GYM62_03615	COG1522	sequence-specific DNA binding
GYM62_03630	COG0823	Involved in the tonB-independent uptake of proteins
GYM62_03630	COG1506	peptidase
GYM62_03635	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GYM62_03700	COG0463	Glycosyl transferase, family 2
GYM62_03700	COG1216	Glycosyl transferase, family 2
GYM62_03720	COG0438	transferase activity, transferring glycosyl groups
GYM62_03725	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GYM62_03740	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GYM62_03750	COG0489	protein tyrosine kinase activity
GYM62_03770	COG0463	Glycosyl transferase, family 2
GYM62_03770	COG1216	Glycosyl transferase, family 2
GYM62_03775	COG0367	asparagine synthase
GYM62_03780	COG0297	glycogen (starch) synthase activity
GYM62_03780	COG0438	transferase activity, transferring glycosyl groups
GYM62_03790	COG0367	asparagine synthase
GYM62_03805	COG0438	transferase activity, transferring glycosyl groups
GYM62_03810	COG0367	asparagine synthase
GYM62_03825	COG0438	transferase activity, transferring glycosyl groups
GYM62_03845	COG1063	alcohol dehydrogenase
GYM62_03860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GYM62_03865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GYM62_03895	COG3291	Pkd domain containing protein
GYM62_03935	COG3344	reverse transcriptase
GYM62_03970	COG0463	Glycosyl transferase, family 2
GYM62_03990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GYM62_04015	COG0110	maltose O-acetyltransferase activity
GYM62_04025	COG3754	Rhamnan synthesis protein F
GYM62_04030	COG0463	Glycosyl transferase, family 2
GYM62_04030	COG1216	Glycosyl transferase, family 2
GYM62_04045	COG0463	Glycosyl transferase, family 2
GYM62_04045	COG1216	Glycosyl transferase, family 2
GYM62_04055	COG0463	Glycosyl transferase, family 2
GYM62_04055	COG1216	Glycosyl transferase, family 2
GYM62_04070	COG0438	transferase activity, transferring glycosyl groups
GYM62_04080	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GYM62_04080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GYM62_04090	COG0438	transferase activity, transferring glycosyl groups
GYM62_04110	COG1629	transport
GYM62_04110	COG4206	TonB-dependent receptor
GYM62_04125	COG0438	transferase activity, transferring glycosyl groups
GYM62_04150	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GYM62_04170	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYM62_04175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GYM62_04200	COG3599	regulation of cell shape
GYM62_04205	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GYM62_04205	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GYM62_04220	COG0316	Belongs to the HesB IscA family
GYM62_04240	COG0702	epimerase
GYM62_04245	COG1490	D-aminoacyl-tRNA deacylase activity
GYM62_04250	COG1119	ATPase activity
GYM62_04265	COG1694	Mazg nucleotide pyrophosphohydrolase
GYM62_04285	COG2045	Belongs to the ComB family
GYM62_04290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GYM62_04295	COG0316	Belongs to the HesB IscA family
GYM62_04300	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GYM62_04300	COG1082	Xylose isomerase domain protein TIM barrel
GYM62_04305	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GYM62_04315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GYM62_04325	COG1028	Short-chain dehydrogenase reductase Sdr
GYM62_04330	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GYM62_04330	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GYM62_04350	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GYM62_04355	COG0247	lactate metabolic process
GYM62_04355	COG0277	FAD linked oxidase domain protein
GYM62_04370	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GYM62_04375	COG1228	amidohydrolase
GYM62_04380	COG2986	histidine ammonia-lyase
GYM62_04385	COG0583	DNA-binding transcription factor activity
GYM62_04400	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GYM62_04410	COG2050	protein possibly involved in aromatic compounds catabolism
GYM62_04415	COG0406	alpha-ribazole phosphatase activity
GYM62_04430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GYM62_04435	COG1663	tetraacyldisaccharide 4'-kinase activity
GYM62_04450	COG0577	efflux transmembrane transporter activity
GYM62_04470	COG3655	Transcriptional regulator
GYM62_04500	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GYM62_04510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GYM62_04520	COG1629	transport
GYM62_04535	COG1940	carbohydrate kinase activity
GYM62_04540	COG0445	tRNA wobble uridine modification
GYM62_04595	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GYM62_04620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GYM62_04625	COG0303	'Molybdopterin
GYM62_04630	COG0730	response to heat
GYM62_04640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GYM62_04645	COG0314	molybdopterin synthase activity
GYM62_04655	COG0521	Mo-molybdopterin cofactor biosynthetic process
GYM62_04655	COG0315	cyclic pyranopterin monophosphate synthase activity
GYM62_04695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYM62_04700	COG2183	response to ionizing radiation
GYM62_04715	COG2826	transposase and inactivated derivatives, IS30 family
GYM62_04725	COG1943	Transposase
GYM62_04735	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GYM62_04750	COG3620	sequence-specific DNA binding
GYM62_04800	COG3119	arylsulfatase activity
GYM62_04815	COG1940	carbohydrate kinase activity
GYM62_04835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GYM62_04840	COG2135	peptidase activity
GYM62_04845	COG0429	hydrolase of the alpha beta-hydrolase fold
GYM62_04855	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GYM62_04875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GYM62_04890	COG0667	Aldo Keto reductase
GYM62_04895	COG1288	antiporter activity
GYM62_04905	COG2072	flavoprotein involved in K transport
GYM62_04915	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GYM62_04925	COG2062	phosphohistidine phosphatase, SixA
GYM62_04950	COG5520	Belongs to the glycosyl hydrolase 30 family
GYM62_04965	COG0793	Belongs to the peptidase S41A family
GYM62_04965	COG4946	Tricorn protease homolog
GYM62_05095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GYM62_05105	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GYM62_05115	COG0179	Fumarylacetoacetate (FAA) hydrolase
GYM62_05125	COG1619	proteins homologs of microcin C7 resistance protein MccF
GYM62_05135	COG2363	Small membrane protein
GYM62_05155	COG0686	Belongs to the AlaDH PNT family
GYM62_05160	COG0022	dehydrogenase e1 component
GYM62_05175	COG2204	response regulator
GYM62_05185	COG4772	TonB-dependent receptor
GYM62_05210	COG2326	polyphosphate kinase activity
GYM62_05215	COG1404	Belongs to the peptidase S8 family
GYM62_05220	COG1404	Belongs to the peptidase S8 family
GYM62_05230	COG0587	DNA-directed DNA polymerase activity
GYM62_05245	COG2205	protein histidine kinase activity
GYM62_05245	COG4191	Histidine kinase
GYM62_05245	COG0745	RESPONSE REGULATOR receiver
GYM62_05270	COG2514	catechol 2,3-dioxygenase activity
GYM62_05275	COG3661	Belongs to the glycosyl hydrolase 67 family
GYM62_05280	COG1074	ATP-dependent DNA helicase activity
GYM62_05300	COG0251	oxidation-reduction process
GYM62_05305	COG0456	acetyltransferase
GYM62_05315	COG1283	sodium-dependent phosphate transmembrane transporter activity
GYM62_05325	COG1511	domain protein
GYM62_05325	COG3264	Mechanosensitive ion channel
GYM62_05330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GYM62_05330	COG3153	acetyltransferase
GYM62_05335	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GYM62_05340	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GYM62_05345	COG2989	Protein conserved in bacteria
GYM62_05360	COG0302	gtp cyclohydrolase
GYM62_05365	COG1028	Short-chain dehydrogenase reductase Sdr
GYM62_05395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GYM62_05395	COG0519	Catalyzes the synthesis of GMP from XMP
GYM62_05405	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GYM62_05415	COG1393	Belongs to the ArsC family
GYM62_05420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GYM62_05425	COG0156	8-amino-7-oxononanoate synthase activity
GYM62_05430	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GYM62_05435	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GYM62_05450	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GYM62_05465	COG0442	prolyl-tRNA aminoacylation
GYM62_05475	COG4864	UPF0365 protein
GYM62_05485	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GYM62_05525	COG1215	transferase activity, transferring glycosyl groups
GYM62_05570	COG0673	inositol 2-dehydrogenase activity
GYM62_05600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GYM62_05635	COG4807	Protein conserved in bacteria
GYM62_05660	COG2217	Heavy metal translocating P-type atpase
GYM62_05665	COG2207	Transcriptional regulator
GYM62_05680	COG0318	PFAM AMP-dependent synthetase and ligase
GYM62_05695	COG1760	l-serine dehydratase
GYM62_05700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GYM62_05710	COG1070	Carbohydrate kinase
GYM62_05715	COG2115	Belongs to the xylose isomerase family
GYM62_05745	COG2329	Antibiotic biosynthesis monooxygenase
GYM62_05780	COG0656	L-ascorbic acid biosynthetic process
GYM62_05800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GYM62_05815	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GYM62_05845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GYM62_05850	COG0589	response to stress
GYM62_05880	COG0811	peptide transport
GYM62_05885	COG0848	biopolymer transport protein
GYM62_05900	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GYM62_05905	COG2205	protein histidine kinase activity
GYM62_05905	COG0784	Response regulator, receiver
GYM62_05910	COG1024	Enoyl-CoA hydratase
GYM62_05910	COG1250	3-hydroxyacyl-CoA dehydrogenase
GYM62_05925	COG1028	Short-chain dehydrogenase reductase Sdr
GYM62_05930	COG1063	alcohol dehydrogenase
GYM62_05995	COG0732	type I restriction modification DNA specificity domain
GYM62_06005	COG1960	acyl-CoA dehydrogenase activity
GYM62_06045	COG0405	Gamma-glutamyltransferase
GYM62_06050	COG0823	Involved in the tonB-independent uptake of proteins
GYM62_06050	COG1506	peptidase
GYM62_06070	COG1428	Deoxynucleoside kinase
GYM62_06075	COG1250	3-hydroxyacyl-CoA dehydrogenase
GYM62_06080	COG2996	Protein conserved in bacteria
GYM62_06130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GYM62_06135	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GYM62_06145	COG1309	transcriptional regulator
GYM62_06150	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GYM62_06155	COG0823	Involved in the tonB-independent uptake of proteins
GYM62_06170	COG1950	PFAM Membrane protein of
GYM62_06185	COG0123	including yeast histone deacetylase and acetoin utilization protein
GYM62_06200	COG3047	cAMP biosynthetic process
GYM62_06200	COG2885	chlorophyll binding
GYM62_06215	COG1115	amino acid carrier protein
GYM62_06220	COG1929	Belongs to the glycerate kinase type-1 family
GYM62_06240	COG3279	Response regulator of the LytR AlgR family
GYM62_06260	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GYM62_06270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GYM62_06280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GYM62_06290	COG3250	beta-galactosidase activity
GYM62_06295	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GYM62_06320	COG1301	dicarboxylic acid transport
GYM62_06325	COG3360	Dodecin
GYM62_06350	COG0531	amino acid
GYM62_06365	COG0436	Aminotransferase
GYM62_06400	COG3239	Fatty acid desaturase
GYM62_06405	COG0006	proline dipeptidase activity
GYM62_06535	COG4206	TonB-dependent receptor
GYM62_06535	COG1629	transport
GYM62_06570	COG1196	nuclear chromosome segregation
GYM62_06585	COG0723	plastoquinol--plastocyanin reductase activity
GYM62_06615	COG0791	NLP P60 protein
GYM62_06620	COG1228	amidohydrolase
GYM62_06625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GYM62_06635	COG0745	RESPONSE REGULATOR receiver
GYM62_06675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GYM62_06690	COG1473	amidohydrolase
GYM62_06705	COG0513	Belongs to the DEAD box helicase family
GYM62_06715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GYM62_06745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GYM62_06770	COG1132	(ABC) transporter
GYM62_06870	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GYM62_06875	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GYM62_06880	COG0196	riboflavin kinase activity
GYM62_06885	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GYM62_06895	COG2177	Part of the ABC transporter FtsEX involved in
GYM62_06910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GYM62_06915	COG2873	o-acetylhomoserine
GYM62_06920	COG0288	reversible hydration of carbon dioxide
GYM62_06930	COG0165	Argininosuccinate lyase
GYM62_06935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GYM62_06940	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GYM62_06955	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GYM62_06960	COG0137	argininosuccinate synthase activity
GYM62_06970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GYM62_06980	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GYM62_07025	COG1643	Atp-dependent helicase
GYM62_07035	COG0673	inositol 2-dehydrogenase activity
GYM62_07065	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GYM62_07075	COG1733	regulation of RNA biosynthetic process
GYM62_07080	COG1104	cysteine desulfurase activity
GYM62_07085	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GYM62_07090	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GYM62_07120	COG0471	metal ion transport
GYM62_07125	COG3275	phosphorelay sensor kinase activity
GYM62_07130	COG3279	Response regulator of the LytR AlgR family
GYM62_07140	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GYM62_07145	COG1082	Xylose isomerase domain protein TIM barrel
GYM62_07150	COG0673	inositol 2-dehydrogenase activity
GYM62_07180	COG1678	Uncharacterized ACR, COG1678
GYM62_07185	COG0259	pyridoxamine-phosphate oxidase activity
GYM62_07195	COG0739	heme binding
GYM62_07200	COG0492	ferredoxin-NADP+ reductase activity
GYM62_07205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GYM62_07210	COG1185	polyribonucleotide nucleotidyltransferase activity
GYM62_07215	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GYM62_07245	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GYM62_07250	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GYM62_07255	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GYM62_07260	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GYM62_07275	COG0579	oxidoreductase
GYM62_07280	COG0069	glutamate synthase activity
GYM62_07295	COG2081	HI0933 family
GYM62_07300	COG0433	COG0433 Predicted ATPase
GYM62_07320	COG2171	N-acyltransferase activity
GYM62_07335	COG0803	Belongs to the bacterial solute-binding protein 9 family
GYM62_07340	COG1121	(ABC) transporter
GYM62_07345	COG1321	iron dependent repressor
GYM62_07345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GYM62_07350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GYM62_07360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GYM62_07370	COG4916	TIR domain
GYM62_07420	COG1126	abc transporter atp-binding protein
GYM62_07425	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GYM62_07435	COG1819	glycosyl
GYM62_07440	COG1621	beta-fructofuranosidase activity
GYM62_07455	COG0733	neurotransmitter:sodium symporter activity
GYM62_07465	COG2249	NAD(P)H dehydrogenase (quinone) activity
GYM62_07480	COG2340	Cysteine-rich secretory protein family
GYM62_07495	COG0482	sulfurtransferase activity
GYM62_07500	COG0564	pseudouridine synthase activity
GYM62_07510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GYM62_07520	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GYM62_07525	COG2086	electron transfer activity
GYM62_07540	COG0604	alcohol dehydrogenase
GYM62_07545	COG0305	Participates in initiation and elongation during chromosome replication
GYM62_07555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GYM62_07585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GYM62_07600	COG0384	phenazine biosynthesis protein PhzF
GYM62_07615	COG1528	Iron-storage protein
GYM62_07635	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GYM62_07645	COG0307	riboflavin synthase, alpha
GYM62_07650	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GYM62_07665	COG2814	Major facilitator Superfamily
GYM62_07675	COG0424	maF-like protein
GYM62_07685	COG0439	Biotin carboxylase
GYM62_07690	COG0156	8-amino-7-oxononanoate synthase activity
GYM62_07710	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GYM62_07715	COG0531	amino acid
GYM62_07735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GYM62_07740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYM62_07745	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GYM62_07750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GYM62_07765	COG2201	protein-glutamate methylesterase activity
GYM62_07790	COG0010	Belongs to the arginase family
GYM62_07795	COG0018	arginyl-trna synthetase
GYM62_07800	COG0386	Belongs to the glutathione peroxidase family
GYM62_07805	COG1575	Belongs to the MenA family. Type 1 subfamily
GYM62_07810	COG0589	response to stress
GYM62_07825	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GYM62_07830	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GYM62_07835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GYM62_07840	COG0131	Imidazoleglycerol-phosphate dehydratase
GYM62_07840	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GYM62_07855	COG0463	Glycosyl transferase, family 2
GYM62_07860	COG0577	efflux transmembrane transporter activity
GYM62_07865	COG3876	Protein conserved in bacteria
GYM62_07870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GYM62_07880	COG0300	oxidoreductase activity
GYM62_07885	COG1546	Belongs to the CinA family
GYM62_07885	COG1058	Belongs to the CinA family
GYM62_07890	COG0508	dehydrogenase complex catalyzes the overall conversion of
GYM62_07895	COG0784	Response regulator, receiver
GYM62_07895	COG2205	protein histidine kinase activity
GYM62_07915	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GYM62_07915	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GYM62_07915	COG1703	isobutyryl-CoA mutase activity
GYM62_07920	COG0427	acetyl-CoA hydrolase
GYM62_07925	COG2814	Major facilitator Superfamily
GYM62_07950	COG1793	dna ligase
GYM62_07955	COG1201	RNA secondary structure unwinding
GYM62_07960	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GYM62_07980	COG1914	H( )-stimulated, divalent metal cation uptake system
GYM62_08000	COG1970	mechanosensitive ion channel activity
GYM62_08005	COG1770	oligopeptidase
GYM62_08010	COG1803	Methylglyoxal synthase
GYM62_08015	COG0205	6-phosphofructokinase activity
GYM62_08030	COG2814	Major facilitator Superfamily
GYM62_08045	COG0534	Mate efflux family protein
GYM62_08055	COG1522	sequence-specific DNA binding
GYM62_08075	COG0415	Belongs to the DNA photolyase family
GYM62_08100	COG0730	response to heat
GYM62_08105	COG0589	response to stress
GYM62_08110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GYM62_08160	COG2321	neutral zinc metallopeptidase
GYM62_08190	COG4206	TonB-dependent receptor
GYM62_08195	COG2304	oxidoreductase activity
GYM62_08210	COG0183	Belongs to the thiolase family
GYM62_08220	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GYM62_08230	COG1234	tRNA 3'-trailer cleavage
GYM62_08235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GYM62_08240	COG0513	Belongs to the DEAD box helicase family
GYM62_08255	COG0758	DNA mediated transformation
GYM62_08255	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GYM62_08285	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GYM62_08290	COG0646	methionine synthase
GYM62_08290	COG1410	methionine synthase
GYM62_08305	COG0784	Response regulator, receiver
GYM62_08305	COG2205	protein histidine kinase activity
GYM62_08310	COG0393	Putative heavy-metal-binding
GYM62_08335	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GYM62_08345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GYM62_08375	COG1030	water channel activity
GYM62_08390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GYM62_08400	COG1136	(ABC) transporter
GYM62_08410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GYM62_08415	COG2235	arginine
GYM62_08425	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GYM62_08435	COG1605	Chorismate mutase
GYM62_08435	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GYM62_08440	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GYM62_08445	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GYM62_08450	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GYM62_08455	COG0077	Prephenate dehydratase
GYM62_08455	COG1605	Chorismate mutase
GYM62_08460	COG0436	Aminotransferase
GYM62_08530	COG4771	TonB-dependent receptor
GYM62_08535	COG1321	iron dependent repressor
GYM62_08540	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GYM62_08545	COG3279	Response regulator of the LytR AlgR family
GYM62_08565	COG0436	Aminotransferase
GYM62_08575	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GYM62_08585	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GYM62_08590	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GYM62_08595	COG1984	allophanate hydrolase subunit 2
GYM62_08605	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GYM62_08605	COG0116	Belongs to the methyltransferase superfamily
GYM62_08620	COG4771	TonB-dependent receptor
GYM62_08630	COG1609	Transcriptional regulator
GYM62_08635	COG1904	glucuronate isomerase
GYM62_08640	COG1028	Short-chain dehydrogenase reductase Sdr
GYM62_08645	COG1312	Catalyzes the dehydration of D-mannonate
GYM62_08650	COG0110	maltose O-acetyltransferase activity
GYM62_08655	COG1960	acyl-CoA dehydrogenase activity
GYM62_08660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GYM62_08670	COG0318	PFAM AMP-dependent synthetase and ligase
GYM62_08675	COG1960	acyl-CoA dehydrogenase activity
GYM62_08695	COG1335	isochorismatase
GYM62_08700	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GYM62_08740	COG1136	(ABC) transporter
GYM62_08745	COG0045	succinate-CoA ligase (ADP-forming) activity
GYM62_08765	COG0471	metal ion transport
GYM62_08765	COG3273	potassium ion transport
GYM62_08775	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GYM62_08780	COG0187	DNA topoisomerase II activity
GYM62_08820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GYM62_08820	COG0116	Belongs to the methyltransferase superfamily
GYM62_08825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GYM62_08845	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GYM62_08855	COG0667	Aldo Keto reductase
GYM62_08860	COG0205	6-phosphofructokinase activity
GYM62_08870	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GYM62_08875	COG4999	Histidine kinase
GYM62_08875	COG3850	Histidine kinase
GYM62_08875	COG3437	response regulator, receiver
GYM62_08875	COG2205	protein histidine kinase activity
GYM62_08890	COG0321	lipoyl(octanoyl) transferase activity
GYM62_08890	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GYM62_08895	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GYM62_08905	COG3279	Response regulator of the LytR AlgR family
GYM62_08910	COG3275	phosphorelay sensor kinase activity
GYM62_08915	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GYM62_08930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GYM62_08935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GYM62_08940	COG0571	ribonuclease III activity
GYM62_08945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GYM62_08945	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GYM62_08950	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GYM62_08955	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GYM62_08985	COG0339	signal peptide processing
GYM62_08990	COG0628	permease
GYM62_09000	COG2205	protein histidine kinase activity
GYM62_09000	COG0784	Response regulator, receiver
GYM62_09020	COG2031	fatty acid transporter
GYM62_09030	COG2205	protein histidine kinase activity
GYM62_09040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GYM62_09045	COG4251	negative regulation of phosphorylation
GYM62_09050	COG2204	response regulator
GYM62_09060	COG0628	permease
GYM62_09065	COG0012	GTP binding
GYM62_09085	COG0488	(ABC) transporter
GYM62_09095	COG1199	ATP-dependent helicase activity
GYM62_09095	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GYM62_09100	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GYM62_09110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GYM62_09115	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GYM62_09120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GYM62_09130	COG4771	TonB-dependent receptor
GYM62_09145	COG3023	N-Acetylmuramoyl-L-alanine amidase
GYM62_09205	COG1629	transport
GYM62_09205	COG4206	TonB-dependent receptor
GYM62_09250	COG2801	Transposase and inactivated derivatives
GYM62_09300	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GYM62_09370	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GYM62_09380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GYM62_09395	COG0662	Cupin 2, conserved barrel domain protein
GYM62_09395	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GYM62_09415	COG0489	protein tyrosine kinase activity
GYM62_09415	COG3206	protein involved in exopolysaccharide biosynthesis
GYM62_09425	COG0366	Alpha amylase catalytic
GYM62_09435	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GYM62_09445	COG1609	Transcriptional regulator
GYM62_09475	COG2205	protein histidine kinase activity
GYM62_09475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GYM62_09475	COG2198	Histidine kinase
GYM62_09475	COG0784	Response regulator, receiver
GYM62_09480	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GYM62_09490	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GYM62_09490	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GYM62_09495	COG0358	DNA primase activity
GYM62_09500	COG0489	protein tyrosine kinase activity
GYM62_09505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GYM62_09525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GYM62_09535	COG1011	Hydrolase
GYM62_09580	COG0697	spore germination
GYM62_09595	COG1573	uracil-dna glycosylase
GYM62_09620	COG1136	(ABC) transporter
GYM62_09625	COG4591	ABC-type transport system involved in lipoprotein release permease component
GYM62_09635	COG0577	efflux transmembrane transporter activity
GYM62_09640	COG3781	membrane
GYM62_09655	COG0577	efflux transmembrane transporter activity
GYM62_09660	COG1136	(ABC) transporter
GYM62_09660	COG0577	efflux transmembrane transporter activity
GYM62_09675	COG2204	response regulator
GYM62_09680	COG4191	Histidine kinase
GYM62_09690	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GYM62_09710	COG0732	type I restriction modification DNA specificity domain
GYM62_09765	COG1752	Esterase of the alpha-beta hydrolase superfamily
GYM62_09770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYM62_09775	COG0825	malonyl-CoA metabolic process
GYM62_09790	COG0405	Gamma-glutamyltransferase
GYM62_09820	COG0488	(ABC) transporter
GYM62_09830	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GYM62_09845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GYM62_09850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GYM62_09855	COG2239	Acts as a magnesium transporter
GYM62_09860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GYM62_09865	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GYM62_09875	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GYM62_09880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GYM62_09885	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GYM62_09890	COG0511	ligase activity, forming carbon-carbon bonds
GYM62_09895	COG0439	Biotin carboxylase
GYM62_09930	COG2826	transposase and inactivated derivatives, IS30 family
GYM62_09985	COG0629	single-stranded DNA binding
GYM62_10030	COG2308	Evidence 4 Homologs of previously reported genes of
GYM62_10035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GYM62_10040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GYM62_10040	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GYM62_10050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GYM62_10055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GYM62_10060	COG1570	exodeoxyribonuclease VII activity
GYM62_10080	COG1132	(ABC) transporter
GYM62_10085	COG0861	Integral membrane protein TerC family
GYM62_10095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GYM62_10115	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GYM62_10120	COG1051	belongs to the nudix hydrolase family
GYM62_10125	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GYM62_10140	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GYM62_10160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GYM62_10170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GYM62_10170	COG0512	Glutamine amidotransferase of anthranilate synthase
GYM62_10175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GYM62_10180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GYM62_10215	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GYM62_10220	COG0459	protein refolding
GYM62_10225	COG2201	protein-glutamate methylesterase activity
GYM62_10240	COG1228	amidohydrolase
GYM62_10255	COG2388	GCN5-related N-acetyl-transferase
GYM62_10275	COG4654	Cytochrome c, class I
GYM62_10320	COG5002	protein histidine kinase activity
GYM62_10325	COG0745	RESPONSE REGULATOR receiver
GYM62_10340	COG2267	carboxylic ester hydrolase activity
GYM62_10355	COG2826	transposase and inactivated derivatives, IS30 family
GYM62_10365	COG3023	N-Acetylmuramoyl-L-alanine amidase
GYM62_10420	COG0702	epimerase
GYM62_10425	COG1629	transport
GYM62_10425	COG4206	TonB-dependent receptor
GYM62_10590	COG2217	Heavy metal translocating P-type atpase
GYM62_10605	COG1742	UPF0060 membrane protein
GYM62_10680	COG0347	Belongs to the P(II) protein family
GYM62_10720	COG2132	Multicopper oxidase
GYM62_10725	COG2226	methyltransferase
GYM62_10755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GYM62_10775	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GYM62_10805	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GYM62_10810	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GYM62_10815	COG0298	carbon dioxide binding
GYM62_10820	COG0409	Hydrogenase expression formation protein
GYM62_10825	COG0309	Hydrogenase expression formation protein (HypE)
GYM62_10845	COG0375	protein maturation
GYM62_10865	COG3344	reverse transcriptase
GYM62_10880	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GYM62_10900	COG1120	ATPase activity
GYM62_10905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYM62_10930	COG4115	mRNA cleavage
GYM62_10935	COG2161	toxin-antitoxin pair type II binding
GYM62_10955	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GYM62_11040	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GYM62_11045	COG4771	TonB-dependent receptor
GYM62_11060	COG0823	Involved in the tonB-independent uptake of proteins
GYM62_11060	COG4946	Tricorn protease homolog
GYM62_11060	COG1506	peptidase
GYM62_11080	COG1595	DNA-templated transcription, initiation
GYM62_11100	COG1331	Highly conserved protein containing a thioredoxin domain
GYM62_11105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GYM62_11130	COG4591	ABC-type transport system involved in lipoprotein release permease component
GYM62_11135	COG1136	(ABC) transporter
GYM62_11140	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GYM62_11165	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GYM62_11175	COG2610	gluconate transmembrane transporter activity
GYM62_11190	COG2361	Protein of unknown function DUF86
GYM62_11195	COG1028	Short-chain dehydrogenase reductase Sdr
GYM62_11230	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GYM62_11235	COG0531	amino acid
GYM62_11260	COG4974	Belongs to the 'phage' integrase family
GYM62_11265	COG0517	IMP dehydrogenase activity
GYM62_11275	COG0517	IMP dehydrogenase activity
GYM62_11300	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GYM62_11320	COG0656	L-ascorbic acid biosynthetic process
GYM62_11330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GYM62_11335	COG1538	Outer membrane efflux protein
GYM62_11345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GYM62_11380	COG0473	3-isopropylmalate dehydrogenase activity
GYM62_11385	COG1024	Enoyl-CoA hydratase
GYM62_11410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GYM62_11415	COG0154	amidase activity
GYM62_11420	COG1388	LysM domain
GYM62_11420	COG0741	lytic transglycosylase activity
GYM62_11430	COG0280	phosphate acetyltransferase
GYM62_11430	COG0281	malic enzyme
GYM62_11435	COG0632	four-way junction helicase activity
GYM62_11445	COG0509	glycine decarboxylation via glycine cleavage system
GYM62_11465	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GYM62_11470	COG1561	YicC-like family, N-terminal region
GYM62_11480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GYM62_11485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYM62_11490	COG1183	phosphatidylcholine synthase activity
GYM62_11510	COG1216	Glycosyl transferase, family 2
GYM62_11535	COG1757	Na H antiporter
GYM62_11570	COG1028	Short-chain dehydrogenase reductase Sdr
GYM62_11580	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GYM62_11590	COG0799	negative regulation of ribosome biogenesis
GYM62_11595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GYM62_11600	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GYM62_11620	COG4191	Histidine kinase
GYM62_11650	COG0823	Involved in the tonB-independent uptake of proteins
GYM62_11650	COG1506	peptidase
GYM62_11680	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GYM62_11700	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GYM62_11705	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GYM62_11715	COG0415	Belongs to the DNA photolyase family
GYM62_11720	COG1193	negative regulation of DNA recombination
GYM62_11730	COG0626	cystathionine gamma-synthase activity
GYM62_11750	COG1695	Transcriptional regulator
GYM62_11760	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GYM62_11800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GYM62_11805	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GYM62_11900	COG0732	type I restriction modification DNA specificity domain
GYM62_11905	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GYM62_11910	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GYM62_11950	COG0523	cobalamin synthesis protein
GYM62_11965	COG1476	TRANSCRIPTIONal
GYM62_12000	COG0702	epimerase
GYM62_12045	COG1131	(ABC) transporter
GYM62_12075	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GYM62_12095	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GYM62_12095	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GYM62_12100	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GYM62_12110	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GYM62_12115	COG1959	2 iron, 2 sulfur cluster binding
GYM62_12120	COG3119	arylsulfatase activity
GYM62_12140	COG4206	TonB-dependent receptor
GYM62_12140	COG1629	transport
GYM62_12150	COG1082	Xylose isomerase domain protein TIM barrel
GYM62_12185	COG3177	Filamentation induced by cAMP protein fic
GYM62_12230	COG4974	Belongs to the 'phage' integrase family
GYM62_12270	COG4974	Belongs to the 'phage' integrase family
GYM62_12275	COG0582	viral genome integration into host DNA
GYM62_12325	COG4974	Belongs to the 'phage' integrase family
GYM62_12365	COG4974	Belongs to the 'phage' integrase family
GYM62_12385	COG1395	domain, Protein
GYM62_12420	COG0673	inositol 2-dehydrogenase activity
GYM62_12470	COG1082	Xylose isomerase domain protein TIM barrel
GYM62_12475	COG4948	Mandelate Racemase Muconate Lactonizing
GYM62_12485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GYM62_12515	COG0659	secondary active sulfate transmembrane transporter activity
GYM62_12520	COG0477	Major facilitator Superfamily
GYM62_12530	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GYM62_12550	COG1629	transport
GYM62_12575	COG4771	TonB-dependent receptor
GYM62_12585	COG0602	queuosine metabolic process
GYM62_12595	COG1473	amidohydrolase
GYM62_12600	COG0495	leucyl-tRNA aminoacylation
GYM62_12650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GYM62_12650	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GYM62_12680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GYM62_12695	COG0513	Belongs to the DEAD box helicase family
GYM62_12700	COG3239	Fatty acid desaturase
GYM62_12710	COG3258	Cytochrome c
GYM62_12720	COG2223	nitrite transmembrane transporter activity
GYM62_12725	COG0392	lysyltransferase activity
GYM62_12740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYM62_12740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GYM62_12745	COG3118	belongs to the thioredoxin family
GYM62_12765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GYM62_12775	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GYM62_12775	COG0517	IMP dehydrogenase activity
GYM62_12780	COG0514	ATP-dependent DNA helicase (RecQ)
GYM62_12790	COG1774	PSP1 C-terminal conserved region
GYM62_12800	COG0166	Belongs to the GPI family
GYM62_12810	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GYM62_12825	COG1127	ABC transporter
GYM62_12830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GYM62_12850	COG2066	Belongs to the glutaminase family
GYM62_12855	COG1217	gtp-binding protein TYPA
GYM62_12865	COG0667	Aldo Keto reductase
GYM62_12880	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GYM62_12885	COG0138	bifunctional purine biosynthesis protein purh
GYM62_12895	COG1598	PFAM Uncharacterised protein family UPF0150
GYM62_12910	COG0215	cysteine-tRNA ligase activity
GYM62_12930	COG4654	Cytochrome c, class I
GYM62_12960	COG1272	protein, Hemolysin III
GYM62_12965	COG2267	carboxylic ester hydrolase activity
GYM62_13035	COG2354	Protein conserved in bacteria
GYM62_13045	COG0501	Belongs to the peptidase M48B family
GYM62_13060	COG3022	response to hydroperoxide
GYM62_13110	COG0017	Asparaginyl-tRNA synthetase
GYM62_13125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GYM62_13125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GYM62_13130	COG2270	Major facilitator Superfamily
GYM62_13150	COG0811	peptide transport
GYM62_13165	COG3250	beta-galactosidase activity
GYM62_13170	COG2211	Major facilitator Superfamily
GYM62_13175	COG3530	Putative quorum-sensing-regulated virulence factor
GYM62_13185	COG3550	peptidyl-serine autophosphorylation
GYM62_13190	COG3550	peptidyl-serine autophosphorylation
GYM62_13195	COG1396	sequence-specific DNA binding
GYM62_13205	COG0252	asparaginase activity
GYM62_13210	COG0084	hydrolase, TatD family'
GYM62_13235	COG1215	transferase activity, transferring glycosyl groups
GYM62_13240	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GYM62_13270	COG3457	Alanine racemase
GYM62_13285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GYM62_13290	COG1053	succinate dehydrogenase
GYM62_13305	COG3011	Protein conserved in bacteria
GYM62_13320	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GYM62_13330	COG0616	signal peptide processing
GYM62_13335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GYM62_13345	COG0006	proline dipeptidase activity
GYM62_13350	COG0612	Peptidase, M16
GYM62_13360	COG0791	NLP P60 protein
GYM62_13360	COG1388	LysM domain
GYM62_13360	COG3103	Sh3 type 3 domain protein
GYM62_13370	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GYM62_13395	COG0577	efflux transmembrane transporter activity
GYM62_13395	COG1136	(ABC) transporter
GYM62_13400	COG4181	ATPase activity
GYM62_13465	COG0733	neurotransmitter:sodium symporter activity
GYM62_13480	COG0181	hydroxymethylbilane synthase activity
GYM62_13485	COG0189	ligase activity
GYM62_13495	COG0470	DNA polymerase III
GYM62_13505	COG0254	rRNA binding
GYM62_13510	COG2885	chlorophyll binding
GYM62_13520	COG1132	(ABC) transporter
GYM62_13530	COG0606	chelatase, subunit chli
GYM62_13545	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GYM62_13565	COG1054	Belongs to the UPF0176 family
GYM62_13570	COG0626	cystathionine gamma-synthase activity
GYM62_13595	COG0101	tRNA pseudouridine synthase activity
GYM62_13600	COG1132	(ABC) transporter
GYM62_13620	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GYM62_13630	COG0633	Ferredoxin
GYM62_13630	COG3217	Mosc domain protein beta barrel domain protein
GYM62_13635	COG0443	Heat shock 70 kDa protein
GYM62_13640	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GYM62_13655	COG0004	ammonium transporteR
GYM62_13660	COG0113	porphobilinogen synthase activity
GYM62_13670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GYM62_13680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GYM62_13685	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GYM62_13695	COG0552	protein localization to endoplasmic reticulum
GYM62_13725	COG2226	methyltransferase
GYM62_13730	COG1216	Glycosyl transferase, family 2
GYM62_13735	COG0463	Glycosyl transferase, family 2
GYM62_13750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GYM62_13780	COG0673	inositol 2-dehydrogenase activity
GYM62_13785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GYM62_13795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GYM62_13800	COG0248	Ppx GppA phosphatase
GYM62_13810	COG0673	inositol 2-dehydrogenase activity
GYM62_13820	COG0022	dehydrogenase e1 component
GYM62_13835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GYM62_13860	COG2801	Transposase and inactivated derivatives
GYM62_13885	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GYM62_13890	COG0420	3'-5' exonuclease activity
GYM62_13895	COG0419	ATPase involved in DNA repair
GYM62_13905	COG0346	lactoylglutathione lyase activity
GYM62_13910	COG2353	YceI-like domain
GYM62_13940	COG1228	amidohydrolase
GYM62_13955	COG0497	DNA recombination
GYM62_13990	COG0037	tRNA processing
GYM62_14000	COG0039	L-malate dehydrogenase activity
GYM62_14010	COG0668	transmembrane transport
GYM62_14045	COG1045	serine acetyltransferase
GYM62_14060	COG0148	phosphopyruvate hydratase activity
GYM62_14065	COG0505	Belongs to the CarA family
GYM62_14070	COG0203	ribosomal protein L17
GYM62_14075	COG0202	RNA polymerase activity
GYM62_14080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GYM62_14085	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GYM62_14090	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GYM62_14095	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GYM62_14100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GYM62_14110	COG0201	protein transport
GYM62_14115	COG0200	Binds to the 23S rRNA
GYM62_14120	COG1841	ribosomal large subunit assembly
GYM62_14125	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GYM62_14135	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GYM62_14140	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GYM62_14145	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GYM62_14150	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GYM62_14155	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GYM62_14160	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GYM62_14165	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GYM62_14170	COG0255	Belongs to the universal ribosomal protein uL29 family
GYM62_14175	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GYM62_14180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GYM62_14185	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GYM62_14190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GYM62_14195	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GYM62_14200	COG0089	rRNA binding
GYM62_14205	COG0088	Forms part of the polypeptide exit tunnel
GYM62_14210	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GYM62_14215	COG0051	transcription antitermination factor activity, RNA binding
GYM62_14220	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GYM62_14225	COG0049	tRNA binding
GYM62_14230	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GYM62_14240	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GYM62_14245	COG0085	RNA polymerase activity
GYM62_14250	COG0222	ribosome binding
GYM62_14255	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GYM62_14260	COG0081	regulation of translation
GYM62_14265	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GYM62_14310	COG4770	biotin carboxylase activity
GYM62_14315	COG0528	UMP kinase activity
GYM62_14320	COG0233	cytoplasmic translational termination
GYM62_14330	COG1629	transport
GYM62_14335	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GYM62_14370	COG1373	ATPase (AAA superfamily
GYM62_14375	COG0328	RNA-DNA hybrid ribonuclease activity
GYM62_14380	COG2095	MarC family integral membrane protein
GYM62_14385	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GYM62_14390	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GYM62_14395	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GYM62_14400	COG1629	transport
GYM62_14420	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GYM62_14430	COG1472	Belongs to the glycosyl hydrolase 3 family
GYM62_14440	COG0438	transferase activity, transferring glycosyl groups
GYM62_14450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GYM62_14460	COG4993	Dehydrogenase
GYM62_14480	COG4585	Histidine kinase
GYM62_14485	COG1960	acyl-CoA dehydrogenase activity
GYM62_14495	COG4974	Belongs to the 'phage' integrase family
GYM62_14500	COG0242	peptide deformylase activity
GYM62_14535	COG0488	(ABC) transporter
GYM62_14555	COG2197	response regulator
GYM62_14570	COG1054	Belongs to the UPF0176 family
GYM62_14595	COG0284	orotidine-5'-phosphate decarboxylase activity
GYM62_14610	COG0463	Glycosyl transferase, family 2
GYM62_14630	COG4974	Belongs to the 'phage' integrase family
GYM62_14635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GYM62_14645	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GYM62_14655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYM62_14665	COG3720	iron ion transport
GYM62_14680	COG0791	NLP P60 protein
GYM62_14695	COG0823	Involved in the tonB-independent uptake of proteins
GYM62_14695	COG1506	peptidase
GYM62_14700	COG1181	Belongs to the D-alanine--D-alanine ligase family
GYM62_14705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GYM62_14720	COG1960	acyl-CoA dehydrogenase activity
GYM62_14730	COG0657	acetylesterase activity
GYM62_14730	COG2755	lipolytic protein G-D-S-L family
GYM62_14735	COG3548	integral membrane protein
GYM62_14750	COG1525	nuclease
GYM62_14755	COG0330	HflC and HflK could
GYM62_14760	COG0330	HflC and HflK could
GYM62_14785	COG4771	TonB-dependent receptor
GYM62_14895	COG0464	growth
GYM62_14905	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GYM62_14925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GYM62_14960	COG0739	heme binding
GYM62_15060	COG2197	response regulator
GYM62_15080	COG1192	Involved in chromosome partitioning
GYM62_15100	COG1752	Esterase of the alpha-beta hydrolase superfamily
GYM62_15110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GYM62_15120	COG1309	transcriptional regulator
GYM62_15135	COG3384	dioxygenase
GYM62_15140	COG0702	epimerase
GYM62_15190	COG4974	Belongs to the 'phage' integrase family
GYM62_15225	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GYM62_15230	COG1160	GTP binding
GYM62_15245	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GYM62_15250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GYM62_15270	COG2801	Transposase and inactivated derivatives
GYM62_15280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GYM62_15305	COG0308	aminopeptidase N
GYM62_15310	COG0456	acetyltransferase
GYM62_15325	COG0295	cytidine deaminase activity
GYM62_15350	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GYM62_15355	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GYM62_15360	COG2807	transmembrane transport
GYM62_15365	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GYM62_15370	COG0475	glutathione-regulated potassium exporter activity
GYM62_15440	COG2826	transposase and inactivated derivatives, IS30 family
GYM62_15470	COG0247	lactate metabolic process
GYM62_15470	COG2181	nitrate reductase activity
GYM62_15475	COG0247	lactate metabolic process
GYM62_15475	COG2181	nitrate reductase activity
GYM62_15485	COG2885	chlorophyll binding
GYM62_15505	COG2852	Protein conserved in bacteria
GYM62_15520	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GYM62_15525	COG2226	methyltransferase
GYM62_15535	COG4221	oxidoreductase activity
GYM62_15545	COG0167	dihydroorotate dehydrogenase activity
GYM62_15550	COG1674	ftsk spoiiie
GYM62_15560	COG0512	Glutamine amidotransferase of anthranilate synthase
GYM62_15570	COG1610	YqeY-like protein
GYM62_15575	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GYM62_15580	COG0596	Alpha beta hydrolase
GYM62_15585	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GYM62_15595	COG1404	Belongs to the peptidase S8 family
GYM62_15605	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GYM62_15645	COG0228	four-way junction DNA binding
GYM62_15650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GYM62_15655	COG0336	Belongs to the RNA methyltransferase TrmD family
GYM62_15660	COG0335	large ribosomal subunit rRNA binding
GYM62_15665	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GYM62_15665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GYM62_15695	COG4206	TonB-dependent receptor
GYM62_15695	COG1629	transport
GYM62_15715	COG1131	(ABC) transporter
GYM62_15725	COG4977	sequence-specific DNA binding
GYM62_15725	COG1917	Cupin 2, conserved barrel domain protein
GYM62_15730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GYM62_15740	COG3938	Belongs to the proline racemase family
GYM62_15745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GYM62_15755	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GYM62_15760	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GYM62_15765	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GYM62_15770	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GYM62_15775	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GYM62_15780	COG0356	it plays a direct role in the translocation of protons across the membrane
GYM62_15805	COG0322	excinuclease ABC activity
GYM62_15825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GYM62_15850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GYM62_15865	COG1366	Belongs to the anti-sigma-factor antagonist family
GYM62_15875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GYM62_15880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GYM62_15890	COG1132	(ABC) transporter
GYM62_15900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GYM62_15915	COG1862	Preprotein translocase
GYM62_15945	COG0450	alkyl hydroperoxide reductase
GYM62_15950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GYM62_15975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GYM62_15985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GYM62_16005	COG3118	belongs to the thioredoxin family
GYM62_16015	COG1187	pseudouridine synthase activity
GYM62_16020	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GYM62_16045	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GYM62_16050	COG1966	Carbon starvation protein
GYM62_16070	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GYM62_16070	COG5180	pathogenesis
GYM62_16075	COG0195	Participates in both transcription termination and antitermination
GYM62_16075	COG2251	uridine kinase activity
GYM62_16080	COG0779	Required for maturation of 30S ribosomal subunits
GYM62_16085	COG1077	Cell shape determining protein MreB Mrl
GYM62_16100	COG0768	penicillin binding
GYM62_16105	COG0772	Belongs to the SEDS family
GYM62_16125	COG1381	Involved in DNA repair and RecF pathway recombination
GYM62_16130	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GYM62_16155	COG0564	pseudouridine synthase activity
GYM62_16160	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GYM62_16170	COG0556	nucleotide-excision repair
GYM62_16185	COG2610	gluconate transmembrane transporter activity
GYM62_16195	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GYM62_16205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GYM62_16215	COG0596	Alpha beta hydrolase
GYM62_16230	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GYM62_16235	COG0739	heme binding
GYM62_16245	COG1187	pseudouridine synthase activity
GYM62_16250	COG2885	chlorophyll binding
GYM62_16280	COG2885	chlorophyll binding
GYM62_16300	COG0657	acetylesterase activity
GYM62_16310	COG1595	DNA-templated transcription, initiation
GYM62_16325	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GYM62_16330	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GYM62_16340	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GYM62_16360	COG0668	transmembrane transport
GYM62_16370	COG3424	synthase
GYM62_16380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GYM62_16405	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GYM62_16410	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GYM62_16455	COG0714	Associated with various cellular activities
GYM62_16460	COG1187	pseudouridine synthase activity
GYM62_16480	COG1473	amidohydrolase
GYM62_16500	COG0702	epimerase
GYM62_16505	COG4771	TonB-dependent receptor
GYM62_16540	COG1132	(ABC) transporter
GYM62_16560	COG4591	ABC-type transport system involved in lipoprotein release permease component
GYM62_16565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GYM62_16575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GYM62_16585	COG0572	uridine kinase
GYM62_16590	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GYM62_16615	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GYM62_16620	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GYM62_16625	COG0363	glucosamine-6-phosphate deaminase activity
GYM62_16630	COG1064	alcohol dehydrogenase
GYM62_16660	COG2801	Transposase and inactivated derivatives
GYM62_16680	COG2255	four-way junction helicase activity
GYM62_16685	COG1477	protein flavinylation
GYM62_16700	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GYM62_16705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GYM62_16735	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GYM62_16740	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GYM62_16745	COG0698	ribose 5-phosphate isomerase
GYM62_16750	COG0805	protein transport
GYM62_16755	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GYM62_16770	COG3344	reverse transcriptase
GYM62_16780	COG0679	Auxin Efflux Carrier
GYM62_16785	COG0483	inositol monophosphate 1-phosphatase activity
GYM62_16790	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GYM62_16795	COG2154	pterin-4-alpha-carbinolamine dehydratase
GYM62_16835	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GYM62_16845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GYM62_16860	COG0519	Catalyzes the synthesis of GMP from XMP
GYM62_16870	COG0788	formyltetrahydrofolate deformylase activity
GYM62_16875	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GYM62_16885	COG1809	phosphosulfolactate synthase activity
GYM62_16895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GYM62_16900	COG4464	protein tyrosine phosphatase activity
GYM62_16905	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GYM62_16910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GYM62_16915	COG5002	protein histidine kinase activity
GYM62_16960	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GYM62_16965	COG0598	Magnesium transport protein CorA
GYM62_16970	COG0157	Belongs to the NadC ModD family
GYM62_16980	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GYM62_17015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GYM62_17015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GYM62_17020	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GYM62_17025	COG2801	Transposase and inactivated derivatives
GYM62_17050	COG0076	glutamate decarboxylase activity
GYM62_17055	COG0823	Involved in the tonB-independent uptake of proteins
GYM62_17055	COG1506	peptidase
GYM62_17080	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GYM62_17100	COG1595	DNA-templated transcription, initiation
GYM62_17125	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GYM62_17170	COG2826	transposase and inactivated derivatives, IS30 family
GYM62_17185	COG2860	membrane
GYM62_17190	COG2226	methyltransferase
GYM62_17205	COG0156	8-amino-7-oxononanoate synthase activity
GYM62_17215	COG0415	Belongs to the DNA photolyase family
GYM62_17235	COG0432	Pfam Uncharacterised protein family UPF0047
GYM62_17255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GYM62_17255	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GYM62_17265	COG4585	Histidine kinase
GYM62_17275	COG1473	amidohydrolase
GYM62_17285	COG0653	protein targeting
GYM62_17290	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GYM62_17295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GYM62_17310	COG0668	transmembrane transport
GYM62_17340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GYM62_17360	COG2197	response regulator
GYM62_17365	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GYM62_17385	COG2801	Transposase and inactivated derivatives
GYM62_17415	COG1040	competence protein
GYM62_17430	COG0708	Exodeoxyribonuclease III
GYM62_17440	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GYM62_17445	COG0445	tRNA wobble uridine modification
GYM62_17450	COG2226	methyltransferase
GYM62_17460	COG1022	Amp-dependent synthetase and ligase
GYM62_17470	COG1024	Enoyl-CoA hydratase
GYM62_17470	COG1250	3-hydroxyacyl-CoA dehydrogenase
GYM62_17480	COG0183	Belongs to the thiolase family
GYM62_17485	COG1960	acyl-CoA dehydrogenase activity
GYM62_17510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GYM62_17510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GYM62_17515	COG1956	GAF domain-containing protein
GYM62_17530	COG0662	Cupin 2, conserved barrel domain protein
GYM62_17535	COG3844	kynureninase activity
GYM62_17540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GYM62_17560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GYM62_17570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GYM62_17600	COG0154	amidase activity
GYM62_17615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GYM62_17620	COG0367	asparagine synthase
GYM62_17665	COG1073	alpha beta
GYM62_17665	COG2226	methyltransferase
GYM62_17685	COG3023	N-Acetylmuramoyl-L-alanine amidase
GYM62_17730	COG1629	transport
GYM62_17730	COG4206	TonB-dependent receptor
GYM62_17765	COG0653	protein targeting
GYM62_17885	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GYM62_17910	COG3956	TIGRFAM MazG family protein
GYM62_17920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GYM62_17925	COG1104	cysteine desulfurase activity
GYM62_17985	COG0423	glycine-tRNA ligase activity
GYM62_18010	COG0423	glycine-tRNA ligase activity
GYM62_18035	COG0149	triose-phosphate isomerase activity
GYM62_18040	COG2264	protein methyltransferase activity
GYM62_18045	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GYM62_18045	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GYM62_18050	COG1137	ATPase activity
GYM62_18065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GYM62_18075	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GYM62_18085	COG3622	Belongs to the hyi family
GYM62_18090	COG0673	inositol 2-dehydrogenase activity
GYM62_18095	COG0515	serine threonine protein kinase
GYM62_18095	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GYM62_18110	COG0626	cystathionine gamma-synthase activity
GYM62_18120	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GYM62_18130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GYM62_18140	COG0297	glycogen (starch) synthase activity
GYM62_18145	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GYM62_18150	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GYM62_18165	COG1960	acyl-CoA dehydrogenase activity
GYM62_18170	COG1917	Cupin 2, conserved barrel domain protein
GYM62_18170	COG4977	sequence-specific DNA binding
GYM62_18175	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GYM62_18195	COG1611	Belongs to the LOG family
GYM62_18205	COG0516	GMP reductase activity
GYM62_18205	COG0517	IMP dehydrogenase activity
GYM62_18215	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GYM62_18225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GYM62_18230	COG0673	inositol 2-dehydrogenase activity
GYM62_18235	COG2197	response regulator
GYM62_18240	COG4585	Histidine kinase
GYM62_18260	COG1138	Cytochrome C-type biogenesis protein
GYM62_18285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GYM62_18295	COG0004	ammonium transporteR
GYM62_18320	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GYM62_18325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GYM62_18335	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GYM62_18340	COG0527	aspartate kinase activity
GYM62_18350	COG1764	response to oxidative stress
GYM62_18360	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GYM62_18380	COG4948	Mandelate Racemase Muconate Lactonizing
GYM62_18415	COG3046	protein related to deoxyribodipyrimidine photolyase
GYM62_18495	COG1764	response to oxidative stress
GYM62_18500	COG1846	Transcriptional regulator
GYM62_18505	COG3118	belongs to the thioredoxin family
GYM62_18510	COG0673	inositol 2-dehydrogenase activity
GYM62_18515	COG0583	DNA-binding transcription factor activity
GYM62_18520	COG3015	lipoprotein NlpE involved in copper resistance
GYM62_18560	COG4771	TonB-dependent receptor
GYM62_18565	COG1968	undecaprenyl-diphosphatase activity
GYM62_18585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GYM62_18590	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GYM62_18595	COG1845	cytochrome c oxidase, subunit III
GYM62_18615	COG1704	LemA family
GYM62_18630	COG0105	UTP biosynthetic process
GYM62_18635	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GYM62_18640	COG0545	Peptidyl-prolyl cis-trans isomerase
GYM62_18665	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GYM62_18670	COG1283	sodium-dependent phosphate transmembrane transporter activity
GYM62_18680	COG0590	tRNA wobble adenosine to inosine editing
GYM62_18725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GYM62_18750	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GYM62_18755	COG0217	transcriptional regulatory protein
GYM62_18760	COG1252	NADH dehydrogenase
GYM62_18775	COG0067	glutamate synthase
GYM62_18775	COG0070	glutamate synthase
GYM62_18775	COG0069	glutamate synthase activity
GYM62_18785	COG0629	single-stranded DNA binding
GYM62_18795	COG0776	regulation of translation
GYM62_18805	COG1530	ribonuclease E activity
GYM62_18820	COG3279	Response regulator of the LytR AlgR family
GYM62_18825	COG2972	Histidine kinase
GYM62_18835	COG4771	TonB-dependent receptor
GYM62_18850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GYM62_18865	COG1090	epimerase
GYM62_18870	COG0038	chloride channel
GYM62_18875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GYM62_18880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GYM62_18895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GYM62_18900	COG0596	Alpha beta hydrolase
GYM62_18905	COG2890	protein-(glutamine-N5) methyltransferase activity
GYM62_18915	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GYM62_18915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GYM62_18925	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
GYM62_18940	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GYM62_18945	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GYM62_18950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GYM62_18955	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GYM62_19035	COG0517	IMP dehydrogenase activity
GYM62_19040	COG4974	Belongs to the 'phage' integrase family
GYM62_19045	COG3344	reverse transcriptase
GYM62_19055	COG0583	DNA-binding transcription factor activity
GYM62_19060	COG0753	catalase activity
GYM62_19070	COG4974	Belongs to the 'phage' integrase family
GYM62_19090	COG0784	Response regulator, receiver
GYM62_19095	COG3279	Response regulator of the LytR AlgR family
GYM62_19105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GYM62_19110	COG0346	lactoylglutathione lyase activity
GYM62_19180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GYM62_19215	COG0084	hydrolase, TatD family'
GYM62_19225	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GYM62_19245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GYM62_19250	COG4946	Tricorn protease homolog
GYM62_19250	COG0793	Belongs to the peptidase S41A family
GYM62_19275	COG0793	Belongs to the peptidase S41A family
GYM62_19275	COG4946	Tricorn protease homolog
GYM62_19280	COG1028	Short-chain dehydrogenase reductase Sdr
GYM62_19315	COG3279	Response regulator of the LytR AlgR family
GYM62_19330	COG2205	protein histidine kinase activity
GYM62_19330	COG3292	Two component regulator propeller
GYM62_19330	COG0745	RESPONSE REGULATOR receiver
GYM62_19355	COG5002	protein histidine kinase activity
GYM62_19370	COG4191	Histidine kinase
GYM62_19420	COG2072	flavoprotein involved in K transport
GYM62_19425	COG3961	Belongs to the TPP enzyme family
GYM62_19435	COG3852	Histidine kinase
GYM62_19445	COG4946	Tricorn protease homolog
GYM62_19445	COG1506	peptidase
GYM62_19445	COG0823	Involved in the tonB-independent uptake of proteins
GYM62_19450	COG0531	amino acid
GYM62_19470	COG3119	arylsulfatase activity
GYM62_19510	COG0326	Molecular chaperone. Has ATPase activity
GYM62_19535	COG2801	Transposase and inactivated derivatives
GYM62_19540	COG1959	2 iron, 2 sulfur cluster binding
GYM62_19550	COG0175	sulfate reduction
GYM62_19555	COG0175	sulfate reduction
GYM62_19560	COG2895	sulfate adenylyltransferase (ATP) activity
GYM62_19565	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GYM62_19575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GYM62_19575	COG1648	precorrin-2 dehydrogenase activity
GYM62_19600	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GYM62_19605	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GYM62_19615	COG3387	PFAM Glycoside hydrolase 15-related
GYM62_19635	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GYM62_19640	COG0194	GDP metabolic process
GYM62_19650	COG1595	DNA-templated transcription, initiation
GYM62_19670	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GYM62_19675	COG0129	dihydroxy-acid dehydratase activity
GYM62_19680	COG1028	Short-chain dehydrogenase reductase Sdr
GYM62_19740	COG1523	belongs to the glycosyl hydrolase 13 family
GYM62_19770	COG3119	arylsulfatase activity
GYM62_19825	COG1595	DNA-templated transcription, initiation
GYM62_19850	COG4628	conserved protein (DUF2132)
GYM62_19865	COG0592	DNA-directed DNA polymerase activity
GYM62_19880	COG1131	(ABC) transporter
GYM62_19885	COG1028	Short-chain dehydrogenase reductase Sdr
GYM62_19890	COG1473	amidohydrolase
GYM62_19895	COG1473	amidohydrolase
GYM62_19900	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GYM62_19905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GYM62_19910	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GYM62_19915	COG1349	DNA-binding transcription factor activity
GYM62_19925	COG0564	pseudouridine synthase activity
GYM62_19935	COG0492	ferredoxin-NADP+ reductase activity
GYM62_19945	COG1902	pentaerythritol trinitrate reductase activity
GYM62_19950	COG1028	Short-chain dehydrogenase reductase Sdr
GYM62_19965	COG2001	Belongs to the MraZ family
GYM62_19970	COG0275	rRNA processing
GYM62_19980	COG0768	penicillin binding
GYM62_19985	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GYM62_19990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GYM62_19995	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GYM62_20000	COG0772	Belongs to the SEDS family
GYM62_20005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GYM62_20010	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GYM62_20025	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GYM62_20060	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GYM62_20075	COG0697	spore germination
GYM62_20080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GYM62_20100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GYM62_20105	COG0688	phosphatidylethanolamine metabolic process
GYM62_20125	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GYM62_20130	COG0612	Peptidase, M16
GYM62_20135	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GYM62_20140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GYM62_20150	COG1629	transport
GYM62_20225	COG0542	response to heat
GYM62_20235	COG0259	pyridoxamine-phosphate oxidase activity
GYM62_20250	COG0475	glutathione-regulated potassium exporter activity
GYM62_20250	COG0589	response to stress
GYM62_20265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GYM62_20350	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GYM62_20360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GYM62_20375	COG0561	phosphatase activity
GYM62_20400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GYM62_20410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GYM62_20425	COG1028	Short-chain dehydrogenase reductase Sdr
GYM62_20440	COG0460	homoserine dehydrogenase
GYM62_20440	COG0527	aspartate kinase activity
GYM62_20445	COG0083	homoserine kinase activity
GYM62_20450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GYM62_20455	COG3177	Filamentation induced by cAMP protein fic
GYM62_20490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GYM62_20500	COG2133	pyrroloquinoline quinone binding
GYM62_20510	COG0527	aspartate kinase activity
GYM62_20515	COG0673	inositol 2-dehydrogenase activity
GYM62_20525	COG3001	Fructosamine kinase
GYM62_20530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GYM62_20550	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GYM62_20560	COG0297	glycogen (starch) synthase activity
GYM62_20580	COG0513	Belongs to the DEAD box helicase family
GYM62_20590	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GYM62_20590	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GYM62_20600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GYM62_20600	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GYM62_20605	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GYM62_20610	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GYM62_20615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GYM62_20640	COG0142	geranyltranstransferase activity
GYM62_20645	COG0557	exoribonuclease II activity
GYM62_20660	COG0321	lipoyl(octanoyl) transferase activity
GYM62_20665	COG0792	nuclease activity
GYM62_20690	COG1215	transferase activity, transferring glycosyl groups
GYM62_20705	COG0693	protein deglycase activity
GYM62_20750	COG0793	Belongs to the peptidase S41A family
GYM62_20760	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GYM62_20765	COG0242	peptide deformylase activity
GYM62_20770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GYM62_20790	COG3279	Response regulator of the LytR AlgR family
GYM62_20795	COG2972	Histidine kinase
GYM62_20865	COG0673	inositol 2-dehydrogenase activity
GYM62_20870	COG2211	Major facilitator Superfamily
GYM62_20875	COG1082	Xylose isomerase domain protein TIM barrel