locus-tag	class	description
OM944_00030	COG3279	Response regulator of the LytR AlgR family
OM944_00080	COG1216	Glycosyl transferase, family 2
OM944_00080	COG1442	glycosyl transferase family 8
OM944_00085	COG1215	transferase activity, transferring glycosyl groups
OM944_00090	COG1132	(ABC) transporter
OM944_00095	COG0463	Glycosyl transferase, family 2
OM944_00155	COG4771	TonB-dependent receptor
OM944_00160	COG0702	epimerase
OM944_00170	COG2207	Transcriptional regulator
OM944_00175	COG0693	protein deglycase activity
OM944_00175	COG0753	catalase activity
OM944_00190	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_00200	COG1970	mechanosensitive ion channel activity
OM944_00210	COG0702	epimerase
OM944_00215	COG1629	transport
OM944_00255	COG1704	LemA family
OM944_00310	COG3279	Response regulator of the LytR AlgR family
OM944_00315	COG0745	RESPONSE REGULATOR receiver
OM944_00315	COG2972	Histidine kinase
OM944_00330	COG3279	Response regulator of the LytR AlgR family
OM944_00360	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OM944_00365	COG0667	Aldo Keto reductase
OM944_00375	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OM944_00380	COG0732	type I restriction modification DNA specificity domain
OM944_00385	COG5290	Psort location Cytoplasmic, score
OM944_00400	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OM944_00435	COG0464	growth
OM944_00485	COG1629	transport
OM944_00485	COG4206	TonB-dependent receptor
OM944_00515	COG3279	Response regulator of the LytR AlgR family
OM944_00560	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OM944_00565	COG4948	Mandelate Racemase Muconate Lactonizing
OM944_00570	COG2706	6-phosphogluconolactonase activity
OM944_00575	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OM944_00635	COG0671	phosphoesterase, PA-phosphatase related
OM944_00640	COG0408	coproporphyrinogen oxidase activity
OM944_00650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM944_00675	COG2151	metal-sulfur cluster biosynthetic enzyme
OM944_00680	COG2166	iron-sulfur cluster assembly
OM944_00685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OM944_00690	COG0719	Fe-S assembly protein
OM944_00695	COG0396	ATPase activity
OM944_00700	COG0719	Fe-S assembly protein
OM944_00705	COG1522	sequence-specific DNA binding
OM944_00715	COG1506	peptidase
OM944_00715	COG0823	Involved in the tonB-independent uptake of proteins
OM944_00720	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OM944_00765	COG2244	polysaccharide biosynthetic process
OM944_00790	COG1215	transferase activity, transferring glycosyl groups
OM944_00805	COG1215	transferase activity, transferring glycosyl groups
OM944_00810	COG1216	Glycosyl transferase, family 2
OM944_00820	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OM944_00855	COG1216	Glycosyl transferase, family 2
OM944_00855	COG1442	glycosyl transferase family 8
OM944_00865	COG0438	transferase activity, transferring glycosyl groups
OM944_00875	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
OM944_00895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM944_00900	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OM944_00925	COG1960	acyl-CoA dehydrogenase activity
OM944_00945	COG0673	inositol 2-dehydrogenase activity
OM944_00950	COG0577	efflux transmembrane transporter activity
OM944_00950	COG1136	(ABC) transporter
OM944_00970	COG1573	uracil-dna glycosylase
OM944_00990	COG4771	TonB-dependent receptor
OM944_01000	COG3119	arylsulfatase activity
OM944_01015	COG1595	DNA-templated transcription, initiation
OM944_01065	COG3279	Response regulator of the LytR AlgR family
OM944_01085	COG0071	Belongs to the small heat shock protein (HSP20) family
OM944_01095	COG0045	succinate-CoA ligase (ADP-forming) activity
OM944_01100	COG1136	(ABC) transporter
OM944_01105	COG0450	alkyl hydroperoxide reductase
OM944_01115	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OM944_01120	COG1335	isochorismatase
OM944_01145	COG1960	acyl-CoA dehydrogenase activity
OM944_01150	COG0318	PFAM AMP-dependent synthetase and ligase
OM944_01155	COG3119	arylsulfatase activity
OM944_01160	COG3119	arylsulfatase activity
OM944_01165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM944_01170	COG0110	maltose O-acetyltransferase activity
OM944_01175	COG1312	Catalyzes the dehydration of D-mannonate
OM944_01180	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_01185	COG1904	glucuronate isomerase
OM944_01190	COG1609	Transcriptional regulator
OM944_01200	COG4771	TonB-dependent receptor
OM944_01210	COG4771	TonB-dependent receptor
OM944_01215	COG0673	inositol 2-dehydrogenase activity
OM944_01225	COG0116	Belongs to the methyltransferase superfamily
OM944_01225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM944_01240	COG3279	Response regulator of the LytR AlgR family
OM944_01245	COG2972	Histidine kinase
OM944_01260	COG1984	allophanate hydrolase subunit 2
OM944_01265	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OM944_01285	COG3852	Histidine kinase
OM944_01290	COG0784	Response regulator, receiver
OM944_01295	COG4251	negative regulation of phosphorylation
OM944_01305	COG3237	CsbD-like
OM944_01320	COG2204	response regulator
OM944_01325	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OM944_01330	COG0513	Belongs to the DEAD box helicase family
OM944_01340	COG0156	8-amino-7-oxononanoate synthase activity
OM944_01345	COG4770	biotin carboxylase activity
OM944_01355	COG0424	maF-like protein
OM944_01380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OM944_01410	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OM944_01435	COG0450	alkyl hydroperoxide reductase
OM944_01470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OM944_01505	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OM944_01510	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OM944_01515	COG0196	riboflavin kinase activity
OM944_01520	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OM944_01525	COG1968	undecaprenyl-diphosphatase activity
OM944_01535	COG2177	Part of the ABC transporter FtsEX involved in
OM944_01555	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM944_01565	COG0288	reversible hydration of carbon dioxide
OM944_01570	COG0659	secondary active sulfate transmembrane transporter activity
OM944_01575	COG0165	Argininosuccinate lyase
OM944_01585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OM944_01595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OM944_01600	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OM944_01605	COG0137	argininosuccinate synthase activity
OM944_01615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OM944_01655	COG1063	alcohol dehydrogenase
OM944_01680	COG1643	Atp-dependent helicase
OM944_01695	COG3119	arylsulfatase activity
OM944_01710	COG4771	TonB-dependent receptor
OM944_01725	COG0745	RESPONSE REGULATOR receiver
OM944_01745	COG3408	Glycogen debranching enzyme
OM944_01745	COG3119	arylsulfatase activity
OM944_01750	COG0469	pyruvate kinase activity
OM944_01770	COG1011	Hydrolase
OM944_01780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM944_01800	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OM944_01805	COG0489	protein tyrosine kinase activity
OM944_01810	COG0358	DNA primase activity
OM944_01815	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OM944_01815	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OM944_01825	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OM944_01830	COG2205	protein histidine kinase activity
OM944_01850	COG0205	6-phosphofructokinase activity
OM944_01855	COG1803	Methylglyoxal synthase
OM944_01860	COG1770	oligopeptidase
OM944_01865	COG1970	mechanosensitive ion channel activity
OM944_01880	COG1595	DNA-templated transcription, initiation
OM944_01905	COG0446	pyridine nucleotide-disulphide oxidoreductase
OM944_01920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM944_01930	COG0730	response to heat
OM944_01965	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM944_01970	COG0488	(ABC) transporter
OM944_02000	COG0825	malonyl-CoA metabolic process
OM944_02005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM944_02010	COG1752	Esterase of the alpha-beta hydrolase superfamily
OM944_02020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OM944_02040	COG0187	DNA topoisomerase II activity
OM944_02045	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OM944_02050	COG3273	potassium ion transport
OM944_02050	COG0471	metal ion transport
OM944_02085	COG0673	inositol 2-dehydrogenase activity
OM944_02090	COG1917	Cupin 2, conserved barrel domain protein
OM944_02090	COG2207	Transcriptional regulator
OM944_02110	COG2010	Cytochrome c
OM944_02110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OM944_02115	COG2080	2 iron, 2 sulfur cluster binding
OM944_02135	COG0798	PFAM Bile acid sodium symporter
OM944_02145	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
OM944_02185	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OM944_02190	COG3959	Transketolase, thiamine diphosphate binding domain
OM944_02195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OM944_02200	COG0739	heme binding
OM944_02205	COG0179	Fumarylacetoacetate (FAA) hydrolase
OM944_02220	COG1619	proteins homologs of microcin C7 resistance protein MccF
OM944_02225	COG2027	D-alanyl-D-alanine carboxypeptidase
OM944_02230	COG2363	Small membrane protein
OM944_02255	COG0686	Belongs to the AlaDH PNT family
OM944_02265	COG0022	dehydrogenase e1 component
OM944_02280	COG2204	response regulator
OM944_02315	COG2326	polyphosphate kinase activity
OM944_02335	COG0439	Biotin carboxylase
OM944_02340	COG0511	ligase activity, forming carbon-carbon bonds
OM944_02345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OM944_02350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM944_02355	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OM944_02365	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OM944_02370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OM944_02375	COG2239	Acts as a magnesium transporter
OM944_02380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OM944_02385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM944_02400	COG1321	iron dependent repressor
OM944_02405	COG4771	TonB-dependent receptor
OM944_02420	COG2217	Heavy metal translocating P-type atpase
OM944_02435	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OM944_02440	COG4771	TonB-dependent receptor
OM944_02520	COG1428	Deoxynucleoside kinase
OM944_02525	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM944_02595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OM944_02600	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OM944_02605	COG3104	oligopeptide transport
OM944_02610	COG1309	transcriptional regulator
OM944_02615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OM944_02640	COG0123	including yeast histone deacetylase and acetoin utilization protein
OM944_02670	COG1115	amino acid carrier protein
OM944_02675	COG1929	Belongs to the glycerate kinase type-1 family
OM944_02705	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OM944_02715	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM944_02730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM944_02735	COG3250	beta-galactosidase activity
OM944_02750	COG0668	transmembrane transport
OM944_02765	COG3185	4-Hydroxyphenylpyruvate dioxygenase
OM944_02805	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OM944_02810	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OM944_02850	COG2267	carboxylic ester hydrolase activity
OM944_02855	COG0384	phenazine biosynthesis protein PhzF
OM944_02860	COG1090	epimerase
OM944_02875	COG1196	nuclear chromosome segregation
OM944_02905	COG4952	isomerase
OM944_02925	COG3254	rhamnose metabolic process
OM944_02930	COG2755	lipolytic protein G-D-S-L family
OM944_02955	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OM944_02965	COG3119	arylsulfatase activity
OM944_02980	COG4251	negative regulation of phosphorylation
OM944_03010	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM944_03030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OM944_03040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM944_03055	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OM944_03060	COG0732	type I restriction modification DNA specificity domain
OM944_03070	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OM944_03090	COG2423	ornithine cyclodeaminase activity
OM944_03095	COG4206	TonB-dependent receptor
OM944_03100	COG1960	acyl-CoA dehydrogenase activity
OM944_03125	COG0471	metal ion transport
OM944_03130	COG3275	phosphorelay sensor kinase activity
OM944_03135	COG3279	Response regulator of the LytR AlgR family
OM944_03140	COG2207	Transcriptional regulator
OM944_03155	COG0673	inositol 2-dehydrogenase activity
OM944_03160	COG4654	Cytochrome c, class I
OM944_03185	COG1678	Uncharacterized ACR, COG1678
OM944_03190	COG0259	pyridoxamine-phosphate oxidase activity
OM944_03200	COG0739	heme binding
OM944_03205	COG0492	ferredoxin-NADP+ reductase activity
OM944_03210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM944_03215	COG1185	polyribonucleotide nucleotidyltransferase activity
OM944_03220	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OM944_03255	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OM944_03260	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OM944_03265	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OM944_03270	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OM944_03285	COG4206	TonB-dependent receptor
OM944_03285	COG1629	transport
OM944_03290	COG0579	oxidoreductase
OM944_03295	COG0069	glutamate synthase activity
OM944_03310	COG2081	HI0933 family
OM944_03315	COG0433	COG0433 Predicted ATPase
OM944_03335	COG2171	N-acyltransferase activity
OM944_03350	COG0803	Belongs to the bacterial solute-binding protein 9 family
OM944_03355	COG1121	(ABC) transporter
OM944_03360	COG1321	iron dependent repressor
OM944_03360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OM944_03365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OM944_03375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OM944_03380	COG4974	Belongs to the 'phage' integrase family
OM944_03460	COG3177	Filamentation induced by cAMP protein fic
OM944_03485	COG1574	metal-dependent hydrolase with the TIM-barrel fold
OM944_03495	COG0784	Response regulator, receiver
OM944_03510	COG2205	protein histidine kinase activity
OM944_03520	COG1366	Belongs to the anti-sigma-factor antagonist family
OM944_03530	COG3279	Response regulator of the LytR AlgR family
OM944_03535	COG3275	phosphorelay sensor kinase activity
OM944_03560	COG1793	dna ligase
OM944_03580	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OM944_03635	COG0482	sulfurtransferase activity
OM944_03640	COG0564	pseudouridine synthase activity
OM944_03650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM944_03660	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OM944_03665	COG2086	electron transfer activity
OM944_03685	COG0604	alcohol dehydrogenase
OM944_03690	COG0305	Participates in initiation and elongation during chromosome replication
OM944_03695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OM944_03700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM944_03720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM944_03740	COG2234	aminopeptidase activity
OM944_03745	COG1528	Iron-storage protein
OM944_03755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM944_03760	COG0307	riboflavin synthase, alpha
OM944_03765	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OM944_03770	COG1607	acyl-coa hydrolase
OM944_03780	COG2814	Major facilitator Superfamily
OM944_03800	COG1621	beta-fructofuranosidase activity
OM944_03805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM944_03810	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OM944_03815	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OM944_03825	COG5492	domain, Protein
OM944_03845	COG2382	esterase
OM944_03880	COG0436	Aminotransferase
OM944_03885	COG0010	Belongs to the arginase family
OM944_03895	COG0018	arginyl-trna synthetase
OM944_03900	COG0386	Belongs to the glutathione peroxidase family
OM944_03905	COG1575	Belongs to the MenA family. Type 1 subfamily
OM944_03910	COG0589	response to stress
OM944_03920	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OM944_03925	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OM944_03930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM944_03935	COG0131	Imidazoleglycerol-phosphate dehydratase
OM944_03935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OM944_03945	COG0463	Glycosyl transferase, family 2
OM944_03950	COG0577	efflux transmembrane transporter activity
OM944_03955	COG3876	Protein conserved in bacteria
OM944_03960	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OM944_03970	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OM944_03975	COG0300	oxidoreductase activity
OM944_03980	COG1058	Belongs to the CinA family
OM944_03980	COG1546	Belongs to the CinA family
OM944_03985	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM944_03990	COG0784	Response regulator, receiver
OM944_03990	COG5002	protein histidine kinase activity
OM944_04010	COG1703	isobutyryl-CoA mutase activity
OM944_04010	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OM944_04010	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OM944_04015	COG0427	acetyl-CoA hydrolase
OM944_04020	COG2814	Major facilitator Superfamily
OM944_04025	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OM944_04025	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OM944_04030	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OM944_04045	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
OM944_04065	COG4206	TonB-dependent receptor
OM944_04070	COG2304	oxidoreductase activity
OM944_04085	COG0183	Belongs to the thiolase family
OM944_04095	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OM944_04105	COG1234	tRNA 3'-trailer cleavage
OM944_04110	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OM944_04115	COG0513	Belongs to the DEAD box helicase family
OM944_04120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OM944_04130	COG0758	DNA mediated transformation
OM944_04130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OM944_04145	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OM944_04150	COG0646	methionine synthase
OM944_04150	COG1410	methionine synthase
OM944_04155	COG0646	methionine synthase
OM944_04155	COG1410	methionine synthase
OM944_04165	COG0784	Response regulator, receiver
OM944_04165	COG2205	protein histidine kinase activity
OM944_04175	COG0393	Putative heavy-metal-binding
OM944_04200	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
OM944_04215	COG1388	LysM domain
OM944_04215	COG0791	NLP P60 protein
OM944_04235	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OM944_04245	COG1136	(ABC) transporter
OM944_04255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM944_04270	COG2814	Major facilitator Superfamily
OM944_04280	COG0534	Mate efflux family protein
OM944_04290	COG1522	sequence-specific DNA binding
OM944_04315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OM944_04355	COG0745	RESPONSE REGULATOR receiver
OM944_04365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OM944_04370	COG1228	amidohydrolase
OM944_04375	COG0791	NLP P60 protein
OM944_04395	COG4977	sequence-specific DNA binding
OM944_04410	COG0534	Mate efflux family protein
OM944_04415	COG0363	glucosamine-6-phosphate deaminase activity
OM944_04420	COG0534	Mate efflux family protein
OM944_04430	COG3483	tryptophan 2,3-dioxygenase activity
OM944_04435	COG1960	acyl-CoA dehydrogenase activity
OM944_04460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OM944_04470	COG1024	Enoyl-CoA hydratase
OM944_04470	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM944_04475	COG0784	Response regulator, receiver
OM944_04475	COG2205	protein histidine kinase activity
OM944_04500	COG2321	neutral zinc metallopeptidase
OM944_04505	COG2176	DNA-directed DNA polymerase activity
OM944_04525	COG1201	RNA secondary structure unwinding
OM944_04550	COG1914	H( )-stimulated, divalent metal cation uptake system
OM944_04590	COG0667	Aldo Keto reductase
OM944_04595	COG1288	antiporter activity
OM944_04610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OM944_04615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OM944_04630	COG0848	biopolymer transport protein
OM944_04635	COG0811	peptide transport
OM944_04670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OM944_04695	COG1012	belongs to the aldehyde dehydrogenase family
OM944_04705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OM944_04720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OM944_04725	COG1404	Belongs to the peptidase S8 family
OM944_04735	COG0135	phosphoribosylanthranilate isomerase activity
OM944_04740	COG0656	L-ascorbic acid biosynthetic process
OM944_04745	COG0702	epimerase
OM944_04755	COG0673	inositol 2-dehydrogenase activity
OM944_04785	COG2824	Alkylphosphonate utilization operon protein PhnA
OM944_04805	COG2329	Antibiotic biosynthesis monooxygenase
OM944_04830	COG3291	Pkd domain containing protein
OM944_04845	COG0561	phosphatase activity
OM944_04850	COG4771	TonB-dependent receptor
OM944_04860	COG2205	protein histidine kinase activity
OM944_04860	COG0745	RESPONSE REGULATOR receiver
OM944_04860	COG3292	Two component regulator propeller
OM944_04865	COG2115	Belongs to the xylose isomerase family
OM944_04880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM944_04885	COG1760	l-serine dehydratase
OM944_04915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OM944_04920	COG4895	conserved protein (DUF2196)
OM944_04925	COG4807	Protein conserved in bacteria
OM944_04950	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OM944_04960	COG1104	cysteine desulfurase activity
OM944_04985	COG0673	inositol 2-dehydrogenase activity
OM944_05010	COG3507	Belongs to the glycosyl hydrolase 43 family
OM944_05020	COG0596	Alpha beta hydrolase
OM944_05030	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OM944_05035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OM944_05040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OM944_05045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM944_05145	COG0529	Catalyzes the synthesis of activated sulfate
OM944_05150	COG0471	metal ion transport
OM944_05150	COG3273	potassium ion transport
OM944_05160	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
OM944_05180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM944_05190	COG0662	Cupin 2, conserved barrel domain protein
OM944_05190	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
OM944_05210	COG0489	protein tyrosine kinase activity
OM944_05220	COG0489	protein tyrosine kinase activity
OM944_05220	COG3206	protein involved in exopolysaccharide biosynthesis
OM944_05265	COG4771	TonB-dependent receptor
OM944_05275	COG1595	DNA-templated transcription, initiation
OM944_05280	COG0584	glycerophosphoryl diester phosphodiesterase
OM944_05295	COG1629	transport
OM944_05295	COG4206	TonB-dependent receptor
OM944_05310	COG1609	Transcriptional regulator
OM944_05310	COG2207	Transcriptional regulator
OM944_05385	COG1629	transport
OM944_05385	COG4206	TonB-dependent receptor
OM944_05425	COG0438	transferase activity, transferring glycosyl groups
OM944_05435	COG1215	transferase activity, transferring glycosyl groups
OM944_05445	COG0463	Glycosyl transferase, family 2
OM944_05445	COG1216	Glycosyl transferase, family 2
OM944_05465	COG1132	(ABC) transporter
OM944_05510	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OM944_05525	COG0463	Glycosyl transferase, family 2
OM944_05530	COG1216	Glycosyl transferase, family 2
OM944_05555	COG2153	protein acetylation
OM944_05560	COG0577	efflux transmembrane transporter activity
OM944_05565	COG0577	efflux transmembrane transporter activity
OM944_05570	COG0577	efflux transmembrane transporter activity
OM944_05580	COG0577	efflux transmembrane transporter activity
OM944_05585	COG0577	efflux transmembrane transporter activity
OM944_05610	COG1271	oxidase subunit
OM944_05615	COG3781	membrane
OM944_05625	COG0577	efflux transmembrane transporter activity
OM944_05635	COG2205	protein histidine kinase activity
OM944_05645	COG0702	epimerase
OM944_05650	COG4771	TonB-dependent receptor
OM944_05655	COG0577	efflux transmembrane transporter activity
OM944_05655	COG1136	(ABC) transporter
OM944_05660	COG0577	efflux transmembrane transporter activity
OM944_05665	COG0577	efflux transmembrane transporter activity
OM944_05665	COG1136	(ABC) transporter
OM944_05675	COG2204	response regulator
OM944_05680	COG4191	Histidine kinase
OM944_05705	COG0714	Associated with various cellular activities
OM944_05775	COG0667	Aldo Keto reductase
OM944_05780	COG0205	6-phosphofructokinase activity
OM944_05790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OM944_05795	COG0784	Response regulator, receiver
OM944_05810	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OM944_05810	COG0321	lipoyl(octanoyl) transferase activity
OM944_05820	COG0469	pyruvate kinase activity
OM944_05830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM944_05835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OM944_05840	COG0571	ribonuclease III activity
OM944_05845	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OM944_05845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM944_05850	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OM944_05855	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OM944_05880	COG0339	signal peptide processing
OM944_05885	COG0628	permease
OM944_05895	COG0784	Response regulator, receiver
OM944_05895	COG5002	protein histidine kinase activity
OM944_05905	COG2198	Histidine kinase
OM944_05905	COG2205	protein histidine kinase activity
OM944_05905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OM944_05905	COG0784	Response regulator, receiver
OM944_05915	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OM944_05925	COG0628	permease
OM944_05930	COG0012	GTP binding
OM944_05945	COG0488	(ABC) transporter
OM944_05965	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OM944_05980	COG2135	peptidase activity
OM944_05985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM944_06010	COG1940	carbohydrate kinase activity
OM944_06025	COG3119	arylsulfatase activity
OM944_06030	COG0445	tRNA wobble uridine modification
OM944_06045	COG4771	TonB-dependent receptor
OM944_06055	COG4771	TonB-dependent receptor
OM944_06070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM944_06080	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM944_06090	COG0577	efflux transmembrane transporter activity
OM944_06105	COG1663	tetraacyldisaccharide 4'-kinase activity
OM944_06110	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OM944_06125	COG0406	alpha-ribazole phosphatase activity
OM944_06140	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OM944_06155	COG0583	DNA-binding transcription factor activity
OM944_06160	COG2986	histidine ammonia-lyase
OM944_06165	COG1228	amidohydrolase
OM944_06170	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OM944_06190	COG3386	PFAM SMP-30 Gluconolaconase
OM944_06205	COG0277	FAD linked oxidase domain protein
OM944_06205	COG0247	lactate metabolic process
OM944_06235	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_06240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OM944_06250	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OM944_06255	COG0346	lactoylglutathione lyase activity
OM944_06260	COG0316	Belongs to the HesB IscA family
OM944_06265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OM944_06270	COG2045	Belongs to the ComB family
OM944_06280	COG3119	arylsulfatase activity
OM944_06290	COG2388	GCN5-related N-acetyl-transferase
OM944_06295	COG0346	lactoylglutathione lyase activity
OM944_06300	COG0513	Belongs to the DEAD box helicase family
OM944_06315	COG2133	pyrroloquinoline quinone binding
OM944_06330	COG3661	Belongs to the glycosyl hydrolase 67 family
OM944_06335	COG2514	catechol 2,3-dioxygenase activity
OM944_06340	COG2267	carboxylic ester hydrolase activity
OM944_06380	COG3620	sequence-specific DNA binding
OM944_06400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM944_06410	COG2183	response to ionizing radiation
OM944_06415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM944_06440	COG3757	hydrolase, family 25
OM944_06485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OM944_06525	COG3511	phospholipase C
OM944_06560	COG2116	formate transmembrane transporter activity
OM944_06570	COG2346	COG2346, Truncated hemoglobins
OM944_06580	COG0657	acetylesterase activity
OM944_06580	COG2755	lipolytic protein G-D-S-L family
OM944_06635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OM944_06640	COG0673	inositol 2-dehydrogenase activity
OM944_06645	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_06650	COG0179	Fumarylacetoacetate (FAA) hydrolase
OM944_06660	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_06665	COG0738	Major facilitator superfamily
OM944_06675	COG2755	lipolytic protein G-D-S-L family
OM944_06675	COG0657	acetylesterase activity
OM944_06690	COG1132	(ABC) transporter
OM944_06695	COG4974	Belongs to the 'phage' integrase family
OM944_06765	COG0596	Alpha beta hydrolase
OM944_06775	COG0739	heme binding
OM944_06795	COG5002	protein histidine kinase activity
OM944_06800	COG0745	RESPONSE REGULATOR receiver
OM944_06820	COG4206	TonB-dependent receptor
OM944_06820	COG1629	transport
OM944_06835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM944_06855	COG2308	Evidence 4 Homologs of previously reported genes of
OM944_06860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM944_06865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM944_06865	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM944_06875	COG0302	gtp cyclohydrolase
OM944_06890	COG2989	Protein conserved in bacteria
OM944_06900	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OM944_06905	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OM944_06910	COG3153	acetyltransferase
OM944_06910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM944_06915	COG1511	domain protein
OM944_06915	COG3264	Mechanosensitive ion channel
OM944_06930	COG0251	oxidation-reduction process
OM944_06950	COG1725	Transcriptional regulator
OM944_06960	COG1131	(ABC) transporter
OM944_07025	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
OM944_07030	COG4206	TonB-dependent receptor
OM944_07030	COG1629	transport
OM944_07045	COG1506	peptidase
OM944_07045	COG0823	Involved in the tonB-independent uptake of proteins
OM944_07050	COG0346	lactoylglutathione lyase activity
OM944_07060	COG4206	TonB-dependent receptor
OM944_07060	COG1629	transport
OM944_07090	COG1331	Highly conserved protein containing a thioredoxin domain
OM944_07095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OM944_07100	COG5505	Protein of unknown function (DUF819)
OM944_07125	COG0473	3-isopropylmalate dehydrogenase activity
OM944_07130	COG1024	Enoyl-CoA hydratase
OM944_07155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM944_07160	COG0154	amidase activity
OM944_07165	COG0741	lytic transglycosylase activity
OM944_07165	COG1388	LysM domain
OM944_07175	COG0280	phosphate acetyltransferase
OM944_07175	COG0281	malic enzyme
OM944_07180	COG0632	four-way junction helicase activity
OM944_07190	COG0509	glycine decarboxylation via glycine cleavage system
OM944_07210	COG1561	YicC-like family, N-terminal region
OM944_07220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM944_07225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM944_07230	COG1183	phosphatidylcholine synthase activity
OM944_07250	COG1216	Glycosyl transferase, family 2
OM944_07265	COG1739	Uncharacterized protein family UPF0029
OM944_07275	COG1757	Na H antiporter
OM944_07280	COG2072	flavoprotein involved in K transport
OM944_07315	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_07325	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OM944_07335	COG0799	negative regulation of ribosome biogenesis
OM944_07340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OM944_07355	COG1047	Peptidyl-prolyl cis-trans
OM944_07360	COG2204	response regulator
OM944_07380	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
OM944_07395	COG0626	cystathionine gamma-synthase activity
OM944_07455	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OM944_07565	COG3321	synthase
OM944_07565	COG0604	alcohol dehydrogenase
OM944_07570	COG3279	Response regulator of the LytR AlgR family
OM944_07575	COG2972	Histidine kinase
OM944_07580	COG1131	(ABC) transporter
OM944_07615	COG0464	growth
OM944_07655	COG0702	epimerase
OM944_07665	COG0004	ammonium transporteR
OM944_07675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OM944_07680	COG0477	Major facilitator Superfamily
OM944_07680	COG2814	Major facilitator Superfamily
OM944_07685	COG0488	(ABC) transporter
OM944_07695	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OM944_07705	COG1136	(ABC) transporter
OM944_07735	COG1999	signal sequence binding
OM944_07740	COG1981	membrane
OM944_07750	COG1703	isobutyryl-CoA mutase activity
OM944_07760	COG3119	arylsulfatase activity
OM944_07765	COG3119	arylsulfatase activity
OM944_07775	COG3119	arylsulfatase activity
OM944_07785	COG3119	arylsulfatase activity
OM944_07795	COG4948	Mandelate Racemase Muconate Lactonizing
OM944_07810	COG4771	TonB-dependent receptor
OM944_07820	COG1629	transport
OM944_07835	COG3408	Glycogen debranching enzyme
OM944_07835	COG3119	arylsulfatase activity
OM944_07865	COG4771	TonB-dependent receptor
OM944_07900	COG4774	siderophore transport
OM944_07945	COG4106	trans-aconitate 2-methyltransferase activity
OM944_07965	COG2267	carboxylic ester hydrolase activity
OM944_07970	COG0673	inositol 2-dehydrogenase activity
OM944_08000	COG0702	epimerase
OM944_08005	COG1629	transport
OM944_08015	COG3119	arylsulfatase activity
OM944_08025	COG0456	acetyltransferase
OM944_08090	COG3022	response to hydroperoxide
OM944_08135	COG0017	Asparaginyl-tRNA synthetase
OM944_08140	COG2814	Major facilitator Superfamily
OM944_08145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OM944_08145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OM944_08150	COG2270	Major facilitator Superfamily
OM944_08170	COG0811	peptide transport
OM944_08180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM944_08185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM944_08200	COG0673	inositol 2-dehydrogenase activity
OM944_08205	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_08215	COG0659	secondary active sulfate transmembrane transporter activity
OM944_08225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM944_08230	COG3264	Mechanosensitive ion channel
OM944_08230	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
OM944_08235	COG1278	Cold shock
OM944_08245	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_08250	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OM944_08255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OM944_08275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OM944_08280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM944_08295	COG4771	TonB-dependent receptor
OM944_08305	COG4771	TonB-dependent receptor
OM944_08315	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OM944_08320	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OM944_08325	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OM944_08325	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OM944_08365	COG0633	Ferredoxin
OM944_08370	COG0492	ferredoxin-NADP+ reductase activity
OM944_08380	COG1120	ATPase activity
OM944_08385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM944_08410	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OM944_08420	COG2721	sulfolactate sulfo-lyase activity
OM944_08455	COG0702	epimerase
OM944_08460	COG4771	TonB-dependent receptor
OM944_08470	COG2755	lipolytic protein G-D-S-L family
OM944_08475	COG2755	lipolytic protein G-D-S-L family
OM944_08495	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
OM944_08505	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OM944_08510	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_08520	COG1904	glucuronate isomerase
OM944_08525	COG0246	Mannitol dehydrogenase
OM944_08550	COG1418	mRNA catabolic process
OM944_08575	COG2003	Belongs to the UPF0758 family
OM944_08580	COG0268	Binds directly to 16S ribosomal RNA
OM944_08590	COG0436	Aminotransferase
OM944_08605	COG1408	metallophosphoesterase
OM944_08625	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OM944_08680	COG0488	(ABC) transporter
OM944_08695	COG3279	Response regulator of the LytR AlgR family
OM944_08700	COG3275	phosphorelay sensor kinase activity
OM944_08710	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OM944_08715	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OM944_08720	COG0577	efflux transmembrane transporter activity
OM944_08720	COG1136	(ABC) transporter
OM944_08725	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OM944_08735	COG0745	RESPONSE REGULATOR receiver
OM944_08740	COG5002	protein histidine kinase activity
OM944_08745	COG0564	pseudouridine synthase activity
OM944_08750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OM944_08755	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OM944_08760	COG0052	Belongs to the universal ribosomal protein uS2 family
OM944_08765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OM944_08770	COG0006	proline dipeptidase activity
OM944_08775	COG0612	Peptidase, M16
OM944_08785	COG3103	Sh3 type 3 domain protein
OM944_08785	COG0791	NLP P60 protein
OM944_08785	COG1388	LysM domain
OM944_08800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OM944_08825	COG2801	Transposase and inactivated derivatives
OM944_08830	COG3177	Filamentation induced by cAMP protein fic
OM944_08840	COG0252	asparaginase activity
OM944_08845	COG0084	hydrolase, TatD family'
OM944_08850	COG1215	transferase activity, transferring glycosyl groups
OM944_08870	COG1215	transferase activity, transferring glycosyl groups
OM944_08875	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OM944_08905	COG3457	Alanine racemase
OM944_08925	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OM944_08930	COG1053	succinate dehydrogenase
OM944_08945	COG3011	Protein conserved in bacteria
OM944_08950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OM944_08960	COG3655	Transcriptional regulator
OM944_08970	COG0616	signal peptide processing
OM944_08980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OM944_08990	COG0126	phosphoglycerate kinase activity
OM944_08995	COG0009	L-threonylcarbamoyladenylate synthase
OM944_09020	COG0514	ATP-dependent DNA helicase (RecQ)
OM944_09030	COG2333	competence protein COMEC
OM944_09030	COG0658	competence protein
OM944_09040	COG2153	protein acetylation
OM944_09075	COG4181	ATPase activity
OM944_09120	COG0733	neurotransmitter:sodium symporter activity
OM944_09135	COG0181	hydroxymethylbilane synthase activity
OM944_09160	COG0254	rRNA binding
OM944_09170	COG1132	(ABC) transporter
OM944_09180	COG0606	chelatase, subunit chli
OM944_09190	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OM944_09225	COG0101	tRNA pseudouridine synthase activity
OM944_09230	COG1132	(ABC) transporter
OM944_09250	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OM944_09255	COG3217	Mosc domain protein beta barrel domain protein
OM944_09255	COG0633	Ferredoxin
OM944_09260	COG0443	Heat shock 70 kDa protein
OM944_09280	COG0004	ammonium transporteR
OM944_09285	COG0113	porphobilinogen synthase activity
OM944_09290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OM944_09295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OM944_09305	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OM944_09310	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OM944_09320	COG0552	protein localization to endoplasmic reticulum
OM944_09350	COG2226	methyltransferase
OM944_09355	COG1215	transferase activity, transferring glycosyl groups
OM944_09360	COG0463	Glycosyl transferase, family 2
OM944_09375	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OM944_09405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OM944_09420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OM944_09425	COG0248	Ppx GppA phosphatase
OM944_09445	COG0673	inositol 2-dehydrogenase activity
OM944_09475	COG0066	3-isopropylmalate dehydratase activity
OM944_09480	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OM944_09485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OM944_09490	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OM944_09500	COG0028	Belongs to the TPP enzyme family
OM944_09505	COG0129	dihydroxy-acid dehydratase activity
OM944_09510	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OM944_09525	COG0343	queuine tRNA-ribosyltransferase activity
OM944_09535	COG1595	DNA-templated transcription, initiation
OM944_09540	COG0357	Ribosomal RNA small subunit methyltransferase G
OM944_09550	COG3118	belongs to the thioredoxin family
OM944_09555	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
OM944_09560	COG0709	Synthesizes selenophosphate from selenide and ATP
OM944_09575	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OM944_09580	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OM944_09590	COG1805	sodium ion transport
OM944_09600	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OM944_09605	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OM944_09610	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OM944_09625	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OM944_09630	COG3852	Histidine kinase
OM944_09635	COG0783	Belongs to the Dps family
OM944_09640	COG1668	transmembrane transport
OM944_09645	COG4152	abc transporter atp-binding protein
OM944_09655	COG0484	heat shock protein binding
OM944_09660	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OM944_09665	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OM944_09670	COG0563	adenylate kinase activity
OM944_09675	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OM944_09685	COG2885	chlorophyll binding
OM944_09690	COG2885	chlorophyll binding
OM944_09695	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OM944_09725	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OM944_09735	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OM944_09735	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OM944_09745	COG0513	Belongs to the DEAD box helicase family
OM944_09765	COG0438	transferase activity, transferring glycosyl groups
OM944_09780	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OM944_09790	COG1162	GTPase activity
OM944_09800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OM944_09805	COG3001	Fructosamine kinase
OM944_09810	COG0673	inositol 2-dehydrogenase activity
OM944_09815	COG0527	aspartate kinase activity
OM944_09820	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
OM944_09825	COG2133	pyrroloquinoline quinone binding
OM944_09830	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OM944_09850	COG3177	Filamentation induced by cAMP protein fic
OM944_09860	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OM944_09865	COG0083	homoserine kinase activity
OM944_09870	COG0527	aspartate kinase activity
OM944_09870	COG0460	homoserine dehydrogenase
OM944_09890	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_09910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM944_09920	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OM944_09945	COG0561	phosphatase activity
OM944_09960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OM944_09970	COG1574	metal-dependent hydrolase with the TIM-barrel fold
OM944_09990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM944_10000	COG3040	lipid binding
OM944_10020	COG4206	TonB-dependent receptor
OM944_10020	COG1629	transport
OM944_10025	COG0823	Involved in the tonB-independent uptake of proteins
OM944_10025	COG1506	peptidase
OM944_10045	COG0542	response to heat
OM944_10095	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM944_10110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OM944_10115	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OM944_10120	COG0612	Peptidase, M16
OM944_10125	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OM944_10150	COG0688	phosphatidylethanolamine metabolic process
OM944_10155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OM944_10175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM944_10180	COG1373	ATPase (AAA superfamily
OM944_10185	COG0697	spore germination
OM944_10205	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OM944_10220	COG4221	oxidoreductase activity
OM944_10230	COG2226	methyltransferase
OM944_10235	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OM944_10260	COG0328	RNA-DNA hybrid ribonuclease activity
OM944_10265	COG2095	MarC family integral membrane protein
OM944_10270	COG1943	Transposase
OM944_10275	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OM944_10280	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OM944_10290	COG4974	Belongs to the 'phage' integrase family
OM944_10330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OM944_10335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OM944_10340	COG0772	Belongs to the SEDS family
OM944_10345	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OM944_10350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM944_10355	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OM944_10360	COG0768	penicillin binding
OM944_10370	COG0275	rRNA processing
OM944_10375	COG2001	Belongs to the MraZ family
OM944_10380	COG0823	Involved in the tonB-independent uptake of proteins
OM944_10385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM944_10385	COG1648	precorrin-2 dehydrogenase activity
OM944_10395	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM944_10405	COG0175	sulfate reduction
OM944_10410	COG0175	sulfate reduction
OM944_10420	COG1959	2 iron, 2 sulfur cluster binding
OM944_10435	COG0326	Molecular chaperone. Has ATPase activity
OM944_10455	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OM944_10475	COG1960	acyl-CoA dehydrogenase activity
OM944_10485	COG0657	acetylesterase activity
OM944_10485	COG2755	lipolytic protein G-D-S-L family
OM944_10490	COG3119	arylsulfatase activity
OM944_10495	COG0791	NLP P60 protein
OM944_10505	COG1181	Belongs to the D-alanine--D-alanine ligase family
OM944_10510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OM944_10515	COG0475	glutathione-regulated potassium exporter activity
OM944_10540	COG1569	PIN domain
OM944_10545	COG3620	sequence-specific DNA binding
OM944_10555	COG0587	DNA-directed DNA polymerase activity
OM944_10560	COG0492	ferredoxin-NADP+ reductase activity
OM944_10570	COG1902	pentaerythritol trinitrate reductase activity
OM944_10575	COG3682	Transcriptional regulator
OM944_10600	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OM944_10605	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OM944_10610	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OM944_10615	COG1960	acyl-CoA dehydrogenase activity
OM944_10635	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM944_10665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OM944_10670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM944_10695	COG4771	TonB-dependent receptor
OM944_10740	COG1476	TRANSCRIPTIONal
OM944_10750	COG2003	Belongs to the UPF0758 family
OM944_10755	COG1002	Type II restriction enzyme, methylase subunits
OM944_10770	COG1061	Type III restriction enzyme res subunit
OM944_10775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OM944_10840	COG0739	heme binding
OM944_10840	COG0741	lytic transglycosylase activity
OM944_10840	COG1196	nuclear chromosome segregation
OM944_10940	COG2197	response regulator
OM944_10960	COG4581	dead DEAH box helicase
OM944_10980	COG2801	Transposase and inactivated derivatives
OM944_11015	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OM944_11020	COG1160	GTP binding
OM944_11035	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OM944_11040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OM944_11055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OM944_11080	COG0800	Aldolase
OM944_11115	COG0295	cytidine deaminase activity
OM944_11125	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OM944_11130	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
OM944_11135	COG2807	transmembrane transport
OM944_11140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OM944_11165	COG1595	DNA-templated transcription, initiation
OM944_11175	COG0247	lactate metabolic process
OM944_11175	COG2181	nitrate reductase activity
OM944_11180	COG0247	lactate metabolic process
OM944_11180	COG2181	nitrate reductase activity
OM944_11190	COG2885	chlorophyll binding
OM944_11210	COG1138	Cytochrome C-type biogenesis protein
OM944_11220	COG1137	ATPase activity
OM944_11225	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OM944_11225	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OM944_11235	COG2264	protein methyltransferase activity
OM944_11240	COG0149	triose-phosphate isomerase activity
OM944_11245	COG2137	regulation of response to DNA damage stimulus
OM944_11260	COG0423	glycine-tRNA ligase activity
OM944_11275	COG0673	inositol 2-dehydrogenase activity
OM944_11280	COG2197	response regulator
OM944_11305	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OM944_11315	COG0572	uridine kinase
OM944_11320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OM944_11335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OM944_11340	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM944_11345	COG0363	glucosamine-6-phosphate deaminase activity
OM944_11350	COG2255	four-way junction helicase activity
OM944_11355	COG1477	protein flavinylation
OM944_11370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM944_11375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OM944_11390	COG2176	DNA-directed DNA polymerase activity
OM944_11390	COG5002	protein histidine kinase activity
OM944_11415	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
OM944_11420	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OM944_11425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM944_11430	COG3844	kynureninase activity
OM944_11435	COG0662	Cupin 2, conserved barrel domain protein
OM944_11460	COG2890	protein-(glutamine-N5) methyltransferase activity
OM944_11470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OM944_11470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM944_11475	COG0516	GMP reductase activity
OM944_11475	COG0517	IMP dehydrogenase activity
OM944_11485	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OM944_11495	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OM944_11500	COG1472	Belongs to the glycosyl hydrolase 3 family
OM944_11510	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OM944_11530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OM944_11535	COG0488	(ABC) transporter
OM944_11555	COG3119	arylsulfatase activity
OM944_11570	COG0438	transferase activity, transferring glycosyl groups
OM944_11580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM944_11585	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM944_11585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM944_11595	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OM944_11605	COG3622	Belongs to the hyi family
OM944_11610	COG0673	inositol 2-dehydrogenase activity
OM944_11615	COG0515	serine threonine protein kinase
OM944_11615	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM944_11630	COG1629	transport
OM944_11650	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OM944_11660	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OM944_11670	COG0297	glycogen (starch) synthase activity
OM944_11675	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OM944_11680	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OM944_11695	COG1960	acyl-CoA dehydrogenase activity
OM944_11705	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OM944_11725	COG1611	Belongs to the LOG family
OM944_11740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OM944_11750	COG3279	Response regulator of the LytR AlgR family
OM944_11755	COG0745	RESPONSE REGULATOR receiver
OM944_11770	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OM944_11775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OM944_11780	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OM944_11785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OM944_11790	COG3177	Filamentation induced by cAMP protein fic
OM944_11805	COG2234	aminopeptidase activity
OM944_11830	COG3046	protein related to deoxyribodipyrimidine photolyase
OM944_11855	COG0019	diaminopimelate decarboxylase activity
OM944_11870	COG4948	Mandelate Racemase Muconate Lactonizing
OM944_11885	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
OM944_11890	COG1764	response to oxidative stress
OM944_11900	COG0438	transferase activity, transferring glycosyl groups
OM944_11910	COG4804	nuclease activity
OM944_11990	COG3852	Histidine kinase
OM944_12005	COG0405	Gamma-glutamyltransferase
OM944_12015	COG1566	PFAM secretion protein HlyD family protein
OM944_12025	COG2217	Heavy metal translocating P-type atpase
OM944_12035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OM944_12050	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
OM944_12070	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OM944_12080	COG0084	hydrolase, TatD family'
OM944_12105	COG3250	beta-galactosidase activity
OM944_12110	COG4804	nuclease activity
OM944_12125	COG3507	Belongs to the glycosyl hydrolase 43 family
OM944_12145	COG5564	TIM-barrel signal transduction protein
OM944_12150	COG3119	arylsulfatase activity
OM944_12155	COG4585	Histidine kinase
OM944_12160	COG2197	response regulator
OM944_12170	COG3852	Histidine kinase
OM944_12180	COG0784	Response regulator, receiver
OM944_12180	COG4191	Histidine kinase
OM944_12195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OM944_12200	COG3119	arylsulfatase activity
OM944_12260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM944_12260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM944_12270	COG2272	Belongs to the type-B carboxylesterase lipase family
OM944_12290	COG2972	Histidine kinase
OM944_12310	COG1530	ribonuclease E activity
OM944_12320	COG0776	regulation of translation
OM944_12330	COG0629	single-stranded DNA binding
OM944_12335	COG4535	Mg2 and Co2 transporter CorC
OM944_12340	COG0067	glutamate synthase
OM944_12340	COG0070	glutamate synthase
OM944_12340	COG0069	glutamate synthase activity
OM944_12355	COG1252	NADH dehydrogenase
OM944_12360	COG0217	transcriptional regulatory protein
OM944_12365	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
OM944_12385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM944_12415	COG0590	tRNA wobble adenosine to inosine editing
OM944_12425	COG1283	sodium-dependent phosphate transmembrane transporter activity
OM944_12430	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OM944_12445	COG0545	Peptidyl-prolyl cis-trans isomerase
OM944_12450	COG0545	Peptidyl-prolyl cis-trans isomerase
OM944_12455	COG0545	Peptidyl-prolyl cis-trans isomerase
OM944_12460	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OM944_12475	COG0105	UTP biosynthetic process
OM944_12485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM944_12490	COG2146	nitrite reductase [NAD(P)H] activity
OM944_12490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM944_12505	COG2197	response regulator
OM944_12510	COG2223	nitrite transmembrane transporter activity
OM944_12515	COG0243	molybdopterin cofactor binding
OM944_12520	COG1773	rubredoxin
OM944_12535	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OM944_12540	COG0315	cyclic pyranopterin monophosphate synthase activity
OM944_12550	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OM944_12560	COG1648	precorrin-2 dehydrogenase activity
OM944_12560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM944_12565	COG0746	molybdenum cofactor guanylyltransferase activity
OM944_12585	COG1704	LemA family
OM944_12605	COG1845	cytochrome c oxidase, subunit III
OM944_12610	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OM944_12615	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM944_12635	COG0693	protein deglycase activity
OM944_12670	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OM944_12685	COG4771	TonB-dependent receptor
OM944_12720	COG0583	DNA-binding transcription factor activity
OM944_12725	COG0673	inositol 2-dehydrogenase activity
OM944_12730	COG1846	Transcriptional regulator
OM944_12735	COG1764	response to oxidative stress
OM944_12740	COG0604	alcohol dehydrogenase
OM944_12740	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_12740	COG3321	synthase
OM944_12765	COG2197	response regulator
OM944_12770	COG4585	Histidine kinase
OM944_12780	COG1473	amidohydrolase
OM944_12790	COG0653	protein targeting
OM944_12795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OM944_12805	COG0668	transmembrane transport
OM944_12810	COG1012	belongs to the aldehyde dehydrogenase family
OM944_12830	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OM944_12855	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_12860	COG2318	DinB family
OM944_12880	COG0708	Exodeoxyribonuclease III
OM944_12885	COG2172	sigma factor antagonist activity
OM944_12890	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OM944_12895	COG0445	tRNA wobble uridine modification
OM944_12910	COG1022	Amp-dependent synthetase and ligase
OM944_12920	COG1024	Enoyl-CoA hydratase
OM944_12920	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM944_12925	COG0183	Belongs to the thiolase family
OM944_12935	COG1960	acyl-CoA dehydrogenase activity
OM944_12940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OM944_12940	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
OM944_12955	COG1090	epimerase
OM944_12960	COG0038	chloride channel
OM944_12965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OM944_12970	COG0569	domain protein
OM944_12975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM944_12980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OM944_12990	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OM944_12995	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OM944_13000	COG2267	carboxylic ester hydrolase activity
OM944_13005	COG1956	GAF domain-containing protein
OM944_13010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM944_13010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM944_13025	COG0232	Belongs to the dGTPase family. Type 2 subfamily
OM944_13100	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM944_13105	COG0598	Magnesium transport protein CorA
OM944_13115	COG0157	Belongs to the NadC ModD family
OM944_13125	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OM944_13135	COG0154	amidase activity
OM944_13150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM944_13150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM944_13155	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OM944_13180	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OM944_13205	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OM944_13225	COG1595	DNA-templated transcription, initiation
OM944_13315	COG2860	membrane
OM944_13320	COG1073	alpha beta
OM944_13320	COG2226	methyltransferase
OM944_13360	COG0432	Pfam Uncharacterised protein family UPF0047
OM944_13385	COG2226	methyltransferase
OM944_13395	COG0352	thiamine-phosphate diphosphorylase activity
OM944_13445	COG2133	pyrroloquinoline quinone binding
OM944_13450	COG3290	protein histidine kinase activity
OM944_13455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OM944_13465	COG4464	protein tyrosine phosphatase activity
OM944_13480	COG1809	phosphosulfolactate synthase activity
OM944_13490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OM944_13495	COG0788	formyltetrahydrofolate deformylase activity
OM944_13505	COG0519	Catalyzes the synthesis of GMP from XMP
OM944_13520	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OM944_13525	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OM944_13555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM944_13565	COG2154	pterin-4-alpha-carbinolamine dehydratase
OM944_13570	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OM944_13595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OM944_13600	COG0805	protein transport
OM944_13605	COG0698	ribose 5-phosphate isomerase
OM944_13615	COG2819	hydrolase of the alpha beta superfamily
OM944_13725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OM944_13730	COG4591	ABC-type transport system involved in lipoprotein release permease component
OM944_13745	COG1132	(ABC) transporter
OM944_13780	COG4771	TonB-dependent receptor
OM944_13805	COG1473	amidohydrolase
OM944_13815	COG1187	pseudouridine synthase activity
OM944_13820	COG0714	Associated with various cellular activities
OM944_13830	COG4206	TonB-dependent receptor
OM944_13830	COG1629	transport
OM944_13855	COG0544	peptidyl-prolyl cis-trans isomerase activity
OM944_13865	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OM944_13870	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
OM944_13875	COG0793	Belongs to the peptidase S41A family
OM944_13875	COG4946	Tricorn protease homolog
OM944_13915	COG2226	methyltransferase
OM944_13920	COG0668	transmembrane transport
OM944_13945	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OM944_13950	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OM944_13970	COG1595	DNA-templated transcription, initiation
OM944_14025	COG1858	cytochrome C peroxidase
OM944_14050	COG1187	pseudouridine synthase activity
OM944_14060	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OM944_14080	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OM944_14085	COG4584	PFAM Integrase catalytic
OM944_14090	COG1484	DNA-dependent DNA replication
OM944_14105	COG1061	Type III restriction enzyme res subunit
OM944_14185	COG4206	TonB-dependent receptor
OM944_14185	COG1629	transport
OM944_14215	COG3279	Response regulator of the LytR AlgR family
OM944_14245	COG4251	negative regulation of phosphorylation
OM944_14250	COG3530	Putative quorum-sensing-regulated virulence factor
OM944_14275	COG2201	protein-glutamate methylesterase activity
OM944_14300	COG3119	arylsulfatase activity
OM944_14305	COG3119	arylsulfatase activity
OM944_14310	COG0714	Associated with various cellular activities
OM944_14325	COG2304	oxidoreductase activity
OM944_14330	COG2304	oxidoreductase activity
OM944_14365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM944_14375	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OM944_14385	COG2610	gluconate transmembrane transporter activity
OM944_14400	COG0556	nucleotide-excision repair
OM944_14410	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OM944_14435	COG0564	pseudouridine synthase activity
OM944_14460	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OM944_14465	COG1381	Involved in DNA repair and RecF pathway recombination
OM944_14470	COG1435	thymidine kinase activity
OM944_14495	COG0772	Belongs to the SEDS family
OM944_14500	COG0768	penicillin binding
OM944_14515	COG1077	Cell shape determining protein MreB Mrl
OM944_14520	COG0779	Required for maturation of 30S ribosomal subunits
OM944_14525	COG0195	Participates in both transcription termination and antitermination
OM944_14525	COG2251	uridine kinase activity
OM944_14530	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OM944_14530	COG5180	pathogenesis
OM944_14565	COG1966	Carbon starvation protein
OM944_14570	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OM944_14595	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OM944_14600	COG1187	pseudouridine synthase activity
OM944_14605	COG3118	belongs to the thioredoxin family
OM944_14625	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OM944_14635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OM944_14660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OM944_14665	COG0450	alkyl hydroperoxide reductase
OM944_14690	COG3781	membrane
OM944_14695	COG0237	dephospho-CoA kinase activity
OM944_14705	COG1862	Preprotein translocase
OM944_14730	COG1132	(ABC) transporter
OM944_14740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM944_14745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM944_14755	COG1366	Belongs to the anti-sigma-factor antagonist family
OM944_14760	COG2208	phosphoserine phosphatase activity
OM944_14770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM944_14795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM944_14815	COG0322	excinuclease ABC activity
OM944_14840	COG0356	it plays a direct role in the translocation of protons across the membrane
OM944_14845	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OM944_14850	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OM944_14855	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OM944_14860	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OM944_14865	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OM944_14875	COG4771	TonB-dependent receptor
OM944_14880	COG3720	iron ion transport
OM944_14885	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OM944_14890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM944_14900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OM944_14925	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OM944_14930	COG4974	Belongs to the 'phage' integrase family
OM944_14950	COG0463	Glycosyl transferase, family 2
OM944_14965	COG0284	orotidine-5'-phosphate decarboxylase activity
OM944_14980	COG1054	Belongs to the UPF0176 family
OM944_14985	COG0813	purine-nucleoside phosphorylase activity
OM944_14995	COG2197	response regulator
OM944_15000	COG4585	Histidine kinase
OM944_15015	COG0778	Nitroreductase
OM944_15030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM944_15040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OM944_15055	COG0527	aspartate kinase activity
OM944_15060	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OM944_15070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OM944_15075	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OM944_15085	COG0347	Belongs to the P(II) protein family
OM944_15090	COG0004	ammonium transporteR
OM944_15105	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OM944_15130	COG3956	TIGRFAM MazG family protein
OM944_15145	COG1104	cysteine desulfurase activity
OM944_15160	COG0531	amino acid
OM944_15165	COG4993	Dehydrogenase
OM944_15170	COG2259	Doxx family
OM944_15175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OM944_15225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OM944_15230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OM944_15235	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OM944_15240	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OM944_15250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM944_15255	COG3938	Belongs to the proline racemase family
OM944_15265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM944_15315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM944_15315	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
OM944_15335	COG0335	large ribosomal subunit rRNA binding
OM944_15340	COG0336	Belongs to the RNA methyltransferase TrmD family
OM944_15345	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OM944_15350	COG0228	four-way junction DNA binding
OM944_15360	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_15365	COG3386	PFAM SMP-30 Gluconolaconase
OM944_15375	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OM944_15380	COG0596	Alpha beta hydrolase
OM944_15385	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OM944_15390	COG1610	YqeY-like protein
OM944_15410	COG1674	ftsk spoiiie
OM944_15415	COG0167	dihydroorotate dehydrogenase activity
OM944_15420	COG1473	amidohydrolase
OM944_15425	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_15455	COG4628	conserved protein (DUF2132)
OM944_15460	COG0346	lactoylglutathione lyase activity
OM944_15470	COG3119	arylsulfatase activity
OM944_15475	COG3119	arylsulfatase activity
OM944_15480	COG4251	negative regulation of phosphorylation
OM944_15485	COG2201	protein-glutamate methylesterase activity
OM944_15505	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_15510	COG0129	dihydroxy-acid dehydratase activity
OM944_15520	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OM944_15540	COG1595	DNA-templated transcription, initiation
OM944_15550	COG0194	GDP metabolic process
OM944_15555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OM944_15585	COG3387	PFAM Glycoside hydrolase 15-related
OM944_15600	COG0316	Belongs to the HesB IscA family
OM944_15620	COG0702	epimerase
OM944_15625	COG1490	D-aminoacyl-tRNA deacylase activity
OM944_15630	COG1119	ATPase activity
OM944_15655	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OM944_15675	COG0233	cytoplasmic translational termination
OM944_15680	COG0528	UMP kinase activity
OM944_15685	COG4770	biotin carboxylase activity
OM944_15730	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OM944_15735	COG0081	regulation of translation
OM944_15740	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OM944_15745	COG0222	ribosome binding
OM944_15750	COG0085	RNA polymerase activity
OM944_15755	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OM944_15775	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OM944_15780	COG0049	tRNA binding
OM944_15785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OM944_15790	COG0051	transcription antitermination factor activity, RNA binding
OM944_15795	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OM944_15800	COG0088	Forms part of the polypeptide exit tunnel
OM944_15805	COG0089	rRNA binding
OM944_15810	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OM944_15815	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OM944_15820	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OM944_15825	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OM944_15830	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OM944_15835	COG0255	Belongs to the universal ribosomal protein uL29 family
OM944_15840	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OM944_15845	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OM944_15850	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OM944_15855	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OM944_15860	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OM944_15865	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OM944_15870	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OM944_15875	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OM944_15880	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OM944_15885	COG1841	ribosomal large subunit assembly
OM944_15890	COG0200	Binds to the 23S rRNA
OM944_15895	COG0201	protein transport
OM944_15905	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OM944_15910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OM944_15915	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OM944_15920	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OM944_15925	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OM944_15930	COG0202	RNA polymerase activity
OM944_15935	COG0203	ribosomal protein L17
OM944_15940	COG0505	Belongs to the CarA family
OM944_15945	COG0148	phosphopyruvate hydratase activity
OM944_15960	COG1045	serine acetyltransferase
OM944_15995	COG0668	transmembrane transport
OM944_16005	COG0039	L-malate dehydrogenase activity
OM944_16015	COG0037	tRNA processing
OM944_16050	COG0497	DNA recombination
OM944_16055	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OM944_16060	COG0596	Alpha beta hydrolase
OM944_16065	COG1846	Transcriptional regulator
OM944_16070	COG2353	YceI-like domain
OM944_16075	COG0346	lactoylglutathione lyase activity
OM944_16090	COG0419	ATPase involved in DNA repair
OM944_16095	COG0420	3'-5' exonuclease activity
OM944_16100	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OM944_16115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM944_16145	COG0022	dehydrogenase e1 component
OM944_16150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM944_16180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM944_16190	COG0612	Peptidase, M16
OM944_16205	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OM944_16210	COG0594	ribonuclease P activity
OM944_16215	COG0793	Belongs to the peptidase S41A family
OM944_16220	COG1214	PFAM Peptidase M22, glycoprotease
OM944_16255	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM944_16255	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OM944_16265	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OM944_16270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OM944_16280	COG0142	geranyltranstransferase activity
OM944_16285	COG0557	exoribonuclease II activity
OM944_16300	COG0321	lipoyl(octanoyl) transferase activity
OM944_16305	COG0792	nuclease activity
OM944_16320	COG0436	Aminotransferase
OM944_16335	COG1216	Glycosyl transferase, family 2
OM944_16345	COG1012	belongs to the aldehyde dehydrogenase family
OM944_16370	COG4206	TonB-dependent receptor
OM944_16385	COG1629	transport
OM944_16385	COG4206	TonB-dependent receptor
OM944_16395	COG3409	Peptidoglycan-binding domain 1 protein
OM944_16395	COG0793	Belongs to the peptidase S41A family
OM944_16405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OM944_16410	COG0242	peptide deformylase activity
OM944_16430	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OM944_16480	COG4654	Cytochrome c, class I
OM944_16490	COG0673	inositol 2-dehydrogenase activity
OM944_16525	COG3237	CsbD-like
OM944_16530	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OM944_16540	COG0006	proline dipeptidase activity
OM944_16560	COG1011	Hydrolase
OM944_16565	COG1012	belongs to the aldehyde dehydrogenase family
OM944_16590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM944_16595	COG1595	DNA-templated transcription, initiation
OM944_16610	COG0584	glycerophosphoryl diester phosphodiesterase
OM944_16620	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OM944_16635	COG1131	(ABC) transporter
OM944_16640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OM944_16745	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
OM944_16750	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OM944_16780	COG1629	transport
OM944_16780	COG4206	TonB-dependent receptor
OM944_16840	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OM944_16845	COG0745	RESPONSE REGULATOR receiver
OM944_16845	COG2205	protein histidine kinase activity
OM944_16845	COG3292	Two component regulator propeller
OM944_16850	COG1629	transport
OM944_16855	COG0702	epimerase
OM944_16870	COG0577	efflux transmembrane transporter activity
OM944_16870	COG1136	(ABC) transporter
OM944_16890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OM944_16895	COG0494	nUDIX hydrolase
OM944_16900	COG0009	L-threonylcarbamoyladenylate synthase
OM944_16910	COG0542	response to heat
OM944_16915	COG1595	DNA-templated transcription, initiation
OM944_16930	COG1796	DNA polymerase
OM944_16930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OM944_16945	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OM944_16950	COG0540	Belongs to the ATCase OTCase family
OM944_16955	COG1131	(ABC) transporter
OM944_17005	COG0437	4 iron, 4 sulfur cluster binding
OM944_17030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OM944_17035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OM944_17040	COG1612	heme a metabolic process
OM944_17045	COG0109	protoheme IX farnesyltransferase activity
OM944_17055	COG1845	cytochrome c oxidase, subunit III
OM944_17065	COG1999	signal sequence binding
OM944_17070	COG2322	membrane
OM944_17080	COG5000	phosphorelay sensor kinase activity
OM944_17090	COG0300	oxidoreductase activity
OM944_17095	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OM944_17105	COG2095	MarC family integral membrane protein
OM944_17125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OM944_17145	COG1193	negative regulation of DNA recombination
OM944_17150	COG0415	Belongs to the DNA photolyase family
OM944_17160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OM944_17165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OM944_17190	COG2076	Multidrug Resistance protein
OM944_17195	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OM944_17225	COG1506	peptidase
OM944_17225	COG0823	Involved in the tonB-independent uptake of proteins
OM944_17235	COG2226	methyltransferase
OM944_17245	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OM944_17270	COG3279	Response regulator of the LytR AlgR family
OM944_17275	COG3275	phosphorelay sensor kinase activity
OM944_17285	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM944_17285	COG0022	dehydrogenase e1 component
OM944_17290	COG1012	belongs to the aldehyde dehydrogenase family
OM944_17295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM944_17310	COG0124	histidyl-tRNA synthetase
OM944_17320	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OM944_17340	COG1629	transport
OM944_17345	COG0702	epimerase
OM944_17360	COG1446	asparaginase
OM944_17375	COG0517	IMP dehydrogenase activity
OM944_17375	COG0516	GMP reductase activity
OM944_17385	COG0193	aminoacyl-tRNA hydrolase activity
OM944_17390	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OM944_17395	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OM944_17425	COG0359	binds to the 23S rRNA
OM944_17430	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OM944_17435	COG0360	Binds together with S18 to 16S ribosomal RNA
OM944_17460	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OM944_17465	COG0681	Belongs to the peptidase S26 family
OM944_17470	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OM944_17480	COG1475	DNA binding
OM944_17485	COG1192	Involved in chromosome partitioning
OM944_17490	COG0706	membrane insertase activity
OM944_17495	COG0504	CTP synthase activity
OM944_17510	COG1595	DNA-templated transcription, initiation
OM944_17525	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OM944_17525	COG0617	tRNA 3'-terminal CCA addition
OM944_17525	COG0517	IMP dehydrogenase activity
OM944_17560	COG2884	Cell division ATP-binding protein ftsE
OM944_17570	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OM944_17590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OM944_17605	COG0512	Glutamine amidotransferase of anthranilate synthase
OM944_17605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OM944_17610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OM944_17615	COG0134	indole-3-glycerol-phosphate synthase activity
OM944_17620	COG0135	phosphoribosylanthranilate isomerase activity
OM944_17625	COG0133	tryptophan synthase activity
OM944_17630	COG0159	tryptophan synthase activity
OM944_17635	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OM944_17640	COG3186	Phenylalanine-4-hydroxylase
OM944_17650	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OM944_17655	COG0107	imidazoleglycerol-phosphate synthase activity
OM944_17660	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OM944_17660	COG0140	phosphoribosyl-ATP diphosphatase activity
OM944_17685	COG0667	Aldo Keto reductase
OM944_17690	COG1217	gtp-binding protein TYPA
OM944_17720	COG2066	Belongs to the glutaminase family
OM944_17735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OM944_17740	COG1127	ABC transporter
OM944_17760	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OM944_17785	COG1774	PSP1 C-terminal conserved region
OM944_17790	COG0151	Belongs to the GarS family
OM944_17795	COG0514	ATP-dependent DNA helicase (RecQ)
OM944_17800	COG0517	IMP dehydrogenase activity
OM944_17800	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OM944_17805	COG0662	Cupin 2, conserved barrel domain protein
OM944_17805	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
OM944_17810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM944_17820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OM944_17835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM944_17835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM944_17860	COG3258	Cytochrome c
OM944_17870	COG3239	Fatty acid desaturase
OM944_17875	COG0513	Belongs to the DEAD box helicase family
OM944_17885	COG1278	Cold shock
OM944_17905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OM944_17905	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OM944_17945	COG0495	leucyl-tRNA aminoacylation
OM944_17950	COG0602	queuosine metabolic process
OM944_17965	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM944_17970	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OM944_17975	COG0740	serine-type endopeptidase activity
OM944_17980	COG0544	peptidyl-prolyl cis-trans isomerase activity
OM944_17990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM944_17995	COG0735	belongs to the Fur family
OM944_18000	COG1366	Belongs to the anti-sigma-factor antagonist family
OM944_18005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OM944_18060	COG0348	domain, Protein
OM944_18075	COG2304	oxidoreductase activity
OM944_18095	COG1193	negative regulation of DNA recombination
OM944_18105	COG1131	(ABC) transporter
OM944_18110	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM944_18115	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM944_18115	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
OM944_18120	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM944_18125	COG1078	dGTPase activity
OM944_18130	COG0745	RESPONSE REGULATOR receiver
OM944_18135	COG0802	atpase or kinase
OM944_18140	COG0686	Belongs to the AlaDH PNT family
OM944_18145	COG2204	response regulator
OM944_18200	COG0481	GTPase activity
OM944_18210	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OM944_18290	COG4145	pantothenate transmembrane transporter activity
OM944_18310	COG2354	Protein conserved in bacteria
OM944_18325	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OM944_18360	COG2819	hydrolase of the alpha beta superfamily
OM944_18370	COG2249	NAD(P)H dehydrogenase (quinone) activity
OM944_18435	COG1570	exodeoxyribonuclease VII activity
OM944_18440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM944_18445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OM944_18450	COG1595	DNA-templated transcription, initiation
OM944_18460	COG4771	TonB-dependent receptor
OM944_18475	COG4948	Mandelate Racemase Muconate Lactonizing
OM944_18485	COG4948	Mandelate Racemase Muconate Lactonizing
OM944_18490	COG0385	Bile acid
OM944_18510	COG5002	protein histidine kinase activity
OM944_18515	COG0745	RESPONSE REGULATOR receiver
OM944_18530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OM944_18535	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM944_18540	COG2814	Major facilitator Superfamily
OM944_18545	COG3119	arylsulfatase activity
OM944_18550	COG0513	Belongs to the DEAD box helicase family
OM944_18570	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_18575	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OM944_18590	COG1704	LemA family
OM944_18600	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
OM944_18605	COG2610	gluconate transmembrane transporter activity
OM944_18640	COG2205	protein histidine kinase activity
OM944_18645	COG1556	Lactate utilization protein
OM944_18650	COG1139	Iron-sulfur cluster binding protein
OM944_18655	COG0247	lactate metabolic process
OM944_18665	COG2188	Transcriptional regulator
OM944_18670	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_18670	COG3347	Dehydrogenase
OM944_18675	COG4952	isomerase
OM944_18680	COG3119	arylsulfatase activity
OM944_18685	COG3386	PFAM SMP-30 Gluconolaconase
OM944_18690	COG0668	transmembrane transport
OM944_18715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OM944_18725	COG2234	aminopeptidase activity
OM944_18730	COG0215	cysteine-tRNA ligase activity
OM944_18735	COG0138	bifunctional purine biosynthesis protein purh
OM944_18745	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OM944_18750	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OM944_18765	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OM944_18775	COG0363	glucosamine-6-phosphate deaminase activity
OM944_18785	COG3265	gluconokinase activity
OM944_18810	COG1472	Belongs to the glycosyl hydrolase 3 family
OM944_18815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OM944_18815	COG0519	Catalyzes the synthesis of GMP from XMP
OM944_18825	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OM944_18830	COG1393	Belongs to the ArsC family
OM944_18855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM944_18860	COG0156	8-amino-7-oxononanoate synthase activity
OM944_18870	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OM944_18875	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OM944_18890	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OM944_18905	COG0442	prolyl-tRNA aminoacylation
OM944_18915	COG4864	UPF0365 protein
OM944_18925	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OM944_18955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM944_18965	COG1215	transferase activity, transferring glycosyl groups
OM944_19025	COG0287	Prephenate dehydrogenase
OM944_19030	COG0436	Aminotransferase
OM944_19035	COG0077	Prephenate dehydratase
OM944_19035	COG1605	Chorismate mutase
OM944_19040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OM944_19045	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OM944_19050	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OM944_19060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OM944_19085	COG1028	Short-chain dehydrogenase reductase Sdr
OM944_19110	COG2211	Major facilitator Superfamily
OM944_19120	COG1649	PFAM Uncharacterised BCR, COG1649
OM944_19130	COG1349	DNA-binding transcription factor activity
OM944_19155	COG1752	Esterase of the alpha-beta hydrolase superfamily
OM944_19185	COG2353	YceI-like domain
OM944_19195	COG0673	inositol 2-dehydrogenase activity
OM944_19205	COG0525	valine-tRNA ligase activity
OM944_19230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM944_19240	COG4206	TonB-dependent receptor
OM944_19240	COG1629	transport
OM944_19265	COG2815	serine threonine protein kinase
OM944_19265	COG0515	serine threonine protein kinase
OM944_19300	COG4452	Inner membrane protein CreD
OM944_19320	COG3279	Response regulator of the LytR AlgR family
OM944_19350	COG1917	Cupin 2, conserved barrel domain protein
OM944_19350	COG2207	Transcriptional regulator
OM944_19360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM944_19375	COG2235	arginine
OM944_19385	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM944_19390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OM944_19420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OM944_19420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OM944_19435	COG1694	Mazg nucleotide pyrophosphohydrolase
OM944_19465	COG0459	protein refolding
OM944_19470	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OM944_19495	COG3604	Transcriptional regulator
OM944_19500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM944_19505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OM944_19520	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OM944_19530	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OM944_19535	COG1051	belongs to the nudix hydrolase family
OM944_19540	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OM944_19560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OM944_19570	COG0024	Methionine aminopeptidase
OM944_19580	COG1115	amino acid carrier protein
OM944_19595	COG0629	single-stranded DNA binding
OM944_19640	COG1609	Transcriptional regulator
OM944_19650	COG1063	alcohol dehydrogenase
OM944_19665	COG2382	esterase
OM944_19675	COG2755	lipolytic protein G-D-S-L family
OM944_19675	COG0657	acetylesterase activity
OM944_19690	COG1629	transport
OM944_19700	COG1629	transport
OM944_19705	COG0702	epimerase
OM944_19725	COG2382	esterase
OM944_19725	COG3693	PFAM glycoside hydrolase, family 10
OM944_19760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OM944_19775	COG1295	ribonuclease BN
OM944_19780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OM944_19790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM944_19800	COG4771	TonB-dependent receptor