locus-tag	class	description
PBT90_00135	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PBT90_00140	COG1381	Involved in DNA repair and RecF pathway recombination
PBT90_00145	COG1435	thymidine kinase activity
PBT90_00170	COG0772	Belongs to the SEDS family
PBT90_00175	COG0768	penicillin binding
PBT90_00190	COG1077	Cell shape determining protein MreB Mrl
PBT90_00195	COG0779	Required for maturation of 30S ribosomal subunits
PBT90_00200	COG0195	Participates in both transcription termination and antitermination
PBT90_00200	COG2251	uridine kinase activity
PBT90_00205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PBT90_00205	COG5180	pathogenesis
PBT90_00240	COG1966	Carbon starvation protein
PBT90_00245	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PBT90_00270	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PBT90_00275	COG1187	pseudouridine synthase activity
PBT90_00280	COG3118	belongs to the thioredoxin family
PBT90_00300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PBT90_00310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PBT90_00335	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PBT90_00340	COG0450	alkyl hydroperoxide reductase
PBT90_00365	COG3781	membrane
PBT90_00370	COG0237	dephospho-CoA kinase activity
PBT90_00380	COG1862	Preprotein translocase
PBT90_00405	COG1132	(ABC) transporter
PBT90_00415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PBT90_00420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PBT90_00430	COG1366	Belongs to the anti-sigma-factor antagonist family
PBT90_00435	COG2208	phosphoserine phosphatase activity
PBT90_00445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PBT90_00470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PBT90_00490	COG0322	excinuclease ABC activity
PBT90_00515	COG0356	it plays a direct role in the translocation of protons across the membrane
PBT90_00520	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PBT90_00525	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PBT90_00530	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PBT90_00535	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PBT90_00540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PBT90_00550	COG4771	TonB-dependent receptor
PBT90_00555	COG3720	iron ion transport
PBT90_00560	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PBT90_00565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBT90_00575	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PBT90_00600	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PBT90_00605	COG4974	Belongs to the 'phage' integrase family
PBT90_00625	COG0463	Glycosyl transferase, family 2
PBT90_00640	COG0284	orotidine-5'-phosphate decarboxylase activity
PBT90_00655	COG1054	Belongs to the UPF0176 family
PBT90_00660	COG0813	purine-nucleoside phosphorylase activity
PBT90_00670	COG2197	response regulator
PBT90_00675	COG4585	Histidine kinase
PBT90_00690	COG0778	Nitroreductase
PBT90_00705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBT90_00715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PBT90_00730	COG0527	aspartate kinase activity
PBT90_00735	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PBT90_00745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PBT90_00750	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PBT90_00760	COG0347	Belongs to the P(II) protein family
PBT90_00765	COG0004	ammonium transporteR
PBT90_00780	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PBT90_00805	COG3956	TIGRFAM MazG family protein
PBT90_00820	COG1104	cysteine desulfurase activity
PBT90_00835	COG0531	amino acid
PBT90_00840	COG4993	Dehydrogenase
PBT90_00845	COG2259	Doxx family
PBT90_00850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PBT90_00900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PBT90_00905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PBT90_00910	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PBT90_00915	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PBT90_00925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PBT90_00930	COG3938	Belongs to the proline racemase family
PBT90_00940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PBT90_00990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PBT90_00990	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
PBT90_01010	COG0335	large ribosomal subunit rRNA binding
PBT90_01015	COG0336	Belongs to the RNA methyltransferase TrmD family
PBT90_01020	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PBT90_01025	COG0228	four-way junction DNA binding
PBT90_01035	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_01040	COG3386	PFAM SMP-30 Gluconolaconase
PBT90_01050	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PBT90_01055	COG0596	Alpha beta hydrolase
PBT90_01060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PBT90_01065	COG1610	YqeY-like protein
PBT90_01085	COG1674	ftsk spoiiie
PBT90_01090	COG0167	dihydroorotate dehydrogenase activity
PBT90_01095	COG1473	amidohydrolase
PBT90_01100	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_01130	COG4628	conserved protein (DUF2132)
PBT90_01135	COG0346	lactoylglutathione lyase activity
PBT90_01145	COG3119	arylsulfatase activity
PBT90_01150	COG3119	arylsulfatase activity
PBT90_01155	COG4251	negative regulation of phosphorylation
PBT90_01160	COG2201	protein-glutamate methylesterase activity
PBT90_01180	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_01185	COG0129	dihydroxy-acid dehydratase activity
PBT90_01195	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PBT90_01215	COG1595	DNA-templated transcription, initiation
PBT90_01225	COG0194	GDP metabolic process
PBT90_01230	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PBT90_01260	COG3387	PFAM Glycoside hydrolase 15-related
PBT90_01275	COG0316	Belongs to the HesB IscA family
PBT90_01295	COG0702	epimerase
PBT90_01300	COG1490	D-aminoacyl-tRNA deacylase activity
PBT90_01305	COG1119	ATPase activity
PBT90_01330	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
PBT90_01350	COG0233	cytoplasmic translational termination
PBT90_01355	COG0528	UMP kinase activity
PBT90_01360	COG4770	biotin carboxylase activity
PBT90_01405	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PBT90_01410	COG0081	regulation of translation
PBT90_01415	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PBT90_01420	COG0222	ribosome binding
PBT90_01425	COG0085	RNA polymerase activity
PBT90_01430	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PBT90_01450	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PBT90_01455	COG0049	tRNA binding
PBT90_01460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PBT90_01465	COG0051	transcription antitermination factor activity, RNA binding
PBT90_01470	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PBT90_01475	COG0088	Forms part of the polypeptide exit tunnel
PBT90_01480	COG0089	rRNA binding
PBT90_01485	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PBT90_01490	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PBT90_01495	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PBT90_01500	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PBT90_01505	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PBT90_01510	COG0255	Belongs to the universal ribosomal protein uL29 family
PBT90_01515	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PBT90_01520	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PBT90_01525	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PBT90_01530	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PBT90_01535	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PBT90_01540	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PBT90_01545	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PBT90_01550	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PBT90_01555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PBT90_01560	COG1841	ribosomal large subunit assembly
PBT90_01565	COG0200	Binds to the 23S rRNA
PBT90_01570	COG0201	protein transport
PBT90_01580	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PBT90_01585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PBT90_01590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PBT90_01595	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PBT90_01600	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PBT90_01605	COG0202	RNA polymerase activity
PBT90_01610	COG0203	ribosomal protein L17
PBT90_01615	COG0505	Belongs to the CarA family
PBT90_01620	COG0148	phosphopyruvate hydratase activity
PBT90_01635	COG1045	serine acetyltransferase
PBT90_01670	COG0668	transmembrane transport
PBT90_01680	COG0039	L-malate dehydrogenase activity
PBT90_01690	COG0037	tRNA processing
PBT90_01725	COG0497	DNA recombination
PBT90_01730	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PBT90_01735	COG0596	Alpha beta hydrolase
PBT90_01740	COG1846	Transcriptional regulator
PBT90_01745	COG2353	YceI-like domain
PBT90_01750	COG0346	lactoylglutathione lyase activity
PBT90_01765	COG0419	ATPase involved in DNA repair
PBT90_01770	COG0420	3'-5' exonuclease activity
PBT90_01775	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PBT90_01790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PBT90_01820	COG0022	dehydrogenase e1 component
PBT90_01825	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PBT90_01850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PBT90_01860	COG0612	Peptidase, M16
PBT90_01875	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PBT90_01880	COG0594	ribonuclease P activity
PBT90_01885	COG0793	Belongs to the peptidase S41A family
PBT90_01890	COG1214	PFAM Peptidase M22, glycoprotease
PBT90_01925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PBT90_01925	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PBT90_01935	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PBT90_01940	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PBT90_01950	COG0142	geranyltranstransferase activity
PBT90_01955	COG0557	exoribonuclease II activity
PBT90_01970	COG0321	lipoyl(octanoyl) transferase activity
PBT90_01975	COG0792	nuclease activity
PBT90_01990	COG0436	Aminotransferase
PBT90_02005	COG1216	Glycosyl transferase, family 2
PBT90_02015	COG1012	belongs to the aldehyde dehydrogenase family
PBT90_02030	COG4206	TonB-dependent receptor
PBT90_02045	COG4206	TonB-dependent receptor
PBT90_02045	COG1629	transport
PBT90_02055	COG0793	Belongs to the peptidase S41A family
PBT90_02055	COG3409	Peptidoglycan-binding domain 1 protein
PBT90_02065	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PBT90_02070	COG0242	peptide deformylase activity
PBT90_02090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PBT90_02135	COG4654	Cytochrome c, class I
PBT90_02145	COG0673	inositol 2-dehydrogenase activity
PBT90_02180	COG3237	CsbD-like
PBT90_02185	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PBT90_02195	COG0006	proline dipeptidase activity
PBT90_02215	COG1011	Hydrolase
PBT90_02220	COG1012	belongs to the aldehyde dehydrogenase family
PBT90_02245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PBT90_02250	COG1595	DNA-templated transcription, initiation
PBT90_02275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PBT90_02290	COG1131	(ABC) transporter
PBT90_02295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PBT90_02385	COG2801	Transposase and inactivated derivatives
PBT90_02450	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PBT90_02485	COG1629	transport
PBT90_02485	COG4206	TonB-dependent receptor
PBT90_02490	COG0702	epimerase
PBT90_02560	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PBT90_02565	COG3292	Two component regulator propeller
PBT90_02565	COG2205	protein histidine kinase activity
PBT90_02565	COG0745	RESPONSE REGULATOR receiver
PBT90_02570	COG1629	transport
PBT90_02575	COG0702	epimerase
PBT90_02580	COG5520	Belongs to the glycosyl hydrolase 30 family
PBT90_02590	COG1136	(ABC) transporter
PBT90_02590	COG0577	efflux transmembrane transporter activity
PBT90_02610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PBT90_02615	COG0494	nUDIX hydrolase
PBT90_02620	COG0009	L-threonylcarbamoyladenylate synthase
PBT90_02630	COG0542	response to heat
PBT90_02635	COG1595	DNA-templated transcription, initiation
PBT90_02650	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PBT90_02650	COG1796	DNA polymerase
PBT90_02665	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PBT90_02670	COG0540	Belongs to the ATCase OTCase family
PBT90_02675	COG1131	(ABC) transporter
PBT90_02725	COG0437	4 iron, 4 sulfur cluster binding
PBT90_02750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PBT90_02755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PBT90_02760	COG1612	heme a metabolic process
PBT90_02765	COG0109	protoheme IX farnesyltransferase activity
PBT90_02775	COG1845	cytochrome c oxidase, subunit III
PBT90_02785	COG1999	signal sequence binding
PBT90_02790	COG2322	membrane
PBT90_02800	COG5000	phosphorelay sensor kinase activity
PBT90_02810	COG0300	oxidoreductase activity
PBT90_02815	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PBT90_02825	COG2095	MarC family integral membrane protein
PBT90_02870	COG0415	Belongs to the DNA photolyase family
PBT90_02880	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PBT90_02885	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PBT90_02910	COG2076	Multidrug Resistance protein
PBT90_02915	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PBT90_02945	COG0823	Involved in the tonB-independent uptake of proteins
PBT90_02945	COG1506	peptidase
PBT90_02955	COG2226	methyltransferase
PBT90_02965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PBT90_02990	COG3279	Response regulator of the LytR AlgR family
PBT90_02995	COG3275	phosphorelay sensor kinase activity
PBT90_03005	COG0022	dehydrogenase e1 component
PBT90_03005	COG0508	dehydrogenase complex catalyzes the overall conversion of
PBT90_03010	COG1012	belongs to the aldehyde dehydrogenase family
PBT90_03015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PBT90_03030	COG0124	histidyl-tRNA synthetase
PBT90_03040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PBT90_03060	COG4771	TonB-dependent receptor
PBT90_03065	COG0702	epimerase
PBT90_03080	COG1446	asparaginase
PBT90_03095	COG0517	IMP dehydrogenase activity
PBT90_03095	COG0516	GMP reductase activity
PBT90_03105	COG0193	aminoacyl-tRNA hydrolase activity
PBT90_03110	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PBT90_03115	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PBT90_03145	COG0359	binds to the 23S rRNA
PBT90_03150	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PBT90_03155	COG0360	Binds together with S18 to 16S ribosomal RNA
PBT90_03180	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PBT90_03185	COG0681	Belongs to the peptidase S26 family
PBT90_03190	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PBT90_03200	COG1475	DNA binding
PBT90_03205	COG1192	Involved in chromosome partitioning
PBT90_03210	COG0706	membrane insertase activity
PBT90_03215	COG0504	CTP synthase activity
PBT90_03230	COG1595	DNA-templated transcription, initiation
PBT90_03245	COG0517	IMP dehydrogenase activity
PBT90_03245	COG0617	tRNA 3'-terminal CCA addition
PBT90_03245	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PBT90_03280	COG2884	Cell division ATP-binding protein ftsE
PBT90_03290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PBT90_03310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PBT90_03325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PBT90_03325	COG0512	Glutamine amidotransferase of anthranilate synthase
PBT90_03330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PBT90_03335	COG0134	indole-3-glycerol-phosphate synthase activity
PBT90_03340	COG0135	phosphoribosylanthranilate isomerase activity
PBT90_03345	COG0133	tryptophan synthase activity
PBT90_03350	COG0159	tryptophan synthase activity
PBT90_03355	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
PBT90_03360	COG3186	Phenylalanine-4-hydroxylase
PBT90_03365	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PBT90_03370	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PBT90_03375	COG0107	imidazoleglycerol-phosphate synthase activity
PBT90_03380	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PBT90_03380	COG0140	phosphoribosyl-ATP diphosphatase activity
PBT90_03405	COG0667	Aldo Keto reductase
PBT90_03410	COG1217	gtp-binding protein TYPA
PBT90_03440	COG2066	Belongs to the glutaminase family
PBT90_03455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PBT90_03460	COG1127	ABC transporter
PBT90_03480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PBT90_03490	COG0166	Belongs to the GPI family
PBT90_03515	COG1774	PSP1 C-terminal conserved region
PBT90_03520	COG0151	Belongs to the GarS family
PBT90_03525	COG0514	ATP-dependent DNA helicase (RecQ)
PBT90_03530	COG0517	IMP dehydrogenase activity
PBT90_03530	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PBT90_03535	COG0662	Cupin 2, conserved barrel domain protein
PBT90_03535	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PBT90_03540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PBT90_03550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PBT90_03565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PBT90_03565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PBT90_03590	COG3258	Cytochrome c
PBT90_03600	COG3239	Fatty acid desaturase
PBT90_03605	COG0513	Belongs to the DEAD box helicase family
PBT90_03615	COG1278	Cold shock
PBT90_03620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PBT90_03635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PBT90_03635	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PBT90_03675	COG0495	leucyl-tRNA aminoacylation
PBT90_03680	COG0602	queuosine metabolic process
PBT90_03695	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT90_03700	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PBT90_03705	COG0740	serine-type endopeptidase activity
PBT90_03710	COG0544	peptidyl-prolyl cis-trans isomerase activity
PBT90_03720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PBT90_03725	COG0735	belongs to the Fur family
PBT90_03730	COG1366	Belongs to the anti-sigma-factor antagonist family
PBT90_03735	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PBT90_03790	COG0348	domain, Protein
PBT90_03805	COG2304	oxidoreductase activity
PBT90_03825	COG1193	negative regulation of DNA recombination
PBT90_03835	COG1131	(ABC) transporter
PBT90_03840	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT90_03845	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PBT90_03845	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PBT90_03850	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT90_03855	COG1078	dGTPase activity
PBT90_03860	COG0745	RESPONSE REGULATOR receiver
PBT90_03865	COG0802	atpase or kinase
PBT90_03870	COG0686	Belongs to the AlaDH PNT family
PBT90_03875	COG2204	response regulator
PBT90_03940	COG0481	GTPase activity
PBT90_03950	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PBT90_04030	COG4145	pantothenate transmembrane transporter activity
PBT90_04050	COG2354	Protein conserved in bacteria
PBT90_04065	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PBT90_04100	COG2819	hydrolase of the alpha beta superfamily
PBT90_04110	COG2249	NAD(P)H dehydrogenase (quinone) activity
PBT90_04175	COG1570	exodeoxyribonuclease VII activity
PBT90_04180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PBT90_04185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PBT90_04190	COG1595	DNA-templated transcription, initiation
PBT90_04200	COG4771	TonB-dependent receptor
PBT90_04215	COG4948	Mandelate Racemase Muconate Lactonizing
PBT90_04225	COG4948	Mandelate Racemase Muconate Lactonizing
PBT90_04230	COG0385	Bile acid
PBT90_04250	COG5002	protein histidine kinase activity
PBT90_04255	COG0745	RESPONSE REGULATOR receiver
PBT90_04270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PBT90_04275	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PBT90_04280	COG2814	Major facilitator Superfamily
PBT90_04285	COG3119	arylsulfatase activity
PBT90_04290	COG0513	Belongs to the DEAD box helicase family
PBT90_04310	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_04315	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PBT90_04330	COG1704	LemA family
PBT90_04340	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
PBT90_04345	COG2610	gluconate transmembrane transporter activity
PBT90_04380	COG2205	protein histidine kinase activity
PBT90_04385	COG1556	Lactate utilization protein
PBT90_04390	COG1139	Iron-sulfur cluster binding protein
PBT90_04395	COG0247	lactate metabolic process
PBT90_04405	COG2188	Transcriptional regulator
PBT90_04410	COG3347	Dehydrogenase
PBT90_04410	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_04415	COG4952	isomerase
PBT90_04420	COG3119	arylsulfatase activity
PBT90_04425	COG3386	PFAM SMP-30 Gluconolaconase
PBT90_04430	COG0668	transmembrane transport
PBT90_04455	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PBT90_04465	COG2234	aminopeptidase activity
PBT90_04470	COG0215	cysteine-tRNA ligase activity
PBT90_04475	COG0138	bifunctional purine biosynthesis protein purh
PBT90_04485	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PBT90_04490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PBT90_04505	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PBT90_04515	COG0363	glucosamine-6-phosphate deaminase activity
PBT90_04525	COG3265	gluconokinase activity
PBT90_04550	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT90_04555	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PBT90_04555	COG0519	Catalyzes the synthesis of GMP from XMP
PBT90_04565	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PBT90_04570	COG1393	Belongs to the ArsC family
PBT90_04595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBT90_04600	COG0156	8-amino-7-oxononanoate synthase activity
PBT90_04610	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PBT90_04615	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PBT90_04630	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PBT90_04645	COG0442	prolyl-tRNA aminoacylation
PBT90_04655	COG4864	UPF0365 protein
PBT90_04665	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PBT90_04695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PBT90_04705	COG1215	transferase activity, transferring glycosyl groups
PBT90_04765	COG0287	Prephenate dehydrogenase
PBT90_04770	COG0436	Aminotransferase
PBT90_04775	COG0077	Prephenate dehydratase
PBT90_04775	COG1605	Chorismate mutase
PBT90_04780	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PBT90_04785	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PBT90_04790	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PBT90_04800	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PBT90_04825	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_04850	COG2211	Major facilitator Superfamily
PBT90_04860	COG1649	PFAM Uncharacterised BCR, COG1649
PBT90_04870	COG1349	DNA-binding transcription factor activity
PBT90_04895	COG1752	Esterase of the alpha-beta hydrolase superfamily
PBT90_04925	COG2353	YceI-like domain
PBT90_04935	COG0673	inositol 2-dehydrogenase activity
PBT90_04945	COG0525	valine-tRNA ligase activity
PBT90_04970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PBT90_04980	COG4206	TonB-dependent receptor
PBT90_04980	COG1629	transport
PBT90_05005	COG0515	serine threonine protein kinase
PBT90_05005	COG2815	serine threonine protein kinase
PBT90_05040	COG4452	Inner membrane protein CreD
PBT90_05060	COG3279	Response regulator of the LytR AlgR family
PBT90_05100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PBT90_05115	COG2235	arginine
PBT90_05125	COG0860	N-Acetylmuramoyl-L-alanine amidase
PBT90_05130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PBT90_05160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PBT90_05160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PBT90_05175	COG1694	Mazg nucleotide pyrophosphohydrolase
PBT90_05205	COG0459	protein refolding
PBT90_05210	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PBT90_05235	COG3604	Transcriptional regulator
PBT90_05240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PBT90_05245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PBT90_05260	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PBT90_05270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PBT90_05275	COG1051	belongs to the nudix hydrolase family
PBT90_05280	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PBT90_05300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PBT90_05310	COG0024	Methionine aminopeptidase
PBT90_05320	COG1115	amino acid carrier protein
PBT90_05335	COG0629	single-stranded DNA binding
PBT90_05380	COG1609	Transcriptional regulator
PBT90_05390	COG1063	alcohol dehydrogenase
PBT90_05405	COG2382	esterase
PBT90_05415	COG0657	acetylesterase activity
PBT90_05415	COG2755	lipolytic protein G-D-S-L family
PBT90_05430	COG1629	transport
PBT90_05440	COG1629	transport
PBT90_05445	COG0702	epimerase
PBT90_05465	COG3693	PFAM glycoside hydrolase, family 10
PBT90_05465	COG2382	esterase
PBT90_05500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PBT90_05515	COG1295	ribonuclease BN
PBT90_05520	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PBT90_05530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PBT90_05540	COG4771	TonB-dependent receptor
PBT90_05575	COG3279	Response regulator of the LytR AlgR family
PBT90_05630	COG1442	glycosyl transferase family 8
PBT90_05630	COG1216	Glycosyl transferase, family 2
PBT90_05635	COG1215	transferase activity, transferring glycosyl groups
PBT90_05640	COG1132	(ABC) transporter
PBT90_05645	COG0463	Glycosyl transferase, family 2
PBT90_05705	COG4771	TonB-dependent receptor
PBT90_05710	COG0702	epimerase
PBT90_05720	COG2207	Transcriptional regulator
PBT90_05725	COG0693	protein deglycase activity
PBT90_05725	COG0753	catalase activity
PBT90_05740	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_05750	COG1970	mechanosensitive ion channel activity
PBT90_05760	COG0702	epimerase
PBT90_05765	COG1629	transport
PBT90_05805	COG1704	LemA family
PBT90_05865	COG3279	Response regulator of the LytR AlgR family
PBT90_05870	COG0745	RESPONSE REGULATOR receiver
PBT90_05870	COG2972	Histidine kinase
PBT90_05885	COG3279	Response regulator of the LytR AlgR family
PBT90_05915	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PBT90_05930	COG0667	Aldo Keto reductase
PBT90_05955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PBT90_05960	COG2003	Belongs to the UPF0758 family
PBT90_05965	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PBT90_06010	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PBT90_06015	COG0732	type I restriction modification DNA specificity domain
PBT90_06035	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
PBT90_06090	COG2801	Transposase and inactivated derivatives
PBT90_06115	COG2801	Transposase and inactivated derivatives
PBT90_06165	COG4206	TonB-dependent receptor
PBT90_06165	COG1629	transport
PBT90_06195	COG3279	Response regulator of the LytR AlgR family
PBT90_06240	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PBT90_06245	COG4948	Mandelate Racemase Muconate Lactonizing
PBT90_06250	COG2706	6-phosphogluconolactonase activity
PBT90_06255	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PBT90_06315	COG0671	phosphoesterase, PA-phosphatase related
PBT90_06320	COG0408	coproporphyrinogen oxidase activity
PBT90_06330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PBT90_06355	COG2151	metal-sulfur cluster biosynthetic enzyme
PBT90_06360	COG2166	iron-sulfur cluster assembly
PBT90_06365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PBT90_06370	COG0719	Fe-S assembly protein
PBT90_06375	COG0396	ATPase activity
PBT90_06380	COG0719	Fe-S assembly protein
PBT90_06385	COG1522	sequence-specific DNA binding
PBT90_06395	COG0823	Involved in the tonB-independent uptake of proteins
PBT90_06395	COG1506	peptidase
PBT90_06400	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PBT90_06445	COG2244	polysaccharide biosynthetic process
PBT90_06470	COG1215	transferase activity, transferring glycosyl groups
PBT90_06485	COG1215	transferase activity, transferring glycosyl groups
PBT90_06490	COG1216	Glycosyl transferase, family 2
PBT90_06500	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PBT90_06535	COG1216	Glycosyl transferase, family 2
PBT90_06535	COG1442	glycosyl transferase family 8
PBT90_06545	COG0438	transferase activity, transferring glycosyl groups
PBT90_06555	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
PBT90_06575	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PBT90_06605	COG1960	acyl-CoA dehydrogenase activity
PBT90_06625	COG0673	inositol 2-dehydrogenase activity
PBT90_06630	COG1136	(ABC) transporter
PBT90_06630	COG0577	efflux transmembrane transporter activity
PBT90_06650	COG1573	uracil-dna glycosylase
PBT90_06670	COG4771	TonB-dependent receptor
PBT90_06680	COG3119	arylsulfatase activity
PBT90_06695	COG1595	DNA-templated transcription, initiation
PBT90_06745	COG3279	Response regulator of the LytR AlgR family
PBT90_06765	COG0071	Belongs to the small heat shock protein (HSP20) family
PBT90_06775	COG0045	succinate-CoA ligase (ADP-forming) activity
PBT90_06780	COG1136	(ABC) transporter
PBT90_06785	COG0450	alkyl hydroperoxide reductase
PBT90_06795	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PBT90_06800	COG1335	isochorismatase
PBT90_06825	COG1960	acyl-CoA dehydrogenase activity
PBT90_06830	COG0318	PFAM AMP-dependent synthetase and ligase
PBT90_06835	COG3119	arylsulfatase activity
PBT90_06840	COG3119	arylsulfatase activity
PBT90_06845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBT90_06850	COG0110	maltose O-acetyltransferase activity
PBT90_06855	COG1312	Catalyzes the dehydration of D-mannonate
PBT90_06860	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_06865	COG1904	glucuronate isomerase
PBT90_06870	COG1609	Transcriptional regulator
PBT90_06880	COG4771	TonB-dependent receptor
PBT90_06890	COG4771	TonB-dependent receptor
PBT90_06895	COG0673	inositol 2-dehydrogenase activity
PBT90_06905	COG0116	Belongs to the methyltransferase superfamily
PBT90_06905	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PBT90_06920	COG3279	Response regulator of the LytR AlgR family
PBT90_06925	COG2972	Histidine kinase
PBT90_06940	COG1984	allophanate hydrolase subunit 2
PBT90_06945	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PBT90_06965	COG3852	Histidine kinase
PBT90_06970	COG0784	Response regulator, receiver
PBT90_06975	COG4251	negative regulation of phosphorylation
PBT90_06985	COG3237	CsbD-like
PBT90_07000	COG2204	response regulator
PBT90_07005	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
PBT90_07010	COG0513	Belongs to the DEAD box helicase family
PBT90_07020	COG0156	8-amino-7-oxononanoate synthase activity
PBT90_07025	COG4770	biotin carboxylase activity
PBT90_07035	COG0424	maF-like protein
PBT90_07060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PBT90_07090	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PBT90_07115	COG0450	alkyl hydroperoxide reductase
PBT90_07150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PBT90_07185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PBT90_07190	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PBT90_07195	COG0196	riboflavin kinase activity
PBT90_07200	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PBT90_07205	COG1968	undecaprenyl-diphosphatase activity
PBT90_07215	COG2177	Part of the ABC transporter FtsEX involved in
PBT90_07235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PBT90_07245	COG0288	reversible hydration of carbon dioxide
PBT90_07250	COG0659	secondary active sulfate transmembrane transporter activity
PBT90_07255	COG0165	Argininosuccinate lyase
PBT90_07265	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PBT90_07275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PBT90_07280	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PBT90_07285	COG0137	argininosuccinate synthase activity
PBT90_07295	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PBT90_07335	COG1063	alcohol dehydrogenase
PBT90_07360	COG1643	Atp-dependent helicase
PBT90_07375	COG3119	arylsulfatase activity
PBT90_07395	COG4771	TonB-dependent receptor
PBT90_07410	COG0745	RESPONSE REGULATOR receiver
PBT90_07430	COG3408	Glycogen debranching enzyme
PBT90_07430	COG3119	arylsulfatase activity
PBT90_07435	COG0469	pyruvate kinase activity
PBT90_07455	COG1011	Hydrolase
PBT90_07465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PBT90_07485	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PBT90_07490	COG0489	protein tyrosine kinase activity
PBT90_07495	COG0358	DNA primase activity
PBT90_07500	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PBT90_07500	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PBT90_07510	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PBT90_07515	COG2205	protein histidine kinase activity
PBT90_07535	COG0205	6-phosphofructokinase activity
PBT90_07540	COG1803	Methylglyoxal synthase
PBT90_07545	COG1770	oligopeptidase
PBT90_07550	COG1970	mechanosensitive ion channel activity
PBT90_07565	COG1595	DNA-templated transcription, initiation
PBT90_07590	COG0446	pyridine nucleotide-disulphide oxidoreductase
PBT90_07605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PBT90_07615	COG0730	response to heat
PBT90_07650	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PBT90_07655	COG0488	(ABC) transporter
PBT90_07685	COG0825	malonyl-CoA metabolic process
PBT90_07690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PBT90_07695	COG1752	Esterase of the alpha-beta hydrolase superfamily
PBT90_07705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PBT90_07725	COG0187	DNA topoisomerase II activity
PBT90_07730	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PBT90_07735	COG0471	metal ion transport
PBT90_07735	COG3273	potassium ion transport
PBT90_07770	COG0673	inositol 2-dehydrogenase activity
PBT90_07775	COG1917	Cupin 2, conserved barrel domain protein
PBT90_07775	COG2207	Transcriptional regulator
PBT90_07795	COG2010	Cytochrome c
PBT90_07795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PBT90_07800	COG2080	2 iron, 2 sulfur cluster binding
PBT90_07820	COG0798	PFAM Bile acid sodium symporter
PBT90_07830	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PBT90_07870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PBT90_07875	COG3959	Transketolase, thiamine diphosphate binding domain
PBT90_07880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PBT90_07885	COG0739	heme binding
PBT90_07890	COG0179	Fumarylacetoacetate (FAA) hydrolase
PBT90_07910	COG1619	proteins homologs of microcin C7 resistance protein MccF
PBT90_07915	COG2027	D-alanyl-D-alanine carboxypeptidase
PBT90_07920	COG2363	Small membrane protein
PBT90_07945	COG0686	Belongs to the AlaDH PNT family
PBT90_07955	COG0022	dehydrogenase e1 component
PBT90_07970	COG2204	response regulator
PBT90_08005	COG2326	polyphosphate kinase activity
PBT90_08025	COG0439	Biotin carboxylase
PBT90_08030	COG0511	ligase activity, forming carbon-carbon bonds
PBT90_08035	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PBT90_08040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PBT90_08045	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PBT90_08055	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PBT90_08060	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PBT90_08065	COG2239	Acts as a magnesium transporter
PBT90_08070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PBT90_08075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PBT90_08090	COG1321	iron dependent repressor
PBT90_08095	COG4771	TonB-dependent receptor
PBT90_08110	COG2217	Heavy metal translocating P-type atpase
PBT90_08125	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PBT90_08130	COG4771	TonB-dependent receptor
PBT90_08205	COG1428	Deoxynucleoside kinase
PBT90_08210	COG1250	3-hydroxyacyl-CoA dehydrogenase
PBT90_08280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PBT90_08285	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PBT90_08290	COG3104	oligopeptide transport
PBT90_08295	COG1309	transcriptional regulator
PBT90_08300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PBT90_08325	COG0123	including yeast histone deacetylase and acetoin utilization protein
PBT90_08355	COG1115	amino acid carrier protein
PBT90_08360	COG1929	Belongs to the glycerate kinase type-1 family
PBT90_08390	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PBT90_08400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PBT90_08415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PBT90_08420	COG3250	beta-galactosidase activity
PBT90_08435	COG0668	transmembrane transport
PBT90_08450	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PBT90_08490	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PBT90_08495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PBT90_08535	COG2267	carboxylic ester hydrolase activity
PBT90_08540	COG0384	phenazine biosynthesis protein PhzF
PBT90_08545	COG1090	epimerase
PBT90_08555	COG1196	nuclear chromosome segregation
PBT90_08585	COG4952	isomerase
PBT90_08605	COG3254	rhamnose metabolic process
PBT90_08610	COG2755	lipolytic protein G-D-S-L family
PBT90_08635	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PBT90_08645	COG3119	arylsulfatase activity
PBT90_08660	COG4251	negative regulation of phosphorylation
PBT90_08690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PBT90_08710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PBT90_08720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PBT90_08730	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PBT90_08745	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
PBT90_08765	COG2423	ornithine cyclodeaminase activity
PBT90_08770	COG4206	TonB-dependent receptor
PBT90_08775	COG1960	acyl-CoA dehydrogenase activity
PBT90_08800	COG0471	metal ion transport
PBT90_08805	COG3275	phosphorelay sensor kinase activity
PBT90_08810	COG3279	Response regulator of the LytR AlgR family
PBT90_08815	COG2207	Transcriptional regulator
PBT90_08830	COG0673	inositol 2-dehydrogenase activity
PBT90_08835	COG4654	Cytochrome c, class I
PBT90_08860	COG1678	Uncharacterized ACR, COG1678
PBT90_08865	COG0259	pyridoxamine-phosphate oxidase activity
PBT90_08875	COG0739	heme binding
PBT90_08880	COG0492	ferredoxin-NADP+ reductase activity
PBT90_08885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PBT90_08890	COG1185	polyribonucleotide nucleotidyltransferase activity
PBT90_08895	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PBT90_08930	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PBT90_08935	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PBT90_08940	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PBT90_08945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PBT90_08960	COG4206	TonB-dependent receptor
PBT90_08960	COG1629	transport
PBT90_08965	COG0579	oxidoreductase
PBT90_08970	COG0069	glutamate synthase activity
PBT90_08985	COG2081	HI0933 family
PBT90_08990	COG0433	COG0433 Predicted ATPase
PBT90_09010	COG2171	N-acyltransferase activity
PBT90_09025	COG0803	Belongs to the bacterial solute-binding protein 9 family
PBT90_09030	COG1121	(ABC) transporter
PBT90_09035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PBT90_09035	COG1321	iron dependent repressor
PBT90_09040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PBT90_09050	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PBT90_09055	COG4974	Belongs to the 'phage' integrase family
PBT90_09135	COG3177	Filamentation induced by cAMP protein fic
PBT90_09155	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PBT90_09165	COG0784	Response regulator, receiver
PBT90_09180	COG2205	protein histidine kinase activity
PBT90_09190	COG1366	Belongs to the anti-sigma-factor antagonist family
PBT90_09200	COG3279	Response regulator of the LytR AlgR family
PBT90_09205	COG3275	phosphorelay sensor kinase activity
PBT90_09230	COG1793	dna ligase
PBT90_09250	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PBT90_09305	COG0482	sulfurtransferase activity
PBT90_09320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PBT90_09330	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PBT90_09335	COG2086	electron transfer activity
PBT90_09355	COG0604	alcohol dehydrogenase
PBT90_09360	COG0305	Participates in initiation and elongation during chromosome replication
PBT90_09365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PBT90_09370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PBT90_09390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PBT90_09410	COG2234	aminopeptidase activity
PBT90_09415	COG1528	Iron-storage protein
PBT90_09425	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PBT90_09430	COG0307	riboflavin synthase, alpha
PBT90_09435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PBT90_09440	COG1607	acyl-coa hydrolase
PBT90_09450	COG2814	Major facilitator Superfamily
PBT90_09470	COG1621	beta-fructofuranosidase activity
PBT90_09475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT90_09480	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PBT90_09485	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PBT90_09495	COG5492	domain, Protein
PBT90_09515	COG2382	esterase
PBT90_09550	COG0436	Aminotransferase
PBT90_09555	COG0010	Belongs to the arginase family
PBT90_09565	COG0018	arginyl-trna synthetase
PBT90_09570	COG0386	Belongs to the glutathione peroxidase family
PBT90_09575	COG1575	Belongs to the MenA family. Type 1 subfamily
PBT90_09580	COG0589	response to stress
PBT90_09590	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PBT90_09595	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PBT90_09600	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PBT90_09605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PBT90_09605	COG0131	Imidazoleglycerol-phosphate dehydratase
PBT90_09615	COG0463	Glycosyl transferase, family 2
PBT90_09620	COG0577	efflux transmembrane transporter activity
PBT90_09625	COG3876	Protein conserved in bacteria
PBT90_09630	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PBT90_09640	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PBT90_09645	COG0300	oxidoreductase activity
PBT90_09650	COG1546	Belongs to the CinA family
PBT90_09650	COG1058	Belongs to the CinA family
PBT90_09655	COG0508	dehydrogenase complex catalyzes the overall conversion of
PBT90_09660	COG5002	protein histidine kinase activity
PBT90_09660	COG0784	Response regulator, receiver
PBT90_09680	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT90_09680	COG1703	isobutyryl-CoA mutase activity
PBT90_09680	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT90_09685	COG0427	acetyl-CoA hydrolase
PBT90_09690	COG2814	Major facilitator Superfamily
PBT90_09695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PBT90_09700	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PBT90_09715	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PBT90_09735	COG4206	TonB-dependent receptor
PBT90_09740	COG2304	oxidoreductase activity
PBT90_09755	COG0183	Belongs to the thiolase family
PBT90_09765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PBT90_09775	COG1234	tRNA 3'-trailer cleavage
PBT90_09780	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PBT90_09785	COG0513	Belongs to the DEAD box helicase family
PBT90_09790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PBT90_09800	COG0758	DNA mediated transformation
PBT90_09800	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PBT90_09815	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PBT90_09820	COG1410	methionine synthase
PBT90_09820	COG0646	methionine synthase
PBT90_09825	COG0646	methionine synthase
PBT90_09825	COG1410	methionine synthase
PBT90_09835	COG0784	Response regulator, receiver
PBT90_09835	COG2205	protein histidine kinase activity
PBT90_09845	COG0393	Putative heavy-metal-binding
PBT90_09870	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
PBT90_09885	COG0791	NLP P60 protein
PBT90_09885	COG1388	LysM domain
PBT90_09905	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PBT90_09915	COG1136	(ABC) transporter
PBT90_09925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PBT90_09940	COG2814	Major facilitator Superfamily
PBT90_09950	COG0534	Mate efflux family protein
PBT90_09960	COG1522	sequence-specific DNA binding
PBT90_09985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PBT90_10025	COG0745	RESPONSE REGULATOR receiver
PBT90_10035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PBT90_10040	COG1228	amidohydrolase
PBT90_10045	COG0791	NLP P60 protein
PBT90_10065	COG4977	sequence-specific DNA binding
PBT90_10080	COG0534	Mate efflux family protein
PBT90_10085	COG0363	glucosamine-6-phosphate deaminase activity
PBT90_10090	COG0534	Mate efflux family protein
PBT90_10100	COG3483	tryptophan 2,3-dioxygenase activity
PBT90_10105	COG1960	acyl-CoA dehydrogenase activity
PBT90_10130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PBT90_10140	COG1024	Enoyl-CoA hydratase
PBT90_10140	COG1250	3-hydroxyacyl-CoA dehydrogenase
PBT90_10145	COG0784	Response regulator, receiver
PBT90_10145	COG2205	protein histidine kinase activity
PBT90_10170	COG2321	neutral zinc metallopeptidase
PBT90_10175	COG2176	DNA-directed DNA polymerase activity
PBT90_10195	COG1201	RNA secondary structure unwinding
PBT90_10220	COG1914	H( )-stimulated, divalent metal cation uptake system
PBT90_10260	COG0667	Aldo Keto reductase
PBT90_10265	COG1288	antiporter activity
PBT90_10280	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PBT90_10285	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PBT90_10300	COG0848	biopolymer transport protein
PBT90_10305	COG0811	peptide transport
PBT90_10340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PBT90_10365	COG1012	belongs to the aldehyde dehydrogenase family
PBT90_10375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PBT90_10390	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PBT90_10395	COG1404	Belongs to the peptidase S8 family
PBT90_10405	COG0135	phosphoribosylanthranilate isomerase activity
PBT90_10410	COG0656	L-ascorbic acid biosynthetic process
PBT90_10415	COG0702	epimerase
PBT90_10425	COG0673	inositol 2-dehydrogenase activity
PBT90_10455	COG2824	Alkylphosphonate utilization operon protein PhnA
PBT90_10475	COG2329	Antibiotic biosynthesis monooxygenase
PBT90_10500	COG3291	Pkd domain containing protein
PBT90_10515	COG0561	phosphatase activity
PBT90_10520	COG4771	TonB-dependent receptor
PBT90_10530	COG3292	Two component regulator propeller
PBT90_10530	COG2205	protein histidine kinase activity
PBT90_10530	COG0745	RESPONSE REGULATOR receiver
PBT90_10535	COG2115	Belongs to the xylose isomerase family
PBT90_10550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PBT90_10555	COG1760	l-serine dehydratase
PBT90_10585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PBT90_10590	COG4895	conserved protein (DUF2196)
PBT90_10595	COG4807	Protein conserved in bacteria
PBT90_10605	COG3394	polysaccharide catabolic process
PBT90_10630	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PBT90_10640	COG1104	cysteine desulfurase activity
PBT90_10665	COG0673	inositol 2-dehydrogenase activity
PBT90_10690	COG3507	Belongs to the glycosyl hydrolase 43 family
PBT90_10700	COG0596	Alpha beta hydrolase
PBT90_10710	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PBT90_10715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PBT90_10720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PBT90_10725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PBT90_10740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PBT90_10755	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
PBT90_10760	COG0438	transferase activity, transferring glycosyl groups
PBT90_10775	COG1216	Glycosyl transferase, family 2
PBT90_10785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PBT90_10800	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
PBT90_10820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBT90_10830	COG0662	Cupin 2, conserved barrel domain protein
PBT90_10830	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PBT90_10840	COG0489	protein tyrosine kinase activity
PBT90_10850	COG0489	protein tyrosine kinase activity
PBT90_10850	COG3206	protein involved in exopolysaccharide biosynthesis
PBT90_10895	COG4771	TonB-dependent receptor
PBT90_10905	COG1595	DNA-templated transcription, initiation
PBT90_10910	COG0584	glycerophosphoryl diester phosphodiesterase
PBT90_10925	COG4206	TonB-dependent receptor
PBT90_10925	COG1629	transport
PBT90_10945	COG2207	Transcriptional regulator
PBT90_10945	COG1609	Transcriptional regulator
PBT90_11045	COG1629	transport
PBT90_11045	COG4206	TonB-dependent receptor
PBT90_11090	COG1216	Glycosyl transferase, family 2
PBT90_11095	COG1216	Glycosyl transferase, family 2
PBT90_11125	COG0275	rRNA processing
PBT90_11140	COG1215	transferase activity, transferring glycosyl groups
PBT90_11155	COG2852	Protein conserved in bacteria
PBT90_11190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PBT90_11205	COG0463	Glycosyl transferase, family 2
PBT90_11210	COG1216	Glycosyl transferase, family 2
PBT90_11235	COG2801	Transposase and inactivated derivatives
PBT90_11245	COG2153	protein acetylation
PBT90_11250	COG0577	efflux transmembrane transporter activity
PBT90_11255	COG0577	efflux transmembrane transporter activity
PBT90_11260	COG0577	efflux transmembrane transporter activity
PBT90_11270	COG0577	efflux transmembrane transporter activity
PBT90_11275	COG0577	efflux transmembrane transporter activity
PBT90_11300	COG1271	oxidase subunit
PBT90_11305	COG3781	membrane
PBT90_11315	COG0577	efflux transmembrane transporter activity
PBT90_11325	COG2205	protein histidine kinase activity
PBT90_11335	COG0702	epimerase
PBT90_11340	COG4771	TonB-dependent receptor
PBT90_11345	COG1136	(ABC) transporter
PBT90_11345	COG0577	efflux transmembrane transporter activity
PBT90_11350	COG0577	efflux transmembrane transporter activity
PBT90_11355	COG0577	efflux transmembrane transporter activity
PBT90_11355	COG1136	(ABC) transporter
PBT90_11365	COG2204	response regulator
PBT90_11370	COG4191	Histidine kinase
PBT90_11395	COG0714	Associated with various cellular activities
PBT90_11465	COG0667	Aldo Keto reductase
PBT90_11470	COG0205	6-phosphofructokinase activity
PBT90_11480	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PBT90_11485	COG0784	Response regulator, receiver
PBT90_11500	COG0321	lipoyl(octanoyl) transferase activity
PBT90_11500	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PBT90_11510	COG0469	pyruvate kinase activity
PBT90_11520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PBT90_11525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PBT90_11530	COG0571	ribonuclease III activity
PBT90_11535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PBT90_11535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PBT90_11540	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PBT90_11545	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PBT90_11570	COG0339	signal peptide processing
PBT90_11575	COG0628	permease
PBT90_11585	COG0784	Response regulator, receiver
PBT90_11585	COG5002	protein histidine kinase activity
PBT90_11595	COG2205	protein histidine kinase activity
PBT90_11595	COG2198	Histidine kinase
PBT90_11595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PBT90_11595	COG0784	Response regulator, receiver
PBT90_11605	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PBT90_11615	COG0628	permease
PBT90_11620	COG0012	GTP binding
PBT90_11635	COG0488	(ABC) transporter
PBT90_11655	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PBT90_11670	COG2135	peptidase activity
PBT90_11675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PBT90_11700	COG1940	carbohydrate kinase activity
PBT90_11715	COG3119	arylsulfatase activity
PBT90_11720	COG0445	tRNA wobble uridine modification
PBT90_11735	COG4771	TonB-dependent receptor
PBT90_11745	COG4771	TonB-dependent receptor
PBT90_11760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PBT90_11770	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PBT90_11780	COG0577	efflux transmembrane transporter activity
PBT90_11795	COG1663	tetraacyldisaccharide 4'-kinase activity
PBT90_11800	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PBT90_11815	COG0406	alpha-ribazole phosphatase activity
PBT90_11830	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PBT90_11845	COG0583	DNA-binding transcription factor activity
PBT90_11850	COG2986	histidine ammonia-lyase
PBT90_11855	COG1228	amidohydrolase
PBT90_11860	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PBT90_11880	COG3386	PFAM SMP-30 Gluconolaconase
PBT90_11895	COG0247	lactate metabolic process
PBT90_11895	COG0277	FAD linked oxidase domain protein
PBT90_11925	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_11930	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PBT90_11940	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PBT90_11945	COG0346	lactoylglutathione lyase activity
PBT90_11950	COG0316	Belongs to the HesB IscA family
PBT90_11955	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PBT90_11960	COG2045	Belongs to the ComB family
PBT90_11970	COG3119	arylsulfatase activity
PBT90_11980	COG2388	GCN5-related N-acetyl-transferase
PBT90_11985	COG0346	lactoylglutathione lyase activity
PBT90_11990	COG0513	Belongs to the DEAD box helicase family
PBT90_12005	COG2133	pyrroloquinoline quinone binding
PBT90_12020	COG3661	Belongs to the glycosyl hydrolase 67 family
PBT90_12025	COG2514	catechol 2,3-dioxygenase activity
PBT90_12030	COG2267	carboxylic ester hydrolase activity
PBT90_12070	COG3620	sequence-specific DNA binding
PBT90_12090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PBT90_12100	COG2183	response to ionizing radiation
PBT90_12105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT90_12130	COG3757	hydrolase, family 25
PBT90_12175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PBT90_12215	COG3511	phospholipase C
PBT90_12250	COG2116	formate transmembrane transporter activity
PBT90_12260	COG2346	COG2346, Truncated hemoglobins
PBT90_12270	COG0657	acetylesterase activity
PBT90_12270	COG2755	lipolytic protein G-D-S-L family
PBT90_12325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PBT90_12330	COG0673	inositol 2-dehydrogenase activity
PBT90_12335	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_12340	COG0179	Fumarylacetoacetate (FAA) hydrolase
PBT90_12350	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_12355	COG0738	Major facilitator superfamily
PBT90_12365	COG2755	lipolytic protein G-D-S-L family
PBT90_12365	COG0657	acetylesterase activity
PBT90_12380	COG1132	(ABC) transporter
PBT90_12385	COG4974	Belongs to the 'phage' integrase family
PBT90_12440	COG0596	Alpha beta hydrolase
PBT90_12450	COG0739	heme binding
PBT90_12470	COG5002	protein histidine kinase activity
PBT90_12475	COG0745	RESPONSE REGULATOR receiver
PBT90_12495	COG1629	transport
PBT90_12495	COG4206	TonB-dependent receptor
PBT90_12510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PBT90_12530	COG2308	Evidence 4 Homologs of previously reported genes of
PBT90_12535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PBT90_12540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBT90_12540	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBT90_12550	COG0302	gtp cyclohydrolase
PBT90_12565	COG2989	Protein conserved in bacteria
PBT90_12575	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PBT90_12580	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PBT90_12585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PBT90_12585	COG3153	acetyltransferase
PBT90_12590	COG3264	Mechanosensitive ion channel
PBT90_12590	COG1511	domain protein
PBT90_12605	COG0251	oxidation-reduction process
PBT90_12625	COG1725	Transcriptional regulator
PBT90_12635	COG1131	(ABC) transporter
PBT90_12700	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
PBT90_12705	COG4206	TonB-dependent receptor
PBT90_12705	COG1629	transport
PBT90_12720	COG0823	Involved in the tonB-independent uptake of proteins
PBT90_12720	COG1506	peptidase
PBT90_12720	COG4946	Tricorn protease homolog
PBT90_12725	COG0346	lactoylglutathione lyase activity
PBT90_12735	COG1629	transport
PBT90_12765	COG1331	Highly conserved protein containing a thioredoxin domain
PBT90_12770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PBT90_12775	COG5505	Protein of unknown function (DUF819)
PBT90_12800	COG0473	3-isopropylmalate dehydrogenase activity
PBT90_12805	COG1024	Enoyl-CoA hydratase
PBT90_12830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PBT90_12835	COG0154	amidase activity
PBT90_12840	COG0741	lytic transglycosylase activity
PBT90_12840	COG1388	LysM domain
PBT90_12850	COG0280	phosphate acetyltransferase
PBT90_12850	COG0281	malic enzyme
PBT90_12855	COG0632	four-way junction helicase activity
PBT90_12865	COG0509	glycine decarboxylation via glycine cleavage system
PBT90_12885	COG1561	YicC-like family, N-terminal region
PBT90_12895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PBT90_12900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PBT90_12905	COG1183	phosphatidylcholine synthase activity
PBT90_12925	COG1216	Glycosyl transferase, family 2
PBT90_12940	COG1739	Uncharacterized protein family UPF0029
PBT90_12950	COG1757	Na H antiporter
PBT90_12955	COG2072	flavoprotein involved in K transport
PBT90_12990	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_13000	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PBT90_13010	COG0799	negative regulation of ribosome biogenesis
PBT90_13015	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PBT90_13030	COG1047	Peptidyl-prolyl cis-trans
PBT90_13035	COG2204	response regulator
PBT90_13055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PBT90_13070	COG0626	cystathionine gamma-synthase activity
PBT90_13130	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PBT90_13245	COG0110	maltose O-acetyltransferase activity
PBT90_13265	COG0702	epimerase
PBT90_13270	COG3279	Response regulator of the LytR AlgR family
PBT90_13275	COG2972	Histidine kinase
PBT90_13280	COG1131	(ABC) transporter
PBT90_13315	COG1476	TRANSCRIPTIONal
PBT90_13325	COG0004	ammonium transporteR
PBT90_13340	COG1131	(ABC) transporter
PBT90_13350	COG0477	Major facilitator Superfamily
PBT90_13350	COG2814	Major facilitator Superfamily
PBT90_13355	COG0488	(ABC) transporter
PBT90_13365	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PBT90_13375	COG0577	efflux transmembrane transporter activity
PBT90_13375	COG1136	(ABC) transporter
PBT90_13405	COG1999	signal sequence binding
PBT90_13410	COG1981	membrane
PBT90_13420	COG1703	isobutyryl-CoA mutase activity
PBT90_13430	COG3119	arylsulfatase activity
PBT90_13435	COG3119	arylsulfatase activity
PBT90_13450	COG3119	arylsulfatase activity
PBT90_13455	COG4948	Mandelate Racemase Muconate Lactonizing
PBT90_13470	COG4771	TonB-dependent receptor
PBT90_13485	COG3408	Glycogen debranching enzyme
PBT90_13485	COG3119	arylsulfatase activity
PBT90_13510	COG4771	TonB-dependent receptor
PBT90_13530	COG0492	ferredoxin-NADP+ reductase activity
PBT90_13545	COG4774	siderophore transport
PBT90_13590	COG4106	trans-aconitate 2-methyltransferase activity
PBT90_13610	COG2267	carboxylic ester hydrolase activity
PBT90_13615	COG0673	inositol 2-dehydrogenase activity
PBT90_13645	COG0702	epimerase
PBT90_13650	COG1629	transport
PBT90_13660	COG3119	arylsulfatase activity
PBT90_13735	COG3022	response to hydroperoxide
PBT90_13780	COG0017	Asparaginyl-tRNA synthetase
PBT90_13785	COG2814	Major facilitator Superfamily
PBT90_13790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PBT90_13790	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PBT90_13795	COG2270	Major facilitator Superfamily
PBT90_13815	COG0811	peptide transport
PBT90_13830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBT90_13845	COG0673	inositol 2-dehydrogenase activity
PBT90_13850	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_13860	COG0659	secondary active sulfate transmembrane transporter activity
PBT90_13870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PBT90_13875	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PBT90_13875	COG3264	Mechanosensitive ion channel
PBT90_13880	COG1278	Cold shock
PBT90_13890	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_13895	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PBT90_13900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PBT90_13920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PBT90_13925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PBT90_13940	COG4771	TonB-dependent receptor
PBT90_13950	COG4771	TonB-dependent receptor
PBT90_13960	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PBT90_13965	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT90_13970	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT90_13970	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT90_14010	COG0633	Ferredoxin
PBT90_14015	COG0492	ferredoxin-NADP+ reductase activity
PBT90_14025	COG1120	ATPase activity
PBT90_14030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBT90_14055	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PBT90_14065	COG2721	sulfolactate sulfo-lyase activity
PBT90_14100	COG0702	epimerase
PBT90_14105	COG4771	TonB-dependent receptor
PBT90_14115	COG2755	lipolytic protein G-D-S-L family
PBT90_14120	COG2755	lipolytic protein G-D-S-L family
PBT90_14140	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
PBT90_14150	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PBT90_14155	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_14165	COG1904	glucuronate isomerase
PBT90_14170	COG0246	Mannitol dehydrogenase
PBT90_14195	COG1418	mRNA catabolic process
PBT90_14220	COG2003	Belongs to the UPF0758 family
PBT90_14225	COG0268	Binds directly to 16S ribosomal RNA
PBT90_14235	COG0436	Aminotransferase
PBT90_14255	COG1408	metallophosphoesterase
PBT90_14275	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PBT90_14330	COG0488	(ABC) transporter
PBT90_14345	COG3279	Response regulator of the LytR AlgR family
PBT90_14350	COG3275	phosphorelay sensor kinase activity
PBT90_14360	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PBT90_14365	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PBT90_14370	COG1136	(ABC) transporter
PBT90_14370	COG0577	efflux transmembrane transporter activity
PBT90_14375	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PBT90_14385	COG0745	RESPONSE REGULATOR receiver
PBT90_14390	COG5002	protein histidine kinase activity
PBT90_14395	COG0564	pseudouridine synthase activity
PBT90_14400	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PBT90_14405	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PBT90_14410	COG0052	Belongs to the universal ribosomal protein uS2 family
PBT90_14415	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PBT90_14420	COG0006	proline dipeptidase activity
PBT90_14425	COG0612	Peptidase, M16
PBT90_14435	COG1388	LysM domain
PBT90_14435	COG3103	Sh3 type 3 domain protein
PBT90_14435	COG0791	NLP P60 protein
PBT90_14450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PBT90_14490	COG2801	Transposase and inactivated derivatives
PBT90_14495	COG3177	Filamentation induced by cAMP protein fic
PBT90_14505	COG0252	asparaginase activity
PBT90_14510	COG0084	hydrolase, TatD family'
PBT90_14515	COG1215	transferase activity, transferring glycosyl groups
PBT90_14535	COG1215	transferase activity, transferring glycosyl groups
PBT90_14540	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PBT90_14570	COG3457	Alanine racemase
PBT90_14590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PBT90_14595	COG1053	succinate dehydrogenase
PBT90_14610	COG3011	Protein conserved in bacteria
PBT90_14615	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PBT90_14625	COG3655	Transcriptional regulator
PBT90_14635	COG0616	signal peptide processing
PBT90_14645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PBT90_14655	COG0126	phosphoglycerate kinase activity
PBT90_14660	COG0009	L-threonylcarbamoyladenylate synthase
PBT90_14685	COG0514	ATP-dependent DNA helicase (RecQ)
PBT90_14695	COG0658	competence protein
PBT90_14695	COG2333	competence protein COMEC
PBT90_14705	COG2153	protein acetylation
PBT90_14740	COG4181	ATPase activity
PBT90_14785	COG0733	neurotransmitter:sodium symporter activity
PBT90_14800	COG0181	hydroxymethylbilane synthase activity
PBT90_14825	COG0254	rRNA binding
PBT90_14835	COG1132	(ABC) transporter
PBT90_14845	COG0606	chelatase, subunit chli
PBT90_14855	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PBT90_14890	COG0101	tRNA pseudouridine synthase activity
PBT90_14895	COG1132	(ABC) transporter
PBT90_14915	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PBT90_14920	COG0633	Ferredoxin
PBT90_14920	COG3217	Mosc domain protein beta barrel domain protein
PBT90_14925	COG0443	Heat shock 70 kDa protein
PBT90_14945	COG0004	ammonium transporteR
PBT90_14950	COG0113	porphobilinogen synthase activity
PBT90_14955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PBT90_14960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PBT90_14970	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PBT90_14975	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PBT90_14985	COG0552	protein localization to endoplasmic reticulum
PBT90_15015	COG2226	methyltransferase
PBT90_15020	COG1215	transferase activity, transferring glycosyl groups
PBT90_15025	COG0463	Glycosyl transferase, family 2
PBT90_15040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PBT90_15070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PBT90_15085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PBT90_15090	COG0248	Ppx GppA phosphatase
PBT90_15110	COG0673	inositol 2-dehydrogenase activity
PBT90_15140	COG0066	3-isopropylmalate dehydratase activity
PBT90_15145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PBT90_15150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PBT90_15155	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PBT90_15165	COG0028	Belongs to the TPP enzyme family
PBT90_15170	COG0129	dihydroxy-acid dehydratase activity
PBT90_15175	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PBT90_15190	COG0343	queuine tRNA-ribosyltransferase activity
PBT90_15200	COG1595	DNA-templated transcription, initiation
PBT90_15205	COG0357	Ribosomal RNA small subunit methyltransferase G
PBT90_15215	COG3118	belongs to the thioredoxin family
PBT90_15220	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PBT90_15225	COG0709	Synthesizes selenophosphate from selenide and ATP
PBT90_15240	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PBT90_15245	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PBT90_15255	COG1805	sodium ion transport
PBT90_15265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PBT90_15270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PBT90_15275	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PBT90_15290	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PBT90_15295	COG3852	Histidine kinase
PBT90_15300	COG0783	Belongs to the Dps family
PBT90_15305	COG1668	transmembrane transport
PBT90_15310	COG4152	abc transporter atp-binding protein
PBT90_15320	COG0484	heat shock protein binding
PBT90_15325	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PBT90_15330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PBT90_15335	COG0563	adenylate kinase activity
PBT90_15340	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PBT90_15350	COG2885	chlorophyll binding
PBT90_15355	COG2885	chlorophyll binding
PBT90_15360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PBT90_15390	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PBT90_15400	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PBT90_15400	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PBT90_15410	COG0513	Belongs to the DEAD box helicase family
PBT90_15430	COG0438	transferase activity, transferring glycosyl groups
PBT90_15445	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PBT90_15455	COG1162	GTPase activity
PBT90_15465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PBT90_15470	COG3001	Fructosamine kinase
PBT90_15475	COG0673	inositol 2-dehydrogenase activity
PBT90_15480	COG0527	aspartate kinase activity
PBT90_15485	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PBT90_15490	COG2133	pyrroloquinoline quinone binding
PBT90_15495	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PBT90_15515	COG3177	Filamentation induced by cAMP protein fic
PBT90_15525	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PBT90_15530	COG0083	homoserine kinase activity
PBT90_15535	COG0460	homoserine dehydrogenase
PBT90_15535	COG0527	aspartate kinase activity
PBT90_15555	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_15575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBT90_15585	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PBT90_15610	COG0561	phosphatase activity
PBT90_15625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PBT90_15635	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PBT90_15655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PBT90_15665	COG3040	lipid binding
PBT90_15685	COG4206	TonB-dependent receptor
PBT90_15685	COG1629	transport
PBT90_15690	COG1506	peptidase
PBT90_15690	COG0823	Involved in the tonB-independent uptake of proteins
PBT90_15710	COG0542	response to heat
PBT90_15760	COG0508	dehydrogenase complex catalyzes the overall conversion of
PBT90_15775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PBT90_15780	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PBT90_15785	COG0612	Peptidase, M16
PBT90_15790	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PBT90_15815	COG0688	phosphatidylethanolamine metabolic process
PBT90_15820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PBT90_15840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PBT90_15845	COG1373	ATPase (AAA superfamily
PBT90_15850	COG0697	spore germination
PBT90_15870	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PBT90_15885	COG4221	oxidoreductase activity
PBT90_15895	COG2226	methyltransferase
PBT90_15900	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PBT90_15925	COG0328	RNA-DNA hybrid ribonuclease activity
PBT90_15930	COG2095	MarC family integral membrane protein
PBT90_15935	COG1943	Transposase
PBT90_15940	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PBT90_15945	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PBT90_15955	COG4974	Belongs to the 'phage' integrase family
PBT90_15995	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PBT90_16000	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PBT90_16005	COG0772	Belongs to the SEDS family
PBT90_16010	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PBT90_16015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PBT90_16020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PBT90_16025	COG0768	penicillin binding
PBT90_16035	COG0275	rRNA processing
PBT90_16040	COG2001	Belongs to the MraZ family
PBT90_16045	COG0823	Involved in the tonB-independent uptake of proteins
PBT90_16050	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PBT90_16050	COG1648	precorrin-2 dehydrogenase activity
PBT90_16060	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PBT90_16070	COG0175	sulfate reduction
PBT90_16075	COG0175	sulfate reduction
PBT90_16085	COG1959	2 iron, 2 sulfur cluster binding
PBT90_16100	COG0326	Molecular chaperone. Has ATPase activity
PBT90_16120	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PBT90_16140	COG1960	acyl-CoA dehydrogenase activity
PBT90_16150	COG0657	acetylesterase activity
PBT90_16150	COG2755	lipolytic protein G-D-S-L family
PBT90_16155	COG3119	arylsulfatase activity
PBT90_16160	COG0791	NLP P60 protein
PBT90_16170	COG1181	Belongs to the D-alanine--D-alanine ligase family
PBT90_16175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PBT90_16180	COG0475	glutathione-regulated potassium exporter activity
PBT90_16205	COG1569	PIN domain
PBT90_16210	COG3620	sequence-specific DNA binding
PBT90_16220	COG0587	DNA-directed DNA polymerase activity
PBT90_16225	COG0492	ferredoxin-NADP+ reductase activity
PBT90_16235	COG1902	pentaerythritol trinitrate reductase activity
PBT90_16240	COG3682	Transcriptional regulator
PBT90_16265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PBT90_16270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PBT90_16275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PBT90_16280	COG1960	acyl-CoA dehydrogenase activity
PBT90_16300	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBT90_16370	COG2003	Belongs to the UPF0758 family
PBT90_16410	COG0739	heme binding
PBT90_16410	COG0741	lytic transglycosylase activity
PBT90_16410	COG1196	nuclear chromosome segregation
PBT90_16510	COG2197	response regulator
PBT90_16530	COG1192	Involved in chromosome partitioning
PBT90_16545	COG2801	Transposase and inactivated derivatives
PBT90_16860	COG0393	Putative heavy-metal-binding
PBT90_16880	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PBT90_16885	COG1160	GTP binding
PBT90_16900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PBT90_16905	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PBT90_16920	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PBT90_16945	COG0800	Aldolase
PBT90_16980	COG0295	cytidine deaminase activity
PBT90_16990	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PBT90_16995	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
PBT90_17000	COG2807	transmembrane transport
PBT90_17005	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PBT90_17030	COG1595	DNA-templated transcription, initiation
PBT90_17040	COG2181	nitrate reductase activity
PBT90_17040	COG0247	lactate metabolic process
PBT90_17045	COG0247	lactate metabolic process
PBT90_17045	COG2181	nitrate reductase activity
PBT90_17055	COG2885	chlorophyll binding
PBT90_17075	COG1138	Cytochrome C-type biogenesis protein
PBT90_17085	COG1137	ATPase activity
PBT90_17090	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PBT90_17090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PBT90_17100	COG2264	protein methyltransferase activity
PBT90_17105	COG0149	triose-phosphate isomerase activity
PBT90_17110	COG2137	regulation of response to DNA damage stimulus
PBT90_17125	COG0423	glycine-tRNA ligase activity
PBT90_17140	COG0673	inositol 2-dehydrogenase activity
PBT90_17145	COG2197	response regulator
PBT90_17170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PBT90_17180	COG0572	uridine kinase
PBT90_17185	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PBT90_17200	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PBT90_17205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PBT90_17210	COG0363	glucosamine-6-phosphate deaminase activity
PBT90_17215	COG2255	four-way junction helicase activity
PBT90_17220	COG1477	protein flavinylation
PBT90_17235	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBT90_17240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PBT90_17255	COG2176	DNA-directed DNA polymerase activity
PBT90_17255	COG5002	protein histidine kinase activity
PBT90_17280	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PBT90_17285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PBT90_17290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PBT90_17295	COG3844	kynureninase activity
PBT90_17300	COG0662	Cupin 2, conserved barrel domain protein
PBT90_17325	COG2890	protein-(glutamine-N5) methyltransferase activity
PBT90_17335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PBT90_17335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PBT90_17340	COG0516	GMP reductase activity
PBT90_17340	COG0517	IMP dehydrogenase activity
PBT90_17350	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PBT90_17360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PBT90_17365	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT90_17375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PBT90_17395	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PBT90_17400	COG0488	(ABC) transporter
PBT90_17420	COG3119	arylsulfatase activity
PBT90_17435	COG0438	transferase activity, transferring glycosyl groups
PBT90_17445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBT90_17450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBT90_17450	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBT90_17460	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PBT90_17470	COG3622	Belongs to the hyi family
PBT90_17475	COG0673	inositol 2-dehydrogenase activity
PBT90_17480	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PBT90_17480	COG0515	serine threonine protein kinase
PBT90_17495	COG1629	transport
PBT90_17515	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PBT90_17525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PBT90_17535	COG0297	glycogen (starch) synthase activity
PBT90_17540	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PBT90_17545	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PBT90_17560	COG1960	acyl-CoA dehydrogenase activity
PBT90_17570	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PBT90_17590	COG1611	Belongs to the LOG family
PBT90_17605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PBT90_17615	COG3279	Response regulator of the LytR AlgR family
PBT90_17620	COG0745	RESPONSE REGULATOR receiver
PBT90_17635	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PBT90_17640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PBT90_17645	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PBT90_17650	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PBT90_17655	COG3177	Filamentation induced by cAMP protein fic
PBT90_17670	COG2234	aminopeptidase activity
PBT90_17700	COG3046	protein related to deoxyribodipyrimidine photolyase
PBT90_17725	COG0019	diaminopimelate decarboxylase activity
PBT90_17740	COG4948	Mandelate Racemase Muconate Lactonizing
PBT90_17760	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
PBT90_17765	COG1764	response to oxidative stress
PBT90_17775	COG0438	transferase activity, transferring glycosyl groups
PBT90_17785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PBT90_17855	COG3852	Histidine kinase
PBT90_17870	COG0405	Gamma-glutamyltransferase
PBT90_17880	COG1566	PFAM secretion protein HlyD family protein
PBT90_17890	COG2217	Heavy metal translocating P-type atpase
PBT90_17900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PBT90_17915	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PBT90_17940	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PBT90_17950	COG0084	hydrolase, TatD family'
PBT90_17975	COG3250	beta-galactosidase activity
PBT90_17980	COG4804	nuclease activity
PBT90_17995	COG3507	Belongs to the glycosyl hydrolase 43 family
PBT90_18015	COG5564	TIM-barrel signal transduction protein
PBT90_18020	COG3119	arylsulfatase activity
PBT90_18025	COG4585	Histidine kinase
PBT90_18030	COG2197	response regulator
PBT90_18050	COG0784	Response regulator, receiver
PBT90_18050	COG4191	Histidine kinase
PBT90_18065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PBT90_18070	COG3119	arylsulfatase activity
PBT90_18130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PBT90_18130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PBT90_18140	COG2272	Belongs to the type-B carboxylesterase lipase family
PBT90_18160	COG2972	Histidine kinase
PBT90_18180	COG1530	ribonuclease E activity
PBT90_18190	COG0776	regulation of translation
PBT90_18200	COG0629	single-stranded DNA binding
PBT90_18205	COG4535	Mg2 and Co2 transporter CorC
PBT90_18210	COG0069	glutamate synthase activity
PBT90_18210	COG0070	glutamate synthase
PBT90_18210	COG0067	glutamate synthase
PBT90_18225	COG1252	NADH dehydrogenase
PBT90_18230	COG0217	transcriptional regulatory protein
PBT90_18235	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
PBT90_18255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PBT90_18285	COG0590	tRNA wobble adenosine to inosine editing
PBT90_18295	COG1283	sodium-dependent phosphate transmembrane transporter activity
PBT90_18300	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PBT90_18315	COG0545	Peptidyl-prolyl cis-trans isomerase
PBT90_18320	COG0545	Peptidyl-prolyl cis-trans isomerase
PBT90_18325	COG0545	Peptidyl-prolyl cis-trans isomerase
PBT90_18330	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PBT90_18345	COG0105	UTP biosynthetic process
PBT90_18355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PBT90_18360	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PBT90_18360	COG2146	nitrite reductase [NAD(P)H] activity
PBT90_18375	COG2197	response regulator
PBT90_18380	COG2223	nitrite transmembrane transporter activity
PBT90_18385	COG0243	molybdopterin cofactor binding
PBT90_18390	COG1773	rubredoxin
PBT90_18405	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PBT90_18410	COG0315	cyclic pyranopterin monophosphate synthase activity
PBT90_18420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PBT90_18430	COG1648	precorrin-2 dehydrogenase activity
PBT90_18430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PBT90_18435	COG0746	molybdenum cofactor guanylyltransferase activity
PBT90_18455	COG1704	LemA family
PBT90_18475	COG1845	cytochrome c oxidase, subunit III
PBT90_18480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PBT90_18485	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PBT90_18505	COG0693	protein deglycase activity
PBT90_18540	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PBT90_18555	COG4771	TonB-dependent receptor
PBT90_18590	COG0583	DNA-binding transcription factor activity
PBT90_18595	COG0673	inositol 2-dehydrogenase activity
PBT90_18600	COG1846	Transcriptional regulator
PBT90_18605	COG1764	response to oxidative stress
PBT90_18610	COG0604	alcohol dehydrogenase
PBT90_18610	COG3321	synthase
PBT90_18610	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_18635	COG2197	response regulator
PBT90_18640	COG4585	Histidine kinase
PBT90_18650	COG1473	amidohydrolase
PBT90_18660	COG0653	protein targeting
PBT90_18665	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PBT90_18675	COG0668	transmembrane transport
PBT90_18680	COG1012	belongs to the aldehyde dehydrogenase family
PBT90_18700	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PBT90_18725	COG1028	Short-chain dehydrogenase reductase Sdr
PBT90_18730	COG2318	DinB family
PBT90_18750	COG0708	Exodeoxyribonuclease III
PBT90_18755	COG2172	sigma factor antagonist activity
PBT90_18760	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PBT90_18765	COG0445	tRNA wobble uridine modification
PBT90_18780	COG1022	Amp-dependent synthetase and ligase
PBT90_18790	COG1024	Enoyl-CoA hydratase
PBT90_18790	COG1250	3-hydroxyacyl-CoA dehydrogenase
PBT90_18800	COG0183	Belongs to the thiolase family
PBT90_18810	COG1960	acyl-CoA dehydrogenase activity
PBT90_18815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PBT90_18815	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
PBT90_18830	COG1090	epimerase
PBT90_18835	COG0038	chloride channel
PBT90_18840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PBT90_18845	COG0569	domain protein
PBT90_18850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PBT90_18855	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PBT90_18865	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PBT90_18870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PBT90_18875	COG2267	carboxylic ester hydrolase activity
PBT90_18880	COG1956	GAF domain-containing protein
PBT90_18885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PBT90_18885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PBT90_18900	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PBT90_18970	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PBT90_18975	COG0598	Magnesium transport protein CorA
PBT90_18985	COG0157	Belongs to the NadC ModD family
PBT90_18995	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PBT90_19005	COG0154	amidase activity
PBT90_19020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PBT90_19020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PBT90_19025	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PBT90_19050	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PBT90_19075	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PBT90_19095	COG1595	DNA-templated transcription, initiation
PBT90_19180	COG2860	membrane
PBT90_19185	COG2226	methyltransferase
PBT90_19185	COG1073	alpha beta
PBT90_19225	COG0432	Pfam Uncharacterised protein family UPF0047
PBT90_19250	COG2226	methyltransferase
PBT90_19260	COG0352	thiamine-phosphate diphosphorylase activity
PBT90_19310	COG2133	pyrroloquinoline quinone binding
PBT90_19315	COG3290	protein histidine kinase activity
PBT90_19320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PBT90_19330	COG4464	protein tyrosine phosphatase activity
PBT90_19345	COG1809	phosphosulfolactate synthase activity
PBT90_19355	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PBT90_19360	COG0788	formyltetrahydrofolate deformylase activity
PBT90_19370	COG0519	Catalyzes the synthesis of GMP from XMP
PBT90_19385	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PBT90_19390	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PBT90_19420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PBT90_19430	COG2154	pterin-4-alpha-carbinolamine dehydratase
PBT90_19435	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PBT90_19460	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PBT90_19465	COG0805	protein transport
PBT90_19470	COG0698	ribose 5-phosphate isomerase
PBT90_19480	COG2819	hydrolase of the alpha beta superfamily
PBT90_19590	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PBT90_19595	COG4591	ABC-type transport system involved in lipoprotein release permease component
PBT90_19610	COG1132	(ABC) transporter
PBT90_19645	COG4771	TonB-dependent receptor
PBT90_19670	COG1473	amidohydrolase
PBT90_19680	COG1187	pseudouridine synthase activity
PBT90_19685	COG0714	Associated with various cellular activities
PBT90_19695	COG4206	TonB-dependent receptor
PBT90_19695	COG1629	transport
PBT90_19720	COG0544	peptidyl-prolyl cis-trans isomerase activity
PBT90_19730	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PBT90_19735	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PBT90_19740	COG0793	Belongs to the peptidase S41A family
PBT90_19740	COG4946	Tricorn protease homolog
PBT90_19780	COG2226	methyltransferase
PBT90_19785	COG0668	transmembrane transport
PBT90_19810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PBT90_19815	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PBT90_19835	COG1595	DNA-templated transcription, initiation
PBT90_19890	COG1858	cytochrome C peroxidase
PBT90_19915	COG1187	pseudouridine synthase activity
PBT90_19925	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PBT90_19945	COG3525	Glycosyl hydrolase, family 20, catalytic domain
PBT90_19950	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PBT90_19965	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PBT90_19965	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PBT90_19970	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PBT90_19970	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PBT90_19980	COG2801	Transposase and inactivated derivatives
PBT90_20060	COG4206	TonB-dependent receptor
PBT90_20060	COG1629	transport
PBT90_20060	COG4206	TonB-dependent receptor
PBT90_20060	COG1629	transport
PBT90_20090	COG3279	Response regulator of the LytR AlgR family
PBT90_20125	COG3279	Response regulator of the LytR AlgR family
PBT90_20130	COG4251	negative regulation of phosphorylation
PBT90_20135	COG3530	Putative quorum-sensing-regulated virulence factor
PBT90_20185	COG3119	arylsulfatase activity
PBT90_20190	COG3119	arylsulfatase activity
PBT90_20195	COG0714	Associated with various cellular activities
PBT90_20210	COG2304	oxidoreductase activity
PBT90_20215	COG2304	oxidoreductase activity
PBT90_20250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PBT90_20260	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PBT90_20270	COG2610	gluconate transmembrane transporter activity
PBT90_20285	COG0556	nucleotide-excision repair
PBT90_20300	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PBT90_20330	COG0564	pseudouridine synthase activity
PBT90_20345	COG0393	Putative heavy-metal-binding