locus-tag	class	description
A7H1H_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A7H1H_0002	COG0592	DNA-directed DNA polymerase activity
A7H1H_0003	COG0187	DNA topoisomerase II activity
A7H1H_0004	COG0492	ferredoxin-NADP+ reductase activity
A7H1H_0005	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
A7H1H_0007	COG1238	metal cluster binding
A7H1H_0008	COG0500	methyltransferase
A7H1H_0009	COG3842	ATPase activity
A7H1H_0018	COG0564	pseudouridine synthase activity
A7H1H_0019	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A7H1H_0020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7H1H_0021	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7H1H_0027	COG0604	alcohol dehydrogenase
A7H1H_0028	COG1733	regulation of RNA biosynthetic process
A7H1H_0029	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A7H1H_0030	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A7H1H_0034	COG1620	l-lactate permease
A7H1H_0035	COG0745	RESPONSE REGULATOR receiver
A7H1H_0036	COG3852	Histidine kinase
A7H1H_0037	COG1556	Lactate utilization protein
A7H1H_0038	COG1139	Iron-sulfur cluster binding protein
A7H1H_0039	COG0247	lactate metabolic process
A7H1H_0040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7H1H_0041	COG0511	ligase activity, forming carbon-carbon bonds
A7H1H_0042	COG0439	Biotin carboxylase
A7H1H_0043	COG0513	Belongs to the DEAD box helicase family
A7H1H_0044	COG0306	phosphate transporter
A7H1H_0046	COG0367	asparagine synthase
A7H1H_0048	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A7H1H_0049	COG1981	membrane
A7H1H_0050	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A7H1H_0050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A7H1H_0051	COG1187	pseudouridine synthase activity
A7H1H_0052	COG0517	IMP dehydrogenase activity
A7H1H_0052	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A7H1H_0053	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A7H1H_0054	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A7H1H_0055	COG0107	imidazoleglycerol-phosphate synthase activity
A7H1H_0058	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A7H1H_0059	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A7H1H_0060	COG0724	RNA recognition motif
A7H1H_0061	COG0745	RESPONSE REGULATOR receiver
A7H1H_0062	COG0642	Histidine kinase
A7H1H_0073	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A7H1H_0074	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A7H1H_0075	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A7H1H_0078	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7H1H_0079	COG0746	molybdenum cofactor guanylyltransferase activity
A7H1H_0080	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A7H1H_0083	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A7H1H_0084	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A7H1H_0085	COG0268	Binds directly to 16S ribosomal RNA
A7H1H_0086	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A7H1H_0088	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A7H1H_0089	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A7H1H_0090	COG0573	inorganic phosphate transmembrane transporter activity
A7H1H_0091	COG0581	inorganic phosphate transmembrane transporter activity
A7H1H_0092	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A7H1H_0093	COG0704	Plays a role in the regulation of phosphate uptake
A7H1H_0095	COG0745	RESPONSE REGULATOR receiver
A7H1H_0096	COG5002	protein histidine kinase activity
A7H1H_0097	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A7H1H_0098	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A7H1H_0100	COG0546	phosphoglycolate phosphatase activity
A7H1H_0104	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A7H1H_0105	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A7H1H_0108	COG1854	S-ribosylhomocysteine lyase activity
A7H1H_0111	COG1686	Belongs to the peptidase S11 family
A7H1H_0114	COG1410	methionine synthase
A7H1H_0114	COG0646	methionine synthase
A7H1H_0118	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A7H1H_0118	COG0140	phosphoribosyl-ATP diphosphatase activity
A7H1H_0120	COG0489	protein tyrosine kinase activity
A7H1H_0121	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A7H1H_0123	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A7H1H_0123	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A7H1H_0125	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A7H1H_0126	COG0505	Belongs to the CarA family
A7H1H_0128	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A7H1H_0129	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
A7H1H_0130	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A7H1H_0131	COG2353	YceI-like domain
A7H1H_0132	COG1846	Transcriptional regulator
A7H1H_0137	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A7H1H_0138	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A7H1H_0139	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A7H1H_0140	COG0237	dephospho-CoA kinase activity
A7H1H_0141	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A7H1H_0142	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A7H1H_0143	COG0456	acetyltransferase
A7H1H_0160	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A7H1H_0161	COG0254	rRNA binding
A7H1H_0162	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A7H1H_0165	COG0436	Aminotransferase
A7H1H_0166	COG0460	homoserine dehydrogenase
A7H1H_0168	COG0575	Belongs to the CDS family
A7H1H_0169	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A7H1H_0172	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A7H1H_0173	COG0023	Translation Initiation Factor
A7H1H_0174	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A7H1H_0174	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A7H1H_0175	COG1324	tolerance protein
A7H1H_0176	COG2022	thiamine diphosphate biosynthetic process
A7H1H_0191	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A7H1H_0193	COG1346	cytolysis
A7H1H_0195	COG3766	membrane
A7H1H_0196	COG1301	dicarboxylic acid transport
A7H1H_0198	COG0204	Acyl-transferase
A7H1H_0198	COG0318	PFAM AMP-dependent synthetase and ligase
A7H1H_0199	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
A7H1H_0202	COG0666	response to abiotic stimulus
A7H1H_0204	COG0418	dihydroorotase activity
A7H1H_0206	COG1706	bacterial-type flagellum-dependent cell motility
A7H1H_0213	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
A7H1H_0218	COG0037	tRNA processing
A7H1H_0219	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7H1H_0220	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A7H1H_0221	COG0601	transmembrane transport
A7H1H_0222	COG0736	holo-[acyl-carrier-protein] synthase activity
A7H1H_0223	COG0786	glutamate:sodium symporter activity
A7H1H_0224	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A7H1H_0226	COG0560	Phosphoserine phosphatase
A7H1H_0228	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
A7H1H_0229	COG3248	Nucleoside-binding outer membrane protein
A7H1H_0230	COG1393	Belongs to the ArsC family
A7H1H_0231	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A7H1H_0232	COG0343	queuine tRNA-ribosyltransferase activity
A7H1H_0234	COG0436	Aminotransferase
A7H1H_0238	COG2861	carbohydrate metabolic process
A7H1H_0239	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A7H1H_0240	COG0557	exoribonuclease II activity
A7H1H_0241	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
A7H1H_0243	COG0360	Binds together with S18 to 16S ribosomal RNA
A7H1H_0244	COG0629	single-stranded DNA binding
A7H1H_0245	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A7H1H_0247	COG0215	cysteine-tRNA ligase activity
A7H1H_0248	COG0195	Participates in both transcription termination and antitermination
A7H1H_0250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7H1H_0251	COG2121	Domain of unknown function (DUF374)
A7H1H_0253	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
A7H1H_0255	COG0288	reversible hydration of carbon dioxide
A7H1H_0256	COG0156	8-amino-7-oxononanoate synthase activity
A7H1H_0257	COG0792	nuclease activity
A7H1H_0261	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A7H1H_0263	COG0540	Belongs to the ATCase OTCase family
A7H1H_0264	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A7H1H_0266	COG2824	Alkylphosphonate utilization operon protein PhnA
A7H1H_0267	COG1451	nucleotide metabolic process
A7H1H_0268	COG0730	response to heat
A7H1H_0276	COG3328	transposase activity
A7H1H_0277	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A7H1H_0279	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A7H1H_0280	COG0372	Belongs to the citrate synthase family
A7H1H_0281	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A7H1H_0282	COG2828	Protein conserved in bacteria
A7H1H_0284	COG1335	isochorismatase
A7H1H_0285	COG0181	hydroxymethylbilane synthase activity
A7H1H_0287	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A7H1H_0288	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A7H1H_0289	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A7H1H_0290	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A7H1H_0291	COG0450	alkyl hydroperoxide reductase
A7H1H_0293	COG0105	UTP biosynthetic process
A7H1H_0295	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A7H1H_0296	COG0416	fatty acid biosynthetic process
A7H1H_0297	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7H1H_0301	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A7H1H_0302	COG1053	succinate dehydrogenase
A7H1H_0304	COG1007	ATP synthesis coupled electron transport
A7H1H_0306	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7H1H_0307	COG0713	ATP synthesis coupled electron transport
A7H1H_0308	COG0839	Belongs to the complex I subunit 6 family
A7H1H_0309	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7H1H_0310	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A7H1H_0311	COG1034	ATP synthesis coupled electron transport
A7H1H_0312	COG0372	Belongs to the citrate synthase family
A7H1H_0315	COG0649	NAD binding
A7H1H_0315	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7H1H_0316	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7H1H_0317	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7H1H_0318	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A7H1H_0319	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A7H1H_0320	COG3610	response to peptide
A7H1H_0321	COG2966	Psort location CytoplasmicMembrane, score
A7H1H_0323	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
A7H1H_0324	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A7H1H_0334	COG4771	TonB-dependent receptor
A7H1H_0336	COG1971	Probably functions as a manganese efflux pump
A7H1H_0339	COG1132	(ABC) transporter
A7H1H_0340	COG2375	cellular response to nickel ion
A7H1H_0340	COG1132	(ABC) transporter
A7H1H_0341	COG4771	TonB-dependent receptor
A7H1H_0346	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A7H1H_0347	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A7H1H_0347	COG1333	cytochrome c biogenesis protein
A7H1H_0348	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
A7H1H_0349	COG3005	denitrification pathway
A7H1H_0351	COG3287	FIST C domain
A7H1H_0351	COG2200	EAL domain
A7H1H_0351	COG2199	diguanylate cyclase activity
A7H1H_0352	COG0840	transmembrane signaling receptor activity
A7H1H_0356	COG3043	anaerobic respiration
A7H1H_0357	COG0348	domain, Protein
A7H1H_0358	COG0437	4 iron, 4 sulfur cluster binding
A7H1H_0359	COG0243	molybdopterin cofactor binding
A7H1H_0361	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A7H1H_0362	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A7H1H_0364	COG2204	response regulator
A7H1H_0365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A7H1H_0366	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A7H1H_0366	COG1648	precorrin-2 dehydrogenase activity
A7H1H_0369	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A7H1H_0370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A7H1H_0371	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A7H1H_0373	COG2404	hydrolase activity, acting on ester bonds
A7H1H_0374	COG1832	CoA-binding protein
A7H1H_0375	COG0642	Histidine kinase
A7H1H_0376	COG0745	RESPONSE REGULATOR receiver
A7H1H_0377	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A7H1H_0378	COG0191	fructose-bisphosphate aldolase activity
A7H1H_0382	COG0811	peptide transport
A7H1H_0384	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A7H1H_0385	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A7H1H_0387	COG0142	geranyltranstransferase activity
A7H1H_0388	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
A7H1H_0389	COG0442	prolyl-tRNA aminoacylation
A7H1H_0390	COG0668	transmembrane transport
A7H1H_0391	COG0617	tRNA 3'-terminal CCA addition
A7H1H_0394	COG0815	Transfers the fatty acyl group on membrane lipoproteins
A7H1H_0395	COG1862	Preprotein translocase
A7H1H_0396	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7H1H_0397	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7H1H_0400	COG1360	Flagellar Motor Protein
A7H1H_0401	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A7H1H_0403	COG0495	leucyl-tRNA aminoacylation
A7H1H_0405	COG0285	dihydrofolate synthase activity
A7H1H_0413	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A7H1H_0417	COG0745	RESPONSE REGULATOR receiver
A7H1H_0418	COG0642	Histidine kinase
A7H1H_0419	COG2081	HI0933 family
A7H1H_0420	COG0840	transmembrane signaling receptor activity
A7H1H_0423	COG5002	protein histidine kinase activity
A7H1H_0424	COG1692	metallophosphoesterase
A7H1H_0427	COG2226	methyltransferase
A7H1H_0428	COG1570	exodeoxyribonuclease VII activity
A7H1H_0429	COG0835	chemotaxis
A7H1H_0430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A7H1H_0431	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
A7H1H_0432	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A7H1H_0434	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A7H1H_0435	COG0459	protein refolding
A7H1H_0437	COG0745	RESPONSE REGULATOR receiver
A7H1H_0438	COG1408	metallophosphoesterase
A7H1H_0443	COG1136	(ABC) transporter
A7H1H_0447	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A7H1H_0448	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A7H1H_0449	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A7H1H_0450	COG0352	thiamine-phosphate diphosphorylase activity
A7H1H_0451	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
A7H1H_0453	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A7H1H_0454	COG2264	protein methyltransferase activity
A7H1H_0455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7H1H_0458	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A7H1H_0461	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A7H1H_0469	COG1132	(ABC) transporter
A7H1H_0473	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A7H1H_0474	COG1090	epimerase
A7H1H_0475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A7H1H_0479	COG0481	GTPase activity
A7H1H_0480	COG1937	Protein conserved in bacteria
A7H1H_0483	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A7H1H_0485	COG0482	sulfurtransferase activity
A7H1H_0486	COG0482	sulfurtransferase activity
A7H1H_0487	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A7H1H_0488	COG0006	proline dipeptidase activity
A7H1H_0489	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A7H1H_0490	COG0402	S-adenosylhomocysteine deaminase activity
A7H1H_0491	COG0616	signal peptide processing
A7H1H_0501	COG0280	phosphate acetyltransferase
A7H1H_0502	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A7H1H_0504	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A7H1H_0505	COG2176	DNA-directed DNA polymerase activity
A7H1H_0511	COG2176	DNA-directed DNA polymerase activity
A7H1H_0513	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7H1H_0516	COG5002	protein histidine kinase activity
A7H1H_0525	COG1058	Belongs to the CinA family
A7H1H_0525	COG1546	Belongs to the CinA family
A7H1H_0526	COG0579	oxidoreductase
A7H1H_0527	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A7H1H_0531	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A7H1H_0534	COG0667	Aldo Keto reductase
A7H1H_0535	COG0306	phosphate transporter
A7H1H_0536	COG0840	transmembrane signaling receptor activity
A7H1H_0538	COG0840	transmembrane signaling receptor activity
A7H1H_0543	COG0824	Thioesterase
A7H1H_0545	COG0501	Belongs to the peptidase M48B family
A7H1H_0546	COG1322	Protein conserved in bacteria
A7H1H_0550	COG0037	tRNA processing
A7H1H_0554	COG0052	Belongs to the universal ribosomal protein uS2 family
A7H1H_0555	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A7H1H_0556	COG1136	(ABC) transporter
A7H1H_0558	COG0194	GDP metabolic process
A7H1H_0559	COG5002	protein histidine kinase activity
A7H1H_0559	COG5001	Diguanylate cyclase
A7H1H_0560	COG2217	Heavy metal translocating P-type atpase
A7H1H_0563	COG4608	Belongs to the ABC transporter superfamily
A7H1H_0564	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
A7H1H_0565	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A7H1H_0567	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A7H1H_0568	COG1121	(ABC) transporter
A7H1H_0569	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A7H1H_0571	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A7H1H_0575	COG0210	DNA helicase
A7H1H_0576	COG0569	domain protein
A7H1H_0576	COG0475	glutathione-regulated potassium exporter activity
A7H1H_0577	COG0525	valine-tRNA ligase activity
A7H1H_0578	COG4895	conserved protein (DUF2196)
A7H1H_0582	COG2814	Major facilitator Superfamily
A7H1H_0583	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A7H1H_0587	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A7H1H_0588	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A7H1H_0589	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A7H1H_0591	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A7H1H_0597	COG0439	Biotin carboxylase
A7H1H_0598	COG2151	metal-sulfur cluster biosynthetic enzyme
A7H1H_0599	COG2166	iron-sulfur cluster assembly
A7H1H_0600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A7H1H_0602	COG0396	ATPase activity
A7H1H_0603	COG0719	Fe-S assembly protein
A7H1H_0605	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A7H1H_0605	COG0822	iron-sulfur transferase activity
A7H1H_0605	COG2906	2 iron, 2 sulfur cluster binding
A7H1H_0606	COG2239	Acts as a magnesium transporter
A7H1H_0607	COG3706	GGDEF domain
A7H1H_0608	COG0165	Argininosuccinate lyase
A7H1H_0609	COG0835	chemotaxis
A7H1H_0609	COG0784	Response regulator, receiver
A7H1H_0610	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A7H1H_0611	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A7H1H_0613	COG0556	nucleotide-excision repair
A7H1H_0617	COG3328	transposase activity
A7H1H_0618	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A7H1H_0623	COG3328	transposase activity
A7H1H_0624	COG0840	transmembrane signaling receptor activity
A7H1H_0629	COG0698	ribose 5-phosphate isomerase
A7H1H_0630	COG0681	Belongs to the peptidase S26 family
A7H1H_0631	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A7H1H_0632	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A7H1H_0633	COG0193	aminoacyl-tRNA hydrolase activity
A7H1H_0636	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7H1H_0638	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A7H1H_0639	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A7H1H_0641	COG0528	UMP kinase activity
A7H1H_0643	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A7H1H_0644	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A7H1H_0645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A7H1H_0647	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A7H1H_0648	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A7H1H_0650	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
A7H1H_0652	COG0305	Participates in initiation and elongation during chromosome replication
A7H1H_0664	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A7H1H_0666	COG1045	serine acetyltransferase
A7H1H_0681	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A7H1H_0682	COG1086	Polysaccharide biosynthesis protein
A7H1H_0684	COG1793	dna ligase
A7H1H_0685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A7H1H_0686	COG0133	tryptophan synthase activity
A7H1H_0688	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A7H1H_0690	COG0848	biopolymer transport protein
A7H1H_0694	COG1136	(ABC) transporter
A7H1H_0694	COG0577	efflux transmembrane transporter activity
A7H1H_0695	COG1136	(ABC) transporter
A7H1H_0695	COG0577	efflux transmembrane transporter activity
A7H1H_0705	COG0735	belongs to the Fur family
A7H1H_0707	COG0114	fumarate hydratase activity
A7H1H_0710	COG3328	transposase activity
A7H1H_0711	COG3920	Histidine kinase
A7H1H_0712	COG0784	Response regulator, receiver
A7H1H_0713	COG4771	TonB-dependent receptor
A7H1H_0714	COG2819	hydrolase of the alpha beta superfamily
A7H1H_0715	COG0500	methyltransferase
A7H1H_0719	COG1966	Carbon starvation protein
A7H1H_0720	COG0012	GTP binding
A7H1H_0724	COG3123	guanosine phosphorylase activity
A7H1H_0726	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A7H1H_0727	COG0585	pseudouridine synthase activity
A7H1H_0729	COG0840	transmembrane signaling receptor activity
A7H1H_0730	COG0632	four-way junction helicase activity
A7H1H_0731	COG1181	Belongs to the D-alanine--D-alanine ligase family
A7H1H_0736	COG0051	transcription antitermination factor activity, RNA binding
A7H1H_0737	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A7H1H_0738	COG0088	Forms part of the polypeptide exit tunnel
A7H1H_0739	COG0089	rRNA binding
A7H1H_0740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A7H1H_0741	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A7H1H_0742	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A7H1H_0743	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A7H1H_0744	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A7H1H_0745	COG0255	Belongs to the universal ribosomal protein uL29 family
A7H1H_0746	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A7H1H_0747	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A7H1H_0748	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A7H1H_0749	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A7H1H_0750	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A7H1H_0751	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A7H1H_0752	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A7H1H_0753	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A7H1H_0754	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A7H1H_0755	COG0200	Binds to the 23S rRNA
A7H1H_0756	COG0201	protein transport
A7H1H_0757	COG0024	Methionine aminopeptidase
A7H1H_0758	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A7H1H_0759	COG1573	uracil-dna glycosylase
A7H1H_0761	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A7H1H_0764	COG1032	radical SAM domain protein
A7H1H_0766	COG0563	adenylate kinase activity
A7H1H_0770	COG1064	alcohol dehydrogenase
A7H1H_0771	COG1979	alcohol dehydrogenase
A7H1H_0772	COG0840	transmembrane signaling receptor activity
A7H1H_0773	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A7H1H_0774	COG0322	excinuclease ABC activity
A7H1H_0775	COG0840	transmembrane signaling receptor activity
A7H1H_0778	COG0840	transmembrane signaling receptor activity
A7H1H_0779	COG0745	RESPONSE REGULATOR receiver
A7H1H_0781	COG0784	Response regulator, receiver
A7H1H_0781	COG2205	protein histidine kinase activity
A7H1H_0791	COG0829	nickel cation binding
A7H1H_0792	COG0832	Belongs to the urease beta subunit family
A7H1H_0792	COG0831	urea catabolic process
A7H1H_0793	COG0804	urea catabolic process
A7H1H_0794	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
A7H1H_0796	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A7H1H_0805	COG0708	Exodeoxyribonuclease III
A7H1H_0809	COG3040	lipid binding
A7H1H_0812	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A7H1H_0814	COG2200	EAL domain
A7H1H_0815	COG3279	Response regulator of the LytR AlgR family
A7H1H_0816	COG3275	phosphorelay sensor kinase activity
A7H1H_0817	COG1233	COG1233 Phytoene dehydrogenase and related
A7H1H_0818	COG0415	Belongs to the DNA photolyase family
A7H1H_0822	COG0166	Belongs to the GPI family
A7H1H_0831	COG0840	transmembrane signaling receptor activity
A7H1H_0832	COG1942	4-Oxalocrotonate Tautomerase
A7H1H_0833	COG0583	DNA-binding transcription factor activity
A7H1H_0834	COG0134	indole-3-glycerol-phosphate synthase activity
A7H1H_0836	COG0727	PFAM Uncharacterised protein family (UPF0153)
A7H1H_0837	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A7H1H_0839	COG0674	pyruvate-flavodoxin oxidoreductase activity
A7H1H_0839	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A7H1H_0840	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7H1H_0842	COG2176	DNA-directed DNA polymerase activity
A7H1H_0843	COG0135	phosphoribosylanthranilate isomerase activity
A7H1H_0844	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A7H1H_0848	COG1666	GTP binding
A7H1H_0850	COG2363	Small membrane protein
A7H1H_0851	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
A7H1H_0854	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A7H1H_0866	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
A7H1H_0870	COG3177	Filamentation induced by cAMP protein fic
A7H1H_0872	COG1204	response to ionizing radiation
A7H1H_0876	COG4735	regulation of single-species biofilm formation
A7H1H_0881	COG0750	zinc metalloprotease
A7H1H_0882	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A7H1H_0883	COG1028	Short-chain dehydrogenase reductase Sdr
A7H1H_0884	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7H1H_0886	COG0167	dihydroorotate dehydrogenase activity
A7H1H_0887	COG1132	(ABC) transporter
A7H1H_0888	COG0728	peptidoglycan biosynthetic process
A7H1H_0891	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A7H1H_0894	COG3328	transposase activity
A7H1H_0895	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A7H1H_0896	COG3150	esterase
A7H1H_0898	COG0552	protein localization to endoplasmic reticulum
A7H1H_0899	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7H1H_0900	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A7H1H_0901	COG1418	mRNA catabolic process
A7H1H_0902	COG0742	ribosomal rna small subunit methyltransferase
A7H1H_0903	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7H1H_0904	COG0300	oxidoreductase activity
A7H1H_0911	COG3258	Cytochrome c
A7H1H_0913	COG0745	RESPONSE REGULATOR receiver
A7H1H_0914	COG0642	Histidine kinase
A7H1H_0915	COG0157	Belongs to the NadC ModD family
A7H1H_0917	COG1610	YqeY-like protein
A7H1H_0918	COG0488	(ABC) transporter
A7H1H_0920	COG0492	ferredoxin-NADP+ reductase activity
A7H1H_0921	COG0596	Alpha beta hydrolase
A7H1H_0932	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A7H1H_0932	COG0519	Catalyzes the synthesis of GMP from XMP
A7H1H_0933	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A7H1H_0936	COG1451	nucleotide metabolic process
A7H1H_0937	COG0436	Aminotransferase
A7H1H_0938	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A7H1H_0941	COG1696	Membrane protein involved in D-alanine export
A7H1H_0943	COG2223	nitrite transmembrane transporter activity
A7H1H_0945	COG0310	cobalt ion transport
A7H1H_0953	COG3077	Addiction module antitoxin, RelB DinJ family
A7H1H_0956	COG0628	permease
A7H1H_0961	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A7H1H_0963	COG0840	transmembrane signaling receptor activity
A7H1H_0964	COG2200	EAL domain
A7H1H_0964	COG3287	FIST C domain
A7H1H_0964	COG2199	diguanylate cyclase activity
A7H1H_0965	COG0840	transmembrane signaling receptor activity
A7H1H_0966	COG0840	transmembrane signaling receptor activity
A7H1H_0968	COG0730	response to heat
A7H1H_0969	COG1045	serine acetyltransferase
A7H1H_0970	COG1166	arginine decarboxylase activity
A7H1H_0971	COG0124	histidyl-tRNA synthetase
A7H1H_0972	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A7H1H_0973	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A7H1H_0974	COG0163	prenyltransferase activity
A7H1H_0976	COG0359	binds to the 23S rRNA
A7H1H_0977	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
A7H1H_0978	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A7H1H_0980	COG0084	hydrolase, TatD family'
A7H1H_0982	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A7H1H_0983	COG0131	Imidazoleglycerol-phosphate dehydratase
A7H1H_0984	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A7H1H_0987	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A7H1H_0988	COG0456	acetyltransferase
A7H1H_0989	COG1595	DNA-templated transcription, initiation
A7H1H_0999	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A7H1H_1002	COG0784	Response regulator, receiver
A7H1H_1002	COG3437	response regulator, receiver
A7H1H_1004	COG0768	penicillin binding
A7H1H_1008	COG2884	Cell division ATP-binding protein ftsE
A7H1H_1009	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A7H1H_1011	COG0564	pseudouridine synthase activity
A7H1H_1012	COG0772	Belongs to the SEDS family
A7H1H_1014	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A7H1H_1015	COG3123	guanosine phosphorylase activity
A7H1H_1019	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A7H1H_1020	COG0066	3-isopropylmalate dehydratase activity
A7H1H_1021	COG0473	3-isopropylmalate dehydrogenase activity
A7H1H_1024	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A7H1H_1025	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A7H1H_1026	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A7H1H_1027	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A7H1H_1028	COG0202	RNA polymerase activity
A7H1H_1029	COG0203	ribosomal protein L17
A7H1H_1030	COG0154	amidase activity
A7H1H_1031	COG0517	IMP dehydrogenase activity
A7H1H_1031	COG0516	GMP reductase activity
A7H1H_1034	COG0484	heat shock protein binding
A7H1H_1037	COG1119	ATPase activity
A7H1H_1042	COG1733	regulation of RNA biosynthetic process
A7H1H_1043	COG2249	NAD(P)H dehydrogenase (quinone) activity
A7H1H_1045	COG2076	Multidrug Resistance protein
A7H1H_1048	COG1881	PFAM PEBP family protein
A7H1H_1049	COG0583	DNA-binding transcription factor activity
A7H1H_1050	COG2855	membrane
A7H1H_1056	COG1733	regulation of RNA biosynthetic process
A7H1H_1057	COG2249	NAD(P)H dehydrogenase (quinone) activity
A7H1H_1061	COG0778	Nitroreductase
A7H1H_1063	COG0488	(ABC) transporter
A7H1H_1064	COG1607	acyl-coa hydrolase
A7H1H_1066	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A7H1H_1067	COG0754	glutathionylspermidine amidase activity
A7H1H_1071	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A7H1H_1073	COG1496	oxidoreductase activity
A7H1H_1075	COG0788	formyltetrahydrofolate deformylase activity
A7H1H_1076	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A7H1H_1081	COG0745	RESPONSE REGULATOR receiver
A7H1H_1083	COG0330	HflC and HflK could
A7H1H_1087	COG1271	oxidase subunit
A7H1H_1093	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
A7H1H_1095	COG0546	phosphoglycolate phosphatase activity
A7H1H_1097	COG1696	Membrane protein involved in D-alanine export
A7H1H_1103	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
A7H1H_1105	COG0406	alpha-ribazole phosphatase activity
A7H1H_1106	COG1132	(ABC) transporter
A7H1H_1108	COG0745	RESPONSE REGULATOR receiver
A7H1H_1109	COG0642	Histidine kinase
A7H1H_1114	COG0513	Belongs to the DEAD box helicase family
A7H1H_1116	COG0745	RESPONSE REGULATOR receiver
A7H1H_1123	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A7H1H_1125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7H1H_1126	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7H1H_1128	COG0521	Mo-molybdopterin cofactor biosynthetic process
A7H1H_1129	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A7H1H_1130	COG0454	-acetyltransferase
A7H1H_1133	COG0488	(ABC) transporter
A7H1H_1136	COG0243	molybdopterin cofactor binding
A7H1H_1138	COG1193	negative regulation of DNA recombination
A7H1H_1139	COG1253	flavin adenine dinucleotide binding
A7H1H_1141	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7H1H_1142	COG0004	ammonium transporteR
A7H1H_1145	COG0248	Ppx GppA phosphatase
A7H1H_1147	COG0028	Belongs to the TPP enzyme family
A7H1H_1148	COG0440	acetolactate synthase activity
A7H1H_1149	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A7H1H_1150	COG1674	ftsk spoiiie
A7H1H_1150	COG1196	nuclear chromosome segregation
A7H1H_1151	COG0745	RESPONSE REGULATOR receiver
A7H1H_1152	COG0642	Histidine kinase
A7H1H_1170	COG3012	SEC-C Motif Domain Protein
A7H1H_1171	COG0420	3'-5' exonuclease activity
A7H1H_1172	COG0419	ATPase involved in DNA repair
A7H1H_1177	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
A7H1H_1180	COG1160	GTP binding
A7H1H_1181	COG0659	secondary active sulfate transmembrane transporter activity
A7H1H_1185	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A7H1H_1187	COG1185	polyribonucleotide nucleotidyltransferase activity
A7H1H_1189	COG0643	Histidine kinase
A7H1H_1189	COG2198	Histidine kinase
A7H1H_1190	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A7H1H_1191	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
A7H1H_1192	COG2201	protein-glutamate methylesterase activity
A7H1H_1194	COG2223	nitrite transmembrane transporter activity
A7H1H_1195	COG0582	viral genome integration into host DNA
A7H1H_1199	COG0339	signal peptide processing
A7H1H_1200	COG2890	protein-(glutamine-N5) methyltransferase activity
A7H1H_1201	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A7H1H_1202	COG0494	nUDIX hydrolase
A7H1H_1203	COG0527	aspartate kinase activity
A7H1H_1206	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A7H1H_1208	COG0287	Prephenate dehydrogenase
A7H1H_1209	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A7H1H_1210	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
A7H1H_1211	COG0612	Peptidase, M16
A7H1H_1212	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A7H1H_1217	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
A7H1H_1219	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7H1H_1219	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7H1H_1224	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
A7H1H_1229	COG0751	glycine-tRNA ligase activity
A7H1H_1233	COG0357	Ribosomal RNA small subunit methyltransferase G
A7H1H_1234	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A7H1H_1235	COG0113	porphobilinogen synthase activity
A7H1H_1236	COG0784	Response regulator, receiver
A7H1H_1236	COG4191	Histidine kinase
A7H1H_1237	COG0745	RESPONSE REGULATOR receiver
A7H1H_1240	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7H1H_1240	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A7H1H_1241	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A7H1H_1242	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A7H1H_1245	COG1663	tetraacyldisaccharide 4'-kinase activity
A7H1H_1247	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A7H1H_1251	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A7H1H_1252	COG0805	protein transport
A7H1H_1253	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A7H1H_1254	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A7H1H_1255	COG4206	TonB-dependent receptor
A7H1H_1259	COG3328	transposase activity
A7H1H_1264	COG0247	lactate metabolic process
A7H1H_1264	COG2181	nitrate reductase activity
A7H1H_1265	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A7H1H_1269	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
A7H1H_1270	COG2199	diguanylate cyclase activity
A7H1H_1270	COG3287	FIST C domain
A7H1H_1270	COG2200	EAL domain
A7H1H_1271	COG1137	ATPase activity
A7H1H_1272	COG0802	atpase or kinase
A7H1H_1273	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A7H1H_1276	COG0137	argininosuccinate synthase activity
A7H1H_1277	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7H1H_1278	COG1696	Membrane protein involved in D-alanine export
A7H1H_1281	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7H1H_1283	COG0569	domain protein
A7H1H_1284	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A7H1H_1285	COG0745	RESPONSE REGULATOR receiver
A7H1H_1286	COG2205	protein histidine kinase activity
A7H1H_1289	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A7H1H_1290	COG0484	heat shock protein binding
A7H1H_1291	COG0133	tryptophan synthase activity
A7H1H_1295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7H1H_1297	COG2199	diguanylate cyclase activity
A7H1H_1298	COG0500	methyltransferase
A7H1H_1300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A7H1H_1300	COG1333	cytochrome c biogenesis protein
A7H1H_1301	COG2195	Cleaves the N-terminal amino acid of tripeptides
A7H1H_1303	COG0840	transmembrane signaling receptor activity
A7H1H_1306	COG0653	protein targeting
A7H1H_1307	COG4591	ABC-type transport system involved in lipoprotein release permease component
A7H1H_1311	COG0039	L-malate dehydrogenase activity
A7H1H_1316	COG0275	rRNA processing
A7H1H_1318	COG0776	regulation of translation
A7H1H_1324	COG3328	transposase activity
A7H1H_1335	COG1802	Transcriptional regulator
A7H1H_1335	COG4626	Terminase
A7H1H_1340	COG1401	restriction endodeoxyribonuclease activity
A7H1H_1342	COG0270	DNA (cytosine-5-)-methyltransferase activity
A7H1H_1345	COG2026	Addiction module toxin, RelE StbE family
A7H1H_1347	COG4974	Belongs to the 'phage' integrase family
A7H1H_1350	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A7H1H_1352	COG1959	2 iron, 2 sulfur cluster binding
A7H1H_1355	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
A7H1H_1355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7H1H_1357	COG2201	protein-glutamate methylesterase activity
A7H1H_1360	COG0484	heat shock protein binding
A7H1H_1361	COG0789	Transcriptional regulator
A7H1H_1363	COG1131	(ABC) transporter
A7H1H_1364	COG0842	Transport permease protein
A7H1H_1365	COG0842	Transport permease protein
A7H1H_1366	COG0861	Integral membrane protein TerC family
A7H1H_1367	COG1114	Component of the transport system for branched-chain amino acids
A7H1H_1371	COG0582	viral genome integration into host DNA
A7H1H_1392	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A7H1H_1394	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A7H1H_1396	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A7H1H_1398	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A7H1H_1406	COG0488	(ABC) transporter
A7H1H_1407	COG2171	N-acyltransferase activity
A7H1H_1408	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7H1H_1410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A7H1H_1416	COG0309	Hydrogenase expression formation protein (HypE)
A7H1H_1418	COG2084	Dehydrogenase
A7H1H_1419	COG0409	Hydrogenase expression formation protein
A7H1H_1420	COG0298	carbon dioxide binding
A7H1H_1421	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A7H1H_1423	COG0840	transmembrane signaling receptor activity
A7H1H_1424	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7H1H_1426	COG2081	HI0933 family
A7H1H_1430	COG0439	Biotin carboxylase
A7H1H_1436	COG2354	Protein conserved in bacteria
A7H1H_1438	COG2814	Major facilitator Superfamily
A7H1H_1440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7H1H_1440	COG0301	tRNA thio-modification
A7H1H_1444	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A7H1H_1445	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A7H1H_1446	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A7H1H_1447	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
A7H1H_1448	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
A7H1H_1449	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
A7H1H_1450	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A7H1H_1453	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
A7H1H_1454	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
A7H1H_1458	COG1049	propionate catabolic process, 2-methylcitrate cycle
A7H1H_1460	COG5001	Diguanylate cyclase
A7H1H_1460	COG4251	negative regulation of phosphorylation
A7H1H_1460	COG3706	GGDEF domain
A7H1H_1460	COG2203	Gaf domain
A7H1H_1461	COG0217	transcriptional regulatory protein
A7H1H_1462	COG2853	Lipoprotein
A7H1H_1465	COG1611	Belongs to the LOG family
A7H1H_1466	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7H1H_1469	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A7H1H_1473	COG4773	Receptor
A7H1H_1476	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7H1H_1479	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A7H1H_1484	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A7H1H_1485	COG2258	MOSC domain
A7H1H_1486	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A7H1H_1487	COG0095	Lipoate-protein ligase
A7H1H_1488	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A7H1H_1489	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7H1H_1490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7H1H_1491	COG1492	cobalamin metabolic process
A7H1H_1492	COG4773	Receptor
A7H1H_1495	COG0513	Belongs to the DEAD box helicase family
A7H1H_1500	COG1944	ATP diphosphatase activity
A7H1H_1503	COG0840	transmembrane signaling receptor activity
A7H1H_1504	COG0328	RNA-DNA hybrid ribonuclease activity
A7H1H_1505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A7H1H_1510	COG0303	'Molybdopterin
A7H1H_1512	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A7H1H_1514	COG0437	4 iron, 4 sulfur cluster binding
A7H1H_1525	COG1305	Transglutaminase-like
A7H1H_1527	COG0437	4 iron, 4 sulfur cluster binding
A7H1H_1528	COG3383	formate dehydrogenase (NAD+) activity
A7H1H_1528	COG0243	molybdopterin cofactor binding
A7H1H_1530	COG0709	Synthesizes selenophosphate from selenide and ATP
A7H1H_1533	COG1921	L-seryl-tRNASec selenium transferase activity
A7H1H_1546	COG1078	dGTPase activity
A7H1H_1547	COG5001	Diguanylate cyclase
A7H1H_1547	COG5002	protein histidine kinase activity
A7H1H_1548	COG0259	pyridoxamine-phosphate oxidase activity
A7H1H_1550	COG0513	Belongs to the DEAD box helicase family
A7H1H_1554	COG0326	Molecular chaperone. Has ATPase activity
A7H1H_1555	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
A7H1H_1559	COG2995	paraquat-inducible protein a
A7H1H_1562	COG5001	Diguanylate cyclase
A7H1H_1562	COG5002	protein histidine kinase activity
A7H1H_1568	COG4335	DNA alkylation repair
A7H1H_1569	COG2329	Antibiotic biosynthesis monooxygenase
A7H1H_1575	COG1595	DNA-templated transcription, initiation
A7H1H_1576	COG0010	Belongs to the arginase family
A7H1H_1577	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A7H1H_1578	COG2207	Transcriptional regulator
A7H1H_1580	COG0326	Molecular chaperone. Has ATPase activity
A7H1H_1581	COG1609	Transcriptional regulator
A7H1H_1581	COG2207	Transcriptional regulator
A7H1H_1582	COG4771	TonB-dependent receptor
A7H1H_1583	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A7H1H_1584	COG0668	transmembrane transport
A7H1H_1585	COG1227	inorganic diphosphatase activity
A7H1H_1588	COG1027	Aspartate ammonia-lyase
A7H1H_1589	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A7H1H_1590	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A7H1H_1591	COG1047	Peptidyl-prolyl cis-trans
A7H1H_1594	COG0823	Involved in the tonB-independent uptake of proteins
A7H1H_1596	COG0848	biopolymer transport protein
A7H1H_1597	COG0811	peptide transport
A7H1H_1598	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A7H1H_1599	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A7H1H_1600	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A7H1H_1601	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A7H1H_1602	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A7H1H_1603	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A7H1H_1605	COG1475	DNA binding
A7H1H_1606	COG1192	Involved in chromosome partitioning
A7H1H_1609	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A7H1H_1610	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A7H1H_1611	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A7H1H_1612	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A7H1H_1613	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A7H1H_1614	COG0358	DNA primase activity
A7H1H_1616	COG0571	ribonuclease III activity
A7H1H_1617	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A7H1H_1619	COG0501	Belongs to the peptidase M48B family
A7H1H_1623	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A7H1H_1625	COG0706	membrane insertase activity
A7H1H_1626	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A7H1H_1628	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A7H1H_1629	COG0542	response to heat
A7H1H_1630	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A7H1H_1632	COG2326	polyphosphate kinase activity
A7H1H_1634	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A7H1H_1635	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A7H1H_1636	COG0179	Fumarylacetoacetate (FAA) hydrolase
A7H1H_1641	COG0138	bifunctional purine biosynthesis protein purh
A7H1H_1642	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A7H1H_1644	COG0739	heme binding
A7H1H_1645	COG0302	gtp cyclohydrolase
A7H1H_1646	COG0598	Magnesium transport protein CorA
A7H1H_1651	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A7H1H_1652	COG0606	chelatase, subunit chli
A7H1H_1653	COG0840	transmembrane signaling receptor activity
A7H1H_1656	COG0242	peptide deformylase activity
A7H1H_1657	COG0740	serine-type endopeptidase activity
A7H1H_1658	COG0544	peptidyl-prolyl cis-trans isomerase activity
A7H1H_1666	COG0626	cystathionine gamma-synthase activity
A7H1H_1673	COG0745	RESPONSE REGULATOR receiver
A7H1H_1675	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
A7H1H_1678	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A7H1H_1679	COG1858	cytochrome C peroxidase
A7H1H_1685	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A7H1H_1691	COG0351	phosphomethylpyrimidine kinase
A7H1H_1692	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A7H1H_1695	COG0348	domain, Protein
A7H1H_1699	COG4753	response regulator
A7H1H_1699	COG2207	Transcriptional regulator
A7H1H_1701	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A7H1H_1702	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A7H1H_1706	COG0716	FMN binding
A7H1H_1709	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
A7H1H_1710	COG0159	tryptophan synthase activity
A7H1H_1711	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A7H1H_1712	COG2255	four-way junction helicase activity
A7H1H_1713	COG0628	permease
A7H1H_1721	COG0731	radical SAM domain protein
A7H1H_1722	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A7H1H_1724	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A7H1H_1727	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A7H1H_1729	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A7H1H_1731	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A7H1H_1733	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A7H1H_1733	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A7H1H_1734	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
A7H1H_1736	COG3328	transposase activity
A7H1H_1737	COG1368	sulfuric ester hydrolase activity
A7H1H_1738	COG0859	PFAM glycosyl transferase family 9
A7H1H_1742	COG0859	PFAM glycosyl transferase family 9
A7H1H_1743	COG0859	PFAM glycosyl transferase family 9
A7H1H_1745	COG0463	Glycosyl transferase, family 2
A7H1H_1746	COG1083	cytidylyl-transferase
A7H1H_1746	COG2755	lipolytic protein G-D-S-L family
A7H1H_1748	COG2089	acid synthase
A7H1H_1751	COG0438	transferase activity, transferring glycosyl groups
A7H1H_1755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A7H1H_1758	COG0859	PFAM glycosyl transferase family 9
A7H1H_1760	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A7H1H_1762	COG0493	'glutamate synthase
A7H1H_1763	COG0069	glutamate synthase activity
A7H1H_1763	COG0070	glutamate synthase
A7H1H_1763	COG0067	glutamate synthase
A7H1H_1766	COG0840	transmembrane signaling receptor activity
A7H1H_1769	COG1739	Uncharacterized protein family UPF0029
A7H1H_1771	COG0196	riboflavin kinase activity
A7H1H_1772	COG2226	methyltransferase
A7H1H_1773	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A7H1H_1775	COG0277	FAD linked oxidase domain protein
A7H1H_1776	COG1295	ribonuclease BN
A7H1H_1778	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A7H1H_1780	COG2877	3-deoxy-8-phosphooctulonate synthase activity
A7H1H_1782	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A7H1H_1783	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7H1H_1784	COG0284	orotidine-5'-phosphate decarboxylase activity
A7H1H_1790	COG1918	ferrous iron import across plasma membrane
A7H1H_1791	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A7H1H_1791	COG1918	ferrous iron import across plasma membrane
A7H1H_1796	COG2217	Heavy metal translocating P-type atpase
A7H1H_1797	COG0640	Transcriptional regulator
A7H1H_1798	COG4773	Receptor
A7H1H_1800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A7H1H_1803	COG1278	Cold shock
A7H1H_1805	COG2207	Transcriptional regulator
A7H1H_1805	COG4753	response regulator
A7H1H_1806	COG3852	Histidine kinase
A7H1H_1812	COG0450	alkyl hydroperoxide reductase
A7H1H_1813	COG3118	belongs to the thioredoxin family
A7H1H_1816	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A7H1H_1817	COG0085	RNA polymerase activity
A7H1H_1818	COG0222	ribosome binding
A7H1H_1819	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A7H1H_1820	COG0081	regulation of translation
A7H1H_1821	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A7H1H_1822	COG0250	Participates in transcription elongation, termination and antitermination
A7H1H_1825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A7H1H_1826	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A7H1H_1832	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A7H1H_1833	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A7H1H_1834	COG0444	Belongs to the ABC transporter superfamily
A7H1H_1835	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A7H1H_1837	COG1696	Membrane protein involved in D-alanine export
A7H1H_1838	COG0174	glutamine synthetase
A7H1H_1840	COG0314	molybdopterin synthase activity
A7H1H_1842	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
A7H1H_1843	COG1968	undecaprenyl-diphosphatase activity
A7H1H_1844	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A7H1H_1845	COG0772	Belongs to the SEDS family
A7H1H_1847	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A7H1H_1855	COG0542	response to heat
A7H1H_1856	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
A7H1H_1857	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A7H1H_1860	COG2030	dehydratase
A7H1H_1864	COG0840	transmembrane signaling receptor activity
A7H1H_1865	COG1970	mechanosensitive ion channel activity
A7H1H_1866	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A7H1H_1870	COG2059	Chromate
A7H1H_1871	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A7H1H_1872	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7H1H_1874	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A7H1H_1875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A7H1H_1876	COG1157	protein secretion by the type III secretion system
A7H1H_1878	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A7H1H_1882	COG1677	Flagellar hook-basal body complex protein FliE
A7H1H_1884	COG0455	bacterial-type flagellum organization
A7H1H_1885	COG1419	protein localization to endoplasmic reticulum
A7H1H_1888	COG3951	Flagellar rod assembly protein muramidase FlgJ
A7H1H_1889	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A7H1H_1893	COG1749	Flagellar hook protein flgE
A7H1H_1894	COG4786	Flagellar basal body rod
A7H1H_1896	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A7H1H_1898	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A7H1H_1899	COG1766	The M ring may be actively involved in energy transduction
A7H1H_1900	COG1815	bacterial-type flagellum-dependent cell motility
A7H1H_1901	COG4786	Flagellar basal body rod
A7H1H_1903	COG0745	RESPONSE REGULATOR receiver
A7H1H_1907	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A7H1H_1909	COG0228	four-way junction DNA binding
A7H1H_1910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A7H1H_1911	COG0564	pseudouridine synthase activity
A7H1H_1912	COG1519	Transferase
A7H1H_1914	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A7H1H_1915	COG0752	glycyl-tRNA synthetase alpha subunit
A7H1H_1917	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A7H1H_1919	COG0826	peptidase U32
A7H1H_1920	COG0840	transmembrane signaling receptor activity
A7H1H_1921	COG0497	DNA recombination
A7H1H_1922	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A7H1H_1923	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A7H1H_1924	COG0049	tRNA binding
A7H1H_1925	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A7H1H_1927	COG2814	Major facilitator Superfamily
A7H1H_1928	COG4771	TonB-dependent receptor
A7H1H_1931	COG1116	anion transmembrane transporter activity
A7H1H_1932	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7H1H_1940	COG0512	Glutamine amidotransferase of anthranilate synthase
A7H1H_1941	COG1840	ABC-type Fe3 transport system, periplasmic component
A7H1H_1942	COG1178	ABC-type Fe3 transport system permease component
A7H1H_1945	COG4774	siderophore transport
A7H1H_1953	COG2183	response to ionizing radiation
A7H1H_1955	COG0251	oxidation-reduction process
A7H1H_1958	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7H1H_1960	COG0586	Pfam SNARE associated Golgi protein
A7H1H_1961	COG0335	large ribosomal subunit rRNA binding
A7H1H_1962	COG0336	Belongs to the RNA methyltransferase TrmD family
A7H1H_1964	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A7H1H_1965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A7H1H_1966	COG0356	it plays a direct role in the translocation of protons across the membrane
A7H1H_1968	COG4773	Receptor
A7H1H_1970	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A7H1H_1972	COG0157	Belongs to the NadC ModD family
A7H1H_1975	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
A7H1H_1977	COG0083	homoserine kinase activity
A7H1H_1979	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A7H1H_1980	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A7H1H_1981	COG0779	Required for maturation of 30S ribosomal subunits
A7H1H_1982	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7H1H_1982	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7H1H_1983	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A7H1H_1984	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7H1H_1985	COG1185	polyribonucleotide nucleotidyltransferase activity
A7H1H_1985	COG0539	negative regulation of cytoplasmic translation
A7H1H_1986	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A7H1H_1987	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A7H1H_1988	COG0072	phenylalanine-tRNA ligase activity
A7H1H_1988	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7H1H_1989	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A7H1H_1990	COG0537	adenosine 5'-monophosphoramidase activity
A7H1H_1991	COG0825	malonyl-CoA metabolic process
A7H1H_1992	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A7H1H_1993	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7H1H_1995	COG0602	queuosine metabolic process
A7H1H_1997	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A7H1H_1999	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A7H1H_2002	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A7H1H_2004	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A7H1H_2005	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A7H1H_2006	COG1074	ATP-dependent DNA helicase activity
A7H1H_2008	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A7H1H_2010	COG3328	transposase activity
A7H1H_2020	COG3278	Belongs to the heme-copper respiratory oxidase family
A7H1H_2021	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A7H1H_2022	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A7H1H_2023	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A7H1H_2024	COG0210	DNA helicase
A7H1H_2026	COG1242	4 iron, 4 sulfur cluster binding
A7H1H_2027	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A7H1H_2028	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A7H1H_2029	COG0492	ferredoxin-NADP+ reductase activity
A7H1H_2030	COG3118	belongs to the thioredoxin family
A7H1H_2031	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A7H1H_2036	COG0642	Histidine kinase
A7H1H_2037	COG0745	RESPONSE REGULATOR receiver
A7H1H_2039	COG0129	dihydroxy-acid dehydratase activity
A7H1H_2045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A7H1H_2048	COG0585	pseudouridine synthase activity
A7H1H_2051	COG0793	Belongs to the peptidase S41A family
A7H1H_2052	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A7H1H_2053	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A7H1H_2054	COG0047	phosphoribosylformylglycinamidine synthase activity
A7H1H_2056	COG0204	Acyl-transferase
A7H1H_2057	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A7H1H_2058	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A7H1H_2059	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A7H1H_2060	COG0018	arginyl-trna synthetase
A7H1H_2062	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A7H1H_2064	COG0126	phosphoglycerate kinase activity
A7H1H_2065	COG0149	triose-phosphate isomerase activity
A7H1H_2066	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A7H1H_2067	COG0019	diaminopimelate decarboxylase activity
A7H1H_2068	COG0077	Prephenate dehydratase
A7H1H_2068	COG1605	Chorismate mutase
A7H1H_2069	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A7H1H_2070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A7H1H_2072	COG0424	maF-like protein
A7H1H_2075	COG0791	NLP P60 protein
A7H1H_2078	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A7H1H_2079	COG1012	belongs to the aldehyde dehydrogenase family
A7H1H_2081	COG1704	LemA family
A7H1H_2084	COG0546	phosphoglycolate phosphatase activity
A7H1H_2085	COG0783	Belongs to the Dps family
A7H1H_2086	COG2814	Major facilitator Superfamily
A7H1H_2090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A7H1H_2095	COG1595	DNA-templated transcription, initiation
A7H1H_2099	COG2081	HI0933 family
A7H1H_2102	COG1959	2 iron, 2 sulfur cluster binding
A7H1H_2105	COG0175	sulfate reduction
A7H1H_2106	COG0175	sulfate reduction
A7H1H_2107	COG2895	sulfate adenylyltransferase (ATP) activity
A7H1H_2110	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A7H1H_2116	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A7H1H_2119	COG4232	protein-disulfide reductase activity
A7H1H_2120	COG0189	ligase activity
A7H1H_2123	COG2199	diguanylate cyclase activity
A7H1H_2123	COG2200	EAL domain
A7H1H_2123	COG3287	FIST C domain
A7H1H_2124	COG0688	phosphatidylethanolamine metabolic process
A7H1H_2126	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
A7H1H_2127	COG0443	Heat shock 70 kDa protein
A7H1H_2128	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A7H1H_2131	COG0101	tRNA pseudouridine synthase activity
A7H1H_2134	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A7H1H_2135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A7H1H_2136	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A7H1H_2139	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A7H1H_2140	COG0494	nUDIX hydrolase
A7H1H_2153	COG0445	tRNA wobble uridine modification
A7H1H_2157	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A7H1H_2158	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A7H1H_2159	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A7H1H_2161	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A7H1H_2166	COG1252	NADH dehydrogenase
A7H1H_2167	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
A7H1H_2169	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A7H1H_2170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A7H1H_2172	COG2814	Major facilitator Superfamily
A7H1H_2173	COG0659	secondary active sulfate transmembrane transporter activity
A7H1H_2177	COG1222	aaa ATPase
A7H1H_2179	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
A7H1H_2180	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A7H1H_2183	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A7H1H_2186	COG0148	phosphopyruvate hydratase activity
A7H1H_2187	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A7H1H_2189	COG1086	Polysaccharide biosynthesis protein
A7H1H_2190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A7H1H_2191	COG1083	cytidylyl-transferase
A7H1H_2193	COG2089	acid synthase
A7H1H_2196	COG1028	Short-chain dehydrogenase reductase Sdr
A7H1H_2200	COG1442	glycosyl transferase family 8
A7H1H_2200	COG1216	Glycosyl transferase, family 2
A7H1H_2201	COG1216	Glycosyl transferase, family 2
A7H1H_2216	COG0348	domain, Protein
A7H1H_2217	COG0504	CTP synthase activity
A7H1H_2218	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A7H1H_2222	COG0587	DNA-directed DNA polymerase activity
A7H1H_2223	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A7H1H_2226	COG3328	transposase activity
A7H1H_2228	COG0315	cyclic pyranopterin monophosphate synthase activity
A7H1H_2229	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A7H1H_2236	COG0670	Belongs to the BI1 family
A7H1H_2238	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A7H1H_2239	COG0233	cytoplasmic translational termination
A7H1H_2240	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A7H1H_2245	COG3022	response to hydroperoxide
A7H1H_2248	COG1408	metallophosphoesterase
A7H1H_2250	COG4771	TonB-dependent receptor
A7H1H_2251	COG1609	Transcriptional regulator
A7H1H_2251	COG2207	Transcriptional regulator
A7H1H_2252	COG0071	Belongs to the small heat shock protein (HSP20) family
A7H1H_2253	COG2703	oxygen carrier activity
A7H1H_2254	COG0840	transmembrane signaling receptor activity
A7H1H_2258	COG1305	Transglutaminase-like
A7H1H_2260	COG4208	sulfate ABC transporter
A7H1H_2261	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A7H1H_2263	COG3287	FIST C domain
A7H1H_2263	COG2200	EAL domain
A7H1H_2263	COG2199	diguanylate cyclase activity
A7H1H_2268	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A7H1H_2271	COG1116	anion transmembrane transporter activity
A7H1H_2272	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7H1H_2273	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7H1H_2274	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A7H1H_2279	COG2308	Evidence 4 Homologs of previously reported genes of
A7H1H_2280	COG1217	gtp-binding protein TYPA
A7H1H_2281	COG2391	methyltransferase activity
A7H1H_2282	COG0425	Belongs to the sulfur carrier protein TusA family
A7H1H_2283	COG3706	GGDEF domain
A7H1H_2291	COG0745	RESPONSE REGULATOR receiver
A7H1H_2292	COG2205	protein histidine kinase activity
A7H1H_2292	COG2770	Histidine kinase
A7H1H_2293	COG2226	methyltransferase
A7H1H_2294	COG2207	Transcriptional regulator
A7H1H_2295	COG3437	response regulator, receiver
A7H1H_2295	COG0784	Response regulator, receiver
A7H1H_2296	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A7H1H_2300	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group