locus-tag	class	description
ABED_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABED_0002	COG0592	DNA-directed DNA polymerase activity
ABED_0003	COG0187	DNA topoisomerase II activity
ABED_0004	COG0492	ferredoxin-NADP+ reductase activity
ABED_0005	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABED_0007	COG1238	metal cluster binding
ABED_0008	COG0500	methyltransferase
ABED_0009	COG3842	ATPase activity
ABED_0018	COG0564	pseudouridine synthase activity
ABED_0019	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABED_0020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABED_0021	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABED_0023	COG0824	Thioesterase
ABED_0027	COG0604	alcohol dehydrogenase
ABED_0028	COG1733	regulation of RNA biosynthetic process
ABED_0029	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ABED_0030	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABED_0033	COG1620	l-lactate permease
ABED_0034	COG0745	RESPONSE REGULATOR receiver
ABED_0035	COG3852	Histidine kinase
ABED_0036	COG1556	Lactate utilization protein
ABED_0037	COG1139	Iron-sulfur cluster binding protein
ABED_0038	COG0247	lactate metabolic process
ABED_0039	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABED_0040	COG0511	ligase activity, forming carbon-carbon bonds
ABED_0041	COG0439	Biotin carboxylase
ABED_0042	COG0513	Belongs to the DEAD box helicase family
ABED_0043	COG0306	phosphate transporter
ABED_0045	COG0367	asparagine synthase
ABED_0047	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ABED_0048	COG1981	membrane
ABED_0049	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABED_0049	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ABED_0050	COG1187	pseudouridine synthase activity
ABED_0051	COG0517	IMP dehydrogenase activity
ABED_0051	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ABED_0052	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ABED_0053	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABED_0054	COG0107	imidazoleglycerol-phosphate synthase activity
ABED_0057	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABED_0058	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABED_0059	COG0724	RNA recognition motif
ABED_0060	COG0745	RESPONSE REGULATOR receiver
ABED_0061	COG0642	Histidine kinase
ABED_0065	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABED_0072	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABED_0073	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ABED_0074	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ABED_0077	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABED_0078	COG0746	molybdenum cofactor guanylyltransferase activity
ABED_0079	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABED_0080	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ABED_0081	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABED_0082	COG0268	Binds directly to 16S ribosomal RNA
ABED_0083	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ABED_0085	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ABED_0086	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ABED_0087	COG0573	inorganic phosphate transmembrane transporter activity
ABED_0088	COG0581	inorganic phosphate transmembrane transporter activity
ABED_0089	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABED_0090	COG0704	Plays a role in the regulation of phosphate uptake
ABED_0092	COG0745	RESPONSE REGULATOR receiver
ABED_0093	COG5002	protein histidine kinase activity
ABED_0094	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABED_0095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABED_0097	COG0546	phosphoglycolate phosphatase activity
ABED_0101	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABED_0102	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABED_0103	COG1854	S-ribosylhomocysteine lyase activity
ABED_0106	COG1686	Belongs to the peptidase S11 family
ABED_0109	COG0646	methionine synthase
ABED_0109	COG1410	methionine synthase
ABED_0113	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABED_0113	COG0140	phosphoribosyl-ATP diphosphatase activity
ABED_0115	COG0489	protein tyrosine kinase activity
ABED_0116	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ABED_0118	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ABED_0118	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ABED_0120	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABED_0121	COG0505	Belongs to the CarA family
ABED_0123	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ABED_0124	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ABED_0125	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABED_0126	COG2353	YceI-like domain
ABED_0127	COG1846	Transcriptional regulator
ABED_0128	COG2353	YceI-like domain
ABED_0132	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABED_0133	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ABED_0134	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ABED_0135	COG0237	dephospho-CoA kinase activity
ABED_0136	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ABED_0137	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ABED_0138	COG0456	acetyltransferase
ABED_0143	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ABED_0144	COG0254	rRNA binding
ABED_0145	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ABED_0148	COG0436	Aminotransferase
ABED_0149	COG0460	homoserine dehydrogenase
ABED_0151	COG0575	Belongs to the CDS family
ABED_0152	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ABED_0155	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ABED_0156	COG0023	Translation Initiation Factor
ABED_0157	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABED_0157	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ABED_0158	COG1324	tolerance protein
ABED_0159	COG2022	thiamine diphosphate biosynthetic process
ABED_0163	COG0840	transmembrane signaling receptor activity
ABED_0167	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABED_0169	COG1346	cytolysis
ABED_0171	COG3766	membrane
ABED_0172	COG1301	dicarboxylic acid transport
ABED_0176	COG4589	Belongs to the CDS family
ABED_0178	COG0204	Acyl-transferase
ABED_0178	COG0318	PFAM AMP-dependent synthetase and ligase
ABED_0179	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ABED_0182	COG0666	response to abiotic stimulus
ABED_0184	COG0418	dihydroorotase activity
ABED_0186	COG1706	bacterial-type flagellum-dependent cell motility
ABED_0193	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ABED_0199	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABED_0200	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ABED_0201	COG0601	transmembrane transport
ABED_0202	COG0736	holo-[acyl-carrier-protein] synthase activity
ABED_0203	COG0786	glutamate:sodium symporter activity
ABED_0204	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABED_0206	COG0560	Phosphoserine phosphatase
ABED_0208	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ABED_0209	COG3248	Nucleoside-binding outer membrane protein
ABED_0210	COG1393	Belongs to the ArsC family
ABED_0211	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABED_0212	COG0343	queuine tRNA-ribosyltransferase activity
ABED_0214	COG0436	Aminotransferase
ABED_0218	COG2861	carbohydrate metabolic process
ABED_0219	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABED_0220	COG0557	exoribonuclease II activity
ABED_0221	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ABED_0223	COG0360	Binds together with S18 to 16S ribosomal RNA
ABED_0224	COG0629	single-stranded DNA binding
ABED_0225	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ABED_0227	COG0215	cysteine-tRNA ligase activity
ABED_0228	COG0195	Participates in both transcription termination and antitermination
ABED_0230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABED_0231	COG2121	Domain of unknown function (DUF374)
ABED_0234	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ABED_0236	COG0288	reversible hydration of carbon dioxide
ABED_0237	COG0156	8-amino-7-oxononanoate synthase activity
ABED_0238	COG0792	nuclease activity
ABED_0242	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABED_0244	COG0540	Belongs to the ATCase OTCase family
ABED_0245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ABED_0249	COG2824	Alkylphosphonate utilization operon protein PhnA
ABED_0250	COG1451	nucleotide metabolic process
ABED_0251	COG0730	response to heat
ABED_0257	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABED_0259	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ABED_0260	COG0372	Belongs to the citrate synthase family
ABED_0261	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABED_0262	COG2828	Protein conserved in bacteria
ABED_0264	COG1335	isochorismatase
ABED_0266	COG0181	hydroxymethylbilane synthase activity
ABED_0268	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ABED_0269	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABED_0270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABED_0271	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ABED_0272	COG0450	alkyl hydroperoxide reductase
ABED_0274	COG0105	UTP biosynthetic process
ABED_0276	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ABED_0277	COG0416	fatty acid biosynthetic process
ABED_0278	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABED_0282	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABED_0283	COG1053	succinate dehydrogenase
ABED_0285	COG1007	ATP synthesis coupled electron transport
ABED_0287	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABED_0288	COG0713	ATP synthesis coupled electron transport
ABED_0289	COG0839	Belongs to the complex I subunit 6 family
ABED_0290	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABED_0291	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABED_0292	COG1034	ATP synthesis coupled electron transport
ABED_0293	COG0372	Belongs to the citrate synthase family
ABED_0296	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABED_0296	COG0649	NAD binding
ABED_0297	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABED_0298	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABED_0299	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ABED_0300	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ABED_0301	COG3610	response to peptide
ABED_0302	COG2966	Psort location CytoplasmicMembrane, score
ABED_0305	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ABED_0310	COG4774	siderophore transport
ABED_0314	COG4771	TonB-dependent receptor
ABED_0316	COG1971	Probably functions as a manganese efflux pump
ABED_0320	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABED_0321	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABED_0321	COG1333	cytochrome c biogenesis protein
ABED_0322	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ABED_0323	COG3005	denitrification pathway
ABED_0325	COG2199	diguanylate cyclase activity
ABED_0325	COG3287	FIST C domain
ABED_0325	COG2200	EAL domain
ABED_0326	COG0840	transmembrane signaling receptor activity
ABED_0330	COG3043	anaerobic respiration
ABED_0331	COG0348	domain, Protein
ABED_0332	COG0437	4 iron, 4 sulfur cluster binding
ABED_0333	COG0243	molybdopterin cofactor binding
ABED_0335	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABED_0336	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABED_0338	COG4753	response regulator
ABED_0338	COG2207	Transcriptional regulator
ABED_0339	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABED_0340	COG1648	precorrin-2 dehydrogenase activity
ABED_0340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABED_0343	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABED_0344	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABED_0345	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ABED_0347	COG2404	hydrolase activity, acting on ester bonds
ABED_0348	COG1832	CoA-binding protein
ABED_0349	COG0642	Histidine kinase
ABED_0350	COG0745	RESPONSE REGULATOR receiver
ABED_0351	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABED_0352	COG0191	fructose-bisphosphate aldolase activity
ABED_0356	COG0811	peptide transport
ABED_0358	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ABED_0359	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABED_0361	COG0142	geranyltranstransferase activity
ABED_0362	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ABED_0363	COG0442	prolyl-tRNA aminoacylation
ABED_0364	COG0668	transmembrane transport
ABED_0365	COG0617	tRNA 3'-terminal CCA addition
ABED_0368	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ABED_0369	COG1862	Preprotein translocase
ABED_0370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABED_0371	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABED_0374	COG1360	Flagellar Motor Protein
ABED_0375	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ABED_0377	COG0495	leucyl-tRNA aminoacylation
ABED_0379	COG0285	dihydrofolate synthase activity
ABED_0385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABED_0389	COG0745	RESPONSE REGULATOR receiver
ABED_0390	COG0642	Histidine kinase
ABED_0391	COG2081	HI0933 family
ABED_0392	COG0840	transmembrane signaling receptor activity
ABED_0395	COG5002	protein histidine kinase activity
ABED_0396	COG1692	metallophosphoesterase
ABED_0399	COG2226	methyltransferase
ABED_0400	COG1570	exodeoxyribonuclease VII activity
ABED_0401	COG0835	chemotaxis
ABED_0402	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABED_0403	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ABED_0404	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ABED_0406	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ABED_0407	COG0459	protein refolding
ABED_0409	COG0745	RESPONSE REGULATOR receiver
ABED_0410	COG1408	metallophosphoesterase
ABED_0415	COG1136	(ABC) transporter
ABED_0419	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABED_0420	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABED_0421	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ABED_0422	COG0352	thiamine-phosphate diphosphorylase activity
ABED_0423	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ABED_0425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABED_0426	COG2264	protein methyltransferase activity
ABED_0427	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABED_0428	COG0784	Response regulator, receiver
ABED_0428	COG3437	response regulator, receiver
ABED_0431	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABED_0434	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABED_0436	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABED_0444	COG1132	(ABC) transporter
ABED_0448	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ABED_0449	COG1090	epimerase
ABED_0450	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABED_0454	COG0481	GTPase activity
ABED_0455	COG1937	Protein conserved in bacteria
ABED_0458	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABED_0460	COG0482	sulfurtransferase activity
ABED_0461	COG0482	sulfurtransferase activity
ABED_0462	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ABED_0463	COG0006	proline dipeptidase activity
ABED_0464	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ABED_0465	COG0402	S-adenosylhomocysteine deaminase activity
ABED_0466	COG0616	signal peptide processing
ABED_0468	COG0280	phosphate acetyltransferase
ABED_0469	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABED_0471	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABED_0472	COG2176	DNA-directed DNA polymerase activity
ABED_0478	COG2176	DNA-directed DNA polymerase activity
ABED_0480	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABED_0483	COG5002	protein histidine kinase activity
ABED_0484	COG1058	Belongs to the CinA family
ABED_0484	COG1546	Belongs to the CinA family
ABED_0485	COG0579	oxidoreductase
ABED_0486	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABED_0489	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABED_0493	COG0745	RESPONSE REGULATOR receiver
ABED_0494	COG4585	Histidine kinase
ABED_0497	COG0667	Aldo Keto reductase
ABED_0498	COG0306	phosphate transporter
ABED_0500	COG0840	transmembrane signaling receptor activity
ABED_0502	COG0840	transmembrane signaling receptor activity
ABED_0503	COG0824	Thioesterase
ABED_0505	COG0501	Belongs to the peptidase M48B family
ABED_0506	COG1322	Protein conserved in bacteria
ABED_0510	COG0037	tRNA processing
ABED_0514	COG0052	Belongs to the universal ribosomal protein uS2 family
ABED_0515	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ABED_0516	COG1136	(ABC) transporter
ABED_0518	COG0194	GDP metabolic process
ABED_0519	COG5002	protein histidine kinase activity
ABED_0519	COG5001	Diguanylate cyclase
ABED_0520	COG2217	Heavy metal translocating P-type atpase
ABED_0523	COG4608	Belongs to the ABC transporter superfamily
ABED_0524	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABED_0525	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ABED_0527	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ABED_0528	COG1121	(ABC) transporter
ABED_0529	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABED_0530	COG2996	Protein conserved in bacteria
ABED_0531	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ABED_0535	COG0210	DNA helicase
ABED_0536	COG0475	glutathione-regulated potassium exporter activity
ABED_0536	COG0569	domain protein
ABED_0537	COG0525	valine-tRNA ligase activity
ABED_0538	COG4895	conserved protein (DUF2196)
ABED_0540	COG2814	Major facilitator Superfamily
ABED_0541	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABED_0545	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ABED_0546	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABED_0547	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABED_0549	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABED_0555	COG0840	transmembrane signaling receptor activity
ABED_0556	COG0840	transmembrane signaling receptor activity
ABED_0561	COG0439	Biotin carboxylase
ABED_0562	COG2151	metal-sulfur cluster biosynthetic enzyme
ABED_0563	COG2166	iron-sulfur cluster assembly
ABED_0564	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ABED_0566	COG0396	ATPase activity
ABED_0567	COG0719	Fe-S assembly protein
ABED_0569	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ABED_0569	COG2906	2 iron, 2 sulfur cluster binding
ABED_0569	COG0822	iron-sulfur transferase activity
ABED_0570	COG2239	Acts as a magnesium transporter
ABED_0571	COG3706	GGDEF domain
ABED_0572	COG0165	Argininosuccinate lyase
ABED_0573	COG0784	Response regulator, receiver
ABED_0573	COG0835	chemotaxis
ABED_0574	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ABED_0575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABED_0577	COG0556	nucleotide-excision repair
ABED_0579	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABED_0583	COG0840	transmembrane signaling receptor activity
ABED_0587	COG4191	Histidine kinase
ABED_0588	COG0840	transmembrane signaling receptor activity
ABED_0592	COG0698	ribose 5-phosphate isomerase
ABED_0593	COG0681	Belongs to the peptidase S26 family
ABED_0594	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABED_0595	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ABED_0596	COG0193	aminoacyl-tRNA hydrolase activity
ABED_0599	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABED_0601	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ABED_0604	COG0528	UMP kinase activity
ABED_0606	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABED_0607	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ABED_0608	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ABED_0610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABED_0611	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ABED_0613	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ABED_0615	COG0305	Participates in initiation and elongation during chromosome replication
ABED_0618	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABED_0620	COG2089	acid synthase
ABED_0621	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ABED_0623	COG1083	cytidylyl-transferase
ABED_0624	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABED_0626	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABED_0630	COG1028	Short-chain dehydrogenase reductase Sdr
ABED_0633	COG0110	maltose O-acetyltransferase activity
ABED_0639	COG1086	Polysaccharide biosynthesis protein
ABED_0644	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABED_0645	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ABED_0646	COG1086	Polysaccharide biosynthesis protein
ABED_0648	COG1793	dna ligase
ABED_0649	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABED_0650	COG0133	tryptophan synthase activity
ABED_0652	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ABED_0654	COG0848	biopolymer transport protein
ABED_0658	COG0577	efflux transmembrane transporter activity
ABED_0658	COG1136	(ABC) transporter
ABED_0659	COG0577	efflux transmembrane transporter activity
ABED_0659	COG1136	(ABC) transporter
ABED_0668	COG0735	belongs to the Fur family
ABED_0670	COG0114	fumarate hydratase activity
ABED_0672	COG3920	Histidine kinase
ABED_0673	COG0784	Response regulator, receiver
ABED_0674	COG4774	siderophore transport
ABED_0675	COG3128	pkhd-type hydroxylase
ABED_0677	COG4771	TonB-dependent receptor
ABED_0681	COG1966	Carbon starvation protein
ABED_0682	COG0012	GTP binding
ABED_0686	COG3123	guanosine phosphorylase activity
ABED_0688	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ABED_0689	COG0585	pseudouridine synthase activity
ABED_0691	COG0840	transmembrane signaling receptor activity
ABED_0692	COG0632	four-way junction helicase activity
ABED_0693	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABED_0698	COG0051	transcription antitermination factor activity, RNA binding
ABED_0699	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ABED_0700	COG0088	Forms part of the polypeptide exit tunnel
ABED_0701	COG0089	rRNA binding
ABED_0702	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ABED_0703	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ABED_0704	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ABED_0705	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABED_0706	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ABED_0707	COG0255	Belongs to the universal ribosomal protein uL29 family
ABED_0708	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ABED_0709	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABED_0710	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ABED_0711	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ABED_0712	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ABED_0713	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ABED_0714	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABED_0715	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ABED_0716	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABED_0717	COG0200	Binds to the 23S rRNA
ABED_0718	COG0201	protein transport
ABED_0719	COG0024	Methionine aminopeptidase
ABED_0720	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABED_0721	COG1573	uracil-dna glycosylase
ABED_0723	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ABED_0725	COG1032	radical SAM domain protein
ABED_0727	COG0563	adenylate kinase activity
ABED_0731	COG1064	alcohol dehydrogenase
ABED_0732	COG1979	alcohol dehydrogenase
ABED_0733	COG0840	transmembrane signaling receptor activity
ABED_0734	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABED_0735	COG0322	excinuclease ABC activity
ABED_0736	COG0840	transmembrane signaling receptor activity
ABED_0737	COG0840	transmembrane signaling receptor activity
ABED_0738	COG0840	transmembrane signaling receptor activity
ABED_0739	COG0840	transmembrane signaling receptor activity
ABED_0748	COG3706	GGDEF domain
ABED_0749	COG0708	Exodeoxyribonuclease III
ABED_0753	COG3040	lipid binding
ABED_0756	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABED_0758	COG2200	EAL domain
ABED_0759	COG3279	Response regulator of the LytR AlgR family
ABED_0760	COG3275	phosphorelay sensor kinase activity
ABED_0761	COG1233	COG1233 Phytoene dehydrogenase and related
ABED_0762	COG0415	Belongs to the DNA photolyase family
ABED_0766	COG0166	Belongs to the GPI family
ABED_0770	COG0840	transmembrane signaling receptor activity
ABED_0771	COG1942	4-Oxalocrotonate Tautomerase
ABED_0772	COG0583	DNA-binding transcription factor activity
ABED_0773	COG0134	indole-3-glycerol-phosphate synthase activity
ABED_0775	COG0727	PFAM Uncharacterised protein family (UPF0153)
ABED_0776	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ABED_0778	COG0674	pyruvate-flavodoxin oxidoreductase activity
ABED_0778	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ABED_0779	COG1013	pyruvate-flavodoxin oxidoreductase activity
ABED_0781	COG2176	DNA-directed DNA polymerase activity
ABED_0782	COG0135	phosphoribosylanthranilate isomerase activity
ABED_0783	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABED_0787	COG1666	GTP binding
ABED_0789	COG2363	Small membrane protein
ABED_0790	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ABED_0793	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ABED_0809	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ABED_0817	COG3550	peptidyl-serine autophosphorylation
ABED_0819	COG0840	transmembrane signaling receptor activity
ABED_0820	COG0840	transmembrane signaling receptor activity
ABED_0821	COG0840	transmembrane signaling receptor activity
ABED_0823	COG0750	zinc metalloprotease
ABED_0824	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABED_0825	COG1028	Short-chain dehydrogenase reductase Sdr
ABED_0826	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABED_0828	COG0167	dihydroorotate dehydrogenase activity
ABED_0829	COG1132	(ABC) transporter
ABED_0830	COG0728	peptidoglycan biosynthetic process
ABED_0833	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ABED_0835	COG3340	Belongs to the peptidase S51 family
ABED_0836	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ABED_0837	COG3150	esterase
ABED_0838	COG1858	cytochrome C peroxidase
ABED_0841	COG0552	protein localization to endoplasmic reticulum
ABED_0842	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABED_0843	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ABED_0844	COG1418	mRNA catabolic process
ABED_0845	COG0742	ribosomal rna small subunit methyltransferase
ABED_0846	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABED_0847	COG0300	oxidoreductase activity
ABED_0851	COG3258	Cytochrome c
ABED_0853	COG0745	RESPONSE REGULATOR receiver
ABED_0854	COG0642	Histidine kinase
ABED_0855	COG0157	Belongs to the NadC ModD family
ABED_0857	COG1610	YqeY-like protein
ABED_0858	COG0488	(ABC) transporter
ABED_0860	COG0492	ferredoxin-NADP+ reductase activity
ABED_0861	COG0596	Alpha beta hydrolase
ABED_0864	COG0251	oxidation-reduction process
ABED_0869	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABED_0869	COG0519	Catalyzes the synthesis of GMP from XMP
ABED_0870	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ABED_0872	COG1451	nucleotide metabolic process
ABED_0873	COG0436	Aminotransferase
ABED_0874	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ABED_0881	COG1696	Membrane protein involved in D-alanine export
ABED_0883	COG2223	nitrite transmembrane transporter activity
ABED_0885	COG0310	cobalt ion transport
ABED_0890	COG3210	domain, Protein
ABED_0890	COG3210	domain, Protein
ABED_0898	COG0515	serine threonine protein kinase
ABED_0898	COG2815	serine threonine protein kinase
ABED_0900	COG0628	permease
ABED_0905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ABED_0907	COG0840	transmembrane signaling receptor activity
ABED_0908	COG0730	response to heat
ABED_0909	COG1045	serine acetyltransferase
ABED_0910	COG1166	arginine decarboxylase activity
ABED_0911	COG0124	histidyl-tRNA synthetase
ABED_0912	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABED_0913	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ABED_0914	COG0163	prenyltransferase activity
ABED_0916	COG0359	binds to the 23S rRNA
ABED_0917	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ABED_0918	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ABED_0920	COG0084	hydrolase, TatD family'
ABED_0922	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ABED_0923	COG0131	Imidazoleglycerol-phosphate dehydratase
ABED_0924	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ABED_0927	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ABED_0928	COG0456	acetyltransferase
ABED_0932	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ABED_0933	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABED_0938	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABED_0940	COG0784	Response regulator, receiver
ABED_0940	COG3437	response regulator, receiver
ABED_0942	COG0768	penicillin binding
ABED_0946	COG2884	Cell division ATP-binding protein ftsE
ABED_0947	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABED_0949	COG0564	pseudouridine synthase activity
ABED_0950	COG0772	Belongs to the SEDS family
ABED_0952	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABED_0953	COG3123	guanosine phosphorylase activity
ABED_0957	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABED_0958	COG0066	3-isopropylmalate dehydratase activity
ABED_0959	COG0473	3-isopropylmalate dehydrogenase activity
ABED_0962	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ABED_0963	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABED_0964	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ABED_0965	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABED_0966	COG0202	RNA polymerase activity
ABED_0967	COG0203	ribosomal protein L17
ABED_0968	COG0154	amidase activity
ABED_0969	COG0517	IMP dehydrogenase activity
ABED_0969	COG0516	GMP reductase activity
ABED_0979	COG0484	heat shock protein binding
ABED_0982	COG3290	protein histidine kinase activity
ABED_0983	COG0784	Response regulator, receiver
ABED_0983	COG2205	protein histidine kinase activity
ABED_0987	COG1119	ATPase activity
ABED_0994	COG1733	regulation of RNA biosynthetic process
ABED_0995	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABED_0997	COG2076	Multidrug Resistance protein
ABED_1000	COG1881	PFAM PEBP family protein
ABED_1001	COG0583	DNA-binding transcription factor activity
ABED_1002	COG2855	membrane
ABED_1008	COG1733	regulation of RNA biosynthetic process
ABED_1009	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABED_1013	COG0778	Nitroreductase
ABED_1015	COG0488	(ABC) transporter
ABED_1016	COG1607	acyl-coa hydrolase
ABED_1017	COG0840	transmembrane signaling receptor activity
ABED_1018	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABED_1019	COG0754	glutathionylspermidine amidase activity
ABED_1022	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ABED_1024	COG1496	oxidoreductase activity
ABED_1025	COG0280	phosphate acetyltransferase
ABED_1025	COG0281	malic enzyme
ABED_1026	COG0788	formyltetrahydrofolate deformylase activity
ABED_1027	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ABED_1032	COG0745	RESPONSE REGULATOR receiver
ABED_1034	COG0330	HflC and HflK could
ABED_1039	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ABED_1041	COG0546	phosphoglycolate phosphatase activity
ABED_1045	COG4206	TonB-dependent receptor
ABED_1047	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ABED_1048	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABED_1049	COG0475	glutathione-regulated potassium exporter activity
ABED_1050	COG0406	alpha-ribazole phosphatase activity
ABED_1051	COG1132	(ABC) transporter
ABED_1053	COG0745	RESPONSE REGULATOR receiver
ABED_1054	COG0642	Histidine kinase
ABED_1061	COG0513	Belongs to the DEAD box helicase family
ABED_1063	COG0745	RESPONSE REGULATOR receiver
ABED_1070	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ABED_1072	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABED_1073	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABED_1075	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABED_1076	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABED_1085	COG0243	molybdopterin cofactor binding
ABED_1088	COG1193	negative regulation of DNA recombination
ABED_1089	COG1253	flavin adenine dinucleotide binding
ABED_1091	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABED_1092	COG0004	ammonium transporteR
ABED_1097	COG0028	Belongs to the TPP enzyme family
ABED_1098	COG0440	acetolactate synthase activity
ABED_1099	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABED_1100	COG1674	ftsk spoiiie
ABED_1100	COG1196	nuclear chromosome segregation
ABED_1101	COG0745	RESPONSE REGULATOR receiver
ABED_1102	COG0642	Histidine kinase
ABED_1103	COG3012	SEC-C Motif Domain Protein
ABED_1105	COG1160	GTP binding
ABED_1106	COG0659	secondary active sulfate transmembrane transporter activity
ABED_1110	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ABED_1112	COG1185	polyribonucleotide nucleotidyltransferase activity
ABED_1114	COG0643	Histidine kinase
ABED_1114	COG2198	Histidine kinase
ABED_1115	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ABED_1116	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ABED_1117	COG2201	protein-glutamate methylesterase activity
ABED_1119	COG2223	nitrite transmembrane transporter activity
ABED_1120	COG0582	viral genome integration into host DNA
ABED_1124	COG0339	signal peptide processing
ABED_1125	COG2890	protein-(glutamine-N5) methyltransferase activity
ABED_1126	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABED_1127	COG0494	nUDIX hydrolase
ABED_1128	COG0527	aspartate kinase activity
ABED_1131	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ABED_1132	COG0287	Prephenate dehydrogenase
ABED_1133	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABED_1134	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ABED_1135	COG0612	Peptidase, M16
ABED_1136	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABED_1141	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ABED_1143	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABED_1143	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABED_1148	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ABED_1150	COG0751	glycine-tRNA ligase activity
ABED_1154	COG0357	Ribosomal RNA small subunit methyltransferase G
ABED_1155	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABED_1156	COG0113	porphobilinogen synthase activity
ABED_1157	COG0784	Response regulator, receiver
ABED_1157	COG4191	Histidine kinase
ABED_1158	COG0745	RESPONSE REGULATOR receiver
ABED_1161	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ABED_1161	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABED_1162	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABED_1163	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABED_1164	COG1663	tetraacyldisaccharide 4'-kinase activity
ABED_1166	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ABED_1171	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABED_1172	COG0805	protein transport
ABED_1173	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABED_1174	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABED_1177	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ABED_1181	COG2181	nitrate reductase activity
ABED_1181	COG0247	lactate metabolic process
ABED_1182	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ABED_1187	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ABED_1188	COG3287	FIST C domain
ABED_1188	COG2200	EAL domain
ABED_1188	COG2199	diguanylate cyclase activity
ABED_1189	COG1137	ATPase activity
ABED_1190	COG0802	atpase or kinase
ABED_1191	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABED_1194	COG0137	argininosuccinate synthase activity
ABED_1195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABED_1196	COG1696	Membrane protein involved in D-alanine export
ABED_1199	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABED_1201	COG0569	domain protein
ABED_1202	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ABED_1203	COG0745	RESPONSE REGULATOR receiver
ABED_1204	COG2205	protein histidine kinase activity
ABED_1207	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ABED_1208	COG0484	heat shock protein binding
ABED_1209	COG0133	tryptophan synthase activity
ABED_1213	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABED_1215	COG2199	diguanylate cyclase activity
ABED_1216	COG0500	methyltransferase
ABED_1218	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABED_1218	COG1333	cytochrome c biogenesis protein
ABED_1219	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABED_1221	COG0840	transmembrane signaling receptor activity
ABED_1223	COG0653	protein targeting
ABED_1224	COG4591	ABC-type transport system involved in lipoprotein release permease component
ABED_1226	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ABED_1228	COG0039	L-malate dehydrogenase activity
ABED_1233	COG0275	rRNA processing
ABED_1235	COG0776	regulation of translation
ABED_1259	COG2026	Addiction module toxin, RelE StbE family
ABED_1261	COG4974	Belongs to the 'phage' integrase family
ABED_1262	COG1959	2 iron, 2 sulfur cluster binding
ABED_1265	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ABED_1265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABED_1267	COG2201	protein-glutamate methylesterase activity
ABED_1270	COG0484	heat shock protein binding
ABED_1271	COG0789	Transcriptional regulator
ABED_1272	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABED_1273	COG1131	(ABC) transporter
ABED_1274	COG0842	Transport permease protein
ABED_1275	COG0842	Transport permease protein
ABED_1276	COG0861	Integral membrane protein TerC family
ABED_1277	COG1114	Component of the transport system for branched-chain amino acids
ABED_1280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABED_1282	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ABED_1284	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABED_1285	COG4773	Receptor
ABED_1287	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABED_1296	COG0488	(ABC) transporter
ABED_1298	COG2171	N-acyltransferase activity
ABED_1299	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABED_1301	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABED_1307	COG0309	Hydrogenase expression formation protein (HypE)
ABED_1309	COG2084	Dehydrogenase
ABED_1311	COG0409	Hydrogenase expression formation protein
ABED_1312	COG0298	carbon dioxide binding
ABED_1313	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ABED_1315	COG0840	transmembrane signaling receptor activity
ABED_1317	COG2081	HI0933 family
ABED_1318	COG2354	Protein conserved in bacteria
ABED_1321	COG2814	Major facilitator Superfamily
ABED_1323	COG0301	tRNA thio-modification
ABED_1323	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABED_1327	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ABED_1328	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ABED_1329	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ABED_1330	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ABED_1331	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ABED_1332	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ABED_1335	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ABED_1338	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ABED_1339	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ABED_1343	COG1049	propionate catabolic process, 2-methylcitrate cycle
ABED_1345	COG2203	Gaf domain
ABED_1345	COG3706	GGDEF domain
ABED_1345	COG4251	negative regulation of phosphorylation
ABED_1345	COG5001	Diguanylate cyclase
ABED_1346	COG0217	transcriptional regulatory protein
ABED_1347	COG2853	Lipoprotein
ABED_1350	COG1611	Belongs to the LOG family
ABED_1351	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABED_1354	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ABED_1358	COG4774	siderophore transport
ABED_1364	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABED_1369	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABED_1370	COG2258	MOSC domain
ABED_1371	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABED_1372	COG0095	Lipoate-protein ligase
ABED_1373	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ABED_1374	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABED_1375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABED_1376	COG1492	cobalamin metabolic process
ABED_1380	COG0513	Belongs to the DEAD box helicase family
ABED_1381	COG1944	ATP diphosphatase activity
ABED_1384	COG0840	transmembrane signaling receptor activity
ABED_1385	COG0328	RNA-DNA hybrid ribonuclease activity
ABED_1386	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABED_1391	COG1104	cysteine desulfurase activity
ABED_1392	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ABED_1394	COG0437	4 iron, 4 sulfur cluster binding
ABED_1395	COG3383	formate dehydrogenase (NAD+) activity
ABED_1396	COG0243	molybdopterin cofactor binding
ABED_1396	COG3383	formate dehydrogenase (NAD+) activity
ABED_1406	COG1305	Transglutaminase-like
ABED_1408	COG0437	4 iron, 4 sulfur cluster binding
ABED_1409	COG0243	molybdopterin cofactor binding
ABED_1409	COG3383	formate dehydrogenase (NAD+) activity
ABED_1411	COG0709	Synthesizes selenophosphate from selenide and ATP
ABED_1421	COG1921	L-seryl-tRNASec selenium transferase activity
ABED_1430	COG1078	dGTPase activity
ABED_1431	COG5002	protein histidine kinase activity
ABED_1431	COG5001	Diguanylate cyclase
ABED_1432	COG0259	pyridoxamine-phosphate oxidase activity
ABED_1434	COG0513	Belongs to the DEAD box helicase family
ABED_1438	COG0326	Molecular chaperone. Has ATPase activity
ABED_1439	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ABED_1443	COG2995	paraquat-inducible protein a
ABED_1446	COG5002	protein histidine kinase activity
ABED_1446	COG5001	Diguanylate cyclase
ABED_1452	COG4335	DNA alkylation repair
ABED_1453	COG2329	Antibiotic biosynthesis monooxygenase
ABED_1457	COG4774	siderophore transport
ABED_1459	COG1595	DNA-templated transcription, initiation
ABED_1460	COG0010	Belongs to the arginase family
ABED_1461	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABED_1463	COG0519	Catalyzes the synthesis of GMP from XMP
ABED_1464	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABED_1465	COG0668	transmembrane transport
ABED_1466	COG1227	inorganic diphosphatase activity
ABED_1469	COG1027	Aspartate ammonia-lyase
ABED_1470	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABED_1471	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ABED_1472	COG1047	Peptidyl-prolyl cis-trans
ABED_1475	COG0823	Involved in the tonB-independent uptake of proteins
ABED_1477	COG0848	biopolymer transport protein
ABED_1478	COG0811	peptide transport
ABED_1479	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABED_1480	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABED_1481	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABED_1482	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ABED_1483	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABED_1484	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABED_1486	COG1475	DNA binding
ABED_1487	COG1192	Involved in chromosome partitioning
ABED_1490	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABED_1491	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABED_1492	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABED_1493	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ABED_1494	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABED_1495	COG0358	DNA primase activity
ABED_1497	COG0571	ribonuclease III activity
ABED_1498	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ABED_1500	COG0501	Belongs to the peptidase M48B family
ABED_1504	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABED_1506	COG0706	membrane insertase activity
ABED_1507	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ABED_1508	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ABED_1509	COG0542	response to heat
ABED_1510	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABED_1512	COG2326	polyphosphate kinase activity
ABED_1514	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABED_1515	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABED_1516	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABED_1521	COG0138	bifunctional purine biosynthesis protein purh
ABED_1522	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABED_1524	COG0739	heme binding
ABED_1525	COG0302	gtp cyclohydrolase
ABED_1526	COG0598	Magnesium transport protein CorA
ABED_1531	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABED_1533	COG0606	chelatase, subunit chli
ABED_1540	COG0210	DNA helicase
ABED_1550	COG0606	chelatase, subunit chli
ABED_1551	COG0840	transmembrane signaling receptor activity
ABED_1554	COG0242	peptide deformylase activity
ABED_1555	COG0740	serine-type endopeptidase activity
ABED_1556	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABED_1564	COG0626	cystathionine gamma-synthase activity
ABED_1567	COG0840	transmembrane signaling receptor activity
ABED_1569	COG0784	Response regulator, receiver
ABED_1569	COG3437	response regulator, receiver
ABED_1570	COG0840	transmembrane signaling receptor activity
ABED_1571	COG2205	protein histidine kinase activity
ABED_1577	COG0745	RESPONSE REGULATOR receiver
ABED_1579	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ABED_1582	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ABED_1583	COG1858	cytochrome C peroxidase
ABED_1589	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABED_1593	COG0351	phosphomethylpyrimidine kinase
ABED_1594	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ABED_1597	COG0348	domain, Protein
ABED_1599	COG4753	response regulator
ABED_1599	COG2207	Transcriptional regulator
ABED_1602	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABED_1606	COG0716	FMN binding
ABED_1609	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ABED_1610	COG0159	tryptophan synthase activity
ABED_1611	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ABED_1612	COG2255	four-way junction helicase activity
ABED_1613	COG0628	permease
ABED_1615	COG0731	radical SAM domain protein
ABED_1616	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ABED_1618	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ABED_1621	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ABED_1623	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ABED_1627	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ABED_1627	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ABED_1628	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ABED_1629	COG1368	sulfuric ester hydrolase activity
ABED_1630	COG0859	PFAM glycosyl transferase family 9
ABED_1632	COG0859	PFAM glycosyl transferase family 9
ABED_1633	COG0463	Glycosyl transferase, family 2
ABED_1636	COG0438	transferase activity, transferring glycosyl groups
ABED_1640	COG1696	Membrane protein involved in D-alanine export
ABED_1642	COG1696	Membrane protein involved in D-alanine export
ABED_1644	COG1696	Membrane protein involved in D-alanine export
ABED_1655	COG0859	PFAM glycosyl transferase family 9
ABED_1657	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABED_1659	COG0493	'glutamate synthase
ABED_1660	COG0070	glutamate synthase
ABED_1660	COG0069	glutamate synthase activity
ABED_1660	COG0067	glutamate synthase
ABED_1663	COG0840	transmembrane signaling receptor activity
ABED_1664	COG0840	transmembrane signaling receptor activity
ABED_1667	COG1739	Uncharacterized protein family UPF0029
ABED_1669	COG0196	riboflavin kinase activity
ABED_1670	COG2226	methyltransferase
ABED_1671	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABED_1673	COG0277	FAD linked oxidase domain protein
ABED_1674	COG1295	ribonuclease BN
ABED_1676	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABED_1678	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ABED_1679	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABED_1680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABED_1681	COG0284	orotidine-5'-phosphate decarboxylase activity
ABED_1684	COG1918	ferrous iron import across plasma membrane
ABED_1685	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ABED_1685	COG1918	ferrous iron import across plasma membrane
ABED_1690	COG2217	Heavy metal translocating P-type atpase
ABED_1692	COG4773	Receptor
ABED_1694	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABED_1697	COG1278	Cold shock
ABED_1699	COG2207	Transcriptional regulator
ABED_1699	COG4753	response regulator
ABED_1700	COG3852	Histidine kinase
ABED_1701	COG3135	benzoate transporter
ABED_1704	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ABED_1705	COG0085	RNA polymerase activity
ABED_1706	COG0222	ribosome binding
ABED_1707	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ABED_1708	COG0081	regulation of translation
ABED_1709	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ABED_1710	COG0250	Participates in transcription elongation, termination and antitermination
ABED_1712	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ABED_1713	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABED_1715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABED_1716	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ABED_1717	COG0444	Belongs to the ABC transporter superfamily
ABED_1718	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ABED_1719	COG0174	glutamine synthetase
ABED_1721	COG0314	molybdopterin synthase activity
ABED_1723	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ABED_1724	COG1968	undecaprenyl-diphosphatase activity
ABED_1725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ABED_1726	COG0772	Belongs to the SEDS family
ABED_1728	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABED_1730	COG0542	response to heat
ABED_1731	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ABED_1732	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ABED_1735	COG2030	dehydratase
ABED_1739	COG0840	transmembrane signaling receptor activity
ABED_1740	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABED_1744	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABED_1745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABED_1747	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABED_1748	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABED_1749	COG1157	protein secretion by the type III secretion system
ABED_1751	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABED_1755	COG1677	Flagellar hook-basal body complex protein FliE
ABED_1757	COG0455	bacterial-type flagellum organization
ABED_1758	COG1419	protein localization to endoplasmic reticulum
ABED_1761	COG3951	Flagellar rod assembly protein muramidase FlgJ
ABED_1766	COG1749	Flagellar hook protein flgE
ABED_1769	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABED_1771	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABED_1772	COG1766	The M ring may be actively involved in energy transduction
ABED_1773	COG1815	bacterial-type flagellum-dependent cell motility
ABED_1774	COG4786	Flagellar basal body rod
ABED_1776	COG0745	RESPONSE REGULATOR receiver
ABED_1777	COG4786	Flagellar basal body rod
ABED_1780	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABED_1782	COG0228	four-way junction DNA binding
ABED_1783	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABED_1784	COG0564	pseudouridine synthase activity
ABED_1785	COG1519	Transferase
ABED_1787	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABED_1788	COG0752	glycyl-tRNA synthetase alpha subunit
ABED_1790	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABED_1792	COG0826	peptidase U32
ABED_1793	COG0840	transmembrane signaling receptor activity
ABED_1794	COG0497	DNA recombination
ABED_1795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABED_1796	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABED_1797	COG0049	tRNA binding
ABED_1798	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABED_1800	COG2814	Major facilitator Superfamily
ABED_1801	COG4771	TonB-dependent receptor
ABED_1804	COG1116	anion transmembrane transporter activity
ABED_1805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABED_1808	COG0512	Glutamine amidotransferase of anthranilate synthase
ABED_1809	COG1309	transcriptional regulator
ABED_1810	COG4221	oxidoreductase activity
ABED_1812	COG1840	ABC-type Fe3 transport system, periplasmic component
ABED_1813	COG1178	ABC-type Fe3 transport system permease component
ABED_1816	COG4774	siderophore transport
ABED_1824	COG2183	response to ionizing radiation
ABED_1826	COG0251	oxidation-reduction process
ABED_1829	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABED_1831	COG0586	Pfam SNARE associated Golgi protein
ABED_1832	COG0335	large ribosomal subunit rRNA binding
ABED_1833	COG0336	Belongs to the RNA methyltransferase TrmD family
ABED_1835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ABED_1836	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABED_1837	COG0356	it plays a direct role in the translocation of protons across the membrane
ABED_1839	COG4773	Receptor
ABED_1841	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ABED_1843	COG0157	Belongs to the NadC ModD family
ABED_1846	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ABED_1848	COG0083	homoserine kinase activity
ABED_1850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABED_1851	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ABED_1852	COG0779	Required for maturation of 30S ribosomal subunits
ABED_1853	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABED_1853	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABED_1854	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABED_1855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABED_1856	COG1185	polyribonucleotide nucleotidyltransferase activity
ABED_1856	COG0539	negative regulation of cytoplasmic translation
ABED_1857	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ABED_1858	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABED_1859	COG0072	phenylalanine-tRNA ligase activity
ABED_1859	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABED_1860	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ABED_1861	COG0537	adenosine 5'-monophosphoramidase activity
ABED_1862	COG0825	malonyl-CoA metabolic process
ABED_1863	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABED_1864	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABED_1866	COG0602	queuosine metabolic process
ABED_1868	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABED_1870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABED_1872	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ABED_1874	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ABED_1875	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABED_1876	COG1074	ATP-dependent DNA helicase activity
ABED_1878	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ABED_1887	COG3278	Belongs to the heme-copper respiratory oxidase family
ABED_1888	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ABED_1889	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ABED_1890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABED_1893	COG1242	4 iron, 4 sulfur cluster binding
ABED_1894	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ABED_1895	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ABED_1896	COG0492	ferredoxin-NADP+ reductase activity
ABED_1897	COG3118	belongs to the thioredoxin family
ABED_1898	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABED_1903	COG0642	Histidine kinase
ABED_1904	COG0745	RESPONSE REGULATOR receiver
ABED_1906	COG0129	dihydroxy-acid dehydratase activity
ABED_1909	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABED_1912	COG0585	pseudouridine synthase activity
ABED_1915	COG0793	Belongs to the peptidase S41A family
ABED_1916	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ABED_1917	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABED_1918	COG0047	phosphoribosylformylglycinamidine synthase activity
ABED_1920	COG0204	Acyl-transferase
ABED_1921	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABED_1922	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABED_1923	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABED_1924	COG0018	arginyl-trna synthetase
ABED_1926	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ABED_1928	COG0126	phosphoglycerate kinase activity
ABED_1929	COG0149	triose-phosphate isomerase activity
ABED_1930	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ABED_1931	COG0019	diaminopimelate decarboxylase activity
ABED_1932	COG0077	Prephenate dehydratase
ABED_1932	COG1605	Chorismate mutase
ABED_1933	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABED_1934	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ABED_1936	COG0424	maF-like protein
ABED_1939	COG0791	NLP P60 protein
ABED_1942	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ABED_1943	COG1012	belongs to the aldehyde dehydrogenase family
ABED_1945	COG1704	LemA family
ABED_1948	COG0546	phosphoglycolate phosphatase activity
ABED_1949	COG0783	Belongs to the Dps family
ABED_1952	COG2814	Major facilitator Superfamily
ABED_1955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABED_1956	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABED_1960	COG1595	DNA-templated transcription, initiation
ABED_1962	COG2081	HI0933 family
ABED_1965	COG1959	2 iron, 2 sulfur cluster binding
ABED_1968	COG0175	sulfate reduction
ABED_1969	COG0175	sulfate reduction
ABED_1970	COG2895	sulfate adenylyltransferase (ATP) activity
ABED_1973	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABED_1979	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ABED_1982	COG4232	protein-disulfide reductase activity
ABED_1983	COG0189	ligase activity
ABED_1986	COG2199	diguanylate cyclase activity
ABED_1986	COG3287	FIST C domain
ABED_1986	COG2200	EAL domain
ABED_1987	COG0688	phosphatidylethanolamine metabolic process
ABED_1989	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ABED_1990	COG0443	Heat shock 70 kDa protein
ABED_1991	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ABED_1994	COG0101	tRNA pseudouridine synthase activity
ABED_1997	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABED_1998	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABED_1999	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABED_2002	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABED_2003	COG0494	nUDIX hydrolase
ABED_2006	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABED_2020	COG0445	tRNA wobble uridine modification
ABED_2024	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ABED_2025	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABED_2026	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ABED_2027	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABED_2028	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ABED_2030	COG1252	NADH dehydrogenase
ABED_2031	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ABED_2033	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABED_2036	COG2814	Major facilitator Superfamily
ABED_2037	COG0659	secondary active sulfate transmembrane transporter activity
ABED_2041	COG1222	aaa ATPase
ABED_2043	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ABED_2044	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ABED_2047	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ABED_2050	COG0148	phosphopyruvate hydratase activity
ABED_2051	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABED_2053	COG1086	Polysaccharide biosynthesis protein
ABED_2054	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABED_2055	COG1083	cytidylyl-transferase
ABED_2056	COG2089	acid synthase
ABED_2060	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ABED_2064	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABED_2066	COG0348	domain, Protein
ABED_2067	COG0504	CTP synthase activity
ABED_2068	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABED_2073	COG0587	DNA-directed DNA polymerase activity
ABED_2074	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ABED_2077	COG0315	cyclic pyranopterin monophosphate synthase activity
ABED_2078	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABED_2079	COG0670	Belongs to the BI1 family
ABED_2080	COG0352	thiamine-phosphate diphosphorylase activity
ABED_2082	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABED_2083	COG0233	cytoplasmic translational termination
ABED_2084	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABED_2094	COG3022	response to hydroperoxide
ABED_2097	COG3022	response to hydroperoxide
ABED_2100	COG1408	metallophosphoesterase
ABED_2101	COG0071	Belongs to the small heat shock protein (HSP20) family
ABED_2102	COG2703	oxygen carrier activity
ABED_2106	COG2308	Evidence 4 Homologs of previously reported genes of
ABED_2107	COG1305	Transglutaminase-like
ABED_2109	COG4208	sulfate ABC transporter
ABED_2110	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ABED_2112	COG2199	diguanylate cyclase activity
ABED_2112	COG3287	FIST C domain
ABED_2112	COG2200	EAL domain
ABED_2115	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ABED_2117	COG1116	anion transmembrane transporter activity
ABED_2119	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABED_2120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABED_2122	COG1116	anion transmembrane transporter activity
ABED_2123	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABED_2124	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABED_2125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABED_2130	COG2308	Evidence 4 Homologs of previously reported genes of
ABED_2131	COG1217	gtp-binding protein TYPA
ABED_2132	COG2391	methyltransferase activity
ABED_2133	COG0425	Belongs to the sulfur carrier protein TusA family
ABED_2140	COG3706	GGDEF domain
ABED_2149	COG0745	RESPONSE REGULATOR receiver
ABED_2150	COG0642	Histidine kinase
ABED_2151	COG2226	methyltransferase
ABED_2152	COG2207	Transcriptional regulator
ABED_2153	COG0784	Response regulator, receiver
ABED_2153	COG3437	response regulator, receiver
ABED_2154	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ABED_2158	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group