locus-tag	class	description
Abu_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Abu_0002	COG0592	DNA-directed DNA polymerase activity
Abu_0003	COG0187	DNA topoisomerase II activity
Abu_0004	COG0492	ferredoxin-NADP+ reductase activity
Abu_0005	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Abu_0007	COG1238	metal cluster binding
Abu_0008	COG0500	methyltransferase
Abu_0009	COG3842	ATPase activity
Abu_0018	COG0564	pseudouridine synthase activity
Abu_0019	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Abu_0020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Abu_0021	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Abu_0027	COG0604	alcohol dehydrogenase
Abu_0028	COG1733	regulation of RNA biosynthetic process
Abu_0029	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Abu_0030	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Abu_0033	COG1620	l-lactate permease
Abu_0034	COG0745	RESPONSE REGULATOR receiver
Abu_0035	COG3852	Histidine kinase
Abu_0036	COG1556	Lactate utilization protein
Abu_0037	COG1139	Iron-sulfur cluster binding protein
Abu_0038	COG0247	lactate metabolic process
Abu_0039	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Abu_0040	COG0511	ligase activity, forming carbon-carbon bonds
Abu_0041	COG0439	Biotin carboxylase
Abu_0042	COG0513	Belongs to the DEAD box helicase family
Abu_0043	COG0306	phosphate transporter
Abu_0045	COG0367	asparagine synthase
Abu_0047	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Abu_0048	COG1981	membrane
Abu_0049	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Abu_0049	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Abu_0050	COG1187	pseudouridine synthase activity
Abu_0051	COG0517	IMP dehydrogenase activity
Abu_0051	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Abu_0052	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Abu_0053	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Abu_0054	COG0107	imidazoleglycerol-phosphate synthase activity
Abu_0057	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Abu_0058	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Abu_0059	COG0724	RNA recognition motif
Abu_0060	COG0745	RESPONSE REGULATOR receiver
Abu_0061	COG0642	Histidine kinase
Abu_0072	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Abu_0073	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Abu_0074	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Abu_0077	COG0446	pyridine nucleotide-disulphide oxidoreductase
Abu_0078	COG0746	molybdenum cofactor guanylyltransferase activity
Abu_0079	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Abu_0080	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Abu_0081	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Abu_0082	COG0268	Binds directly to 16S ribosomal RNA
Abu_0083	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Abu_0085	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Abu_0086	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Abu_0087	COG0573	inorganic phosphate transmembrane transporter activity
Abu_0088	COG0581	inorganic phosphate transmembrane transporter activity
Abu_0089	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Abu_0090	COG0704	Plays a role in the regulation of phosphate uptake
Abu_0092	COG0745	RESPONSE REGULATOR receiver
Abu_0093	COG5002	protein histidine kinase activity
Abu_0094	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Abu_0095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Abu_0097	COG0546	phosphoglycolate phosphatase activity
Abu_0103	COG0288	reversible hydration of carbon dioxide
Abu_0107	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Abu_0108	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Abu_0111	COG1854	S-ribosylhomocysteine lyase activity
Abu_0114	COG1686	Belongs to the peptidase S11 family
Abu_0117	COG1410	methionine synthase
Abu_0117	COG0646	methionine synthase
Abu_0121	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Abu_0121	COG0140	phosphoribosyl-ATP diphosphatase activity
Abu_0123	COG0489	protein tyrosine kinase activity
Abu_0124	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Abu_0126	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Abu_0126	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Abu_0128	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Abu_0130	COG0505	Belongs to the CarA family
Abu_0132	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Abu_0133	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Abu_0134	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Abu_0135	COG2353	YceI-like domain
Abu_0136	COG1846	Transcriptional regulator
Abu_0137	COG2353	YceI-like domain
Abu_0140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Abu_0141	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Abu_0142	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Abu_0143	COG0237	dephospho-CoA kinase activity
Abu_0144	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Abu_0145	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Abu_0146	COG0456	acetyltransferase
Abu_0152	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Abu_0153	COG0254	rRNA binding
Abu_0154	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Abu_0157	COG0436	Aminotransferase
Abu_0158	COG0460	homoserine dehydrogenase
Abu_0160	COG0575	Belongs to the CDS family
Abu_0161	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Abu_0164	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Abu_0165	COG0023	Translation Initiation Factor
Abu_0166	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Abu_0166	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Abu_0167	COG1324	tolerance protein
Abu_0168	COG2022	thiamine diphosphate biosynthetic process
Abu_0182	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Abu_0184	COG1346	cytolysis
Abu_0186	COG3766	membrane
Abu_0187	COG1301	dicarboxylic acid transport
Abu_0191	COG4589	Belongs to the CDS family
Abu_0193	COG0318	PFAM AMP-dependent synthetase and ligase
Abu_0193	COG0204	Acyl-transferase
Abu_0194	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Abu_0197	COG0666	response to abiotic stimulus
Abu_0199	COG0418	dihydroorotase activity
Abu_0201	COG1706	bacterial-type flagellum-dependent cell motility
Abu_0208	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Abu_0214	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Abu_0215	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Abu_0216	COG0601	transmembrane transport
Abu_0217	COG0736	holo-[acyl-carrier-protein] synthase activity
Abu_0218	COG0786	glutamate:sodium symporter activity
Abu_0219	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Abu_0221	COG0560	Phosphoserine phosphatase
Abu_0223	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Abu_0224	COG3248	Nucleoside-binding outer membrane protein
Abu_0228	COG1393	Belongs to the ArsC family
Abu_0229	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Abu_0230	COG0343	queuine tRNA-ribosyltransferase activity
Abu_0232	COG0436	Aminotransferase
Abu_0236	COG2861	carbohydrate metabolic process
Abu_0237	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Abu_0238	COG0557	exoribonuclease II activity
Abu_0239	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Abu_0241	COG0360	Binds together with S18 to 16S ribosomal RNA
Abu_0242	COG0629	single-stranded DNA binding
Abu_0243	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Abu_0245	COG0215	cysteine-tRNA ligase activity
Abu_0246	COG0195	Participates in both transcription termination and antitermination
Abu_0248	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Abu_0249	COG2121	Domain of unknown function (DUF374)
Abu_0251	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Abu_0253	COG0288	reversible hydration of carbon dioxide
Abu_0254	COG0156	8-amino-7-oxononanoate synthase activity
Abu_0255	COG0792	nuclease activity
Abu_0259	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Abu_0261	COG0540	Belongs to the ATCase OTCase family
Abu_0262	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Abu_0265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Abu_0266	COG2824	Alkylphosphonate utilization operon protein PhnA
Abu_0267	COG1451	nucleotide metabolic process
Abu_0268	COG0730	response to heat
Abu_0274	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Abu_0276	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Abu_0277	COG0372	Belongs to the citrate synthase family
Abu_0278	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Abu_0279	COG2828	Protein conserved in bacteria
Abu_0283	COG0181	hydroxymethylbilane synthase activity
Abu_0285	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Abu_0286	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Abu_0287	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Abu_0288	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Abu_0289	COG0450	alkyl hydroperoxide reductase
Abu_0291	COG0105	UTP biosynthetic process
Abu_0293	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Abu_0294	COG0416	fatty acid biosynthetic process
Abu_0295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Abu_0299	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Abu_0300	COG1053	succinate dehydrogenase
Abu_0302	COG1007	ATP synthesis coupled electron transport
Abu_0304	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Abu_0305	COG0713	ATP synthesis coupled electron transport
Abu_0306	COG0839	Belongs to the complex I subunit 6 family
Abu_0307	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Abu_0308	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Abu_0309	COG1034	ATP synthesis coupled electron transport
Abu_0310	COG0372	Belongs to the citrate synthase family
Abu_0313	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Abu_0313	COG0649	NAD binding
Abu_0314	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Abu_0315	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Abu_0316	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Abu_0317	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Abu_0318	COG3610	response to peptide
Abu_0319	COG2966	Psort location CytoplasmicMembrane, score
Abu_0322	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Abu_0328	COG4774	siderophore transport
Abu_0333	COG4771	TonB-dependent receptor
Abu_0335	COG1971	Probably functions as a manganese efflux pump
Abu_0338	COG1132	(ABC) transporter
Abu_0339	COG2375	cellular response to nickel ion
Abu_0339	COG1132	(ABC) transporter
Abu_0340	COG4771	TonB-dependent receptor
Abu_0345	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Abu_0346	COG1333	cytochrome c biogenesis protein
Abu_0346	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Abu_0347	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
Abu_0348	COG3005	denitrification pathway
Abu_0350	COG3287	FIST C domain
Abu_0350	COG2200	EAL domain
Abu_0350	COG2199	diguanylate cyclase activity
Abu_0351	COG0840	transmembrane signaling receptor activity
Abu_0355	COG3043	anaerobic respiration
Abu_0356	COG0348	domain, Protein
Abu_0357	COG0437	4 iron, 4 sulfur cluster binding
Abu_0358	COG0243	molybdopterin cofactor binding
Abu_0360	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Abu_0361	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Abu_0363	COG2204	response regulator
Abu_0364	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Abu_0365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Abu_0365	COG1648	precorrin-2 dehydrogenase activity
Abu_0368	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Abu_0369	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Abu_0370	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Abu_0372	COG2404	hydrolase activity, acting on ester bonds
Abu_0373	COG1832	CoA-binding protein
Abu_0374	COG0642	Histidine kinase
Abu_0375	COG0745	RESPONSE REGULATOR receiver
Abu_0376	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Abu_0377	COG0191	fructose-bisphosphate aldolase activity
Abu_0381	COG0811	peptide transport
Abu_0383	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Abu_0384	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Abu_0386	COG0142	geranyltranstransferase activity
Abu_0387	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Abu_0388	COG0442	prolyl-tRNA aminoacylation
Abu_0389	COG0668	transmembrane transport
Abu_0390	COG0617	tRNA 3'-terminal CCA addition
Abu_0393	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Abu_0394	COG1862	Preprotein translocase
Abu_0395	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Abu_0396	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Abu_0399	COG1360	Flagellar Motor Protein
Abu_0400	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Abu_0402	COG0495	leucyl-tRNA aminoacylation
Abu_0404	COG0285	dihydrofolate synthase activity
Abu_0410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Abu_0414	COG0745	RESPONSE REGULATOR receiver
Abu_0415	COG0642	Histidine kinase
Abu_0416	COG2081	HI0933 family
Abu_0417	COG0840	transmembrane signaling receptor activity
Abu_0420	COG5002	protein histidine kinase activity
Abu_0421	COG1692	metallophosphoesterase
Abu_0424	COG2226	methyltransferase
Abu_0425	COG1570	exodeoxyribonuclease VII activity
Abu_0426	COG0835	chemotaxis
Abu_0427	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Abu_0428	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Abu_0429	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Abu_0431	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Abu_0432	COG0459	protein refolding
Abu_0433	COG5002	protein histidine kinase activity
Abu_0434	COG0745	RESPONSE REGULATOR receiver
Abu_0435	COG1408	metallophosphoesterase
Abu_0440	COG1136	(ABC) transporter
Abu_0444	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Abu_0445	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Abu_0446	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Abu_0447	COG0352	thiamine-phosphate diphosphorylase activity
Abu_0448	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Abu_0450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Abu_0451	COG2264	protein methyltransferase activity
Abu_0452	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Abu_0453	COG3437	response regulator, receiver
Abu_0453	COG0784	Response regulator, receiver
Abu_0456	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Abu_0459	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Abu_0461	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Abu_0469	COG2274	protein secretion by the type I secretion system
Abu_0473	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Abu_0474	COG1090	epimerase
Abu_0475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Abu_0478	COG0481	GTPase activity
Abu_0479	COG1937	Protein conserved in bacteria
Abu_0482	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Abu_0484	COG0482	sulfurtransferase activity
Abu_0485	COG0482	sulfurtransferase activity
Abu_0486	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Abu_0487	COG0006	proline dipeptidase activity
Abu_0488	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Abu_0489	COG0402	S-adenosylhomocysteine deaminase activity
Abu_0490	COG0616	signal peptide processing
Abu_0493	COG0280	phosphate acetyltransferase
Abu_0494	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Abu_0496	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Abu_0497	COG2176	DNA-directed DNA polymerase activity
Abu_0503	COG2176	DNA-directed DNA polymerase activity
Abu_0505	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Abu_0508	COG5002	protein histidine kinase activity
Abu_0517	COG1058	Belongs to the CinA family
Abu_0517	COG1546	Belongs to the CinA family
Abu_0518	COG0579	oxidoreductase
Abu_0519	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Abu_0522	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Abu_0524	COG0667	Aldo Keto reductase
Abu_0525	COG0306	phosphate transporter
Abu_0528	COG0840	transmembrane signaling receptor activity
Abu_0529	COG0824	Thioesterase
Abu_0531	COG0501	Belongs to the peptidase M48B family
Abu_0532	COG1322	Protein conserved in bacteria
Abu_0536	COG0037	tRNA processing
Abu_0540	COG0052	Belongs to the universal ribosomal protein uS2 family
Abu_0541	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Abu_0542	COG1136	(ABC) transporter
Abu_0544	COG0194	GDP metabolic process
Abu_0545	COG5001	Diguanylate cyclase
Abu_0545	COG5002	protein histidine kinase activity
Abu_0546	COG2217	Heavy metal translocating P-type atpase
Abu_0549	COG4608	Belongs to the ABC transporter superfamily
Abu_0550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Abu_0551	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Abu_0553	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Abu_0554	COG1121	(ABC) transporter
Abu_0555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Abu_0556	COG2996	Protein conserved in bacteria
Abu_0557	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Abu_0561	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Abu_0563	COG0210	DNA helicase
Abu_0564	COG0569	domain protein
Abu_0564	COG0475	glutathione-regulated potassium exporter activity
Abu_0565	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Abu_0573	COG1331	Highly conserved protein containing a thioredoxin domain
Abu_0581	COG0525	valine-tRNA ligase activity
Abu_0583	COG4895	conserved protein (DUF2196)
Abu_0585	COG2814	Major facilitator Superfamily
Abu_0586	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Abu_0590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Abu_0591	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Abu_0592	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Abu_0594	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Abu_0605	COG0439	Biotin carboxylase
Abu_0606	COG2151	metal-sulfur cluster biosynthetic enzyme
Abu_0607	COG2166	iron-sulfur cluster assembly
Abu_0608	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Abu_0610	COG0396	ATPase activity
Abu_0611	COG0719	Fe-S assembly protein
Abu_0613	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Abu_0613	COG0822	iron-sulfur transferase activity
Abu_0613	COG2906	2 iron, 2 sulfur cluster binding
Abu_0614	COG2239	Acts as a magnesium transporter
Abu_0615	COG3706	GGDEF domain
Abu_0616	COG0165	Argininosuccinate lyase
Abu_0617	COG0835	chemotaxis
Abu_0617	COG0784	Response regulator, receiver
Abu_0618	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Abu_0619	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Abu_0621	COG0556	nucleotide-excision repair
Abu_0623	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Abu_0627	COG0840	transmembrane signaling receptor activity
Abu_0631	COG4191	Histidine kinase
Abu_0632	COG0840	transmembrane signaling receptor activity
Abu_0633	COG0840	transmembrane signaling receptor activity
Abu_0635	COG0698	ribose 5-phosphate isomerase
Abu_0636	COG0681	Belongs to the peptidase S26 family
Abu_0637	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Abu_0638	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Abu_0639	COG0193	aminoacyl-tRNA hydrolase activity
Abu_0642	COG0860	N-Acetylmuramoyl-L-alanine amidase
Abu_0644	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Abu_0647	COG0528	UMP kinase activity
Abu_0649	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Abu_0650	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Abu_0651	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Abu_0653	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Abu_0654	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Abu_0656	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Abu_0658	COG0305	Participates in initiation and elongation during chromosome replication
Abu_0659	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Abu_0661	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Abu_0665	COG0579	oxidoreductase
Abu_0666	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Abu_0667	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Abu_0668	COG0367	asparagine synthase
Abu_0675	COG1132	(ABC) transporter
Abu_0676	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Abu_0676	COG2755	lipolytic protein G-D-S-L family
Abu_0677	COG0438	transferase activity, transferring glycosyl groups
Abu_0678	COG0367	asparagine synthase
Abu_0680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Abu_0683	COG0482	sulfurtransferase activity
Abu_0684	COG0110	maltose O-acetyltransferase activity
Abu_0687	COG0438	transferase activity, transferring glycosyl groups
Abu_0688	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Abu_0688	COG0519	Catalyzes the synthesis of GMP from XMP
Abu_0693	COG0463	Glycosyl transferase, family 2
Abu_0694	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Abu_0695	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Abu_0696	COG1086	Polysaccharide biosynthesis protein
Abu_0698	COG1793	dna ligase
Abu_0699	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Abu_0700	COG0133	tryptophan synthase activity
Abu_0702	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Abu_0704	COG0848	biopolymer transport protein
Abu_0708	COG0577	efflux transmembrane transporter activity
Abu_0708	COG1136	(ABC) transporter
Abu_0709	COG1136	(ABC) transporter
Abu_0709	COG0577	efflux transmembrane transporter activity
Abu_0717	COG0735	belongs to the Fur family
Abu_0719	COG0114	fumarate hydratase activity
Abu_0721	COG3920	Histidine kinase
Abu_0722	COG0784	Response regulator, receiver
Abu_0723	COG4774	siderophore transport
Abu_0724	COG3128	pkhd-type hydroxylase
Abu_0726	COG4771	TonB-dependent receptor
Abu_0727	COG2819	hydrolase of the alpha beta superfamily
Abu_0728	COG0500	methyltransferase
Abu_0732	COG1966	Carbon starvation protein
Abu_0733	COG0012	GTP binding
Abu_0737	COG3123	guanosine phosphorylase activity
Abu_0740	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Abu_0741	COG0585	pseudouridine synthase activity
Abu_0743	COG0840	transmembrane signaling receptor activity
Abu_0744	COG0632	four-way junction helicase activity
Abu_0745	COG1181	Belongs to the D-alanine--D-alanine ligase family
Abu_0751	COG0051	transcription antitermination factor activity, RNA binding
Abu_0752	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Abu_0753	COG0088	Forms part of the polypeptide exit tunnel
Abu_0754	COG0089	rRNA binding
Abu_0755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Abu_0756	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Abu_0757	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Abu_0758	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Abu_0759	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Abu_0760	COG0255	Belongs to the universal ribosomal protein uL29 family
Abu_0761	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Abu_0762	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Abu_0763	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Abu_0764	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Abu_0765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Abu_0766	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Abu_0767	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Abu_0768	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Abu_0769	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Abu_0770	COG0200	Binds to the 23S rRNA
Abu_0771	COG0201	protein transport
Abu_0772	COG0024	Methionine aminopeptidase
Abu_0773	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Abu_0774	COG1573	uracil-dna glycosylase
Abu_0776	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Abu_0778	COG1032	radical SAM domain protein
Abu_0780	COG0563	adenylate kinase activity
Abu_0783	COG1064	alcohol dehydrogenase
Abu_0784	COG1979	alcohol dehydrogenase
Abu_0785	COG0840	transmembrane signaling receptor activity
Abu_0786	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Abu_0787	COG0322	excinuclease ABC activity
Abu_0788	COG0840	transmembrane signaling receptor activity
Abu_0790	COG0840	transmembrane signaling receptor activity
Abu_0791	COG0840	transmembrane signaling receptor activity
Abu_0792	COG0745	RESPONSE REGULATOR receiver
Abu_0794	COG0784	Response regulator, receiver
Abu_0794	COG2205	protein histidine kinase activity
Abu_0805	COG0829	nickel cation binding
Abu_0806	COG0832	Belongs to the urease beta subunit family
Abu_0806	COG0831	urea catabolic process
Abu_0807	COG0804	urea catabolic process
Abu_0808	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
Abu_0810	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Abu_0820	COG3706	GGDEF domain
Abu_0821	COG0708	Exodeoxyribonuclease III
Abu_0825	COG3040	lipid binding
Abu_0828	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Abu_0830	COG2200	EAL domain
Abu_0831	COG3279	Response regulator of the LytR AlgR family
Abu_0832	COG3275	phosphorelay sensor kinase activity
Abu_0833	COG1233	COG1233 Phytoene dehydrogenase and related
Abu_0834	COG0415	Belongs to the DNA photolyase family
Abu_0838	COG0166	Belongs to the GPI family
Abu_0847	COG0840	transmembrane signaling receptor activity
Abu_0848	COG1942	4-Oxalocrotonate Tautomerase
Abu_0849	COG0583	DNA-binding transcription factor activity
Abu_0850	COG0134	indole-3-glycerol-phosphate synthase activity
Abu_0852	COG0727	PFAM Uncharacterised protein family (UPF0153)
Abu_0853	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Abu_0855	COG0674	pyruvate-flavodoxin oxidoreductase activity
Abu_0855	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Abu_0856	COG1013	pyruvate-flavodoxin oxidoreductase activity
Abu_0858	COG2176	DNA-directed DNA polymerase activity
Abu_0859	COG0135	phosphoribosylanthranilate isomerase activity
Abu_0860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Abu_0864	COG1666	GTP binding
Abu_0866	COG2363	Small membrane protein
Abu_0867	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Abu_0870	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Abu_0871	COG0750	zinc metalloprotease
Abu_0872	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Abu_0873	COG1028	Short-chain dehydrogenase reductase Sdr
Abu_0874	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Abu_0876	COG0167	dihydroorotate dehydrogenase activity
Abu_0877	COG1132	(ABC) transporter
Abu_0878	COG0728	peptidoglycan biosynthetic process
Abu_0881	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Abu_0883	COG3340	Belongs to the peptidase S51 family
Abu_0884	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Abu_0885	COG3150	esterase
Abu_0886	COG1858	cytochrome C peroxidase
Abu_0889	COG0552	protein localization to endoplasmic reticulum
Abu_0890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Abu_0891	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Abu_0892	COG1418	mRNA catabolic process
Abu_0893	COG0742	ribosomal rna small subunit methyltransferase
Abu_0894	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Abu_0899	COG0300	oxidoreductase activity
Abu_0902	COG3258	Cytochrome c
Abu_0905	COG5002	protein histidine kinase activity
Abu_0906	COG0157	Belongs to the NadC ModD family
Abu_0908	COG1610	YqeY-like protein
Abu_0909	COG0488	(ABC) transporter
Abu_0911	COG0492	ferredoxin-NADP+ reductase activity
Abu_0912	COG0596	Alpha beta hydrolase
Abu_0921	COG0519	Catalyzes the synthesis of GMP from XMP
Abu_0921	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Abu_0922	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Abu_0925	COG0436	Aminotransferase
Abu_0926	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Abu_0933	COG2223	nitrite transmembrane transporter activity
Abu_0935	COG0310	cobalt ion transport
Abu_0939	COG2831	hemolysin activation secretion protein
Abu_0940	COG3210	domain, Protein
Abu_0940	COG3210	domain, Protein
Abu_0953	COG0628	permease
Abu_0958	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Abu_0960	COG0840	transmembrane signaling receptor activity
Abu_0961	COG0405	Gamma-glutamyltransferase
Abu_0963	COG1045	serine acetyltransferase
Abu_0964	COG1166	arginine decarboxylase activity
Abu_0965	COG0124	histidyl-tRNA synthetase
Abu_0966	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Abu_0967	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Abu_0968	COG0163	prenyltransferase activity
Abu_0970	COG0359	binds to the 23S rRNA
Abu_0971	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Abu_0972	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Abu_0974	COG0084	hydrolase, TatD family'
Abu_0976	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Abu_0977	COG0131	Imidazoleglycerol-phosphate dehydratase
Abu_0978	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Abu_0981	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Abu_0982	COG0456	acetyltransferase
Abu_0986	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Abu_0987	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Abu_0992	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Abu_0994	COG0784	Response regulator, receiver
Abu_0994	COG3437	response regulator, receiver
Abu_0996	COG0768	penicillin binding
Abu_1000	COG2884	Cell division ATP-binding protein ftsE
Abu_1001	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Abu_1003	COG0564	pseudouridine synthase activity
Abu_1004	COG0772	Belongs to the SEDS family
Abu_1006	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Abu_1007	COG3123	guanosine phosphorylase activity
Abu_1011	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Abu_1012	COG0066	3-isopropylmalate dehydratase activity
Abu_1013	COG0473	3-isopropylmalate dehydrogenase activity
Abu_1016	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Abu_1017	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Abu_1018	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Abu_1019	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Abu_1020	COG0202	RNA polymerase activity
Abu_1021	COG0203	ribosomal protein L17
Abu_1022	COG0154	amidase activity
Abu_1023	COG0517	IMP dehydrogenase activity
Abu_1023	COG0516	GMP reductase activity
Abu_1033	COG0484	heat shock protein binding
Abu_1036	COG3290	protein histidine kinase activity
Abu_1037	COG0784	Response regulator, receiver
Abu_1037	COG2205	protein histidine kinase activity
Abu_1039	COG1119	ATPase activity
Abu_1046	COG1733	regulation of RNA biosynthetic process
Abu_1047	COG2249	NAD(P)H dehydrogenase (quinone) activity
Abu_1049	COG2076	Multidrug Resistance protein
Abu_1052	COG1881	PFAM PEBP family protein
Abu_1053	COG0583	DNA-binding transcription factor activity
Abu_1054	COG2855	membrane
Abu_1057	COG1733	regulation of RNA biosynthetic process
Abu_1058	COG2249	NAD(P)H dehydrogenase (quinone) activity
Abu_1060	COG1902	pentaerythritol trinitrate reductase activity
Abu_1062	COG0778	Nitroreductase
Abu_1064	COG0488	(ABC) transporter
Abu_1065	COG1607	acyl-coa hydrolase
Abu_1067	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Abu_1068	COG0754	glutathionylspermidine amidase activity
Abu_1071	COG3177	Filamentation induced by cAMP protein fic
Abu_1072	COG3177	Filamentation induced by cAMP protein fic
Abu_1073	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Abu_1075	COG1496	oxidoreductase activity
Abu_1076	COG0281	malic enzyme
Abu_1076	COG0280	phosphate acetyltransferase
Abu_1077	COG0788	formyltetrahydrofolate deformylase activity
Abu_1078	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Abu_1083	COG0745	RESPONSE REGULATOR receiver
Abu_1085	COG0330	HflC and HflK could
Abu_1089	COG1271	oxidase subunit
Abu_1095	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Abu_1097	COG0546	phosphoglycolate phosphatase activity
Abu_1101	COG4771	TonB-dependent receptor
Abu_1103	COG1122	ATPase activity
Abu_1105	COG0406	alpha-ribazole phosphatase activity
Abu_1106	COG1132	(ABC) transporter
Abu_1108	COG0745	RESPONSE REGULATOR receiver
Abu_1109	COG0642	Histidine kinase
Abu_1116	COG0513	Belongs to the DEAD box helicase family
Abu_1118	COG0745	RESPONSE REGULATOR receiver
Abu_1125	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Abu_1127	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Abu_1128	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Abu_1130	COG0521	Mo-molybdopterin cofactor biosynthetic process
Abu_1131	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Abu_1140	COG0488	(ABC) transporter
Abu_1143	COG0243	molybdopterin cofactor binding
Abu_1146	COG1193	negative regulation of DNA recombination
Abu_1147	COG1253	flavin adenine dinucleotide binding
Abu_1150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Abu_1151	COG0004	ammonium transporteR
Abu_1154	COG0248	Ppx GppA phosphatase
Abu_1156	COG0028	Belongs to the TPP enzyme family
Abu_1157	COG0440	acetolactate synthase activity
Abu_1158	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Abu_1159	COG1674	ftsk spoiiie
Abu_1159	COG1196	nuclear chromosome segregation
Abu_1160	COG0745	RESPONSE REGULATOR receiver
Abu_1161	COG0642	Histidine kinase
Abu_1170	COG3012	SEC-C Motif Domain Protein
Abu_1171	COG0420	3'-5' exonuclease activity
Abu_1172	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
Abu_1175	COG1160	GTP binding
Abu_1176	COG0659	secondary active sulfate transmembrane transporter activity
Abu_1181	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Abu_1183	COG1185	polyribonucleotide nucleotidyltransferase activity
Abu_1185	COG2198	Histidine kinase
Abu_1185	COG0643	Histidine kinase
Abu_1186	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Abu_1187	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Abu_1188	COG2201	protein-glutamate methylesterase activity
Abu_1190	COG2223	nitrite transmembrane transporter activity
Abu_1191	COG0582	viral genome integration into host DNA
Abu_1195	COG0339	signal peptide processing
Abu_1196	COG2890	protein-(glutamine-N5) methyltransferase activity
Abu_1197	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Abu_1198	COG0494	nUDIX hydrolase
Abu_1199	COG0527	aspartate kinase activity
Abu_1202	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Abu_1204	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Abu_1207	COG3040	lipid binding
Abu_1209	COG4221	oxidoreductase activity
Abu_1210	COG0287	Prephenate dehydrogenase
Abu_1211	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Abu_1212	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Abu_1213	COG0612	Peptidase, M16
Abu_1214	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Abu_1219	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Abu_1221	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Abu_1221	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Abu_1227	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Abu_1232	COG0751	glycine-tRNA ligase activity
Abu_1236	COG0357	Ribosomal RNA small subunit methyltransferase G
Abu_1237	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Abu_1238	COG0113	porphobilinogen synthase activity
Abu_1239	COG4191	Histidine kinase
Abu_1239	COG0784	Response regulator, receiver
Abu_1240	COG0745	RESPONSE REGULATOR receiver
Abu_1243	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Abu_1243	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Abu_1244	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Abu_1245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Abu_1248	COG1663	tetraacyldisaccharide 4'-kinase activity
Abu_1250	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Abu_1255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Abu_1256	COG0805	protein transport
Abu_1257	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Abu_1258	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Abu_1266	COG2181	nitrate reductase activity
Abu_1266	COG0247	lactate metabolic process
Abu_1267	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Abu_1272	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Abu_1273	COG2199	diguanylate cyclase activity
Abu_1273	COG2200	EAL domain
Abu_1273	COG3287	FIST C domain
Abu_1274	COG1137	ATPase activity
Abu_1275	COG0802	atpase or kinase
Abu_1276	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Abu_1279	COG0137	argininosuccinate synthase activity
Abu_1280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Abu_1281	COG1696	Membrane protein involved in D-alanine export
Abu_1284	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Abu_1286	COG0659	secondary active sulfate transmembrane transporter activity
Abu_1288	COG0569	domain protein
Abu_1289	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Abu_1290	COG0745	RESPONSE REGULATOR receiver
Abu_1291	COG2205	protein histidine kinase activity
Abu_1293	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Abu_1294	COG0484	heat shock protein binding
Abu_1295	COG0133	tryptophan synthase activity
Abu_1299	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Abu_1301	COG2199	diguanylate cyclase activity
Abu_1302	COG0500	methyltransferase
Abu_1304	COG1333	cytochrome c biogenesis protein
Abu_1304	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Abu_1305	COG2195	Cleaves the N-terminal amino acid of tripeptides
Abu_1307	COG0840	transmembrane signaling receptor activity
Abu_1310	COG0653	protein targeting
Abu_1311	COG4591	ABC-type transport system involved in lipoprotein release permease component
Abu_1313	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Abu_1315	COG0039	L-malate dehydrogenase activity
Abu_1320	COG0275	rRNA processing
Abu_1322	COG0776	regulation of translation
Abu_1324	COG0582	viral genome integration into host DNA
Abu_1331	COG1204	response to ionizing radiation
Abu_1353	COG1959	2 iron, 2 sulfur cluster binding
Abu_1356	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Abu_1356	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Abu_1358	COG2201	protein-glutamate methylesterase activity
Abu_1361	COG0484	heat shock protein binding
Abu_1362	COG0789	Transcriptional regulator
Abu_1364	COG1131	(ABC) transporter
Abu_1365	COG0842	Transport permease protein
Abu_1366	COG0842	Transport permease protein
Abu_1367	COG0861	Integral membrane protein TerC family
Abu_1368	COG1114	Component of the transport system for branched-chain amino acids
Abu_1372	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Abu_1374	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Abu_1376	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Abu_1377	COG4773	Receptor
Abu_1379	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Abu_1384	COG1393	Belongs to the ArsC family
Abu_1390	COG0488	(ABC) transporter
Abu_1392	COG2171	N-acyltransferase activity
Abu_1393	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Abu_1395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Abu_1401	COG0309	Hydrogenase expression formation protein (HypE)
Abu_1403	COG2084	Dehydrogenase
Abu_1404	COG1401	restriction endodeoxyribonuclease activity
Abu_1406	COG0409	Hydrogenase expression formation protein
Abu_1407	COG0298	carbon dioxide binding
Abu_1408	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Abu_1410	COG0840	transmembrane signaling receptor activity
Abu_1412	COG2081	HI0933 family
Abu_1413	COG2354	Protein conserved in bacteria
Abu_1417	COG2814	Major facilitator Superfamily
Abu_1419	COG0301	tRNA thio-modification
Abu_1419	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Abu_1423	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Abu_1424	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Abu_1425	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Abu_1426	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
Abu_1427	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
Abu_1428	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Abu_1431	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Abu_1434	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
Abu_1435	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Abu_1439	COG1049	propionate catabolic process, 2-methylcitrate cycle
Abu_1441	COG2203	Gaf domain
Abu_1441	COG3706	GGDEF domain
Abu_1441	COG4251	negative regulation of phosphorylation
Abu_1441	COG5001	Diguanylate cyclase
Abu_1442	COG0217	transcriptional regulatory protein
Abu_1443	COG2853	Lipoprotein
Abu_1446	COG1611	Belongs to the LOG family
Abu_1447	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Abu_1450	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Abu_1457	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Abu_1460	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Abu_1467	COG3135	benzoate transporter
Abu_1468	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Abu_1469	COG2258	MOSC domain
Abu_1470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Abu_1471	COG0095	Lipoate-protein ligase
Abu_1472	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Abu_1473	COG0508	dehydrogenase complex catalyzes the overall conversion of
Abu_1474	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Abu_1475	COG1492	cobalamin metabolic process
Abu_1476	COG4773	Receptor
Abu_1479	COG0513	Belongs to the DEAD box helicase family
Abu_1484	COG1944	ATP diphosphatase activity
Abu_1487	COG0840	transmembrane signaling receptor activity
Abu_1488	COG0328	RNA-DNA hybrid ribonuclease activity
Abu_1489	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Abu_1495	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Abu_1497	COG0437	4 iron, 4 sulfur cluster binding
Abu_1508	COG1305	Transglutaminase-like
Abu_1510	COG0437	4 iron, 4 sulfur cluster binding
Abu_1511	COG3383	formate dehydrogenase (NAD+) activity
Abu_1511	COG0243	molybdopterin cofactor binding
Abu_1513	COG0709	Synthesizes selenophosphate from selenide and ATP
Abu_1524	COG1921	L-seryl-tRNASec selenium transferase activity
Abu_1539	COG1078	dGTPase activity
Abu_1540	COG5002	protein histidine kinase activity
Abu_1540	COG5001	Diguanylate cyclase
Abu_1541	COG0259	pyridoxamine-phosphate oxidase activity
Abu_1543	COG0513	Belongs to the DEAD box helicase family
Abu_1547	COG0326	Molecular chaperone. Has ATPase activity
Abu_1548	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Abu_1554	COG5002	protein histidine kinase activity
Abu_1554	COG5001	Diguanylate cyclase
Abu_1559	COG4335	DNA alkylation repair
Abu_1568	COG1595	DNA-templated transcription, initiation
Abu_1569	COG0010	Belongs to the arginase family
Abu_1570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Abu_1571	COG2207	Transcriptional regulator
Abu_1574	COG2207	Transcriptional regulator
Abu_1574	COG1609	Transcriptional regulator
Abu_1576	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Abu_1577	COG0668	transmembrane transport
Abu_1578	COG1227	inorganic diphosphatase activity
Abu_1581	COG1027	Aspartate ammonia-lyase
Abu_1582	COG0745	RESPONSE REGULATOR receiver
Abu_1584	COG1115	amino acid carrier protein
Abu_1585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Abu_1586	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Abu_1587	COG1047	Peptidyl-prolyl cis-trans
Abu_1590	COG0823	Involved in the tonB-independent uptake of proteins
Abu_1592	COG0848	biopolymer transport protein
Abu_1593	COG0811	peptide transport
Abu_1594	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Abu_1595	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Abu_1596	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Abu_1597	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Abu_1598	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Abu_1599	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Abu_1601	COG1475	DNA binding
Abu_1602	COG1192	Involved in chromosome partitioning
Abu_1606	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Abu_1607	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Abu_1608	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Abu_1609	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Abu_1610	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Abu_1611	COG0358	DNA primase activity
Abu_1613	COG0571	ribonuclease III activity
Abu_1614	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Abu_1616	COG0501	Belongs to the peptidase M48B family
Abu_1620	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Abu_1622	COG0706	membrane insertase activity
Abu_1623	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Abu_1625	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Abu_1626	COG0542	response to heat
Abu_1627	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Abu_1629	COG2326	polyphosphate kinase activity
Abu_1631	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Abu_1632	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Abu_1633	COG0179	Fumarylacetoacetate (FAA) hydrolase
Abu_1638	COG0138	bifunctional purine biosynthesis protein purh
Abu_1639	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Abu_1641	COG0739	heme binding
Abu_1642	COG0302	gtp cyclohydrolase
Abu_1643	COG0598	Magnesium transport protein CorA
Abu_1696	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Abu_1698	COG0606	chelatase, subunit chli
Abu_1700	COG0242	peptide deformylase activity
Abu_1701	COG0740	serine-type endopeptidase activity
Abu_1702	COG0544	peptidyl-prolyl cis-trans isomerase activity
Abu_1707	COG4974	Belongs to the 'phage' integrase family
Abu_1715	COG1196	nuclear chromosome segregation
Abu_1717	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Abu_1723	COG0626	cystathionine gamma-synthase activity
Abu_1726	COG0840	transmembrane signaling receptor activity
Abu_1728	COG3437	response regulator, receiver
Abu_1728	COG0784	Response regulator, receiver
Abu_1729	COG0840	transmembrane signaling receptor activity
Abu_1736	COG0745	RESPONSE REGULATOR receiver
Abu_1738	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
Abu_1741	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Abu_1742	COG1858	cytochrome C peroxidase
Abu_1748	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Abu_1749	COG0840	transmembrane signaling receptor activity
Abu_1751	COG0628	permease
Abu_1756	COG0351	phosphomethylpyrimidine kinase
Abu_1757	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Abu_1760	COG0348	domain, Protein
Abu_1762	COG4753	response regulator
Abu_1762	COG2207	Transcriptional regulator
Abu_1765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Abu_1769	COG0716	FMN binding
Abu_1772	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Abu_1773	COG0159	tryptophan synthase activity
Abu_1774	COG0038	chloride channel
Abu_1775	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Abu_1776	COG2255	four-way junction helicase activity
Abu_1777	COG0628	permease
Abu_1785	COG0731	radical SAM domain protein
Abu_1786	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Abu_1788	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Abu_1791	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Abu_1793	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Abu_1795	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Abu_1797	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Abu_1797	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Abu_1798	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Abu_1799	COG1368	sulfuric ester hydrolase activity
Abu_1800	COG0859	PFAM glycosyl transferase family 9
Abu_1802	COG0859	PFAM glycosyl transferase family 9
Abu_1804	COG2194	sulfuric ester hydrolase activity
Abu_1807	COG1696	Membrane protein involved in D-alanine export
Abu_1808	COG0297	glycogen (starch) synthase activity
Abu_1809	COG0463	Glycosyl transferase, family 2
Abu_1810	COG0438	transferase activity, transferring glycosyl groups
Abu_1817	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Abu_1819	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Abu_1822	COG0859	PFAM glycosyl transferase family 9
Abu_1824	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Abu_1826	COG0493	'glutamate synthase
Abu_1827	COG0067	glutamate synthase
Abu_1827	COG0069	glutamate synthase activity
Abu_1827	COG0070	glutamate synthase
Abu_1830	COG0840	transmembrane signaling receptor activity
Abu_1831	COG0840	transmembrane signaling receptor activity
Abu_1834	COG1739	Uncharacterized protein family UPF0029
Abu_1836	COG0196	riboflavin kinase activity
Abu_1837	COG2226	methyltransferase
Abu_1838	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Abu_1840	COG0277	FAD linked oxidase domain protein
Abu_1841	COG1295	ribonuclease BN
Abu_1843	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Abu_1845	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Abu_1846	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Abu_1847	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Abu_1848	COG0284	orotidine-5'-phosphate decarboxylase activity
Abu_1853	COG1918	ferrous iron import across plasma membrane
Abu_1854	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Abu_1854	COG1918	ferrous iron import across plasma membrane
Abu_1859	COG2217	Heavy metal translocating P-type atpase
Abu_1861	COG4773	Receptor
Abu_1863	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Abu_1866	COG1278	Cold shock
Abu_1868	COG2207	Transcriptional regulator
Abu_1868	COG4753	response regulator
Abu_1869	COG3852	Histidine kinase
Abu_1879	COG0450	alkyl hydroperoxide reductase
Abu_1880	COG3118	belongs to the thioredoxin family
Abu_1883	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Abu_1884	COG0085	RNA polymerase activity
Abu_1885	COG0222	ribosome binding
Abu_1886	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Abu_1887	COG0081	regulation of translation
Abu_1888	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Abu_1889	COG0250	Participates in transcription elongation, termination and antitermination
Abu_1892	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Abu_1893	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Abu_1899	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Abu_1900	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Abu_1901	COG0444	Belongs to the ABC transporter superfamily
Abu_1902	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Abu_1903	COG0174	glutamine synthetase
Abu_1905	COG0314	molybdopterin synthase activity
Abu_1907	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Abu_1908	COG1968	undecaprenyl-diphosphatase activity
Abu_1909	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Abu_1910	COG0772	Belongs to the SEDS family
Abu_1912	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Abu_1920	COG0542	response to heat
Abu_1921	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Abu_1922	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Abu_1926	COG2030	dehydratase
Abu_1930	COG0840	transmembrane signaling receptor activity
Abu_1931	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Abu_1936	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Abu_1938	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Abu_1939	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Abu_1940	COG1157	protein secretion by the type III secretion system
Abu_1942	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Abu_1946	COG1677	Flagellar hook-basal body complex protein FliE
Abu_1948	COG0455	bacterial-type flagellum organization
Abu_1949	COG1419	protein localization to endoplasmic reticulum
Abu_1952	COG3951	Flagellar rod assembly protein muramidase FlgJ
Abu_1957	COG1749	Flagellar hook protein flgE
Abu_1958	COG4786	Flagellar basal body rod
Abu_1960	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Abu_1962	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Abu_1963	COG1766	The M ring may be actively involved in energy transduction
Abu_1964	COG1815	bacterial-type flagellum-dependent cell motility
Abu_1965	COG4786	Flagellar basal body rod
Abu_1967	COG0745	RESPONSE REGULATOR receiver
Abu_1971	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Abu_1973	COG0228	four-way junction DNA binding
Abu_1974	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Abu_1975	COG0564	pseudouridine synthase activity
Abu_1976	COG1519	Transferase
Abu_1978	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Abu_1979	COG0752	glycyl-tRNA synthetase alpha subunit
Abu_1981	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Abu_1983	COG0826	peptidase U32
Abu_1984	COG0840	transmembrane signaling receptor activity
Abu_1985	COG0497	DNA recombination
Abu_1986	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Abu_1987	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Abu_1988	COG0049	tRNA binding
Abu_1989	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Abu_1991	COG2814	Major facilitator Superfamily
Abu_1992	COG4771	TonB-dependent receptor
Abu_1995	COG1116	anion transmembrane transporter activity
Abu_1996	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Abu_2004	COG0512	Glutamine amidotransferase of anthranilate synthase
Abu_2005	COG1840	ABC-type Fe3 transport system, periplasmic component
Abu_2006	COG1178	ABC-type Fe3 transport system permease component
Abu_2009	COG4774	siderophore transport
Abu_2017	COG2183	response to ionizing radiation
Abu_2019	COG0251	oxidation-reduction process
Abu_2022	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Abu_2024	COG0586	Pfam SNARE associated Golgi protein
Abu_2025	COG0335	large ribosomal subunit rRNA binding
Abu_2026	COG0336	Belongs to the RNA methyltransferase TrmD family
Abu_2028	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Abu_2029	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Abu_2030	COG0356	it plays a direct role in the translocation of protons across the membrane
Abu_2032	COG4773	Receptor
Abu_2034	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Abu_2036	COG0157	Belongs to the NadC ModD family
Abu_2039	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Abu_2041	COG0083	homoserine kinase activity
Abu_2043	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Abu_2044	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Abu_2045	COG0779	Required for maturation of 30S ribosomal subunits
Abu_2046	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Abu_2046	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Abu_2047	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Abu_2048	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Abu_2049	COG1185	polyribonucleotide nucleotidyltransferase activity
Abu_2049	COG0539	negative regulation of cytoplasmic translation
Abu_2050	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Abu_2051	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Abu_2052	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Abu_2052	COG0072	phenylalanine-tRNA ligase activity
Abu_2053	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Abu_2054	COG0537	adenosine 5'-monophosphoramidase activity
Abu_2055	COG0825	malonyl-CoA metabolic process
Abu_2056	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Abu_2057	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Abu_2059	COG0602	queuosine metabolic process
Abu_2061	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Abu_2063	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Abu_2065	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Abu_2067	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Abu_2068	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Abu_2069	COG1074	ATP-dependent DNA helicase activity
Abu_2071	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Abu_2081	COG3278	Belongs to the heme-copper respiratory oxidase family
Abu_2082	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Abu_2083	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Abu_2084	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Abu_2087	COG1242	4 iron, 4 sulfur cluster binding
Abu_2088	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Abu_2089	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Abu_2090	COG0492	ferredoxin-NADP+ reductase activity
Abu_2091	COG3118	belongs to the thioredoxin family
Abu_2092	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Abu_2097	COG0642	Histidine kinase
Abu_2098	COG0745	RESPONSE REGULATOR receiver
Abu_2100	COG0129	dihydroxy-acid dehydratase activity
Abu_2114	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Abu_2117	COG0585	pseudouridine synthase activity
Abu_2120	COG0793	Belongs to the peptidase S41A family
Abu_2121	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Abu_2122	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Abu_2123	COG0047	phosphoribosylformylglycinamidine synthase activity
Abu_2125	COG0204	Acyl-transferase
Abu_2126	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Abu_2127	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Abu_2128	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Abu_2129	COG0018	arginyl-trna synthetase
Abu_2131	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Abu_2133	COG0126	phosphoglycerate kinase activity
Abu_2134	COG0149	triose-phosphate isomerase activity
Abu_2135	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Abu_2136	COG0019	diaminopimelate decarboxylase activity
Abu_2137	COG1605	Chorismate mutase
Abu_2137	COG0077	Prephenate dehydratase
Abu_2138	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Abu_2139	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Abu_2141	COG0424	maF-like protein
Abu_2144	COG0791	NLP P60 protein
Abu_2147	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Abu_2148	COG1012	belongs to the aldehyde dehydrogenase family
Abu_2150	COG1704	LemA family
Abu_2153	COG0546	phosphoglycolate phosphatase activity
Abu_2154	COG0783	Belongs to the Dps family
Abu_2157	COG2814	Major facilitator Superfamily
Abu_2160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Abu_2161	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Abu_2165	COG1595	DNA-templated transcription, initiation
Abu_2167	COG2081	HI0933 family
Abu_2170	COG1959	2 iron, 2 sulfur cluster binding
Abu_2173	COG0175	sulfate reduction
Abu_2174	COG0175	sulfate reduction
Abu_2175	COG2895	sulfate adenylyltransferase (ATP) activity
Abu_2178	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Abu_2184	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Abu_2187	COG4232	protein-disulfide reductase activity
Abu_2188	COG0189	ligase activity
Abu_2191	COG2199	diguanylate cyclase activity
Abu_2191	COG3287	FIST C domain
Abu_2191	COG2200	EAL domain
Abu_2192	COG0688	phosphatidylethanolamine metabolic process
Abu_2194	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Abu_2195	COG0443	Heat shock 70 kDa protein
Abu_2196	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Abu_2199	COG0101	tRNA pseudouridine synthase activity
Abu_2202	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Abu_2203	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Abu_2204	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Abu_2207	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Abu_2210	COG0445	tRNA wobble uridine modification
Abu_2214	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Abu_2215	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Abu_2216	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Abu_2217	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Abu_2218	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Abu_2220	COG1252	NADH dehydrogenase
Abu_2221	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Abu_2223	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Abu_2226	COG2814	Major facilitator Superfamily
Abu_2227	COG0659	secondary active sulfate transmembrane transporter activity
Abu_2231	COG1222	aaa ATPase
Abu_2233	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Abu_2234	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Abu_2237	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Abu_2240	COG0148	phosphopyruvate hydratase activity
Abu_2241	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Abu_2243	COG1086	Polysaccharide biosynthesis protein
Abu_2244	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Abu_2245	COG1083	cytidylyl-transferase
Abu_2246	COG2089	acid synthase
Abu_2250	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Abu_2254	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Abu_2256	COG0348	domain, Protein
Abu_2257	COG0504	CTP synthase activity
Abu_2258	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Abu_2262	COG0587	DNA-directed DNA polymerase activity
Abu_2263	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Abu_2266	COG0315	cyclic pyranopterin monophosphate synthase activity
Abu_2267	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Abu_2273	COG0670	Belongs to the BI1 family
Abu_2274	COG0352	thiamine-phosphate diphosphorylase activity
Abu_2276	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Abu_2277	COG0233	cytoplasmic translational termination
Abu_2278	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Abu_2282	COG3022	response to hydroperoxide
Abu_2285	COG1408	metallophosphoesterase
Abu_2287	COG4774	siderophore transport
Abu_2288	COG2207	Transcriptional regulator
Abu_2288	COG1609	Transcriptional regulator
Abu_2289	COG0071	Belongs to the small heat shock protein (HSP20) family
Abu_2290	COG2703	oxygen carrier activity
Abu_2291	COG0840	transmembrane signaling receptor activity
Abu_2295	COG1305	Transglutaminase-like
Abu_2297	COG4208	sulfate ABC transporter
Abu_2298	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Abu_2300	COG2199	diguanylate cyclase activity
Abu_2300	COG2200	EAL domain
Abu_2300	COG3287	FIST C domain
Abu_2307	COG2308	Evidence 4 Homologs of previously reported genes of
Abu_2308	COG1217	gtp-binding protein TYPA
Abu_2309	COG2391	methyltransferase activity
Abu_2310	COG0425	Belongs to the sulfur carrier protein TusA family
Abu_2317	COG3706	GGDEF domain
Abu_2325	COG0745	RESPONSE REGULATOR receiver
Abu_2326	COG2770	Histidine kinase
Abu_2326	COG2205	protein histidine kinase activity
Abu_2327	COG2226	methyltransferase
Abu_2329	COG0784	Response regulator, receiver
Abu_2329	COG3437	response regulator, receiver
Abu_2330	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Abu_2331	COG2066	Belongs to the glutaminase family
Abu_2335	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group