locus-tag	class	description
ACBT_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACBT_0002	COG0592	DNA-directed DNA polymerase activity
ACBT_0003	COG0187	DNA topoisomerase II activity
ACBT_0004	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACBT_0008	COG0500	methyltransferase
ACBT_0009	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACBT_0013	COG3174	membrane
ACBT_0017	COG2895	sulfate adenylyltransferase (ATP) activity
ACBT_0018	COG0175	sulfate reduction
ACBT_0019	COG0175	sulfate reduction
ACBT_0022	COG1959	2 iron, 2 sulfur cluster binding
ACBT_0025	COG2081	HI0933 family
ACBT_0026	COG0840	transmembrane signaling receptor activity
ACBT_0028	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACBT_0029	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACBT_0030	COG3706	GGDEF domain
ACBT_0032	COG2814	Major facilitator Superfamily
ACBT_0033	COG0783	Belongs to the Dps family
ACBT_0034	COG0546	phosphoglycolate phosphatase activity
ACBT_0036	COG1012	belongs to the aldehyde dehydrogenase family
ACBT_0037	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACBT_0042	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACBT_0043	COG3022	response to hydroperoxide
ACBT_0047	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACBT_0048	COG0233	cytoplasmic translational termination
ACBT_0050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACBT_0052	COG0352	thiamine-phosphate diphosphorylase activity
ACBT_0053	COG0670	Belongs to the BI1 family
ACBT_0088	COG0840	transmembrane signaling receptor activity
ACBT_0089	COG0840	transmembrane signaling receptor activity
ACBT_0091	COG1278	Cold shock
ACBT_0093	COG2337	Toxic component of a toxin-antitoxin (TA) module
ACBT_0095	COG4191	Histidine kinase
ACBT_0097	COG4895	conserved protein (DUF2196)
ACBT_0098	COG0582	viral genome integration into host DNA
ACBT_0104	COG4771	TonB-dependent receptor
ACBT_0105	COG0428	transporter
ACBT_0106	COG0840	transmembrane signaling receptor activity
ACBT_0109	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACBT_0110	COG4191	Histidine kinase
ACBT_0111	COG2197	response regulator
ACBT_0114	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACBT_0119	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACBT_0122	COG1196	nuclear chromosome segregation
ACBT_0122	COG1674	ftsk spoiiie
ACBT_0124	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACBT_0125	COG0784	Response regulator, receiver
ACBT_0125	COG4191	Histidine kinase
ACBT_0135	COG0849	cell division
ACBT_0138	COG4286	Uncharacterised protein family (UPF0160)
ACBT_0153	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACBT_0160	COG2356	endonuclease I
ACBT_0163	COG1475	DNA binding
ACBT_0164	COG1192	Involved in chromosome partitioning
ACBT_0170	COG1201	RNA secondary structure unwinding
ACBT_0187	COG2105	PFAM AIG2 family protein
ACBT_0190	COG0776	regulation of translation
ACBT_0201	COG4286	Uncharacterised protein family (UPF0160)
ACBT_0205	COG4895	conserved protein (DUF2196)
ACBT_0206	COG0582	viral genome integration into host DNA
ACBT_0208	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACBT_0210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACBT_0211	COG4191	Histidine kinase
ACBT_0212	COG2197	response regulator
ACBT_0215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACBT_0219	COG1742	UPF0060 membrane protein
ACBT_0222	COG0840	transmembrane signaling receptor activity
ACBT_0223	COG0840	transmembrane signaling receptor activity
ACBT_0226	COG1045	serine acetyltransferase
ACBT_0227	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACBT_0228	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACBT_0232	COG1116	anion transmembrane transporter activity
ACBT_0239	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACBT_0240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACBT_0242	COG1116	anion transmembrane transporter activity
ACBT_0243	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACBT_0244	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACBT_0245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACBT_0248	COG0840	transmembrane signaling receptor activity
ACBT_0251	COG0077	Prephenate dehydratase
ACBT_0251	COG1605	Chorismate mutase
ACBT_0260	COG4569	acetaldehyde dehydrogenase (acetylating) activity
ACBT_0267	COG0492	ferredoxin-NADP+ reductase activity
ACBT_0274	COG0730	response to heat
ACBT_0282	COG2204	response regulator
ACBT_0283	COG1028	Short-chain dehydrogenase reductase Sdr
ACBT_0284	COG0473	3-isopropylmalate dehydrogenase activity
ACBT_0287	COG3706	GGDEF domain
ACBT_0291	COG0745	RESPONSE REGULATOR receiver
ACBT_0294	COG0071	Belongs to the small heat shock protein (HSP20) family
ACBT_0304	COG0514	ATP-dependent DNA helicase (RecQ)
ACBT_0305	COG1192	Involved in chromosome partitioning
ACBT_0306	COG1475	DNA binding
ACBT_0308	COG0305	Participates in initiation and elongation during chromosome replication
ACBT_0322	COG1028	Short-chain dehydrogenase reductase Sdr
ACBT_0323	COG1083	cytidylyl-transferase
ACBT_0325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACBT_0326	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACBT_0328	COG1011	Hydrolase
ACBT_0330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACBT_0331	COG1088	dTDP-glucose 4,6-dehydratase activity
ACBT_0333	COG4804	nuclease activity
ACBT_0334	COG2089	acid synthase
ACBT_0336	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACBT_0339	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACBT_0340	COG0148	phosphopyruvate hydratase activity
ACBT_0343	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACBT_0346	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACBT_0347	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ACBT_0348	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ACBT_0349	COG0315	cyclic pyranopterin monophosphate synthase activity
ACBT_0352	COG1007	ATP synthesis coupled electron transport
ACBT_0354	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACBT_0355	COG0713	ATP synthesis coupled electron transport
ACBT_0356	COG0839	Belongs to the complex I subunit 6 family
ACBT_0357	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACBT_0358	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACBT_0362	COG0649	NAD binding
ACBT_0363	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACBT_0364	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACBT_0365	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACBT_0366	COG1222	aaa ATPase
ACBT_0369	COG0659	secondary active sulfate transmembrane transporter activity
ACBT_0370	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ACBT_0371	COG1252	NADH dehydrogenase
ACBT_0373	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACBT_0374	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACBT_0375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACBT_0376	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACBT_0377	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACBT_0381	COG0445	tRNA wobble uridine modification
ACBT_0382	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACBT_0383	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACBT_0385	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACBT_0386	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACBT_0387	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACBT_0390	COG0101	tRNA pseudouridine synthase activity
ACBT_0392	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACBT_0393	COG0443	Heat shock 70 kDa protein
ACBT_0395	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ACBT_0397	COG0688	phosphatidylethanolamine metabolic process
ACBT_0398	COG2199	diguanylate cyclase activity
ACBT_0398	COG3287	FIST C domain
ACBT_0398	COG2200	EAL domain
ACBT_0401	COG0189	ligase activity
ACBT_0402	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACBT_0403	COG3118	belongs to the thioredoxin family
ACBT_0410	COG1028	Short-chain dehydrogenase reductase Sdr
ACBT_0412	COG0642	Histidine kinase
ACBT_0413	COG0745	RESPONSE REGULATOR receiver
ACBT_0415	COG0129	dihydroxy-acid dehydratase activity
ACBT_0421	COG1136	(ABC) transporter
ACBT_0423	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACBT_0424	COG0585	pseudouridine synthase activity
ACBT_0427	COG0793	Belongs to the peptidase S41A family
ACBT_0429	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACBT_0430	COG0047	phosphoribosylformylglycinamidine synthase activity
ACBT_0432	COG0204	Acyl-transferase
ACBT_0434	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACBT_0435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACBT_0436	COG0018	arginyl-trna synthetase
ACBT_0438	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACBT_0439	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACBT_0440	COG0126	phosphoglycerate kinase activity
ACBT_0441	COG0149	triose-phosphate isomerase activity
ACBT_0442	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ACBT_0443	COG0019	diaminopimelate decarboxylase activity
ACBT_0444	COG1605	Chorismate mutase
ACBT_0444	COG0077	Prephenate dehydratase
ACBT_0445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACBT_0446	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACBT_0448	COG0424	maF-like protein
ACBT_0450	COG0791	NLP P60 protein
ACBT_0451	COG0791	NLP P60 protein
ACBT_0455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACBT_0456	COG3118	belongs to the thioredoxin family
ACBT_0457	COG0492	ferredoxin-NADP+ reductase activity
ACBT_0458	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACBT_0459	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACBT_0463	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACBT_0464	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACBT_0465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACBT_0466	COG3278	Belongs to the heme-copper respiratory oxidase family
ACBT_0476	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACBT_0477	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACBT_0478	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACBT_0479	COG1185	polyribonucleotide nucleotidyltransferase activity
ACBT_0479	COG0539	negative regulation of cytoplasmic translation
ACBT_0480	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACBT_0481	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACBT_0482	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACBT_0482	COG0072	phenylalanine-tRNA ligase activity
ACBT_0483	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACBT_0484	COG0537	adenosine 5'-monophosphoramidase activity
ACBT_0485	COG0825	malonyl-CoA metabolic process
ACBT_0486	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACBT_0487	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACBT_0489	COG0602	queuosine metabolic process
ACBT_0491	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACBT_0496	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ACBT_0498	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACBT_0499	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACBT_0502	COG0356	it plays a direct role in the translocation of protons across the membrane
ACBT_0503	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACBT_0504	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACBT_0506	COG0336	Belongs to the RNA methyltransferase TrmD family
ACBT_0507	COG0335	large ribosomal subunit rRNA binding
ACBT_0508	COG0586	Pfam SNARE associated Golgi protein
ACBT_0509	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACBT_0512	COG0251	oxidation-reduction process
ACBT_0514	COG2183	response to ionizing radiation
ACBT_0520	COG1178	ABC-type Fe3 transport system permease component
ACBT_0521	COG1840	ABC-type Fe3 transport system, periplasmic component
ACBT_0522	COG0512	Glutamine amidotransferase of anthranilate synthase
ACBT_0530	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACBT_0531	COG0768	penicillin binding
ACBT_0532	COG0772	Belongs to the SEDS family
ACBT_0533	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACBT_0534	COG1968	undecaprenyl-diphosphatase activity
ACBT_0535	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ACBT_0537	COG0314	molybdopterin synthase activity
ACBT_0539	COG0174	glutamine synthetase
ACBT_0540	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACBT_0541	COG0444	Belongs to the ABC transporter superfamily
ACBT_0542	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACBT_0543	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACBT_0544	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACBT_0549	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACBT_0550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACBT_0553	COG0250	Participates in transcription elongation, termination and antitermination
ACBT_0554	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACBT_0555	COG0081	regulation of translation
ACBT_0556	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACBT_0557	COG0222	ribosome binding
ACBT_0558	COG0085	RNA polymerase activity
ACBT_0559	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACBT_0562	COG0582	viral genome integration into host DNA
ACBT_0584	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ACBT_0585	COG0732	type I restriction modification DNA specificity domain
ACBT_0589	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ACBT_0590	COG0840	transmembrane signaling receptor activity
ACBT_0591	COG0450	alkyl hydroperoxide reductase
ACBT_0592	COG3118	belongs to the thioredoxin family
ACBT_0593	COG1971	Probably functions as a manganese efflux pump
ACBT_0597	COG0840	transmembrane signaling receptor activity
ACBT_0598	COG2814	Major facilitator Superfamily
ACBT_0600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACBT_0601	COG0049	tRNA binding
ACBT_0602	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACBT_0603	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACBT_0604	COG0497	DNA recombination
ACBT_0605	COG0840	transmembrane signaling receptor activity
ACBT_0605	COG0840	transmembrane signaling receptor activity
ACBT_0606	COG0826	peptidase U32
ACBT_0608	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACBT_0610	COG0752	glycyl-tRNA synthetase alpha subunit
ACBT_0611	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACBT_0613	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACBT_0613	COG1519	Transferase
ACBT_0614	COG0564	pseudouridine synthase activity
ACBT_0615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACBT_0616	COG0228	four-way junction DNA binding
ACBT_0617	COG1837	Belongs to the UPF0109 family
ACBT_0618	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACBT_0622	COG0745	RESPONSE REGULATOR receiver
ACBT_0624	COG4786	Flagellar basal body rod
ACBT_0625	COG1815	bacterial-type flagellum-dependent cell motility
ACBT_0626	COG1766	The M ring may be actively involved in energy transduction
ACBT_0627	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACBT_0629	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACBT_0631	COG1749	Flagellar hook protein flgE
ACBT_0632	COG1749	Flagellar hook protein flgE
ACBT_0636	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACBT_0640	COG1419	protein localization to endoplasmic reticulum
ACBT_0641	COG0455	bacterial-type flagellum organization
ACBT_0643	COG1677	Flagellar hook-basal body complex protein FliE
ACBT_0647	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACBT_0649	COG1157	protein secretion by the type III secretion system
ACBT_0650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACBT_0651	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACBT_0652	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACBT_0654	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACBT_0655	COG1970	mechanosensitive ion channel activity
ACBT_0661	COG2030	dehydratase
ACBT_0664	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACBT_0665	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACBT_0666	COG0542	response to heat
ACBT_0673	COG1295	ribonuclease BN
ACBT_0674	COG0277	FAD linked oxidase domain protein
ACBT_0676	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACBT_0677	COG2226	methyltransferase
ACBT_0680	COG1739	Uncharacterized protein family UPF0029
ACBT_0684	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACBT_0686	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ACBT_0687	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACBT_0688	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACBT_0689	COG0284	orotidine-5'-phosphate decarboxylase activity
ACBT_0702	COG0483	inositol monophosphate 1-phosphatase activity
ACBT_0703	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACBT_0705	COG0859	PFAM glycosyl transferase family 9
ACBT_0708	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACBT_0709	COG1368	sulfuric ester hydrolase activity
ACBT_0710	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACBT_0712	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACBT_0721	COG0438	transferase activity, transferring glycosyl groups
ACBT_0723	COG0297	glycogen (starch) synthase activity
ACBT_0724	COG2194	sulfuric ester hydrolase activity
ACBT_0730	COG1368	sulfuric ester hydrolase activity
ACBT_0731	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ACBT_0732	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACBT_0732	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACBT_0736	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACBT_0738	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACBT_0741	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACBT_0743	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ACBT_0751	COG4628	conserved protein (DUF2132)
ACBT_0756	COG1570	exodeoxyribonuclease VII activity
ACBT_0757	COG0835	chemotaxis
ACBT_0758	COG0745	RESPONSE REGULATOR receiver
ACBT_0760	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACBT_0761	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACBT_0763	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACBT_0764	COG0459	protein refolding
ACBT_0768	COG5002	protein histidine kinase activity
ACBT_0770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACBT_0771	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACBT_0772	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ACBT_0773	COG0352	thiamine-phosphate diphosphorylase activity
ACBT_0774	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACBT_0776	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACBT_0777	COG2264	protein methyltransferase activity
ACBT_0778	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACBT_0779	COG0628	permease
ACBT_0780	COG2255	four-way junction helicase activity
ACBT_0781	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ACBT_0782	COG0159	tryptophan synthase activity
ACBT_0783	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ACBT_0785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ACBT_0790	COG4753	response regulator
ACBT_0790	COG2207	Transcriptional regulator
ACBT_0791	COG4191	Histidine kinase
ACBT_0792	COG0348	domain, Protein
ACBT_0794	COG3706	GGDEF domain
ACBT_0796	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACBT_0798	COG1846	Transcriptional regulator
ACBT_0799	COG1028	Short-chain dehydrogenase reductase Sdr
ACBT_0805	COG2326	polyphosphate kinase activity
ACBT_0806	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACBT_0807	COG0740	serine-type endopeptidase activity
ACBT_0808	COG0242	peptide deformylase activity
ACBT_0811	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACBT_0814	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ACBT_0815	COG2095	MarC family integral membrane protein
ACBT_0817	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACBT_0818	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACBT_0820	COG0481	GTPase activity
ACBT_0821	COG2885	chlorophyll binding
ACBT_0821	COG3047	cAMP biosynthetic process
ACBT_0823	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACBT_0825	COG0482	sulfurtransferase activity
ACBT_0826	COG0482	sulfurtransferase activity
ACBT_0827	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACBT_0828	COG0006	proline dipeptidase activity
ACBT_0829	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACBT_0830	COG0402	S-adenosylhomocysteine deaminase activity
ACBT_0831	COG0616	signal peptide processing
ACBT_0833	COG0280	phosphate acetyltransferase
ACBT_0834	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACBT_0835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACBT_0836	COG2176	DNA-directed DNA polymerase activity
ACBT_0842	COG2176	DNA-directed DNA polymerase activity
ACBT_0844	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACBT_0846	COG0745	RESPONSE REGULATOR receiver
ACBT_0856	COG1058	Belongs to the CinA family
ACBT_0856	COG1546	Belongs to the CinA family
ACBT_0857	COG0579	oxidoreductase
ACBT_0858	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACBT_0862	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACBT_0863	COG0052	Belongs to the universal ribosomal protein uS2 family
ACBT_0864	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACBT_0865	COG1136	(ABC) transporter
ACBT_0867	COG0194	GDP metabolic process
ACBT_0869	COG2217	Heavy metal translocating P-type atpase
ACBT_0872	COG0582	viral genome integration into host DNA
ACBT_0880	COG4608	Belongs to the ABC transporter superfamily
ACBT_0881	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACBT_0882	COG1227	inorganic diphosphatase activity
ACBT_0883	COG0668	transmembrane transport
ACBT_0884	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACBT_0886	COG0010	Belongs to the arginase family
ACBT_0888	COG1278	Cold shock
ACBT_0889	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACBT_0891	COG0573	inorganic phosphate transmembrane transporter activity
ACBT_0893	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACBT_0899	COG2995	paraquat-inducible protein a
ACBT_0900	COG3008	intermembrane lipid transfer
ACBT_0902	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ACBT_0903	COG0326	Molecular chaperone. Has ATPase activity
ACBT_0904	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACBT_0905	COG1129	ABC transporter
ACBT_0905	COG0842	Transport permease protein
ACBT_0906	COG0842	Transport permease protein
ACBT_0908	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACBT_0909	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ACBT_0910	COG0840	transmembrane signaling receptor activity
ACBT_0912	COG2199	diguanylate cyclase activity
ACBT_0912	COG2200	EAL domain
ACBT_0912	COG3287	FIST C domain
ACBT_0915	COG0513	Belongs to the DEAD box helicase family
ACBT_0917	COG0259	pyridoxamine-phosphate oxidase activity
ACBT_0922	COG5002	protein histidine kinase activity
ACBT_0923	COG1121	(ABC) transporter
ACBT_0924	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACBT_0925	COG2996	Protein conserved in bacteria
ACBT_0926	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ACBT_0928	COG0673	inositol 2-dehydrogenase activity
ACBT_0931	COG0210	DNA helicase
ACBT_0932	COG0569	domain protein
ACBT_0932	COG0475	glutathione-regulated potassium exporter activity
ACBT_0933	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACBT_0954	COG1921	L-seryl-tRNASec selenium transferase activity
ACBT_0958	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACBT_0959	COG0671	phosphoesterase, PA-phosphatase related
ACBT_0962	COG1408	metallophosphoesterase
ACBT_0967	COG1136	(ABC) transporter
ACBT_0969	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACBT_0971	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACBT_0973	COG0386	Belongs to the glutathione peroxidase family
ACBT_0975	COG1078	dGTPase activity
ACBT_0981	COG1305	Transglutaminase-like
ACBT_0984	COG4565	transcriptional regulatory protein
ACBT_0991	COG0437	4 iron, 4 sulfur cluster binding
ACBT_0993	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACBT_0997	COG2998	abc-type tungstate transport system, permease component
ACBT_0998	COG4662	Binding-protein-dependent transport system inner membrane component
ACBT_1002	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACBT_1004	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACBT_1005	COG0306	phosphate transporter
ACBT_1008	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACBT_1009	COG0328	RNA-DNA hybrid ribonuclease activity
ACBT_1010	COG0840	transmembrane signaling receptor activity
ACBT_1013	COG0513	Belongs to the DEAD box helicase family
ACBT_1014	COG2217	Heavy metal translocating P-type atpase
ACBT_1016	COG1032	radical SAM domain protein
ACBT_1017	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACBT_1018	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACBT_1019	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ACBT_1020	COG0095	Lipoate-protein ligase
ACBT_1021	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACBT_1025	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ACBT_1026	COG0519	Catalyzes the synthesis of GMP from XMP
ACBT_1026	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACBT_1033	COG0596	Alpha beta hydrolase
ACBT_1035	COG0116	Belongs to the methyltransferase superfamily
ACBT_1035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACBT_1037	COG2989	Protein conserved in bacteria
ACBT_1042	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACBT_1046	COG0301	tRNA thio-modification
ACBT_1046	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACBT_1049	COG2814	Major facilitator Superfamily
ACBT_1052	COG2354	Protein conserved in bacteria
ACBT_1054	COG2081	HI0933 family
ACBT_1059	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACBT_1060	COG2171	N-acyltransferase activity
ACBT_1062	COG0488	(ABC) transporter
ACBT_1063	COG1944	ATP diphosphatase activity
ACBT_1065	COG2169	Transcriptional regulator
ACBT_1065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACBT_1066	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACBT_1068	COG0475	glutathione-regulated potassium exporter activity
ACBT_1068	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACBT_1070	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ACBT_1074	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACBT_1075	COG1611	Belongs to the LOG family
ACBT_1079	COG0217	transcriptional regulatory protein
ACBT_1085	COG1049	propionate catabolic process, 2-methylcitrate cycle
ACBT_1086	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACBT_1088	COG1451	nucleotide metabolic process
ACBT_1092	COG2884	Cell division ATP-binding protein ftsE
ACBT_1093	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACBT_1095	COG0564	pseudouridine synthase activity
ACBT_1096	COG0772	Belongs to the SEDS family
ACBT_1097	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ACBT_1098	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACBT_1099	COG3123	guanosine phosphorylase activity
ACBT_1102	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACBT_1103	COG0066	3-isopropylmalate dehydratase activity
ACBT_1104	COG0473	3-isopropylmalate dehydrogenase activity
ACBT_1107	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACBT_1108	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACBT_1109	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACBT_1110	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACBT_1111	COG0202	RNA polymerase activity
ACBT_1112	COG0203	ribosomal protein L17
ACBT_1113	COG0154	amidase activity
ACBT_1114	COG0516	GMP reductase activity
ACBT_1114	COG0517	IMP dehydrogenase activity
ACBT_1117	COG0840	transmembrane signaling receptor activity
ACBT_1118	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACBT_1119	COG0840	transmembrane signaling receptor activity
ACBT_1120	COG0754	glutathionylspermidine amidase activity
ACBT_1122	COG1119	ATPase activity
ACBT_1123	COG2076	Multidrug Resistance protein
ACBT_1129	COG4962	Type ii secretion system protein e
ACBT_1138	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACBT_1139	COG1881	PFAM PEBP family protein
ACBT_1140	COG0583	DNA-binding transcription factor activity
ACBT_1141	COG2855	membrane
ACBT_1145	COG1733	regulation of RNA biosynthetic process
ACBT_1146	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACBT_1148	COG0778	Nitroreductase
ACBT_1150	COG0488	(ABC) transporter
ACBT_1151	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACBT_1152	COG0702	epimerase
ACBT_1153	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACBT_1157	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACBT_1159	COG0784	Response regulator, receiver
ACBT_1159	COG3437	response regulator, receiver
ACBT_1160	COG1338	Plays a role in the flagellum-specific transport system
ACBT_1161	COG0768	penicillin binding
ACBT_1166	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACBT_1167	COG0322	excinuclease ABC activity
ACBT_1168	COG3201	nicotinamide mononucleotide transporter
ACBT_1169	COG2203	Gaf domain
ACBT_1169	COG3706	GGDEF domain
ACBT_1169	COG4251	negative regulation of phosphorylation
ACBT_1169	COG5001	Diguanylate cyclase
ACBT_1177	COG1741	Belongs to the pirin family
ACBT_1178	COG2205	protein histidine kinase activity
ACBT_1179	COG0745	RESPONSE REGULATOR receiver
ACBT_1184	COG0824	Thioesterase
ACBT_1186	COG0501	Belongs to the peptidase M48B family
ACBT_1187	COG1322	Protein conserved in bacteria
ACBT_1188	COG2321	neutral zinc metallopeptidase
ACBT_1190	COG0303	'Molybdopterin
ACBT_1192	COG0037	tRNA processing
ACBT_1194	COG3118	belongs to the thioredoxin family
ACBT_1197	COG4251	negative regulation of phosphorylation
ACBT_1197	COG2203	Gaf domain
ACBT_1197	COG3706	GGDEF domain
ACBT_1197	COG5001	Diguanylate cyclase
ACBT_1199	COG0248	Ppx GppA phosphatase
ACBT_1201	COG0028	Belongs to the TPP enzyme family
ACBT_1202	COG0440	acetolactate synthase activity
ACBT_1203	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACBT_1204	COG1196	nuclear chromosome segregation
ACBT_1204	COG1674	ftsk spoiiie
ACBT_1206	COG1114	Component of the transport system for branched-chain amino acids
ACBT_1207	COG0861	Integral membrane protein TerC family
ACBT_1209	COG0745	RESPONSE REGULATOR receiver
ACBT_1211	COG0113	porphobilinogen synthase activity
ACBT_1212	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACBT_1213	COG0357	Ribosomal RNA small subunit methyltransferase G
ACBT_1217	COG0751	glycine-tRNA ligase activity
ACBT_1218	COG0582	viral genome integration into host DNA
ACBT_1227	COG4796	Type ii and iii secretion system protein
ACBT_1231	COG1137	ATPase activity
ACBT_1233	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACBT_1235	COG0137	argininosuccinate synthase activity
ACBT_1236	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACBT_1237	COG1696	Membrane protein involved in D-alanine export
ACBT_1240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACBT_1245	COG0310	cobalt ion transport
ACBT_1248	COG0375	protein maturation
ACBT_1249	COG0309	Hydrogenase expression formation protein (HypE)
ACBT_1251	COG2084	Dehydrogenase
ACBT_1253	COG0298	carbon dioxide binding
ACBT_1254	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ACBT_1257	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ACBT_1261	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ACBT_1262	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ACBT_1267	COG0484	heat shock protein binding
ACBT_1271	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACBT_1272	COG3300	MHYT domain
ACBT_1272	COG5001	Diguanylate cyclase
ACBT_1273	COG5001	Diguanylate cyclase
ACBT_1273	COG4251	negative regulation of phosphorylation
ACBT_1273	COG3706	GGDEF domain
ACBT_1273	COG2203	Gaf domain
ACBT_1277	COG0166	Belongs to the GPI family
ACBT_1281	COG0708	Exodeoxyribonuclease III
ACBT_1282	COG0500	methyltransferase
ACBT_1283	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACBT_1283	COG1333	cytochrome c biogenesis protein
ACBT_1284	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACBT_1286	COG1193	negative regulation of DNA recombination
ACBT_1288	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACBT_1290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACBT_1291	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACBT_1293	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACBT_1296	COG0339	signal peptide processing
ACBT_1297	COG2890	protein-(glutamine-N5) methyltransferase activity
ACBT_1298	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACBT_1299	COG0494	nUDIX hydrolase
ACBT_1300	COG0527	aspartate kinase activity
ACBT_1303	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACBT_1304	COG1253	flavin adenine dinucleotide binding
ACBT_1306	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACBT_1310	COG2211	Major facilitator Superfamily
ACBT_1311	COG0300	oxidoreductase activity
ACBT_1312	COG0287	Prephenate dehydrogenase
ACBT_1313	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACBT_1314	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACBT_1315	COG0612	Peptidase, M16
ACBT_1316	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACBT_1321	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACBT_1323	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACBT_1323	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACBT_1326	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ACBT_1327	COG2201	protein-glutamate methylesterase activity
ACBT_1328	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ACBT_1329	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACBT_1331	COG0745	RESPONSE REGULATOR receiver
ACBT_1332	COG1185	polyribonucleotide nucleotidyltransferase activity
ACBT_1334	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ACBT_1338	COG1160	GTP binding
ACBT_1343	COG0039	L-malate dehydrogenase activity
ACBT_1348	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACBT_1348	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ACBT_1349	COG2201	protein-glutamate methylesterase activity
ACBT_1352	COG0484	heat shock protein binding
ACBT_1353	COG0789	Transcriptional regulator
ACBT_1357	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACBT_1358	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACBT_1359	COG1663	tetraacyldisaccharide 4'-kinase activity
ACBT_1360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACBT_1364	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACBT_1365	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ACBT_1366	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACBT_1367	COG0805	protein transport
ACBT_1368	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ACBT_1372	COG2181	nitrate reductase activity
ACBT_1372	COG0247	lactate metabolic process
ACBT_1373	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACBT_1376	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACBT_1376	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACBT_1377	COG3706	GGDEF domain
ACBT_1379	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ACBT_1382	COG0275	rRNA processing
ACBT_1384	COG0776	regulation of translation
ACBT_1390	COG4974	Belongs to the 'phage' integrase family
ACBT_1398	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACBT_1399	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACBT_1400	COG1722	exodeoxyribonuclease VII activity
ACBT_1401	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACBT_1404	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACBT_1405	COG0849	cell division
ACBT_1409	COG1393	Belongs to the ArsC family
ACBT_1413	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ACBT_1414	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ACBT_1415	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACBT_1422	COG0330	HflC and HflK could
ACBT_1425	COG0745	RESPONSE REGULATOR receiver
ACBT_1428	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACBT_1429	COG0788	formyltetrahydrofolate deformylase activity
ACBT_1432	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACBT_1439	COG0582	viral genome integration into host DNA
ACBT_1440	COG3706	GGDEF domain
ACBT_1442	COG0840	transmembrane signaling receptor activity
ACBT_1445	COG0513	Belongs to the DEAD box helicase family
ACBT_1446	COG0667	Aldo Keto reductase
ACBT_1450	COG2176	DNA-directed DNA polymerase activity
ACBT_1451	COG0135	phosphoribosylanthranilate isomerase activity
ACBT_1452	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACBT_1456	COG0642	Histidine kinase
ACBT_1457	COG0745	RESPONSE REGULATOR receiver
ACBT_1458	COG1666	GTP binding
ACBT_1459	COG2363	Small membrane protein
ACBT_1460	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ACBT_1466	COG0745	RESPONSE REGULATOR receiver
ACBT_1467	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACBT_1467	COG4191	Histidine kinase
ACBT_1468	COG0513	Belongs to the DEAD box helicase family
ACBT_1469	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACBT_1471	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACBT_1472	COG4206	TonB-dependent receptor
ACBT_1477	COG0546	phosphoglycolate phosphatase activity
ACBT_1478	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACBT_1479	COG0653	protein targeting
ACBT_1484	COG0642	Histidine kinase
ACBT_1485	COG0745	RESPONSE REGULATOR receiver
ACBT_1487	COG1132	(ABC) transporter
ACBT_1489	COG3300	MHYT domain
ACBT_1489	COG5001	Diguanylate cyclase
ACBT_1491	COG3040	lipid binding
ACBT_1492	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACBT_1493	COG3046	protein related to deoxyribodipyrimidine photolyase
ACBT_1496	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACBT_1498	COG2200	EAL domain
ACBT_1499	COG3279	Response regulator of the LytR AlgR family
ACBT_1500	COG3275	phosphorelay sensor kinase activity
ACBT_1501	COG1233	COG1233 Phytoene dehydrogenase and related
ACBT_1502	COG0415	Belongs to the DNA photolyase family
ACBT_1504	COG1090	epimerase
ACBT_1505	COG1472	Belongs to the glycosyl hydrolase 3 family
ACBT_1506	COG0484	heat shock protein binding
ACBT_1507	COG0484	heat shock protein binding
ACBT_1509	COG1607	acyl-coa hydrolase
ACBT_1510	COG0456	acetyltransferase
ACBT_1511	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ACBT_1514	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACBT_1515	COG0131	Imidazoleglycerol-phosphate dehydratase
ACBT_1516	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACBT_1517	COG0741	lytic transglycosylase activity
ACBT_1517	COG1388	LysM domain
ACBT_1518	COG0084	hydrolase, TatD family'
ACBT_1521	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ACBT_1522	COG0359	binds to the 23S rRNA
ACBT_1524	COG0163	prenyltransferase activity
ACBT_1525	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACBT_1526	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACBT_1527	COG0124	histidyl-tRNA synthetase
ACBT_1528	COG1166	arginine decarboxylase activity
ACBT_1529	COG1045	serine acetyltransferase
ACBT_1530	COG0730	response to heat
ACBT_1533	COG0488	(ABC) transporter
ACBT_1534	COG1610	YqeY-like protein
ACBT_1535	COG3706	GGDEF domain
ACBT_1536	COG0642	Histidine kinase
ACBT_1537	COG0745	RESPONSE REGULATOR receiver
ACBT_1539	COG3258	Cytochrome c
ACBT_1541	COG0300	oxidoreductase activity
ACBT_1542	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACBT_1543	COG0742	ribosomal rna small subunit methyltransferase
ACBT_1544	COG1418	mRNA catabolic process
ACBT_1545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACBT_1547	COG0552	protein localization to endoplasmic reticulum
ACBT_1550	COG1858	cytochrome C peroxidase
ACBT_1555	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACBT_1557	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACBT_1558	COG0735	belongs to the Fur family
ACBT_1560	COG0728	peptidoglycan biosynthetic process
ACBT_1561	COG1132	(ABC) transporter
ACBT_1562	COG0167	dihydroorotate dehydrogenase activity
ACBT_1564	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACBT_1565	COG1028	Short-chain dehydrogenase reductase Sdr
ACBT_1566	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACBT_1567	COG0750	zinc metalloprotease
ACBT_1568	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACBT_1569	COG1942	4-Oxalocrotonate Tautomerase
ACBT_1570	COG0583	DNA-binding transcription factor activity
ACBT_1571	COG0134	indole-3-glycerol-phosphate synthase activity
ACBT_1573	COG0727	PFAM Uncharacterised protein family (UPF0153)
ACBT_1574	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ACBT_1576	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACBT_1576	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACBT_1577	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACBT_1579	COG1979	alcohol dehydrogenase
ACBT_1580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ACBT_1582	COG0563	adenylate kinase activity
ACBT_1584	COG0563	adenylate kinase activity
ACBT_1586	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACBT_1588	COG1573	uracil-dna glycosylase
ACBT_1589	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACBT_1590	COG0024	Methionine aminopeptidase
ACBT_1591	COG0201	protein transport
ACBT_1592	COG0200	Binds to the 23S rRNA
ACBT_1593	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACBT_1594	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACBT_1595	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACBT_1596	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACBT_1597	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACBT_1598	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACBT_1599	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACBT_1600	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACBT_1601	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACBT_1602	COG0255	Belongs to the universal ribosomal protein uL29 family
ACBT_1603	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACBT_1604	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACBT_1605	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACBT_1606	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACBT_1607	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACBT_1608	COG0089	rRNA binding
ACBT_1609	COG0088	Forms part of the polypeptide exit tunnel
ACBT_1610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACBT_1611	COG0051	transcription antitermination factor activity, RNA binding
ACBT_1614	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACBT_1615	COG2267	carboxylic ester hydrolase activity
ACBT_1616	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACBT_1617	COG0632	four-way junction helicase activity
ACBT_1618	COG0840	transmembrane signaling receptor activity
ACBT_1620	COG0585	pseudouridine synthase activity
ACBT_1621	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACBT_1624	COG3123	guanosine phosphorylase activity
ACBT_1628	COG0012	GTP binding
ACBT_1629	COG1879	ABC-type sugar transport system periplasmic component
ACBT_1630	COG4191	Histidine kinase
ACBT_1630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACBT_1631	COG1966	Carbon starvation protein
ACBT_1638	COG4771	TonB-dependent receptor
ACBT_1639	COG3706	GGDEF domain
ACBT_1640	COG0577	efflux transmembrane transporter activity
ACBT_1640	COG1136	(ABC) transporter
ACBT_1641	COG0577	efflux transmembrane transporter activity
ACBT_1641	COG1136	(ABC) transporter
ACBT_1644	COG0811	peptide transport
ACBT_1645	COG0848	biopolymer transport protein
ACBT_1647	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACBT_1649	COG0133	tryptophan synthase activity
ACBT_1650	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACBT_1652	COG0305	Participates in initiation and elongation during chromosome replication
ACBT_1653	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ACBT_1656	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACBT_1657	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACBT_1659	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACBT_1660	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACBT_1661	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACBT_1663	COG0528	UMP kinase activity
ACBT_1664	COG1758	RNA polymerase activity
ACBT_1666	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACBT_1668	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACBT_1671	COG0193	aminoacyl-tRNA hydrolase activity
ACBT_1672	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ACBT_1673	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACBT_1674	COG0681	Belongs to the peptidase S26 family
ACBT_1675	COG0698	ribose 5-phosphate isomerase
ACBT_1683	COG0582	viral genome integration into host DNA
ACBT_1685	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACBT_1686	COG0556	nucleotide-excision repair
ACBT_1688	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACBT_1689	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACBT_1690	COG0784	Response regulator, receiver
ACBT_1690	COG0835	chemotaxis
ACBT_1691	COG0165	Argininosuccinate lyase
ACBT_1692	COG3706	GGDEF domain
ACBT_1693	COG2239	Acts as a magnesium transporter
ACBT_1694	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ACBT_1694	COG0822	iron-sulfur transferase activity
ACBT_1694	COG2906	2 iron, 2 sulfur cluster binding
ACBT_1695	COG0719	Fe-S assembly protein
ACBT_1696	COG0396	ATPase activity
ACBT_1698	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACBT_1699	COG2166	iron-sulfur cluster assembly
ACBT_1701	COG0439	Biotin carboxylase
ACBT_1703	COG0840	transmembrane signaling receptor activity
ACBT_1704	COG0840	transmembrane signaling receptor activity
ACBT_1708	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACBT_1709	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACBT_1710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACBT_1714	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACBT_1715	COG2814	Major facilitator Superfamily
ACBT_1718	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ACBT_1722	COG0525	valine-tRNA ligase activity
ACBT_1723	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACBT_1723	COG1648	precorrin-2 dehydrogenase activity
ACBT_1725	COG0252	asparaginase activity
ACBT_1726	COG1027	Aspartate ammonia-lyase
ACBT_1727	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACBT_1728	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACBT_1729	COG1047	Peptidyl-prolyl cis-trans
ACBT_1732	COG0823	Involved in the tonB-independent uptake of proteins
ACBT_1734	COG0848	biopolymer transport protein
ACBT_1735	COG0811	peptide transport
ACBT_1736	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ACBT_1737	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACBT_1738	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACBT_1739	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACBT_1740	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACBT_1741	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACBT_1743	COG1475	DNA binding
ACBT_1744	COG1192	Involved in chromosome partitioning
ACBT_1747	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACBT_1748	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACBT_1749	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACBT_1750	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACBT_1751	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ACBT_1752	COG0358	DNA primase activity
ACBT_1754	COG0571	ribonuclease III activity
ACBT_1755	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACBT_1757	COG2194	sulfuric ester hydrolase activity
ACBT_1758	COG0501	Belongs to the peptidase M48B family
ACBT_1762	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACBT_1764	COG0706	membrane insertase activity
ACBT_1765	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ACBT_1766	COG0594	ribonuclease P activity
ACBT_1767	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACBT_1768	COG0542	response to heat
ACBT_1769	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACBT_1770	COG2326	polyphosphate kinase activity
ACBT_1773	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACBT_1775	COG0494	nUDIX hydrolase
ACBT_1779	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACBT_1781	COG0739	heme binding
ACBT_1783	COG0598	Magnesium transport protein CorA
ACBT_1785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACBT_1787	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACBT_1795	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACBT_1796	COG1858	cytochrome C peroxidase
ACBT_1802	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACBT_1809	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACBT_1811	COG1692	metallophosphoesterase
ACBT_1813	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACBT_1815	COG0840	transmembrane signaling receptor activity
ACBT_1816	COG2081	HI0933 family
ACBT_1817	COG0642	Histidine kinase
ACBT_1818	COG0745	RESPONSE REGULATOR receiver
ACBT_1820	COG2203	Gaf domain
ACBT_1820	COG3706	GGDEF domain
ACBT_1820	COG4251	negative regulation of phosphorylation
ACBT_1820	COG5001	Diguanylate cyclase
ACBT_1825	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACBT_1832	COG0285	dihydrofolate synthase activity
ACBT_1834	COG0495	leucyl-tRNA aminoacylation
ACBT_1836	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACBT_1837	COG1360	Flagellar Motor Protein
ACBT_1840	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACBT_1841	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACBT_1842	COG1862	Preprotein translocase
ACBT_1843	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ACBT_1846	COG0617	tRNA 3'-terminal CCA addition
ACBT_1847	COG0668	transmembrane transport
ACBT_1848	COG0442	prolyl-tRNA aminoacylation
ACBT_1849	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACBT_1850	COG0142	geranyltranstransferase activity
ACBT_1852	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACBT_1853	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACBT_1855	COG0811	peptide transport
ACBT_1856	COG0848	biopolymer transport protein
ACBT_1857	COG0191	fructose-bisphosphate aldolase activity
ACBT_1858	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACBT_1859	COG0745	RESPONSE REGULATOR receiver
ACBT_1860	COG0642	Histidine kinase
ACBT_1861	COG1832	CoA-binding protein
ACBT_1862	COG2404	hydrolase activity, acting on ester bonds
ACBT_1864	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACBT_1865	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACBT_1866	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACBT_1868	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACBT_1870	COG0243	molybdopterin cofactor binding
ACBT_1871	COG0437	4 iron, 4 sulfur cluster binding
ACBT_1872	COG0348	domain, Protein
ACBT_1873	COG3043	anaerobic respiration
ACBT_1877	COG0840	transmembrane signaling receptor activity
ACBT_1878	COG5001	Diguanylate cyclase
ACBT_1878	COG5002	protein histidine kinase activity
ACBT_1880	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACBT_1882	COG3204	pilus organization
ACBT_1884	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACBT_1885	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ACBT_1887	COG3610	response to peptide
ACBT_1888	COG3610	response to peptide
ACBT_1889	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ACBT_1890	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACBT_1891	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACBT_1892	COG0649	NAD binding
ACBT_1892	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACBT_1893	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ACBT_1895	COG0372	Belongs to the citrate synthase family
ACBT_1896	COG1034	ATP synthesis coupled electron transport
ACBT_1897	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACBT_1898	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACBT_1899	COG0839	Belongs to the complex I subunit 6 family
ACBT_1900	COG0713	ATP synthesis coupled electron transport
ACBT_1901	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACBT_1903	COG1007	ATP synthesis coupled electron transport
ACBT_1905	COG1053	succinate dehydrogenase
ACBT_1906	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACBT_1909	COG2824	Alkylphosphonate utilization operon protein PhnA
ACBT_1915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACBT_1917	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ACBT_1919	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACBT_1920	COG2828	Protein conserved in bacteria
ACBT_1921	COG1335	isochorismatase
ACBT_1922	COG0181	hydroxymethylbilane synthase activity
ACBT_1924	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACBT_1925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACBT_1926	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACBT_1927	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACBT_1928	COG0450	alkyl hydroperoxide reductase
ACBT_1930	COG0105	UTP biosynthetic process
ACBT_1932	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACBT_1933	COG0416	fatty acid biosynthetic process
ACBT_1934	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACBT_1938	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACBT_1939	COG0540	Belongs to the ATCase OTCase family
ACBT_1941	COG4773	Receptor
ACBT_1943	COG1706	bacterial-type flagellum-dependent cell motility
ACBT_1950	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ACBT_1952	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ACBT_1955	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACBT_1957	COG0288	reversible hydration of carbon dioxide
ACBT_1958	COG0156	8-amino-7-oxononanoate synthase activity
ACBT_1962	COG2885	chlorophyll binding
ACBT_1967	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACBT_1968	COG0587	DNA-directed DNA polymerase activity
ACBT_1972	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACBT_1972	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ACBT_1973	COG0504	CTP synthase activity
ACBT_1974	COG0348	domain, Protein
ACBT_1976	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACBT_1978	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ACBT_1980	COG0157	Belongs to the NadC ModD family
ACBT_1981	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ACBT_1983	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ACBT_1985	COG0083	homoserine kinase activity
ACBT_1987	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACBT_1988	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACBT_1989	COG0779	Required for maturation of 30S ribosomal subunits
ACBT_1990	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACBT_1990	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACBT_1992	COG2121	Domain of unknown function (DUF374)
ACBT_1993	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACBT_1995	COG0195	Participates in both transcription termination and antitermination
ACBT_1996	COG0215	cysteine-tRNA ligase activity
ACBT_1997	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACBT_1998	COG0629	single-stranded DNA binding
ACBT_1999	COG0360	Binds together with S18 to 16S ribosomal RNA
ACBT_2002	COG0557	exoribonuclease II activity
ACBT_2003	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACBT_2009	COG0343	queuine tRNA-ribosyltransferase activity
ACBT_2010	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACBT_2011	COG1393	Belongs to the ArsC family
ACBT_2012	COG3248	Nucleoside-binding outer membrane protein
ACBT_2013	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ACBT_2015	COG0560	Phosphoserine phosphatase
ACBT_2017	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACBT_2019	COG0736	holo-[acyl-carrier-protein] synthase activity
ACBT_2021	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACBT_2022	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACBT_2025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACBT_2027	COG0418	dihydroorotase activity
ACBT_2029	COG0004	ammonium transporteR
ACBT_2031	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ACBT_2033	COG1301	dicarboxylic acid transport
ACBT_2039	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACBT_2044	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACBT_2046	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACBT_2050	COG4191	Histidine kinase
ACBT_2052	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACBT_2058	COG0840	transmembrane signaling receptor activity
ACBT_2062	COG0511	ligase activity, forming carbon-carbon bonds
ACBT_2069	COG2022	thiamine diphosphate biosynthetic process
ACBT_2071	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACBT_2071	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACBT_2073	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACBT_2076	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACBT_2077	COG0575	Belongs to the CDS family
ACBT_2082	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACBT_2084	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ACBT_2085	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACBT_2088	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACBT_2089	COG0746	molybdenum cofactor guanylyltransferase activity
ACBT_2090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACBT_2091	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACBT_2092	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACBT_2093	COG0268	Binds directly to 16S ribosomal RNA
ACBT_2094	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACBT_2095	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACBT_2096	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACBT_2097	COG0573	inorganic phosphate transmembrane transporter activity
ACBT_2098	COG0581	inorganic phosphate transmembrane transporter activity
ACBT_2099	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACBT_2100	COG0704	Plays a role in the regulation of phosphate uptake
ACBT_2102	COG0745	RESPONSE REGULATOR receiver
ACBT_2103	COG2205	protein histidine kinase activity
ACBT_2104	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACBT_2105	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACBT_2106	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACBT_2108	COG0352	thiamine-phosphate diphosphorylase activity
ACBT_2108	COG0351	phosphomethylpyrimidine kinase
ACBT_2110	COG0546	phosphoglycolate phosphatase activity
ACBT_2115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACBT_2116	COG1854	S-ribosylhomocysteine lyase activity
ACBT_2118	COG1686	Belongs to the peptidase S11 family
ACBT_2120	COG0505	Belongs to the CarA family
ACBT_2122	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACBT_2123	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ACBT_2124	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACBT_2127	COG2353	YceI-like domain
ACBT_2131	COG0460	homoserine dehydrogenase
ACBT_2132	COG0436	Aminotransferase
ACBT_2134	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACBT_2135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ACBT_2136	COG0254	rRNA binding
ACBT_2137	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACBT_2143	COG4974	Belongs to the 'phage' integrase family
ACBT_2144	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACBT_2150	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACBT_2152	COG0367	asparagine synthase
ACBT_2154	COG0562	UDP-galactopyranose mutase
ACBT_2155	COG2244	polysaccharide biosynthetic process
ACBT_2156	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACBT_2157	COG1088	dTDP-glucose 4,6-dehydratase activity
ACBT_2168	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACBT_2170	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACBT_2194	COG1484	DNA-dependent DNA replication
ACBT_2195	COG4584	PFAM Integrase catalytic
ACBT_2197	COG3550	peptidyl-serine autophosphorylation
ACBT_2204	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACBT_2206	COG1696	Membrane protein involved in D-alanine export
ACBT_2215	COG1294	oxidase, subunit
ACBT_2216	COG1271	oxidase subunit
ACBT_2218	COG1342	Belongs to the UPF0251 family
ACBT_2238	COG0237	dephospho-CoA kinase activity
ACBT_2239	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACBT_2241	COG1410	methionine synthase
ACBT_2241	COG0646	methionine synthase
ACBT_2243	COG0803	Belongs to the bacterial solute-binding protein 9 family
ACBT_2245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACBT_2250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACBT_2250	COG0140	phosphoribosyl-ATP diphosphatase activity
ACBT_2252	COG0489	protein tyrosine kinase activity
ACBT_2255	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACBT_2255	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACBT_2256	COG0745	RESPONSE REGULATOR receiver
ACBT_2257	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACBT_2258	COG2353	YceI-like domain
ACBT_2259	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACBT_2264	COG0642	Histidine kinase
ACBT_2265	COG0745	RESPONSE REGULATOR receiver
ACBT_2266	COG0724	RNA recognition motif
ACBT_2267	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACBT_2268	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACBT_2271	COG0107	imidazoleglycerol-phosphate synthase activity
ACBT_2272	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACBT_2274	COG0517	IMP dehydrogenase activity
ACBT_2274	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ACBT_2275	COG1187	pseudouridine synthase activity
ACBT_2276	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACBT_2276	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ACBT_2277	COG1981	membrane
ACBT_2278	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACBT_2280	COG0367	asparagine synthase
ACBT_2282	COG0306	phosphate transporter
ACBT_2283	COG0513	Belongs to the DEAD box helicase family
ACBT_2284	COG0439	Biotin carboxylase
ACBT_2285	COG0511	ligase activity, forming carbon-carbon bonds
ACBT_2286	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACBT_2286	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACBT_2288	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACBT_2289	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACBT_2290	COG0604	alcohol dehydrogenase
ACBT_2293	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACBT_2294	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACBT_2295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACBT_2296	COG0564	pseudouridine synthase activity
ACBT_2298	COG2860	membrane
ACBT_2299	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ACBT_2300	COG3706	GGDEF domain
ACBT_2301	COG0642	Histidine kinase
ACBT_2302	COG0745	RESPONSE REGULATOR receiver
ACBT_2310	COG0425	Belongs to the sulfur carrier protein TusA family
ACBT_2312	COG1217	gtp-binding protein TYPA
ACBT_2313	COG1959	2 iron, 2 sulfur cluster binding
ACBT_2314	COG2199	diguanylate cyclase activity
ACBT_2314	COG3287	FIST C domain
ACBT_2314	COG2200	EAL domain
ACBT_2315	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACBT_2316	COG4208	sulfate ABC transporter
ACBT_2319	COG1408	metallophosphoesterase
ACBT_2320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACBT_2322	COG0133	tryptophan synthase activity
ACBT_2325	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ACBT_2326	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD