locus-tag	class	description
NGX11_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NGX11_00010	COG0592	DNA-directed DNA polymerase activity
NGX11_00015	COG0187	DNA topoisomerase II activity
NGX11_00020	COG0492	ferredoxin-NADP+ reductase activity
NGX11_00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NGX11_00040	COG0500	methyltransferase
NGX11_00045	COG3842	ATPase activity
NGX11_00110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NGX11_00120	COG0840	transmembrane signaling receptor activity
NGX11_00125	COG0840	transmembrane signaling receptor activity
NGX11_00130	COG2081	HI0933 family
NGX11_00155	COG1959	2 iron, 2 sulfur cluster binding
NGX11_00175	COG0175	sulfate reduction
NGX11_00180	COG2895	sulfate adenylyltransferase (ATP) activity
NGX11_00190	COG2814	Major facilitator Superfamily
NGX11_00195	COG0783	Belongs to the Dps family
NGX11_00200	COG0546	phosphoglycolate phosphatase activity
NGX11_00210	COG1012	belongs to the aldehyde dehydrogenase family
NGX11_00215	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NGX11_00230	COG3022	response to hydroperoxide
NGX11_00250	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NGX11_00255	COG0233	cytoplasmic translational termination
NGX11_00260	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NGX11_00270	COG0352	thiamine-phosphate diphosphorylase activity
NGX11_00275	COG0670	Belongs to the BI1 family
NGX11_00305	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NGX11_00325	COG1459	type II secretion system
NGX11_00330	COG0598	Magnesium transport protein CorA
NGX11_00345	COG1178	ABC-type Fe3 transport system permease component
NGX11_00350	COG1840	ABC-type Fe3 transport system, periplasmic component
NGX11_00405	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NGX11_00410	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NGX11_00415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NGX11_00420	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NGX11_00425	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NGX11_00430	COG1077	Cell shape determining protein MreB Mrl
NGX11_00445	COG0445	tRNA wobble uridine modification
NGX11_00510	COG0037	tRNA processing
NGX11_00550	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NGX11_00555	COG4221	oxidoreductase activity
NGX11_00560	COG0659	secondary active sulfate transmembrane transporter activity
NGX11_00575	COG1222	aaa ATPase
NGX11_00585	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NGX11_00590	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NGX11_00610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NGX11_00615	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NGX11_00630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NGX11_00645	COG2089	acid synthase
NGX11_00650	COG4804	nuclease activity
NGX11_00655	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NGX11_00685	COG0028	Belongs to the TPP enzyme family
NGX11_00690	COG4569	acetaldehyde dehydrogenase (acetylating) activity
NGX11_00695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NGX11_00700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NGX11_00705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NGX11_00740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NGX11_00755	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NGX11_00765	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NGX11_00770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NGX11_00775	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NGX11_00790	COG0101	tRNA pseudouridine synthase activity
NGX11_00800	COG1420	regulation of RNA biosynthetic process
NGX11_00805	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NGX11_00810	COG0443	Heat shock 70 kDa protein
NGX11_00830	COG2121	Domain of unknown function (DUF374)
NGX11_00835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NGX11_00845	COG0195	Participates in both transcription termination and antitermination
NGX11_00850	COG0215	cysteine-tRNA ligase activity
NGX11_00855	COG1393	Belongs to the ArsC family
NGX11_00860	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NGX11_00865	COG0343	queuine tRNA-ribosyltransferase activity
NGX11_00895	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NGX11_00900	COG0557	exoribonuclease II activity
NGX11_00910	COG1466	dna polymerase III delta subunit
NGX11_00915	COG0360	Binds together with S18 to 16S ribosomal RNA
NGX11_00920	COG0629	single-stranded DNA binding
NGX11_00925	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NGX11_00935	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NGX11_00950	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NGX11_00960	COG0157	Belongs to the NadC ModD family
NGX11_00975	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NGX11_00985	COG0083	homoserine kinase activity
NGX11_00995	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NGX11_01000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NGX11_01005	COG0779	Required for maturation of 30S ribosomal subunits
NGX11_01010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NGX11_01010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NGX11_01015	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NGX11_01020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NGX11_01025	COG1185	polyribonucleotide nucleotidyltransferase activity
NGX11_01025	COG0539	negative regulation of cytoplasmic translation
NGX11_01030	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NGX11_01035	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NGX11_01040	COG0072	phenylalanine-tRNA ligase activity
NGX11_01040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NGX11_01045	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NGX11_01050	COG0537	adenosine 5'-monophosphoramidase activity
NGX11_01055	COG0825	malonyl-CoA metabolic process
NGX11_01060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NGX11_01065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NGX11_01075	COG0602	queuosine metabolic process
NGX11_01085	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NGX11_01105	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NGX11_01115	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NGX11_01120	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NGX11_01125	COG1074	ATP-dependent DNA helicase activity
NGX11_01135	COG0356	it plays a direct role in the translocation of protons across the membrane
NGX11_01140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NGX11_01145	COG0191	fructose-bisphosphate aldolase activity
NGX11_01155	COG0745	RESPONSE REGULATOR receiver
NGX11_01160	COG0642	Histidine kinase
NGX11_01185	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NGX11_01195	COG3287	FIST C domain
NGX11_01195	COG2200	EAL domain
NGX11_01195	COG2199	diguanylate cyclase activity
NGX11_01215	COG3043	anaerobic respiration
NGX11_01220	COG0348	domain, Protein
NGX11_01225	COG0437	4 iron, 4 sulfur cluster binding
NGX11_01230	COG0243	molybdopterin cofactor binding
NGX11_01255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NGX11_01260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NGX11_01265	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NGX11_01275	COG2404	hydrolase activity, acting on ester bonds
NGX11_01285	COG0840	transmembrane signaling receptor activity
NGX11_01310	COG2030	dehydratase
NGX11_01330	COG1401	restriction endodeoxyribonuclease activity
NGX11_01340	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NGX11_01345	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NGX11_01350	COG0542	response to heat
NGX11_01385	COG0148	phosphopyruvate hydratase activity
NGX11_01400	COG2814	Major facilitator Superfamily
NGX11_01410	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NGX11_01415	COG0049	tRNA binding
NGX11_01420	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NGX11_01425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NGX11_01430	COG0497	DNA recombination
NGX11_01435	COG0840	transmembrane signaling receptor activity
NGX11_01440	COG0826	peptidase U32
NGX11_01450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NGX11_01460	COG0752	glycyl-tRNA synthetase alpha subunit
NGX11_01465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NGX11_01475	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NGX11_01475	COG1519	Transferase
NGX11_01480	COG0564	pseudouridine synthase activity
NGX11_01485	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NGX11_01490	COG0228	four-way junction DNA binding
NGX11_01495	COG1837	Belongs to the UPF0109 family
NGX11_01500	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NGX11_01520	COG0745	RESPONSE REGULATOR receiver
NGX11_01530	COG4786	Flagellar basal body rod
NGX11_01535	COG1815	bacterial-type flagellum-dependent cell motility
NGX11_01540	COG1766	The M ring may be actively involved in energy transduction
NGX11_01545	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NGX11_01555	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NGX11_01565	COG1749	Flagellar hook protein flgE
NGX11_01570	COG1749	Flagellar hook protein flgE
NGX11_01595	COG3951	Flagellar rod assembly protein muramidase FlgJ
NGX11_01610	COG1419	protein localization to endoplasmic reticulum
NGX11_01615	COG0455	bacterial-type flagellum organization
NGX11_01645	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NGX11_01655	COG1157	protein secretion by the type III secretion system
NGX11_01665	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NGX11_01675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NGX11_01690	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NGX11_01700	COG0336	Belongs to the RNA methyltransferase TrmD family
NGX11_01705	COG0335	large ribosomal subunit rRNA binding
NGX11_01710	COG0586	Pfam SNARE associated Golgi protein
NGX11_01715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NGX11_01740	COG0251	oxidation-reduction process
NGX11_01745	COG3610	response to peptide
NGX11_01750	COG2966	Psort location CytoplasmicMembrane, score
NGX11_01765	COG0811	peptide transport
NGX11_01780	COG1971	Probably functions as a manganese efflux pump
NGX11_01805	COG0628	permease
NGX11_01815	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NGX11_01820	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NGX11_01835	COG4773	Receptor
NGX11_01840	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NGX11_01845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NGX11_01855	COG0142	geranyltranstransferase activity
NGX11_01860	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NGX11_01865	COG0442	prolyl-tRNA aminoacylation
NGX11_01870	COG0668	transmembrane transport
NGX11_01880	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NGX11_01885	COG1862	Preprotein translocase
NGX11_01890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NGX11_01895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NGX11_01910	COG1360	Flagellar Motor Protein
NGX11_01915	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NGX11_01925	COG0495	leucyl-tRNA aminoacylation
NGX11_01935	COG0285	dihydrofolate synthase activity
NGX11_01960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NGX11_01975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NGX11_01985	COG0077	Prephenate dehydratase
NGX11_01985	COG1605	Chorismate mutase
NGX11_01990	COG0454	-acetyltransferase
NGX11_02030	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NGX11_02035	COG0444	Belongs to the ABC transporter superfamily
NGX11_02040	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NGX11_02045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NGX11_02075	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NGX11_02080	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NGX11_02095	COG0250	Participates in transcription elongation, termination and antitermination
NGX11_02100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NGX11_02105	COG0081	regulation of translation
NGX11_02110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NGX11_02115	COG0222	ribosome binding
NGX11_02120	COG0085	RNA polymerase activity
NGX11_02125	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NGX11_02145	COG0386	Belongs to the glutathione peroxidase family
NGX11_02150	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
NGX11_02155	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
NGX11_02175	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NGX11_02190	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NGX11_02195	COG0298	carbon dioxide binding
NGX11_02200	COG0409	Hydrogenase expression formation protein
NGX11_02205	COG4804	nuclease activity
NGX11_02215	COG0309	Hydrogenase expression formation protein (HypE)
NGX11_02230	COG0310	cobalt ion transport
NGX11_02255	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NGX11_02265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NGX11_02275	COG1295	ribonuclease BN
NGX11_02280	COG0277	FAD linked oxidase domain protein
NGX11_02290	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NGX11_02295	COG2226	methyltransferase
NGX11_02300	COG0196	riboflavin kinase activity
NGX11_02345	COG1739	Uncharacterized protein family UPF0029
NGX11_02365	COG0483	inositol monophosphate 1-phosphatase activity
NGX11_02370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NGX11_02410	COG0438	transferase activity, transferring glycosyl groups
NGX11_02415	COG0438	transferase activity, transferring glycosyl groups
NGX11_02430	COG0463	Glycosyl transferase, family 2
NGX11_02435	COG0859	PFAM glycosyl transferase family 9
NGX11_02450	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NGX11_02455	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NGX11_02455	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NGX11_02465	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NGX11_02475	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NGX11_02485	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NGX11_02500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NGX11_02510	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NGX11_02560	COG1136	(ABC) transporter
NGX11_02575	COG2353	YceI-like domain
NGX11_02585	COG1408	metallophosphoesterase
NGX11_02600	COG1121	(ABC) transporter
NGX11_02605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NGX11_02610	COG2996	Protein conserved in bacteria
NGX11_02615	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NGX11_02635	COG0525	valine-tRNA ligase activity
NGX11_02670	COG2814	Major facilitator Superfamily
NGX11_02675	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NGX11_02695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NGX11_02705	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NGX11_02710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NGX11_02720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NGX11_02740	COG0439	Biotin carboxylase
NGX11_02750	COG2166	iron-sulfur cluster assembly
NGX11_02755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NGX11_02765	COG0396	ATPase activity
NGX11_02770	COG0719	Fe-S assembly protein
NGX11_02785	COG3706	GGDEF domain
NGX11_02790	COG0165	Argininosuccinate lyase
NGX11_02795	COG0556	nucleotide-excision repair
NGX11_02805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NGX11_02810	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NGX11_02815	COG0835	chemotaxis
NGX11_02815	COG0784	Response regulator, receiver
NGX11_02830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NGX11_02835	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NGX11_02840	COG0585	pseudouridine synthase activity
NGX11_02850	COG0840	transmembrane signaling receptor activity
NGX11_02855	COG0632	four-way junction helicase activity
NGX11_02860	COG1181	Belongs to the D-alanine--D-alanine ligase family
NGX11_02870	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NGX11_02895	COG0284	orotidine-5'-phosphate decarboxylase activity
NGX11_02900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NGX11_02905	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NGX11_02920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NGX11_02920	COG0189	ligase activity
NGX11_02935	COG2205	protein histidine kinase activity
NGX11_02935	COG0784	Response regulator, receiver
NGX11_02940	COG4251	negative regulation of phosphorylation
NGX11_02945	COG0174	glutamine synthetase
NGX11_02955	COG0314	molybdopterin synthase activity
NGX11_02965	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NGX11_02970	COG1968	undecaprenyl-diphosphatase activity
NGX11_02990	COG0772	Belongs to the SEDS family
NGX11_02995	COG0768	penicillin binding
NGX11_03000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NGX11_03005	COG1858	cytochrome C peroxidase
NGX11_03035	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NGX11_03050	COG1116	anion transmembrane transporter activity
NGX11_03055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NGX11_03070	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NGX11_03080	COG2204	response regulator
NGX11_03090	COG3706	GGDEF domain
NGX11_03090	COG4251	negative regulation of phosphorylation
NGX11_03090	COG5001	Diguanylate cyclase
NGX11_03090	COG2203	Gaf domain
NGX11_03100	COG0745	RESPONSE REGULATOR receiver
NGX11_03105	COG0642	Histidine kinase
NGX11_03110	COG2081	HI0933 family
NGX11_03115	COG0840	transmembrane signaling receptor activity
NGX11_03125	COG3920	Histidine kinase
NGX11_03130	COG5002	protein histidine kinase activity
NGX11_03135	COG1692	metallophosphoesterase
NGX11_03155	COG1570	exodeoxyribonuclease VII activity
NGX11_03160	COG0835	chemotaxis
NGX11_03170	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NGX11_03175	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NGX11_03185	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NGX11_03190	COG0459	protein refolding
NGX11_03200	COG1686	Belongs to the peptidase S11 family
NGX11_03215	COG0848	biopolymer transport protein
NGX11_03220	COG0811	peptide transport
NGX11_03235	COG1136	(ABC) transporter
NGX11_03240	COG0577	efflux transmembrane transporter activity
NGX11_03240	COG1136	(ABC) transporter
NGX11_03245	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NGX11_03250	COG0542	response to heat
NGX11_03255	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NGX11_03265	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NGX11_03270	COG0706	membrane insertase activity
NGX11_03280	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NGX11_03300	COG3706	GGDEF domain
NGX11_03310	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NGX11_03315	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NGX11_03320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NGX11_03330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NGX11_03335	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NGX11_03350	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NGX11_03355	COG0305	Participates in initiation and elongation during chromosome replication
NGX11_03360	COG2165	general secretion pathway protein
NGX11_03370	COG0673	inositol 2-dehydrogenase activity
NGX11_03375	COG4771	TonB-dependent receptor
NGX11_03395	COG1966	Carbon starvation protein
NGX11_03400	COG0563	adenylate kinase activity
NGX11_03405	COG0563	adenylate kinase activity
NGX11_03415	COG3706	GGDEF domain
NGX11_03420	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NGX11_03425	COG1979	alcohol dehydrogenase
NGX11_03430	COG0840	transmembrane signaling receptor activity
NGX11_03435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NGX11_03440	COG0322	excinuclease ABC activity
NGX11_03445	COG0840	transmembrane signaling receptor activity
NGX11_03470	COG0745	RESPONSE REGULATOR receiver
NGX11_03505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NGX11_03515	COG0784	Response regulator, receiver
NGX11_03515	COG3437	response regulator, receiver
NGX11_03520	COG1338	Plays a role in the flagellum-specific transport system
NGX11_03525	COG0768	penicillin binding
NGX11_03545	COG2884	Cell division ATP-binding protein ftsE
NGX11_03550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NGX11_03560	COG0564	pseudouridine synthase activity
NGX11_03565	COG0772	Belongs to the SEDS family
NGX11_03575	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NGX11_03580	COG3123	guanosine phosphorylase activity
NGX11_03660	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NGX11_03665	COG0475	glutathione-regulated potassium exporter activity
NGX11_03665	COG0569	domain protein
NGX11_03670	COG0210	DNA helicase
NGX11_03675	COG0709	Synthesizes selenophosphate from selenide and ATP
NGX11_03680	COG1305	Transglutaminase-like
NGX11_03700	COG2204	response regulator
NGX11_03735	COG0437	4 iron, 4 sulfur cluster binding
NGX11_03745	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NGX11_03765	COG0303	'Molybdopterin
NGX11_03770	COG2998	abc-type tungstate transport system, permease component
NGX11_03775	COG4662	Binding-protein-dependent transport system inner membrane component
NGX11_03795	COG2814	Major facilitator Superfamily
NGX11_03805	COG2354	Protein conserved in bacteria
NGX11_03810	COG0726	polysaccharide deacetylase
NGX11_03815	COG2081	HI0933 family
NGX11_03820	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NGX11_03830	COG4804	nuclease activity
NGX11_03845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NGX11_03870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NGX11_03925	COG1525	nuclease
NGX11_03945	COG2171	N-acyltransferase activity
NGX11_03950	COG1944	ATP diphosphatase activity
NGX11_03955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NGX11_03955	COG2169	Transcriptional regulator
NGX11_03960	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NGX11_04005	COG0628	permease
NGX11_04010	COG2255	four-way junction helicase activity
NGX11_04015	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NGX11_04020	COG0159	tryptophan synthase activity
NGX11_04025	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NGX11_04035	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NGX11_04050	COG0137	argininosuccinate synthase activity
NGX11_04055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NGX11_04060	COG0742	ribosomal rna small subunit methyltransferase
NGX11_04065	COG1418	mRNA catabolic process
NGX11_04080	COG0552	protein localization to endoplasmic reticulum
NGX11_04100	COG2249	NAD(P)H dehydrogenase (quinone) activity
NGX11_04105	COG1902	pentaerythritol trinitrate reductase activity
NGX11_04110	COG0778	Nitroreductase
NGX11_04120	COG0488	(ABC) transporter
NGX11_04125	COG1607	acyl-coa hydrolase
NGX11_04130	COG0840	transmembrane signaling receptor activity
NGX11_04140	COG0484	heat shock protein binding
NGX11_04145	COG0484	heat shock protein binding
NGX11_04165	COG0300	oxidoreductase activity
NGX11_04175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NGX11_04180	COG0802	atpase or kinase
NGX11_04185	COG1137	ATPase activity
NGX11_04190	COG1686	Belongs to the peptidase S11 family
NGX11_04210	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NGX11_04220	COG2201	protein-glutamate methylesterase activity
NGX11_04235	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NGX11_04280	COG2076	Multidrug Resistance protein
NGX11_04285	COG0642	Histidine kinase
NGX11_04290	COG0745	RESPONSE REGULATOR receiver
NGX11_04300	COG3258	Cytochrome c
NGX11_04310	COG1049	propionate catabolic process, 2-methylcitrate cycle
NGX11_04315	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NGX11_04320	COG2363	Small membrane protein
NGX11_04325	COG1666	GTP binding
NGX11_04360	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NGX11_04375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NGX11_04375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NGX11_04385	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NGX11_04410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NGX11_04415	COG0612	Peptidase, M16
NGX11_04420	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NGX11_04425	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NGX11_04430	COG0287	Prephenate dehydrogenase
NGX11_04445	COG0243	molybdopterin cofactor binding
NGX11_04455	COG1921	L-seryl-tRNASec selenium transferase activity
NGX11_04465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NGX11_04470	COG0135	phosphoribosylanthranilate isomerase activity
NGX11_04475	COG2176	DNA-directed DNA polymerase activity
NGX11_04485	COG1013	pyruvate-flavodoxin oxidoreductase activity
NGX11_04490	COG0674	pyruvate-flavodoxin oxidoreductase activity
NGX11_04490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NGX11_04500	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NGX11_04505	COG0727	PFAM Uncharacterised protein family (UPF0153)
NGX11_04515	COG0134	indole-3-glycerol-phosphate synthase activity
NGX11_04520	COG1942	4-Oxalocrotonate Tautomerase
NGX11_04525	COG2199	diguanylate cyclase activity
NGX11_04535	COG0739	heme binding
NGX11_04540	COG1610	YqeY-like protein
NGX11_04545	COG0488	(ABC) transporter
NGX11_04550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NGX11_04570	COG0667	Aldo Keto reductase
NGX11_04575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NGX11_04580	COG0805	protein transport
NGX11_04585	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NGX11_04595	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NGX11_04610	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NGX11_04615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NGX11_04620	COG1663	tetraacyldisaccharide 4'-kinase activity
NGX11_04625	COG0861	Integral membrane protein TerC family
NGX11_04630	COG0789	Transcriptional regulator
NGX11_04635	COG0484	heat shock protein binding
NGX11_04640	COG4191	Histidine kinase
NGX11_04650	COG2201	protein-glutamate methylesterase activity
NGX11_04670	COG0776	regulation of translation
NGX11_04680	COG0275	rRNA processing
NGX11_04710	COG0039	L-malate dehydrogenase activity
NGX11_04720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NGX11_04730	COG1193	negative regulation of DNA recombination
NGX11_04735	COG1253	flavin adenine dinucleotide binding
NGX11_04745	COG1119	ATPase activity
NGX11_04755	COG2258	MOSC domain
NGX11_04760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NGX11_04770	COG3135	benzoate transporter
NGX11_04780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NGX11_04785	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NGX11_04790	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NGX11_04790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NGX11_04805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NGX11_04820	COG0527	aspartate kinase activity
NGX11_04825	COG0494	nUDIX hydrolase
NGX11_04830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NGX11_04835	COG2890	protein-(glutamine-N5) methyltransferase activity
NGX11_04840	COG0339	signal peptide processing
NGX11_04855	COG0824	Thioesterase
NGX11_04860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NGX11_04865	COG0501	Belongs to the peptidase M48B family
NGX11_04875	COG2321	neutral zinc metallopeptidase
NGX11_04895	COG0037	tRNA processing
NGX11_04930	COG0028	Belongs to the TPP enzyme family
NGX11_04935	COG0440	acetolactate synthase activity
NGX11_04940	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NGX11_04945	COG1674	ftsk spoiiie
NGX11_04945	COG1196	nuclear chromosome segregation
NGX11_04950	COG1028	Short-chain dehydrogenase reductase Sdr
NGX11_04960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NGX11_04965	COG1160	GTP binding
NGX11_04970	COG0659	secondary active sulfate transmembrane transporter activity
NGX11_04990	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NGX11_05000	COG1185	polyribonucleotide nucleotidyltransferase activity
NGX11_05005	COG0745	RESPONSE REGULATOR receiver
NGX11_05010	COG0643	Histidine kinase
NGX11_05010	COG2198	Histidine kinase
NGX11_05015	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NGX11_05025	COG2201	protein-glutamate methylesterase activity
NGX11_05030	COG0582	viral genome integration into host DNA
NGX11_05035	COG0484	heat shock protein binding
NGX11_05060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NGX11_05070	COG3706	GGDEF domain
NGX11_05070	COG5001	Diguanylate cyclase
NGX11_05070	COG4251	negative regulation of phosphorylation
NGX11_05070	COG2203	Gaf domain
NGX11_05075	COG0500	methyltransferase
NGX11_05085	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NGX11_05085	COG1333	cytochrome c biogenesis protein
NGX11_05090	COG2195	Cleaves the N-terminal amino acid of tripeptides
NGX11_05105	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NGX11_05110	COG0653	protein targeting
NGX11_05120	COG0521	Mo-molybdopterin cofactor biosynthetic process
NGX11_05130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NGX11_05135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NGX11_05145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NGX11_05175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NGX11_05180	COG4206	TonB-dependent receptor
NGX11_05200	COG0546	phosphoglycolate phosphatase activity
NGX11_05210	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NGX11_05235	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NGX11_05245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NGX11_05245	COG4191	Histidine kinase
NGX11_05255	COG0475	glutathione-regulated potassium exporter activity
NGX11_05255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NGX11_05290	COG0436	Aminotransferase
NGX11_05295	COG1451	nucleotide metabolic process
NGX11_05305	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NGX11_05310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NGX11_05310	COG0519	Catalyzes the synthesis of GMP from XMP
NGX11_05345	COG0596	Alpha beta hydrolase
NGX11_05360	COG5001	Diguanylate cyclase
NGX11_05360	COG5002	protein histidine kinase activity
NGX11_05365	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NGX11_05370	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NGX11_05375	COG0415	Belongs to the DNA photolyase family
NGX11_05380	COG1090	epimerase
NGX11_05390	COG3040	lipid binding
NGX11_05395	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NGX11_05405	COG3046	protein related to deoxyribodipyrimidine photolyase
NGX11_05420	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NGX11_05430	COG2200	EAL domain
NGX11_05435	COG3279	Response regulator of the LytR AlgR family
NGX11_05440	COG3275	phosphorelay sensor kinase activity
NGX11_05465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NGX11_05465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NGX11_05470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NGX11_05480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NGX11_05485	COG0735	belongs to the Fur family
NGX11_05495	COG0728	peptidoglycan biosynthetic process
NGX11_05500	COG1132	(ABC) transporter
NGX11_05505	COG0167	dihydroorotate dehydrogenase activity
NGX11_05510	COG0612	Peptidase, M16
NGX11_05515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NGX11_05520	COG1028	Short-chain dehydrogenase reductase Sdr
NGX11_05525	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NGX11_05530	COG0750	zinc metalloprotease
NGX11_05535	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NGX11_05545	COG0840	transmembrane signaling receptor activity
NGX11_05555	COG0642	Histidine kinase
NGX11_05560	COG0745	RESPONSE REGULATOR receiver
NGX11_05570	COG1132	(ABC) transporter
NGX11_05575	COG0217	transcriptional regulatory protein
NGX11_05595	COG1611	Belongs to the LOG family
NGX11_05600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NGX11_05620	COG0352	thiamine-phosphate diphosphorylase activity
NGX11_05620	COG0351	phosphomethylpyrimidine kinase
NGX11_05625	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NGX11_05660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NGX11_05665	COG1696	Membrane protein involved in D-alanine export
NGX11_05680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NGX11_05735	COG5002	protein histidine kinase activity
NGX11_05740	COG0745	RESPONSE REGULATOR receiver
NGX11_05765	COG1114	Component of the transport system for branched-chain amino acids
NGX11_05770	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NGX11_05775	COG0788	formyltetrahydrofolate deformylase activity
NGX11_05780	COG1496	oxidoreductase activity
NGX11_05785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NGX11_05790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NGX11_05800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NGX11_05815	COG0513	Belongs to the DEAD box helicase family
NGX11_05825	COG0754	glutathionylspermidine amidase activity
NGX11_05840	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NGX11_05845	COG0516	GMP reductase activity
NGX11_05845	COG0517	IMP dehydrogenase activity
NGX11_05850	COG0154	amidase activity
NGX11_05855	COG0203	ribosomal protein L17
NGX11_05860	COG0202	RNA polymerase activity
NGX11_05865	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NGX11_05870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NGX11_05875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NGX11_05880	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NGX11_05895	COG0473	3-isopropylmalate dehydrogenase activity
NGX11_05900	COG0066	3-isopropylmalate dehydratase activity
NGX11_05905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NGX11_05930	COG0357	Ribosomal RNA small subunit methyltransferase G
NGX11_05935	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NGX11_05940	COG0113	porphobilinogen synthase activity
NGX11_05980	COG0166	Belongs to the GPI family
NGX11_05995	COG2337	Toxic component of a toxin-antitoxin (TA) module
NGX11_06005	COG2161	toxin-antitoxin pair type II binding
NGX11_06025	COG1086	Polysaccharide biosynthesis protein
NGX11_06050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NGX11_06055	COG2161	toxin-antitoxin pair type II binding
NGX11_06065	COG0438	transferase activity, transferring glycosyl groups
NGX11_06070	COG0367	asparagine synthase
NGX11_06075	COG0438	transferase activity, transferring glycosyl groups
NGX11_06085	COG0367	asparagine synthase
NGX11_06095	COG0463	Glycosyl transferase, family 2
NGX11_06100	COG2244	polysaccharide biosynthetic process
NGX11_06115	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NGX11_06120	COG3265	gluconokinase activity
NGX11_06130	COG0673	inositol 2-dehydrogenase activity
NGX11_06165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NGX11_06190	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NGX11_06195	COG1215	transferase activity, transferring glycosyl groups
NGX11_06215	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NGX11_06220	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NGX11_06255	COG3177	Filamentation induced by cAMP protein fic
NGX11_06260	COG0582	viral genome integration into host DNA
NGX11_06340	COG3504	Conjugal transfer protein
NGX11_06355	COG3505	Type IV secretory pathway VirD4
NGX11_06425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NGX11_06525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NGX11_06535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NGX11_06545	COG2391	methyltransferase activity
NGX11_06550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NGX11_06555	COG0849	cell division
NGX11_06565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NGX11_06575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NGX11_06585	COG0446	pyridine nucleotide-disulphide oxidoreductase
NGX11_06590	COG0488	(ABC) transporter
NGX11_06595	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NGX11_06605	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NGX11_06610	COG0508	dehydrogenase complex catalyzes the overall conversion of
NGX11_06615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NGX11_06625	COG2217	Heavy metal translocating P-type atpase
NGX11_06630	COG0513	Belongs to the DEAD box helicase family
NGX11_06645	COG0840	transmembrane signaling receptor activity
NGX11_06650	COG0328	RNA-DNA hybrid ribonuclease activity
NGX11_06655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NGX11_06665	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NGX11_06675	COG0456	acetyltransferase
NGX11_06680	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NGX11_06695	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NGX11_06700	COG0131	Imidazoleglycerol-phosphate dehydratase
NGX11_06705	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NGX11_06715	COG0084	hydrolase, TatD family'
NGX11_06725	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NGX11_06730	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NGX11_06735	COG0359	binds to the 23S rRNA
NGX11_06745	COG0163	prenyltransferase activity
NGX11_06750	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NGX11_06755	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NGX11_06760	COG0124	histidyl-tRNA synthetase
NGX11_06765	COG1166	arginine decarboxylase activity
NGX11_06770	COG1045	serine acetyltransferase
NGX11_06775	COG0730	response to heat
NGX11_06805	COG1639	'signal transduction protein
NGX11_06810	COG0012	GTP binding
NGX11_06830	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NGX11_06840	COG1696	Membrane protein involved in D-alanine export
NGX11_06850	COG2855	membrane
NGX11_06855	COG0583	DNA-binding transcription factor activity
NGX11_06865	COG2267	carboxylic ester hydrolase activity
NGX11_06880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NGX11_06885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NGX11_06890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NGX11_06910	COG2986	histidine ammonia-lyase
NGX11_06915	COG1028	Short-chain dehydrogenase reductase Sdr
NGX11_06940	COG1131	(ABC) transporter
NGX11_06955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NGX11_06975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NGX11_06990	COG1032	radical SAM domain protein
NGX11_06995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NGX11_07005	COG1573	uracil-dna glycosylase
NGX11_07010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NGX11_07015	COG0024	Methionine aminopeptidase
NGX11_07020	COG0201	protein transport
NGX11_07025	COG0200	Binds to the 23S rRNA
NGX11_07030	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NGX11_07035	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NGX11_07040	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NGX11_07045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NGX11_07050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NGX11_07055	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NGX11_07060	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NGX11_07065	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NGX11_07070	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NGX11_07075	COG0255	Belongs to the universal ribosomal protein uL29 family
NGX11_07080	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NGX11_07085	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NGX11_07090	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NGX11_07095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NGX11_07100	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NGX11_07105	COG0089	rRNA binding
NGX11_07110	COG0088	Forms part of the polypeptide exit tunnel
NGX11_07115	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NGX11_07120	COG0051	transcription antitermination factor activity, RNA binding
NGX11_07140	COG0708	Exodeoxyribonuclease III
NGX11_07145	COG0301	tRNA thio-modification
NGX11_07145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NGX11_07165	COG0606	chelatase, subunit chli
NGX11_07175	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NGX11_07190	COG1525	nuclease
NGX11_07295	COG0840	transmembrane signaling receptor activity
NGX11_07300	COG0840	transmembrane signaling receptor activity
NGX11_07310	COG0242	peptide deformylase activity
NGX11_07315	COG0740	serine-type endopeptidase activity
NGX11_07320	COG0544	peptidyl-prolyl cis-trans isomerase activity
NGX11_07350	COG0582	viral genome integration into host DNA
NGX11_07355	COG4680	protein conserved in bacteria
NGX11_07365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NGX11_07375	COG1061	Type III restriction enzyme res subunit
NGX11_07445	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NGX11_07450	COG1355	regulation of microtubule-based process
NGX11_07470	COG3256	nitric oxide reductase
NGX11_07480	COG2010	Cytochrome c
NGX11_07485	COG2010	Cytochrome c
NGX11_07490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NGX11_07500	COG0535	radical SAM domain protein
NGX11_07510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NGX11_07510	COG1648	precorrin-2 dehydrogenase activity
NGX11_07520	COG1648	precorrin-2 dehydrogenase activity
NGX11_07520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NGX11_07525	COG1522	sequence-specific DNA binding
NGX11_07540	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NGX11_07555	COG1278	Cold shock
NGX11_07600	COG2217	Heavy metal translocating P-type atpase
NGX11_07605	COG2199	diguanylate cyclase activity
NGX11_07605	COG3287	FIST C domain
NGX11_07605	COG2200	EAL domain
NGX11_07610	COG0194	GDP metabolic process
NGX11_07620	COG1136	(ABC) transporter
NGX11_07625	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NGX11_07630	COG0052	Belongs to the universal ribosomal protein uS2 family
NGX11_07635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NGX11_07650	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NGX11_07655	COG0579	oxidoreductase
NGX11_07660	COG1546	Belongs to the CinA family
NGX11_07660	COG1058	Belongs to the CinA family
NGX11_07710	COG0745	RESPONSE REGULATOR receiver
NGX11_07720	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NGX11_07730	COG2176	DNA-directed DNA polymerase activity
NGX11_07760	COG2176	DNA-directed DNA polymerase activity
NGX11_07770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NGX11_07775	COG0280	phosphate acetyltransferase
NGX11_07785	COG0616	signal peptide processing
NGX11_07790	COG0402	S-adenosylhomocysteine deaminase activity
NGX11_07795	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NGX11_07800	COG0006	proline dipeptidase activity
NGX11_07805	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NGX11_07810	COG0482	sulfurtransferase activity
NGX11_07815	COG0482	sulfurtransferase activity
NGX11_07825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NGX11_07835	COG0481	GTPase activity
NGX11_07845	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NGX11_07850	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NGX11_07865	COG2095	MarC family integral membrane protein
NGX11_07870	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NGX11_07885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NGX11_07915	COG2885	chlorophyll binding
NGX11_07920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NGX11_07925	COG2264	protein methyltransferase activity
NGX11_07930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NGX11_07940	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NGX11_07950	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NGX11_07955	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NGX11_07960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NGX11_07975	COG0840	transmembrane signaling receptor activity
NGX11_08015	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NGX11_08025	COG0133	tryptophan synthase activity
NGX11_08030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NGX11_08035	COG1793	dna ligase
NGX11_08045	COG0626	cystathionine gamma-synthase activity
NGX11_08075	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NGX11_08115	COG0528	UMP kinase activity
NGX11_08120	COG1758	RNA polymerase activity
NGX11_08125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NGX11_08130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NGX11_08140	COG0860	N-Acetylmuramoyl-L-alanine amidase
NGX11_08155	COG0193	aminoacyl-tRNA hydrolase activity
NGX11_08160	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NGX11_08165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NGX11_08170	COG0681	Belongs to the peptidase S26 family
NGX11_08175	COG0698	ribose 5-phosphate isomerase
NGX11_08215	COG2199	diguanylate cyclase activity
NGX11_08215	COG2200	EAL domain
NGX11_08215	COG3287	FIST C domain
NGX11_08220	COG0259	pyridoxamine-phosphate oxidase activity
NGX11_08225	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NGX11_08235	COG0513	Belongs to the DEAD box helicase family
NGX11_08255	COG0326	Molecular chaperone. Has ATPase activity
NGX11_08270	COG0010	Belongs to the arginase family
NGX11_08280	COG4335	DNA alkylation repair
NGX11_08285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NGX11_08295	COG2264	protein methyltransferase activity
NGX11_08320	COG2995	paraquat-inducible protein a
NGX11_08325	COG3008	intermembrane lipid transfer
NGX11_08330	COG0753	catalase activity
NGX11_08345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NGX11_08350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NGX11_08360	COG0668	transmembrane transport
NGX11_08365	COG1227	inorganic diphosphatase activity
NGX11_08370	COG3012	SEC-C Motif Domain Protein
NGX11_08380	COG1027	Aspartate ammonia-lyase
NGX11_08385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NGX11_08390	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NGX11_08395	COG1047	Peptidyl-prolyl cis-trans
NGX11_08410	COG0823	Involved in the tonB-independent uptake of proteins
NGX11_08420	COG0848	biopolymer transport protein
NGX11_08425	COG0811	peptide transport
NGX11_08430	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NGX11_08435	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NGX11_08440	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NGX11_08445	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NGX11_08450	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NGX11_08455	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NGX11_08465	COG1475	DNA binding
NGX11_08470	COG1192	Involved in chromosome partitioning
NGX11_08485	COG0840	transmembrane signaling receptor activity
NGX11_08490	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NGX11_08495	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NGX11_08500	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NGX11_08505	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NGX11_08510	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NGX11_08515	COG0358	DNA primase activity
NGX11_08525	COG0571	ribonuclease III activity
NGX11_08530	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NGX11_08540	COG2326	polyphosphate kinase activity
NGX11_08555	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NGX11_08580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NGX11_08590	COG0739	heme binding
NGX11_08590	COG0741	lytic transglycosylase activity
NGX11_08590	COG1196	nuclear chromosome segregation
NGX11_08610	COG2183	response to ionizing radiation
NGX11_08615	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NGX11_08620	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NGX11_08625	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NGX11_08630	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NGX11_08630	COG0649	NAD binding
NGX11_08635	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NGX11_08645	COG0372	Belongs to the citrate synthase family
NGX11_08655	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NGX11_08660	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NGX11_08665	COG0839	Belongs to the complex I subunit 6 family
NGX11_08670	COG0713	ATP synthesis coupled electron transport
NGX11_08675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NGX11_08685	COG1007	ATP synthesis coupled electron transport
NGX11_08695	COG1053	succinate dehydrogenase
NGX11_08700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NGX11_08720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NGX11_08725	COG0416	fatty acid biosynthetic process
NGX11_08730	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NGX11_08740	COG0105	UTP biosynthetic process
NGX11_08750	COG0450	alkyl hydroperoxide reductase
NGX11_08755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NGX11_08760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NGX11_08765	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NGX11_08770	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NGX11_08780	COG0181	hydroxymethylbilane synthase activity
NGX11_08785	COG1335	isochorismatase
NGX11_08825	COG3278	Belongs to the heme-copper respiratory oxidase family
NGX11_08830	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NGX11_08835	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NGX11_08840	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NGX11_08855	COG1242	4 iron, 4 sulfur cluster binding
NGX11_08860	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NGX11_08865	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NGX11_08870	COG0492	ferredoxin-NADP+ reductase activity
NGX11_08875	COG3118	belongs to the thioredoxin family
NGX11_08880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NGX11_08935	COG0642	Histidine kinase
NGX11_08940	COG0745	RESPONSE REGULATOR receiver
NGX11_08950	COG0129	dihydroxy-acid dehydratase activity
NGX11_08970	COG0582	viral genome integration into host DNA
NGX11_09075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NGX11_09095	COG0585	pseudouridine synthase activity
NGX11_09110	COG0793	Belongs to the peptidase S41A family
NGX11_09115	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NGX11_09120	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NGX11_09125	COG0047	phosphoribosylformylglycinamidine synthase activity
NGX11_09135	COG0204	Acyl-transferase
NGX11_09140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NGX11_09145	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NGX11_09150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NGX11_09155	COG0018	arginyl-trna synthetase
NGX11_09165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NGX11_09170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NGX11_09175	COG0126	phosphoglycerate kinase activity
NGX11_09180	COG0149	triose-phosphate isomerase activity
NGX11_09185	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NGX11_09190	COG0019	diaminopimelate decarboxylase activity
NGX11_09195	COG0077	Prephenate dehydratase
NGX11_09195	COG1605	Chorismate mutase
NGX11_09200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NGX11_09205	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NGX11_09220	COG0424	maF-like protein
NGX11_09230	COG0791	NLP P60 protein
NGX11_09255	COG3118	belongs to the thioredoxin family
NGX11_09260	COG0189	ligase activity
NGX11_09275	COG2199	diguanylate cyclase activity
NGX11_09275	COG3287	FIST C domain
NGX11_09275	COG2200	EAL domain
NGX11_09280	COG0688	phosphatidylethanolamine metabolic process
NGX11_09290	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NGX11_09300	COG0288	reversible hydration of carbon dioxide
NGX11_09305	COG0156	8-amino-7-oxononanoate synthase activity
NGX11_09310	COG0792	nuclease activity
NGX11_09330	COG5002	protein histidine kinase activity
NGX11_09335	COG0745	RESPONSE REGULATOR receiver
NGX11_09385	COG1987	bacterial-type flagellum assembly
NGX11_09395	COG1706	bacterial-type flagellum-dependent cell motility
NGX11_09415	COG0004	ammonium transporteR
NGX11_09420	COG0666	response to abiotic stimulus
NGX11_09425	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NGX11_09450	COG1742	UPF0060 membrane protein
NGX11_09465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NGX11_09475	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NGX11_09490	COG0840	transmembrane signaling receptor activity
NGX11_09495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NGX11_09540	COG2022	thiamine diphosphate biosynthetic process
NGX11_09545	COG1324	tolerance protein
NGX11_09550	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NGX11_09550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NGX11_09560	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NGX11_09575	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NGX11_09580	COG0575	Belongs to the CDS family
NGX11_09605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NGX11_09610	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NGX11_09615	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NGX11_09620	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NGX11_09630	COG0446	pyridine nucleotide-disulphide oxidoreductase
NGX11_09635	COG0746	molybdenum cofactor guanylyltransferase activity
NGX11_09640	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NGX11_09645	COG1393	Belongs to the ArsC family
NGX11_09650	COG2828	Protein conserved in bacteria
NGX11_09655	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NGX11_09665	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NGX11_09675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NGX11_09680	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NGX11_09685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NGX11_09690	COG0560	Phosphoserine phosphatase
NGX11_09700	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NGX11_09710	COG0786	glutamate:sodium symporter activity
NGX11_09730	COG0736	holo-[acyl-carrier-protein] synthase activity
NGX11_09735	COG0601	transmembrane transport
NGX11_09740	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NGX11_09750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NGX11_09780	COG2824	Alkylphosphonate utilization operon protein PhnA
NGX11_09785	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NGX11_09795	COG0573	inorganic phosphate transmembrane transporter activity
NGX11_09800	COG0581	inorganic phosphate transmembrane transporter activity
NGX11_09805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NGX11_09810	COG0704	Plays a role in the regulation of phosphate uptake
NGX11_09820	COG0745	RESPONSE REGULATOR receiver
NGX11_09825	COG5002	protein histidine kinase activity
NGX11_09830	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NGX11_09835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NGX11_09840	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NGX11_09855	COG0546	phosphoglycolate phosphatase activity
NGX11_09875	COG1127	ABC transporter
NGX11_09880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NGX11_09885	COG1854	S-ribosylhomocysteine lyase activity
NGX11_09895	COG1686	Belongs to the peptidase S11 family
NGX11_09905	COG5002	protein histidine kinase activity
NGX11_09910	COG1410	methionine synthase
NGX11_09910	COG0646	methionine synthase
NGX11_09935	COG0140	phosphoribosyl-ATP diphosphatase activity
NGX11_09935	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NGX11_09950	COG0456	acetyltransferase
NGX11_09955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NGX11_09960	COG1917	Cupin 2, conserved barrel domain protein
NGX11_09965	COG0489	protein tyrosine kinase activity
NGX11_09970	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NGX11_09980	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NGX11_09980	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NGX11_09990	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NGX11_09995	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NGX11_10000	COG0268	Binds directly to 16S ribosomal RNA
NGX11_10005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NGX11_10010	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NGX11_10015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NGX11_10025	COG0540	Belongs to the ATCase OTCase family
NGX11_10030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NGX11_10035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NGX11_10040	COG0505	Belongs to the CarA family
NGX11_10050	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NGX11_10055	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NGX11_10060	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NGX11_10090	COG4895	conserved protein (DUF2196)
NGX11_10095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NGX11_10100	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NGX11_10105	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NGX11_10110	COG0237	dephospho-CoA kinase activity
NGX11_10120	COG0348	domain, Protein
NGX11_10125	COG0504	CTP synthase activity
NGX11_10130	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NGX11_10130	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NGX11_10145	COG0693	protein deglycase activity
NGX11_10150	COG0587	DNA-directed DNA polymerase activity
NGX11_10155	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NGX11_10170	COG0315	cyclic pyranopterin monophosphate synthase activity
NGX11_10175	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NGX11_10180	COG0428	transporter
NGX11_10235	COG0109	protoheme IX farnesyltransferase activity
NGX11_10245	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NGX11_10250	COG0254	rRNA binding
NGX11_10255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NGX11_10260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NGX11_10270	COG0436	Aminotransferase
NGX11_10275	COG0460	homoserine dehydrogenase
NGX11_10280	COG0564	pseudouridine synthase activity
NGX11_10285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NGX11_10290	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NGX11_10295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NGX11_10300	COG3047	cAMP biosynthetic process
NGX11_10300	COG2885	chlorophyll binding
NGX11_10310	COG4206	TonB-dependent receptor
NGX11_10325	COG0745	RESPONSE REGULATOR receiver
NGX11_10340	COG0604	alcohol dehydrogenase
NGX11_10345	COG1733	regulation of RNA biosynthetic process
NGX11_10350	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NGX11_10355	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NGX11_10365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NGX11_10365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NGX11_10370	COG0511	ligase activity, forming carbon-carbon bonds
NGX11_10375	COG0439	Biotin carboxylase
NGX11_10380	COG0513	Belongs to the DEAD box helicase family
NGX11_10385	COG1278	Cold shock
NGX11_10400	COG0306	phosphate transporter
NGX11_10410	COG0367	asparagine synthase
NGX11_10425	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NGX11_10430	COG1981	membrane
NGX11_10435	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NGX11_10435	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NGX11_10440	COG1187	pseudouridine synthase activity
NGX11_10445	COG0517	IMP dehydrogenase activity
NGX11_10445	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NGX11_10450	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NGX11_10455	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NGX11_10460	COG0107	imidazoleglycerol-phosphate synthase activity
NGX11_10475	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NGX11_10480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NGX11_10485	COG0724	RNA recognition motif
NGX11_10490	COG0745	RESPONSE REGULATOR receiver
NGX11_10495	COG0642	Histidine kinase
NGX11_10515	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NGX11_10520	COG2353	YceI-like domain
NGX11_10525	COG0133	tryptophan synthase activity
NGX11_10540	COG2337	Toxic component of a toxin-antitoxin (TA) module
NGX11_10560	COG1408	metallophosphoesterase
NGX11_10575	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NGX11_10580	COG4208	sulfate ABC transporter
NGX11_10585	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NGX11_10595	COG3287	FIST C domain
NGX11_10595	COG2200	EAL domain
NGX11_10595	COG2199	diguanylate cyclase activity
NGX11_10610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NGX11_10615	COG1959	2 iron, 2 sulfur cluster binding
NGX11_10620	COG1217	gtp-binding protein TYPA
NGX11_10625	COG2391	methyltransferase activity
NGX11_10630	COG0425	Belongs to the sulfur carrier protein TusA family
NGX11_10645	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NGX11_10675	COG0745	RESPONSE REGULATOR receiver
NGX11_10680	COG0642	Histidine kinase
NGX11_10685	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
NGX11_10690	COG2860	membrane
NGX11_10705	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NGX11_10715	COG0305	Participates in initiation and elongation during chromosome replication
NGX11_10745	COG0450	alkyl hydroperoxide reductase
NGX11_10750	COG3118	belongs to the thioredoxin family
NGX11_10900	COG4771	TonB-dependent receptor
NGX11_10920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NGX11_10955	COG2337	Toxic component of a toxin-antitoxin (TA) module
NGX11_10995	COG0039	L-malate dehydrogenase activity
NGX11_11015	COG1484	DNA-dependent DNA replication
NGX11_11080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NGX11_11110	COG4974	Belongs to the 'phage' integrase family
NGX11_11150	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NGX11_11185	COG0488	(ABC) transporter
NGX11_11220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NGX11_11245	COG3111	PFAM Bacterial OB fold (BOF) protein
NGX11_11250	COG0642	Histidine kinase
NGX11_11260	COG0745	RESPONSE REGULATOR receiver
NGX11_11265	COG0659	secondary active sulfate transmembrane transporter activity
NGX11_11315	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NGX11_11435	COG0488	(ABC) transporter
NGX11_11465	COG1121	(ABC) transporter
NGX11_11475	COG0419	ATPase involved in DNA repair
NGX11_11480	COG0420	3'-5' exonuclease activity
NGX11_11485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NGX11_11490	COG1192	Involved in chromosome partitioning
NGX11_11495	COG1475	DNA binding