locus-tag	class	description
Alide_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Alide_0005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_0006	COG1024	Enoyl-CoA hydratase
Alide_0007	COG0583	DNA-binding transcription factor activity
Alide_0008	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_0011	COG1960	acyl-CoA dehydrogenase activity
Alide_0012	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Alide_0013	COG1254	Belongs to the acylphosphatase family
Alide_0016	COG1199	ATP-dependent helicase activity
Alide_0018	COG0791	NLP P60 protein
Alide_0019	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Alide_0023	COG1960	acyl-CoA dehydrogenase activity
Alide_0024	COG1960	acyl-CoA dehydrogenase activity
Alide_0027	COG1024	Enoyl-CoA hydratase
Alide_0031	COG2974	May be involved in recombination
Alide_0032	COG0700	Nucleoside recognition
Alide_0035	COG0789	Transcriptional regulator
Alide_0042	COG0745	RESPONSE REGULATOR receiver
Alide_0043	COG0642	Histidine kinase
Alide_0044	COG1902	pentaerythritol trinitrate reductase activity
Alide_0048	COG0445	tRNA wobble uridine modification
Alide_0050	COG0357	Ribosomal RNA small subunit methyltransferase G
Alide_0052	COG1192	Involved in chromosome partitioning
Alide_0054	COG1475	DNA binding
Alide_0059	COG0668	transmembrane transport
Alide_0061	COG0277	FAD linked oxidase domain protein
Alide_0064	COG2369	cell adhesion
Alide_0077	COG2096	Adenosyltransferase
Alide_0078	COG2050	protein possibly involved in aromatic compounds catabolism
Alide_0083	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_0086	COG2233	PERMEase
Alide_0089	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Alide_0090	COG0583	DNA-binding transcription factor activity
Alide_0092	COG1960	acyl-CoA dehydrogenase activity
Alide_0093	COG1960	acyl-CoA dehydrogenase activity
Alide_0095	COG1183	phosphatidylcholine synthase activity
Alide_0096	COG4774	siderophore transport
Alide_0099	COG0850	regulation of cytokinetic process
Alide_0101	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Alide_0102	COG0583	DNA-binding transcription factor activity
Alide_0103	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_0104	COG4948	Mandelate Racemase Muconate Lactonizing
Alide_0105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Alide_0106	COG2267	carboxylic ester hydrolase activity
Alide_0112	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Alide_0114	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Alide_0115	COG1960	acyl-CoA dehydrogenase activity
Alide_0118	COG0583	DNA-binding transcription factor activity
Alide_0121	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_0122	COG0514	ATP-dependent DNA helicase (RecQ)
Alide_0128	COG3256	nitric oxide reductase
Alide_0129	COG3604	Transcriptional regulator
Alide_0131	COG1760	l-serine dehydratase
Alide_0133	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_0143	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_0149	COG0183	Belongs to the thiolase family
Alide_0150	COG1960	acyl-CoA dehydrogenase activity
Alide_0153	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_0162	COG1960	acyl-CoA dehydrogenase activity
Alide_0163	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
Alide_0164	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_0165	COG2030	dehydratase
Alide_0166	COG1024	Enoyl-CoA hydratase
Alide_0167	COG0427	acetyl-CoA hydrolase
Alide_0168	COG0183	Belongs to the thiolase family
Alide_0173	COG0583	DNA-binding transcription factor activity
Alide_0175	COG1473	amidohydrolase
Alide_0177	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_0180	COG1473	amidohydrolase
Alide_0183	COG1960	acyl-CoA dehydrogenase activity
Alide_0188	COG1960	acyl-CoA dehydrogenase activity
Alide_0189	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Alide_0190	COG1960	acyl-CoA dehydrogenase activity
Alide_0191	COG1024	Enoyl-CoA hydratase
Alide_0197	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_0198	COG0583	DNA-binding transcription factor activity
Alide_0201	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Alide_0204	COG1410	methionine synthase
Alide_0204	COG0646	methionine synthase
Alide_0209	COG2948	multi-organism process
Alide_0212	COG3846	protein secretion by the type IV secretion system
Alide_0214	COG3451	type IV secretory pathway VirB4
Alide_0216	COG3838	Conjugal transfer protein Trbc
Alide_0217	COG4962	Type ii secretion system protein e
Alide_0221	COG0583	DNA-binding transcription factor activity
Alide_0228	COG0642	Histidine kinase
Alide_0232	COG0789	Transcriptional regulator
Alide_0238	COG1192	Involved in chromosome partitioning
Alide_0243	COG1396	sequence-specific DNA binding
Alide_0244	COG5489	Protein of unknown function (DUF736)
Alide_0254	COG3657	addiction module killer protein
Alide_0256	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Alide_0260	COG0683	leucine binding
Alide_0268	COG0347	Belongs to the P(II) protein family
Alide_0269	COG0004	ammonium transporteR
Alide_0271	COG2084	Dehydrogenase
Alide_0277	COG2267	carboxylic ester hydrolase activity
Alide_0279	COG3180	Ammonia monooxygenase
Alide_0280	COG2079	MmgE PrpD family protein
Alide_0283	COG1042	CoA-binding domain protein
Alide_0283	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Alide_0283	COG0045	succinate-CoA ligase (ADP-forming) activity
Alide_0284	COG0277	FAD linked oxidase domain protein
Alide_0286	COG0247	lactate metabolic process
Alide_0289	COG0477	Major facilitator Superfamily
Alide_0290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Alide_0291	COG1858	cytochrome C peroxidase
Alide_0292	COG0625	glutathione transferase activity
Alide_0295	COG0154	amidase activity
Alide_0301	COG1216	Glycosyl transferase, family 2
Alide_0305	COG0477	Major facilitator Superfamily
Alide_0306	COG2258	MOSC domain
Alide_0310	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_0313	COG2205	protein histidine kinase activity
Alide_0314	COG0745	RESPONSE REGULATOR receiver
Alide_0318	COG0501	Belongs to the peptidase M48B family
Alide_0338	COG4569	acetaldehyde dehydrogenase (acetylating) activity
Alide_0343	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Alide_0344	COG1414	Transcriptional regulator
Alide_0348	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Alide_0349	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Alide_0353	COG3386	PFAM SMP-30 Gluconolaconase
Alide_0355	COG2084	Dehydrogenase
Alide_0356	COG1012	belongs to the aldehyde dehydrogenase family
Alide_0357	COG1414	Transcriptional regulator
Alide_0364	COG0410	ABC transporter
Alide_0367	COG1960	acyl-CoA dehydrogenase activity
Alide_0368	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_0370	COG0708	Exodeoxyribonuclease III
Alide_0371	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Alide_0373	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Alide_0374	COG0154	amidase activity
Alide_0375	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Alide_0376	COG1077	Cell shape determining protein MreB Mrl
Alide_0378	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Alide_0379	COG0768	penicillin binding
Alide_0381	COG0730	response to heat
Alide_0383	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Alide_0384	COG1127	ABC transporter
Alide_0385	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Alide_0385	COG3008	intermembrane lipid transfer
Alide_0388	COG0583	DNA-binding transcription factor activity
Alide_0389	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Alide_0391	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Alide_0392	COG2095	MarC family integral membrane protein
Alide_0393	COG0412	Dienelactone hydrolase
Alide_0398	COG0598	Magnesium transport protein CorA
Alide_0404	COG2945	thiolester hydrolase activity
Alide_0405	COG1686	Belongs to the peptidase S11 family
Alide_0406	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Alide_0407	COG0049	tRNA binding
Alide_0408	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Alide_0409	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Alide_0410	COG0051	transcription antitermination factor activity, RNA binding
Alide_0411	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Alide_0412	COG0088	Forms part of the polypeptide exit tunnel
Alide_0413	COG0089	rRNA binding
Alide_0414	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Alide_0415	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Alide_0416	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Alide_0417	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Alide_0418	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Alide_0419	COG0255	Belongs to the universal ribosomal protein uL29 family
Alide_0420	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Alide_0421	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Alide_0421	COG0678	peroxiredoxin activity
Alide_0424	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Alide_0427	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Alide_0428	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Alide_0429	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Alide_0430	COG0321	lipoyl(octanoyl) transferase activity
Alide_0431	COG2921	Belongs to the UPF0250 family
Alide_0433	COG0356	it plays a direct role in the translocation of protons across the membrane
Alide_0435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Alide_0436	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Alide_0437	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Alide_0438	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Alide_0439	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Alide_0440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Alide_0450	COG3245	cytochrome
Alide_0451	COG1538	Outer membrane efflux protein
Alide_0452	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Alide_0453	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Alide_0455	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Alide_0456	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Alide_0458	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Alide_0459	COG0081	regulation of translation
Alide_0460	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Alide_0461	COG0222	ribosome binding
Alide_0462	COG0085	RNA polymerase activity
Alide_0463	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Alide_0465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Alide_0465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Alide_0467	COG5000	phosphorelay sensor kinase activity
Alide_0468	COG2204	response regulator
Alide_0471	COG1396	sequence-specific DNA binding
Alide_0472	COG2856	Zn peptidase
Alide_0483	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Alide_0484	COG0463	Glycosyl transferase, family 2
Alide_0487	COG0792	nuclease activity
Alide_0488	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Alide_0490	COG2084	Dehydrogenase
Alide_0492	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Alide_0494	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Alide_0497	COG2733	membrane
Alide_0498	COG0277	FAD linked oxidase domain protein
Alide_0499	COG0583	DNA-binding transcription factor activity
Alide_0501	COG5001	Diguanylate cyclase
Alide_0504	COG4585	Histidine kinase
Alide_0505	COG2197	response regulator
Alide_0507	COG2223	nitrite transmembrane transporter activity
Alide_0508	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Alide_0509	COG1140	nitrate reductase beta subunit
Alide_0510	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
Alide_0511	COG2181	nitrate reductase activity
Alide_0513	COG0288	reversible hydration of carbon dioxide
Alide_0516	COG3945	hemerythrin HHE cation binding domain
Alide_0521	COG0243	molybdopterin cofactor binding
Alide_0523	COG2301	Belongs to the HpcH HpaI aldolase family
Alide_0524	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_0525	COG2030	dehydratase
Alide_0527	COG2030	dehydratase
Alide_0531	COG1473	amidohydrolase
Alide_0534	COG2818	Glycosylase
Alide_0536	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Alide_0544	COG0559	Belongs to the binding-protein-dependent transport system permease family
Alide_0546	COG1022	Amp-dependent synthetase and ligase
Alide_0547	COG3267	Type II secretory pathway component ExeA
Alide_0547	COG3409	Peptidoglycan-binding domain 1 protein
Alide_0549	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Alide_0550	COG1187	pseudouridine synthase activity
Alide_0551	COG0326	Molecular chaperone. Has ATPase activity
Alide_0553	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_0554	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Alide_0557	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_0560	COG1250	3-hydroxyacyl-CoA dehydrogenase
Alide_0565	COG1131	(ABC) transporter
Alide_0566	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Alide_0567	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Alide_0568	COG5001	Diguanylate cyclase
Alide_0568	COG3300	MHYT domain
Alide_0569	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Alide_0570	COG1490	D-aminoacyl-tRNA deacylase activity
Alide_0571	COG0730	response to heat
Alide_0574	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_0575	COG0604	alcohol dehydrogenase
Alide_0576	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_0577	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Alide_0578	COG1702	phosphate starvation-inducible protein PhoH
Alide_0579	COG0632	four-way junction helicase activity
Alide_0582	COG0443	Heat shock 70 kDa protein
Alide_0584	COG2255	four-way junction helicase activity
Alide_0585	COG1285	pathogenesis
Alide_0591	COG0037	tRNA processing
Alide_0598	COG1940	carbohydrate kinase activity
Alide_0599	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Alide_0601	COG1877	trehalose-phosphatase activity
Alide_0603	COG0617	tRNA 3'-terminal CCA addition
Alide_0607	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_0610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Alide_0611	COG1196	nuclear chromosome segregation
Alide_0611	COG0739	heme binding
Alide_0611	COG0741	lytic transglycosylase activity
Alide_0614	COG3128	pkhd-type hydroxylase
Alide_0616	COG4774	siderophore transport
Alide_0618	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_0621	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Alide_0622	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Alide_0625	COG1522	sequence-specific DNA binding
Alide_0627	COG3186	Phenylalanine-4-hydroxylase
Alide_0629	COG0022	dehydrogenase e1 component
Alide_0632	COG0752	glycyl-tRNA synthetase alpha subunit
Alide_0633	COG0751	glycine-tRNA ligase activity
Alide_0634	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Alide_0635	COG0204	Acyl-transferase
Alide_0638	COG1652	LysM domain
Alide_0639	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Alide_0648	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Alide_0654	COG3156	type II secretion system protein K
Alide_0658	COG1450	Type ii and iii secretion system protein
Alide_0669	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Alide_0670	COG0739	heme binding
Alide_0670	COG0741	lytic transglycosylase activity
Alide_0670	COG1196	nuclear chromosome segregation
Alide_0672	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Alide_0675	COG1960	acyl-CoA dehydrogenase activity
Alide_0677	COG1024	Enoyl-CoA hydratase
Alide_0677	COG1250	3-hydroxyacyl-CoA dehydrogenase
Alide_0678	COG0183	Belongs to the thiolase family
Alide_0680	COG1024	Enoyl-CoA hydratase
Alide_0682	COG1607	acyl-coa hydrolase
Alide_0683	COG5265	(ABC) transporter
Alide_0684	COG1021	2,3-dihydroxybenzoate-AMP ligase
Alide_0688	COG0583	DNA-binding transcription factor activity
Alide_0690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Alide_0692	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Alide_0693	COG0583	DNA-binding transcription factor activity
Alide_0694	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Alide_0695	COG0765	amino acid transport
Alide_0696	COG0765	amino acid transport
Alide_0697	COG1126	abc transporter atp-binding protein
Alide_0698	COG2423	ornithine cyclodeaminase activity
Alide_0700	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Alide_0702	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Alide_0704	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Alide_0705	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Alide_0706	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Alide_0708	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Alide_0709	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Alide_0710	COG0316	Belongs to the HesB IscA family
Alide_0712	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Alide_0713	COG0739	heme binding
Alide_0715	COG0583	DNA-binding transcription factor activity
Alide_0716	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Alide_0717	COG2205	protein histidine kinase activity
Alide_0720	COG1522	sequence-specific DNA binding
Alide_0721	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Alide_0729	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Alide_0730	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
Alide_0731	COG0745	RESPONSE REGULATOR receiver
Alide_0732	COG5002	protein histidine kinase activity
Alide_0738	COG0489	protein tyrosine kinase activity
Alide_0740	COG3267	Type II secretory pathway component ExeA
Alide_0740	COG3409	Peptidoglycan-binding domain 1 protein
Alide_0745	COG0367	asparagine synthase
Alide_0746	COG0438	transferase activity, transferring glycosyl groups
Alide_0747	COG0297	glycogen (starch) synthase activity
Alide_0749	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Alide_0750	COG0438	transferase activity, transferring glycosyl groups
Alide_0756	COG1216	Glycosyl transferase, family 2
Alide_0756	COG0463	Glycosyl transferase, family 2
Alide_0758	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Alide_0767	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_0769	COG5002	protein histidine kinase activity
Alide_0769	COG3850	Histidine kinase
Alide_0770	COG2204	response regulator
Alide_0773	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Alide_0775	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_0780	COG3045	CreA protein
Alide_0783	COG1132	(ABC) transporter
Alide_0789	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Alide_0803	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Alide_0804	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Alide_0805	COG1765	OsmC-like protein
Alide_0806	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
Alide_0810	COG1473	amidohydrolase
Alide_0811	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Alide_0812	COG0444	Belongs to the ABC transporter superfamily
Alide_0813	COG4608	Belongs to the ABC transporter superfamily
Alide_0814	COG1881	PFAM PEBP family protein
Alide_0816	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Alide_0817	COG0166	Belongs to the GPI family
Alide_0818	COG0459	protein refolding
Alide_0819	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Alide_0820	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Alide_0821	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Alide_0823	COG1560	Kdo2-lipid A biosynthetic process
Alide_0824	COG0583	DNA-binding transcription factor activity
Alide_0826	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_0827	COG0473	3-isopropylmalate dehydrogenase activity
Alide_0829	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Alide_0831	COG1333	cytochrome c biogenesis protein
Alide_0833	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Alide_0834	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Alide_0838	COG1965	Belongs to the frataxin family
Alide_0847	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Alide_0854	COG0069	glutamate synthase activity
Alide_0854	COG0070	glutamate synthase
Alide_0854	COG0067	glutamate synthase
Alide_0857	COG0765	amino acid transport
Alide_0860	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Alide_0861	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Alide_0862	COG1127	ABC transporter
Alide_0863	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Alide_0864	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Alide_0868	COG3706	GGDEF domain
Alide_0868	COG0745	RESPONSE REGULATOR receiver
Alide_0869	COG1131	(ABC) transporter
Alide_0870	COG0842	Transport permease protein
Alide_0871	COG5007	Belongs to the BolA IbaG family
Alide_0872	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Alide_0873	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Alide_0877	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Alide_0878	COG0131	Imidazoleglycerol-phosphate dehydratase
Alide_0880	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Alide_0883	COG0438	transferase activity, transferring glycosyl groups
Alide_0889	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Alide_0890	COG0107	imidazoleglycerol-phosphate synthase activity
Alide_0891	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Alide_0892	COG0140	phosphoribosyl-ATP diphosphatase activity
Alide_0895	COG0537	adenosine 5'-monophosphoramidase activity
Alide_0896	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Alide_0897	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Alide_0898	COG0805	protein transport
Alide_0899	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Alide_0900	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Alide_0901	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Alide_0902	COG1970	mechanosensitive ion channel activity
Alide_0903	COG0723	plastoquinol--plastocyanin reductase activity
Alide_0904	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Alide_0905	COG2857	Cytochrome c1
Alide_0906	COG0625	glutathione transferase activity
Alide_0907	COG2969	positive regulation of protein catabolic process
Alide_0909	COG0653	protein targeting
Alide_0912	COG0494	nUDIX hydrolase
Alide_0913	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Alide_0914	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
Alide_0915	COG0237	dephospho-CoA kinase activity
Alide_0925	COG0142	geranyltranstransferase activity
Alide_0926	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Alide_0927	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Alide_0928	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Alide_0929	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Alide_0930	COG0494	nUDIX hydrolase
Alide_0931	COG0442	prolyl-tRNA aminoacylation
Alide_0933	COG1253	flavin adenine dinucleotide binding
Alide_0934	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Alide_0935	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Alide_0936	COG2890	protein-(glutamine-N5) methyltransferase activity
Alide_0937	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Alide_0938	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Alide_0943	COG3264	Mechanosensitive ion channel
Alide_0943	COG1511	domain protein
Alide_0944	COG0584	glycerophosphoryl diester phosphodiesterase
Alide_0945	COG3842	ATPase activity
Alide_0946	COG0395	ABC-type sugar transport system, permease component
Alide_0947	COG1175	transmembrane transport
Alide_0948	COG1653	transport
Alide_0949	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Alide_0953	COG2226	methyltransferase
Alide_0956	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Alide_0960	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Alide_0963	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Alide_0964	COG0302	gtp cyclohydrolase
Alide_0967	COG4191	Histidine kinase
Alide_0968	COG4566	intracellular signal transduction
Alide_0969	COG3258	Cytochrome c
Alide_0972	COG1280	lysine exporter protein (LysE YggA)
Alide_0973	COG0154	amidase activity
Alide_0975	COG4608	Belongs to the ABC transporter superfamily
Alide_0976	COG0444	Belongs to the ABC transporter superfamily
Alide_0977	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Alide_0979	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Alide_0980	COG0193	aminoacyl-tRNA hydrolase activity
Alide_0981	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Alide_0982	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Alide_0983	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Alide_0986	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Alide_0988	COG1194	a g-specific adenine glycosylase
Alide_0989	COG1660	Displays ATPase and GTPase activities
Alide_0990	COG0497	DNA recombination
Alide_0991	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Alide_0992	COG1420	regulation of RNA biosynthetic process
Alide_0993	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Alide_0994	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Alide_0997	COG0765	amino acid transport
Alide_0998	COG0765	amino acid transport
Alide_1000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Alide_1001	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Alide_1004	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Alide_1005	COG1984	allophanate hydrolase subunit 2
Alide_1006	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Alide_1008	COG0439	Biotin carboxylase
Alide_1011	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Alide_1012	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Alide_1016	COG1561	YicC-like family, N-terminal region
Alide_1030	COG1222	aaa ATPase
Alide_1036	COG0194	GDP metabolic process
Alide_1037	COG1758	RNA polymerase activity
Alide_1038	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Alide_1041	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Alide_1042	COG1185	polyribonucleotide nucleotidyltransferase activity
Alide_1044	COG0149	triose-phosphate isomerase activity
Alide_1046	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Alide_1047	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Alide_1048	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Alide_1049	COG0649	NAD binding
Alide_1052	COG1034	ATP synthesis coupled electron transport
Alide_1053	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Alide_1054	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Alide_1056	COG0713	ATP synthesis coupled electron transport
Alide_1059	COG1007	ATP synthesis coupled electron transport
Alide_1063	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Alide_1064	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Alide_1066	COG0586	Pfam SNARE associated Golgi protein
Alide_1067	COG0402	S-adenosylhomocysteine deaminase activity
Alide_1068	COG2252	PERMEase
Alide_1070	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Alide_1071	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Alide_1073	COG0860	N-Acetylmuramoyl-L-alanine amidase
Alide_1074	COG0802	atpase or kinase
Alide_1078	COG4974	Belongs to the 'phage' integrase family
Alide_1079	COG0840	transmembrane signaling receptor activity
Alide_1081	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Alide_1082	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Alide_1083	COG2833	Protein of unknown function (DUF455)
Alide_1085	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Alide_1086	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Alide_1087	COG4215	(ABC) transporter
Alide_1090	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Alide_1091	COG0148	phosphopyruvate hydratase activity
Alide_1093	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Alide_1094	COG0504	CTP synthase activity
Alide_1095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Alide_1097	COG0756	dUTP diphosphatase activity
Alide_1098	COG1047	Peptidyl-prolyl cis-trans
Alide_1099	COG2850	peptidyl-arginine hydroxylation
Alide_1101	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
Alide_1102	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Alide_1114	COG1722	exodeoxyribonuclease VII activity
Alide_1116	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Alide_1117	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Alide_1118	COG1201	RNA secondary structure unwinding
Alide_1119	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Alide_1123	COG1045	serine acetyltransferase
Alide_1125	COG1063	alcohol dehydrogenase
Alide_1126	COG0521	Mo-molybdopterin cofactor biosynthetic process
Alide_1127	COG3028	Belongs to the UPF0307 family
Alide_1128	COG0312	modulator of DNA gyrase
Alide_1135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Alide_1142	COG0114	fumarate hydratase activity
Alide_1143	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Alide_1144	COG2113	Glycine betaine
Alide_1145	COG4176	ABC-type proline glycine betaine transport system permease component
Alide_1146	COG4175	Glycine betaine
Alide_1148	COG2304	oxidoreductase activity
Alide_1150	COG0714	Associated with various cellular activities
Alide_1151	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Alide_1153	COG0640	Transcriptional regulator
Alide_1155	COG0084	hydrolase, TatD family'
Alide_1157	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Alide_1158	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Alide_1161	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_1164	COG0697	spore germination
Alide_1167	COG0583	DNA-binding transcription factor activity
Alide_1170	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Alide_1171	COG3842	ATPase activity
Alide_1173	COG4149	molybdate abc transporter
Alide_1174	COG1840	ABC-type Fe3 transport system, periplasmic component
Alide_1175	COG1609	Transcriptional regulator
Alide_1176	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Alide_1177	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Alide_1178	COG0196	riboflavin kinase activity
Alide_1180	COG1960	acyl-CoA dehydrogenase activity
Alide_1181	COG1960	acyl-CoA dehydrogenase activity
Alide_1182	COG3132	Protein of unknown function, DUF480
Alide_1183	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Alide_1184	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Alide_1184	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Alide_1185	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Alide_1186	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Alide_1187	COG0492	ferredoxin-NADP+ reductase activity
Alide_1188	COG1674	ftsk spoiiie
Alide_1189	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Alide_1190	COG1575	Belongs to the MenA family. Type 1 subfamily
Alide_1191	COG1573	uracil-dna glycosylase
Alide_1192	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Alide_1195	COG0411	ABC transporter
Alide_1199	COG1392	Phosphate transport regulator
Alide_1200	COG0306	phosphate transporter
Alide_1203	COG0228	four-way junction DNA binding
Alide_1204	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Alide_1205	COG0336	Belongs to the RNA methyltransferase TrmD family
Alide_1206	COG0335	large ribosomal subunit rRNA binding
Alide_1207	COG0494	nUDIX hydrolase
Alide_1208	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Alide_1209	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Alide_1210	COG0659	secondary active sulfate transmembrane transporter activity
Alide_1211	COG1162	GTPase activity
Alide_1212	COG2154	pterin-4-alpha-carbinolamine dehydratase
Alide_1213	COG0501	Belongs to the peptidase M48B family
Alide_1214	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Alide_1216	COG0513	Belongs to the DEAD box helicase family
Alide_1217	COG5002	protein histidine kinase activity
Alide_1217	COG5001	Diguanylate cyclase
Alide_1217	COG3447	MASE1 domain protein
Alide_1218	COG2814	Major facilitator Superfamily
Alide_1225	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Alide_1227	COG4771	TonB-dependent receptor
Alide_1251	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Alide_1285	COG4695	Portal protein
Alide_1286	COG0516	GMP reductase activity
Alide_1287	COG0210	DNA helicase
Alide_1289	COG5001	Diguanylate cyclase
Alide_1289	COG4251	negative regulation of phosphorylation
Alide_1289	COG3706	GGDEF domain
Alide_1289	COG2203	Gaf domain
Alide_1291	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Alide_1296	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_1299	COG0583	DNA-binding transcription factor activity
Alide_1301	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_1302	COG1024	Enoyl-CoA hydratase
Alide_1303	COG0412	Dienelactone hydrolase
Alide_1306	COG0560	Phosphoserine phosphatase
Alide_1309	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Alide_1310	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Alide_1310	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Alide_1311	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Alide_1312	COG2205	protein histidine kinase activity
Alide_1313	COG0745	RESPONSE REGULATOR receiver
Alide_1315	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_1317	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Alide_1319	COG0724	RNA recognition motif
Alide_1320	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
Alide_1321	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Alide_1325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Alide_1326	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_1328	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Alide_1333	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_1334	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Alide_1337	COG1122	ATPase activity
Alide_1344	COG0411	ABC transporter
Alide_1348	COG0559	Belongs to the binding-protein-dependent transport system permease family
Alide_1353	COG0071	Belongs to the small heat shock protein (HSP20) family
Alide_1354	COG1136	(ABC) transporter
Alide_1355	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Alide_1357	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Alide_1358	COG0537	adenosine 5'-monophosphoramidase activity
Alide_1361	COG3447	MASE1 domain protein
Alide_1361	COG5001	Diguanylate cyclase
Alide_1361	COG5002	protein histidine kinase activity
Alide_1362	COG1129	ABC transporter
Alide_1367	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Alide_1368	COG1126	abc transporter atp-binding protein
Alide_1370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Alide_1371	COG1414	Transcriptional regulator
Alide_1373	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Alide_1375	COG4166	transmembrane transport
Alide_1376	COG4608	Belongs to the ABC transporter superfamily
Alide_1377	COG0444	Belongs to the ABC transporter superfamily
Alide_1378	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Alide_1379	COG0601	transmembrane transport
Alide_1381	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Alide_1389	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Alide_1390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Alide_1392	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Alide_1394	COG0268	Binds directly to 16S ribosomal RNA
Alide_1395	COG0728	peptidoglycan biosynthetic process
Alide_1397	COG0589	response to stress
Alide_1399	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Alide_1400	COG0405	Gamma-glutamyltransferase
Alide_1401	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Alide_1403	COG0617	tRNA 3'-terminal CCA addition
Alide_1404	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Alide_1405	COG0463	Glycosyl transferase, family 2
Alide_1406	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Alide_1412	COG0583	DNA-binding transcription factor activity
Alide_1413	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Alide_1419	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_1420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_1421	COG1960	acyl-CoA dehydrogenase activity
Alide_1422	COG0583	DNA-binding transcription factor activity
Alide_1445	COG0582	viral genome integration into host DNA
Alide_1447	COG0513	Belongs to the DEAD box helicase family
Alide_1448	COG0488	(ABC) transporter
Alide_1450	COG3191	aminopeptidase activity
Alide_1456	COG0789	Transcriptional regulator
Alide_1461	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Alide_1461	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Alide_1464	COG0052	Belongs to the universal ribosomal protein uS2 family
Alide_1465	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Alide_1466	COG0528	UMP kinase activity
Alide_1467	COG0233	cytoplasmic translational termination
Alide_1468	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Alide_1469	COG0575	Belongs to the CDS family
Alide_1470	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Alide_1471	COG0750	zinc metalloprotease
Alide_1474	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Alide_1475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Alide_1476	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Alide_1477	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Alide_1478	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Alide_1479	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Alide_1480	COG4974	Belongs to the 'phage' integrase family
Alide_1484	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Alide_1485	COG0308	aminopeptidase N
Alide_1489	COG1840	ABC-type Fe3 transport system, periplasmic component
Alide_1491	COG3842	ATPase activity
Alide_1492	COG0667	Aldo Keto reductase
Alide_1493	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Alide_1494	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Alide_1496	COG3577	Aspartyl protease
Alide_1497	COG1666	GTP binding
Alide_1498	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Alide_1500	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Alide_1501	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Alide_1502	COG0145	ligase activity
Alide_1503	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
Alide_1504	COG4647	ligase activity
Alide_1505	COG3284	Transcriptional regulator
Alide_1506	COG0137	argininosuccinate synthase activity
Alide_1507	COG3123	guanosine phosphorylase activity
Alide_1509	COG1393	Belongs to the ArsC family
Alide_1510	COG0285	dihydrofolate synthase activity
Alide_1512	COG1286	toxin biosynthetic process
Alide_1515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Alide_1520	COG4372	Transposase
Alide_1529	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Alide_1532	COG1840	ABC-type Fe3 transport system, periplasmic component
Alide_1535	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Alide_1537	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Alide_1541	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Alide_1544	COG2212	antiporter activity
Alide_1546	COG0651	ATP synthesis coupled electron transport
Alide_1547	COG1006	Multisubunit Na H antiporter MnhC subunit
Alide_1548	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Alide_1548	COG2111	Na H antiporter
Alide_1552	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Alide_1554	COG2917	probably involved in intracellular septation
Alide_1555	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Alide_1559	COG0559	Belongs to the binding-protein-dependent transport system permease family
Alide_1561	COG0411	ABC transporter
Alide_1563	COG1250	3-hydroxyacyl-CoA dehydrogenase
Alide_1563	COG1024	Enoyl-CoA hydratase
Alide_1564	COG0183	Belongs to the thiolase family
Alide_1566	COG0765	amino acid transport
Alide_1567	COG0765	amino acid transport
Alide_1568	COG1960	acyl-CoA dehydrogenase activity
Alide_1580	COG0582	viral genome integration into host DNA
Alide_1584	COG1309	transcriptional regulator
Alide_1585	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Alide_1591	COG0259	pyridoxamine-phosphate oxidase activity
Alide_1596	COG2183	response to ionizing radiation
Alide_1601	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_1602	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_1604	COG1609	Transcriptional regulator
Alide_1609	COG3618	amidohydrolase
Alide_1616	COG4566	intracellular signal transduction
Alide_1618	COG2807	transmembrane transport
Alide_1619	COG0590	tRNA wobble adenosine to inosine editing
Alide_1621	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Alide_1622	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Alide_1623	COG0470	DNA polymerase III
Alide_1625	COG0084	hydrolase, TatD family'
Alide_1629	COG1802	Transcriptional regulator
Alide_1631	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Alide_1632	COG4336	lyase activity
Alide_1633	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Alide_1634	COG4770	biotin carboxylase activity
Alide_1635	COG1132	(ABC) transporter
Alide_1636	COG0823	Involved in the tonB-independent uptake of proteins
Alide_1638	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
Alide_1639	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Alide_1640	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Alide_1669	COG0305	Participates in initiation and elongation during chromosome replication
Alide_1672	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
Alide_1690	COG0758	DNA mediated transformation
Alide_1715	COG3039	Transposase
Alide_1724	COG0582	viral genome integration into host DNA
Alide_1727	COG1388	LysM domain
Alide_1727	COG0741	lytic transglycosylase activity
Alide_1728	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Alide_1729	COG2226	methyltransferase
Alide_1730	COG0328	RNA-DNA hybrid ribonuclease activity
Alide_1732	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Alide_1733	COG0473	3-isopropylmalate dehydrogenase activity
Alide_1733	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Alide_1734	COG0583	DNA-binding transcription factor activity
Alide_1735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Alide_1740	COG0303	'Molybdopterin
Alide_1742	COG0746	molybdenum cofactor guanylyltransferase activity
Alide_1743	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Alide_1746	COG1012	belongs to the aldehyde dehydrogenase family
Alide_1748	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Alide_1749	COG0835	chemotaxis
Alide_1750	COG0840	transmembrane signaling receptor activity
Alide_1753	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Alide_1753	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Alide_1754	COG0347	Belongs to the P(II) protein family
Alide_1760	COG1595	DNA-templated transcription, initiation
Alide_1761	COG0028	Belongs to the TPP enzyme family
Alide_1762	COG0440	acetolactate synthase activity
Alide_1763	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Alide_1764	COG1183	phosphatidylcholine synthase activity
Alide_1769	COG0583	DNA-binding transcription factor activity
Alide_1771	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Alide_1773	COG1414	Transcriptional regulator
Alide_1774	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Alide_1775	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Alide_1775	COG0506	proline dehydrogenase activity
Alide_1775	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Alide_1779	COG1024	Enoyl-CoA hydratase
Alide_1780	COG1250	3-hydroxyacyl-CoA dehydrogenase
Alide_1783	COG2022	thiamine diphosphate biosynthetic process
Alide_1786	COG0351	phosphomethylpyrimidine kinase
Alide_1789	COG0492	ferredoxin-NADP+ reductase activity
Alide_1790	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Alide_1792	COG0175	sulfate reduction
Alide_1793	COG0175	sulfate reduction
Alide_1796	COG0730	response to heat
Alide_1797	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Alide_1797	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Alide_1798	COG2860	membrane
Alide_1799	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Alide_1800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Alide_1805	COG0183	Belongs to the thiolase family
Alide_1806	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_1808	COG0559	Belongs to the binding-protein-dependent transport system permease family
Alide_1811	COG0410	ABC transporter
Alide_1813	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_1840	COG0582	viral genome integration into host DNA
Alide_1841	COG1959	2 iron, 2 sulfur cluster binding
Alide_1844	COG0688	phosphatidylethanolamine metabolic process
Alide_1845	COG0517	IMP dehydrogenase activity
Alide_1845	COG1125	glycine betaine transport
Alide_1846	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Alide_1847	COG3706	GGDEF domain
Alide_1849	COG0776	regulation of translation
Alide_1851	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Alide_1852	COG0287	Prephenate dehydrogenase
Alide_1853	COG1605	Chorismate mutase
Alide_1853	COG0077	Prephenate dehydratase
Alide_1854	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Alide_1857	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Alide_1860	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Alide_1873	COG4372	Transposase
Alide_1879	COG0583	DNA-binding transcription factor activity
Alide_1880	COG2066	Belongs to the glutaminase family
Alide_1881	COG1473	amidohydrolase
Alide_1882	COG0477	Major facilitator Superfamily
Alide_1890	COG2130	NADP-dependent
Alide_1893	COG2814	Major facilitator Superfamily
Alide_1894	COG0415	Belongs to the DNA photolyase family
Alide_1896	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Alide_1897	COG0583	DNA-binding transcription factor activity
Alide_1902	COG2828	Protein conserved in bacteria
Alide_1906	COG3800	Transcriptional regulator
Alide_1906	COG1396	sequence-specific DNA binding
Alide_1910	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Alide_1911	COG0642	Histidine kinase
Alide_1913	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_1921	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Alide_1922	COG1011	Hydrolase
Alide_1927	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Alide_1928	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Alide_1929	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Alide_1930	COG0741	lytic transglycosylase activity
Alide_1933	COG0557	exoribonuclease II activity
Alide_1934	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_1936	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Alide_1936	COG2010	Cytochrome c
Alide_1937	COG3118	belongs to the thioredoxin family
Alide_1938	COG0779	Required for maturation of 30S ribosomal subunits
Alide_1939	COG0195	Participates in both transcription termination and antitermination
Alide_1940	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Alide_1941	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Alide_1942	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Alide_1945	COG1024	Enoyl-CoA hydratase
Alide_1949	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Alide_1950	COG2867	negative regulation of translational initiation
Alide_1954	COG0519	Catalyzes the synthesis of GMP from XMP
Alide_1954	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Alide_1955	COG0582	viral genome integration into host DNA
Alide_1956	COG0372	Belongs to the citrate synthase family
Alide_1957	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Alide_1958	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Alide_1959	COG1053	succinate dehydrogenase
Alide_1960	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Alide_1961	COG2009	succinate dehydrogenase
Alide_1962	COG2188	Transcriptional regulator
Alide_1963	COG0039	L-malate dehydrogenase activity
Alide_1964	COG4106	trans-aconitate 2-methyltransferase activity
Alide_1966	COG1049	propionate catabolic process, 2-methylcitrate cycle
Alide_1967	COG0583	DNA-binding transcription factor activity
Alide_1968	COG1960	acyl-CoA dehydrogenase activity
Alide_1970	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_1971	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Alide_1975	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Alide_1978	COG3608	succinylglutamate desuccinylase aspartoacylase
Alide_1978	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Alide_1984	COG0463	Glycosyl transferase, family 2
Alide_1989	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Alide_1992	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Alide_1993	COG1845	cytochrome c oxidase, subunit III
Alide_1994	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Alide_1995	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Alide_1996	COG0477	Major facilitator Superfamily
Alide_2000	COG0824	Thioesterase
Alide_2001	COG0436	Aminotransferase
Alide_2002	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Alide_2003	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Alide_2007	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_2008	COG2918	glutathione biosynthetic process
Alide_2009	COG1289	transmembrane transporter activity
Alide_2011	COG0251	oxidation-reduction process
Alide_2017	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Alide_2019	COG0564	pseudouridine synthase activity
Alide_2030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Alide_2032	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Alide_2035	COG3384	dioxygenase
Alide_2036	COG0400	carboxylic ester hydrolase activity
Alide_2038	COG1522	sequence-specific DNA binding
Alide_2040	COG0154	amidase activity
Alide_2078	COG4383	Mu-like prophage protein gp29
Alide_2079	COG2369	cell adhesion
Alide_2083	COG4397	Mu-like prophage major head subunit gpT
Alide_2091	COG1196	nuclear chromosome segregation
Alide_2104	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_2105	COG0583	DNA-binding transcription factor activity
Alide_2106	COG2186	Transcriptional regulator
Alide_2107	COG2271	Major facilitator Superfamily
Alide_2108	COG2084	Dehydrogenase
Alide_2109	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Alide_2110	COG3395	kinase activity
Alide_2111	COG0235	Class ii aldolase
Alide_2112	COG3622	Belongs to the hyi family
Alide_2113	COG3228	Belongs to the MtfA family
Alide_2114	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Alide_2119	COG0215	cysteine-tRNA ligase activity
Alide_2122	COG0037	tRNA processing
Alide_2123	COG0527	aspartate kinase activity
Alide_2130	COG1136	(ABC) transporter
Alide_2131	COG2951	lytic endotransglycosylase activity
Alide_2132	COG2925	Exonuclease
Alide_2133	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Alide_2134	COG0628	permease
Alide_2136	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Alide_2138	COG0217	transcriptional regulatory protein
Alide_2141	COG1271	oxidase subunit
Alide_2142	COG1294	oxidase, subunit
Alide_2144	COG1346	cytolysis
Alide_2146	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Alide_2147	COG0625	glutathione transferase activity
Alide_2148	COG0433	COG0433 Predicted ATPase
Alide_2149	COG0217	transcriptional regulatory protein
Alide_2150	COG0151	Belongs to the GarS family
Alide_2151	COG0408	coproporphyrinogen oxidase activity
Alide_2152	COG0799	negative regulation of ribosome biogenesis
Alide_2153	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Alide_2154	COG0424	maF-like protein
Alide_2160	COG3391	amine dehydrogenase activity
Alide_2161	COG2010	Cytochrome c
Alide_2163	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Alide_2163	COG1648	precorrin-2 dehydrogenase activity
Alide_2164	COG1530	ribonuclease E activity
Alide_2165	COG3706	GGDEF domain
Alide_2167	COG0436	Aminotransferase
Alide_2168	COG0583	DNA-binding transcription factor activity
Alide_2172	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Alide_2176	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Alide_2182	COG0589	response to stress
Alide_2185	COG0183	Belongs to the thiolase family
Alide_2186	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_2189	COG0545	Peptidyl-prolyl cis-trans isomerase
Alide_2190	COG2197	response regulator
Alide_2198	COG1595	DNA-templated transcription, initiation
Alide_2200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Alide_2201	COG3048	D-serine ammonia-lyase activity
Alide_2202	COG1739	Uncharacterized protein family UPF0029
Alide_2207	COG1959	2 iron, 2 sulfur cluster binding
Alide_2208	COG1104	cysteine desulfurase activity
Alide_2209	COG0822	iron-sulfur transferase activity
Alide_2212	COG0443	Heat shock 70 kDa protein
Alide_2213	COG0633	Ferredoxin
Alide_2214	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Alide_2215	COG0579	oxidoreductase
Alide_2219	COG0167	dihydroorotate dehydrogenase activity
Alide_2220	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Alide_2223	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Alide_2224	COG4566	intracellular signal transduction
Alide_2226	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Alide_2227	COG0508	dehydrogenase complex catalyzes the overall conversion of
Alide_2228	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Alide_2233	COG0583	DNA-binding transcription factor activity
Alide_2234	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Alide_2235	COG2079	MmgE PrpD family protein
Alide_2236	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_2243	COG0791	NLP P60 protein
Alide_2244	COG1113	amino acid transport
Alide_2246	COG2814	Major facilitator Superfamily
Alide_2248	COG1742	UPF0060 membrane protein
Alide_2250	COG1196	nuclear chromosome segregation
Alide_2252	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Alide_2253	COG1752	Esterase of the alpha-beta hydrolase superfamily
Alide_2261	COG3243	poly(R)-hydroxyalkanoic acid synthase
Alide_2262	COG0183	Belongs to the thiolase family
Alide_2263	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_2264	COG0488	(ABC) transporter
Alide_2266	COG1960	acyl-CoA dehydrogenase activity
Alide_2267	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_2268	COG0583	DNA-binding transcription factor activity
Alide_2269	COG2890	protein-(glutamine-N5) methyltransferase activity
Alide_2270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Alide_2272	COG2171	N-acyltransferase activity
Alide_2274	COG2878	Part of a membrane complex involved in electron transport
Alide_2279	COG1309	transcriptional regulator
Alide_2281	COG1022	Amp-dependent synthetase and ligase
Alide_2282	COG1802	Transcriptional regulator
Alide_2283	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Alide_2285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_2288	COG1703	isobutyryl-CoA mutase activity
Alide_2289	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Alide_2290	COG0439	Biotin carboxylase
Alide_2292	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Alide_2295	COG0642	Histidine kinase
Alide_2298	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Alide_2301	COG0446	pyridine nucleotide-disulphide oxidoreductase
Alide_2302	COG1538	Outer membrane efflux protein
Alide_2305	COG0640	Transcriptional regulator
Alide_2309	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_2312	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_2319	COG0745	RESPONSE REGULATOR receiver
Alide_2320	COG0642	Histidine kinase
Alide_2321	COG1024	Enoyl-CoA hydratase
Alide_2323	COG1064	alcohol dehydrogenase
Alide_2324	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_2325	COG1960	acyl-CoA dehydrogenase activity
Alide_2327	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_2331	COG4120	Belongs to the binding-protein-dependent transport system permease family
Alide_2333	COG3284	Transcriptional regulator
Alide_2338	COG0508	dehydrogenase complex catalyzes the overall conversion of
Alide_2339	COG0022	dehydrogenase e1 component
Alide_2339	COG0508	dehydrogenase complex catalyzes the overall conversion of
Alide_2340	COG0022	dehydrogenase e1 component
Alide_2341	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Alide_2343	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Alide_2346	COG1234	tRNA 3'-trailer cleavage
Alide_2347	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Alide_2348	COG0509	glycine decarboxylation via glycine cleavage system
Alide_2349	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Alide_2349	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Alide_2351	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Alide_2352	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Alide_2356	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Alide_2359	COG1960	acyl-CoA dehydrogenase activity
Alide_2363	COG0123	including yeast histone deacetylase and acetoin utilization protein
Alide_2364	COG0714	Associated with various cellular activities
Alide_2367	COG2951	lytic endotransglycosylase activity
Alide_2368	COG3958	Transketolase
Alide_2369	COG3959	Transketolase, thiamine diphosphate binding domain
Alide_2370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Alide_2372	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Alide_2373	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_2374	COG0583	DNA-binding transcription factor activity
Alide_2376	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Alide_2377	COG0583	DNA-binding transcription factor activity
Alide_2379	COG0683	leucine binding
Alide_2381	COG0577	efflux transmembrane transporter activity
Alide_2381	COG1136	(ABC) transporter
Alide_2382	COG1136	(ABC) transporter
Alide_2382	COG0577	efflux transmembrane transporter activity
Alide_2383	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Alide_2385	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Alide_2386	COG0516	GMP reductase activity
Alide_2386	COG0517	IMP dehydrogenase activity
Alide_2389	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Alide_2390	COG1538	Outer membrane efflux protein
Alide_2391	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Alide_2393	COG0243	molybdopterin cofactor binding
Alide_2394	COG2223	nitrite transmembrane transporter activity
Alide_2396	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Alide_2398	COG1607	acyl-coa hydrolase
Alide_2399	COG2081	HI0933 family
Alide_2406	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Alide_2407	COG0508	dehydrogenase complex catalyzes the overall conversion of
Alide_2408	COG1024	Enoyl-CoA hydratase
Alide_2409	COG0022	dehydrogenase e1 component
Alide_2410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Alide_2415	COG1960	acyl-CoA dehydrogenase activity
Alide_2419	COG0822	iron-sulfur transferase activity
Alide_2420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Alide_2422	COG0396	ATPase activity
Alide_2423	COG0719	Fe-S assembly protein
Alide_2424	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Alide_2426	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Alide_2430	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Alide_2430	COG2755	lipolytic protein G-D-S-L family
Alide_2431	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Alide_2431	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Alide_2433	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Alide_2440	COG0683	leucine binding
Alide_2441	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Alide_2443	COG2186	Transcriptional regulator
Alide_2444	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Alide_2445	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Alide_2446	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Alide_2447	COG4208	sulfate ABC transporter
Alide_2449	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Alide_2452	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Alide_2454	COG1464	Belongs to the NlpA lipoprotein family
Alide_2455	COG2011	ABC-type metal ion transport system permease component
Alide_2456	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Alide_2458	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Alide_2459	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Alide_2460	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Alide_2463	COG4149	molybdate abc transporter
Alide_2468	COG1120	ATPase activity
Alide_2469	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Alide_2472	COG4206	TonB-dependent receptor
Alide_2478	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Alide_2480	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Alide_2481	COG0254	rRNA binding
Alide_2483	COG0534	Mate efflux family protein
Alide_2486	COG0704	Plays a role in the regulation of phosphate uptake
Alide_2487	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Alide_2488	COG0581	inorganic phosphate transmembrane transporter activity
Alide_2489	COG0573	inorganic phosphate transmembrane transporter activity
Alide_2490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Alide_2496	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Alide_2498	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Alide_2499	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Alide_2500	COG1534	Rna-binding protein
Alide_2503	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Alide_2504	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Alide_2505	COG0505	Belongs to the CarA family
Alide_2506	COG0789	Transcriptional regulator
Alide_2507	COG0776	regulation of translation
Alide_2508	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Alide_2508	COG0072	phenylalanine-tRNA ligase activity
Alide_2509	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Alide_2510	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Alide_2511	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Alide_2512	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Alide_2513	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Alide_2524	COG3193	protein, possibly involved in utilization of glycolate and propanediol
Alide_2525	COG0670	Belongs to the BI1 family
Alide_2529	COG2076	Multidrug Resistance protein
Alide_2532	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Alide_2534	COG5507	3-demethylubiquinone-9 3-methyltransferase
Alide_2541	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Alide_2542	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Alide_2543	COG4181	ATPase activity
Alide_2546	COG0626	cystathionine gamma-synthase activity
Alide_2549	COG3706	GGDEF domain
Alide_2550	COG0455	bacterial-type flagellum organization
Alide_2551	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Alide_2553	COG2133	pyrroloquinoline quinone binding
Alide_2554	COG0583	DNA-binding transcription factor activity
Alide_2557	COG1960	acyl-CoA dehydrogenase activity
Alide_2562	COG0133	tryptophan synthase activity
Alide_2563	COG3171	Protein conserved in bacteria
Alide_2564	COG2721	sulfolactate sulfo-lyase activity
Alide_2565	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_2566	COG4948	Mandelate Racemase Muconate Lactonizing
Alide_2568	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_2569	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Alide_2571	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Alide_2572	COG4948	Mandelate Racemase Muconate Lactonizing
Alide_2574	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Alide_2575	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Alide_2576	COG1741	Belongs to the pirin family
Alide_2577	COG0583	DNA-binding transcription factor activity
Alide_2578	COG0493	'glutamate synthase
Alide_2578	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Alide_2579	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Alide_2580	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Alide_2581	COG3706	GGDEF domain
Alide_2582	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Alide_2583	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Alide_2585	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Alide_2586	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Alide_2587	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Alide_2588	COG1802	Transcriptional regulator
Alide_2589	COG0564	pseudouridine synthase activity
Alide_2590	COG1042	CoA-binding domain protein
Alide_2590	COG0045	succinate-CoA ligase (ADP-forming) activity
Alide_2590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Alide_2595	COG3718	enzyme involved in inositol metabolism
Alide_2598	COG2169	Transcriptional regulator
Alide_2602	COG1619	proteins homologs of microcin C7 resistance protein MccF
Alide_2603	COG0590	tRNA wobble adenosine to inosine editing
Alide_2605	COG0826	peptidase U32
Alide_2607	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Alide_2608	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Alide_2609	COG3047	cAMP biosynthetic process
Alide_2610	COG2354	Protein conserved in bacteria
Alide_2611	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Alide_2611	COG0047	phosphoribosylformylglycinamidine synthase activity
Alide_2612	COG0024	Methionine aminopeptidase
Alide_2614	COG2233	PERMEase
Alide_2615	COG0242	peptide deformylase activity
Alide_2616	COG2832	Protein of unknown function (DUF454)
Alide_2623	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Alide_2624	COG1570	exodeoxyribonuclease VII activity
Alide_2625	COG0811	peptide transport
Alide_2627	COG1663	tetraacyldisaccharide 4'-kinase activity
Alide_2628	COG2835	tetraacyldisaccharide 4'-kinase activity
Alide_2629	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Alide_2630	COG0563	adenylate kinase activity
Alide_2631	COG0252	asparaginase activity
Alide_2632	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Alide_2634	COG1643	Atp-dependent helicase
Alide_2635	COG0183	Belongs to the thiolase family
Alide_2636	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_2637	COG1268	BioY protein
Alide_2639	COG1122	ATPase activity
Alide_2642	COG0346	lactoylglutathione lyase activity
Alide_2643	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Alide_2644	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Alide_2648	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Alide_2649	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_2650	COG3485	protocatechuate 3,4-dioxygenase
Alide_2653	COG0800	Aldolase
Alide_2655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Alide_2656	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Alide_2657	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Alide_2658	COG3265	gluconokinase activity
Alide_2659	COG1609	Transcriptional regulator
Alide_2660	COG0542	response to heat
Alide_2661	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Alide_2664	COG1199	ATP-dependent helicase activity
Alide_2665	COG0631	protein serine/threonine phosphatase activity
Alide_2667	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Alide_2668	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Alide_2669	COG0508	dehydrogenase complex catalyzes the overall conversion of
Alide_2670	COG0567	Dehydrogenase, E1 component
Alide_2671	COG0628	permease
Alide_2676	COG0589	response to stress
Alide_2677	COG4172	Belongs to the ABC transporter superfamily
Alide_2678	COG4239	(ABC) transporter, permease
Alide_2679	COG4174	ABC transporter (Permease)
Alide_2684	COG2841	Protein conserved in bacteria
Alide_2685	COG1793	dna ligase
Alide_2686	COG0861	Integral membrane protein TerC family
Alide_2687	COG1982	Orn Lys Arg decarboxylase major
Alide_2690	COG0583	DNA-binding transcription factor activity
Alide_2691	COG0028	Belongs to the TPP enzyme family
Alide_2692	COG1742	UPF0060 membrane protein
Alide_2694	COG0431	NADPH-dependent FMN reductase
Alide_2695	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Alide_2701	COG1230	cation diffusion facilitator family transporter
Alide_2703	COG0121	glutamine amidotransferase
Alide_2705	COG0183	Belongs to the thiolase family
Alide_2722	COG1192	Involved in chromosome partitioning
Alide_2725	COG0583	DNA-binding transcription factor activity
Alide_2726	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Alide_2740	COG2132	Multicopper oxidase
Alide_2742	COG2205	protein histidine kinase activity
Alide_2745	COG2132	Multicopper oxidase
Alide_2750	COG2217	Heavy metal translocating P-type atpase
Alide_2752	COG0583	DNA-binding transcription factor activity
Alide_2758	COG0583	DNA-binding transcription factor activity
Alide_2759	COG0473	3-isopropylmalate dehydrogenase activity
Alide_2760	COG1752	Esterase of the alpha-beta hydrolase superfamily
Alide_2763	COG2721	sulfolactate sulfo-lyase activity
Alide_2764	COG1012	belongs to the aldehyde dehydrogenase family
Alide_2767	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Alide_2770	COG1228	amidohydrolase
Alide_2772	COG1126	abc transporter atp-binding protein
Alide_2773	COG0765	amino acid transport
Alide_2776	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Alide_2777	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Alide_2779	COG2986	histidine ammonia-lyase
Alide_2780	COG2188	Transcriptional regulator
Alide_2782	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Alide_2786	COG0583	DNA-binding transcription factor activity
Alide_2789	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Alide_2790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_2791	COG0583	DNA-binding transcription factor activity
Alide_2793	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Alide_2795	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Alide_2798	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Alide_2804	COG0753	catalase activity
Alide_2805	COG3634	alkyl hydroperoxide reductase activity
Alide_2810	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Alide_2811	COG0181	hydroxymethylbilane synthase activity
Alide_2815	COG3278	Belongs to the heme-copper respiratory oxidase family
Alide_2820	COG0525	valine-tRNA ligase activity
Alide_2821	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Alide_2822	COG0425	Belongs to the sulfur carrier protein TusA family
Alide_2823	COG2816	NAD+ diphosphatase activity
Alide_2826	COG2948	multi-organism process
Alide_2827	COG3504	Conjugal transfer protein
Alide_2832	COG3451	type IV secretory pathway VirB4
Alide_2834	COG3838	Conjugal transfer protein Trbc
Alide_2835	COG4962	Type ii secretion system protein e
Alide_2839	COG0583	DNA-binding transcription factor activity
Alide_2842	COG0589	response to stress
Alide_2843	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_2846	COG1309	transcriptional regulator
Alide_2848	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Alide_2849	COG1131	(ABC) transporter
Alide_2850	COG0842	Transport permease protein
Alide_2851	COG0842	Transport permease protein
Alide_2853	COG1454	alcohol dehydrogenase
Alide_2855	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Alide_2856	COG1611	Belongs to the LOG family
Alide_2860	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Alide_2869	COG1477	protein flavinylation
Alide_2871	COG3038	cytochrome b561
Alide_2876	COG4959	Type IV secretory pathway protease TraF
Alide_2883	COG1024	Enoyl-CoA hydratase
Alide_2886	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Alide_2888	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Alide_2889	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Alide_2890	COG1024	Enoyl-CoA hydratase
Alide_2892	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Alide_2895	COG0322	excinuclease ABC activity
Alide_2901	COG1960	acyl-CoA dehydrogenase activity
Alide_2902	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_2907	COG0559	Belongs to the binding-protein-dependent transport system permease family
Alide_2911	COG1024	Enoyl-CoA hydratase
Alide_2912	COG1012	belongs to the aldehyde dehydrogenase family
Alide_2913	COG1012	belongs to the aldehyde dehydrogenase family
Alide_2917	COG1012	belongs to the aldehyde dehydrogenase family
Alide_2918	COG1063	alcohol dehydrogenase
Alide_2922	COG0411	ABC transporter
Alide_2927	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
Alide_2930	COG1960	acyl-CoA dehydrogenase activity
Alide_2931	COG0583	DNA-binding transcription factor activity
Alide_2933	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_2935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Alide_2936	COG0183	Belongs to the thiolase family
Alide_2939	COG1960	acyl-CoA dehydrogenase activity
Alide_2949	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_2951	COG1024	Enoyl-CoA hydratase
Alide_2952	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_2954	COG1960	acyl-CoA dehydrogenase activity
Alide_2958	COG0183	Belongs to the thiolase family
Alide_2961	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_2964	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_2969	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_2970	COG1902	pentaerythritol trinitrate reductase activity
Alide_2970	COG0446	pyridine nucleotide-disulphide oxidoreductase
Alide_2972	COG0411	ABC transporter
Alide_2974	COG0559	Belongs to the binding-protein-dependent transport system permease family
Alide_2977	COG0778	Nitroreductase
Alide_2980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_2981	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_2983	COG2030	dehydratase
Alide_2984	COG2301	Belongs to the HpcH HpaI aldolase family
Alide_2985	COG1309	transcriptional regulator
Alide_2986	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Alide_2987	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Alide_2988	COG0740	serine-type endopeptidase activity
Alide_2989	COG0544	peptidyl-prolyl cis-trans isomerase activity
Alide_2990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Alide_2993	COG1562	ergosterol biosynthetic process
Alide_2994	COG0840	transmembrane signaling receptor activity
Alide_2995	COG1233	COG1233 Phytoene dehydrogenase and related
Alide_2997	COG1295	ribonuclease BN
Alide_2999	COG0277	FAD linked oxidase domain protein
Alide_3000	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Alide_3003	COG1360	Flagellar Motor Protein
Alide_3007	COG3293	Transposase
Alide_3008	COG0745	RESPONSE REGULATOR receiver
Alide_3009	COG2205	protein histidine kinase activity
Alide_3011	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Alide_3012	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Alide_3014	COG0708	Exodeoxyribonuclease III
Alide_3016	COG3852	Histidine kinase
Alide_3024	COG1187	pseudouridine synthase activity
Alide_3026	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Alide_3027	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Alide_3029	COG0330	HflC and HflK could
Alide_3030	COG0330	HflC and HflK could
Alide_3031	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Alide_3032	COG1923	regulation of RNA biosynthetic process
Alide_3033	COG1160	GTP binding
Alide_3034	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Alide_3036	COG0124	histidyl-tRNA synthetase
Alide_3037	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Alide_3040	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Alide_3041	COG0105	UTP biosynthetic process
Alide_3042	COG1187	pseudouridine synthase activity
Alide_3043	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Alide_3044	COG0564	pseudouridine synthase activity
Alide_3046	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Alide_3047	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Alide_3048	COG3706	GGDEF domain
Alide_3048	COG0745	RESPONSE REGULATOR receiver
Alide_3049	COG3540	Alkaline phosphatase
Alide_3052	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_3055	COG0179	Fumarylacetoacetate (FAA) hydrolase
Alide_3057	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Alide_3058	COG1538	Outer membrane efflux protein
Alide_3060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Alide_3063	COG1968	undecaprenyl-diphosphatase activity
Alide_3066	COG2972	Histidine kinase
Alide_3067	COG3279	Response regulator of the LytR AlgR family
Alide_3068	COG2814	Major facilitator Superfamily
Alide_3070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Alide_3071	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Alide_3072	COG2916	Histone family protein nucleoid-structuring protein H-NS
Alide_3073	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Alide_3075	COG3245	cytochrome
Alide_3077	COG4263	nitrous-oxide reductase activity
Alide_3081	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Alide_3084	COG0513	Belongs to the DEAD box helicase family
Alide_3085	COG2321	neutral zinc metallopeptidase
Alide_3086	COG0717	Belongs to the dCTP deaminase family
Alide_3091	COG0405	Gamma-glutamyltransferase
Alide_3094	COG2084	Dehydrogenase
Alide_3095	COG3622	Belongs to the hyi family
Alide_3096	COG3960	tartronate-semialdehyde synthase activity
Alide_3097	COG0583	DNA-binding transcription factor activity
Alide_3099	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Alide_3104	COG0583	DNA-binding transcription factor activity
Alide_3105	COG2186	Transcriptional regulator
Alide_3108	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Alide_3110	COG0840	transmembrane signaling receptor activity
Alide_3111	COG2233	PERMEase
Alide_3112	COG0281	malic enzyme
Alide_3112	COG0280	phosphate acetyltransferase
Alide_3117	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Alide_3118	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Alide_3119	COG1012	belongs to the aldehyde dehydrogenase family
Alide_3120	COG0305	Participates in initiation and elongation during chromosome replication
Alide_3121	COG0359	binds to the 23S rRNA
Alide_3122	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Alide_3123	COG2965	DNA replication, synthesis of RNA primer
Alide_3124	COG0360	Binds together with S18 to 16S ribosomal RNA
Alide_3125	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Alide_3126	COG0443	Heat shock 70 kDa protein
Alide_3127	COG0484	heat shock protein binding
Alide_3129	COG3033	Beta-eliminating lyase
Alide_3135	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Alide_3137	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Alide_3139	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Alide_3140	COG5510	response to toxic substance
Alide_3141	COG0066	3-isopropylmalate dehydratase activity
Alide_3142	COG0473	3-isopropylmalate dehydrogenase activity
Alide_3145	COG0101	tRNA pseudouridine synthase activity
Alide_3146	COG0135	phosphoribosylanthranilate isomerase activity
Alide_3147	COG0133	tryptophan synthase activity
Alide_3148	COG0159	tryptophan synthase activity
Alide_3149	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Alide_3150	COG0762	integral membrane protein
Alide_3154	COG0110	maltose O-acetyltransferase activity
Alide_3155	COG0438	transferase activity, transferring glycosyl groups
Alide_3158	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Alide_3159	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Alide_3160	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Alide_3163	COG0559	Belongs to the binding-protein-dependent transport system permease family
Alide_3168	COG1472	Belongs to the glycosyl hydrolase 3 family
Alide_3169	COG0736	holo-[acyl-carrier-protein] synthase activity
Alide_3170	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Alide_3171	COG1381	Involved in DNA repair and RecF pathway recombination
Alide_3172	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Alide_3173	COG0571	ribonuclease III activity
Alide_3176	COG0481	GTPase activity
Alide_3177	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Alide_3182	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Alide_3183	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Alide_3184	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_3186	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Alide_3187	COG0416	fatty acid biosynthetic process
Alide_3188	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Alide_3189	COG1399	metal-binding, possibly nucleic acid-binding protein
Alide_3190	COG0424	maF-like protein
Alide_3191	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Alide_3192	COG0616	signal peptide processing
Alide_3192	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Alide_3195	COG0564	pseudouridine synthase activity
Alide_3196	COG1530	ribonuclease E activity
Alide_3197	COG3022	response to hydroperoxide
Alide_3199	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Alide_3199	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Alide_3200	COG0840	transmembrane signaling receptor activity
Alide_3201	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Alide_3202	COG0583	DNA-binding transcription factor activity
Alide_3204	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_3205	COG1960	acyl-CoA dehydrogenase activity
Alide_3207	COG1304	FMN binding
Alide_3208	COG2885	chlorophyll binding
Alide_3209	COG5001	Diguanylate cyclase
Alide_3209	COG3300	MHYT domain
Alide_3211	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Alide_3213	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_3216	COG1960	acyl-CoA dehydrogenase activity
Alide_3217	COG0252	asparaginase activity
Alide_3220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Alide_3222	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_3223	COG0165	Argininosuccinate lyase
Alide_3224	COG3275	phosphorelay sensor kinase activity
Alide_3226	COG2719	SpoVR family
Alide_3227	COG2718	Belongs to the UPF0229 family
Alide_3228	COG2766	serine protein kinase
Alide_3229	COG1959	2 iron, 2 sulfur cluster binding
Alide_3230	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
Alide_3231	COG2346	COG2346, Truncated hemoglobins
Alide_3234	COG0667	Aldo Keto reductase
Alide_3236	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Alide_3238	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_3239	COG0154	amidase activity
Alide_3241	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Alide_3243	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Alide_3244	COG1492	cobalamin metabolic process
Alide_3246	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Alide_3253	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Alide_3253	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Alide_3254	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Alide_3256	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Alide_3260	COG0542	response to heat
Alide_3261	COG0314	molybdopterin synthase activity
Alide_3265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Alide_3267	COG0303	'Molybdopterin
Alide_3268	COG1763	Mo-molybdopterin cofactor biosynthetic process
Alide_3269	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Alide_3270	COG1487	ribonuclease activity
Alide_3273	COG0436	Aminotransferase
Alide_3276	COG1960	acyl-CoA dehydrogenase activity
Alide_3277	COG1960	acyl-CoA dehydrogenase activity
Alide_3281	COG0183	Belongs to the thiolase family
Alide_3283	COG0183	Belongs to the thiolase family
Alide_3284	COG1024	Enoyl-CoA hydratase
Alide_3285	COG1960	acyl-CoA dehydrogenase activity
Alide_3286	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Alide_3286	COG1042	CoA-binding domain protein
Alide_3286	COG0045	succinate-CoA ligase (ADP-forming) activity
Alide_3289	COG1024	Enoyl-CoA hydratase
Alide_3290	COG1024	Enoyl-CoA hydratase
Alide_3290	COG1250	3-hydroxyacyl-CoA dehydrogenase
Alide_3294	COG1960	acyl-CoA dehydrogenase activity
Alide_3295	COG1960	acyl-CoA dehydrogenase activity
Alide_3296	COG1024	Enoyl-CoA hydratase
Alide_3297	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
Alide_3298	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_3299	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_3300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_3302	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_3305	COG1902	pentaerythritol trinitrate reductase activity
Alide_3306	COG2226	methyltransferase
Alide_3307	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Alide_3309	COG1120	ATPase activity
Alide_3310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Alide_3314	COG4206	TonB-dependent receptor
Alide_3318	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Alide_3321	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Alide_3328	COG3278	Belongs to the heme-copper respiratory oxidase family
Alide_3332	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_3336	COG1802	Transcriptional regulator
Alide_3337	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Alide_3340	COG0129	dihydroxy-acid dehydratase activity
Alide_3341	COG0129	dihydroxy-acid dehydratase activity
Alide_3344	COG1136	(ABC) transporter
Alide_3345	COG4591	ABC-type transport system involved in lipoprotein release permease component
Alide_3347	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Alide_3348	COG0840	transmembrane signaling receptor activity
Alide_3349	COG0613	PHP domain protein
Alide_3350	COG0009	L-threonylcarbamoyladenylate synthase
Alide_3352	COG1994	Peptidase M50
Alide_3353	COG0180	Tryptophanyl-tRNA synthetase
Alide_3354	COG0745	RESPONSE REGULATOR receiver
Alide_3357	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Alide_3359	COG3781	membrane
Alide_3360	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Alide_3362	COG1253	flavin adenine dinucleotide binding
Alide_3363	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Alide_3364	COG1047	Peptidyl-prolyl cis-trans
Alide_3365	COG2003	Belongs to the UPF0758 family
Alide_3367	COG1193	negative regulation of DNA recombination
Alide_3369	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Alide_3370	COG0066	3-isopropylmalate dehydratase activity
Alide_3372	COG1802	Transcriptional regulator
Alide_3372	COG4626	Terminase
Alide_3377	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Alide_3378	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Alide_3382	COG0437	4 iron, 4 sulfur cluster binding
Alide_3383	COG3383	formate dehydrogenase (NAD+) activity
Alide_3389	COG3383	formate dehydrogenase (NAD+) activity
Alide_3393	COG2186	Transcriptional regulator
Alide_3394	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_3395	COG1960	acyl-CoA dehydrogenase activity
Alide_3397	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_3399	COG0489	protein tyrosine kinase activity
Alide_3402	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Alide_3405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Alide_3405	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Alide_3408	COG3135	benzoate transporter
Alide_3410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Alide_3413	COG1304	FMN binding
Alide_3414	COG0028	Belongs to the TPP enzyme family
Alide_3420	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Alide_3423	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Alide_3426	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Alide_3427	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Alide_3429	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_3434	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Alide_3435	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Alide_3437	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Alide_3438	COG0588	phosphoglycerate mutase activity
Alide_3439	COG0793	Belongs to the peptidase S41A family
Alide_3440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Alide_3442	COG2197	response regulator
Alide_3444	COG5487	UPF0391 membrane protein
Alide_3446	COG2823	Periplasmic or secreted lipoprotein
Alide_3447	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Alide_3448	COG0742	ribosomal rna small subunit methyltransferase
Alide_3449	COG0612	Peptidase, M16
Alide_3450	COG0612	Peptidase, M16
Alide_3452	COG0583	DNA-binding transcription factor activity
Alide_3453	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Alide_3455	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_3456	COG4948	Mandelate Racemase Muconate Lactonizing
Alide_3462	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Alide_3463	COG2706	6-phosphogluconolactonase activity
Alide_3467	COG0642	Histidine kinase
Alide_3469	COG3038	cytochrome b561
Alide_3475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Alide_3476	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_3477	COG1999	signal sequence binding
Alide_3478	COG0109	protoheme IX farnesyltransferase activity
Alide_3485	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Alide_3487	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Alide_3489	COG2226	methyltransferase
Alide_3490	COG1040	competence protein
Alide_3491	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Alide_3495	COG1280	lysine exporter protein (LysE YggA)
Alide_3496	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Alide_3496	COG0475	glutathione-regulated potassium exporter activity
Alide_3499	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Alide_3500	COG0066	3-isopropylmalate dehydratase activity
Alide_3506	COG1473	amidohydrolase
Alide_3508	COG0583	DNA-binding transcription factor activity
Alide_3512	COG0183	Belongs to the thiolase family
Alide_3513	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Alide_3515	COG1414	Transcriptional regulator
Alide_3519	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Alide_3521	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_3522	COG1609	Transcriptional regulator
Alide_3523	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_3535	COG3179	chitinase
Alide_3608	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Alide_3609	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Alide_3614	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Alide_3615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Alide_3615	COG0543	2 iron, 2 sulfur cluster binding
Alide_3617	COG0642	Histidine kinase
Alide_3618	COG0745	RESPONSE REGULATOR receiver
Alide_3619	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Alide_3621	COG1178	ABC-type Fe3 transport system permease component
Alide_3622	COG3842	ATPase activity
Alide_3625	COG0540	Belongs to the ATCase OTCase family
Alide_3626	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Alide_3627	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Alide_3628	COG1678	Uncharacterized ACR, COG1678
Alide_3630	COG0840	transmembrane signaling receptor activity
Alide_3634	COG1773	rubredoxin
Alide_3636	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Alide_3637	COG0138	bifunctional purine biosynthesis protein purh
Alide_3638	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
Alide_3639	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Alide_3640	COG1238	metal cluster binding
Alide_3642	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_3643	COG1473	amidohydrolase
Alide_3646	COG2205	protein histidine kinase activity
Alide_3648	COG0012	GTP binding
Alide_3649	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Alide_3650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Alide_3652	COG1024	Enoyl-CoA hydratase
Alide_3654	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Alide_3655	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Alide_3656	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Alide_3661	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Alide_3661	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Alide_3662	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Alide_3666	COG2264	protein methyltransferase activity
Alide_3667	COG0439	Biotin carboxylase
Alide_3668	COG0511	ligase activity, forming carbon-carbon bonds
Alide_3669	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Alide_3671	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Alide_3673	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Alide_3674	COG0312	modulator of DNA gyrase
Alide_3675	COG0772	Belongs to the SEDS family
Alide_3676	COG3150	esterase
Alide_3678	COG3474	cytochrome
Alide_3680	COG1595	DNA-templated transcription, initiation
Alide_3681	COG0557	exoribonuclease II activity
Alide_3683	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Alide_3684	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Alide_3688	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Alide_3691	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Alide_3693	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Alide_3696	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_3703	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Alide_3704	COG1181	Belongs to the D-alanine--D-alanine ligase family
Alide_3705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Alide_3706	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Alide_3707	COG0772	Belongs to the SEDS family
Alide_3708	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Alide_3709	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Alide_3710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Alide_3711	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Alide_3714	COG0275	rRNA processing
Alide_3715	COG2001	Belongs to the MraZ family
Alide_3716	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Alide_3717	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Alide_3719	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Alide_3720	COG0523	cobalamin synthesis protein
Alide_3722	COG2201	protein-glutamate methylesterase activity
Alide_3725	COG2201	protein-glutamate methylesterase activity
Alide_3726	COG0745	RESPONSE REGULATOR receiver
Alide_3727	COG0784	Response regulator, receiver
Alide_3727	COG3437	response regulator, receiver
Alide_3729	COG2205	protein histidine kinase activity
Alide_3729	COG5002	protein histidine kinase activity
Alide_3729	COG0784	Response regulator, receiver
Alide_3731	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Alide_3733	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Alide_3735	COG1187	pseudouridine synthase activity
Alide_3739	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Alide_3747	COG1846	Transcriptional regulator
Alide_3748	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_3749	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Alide_3751	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_3756	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_3758	COG1024	Enoyl-CoA hydratase
Alide_3759	COG1960	acyl-CoA dehydrogenase activity
Alide_3760	COG1960	acyl-CoA dehydrogenase activity
Alide_3761	COG0183	Belongs to the thiolase family
Alide_3762	COG1024	Enoyl-CoA hydratase
Alide_3762	COG1250	3-hydroxyacyl-CoA dehydrogenase
Alide_3763	COG0583	DNA-binding transcription factor activity
Alide_3774	COG4372	Transposase
Alide_3777	COG0501	Belongs to the peptidase M48B family
Alide_3779	COG0418	dihydroorotase activity
Alide_3781	COG3189	MarR family transcriptional regulator
Alide_3782	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Alide_3783	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Alide_3784	COG0683	leucine binding
Alide_3787	COG0477	Major facilitator Superfamily
Alide_3796	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Alide_3800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Alide_3801	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_3806	COG0559	Belongs to the binding-protein-dependent transport system permease family
Alide_3808	COG0410	ABC transporter
Alide_3809	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Alide_3810	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_3811	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Alide_3813	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Alide_3814	COG2203	Gaf domain
Alide_3814	COG5001	Diguanylate cyclase
Alide_3814	COG3706	GGDEF domain
Alide_3814	COG4251	negative regulation of phosphorylation
Alide_3815	COG0747	negative chemotaxis
Alide_3817	COG5002	protein histidine kinase activity
Alide_3817	COG5001	Diguanylate cyclase
Alide_3818	COG3012	SEC-C Motif Domain Protein
Alide_3828	COG1960	acyl-CoA dehydrogenase activity
Alide_3830	COG0183	Belongs to the thiolase family
Alide_3831	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
Alide_3832	COG0288	reversible hydration of carbon dioxide
Alide_3833	COG1960	acyl-CoA dehydrogenase activity
Alide_3834	COG0789	Transcriptional regulator
Alide_3836	COG2201	protein-glutamate methylesterase activity
Alide_3837	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Alide_3838	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Alide_3839	COG0835	chemotaxis
Alide_3840	COG2198	Histidine kinase
Alide_3840	COG0643	Histidine kinase
Alide_3841	COG2201	protein-glutamate methylesterase activity
Alide_3844	COG2197	response regulator
Alide_3846	COG1987	bacterial-type flagellum assembly
Alide_3847	COG1338	Plays a role in the flagellum-specific transport system
Alide_3849	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Alide_3857	COG1766	The M ring may be actively involved in energy transduction
Alide_3864	COG3754	Rhamnan synthesis protein F
Alide_3865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Alide_3867	COG1360	Flagellar Motor Protein
Alide_3868	COG0745	RESPONSE REGULATOR receiver
Alide_3869	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Alide_3871	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Alide_3874	COG1191	sigma factor activity
Alide_3877	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
Alide_3878	COG1815	bacterial-type flagellum-dependent cell motility
Alide_3879	COG1558	bacterial-type flagellum-dependent cell motility
Alide_3880	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Alide_3881	COG1749	Flagellar hook protein flgE
Alide_3883	COG4786	Flagellar basal body rod
Alide_3885	COG1706	bacterial-type flagellum-dependent cell motility
Alide_3886	COG3951	Flagellar rod assembly protein muramidase FlgJ
Alide_3886	COG1705	Flagellar rod assembly protein muramidase FlgJ
Alide_3888	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Alide_3890	COG2070	2-Nitropropane dioxygenase
Alide_3891	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Alide_3893	COG0697	spore germination
Alide_3894	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Alide_3895	COG0384	phenazine biosynthesis protein PhzF
Alide_3896	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Alide_3901	COG2203	Gaf domain
Alide_3901	COG4251	negative regulation of phosphorylation
Alide_3901	COG3706	GGDEF domain
Alide_3901	COG5001	Diguanylate cyclase
Alide_3906	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_3908	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Alide_3911	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Alide_3912	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Alide_3913	COG0183	Belongs to the thiolase family
Alide_3914	COG1024	Enoyl-CoA hydratase
Alide_3923	COG0679	Auxin Efflux Carrier
Alide_3924	COG0210	DNA helicase
Alide_3927	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Alide_3931	COG0179	Fumarylacetoacetate (FAA) hydrolase
Alide_3933	COG1802	Transcriptional regulator
Alide_3935	COG0589	response to stress
Alide_3936	COG0343	queuine tRNA-ribosyltransferase activity
Alide_3942	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Alide_3944	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_3944	COG0204	Acyl-transferase
Alide_3945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Alide_3946	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Alide_3950	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_3951	COG2072	flavoprotein involved in K transport
Alide_3956	COG2365	Tyrosine phosphatase family
Alide_3957	COG0203	ribosomal protein L17
Alide_3958	COG0202	RNA polymerase activity
Alide_3959	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Alide_3960	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Alide_3961	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Alide_3962	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Alide_3963	COG0201	protein transport
Alide_3964	COG0200	Binds to the 23S rRNA
Alide_3965	COG1841	ribosomal large subunit assembly
Alide_3966	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Alide_3967	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Alide_3968	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Alide_3969	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Alide_3970	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Alide_3971	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Alide_3972	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Alide_3973	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Alide_3974	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Alide_3976	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Alide_3979	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Alide_3980	COG0783	Belongs to the Dps family
Alide_3982	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Alide_3984	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Alide_3988	COG0583	DNA-binding transcription factor activity
Alide_3989	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Alide_3990	COG0134	indole-3-glycerol-phosphate synthase activity
Alide_3992	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Alide_3993	COG0512	Glutamine amidotransferase of anthranilate synthase
Alide_3996	COG1192	Involved in chromosome partitioning
Alide_4003	COG0629	single-stranded DNA binding
Alide_4004	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Alide_4004	COG0551	DNA topoisomerase type I activity
Alide_4029	COG2003	Belongs to the UPF0758 family
Alide_4054	COG0546	phosphoglycolate phosphatase activity
Alide_4056	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Alide_4057	COG2967	ApaG domain
Alide_4060	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Alide_4062	COG1309	transcriptional regulator
Alide_4065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Alide_4066	COG1129	ABC transporter
Alide_4066	COG0842	Transport permease protein
Alide_4067	COG0842	Transport permease protein
Alide_4069	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Alide_4070	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Alide_4072	COG0840	transmembrane signaling receptor activity
Alide_4076	COG3012	SEC-C Motif Domain Protein
Alide_4076	COG3318	Belongs to the UPF0149 family
Alide_4081	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Alide_4082	COG1137	ATPase activity
Alide_4084	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Alide_4086	COG0018	arginyl-trna synthetase
Alide_4089	COG1301	dicarboxylic acid transport
Alide_4090	COG4191	Histidine kinase
Alide_4093	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Alide_4095	COG1942	4-Oxalocrotonate Tautomerase
Alide_4097	COG0121	glutamine amidotransferase
Alide_4098	COG0189	ligase activity
Alide_4099	COG3135	benzoate transporter
Alide_4100	COG3158	transport of potassium into the cell
Alide_4102	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Alide_4103	COG0569	domain protein
Alide_4104	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Alide_4109	COG1466	dna polymerase III delta subunit
Alide_4111	COG0495	leucyl-tRNA aminoacylation
Alide_4112	COG0668	transmembrane transport
Alide_4113	COG1012	belongs to the aldehyde dehydrogenase family
Alide_4115	COG3284	Transcriptional regulator
Alide_4117	COG2199	diguanylate cyclase activity
Alide_4117	COG2200	EAL domain
Alide_4117	COG2202	Pas domain
Alide_4121	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Alide_4122	COG0735	belongs to the Fur family
Alide_4123	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Alide_4125	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Alide_4126	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Alide_4127	COG3118	belongs to the thioredoxin family
Alide_4129	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Alide_4130	COG0009	L-threonylcarbamoyladenylate synthase
Alide_4146	COG2027	D-alanyl-D-alanine carboxypeptidase
Alide_4150	COG0598	Magnesium transport protein CorA
Alide_4154	COG0318	PFAM AMP-dependent synthetase and ligase
Alide_4155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Alide_4156	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Alide_4159	COG0469	pyruvate kinase activity
Alide_4160	COG0006	proline dipeptidase activity
Alide_4161	COG1024	Enoyl-CoA hydratase
Alide_4166	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_4167	COG0583	DNA-binding transcription factor activity
Alide_4168	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Alide_4169	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Alide_4170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Alide_4172	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Alide_4173	COG0583	DNA-binding transcription factor activity
Alide_4182	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_4185	COG0583	DNA-binding transcription factor activity
Alide_4187	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_4195	COG0625	glutathione transferase activity
Alide_4196	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_4198	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Alide_4198	COG0551	DNA topoisomerase type I activity
Alide_4202	COG0604	alcohol dehydrogenase
Alide_4204	COG2030	dehydratase
Alide_4206	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Alide_4207	COG1846	Transcriptional regulator
Alide_4211	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_4212	COG0642	Histidine kinase
Alide_4215	COG1178	ABC-type Fe3 transport system permease component
Alide_4216	COG3842	ATPase activity
Alide_4217	COG1840	ABC-type Fe3 transport system, periplasmic component
Alide_4220	COG1012	belongs to the aldehyde dehydrogenase family
Alide_4222	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Alide_4223	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Alide_4224	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Alide_4227	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Alide_4228	COG2137	regulation of response to DNA damage stimulus
Alide_4230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Alide_4231	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Alide_4232	COG1862	Preprotein translocase
Alide_4234	COG1522	sequence-specific DNA binding
Alide_4235	COG2814	Major facilitator Superfamily
Alide_4236	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Alide_4239	COG4566	intracellular signal transduction
Alide_4241	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Alide_4243	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Alide_4244	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Alide_4246	COG0625	glutathione transferase activity
Alide_4248	COG4681	YaeQ
Alide_4251	COG0861	Integral membrane protein TerC family
Alide_4253	COG0583	DNA-binding transcription factor activity
Alide_4256	COG1950	PFAM Membrane protein of
Alide_4257	COG4783	chaperone-mediated protein folding
Alide_4258	COG0315	cyclic pyranopterin monophosphate synthase activity
Alide_4261	COG1234	tRNA 3'-trailer cleavage
Alide_4262	COG1716	ATPase activity
Alide_4264	COG0861	Integral membrane protein TerC family
Alide_4265	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Alide_4266	COG0045	succinate-CoA ligase (ADP-forming) activity
Alide_4267	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Alide_4268	COG0758	DNA mediated transformation
Alide_4270	COG0242	peptide deformylase activity
Alide_4272	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Alide_4275	COG0126	phosphoglycerate kinase activity
Alide_4278	COG0697	spore germination
Alide_4279	COG0284	orotidine-5'-phosphate decarboxylase activity
Alide_4285	COG2814	Major facilitator Superfamily
Alide_4286	COG0629	single-stranded DNA binding
Alide_4288	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_4292	COG1028	Short-chain dehydrogenase reductase Sdr
Alide_4294	COG1960	acyl-CoA dehydrogenase activity
Alide_4295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_4296	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Alide_4297	COG1620	l-lactate permease
Alide_4298	COG0482	sulfurtransferase activity
Alide_4299	COG0583	DNA-binding transcription factor activity
Alide_4300	COG2828	Protein conserved in bacteria
Alide_4302	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Alide_4304	COG1053	succinate dehydrogenase
Alide_4304	COG3976	FMN-binding domain protein
Alide_4308	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Alide_4311	COG0439	Biotin carboxylase
Alide_4312	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Alide_4316	COG4771	TonB-dependent receptor
Alide_4319	COG3181	Tripartite tricarboxylate transporter family receptor
Alide_4320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_4322	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Alide_4323	COG0307	riboflavin synthase, alpha
Alide_4324	COG1280	lysine exporter protein (LysE YggA)
Alide_4325	COG2205	protein histidine kinase activity
Alide_4326	COG0745	RESPONSE REGULATOR receiver
Alide_4329	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Alide_4330	COG3038	cytochrome b561
Alide_4334	COG1477	protein flavinylation
Alide_4337	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Alide_4340	COG2070	2-Nitropropane dioxygenase
Alide_4342	COG1960	acyl-CoA dehydrogenase activity
Alide_4343	COG1414	Transcriptional regulator
Alide_4344	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_4347	COG1960	acyl-CoA dehydrogenase activity
Alide_4350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Alide_4356	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Alide_4365	COG3706	GGDEF domain
Alide_4366	COG1802	Transcriptional regulator
Alide_4368	COG0559	Belongs to the binding-protein-dependent transport system permease family
Alide_4369	COG4177	L-phenylalanine transmembrane transporter activity
Alide_4371	COG0410	ABC transporter
Alide_4377	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Alide_4378	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Alide_4379	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Alide_4381	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Alide_4384	COG1196	nuclear chromosome segregation
Alide_4390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Alide_4391	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Alide_4392	COG2119	membrane
Alide_4393	COG0724	RNA recognition motif
Alide_4394	COG0724	RNA recognition motif
Alide_4395	COG0300	oxidoreductase activity
Alide_4397	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Alide_4400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Alide_4403	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Alide_4404	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Alide_4405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Alide_4411	COG0601	transmembrane transport
Alide_4413	COG4172	Belongs to the ABC transporter superfamily
Alide_4414	COG1446	asparaginase
Alide_4418	COG0747	negative chemotaxis
Alide_4419	COG0706	membrane insertase activity
Alide_4420	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Alide_4421	COG0594	ribonuclease P activity
Alide_4422	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Alide_4426	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Alide_4451	COG4584	PFAM Integrase catalytic
Alide_4460	COG2963	transposase activity
Alide_4462	COG0625	glutathione transferase activity
Alide_4463	COG1309	transcriptional regulator
Alide_4465	COG0625	glutathione transferase activity
Alide_4468	COG3041	Addiction module toxin RelE StbE family
Alide_4469	COG3077	Addiction module antitoxin, RelB DinJ family
Alide_4473	COG4962	Type ii secretion system protein e
Alide_4474	COG3838	Conjugal transfer protein Trbc
Alide_4475	COG5268	conjugation
Alide_4476	COG3451	type IV secretory pathway VirB4
Alide_4489	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Alide_4490	COG3041	Addiction module toxin RelE StbE family
Alide_4496	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Alide_4498	COG0789	Transcriptional regulator
Alide_4514	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Alide_4516	COG1192	Involved in chromosome partitioning
Alide_4520	COG2916	Histone family protein nucleoid-structuring protein H-NS
Alide_4527	COG0741	lytic transglycosylase activity
Alide_4592	COG4372	Transposase
Alide_4597	COG0616	signal peptide processing
Alide_4606	COG3253	May function as heme-dependent peroxidase
Alide_4609	COG1763	Mo-molybdopterin cofactor biosynthetic process
Alide_4619	COG4974	Belongs to the 'phage' integrase family
Alide_4620	COG1484	DNA-dependent DNA replication
Alide_4621	COG4584	PFAM Integrase catalytic
Alide_4623	COG4974	Belongs to the 'phage' integrase family
Alide_4635	COG3253	May function as heme-dependent peroxidase