locus-tag	class	description
HF896_00010	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HF896_00035	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HF896_00040	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HF896_00055	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_00075	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HF896_00080	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HF896_00105	ENOG4105C0Z	ABC transporter
HF896_00115	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_00125	ENOG4108IV0	ABC, transporter
HF896_00150	ENOG4107EFR	Flavocytochrome c
HF896_00155	ENOG41079YP	Citrate utilization protein b
HF896_00165	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HF896_00190	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HF896_00195	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HF896_00210	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_00230	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HF896_00235	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HF896_00260	ENOG4105C0Z	ABC transporter
HF896_00275	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_00285	ENOG4108IV0	ABC, transporter
HF896_00290	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HF896_00295	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HF896_00300	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HF896_00310	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_00320	ENOG4107NQ8	LysR family Transcriptional regulator
HF896_00340	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_00345	ENOG4107QX3	carboxylase
HF896_00350	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HF896_00360	ENOG4105D6E	homoserine dehydrogenase
HF896_00365	ENOG4105DVT	helicase
HF896_00375	ENOG4105K4H	Nlp p60 protein
HF896_00380	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HF896_00385	ENOG4105BZU	Histidine kinase
HF896_00395	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HF896_00400	ENOG4105D2B	acyl-CoA dehydrogenase
HF896_00405	ENOG4105CC9	acyl-Coa dehydrogenase
HF896_00440	ENOG4105DH7	May be involved in recombination (By similarity)
HF896_00475	ENOG4105C8Q	Methyl-accepting chemotaxis
HF896_00495	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HF896_00500	ENOG4105ECM	Sensor protein basS pmrB
HF896_00505	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HF896_00510	ENOG4108K3A	Glutathione S-transferase
HF896_00515	ENOG4105KRS	Proteinase inhibitor
HF896_00525	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HF896_00535	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HF896_00540	ENOG4108NIW	Leucine export protein LeuE
HF896_00545	ENOG4107QJE	Chromosome Partitioning Protein
HF896_00555	ENOG4105FA0	parb-like partition protein
HF896_00580	ENOG4105D64	Mechanosensitive ion channel
HF896_00585	ENOG4105CQB	FAD linked oxidase domain protein
HF896_00595	ENOG4108WBT	adenosyltransferase
HF896_00600	ENOG4105KA0	thioesterase Superfamily protein
HF896_00625	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HF896_00640	ENOG4105C2W	permease
HF896_00655	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HF896_00660	ENOG4105CN8	Transcriptional regulator
HF896_00670	ENOG4105X7H	acyl-CoA dehydrogenase
HF896_00675	ENOG4105D2B	acyl-CoA dehydrogenase
HF896_00685	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HF896_00705	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HF896_00710	ENOG4107QMS	site-determining protein
HF896_00715	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HF896_00720	ENOG4105EJC	lysr family transcriptional regulator
HF896_00730	ENOG4105CXK	mandelate racemase muconate lactonizing
HF896_00740	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HF896_00770	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
HF896_00780	ENOG4105C7B	Threonine dehydratase
HF896_00785	ENOG4105CSU	acyl-Coa dehydrogenase
HF896_00795	ENOG4105C3R	Methionine synthase
HF896_00800	ENOG4107RSM	transcriptional regulator
HF896_00820	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HF896_00840	ENOG4105BZU	Histidine kinase
HF896_00855	ENOG4108JUA	Transcriptional regulator
HF896_00865	ENOG4105EJQ	L-serine dehydratase
HF896_00875	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_00905	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_00910	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_00925	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
HF896_00950	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_00955	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_00970	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HF896_00990	ENOG4105ETT	transcriptional Regulator, LysR family
HF896_01000	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HF896_01010	ENOG4105DND	Transcriptional regulator
HF896_01015	ENOG4105CQB	FAD linked oxidase domain protein
HF896_01020	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_01055	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_01060	ENOG4108M9J	MaoC like domain protein
HF896_01065	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HF896_01075	ENOG4108UKI	Enoyl-CoA hydratase
HF896_01080	ENOG4105CYC	Transferase
HF896_01085	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_01110	ENOG4105ETT	transcriptional Regulator, LysR family
HF896_01120	ENOG4105CH2	amidohydrolase
HF896_01130	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_01145	ENOG4105CH2	amidohydrolase
HF896_01160	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_01175	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HF896_01185	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_01190	ENOG4107QX3	carboxylase
HF896_01195	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_01200	ENOG4105E39	Enoyl-CoA hydratase
HF896_01230	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_01235	ENOG4108M0I	Transcriptional regulator
HF896_01250	ENOG4105D82	Glutamate dehydrogenase
HF896_01260	ENOG4108ZK4	sdia-regulated domain-containing protein
HF896_01265	ENOG4105C3R	Methionine synthase
HF896_01270	ENOG4105E9M	CRISPR-associated protein, Csn1 family
HF896_01290	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HF896_01305	ENOG4105DP0	ferredoxin-NADP reductase
HF896_01310	ENOG41083Z3	extracellular ligand-binding receptor
HF896_01315	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_01320	ENOG4108IV0	ABC, transporter
HF896_01345	ENOG4105C0P	Mg chelatase subunit ChlI
HF896_01360	ENOG4105BZU	Histidine kinase
HF896_01365	ENOG4105ETT	transcriptional Regulator, LysR family
HF896_01370	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HF896_01400	ENOG4107YUH	hydrolase
HF896_01410	ENOG4108KK1	membrane protein AbrB duplication
HF896_01415	ENOG4108PGP	mmge prpd family protein
HF896_01435	ENOG4105EU8	FAD linked oxidase domain protein
HF896_01445	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HF896_01460	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
HF896_01465	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HF896_01470	ENOG4105CA0	peroxidase
HF896_01475	ENOG4108RXX	maleylacetoacetate isomerase
HF896_01480	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HF896_01490	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HF896_01500	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HF896_01535	ENOG4105EGI	Transcriptional regulator
HF896_01540	ENOG4105CBP	Major Facilitator
HF896_01545	ENOG4108RPX	mosc domain containing protein
HF896_01575	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_01580	ENOG4105JJR	Histidine kinase
HF896_01585	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HF896_01605	ENOG4105D0M	Protease HtpX homolog
HF896_01635	ENOG4105EUV	Phenol 2-monooxygenase
HF896_01695	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
HF896_01700	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
HF896_01720	ENOG4105C5X	domain protein
HF896_01725	ENOG41069M3	Transcriptional regulator
HF896_01735	ENOG4105GAK	amidohydrolase 2
HF896_01745	ENOG4105JSC	dimethylmenaquinone methyltransferase
HF896_01750	ENOG4108JQ1	Dehydrogenase
HF896_01765	ENOG4105GAK	amidohydrolase 2
HF896_01770	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
HF896_01780	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HF896_01785	ENOG4105C26	Dehydrogenase
HF896_01790	ENOG4107258	Transcriptional regulator
HF896_01810	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_01820	ENOG4105C0Z	ABC transporter
HF896_01825	ENOG4108IV0	ABC, transporter
HF896_01840	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_01845	ENOG4108R85	Short chain dehydrogenase
HF896_01855	ENOG4105CGK	Exodeoxyribonuclease III
HF896_01860	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HF896_01870	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HF896_01875	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HF896_01880	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HF896_01895	ENOG4105VQ7	Rod shape-determining protein MreD
HF896_01900	ENOG4105CJN	penicillin-binding protein
HF896_01910	ENOG4105EJ9	Membrane
HF896_01925	ENOG4105DHJ	ABC, transporter
HF896_01930	ENOG4105DY2	Paraquat-inducible protein b
HF896_01940	ENOG4105SKE	transcriptional Regulator LysR family
HF896_01945	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HF896_01955	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HF896_01960	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HF896_01970	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HF896_01975	ENOG4105CW7	secretion protein, HlyD family
HF896_01990	ENOG4105D7N	magnesium and cobalt transport protein CorA
HF896_01995	ENOG4105D52	delta-aminolevulinic acid dehydratase
HF896_02005	ENOG4108YXA	Membrane
HF896_02020	ENOG4105DHZ	alpha beta
HF896_02025	ENOG4105DZ1	carboxypeptidase
HF896_02030	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HF896_02035	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HF896_02040	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HF896_02045	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HF896_02050	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HF896_02055	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HF896_02060	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HF896_02065	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HF896_02070	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HF896_02075	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HF896_02080	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HF896_02085	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HF896_02090	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HF896_02095	ENOG41084PQ	50s ribosomal protein l29
HF896_02100	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HF896_02105	ENOG4105EHV	domain protein
HF896_02120	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HF896_02135	ENOG41080Z8	PHOSPHOCARRIER protein
HF896_02140	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HF896_02145	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HF896_02150	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HF896_02155	ENOG4108Z43	UPF0250 protein
HF896_02165	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
HF896_02170	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HF896_02180	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HF896_02185	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HF896_02190	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HF896_02195	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HF896_02200	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HF896_02220	ENOG4105EQ2	LysR family Transcriptional regulator
HF896_02250	ENOG4105MPD	Cytochrome
HF896_02255	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HF896_02260	ENOG4105BZS	acriflavin resistance protein
HF896_02265	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HF896_02295	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HF896_02305	ENOG4105PM1	preprotein translocase subunit SecE
HF896_02315	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HF896_02320	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HF896_02325	ENOG4108VZM	50s ribosomal protein L10
HF896_02330	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HF896_02335	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HF896_02340	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HF896_02350	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HF896_02360	ENOG4105ES5	Histidine kinase
HF896_02400	ENOG4106IJN	integrase catalytic domain-containing protein
HF896_02405	ENOG4105F5W	AtP-binding protein
HF896_02445	ENOG4108I5C	dEAD DEAH box helicase
HF896_02455	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HF896_02460	ENOG4105CVR	type I restriction-modification system
HF896_02545	ENOG410682P	Hypothetical protein (DUF2513)
HF896_02595	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HF896_02600	ENOG4105D5G	Transposase
HF896_02640	ENOG4107QJE	Chromosome Partitioning Protein
HF896_02665	ENOG4107STQ	Multicopper oxidase
HF896_02675	ENOG4105GR3	Histidine kinase
HF896_02685	ENOG4105E3B	Multicopper oxidase
HF896_02720	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
HF896_02755	ENOG4108IJF	Heavy metal efflux pump, CzcA
HF896_02760	ENOG4107RSM	transcriptional regulator
HF896_02865	ENOG4105VT3	DNA binding domain protein, excisionase family
HF896_02880	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HF896_02890	ENOG4108VDT	Glycosyl transferase family protein
HF896_02905	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HF896_02910	ENOG41082RQ	UPF0102 protein
HF896_02915	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HF896_02925	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HF896_02930	ENOG4105CZX	twitching motility protein
HF896_02935	ENOG4105IJJ	transcriptional regulator, crp fnr family
HF896_02940	ENOG4105CZX	twitching motility protein
HF896_02945	ENOG4105DFA	alanine racemase domain protein
HF896_02965	ENOG4105CQB	FAD linked oxidase domain protein
HF896_02995	ENOG4105BZU	Histidine kinase
HF896_03000	ENOG4105WH1	Two component transcriptional regulator luxr family
HF896_03010	ENOG4105DQQ	Major facilitator superfamily MFS_1
HF896_03015	ENOG4105CRU	nitrate reductase, alpha subunit
HF896_03020	ENOG4108IUE	nitrate reductase beta subunit
HF896_03025	ENOG4105R3A	Nitrate reductase
HF896_03030	ENOG4105D0D	Nitrate reductase 2, gamma subunit
HF896_03055	ENOG4105NSG	hemerythrin hhe cation binding domain protein
HF896_03080	ENOG4108J2R	molybdopterin oxidoreductase
HF896_03090	ENOG4105CI0	Citrate lyase
HF896_03095	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_03100	ENOG4105DJG	MaoC domain protein dehydratase
HF896_03105	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_03110	ENOG4105DJG	MaoC domain protein dehydratase
HF896_03130	ENOG4105CH2	amidohydrolase
HF896_03145	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HF896_03155	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HF896_03175	ENOG4105DZS	Phenylacetate-CoA ligase
HF896_03180	ENOG4108IV0	ABC, transporter
HF896_03195	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_03200	ENOG4105C0Z	ABC transporter
HF896_03205	ENOG4108IQE	Amp-dependent synthetase and ligase
HF896_03220	ENOG4105IJJ	transcriptional regulator, crp fnr family
HF896_03225	ENOG4105FE9	pseudouridine synthase
HF896_03230	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HF896_03245	ENOG4105E27	serine threonine protein kinase
HF896_03260	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_03275	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HF896_03300	ENOG4105CJ1	ABC, transporter
HF896_03310	ENOG4105FYV	Amp nucleosidase
HF896_03315	ENOG4105BZU	Histidine kinase
HF896_03325	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HF896_03330	ENOG4105EJ9	Membrane
HF896_03345	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_03350	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HF896_03355	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_03360	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HF896_03365	ENOG4105C9A	Phoh family
HF896_03370	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HF896_03385	ENOG4105CFG	Acts as a chaperone (By similarity)
HF896_03395	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HF896_03430	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HF896_03465	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
HF896_03475	ENOG4105BZP	glycoside hydrolase 15-related
HF896_03480	ENOG4108K4C	ec 3.1.3.12
HF896_03490	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HF896_03495	ENOG4108JUA	Transcriptional regulator
HF896_03525	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HF896_03530	ENOG4105E4C	Lytic transglycosylase catalytic
HF896_03545	ENOG4107E2E	PKHD-type hydroxylase
HF896_03555	ENOG4108ESX	Receptor
HF896_03565	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_03580	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HF896_03585	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HF896_03590	ENOG4108JU5	Magnesium and cobalt efflux protein
HF896_03600	ENOG4108YXU	transcriptional regulator AsnC family
HF896_03610	ENOG4105MIR	Phenylalanine 4-monooxygenase
HF896_03615	ENOG4107R0V	Pyruvate dehydrogenase
HF896_03620	ENOG4105CPP	Dehydrogenase, E1 component
HF896_03625	ENOG4107QSN	dihydrolipoamide acetyltransferase
HF896_03630	ENOG4107QN2	dihydrolipoyl dehydrogenase
HF896_03635	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
HF896_03640	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HF896_03645	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HF896_03650	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HF896_03665	ENOG4109066	lysm domain bon superfamily protein
HF896_03670	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HF896_03675	ENOG4108IG5	Transcriptional regulator
HF896_03690	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HF896_03695	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HF896_03700	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HF896_03710	ENOG4105H63	Glycosyl transferase, family 2
HF896_03715	ENOG4107QHF	type ii secretion system protein e
HF896_03720	ENOG4105D7Q	type ii secretion system
HF896_03745	ENOG4105UV2	general secretion pathway protein K
HF896_03765	ENOG4105GVR	general secretion pathway protein D
HF896_03795	ENOG4106WTF	Glycosyl transferase, family 2
HF896_03805	ENOG4105MFV	ABC-2 type transporter
HF896_03810	ENOG4105EY8	ABC transporter
HF896_03820	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HF896_03825	ENOG4105E4C	Lytic transglycosylase catalytic
HF896_03835	ENOG4105CAS	nag kinase
HF896_03840	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HF896_03850	ENOG4105CSU	acyl-Coa dehydrogenase
HF896_03865	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_03875	ENOG41060WC	Enoyl-CoA hydratase
HF896_03885	ENOG4105NAU	thioesterase Superfamily protein
HF896_03890	ENOG4108JJ7	ABC transporter
HF896_03915	ENOG4105HEI	LysR family (Transcriptional regulator
HF896_03925	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HF896_03930	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HF896_03935	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
HF896_03940	ENOG4107YNJ	LysR family Transcriptional regulator
HF896_03945	ENOG4107RP9	extracellular solute-binding protein, family 3
HF896_03950	ENOG4105EAD	ABC transporter
HF896_03955	ENOG4105DRP	amino acid AbC transporter
HF896_03960	ENOG4105CDA	abc transporter atp-binding protein
HF896_03965	ENOG4107QWB	Ornithine cyclodeaminase
HF896_03975	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HF896_03985	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HF896_03995	ENOG4105SYT	Methylenetetrahydrofolate reductase
HF896_04005	ENOG4105D6S	protein involved in catabolism of external DNA
HF896_04010	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
HF896_04015	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HF896_04020	ENOG4108UJD	30S ribosomal protein S9
HF896_04025	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HF896_04040	ENOG4106IJN	integrase catalytic domain-containing protein
HF896_04045	ENOG4105F5W	AtP-binding protein
HF896_04090	ENOG4106H6R	UPF0380 protein
HF896_04145	ENOG4107QJE	Chromosome Partitioning Protein
HF896_04170	ENOG4105W1Y	Transcriptional regulator
HF896_04190	ENOG4105GR3	Histidine kinase
HF896_04225	ENOG4105CN8	Transcriptional regulator
HF896_04260	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HF896_04265	ENOG4105DR5	peptidase
HF896_04275	ENOG4105ETT	transcriptional Regulator, LysR family
HF896_04280	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HF896_04285	ENOG4105C08	Histidine kinase
HF896_04300	ENOG4105F7P	transcriptional regulator AsnC family
HF896_04315	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HF896_04320	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HF896_04325	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HF896_04330	ENOG4105BZU	Histidine kinase
HF896_04360	ENOG4108QV3	biosynthesis protein
HF896_04395	ENOG4105CAQ	asparagine synthetase
HF896_04420	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HF896_04450	ENOG4105K64	Glycosyl transferase, family 2
HF896_04495	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_04505	ENOG41062D9	Histidine kinase
HF896_04510	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HF896_04525	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
HF896_04535	ENOG4105DUM	transcriptional regulator, lysR family
HF896_04550	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HF896_04555	ENOG4105CF1	Alkylated DNA repair protein
HF896_04560	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_04585	ENOG4108RH0	Crea protein
HF896_04600	ENOG4105BZ1	(ABC) transporter
HF896_04625	ENOG4105D7Q	type ii secretion system
HF896_04630	ENOG4105DEN	Luciferase family
HF896_04640	ENOG4107QHF	type ii secretion system protein e
HF896_04645	ENOG4105GVR	general secretion pathway protein D
HF896_04670	ENOG4108WWZ	General secretion pathway protein J
HF896_04685	ENOG4108VAU	general secretion pathway protein G
HF896_04700	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HF896_04705	ENOG4105C7B	Threonine dehydratase
HF896_04710	ENOG4108UKZ	OsmC family
HF896_04715	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
HF896_04720	ENOG4108Z9W	Outer membrane porin
HF896_04735	ENOG4105CH2	amidohydrolase
HF896_04740	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HF896_04745	ENOG4105C3U	ABC transporter
HF896_04750	ENOG4108JQ7	(ABC) transporter
HF896_04755	ENOG4108V1U	phospholipid-binding protein
HF896_04760	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HF896_04765	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HF896_04770	ENOG4107QP8	phosphohexose isomerase
HF896_04775	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HF896_04780	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HF896_04785	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HF896_04790	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HF896_04800	ENOG4105D1S	lipid A biosynthesis
HF896_04805	ENOG4105F04	LysR family Transcriptional regulator
HF896_04820	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HF896_04830	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HF896_04850	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HF896_04855	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HF896_04865	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HF896_04875	ENOG4105XQ6	frataxin-like protein
HF896_04880	ENOG4108JQC	penicillin-binding protein 1A
HF896_04905	ENOG4105E4G	Type IV pilus
HF896_04920	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HF896_04935	ENOG4105C26	Dehydrogenase
HF896_04965	ENOG4105EAB	amino acid AbC transporter
HF896_04970	ENOG4105E5Q	amino acid AbC transporter
HF896_04975	ENOG4105CDA	abc transporter atp-binding protein
HF896_04985	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HF896_04990	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HF896_04995	ENOG4105DHJ	ABC, transporter
HF896_05000	ENOG4105CY3	ABC transporter, permease
HF896_05005	ENOG4107PE3	Mammalian cell entry related domain protein
HF896_05030	ENOG4105DA5	(ABC) transporter
HF896_05035	ENOG4105E3A	(ABC) transporter
HF896_05040	ENOG4105VFK	BolA family
HF896_05045	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HF896_05050	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HF896_05070	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HF896_05075	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HF896_05085	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HF896_05100	ENOG4108I69	Glycosyl transferases group 1
HF896_05130	ENOG4105CMR	udp-glucose 4-epimerase
HF896_05135	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HF896_05140	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HF896_05145	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
HF896_05160	ENOG4107YU2	histidine triad (hIT) protein
HF896_05165	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HF896_05170	ENOG4107Z6S	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HF896_05175	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HF896_05180	ENOG4105C0H	protease
HF896_05185	ENOG4107QNR	UPF0135 protein
HF896_05190	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HF896_05195	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HF896_05200	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HF896_05205	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HF896_05210	ENOG4105EIX	cytochrome c1
HF896_05215	ENOG4107MKT	Stringent starvation protein a
HF896_05220	ENOG4105KB2	stringent starvation protein b
HF896_05235	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HF896_05250	ENOG4105M6F	mutator MutT protein
HF896_05255	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HF896_05260	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
HF896_05265	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HF896_05280	ENOG4107QHF	type ii secretion system protein e
HF896_05285	ENOG4108KU3	Integrase
HF896_05360	ENOG4105EAH	synthase
HF896_05365	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HF896_05370	ENOG4105K46	50S ribosomal protein l27
HF896_05375	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HF896_05380	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HF896_05385	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HF896_05390	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HF896_05395	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HF896_05400	ENOG4105C37	(CBS) domain
HF896_05405	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HF896_05415	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HF896_05420	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HF896_05425	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HF896_05435	ENOG4108MGI	Transcriptional regulator
HF896_05440	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HF896_05450	ENOG4105EGS	Mechanosensitive ion channel
HF896_05455	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
HF896_05460	ENOG4108IJ9	(ABC) transporter
HF896_05470	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HF896_05480	ENOG4108JQ1	Dehydrogenase
HF896_05500	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HF896_05515	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HF896_05535	ENOG4105C9M	aspartyl-trna synthetase
HF896_05550	ENOG4105DZQ	phospholipase D Transphosphatidylase
HF896_05555	ENOG4105EUJ	GTP cyclohydrolase i
HF896_05570	ENOG4105BZU	Histidine kinase
HF896_05575	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HF896_05580	ENOG4105NQN	cytochrome C
HF896_05595	ENOG410829K	Lysine exporter protein (Lyse ygga)
HF896_05600	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HF896_05610	ENOG4108JQ7	(ABC) transporter
HF896_05615	ENOG4105C3U	ABC transporter
HF896_05620	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HF896_05630	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HF896_05635	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HF896_05640	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HF896_05645	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HF896_05655	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HF896_05665	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
HF896_05670	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HF896_05680	ENOG4105CEN	a g-specific adenine glycosylase
HF896_05690	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HF896_05695	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HF896_05700	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HF896_05705	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HF896_05725	ENOG4105CSA	Coproporphyrinogen iii oxidase
HF896_05730	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HF896_05750	ENOG4105DSJ	YicC domain protein
HF896_05820	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
HF896_05850	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HF896_05855	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HF896_05860	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HF896_05865	ENOG4108RRZ	Transcription elongation factor GreB
HF896_05880	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HF896_05885	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HF896_05895	ENOG4105CP7	Triose-phosphate isomerase
HF896_05900	ENOG4107EJC	Preprotein translocase subunit SecG
HF896_05910	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HF896_05915	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HF896_05920	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HF896_05925	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HF896_05935	ENOG4107QIZ	NADH dehydrogenase
HF896_05940	ENOG4108IEH	NADH dehydrogenase subunit g
HF896_05945	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HF896_05950	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HF896_05955	ENOG4105DF2	NADH dehydrogenase subunit j
HF896_05960	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HF896_05970	ENOG4105C8S	subunit m
HF896_05975	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HF896_05995	ENOG4105D82	Glutamate dehydrogenase
HF896_06000	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HF896_06010	ENOG4105DQR	SNARE associated Golgi
HF896_06015	ENOG4107QUY	Guanine deaminase
HF896_06030	ENOG4105C7W	Xanthine dehydrogenase
HF896_06035	ENOG4108HR6	Dehydrogenase
HF896_06045	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HF896_06050	ENOG4105K8N	protein family UPF0079, ATPase
HF896_06055	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HF896_06075	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HF896_06080	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HF896_06090	ENOG4105D58	Diguanylate phosphodiesterase
HF896_06095	ENOG4105D58	Diguanylate phosphodiesterase
HF896_06100	ENOG4105ED9	Protein of unknown function (DUF455)
HF896_06105	ENOG4108Z0R	Transferase
HF896_06110	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HF896_06115	ENOG4105E89	ABC transporter
HF896_06120	ENOG4105DSP	amino acid AbC transporter
HF896_06130	ENOG4108JEH	abc transporter atp-binding protein
HF896_06135	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HF896_06140	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HF896_06150	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HF896_06155	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HF896_06160	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HF896_06170	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HF896_06175	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HF896_06180	ENOG4105EZE	Cupin 4 family protein
HF896_06195	ENOG4105GJM	(LipO)protein
HF896_06200	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HF896_06215	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HF896_06220	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HF896_06230	ENOG4108EC8	DNA internalization-related competence protein ComEC
HF896_06240	ENOG4105KHC	sulfurtransferase
HF896_06255	ENOG41086K9	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HF896_06265	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HF896_06270	ENOG4105CH5	extracellular solute-binding protein, family 7
HF896_06275	ENOG4107QRT	dEAD DEAH box helicase
HF896_06280	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HF896_06290	ENOG4105ECY	inositol monophosphatase
HF896_06300	ENOG4105D7W	serine acetyltransferase
HF896_06310	ENOG4105CPQ	Dehydrogenase
HF896_06315	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HF896_06320	ENOG4105N42	UPF0307 protein
HF896_06325	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HF896_06370	ENOG4106IJN	integrase catalytic domain-containing protein
HF896_06375	ENOG4105F5W	AtP-binding protein
HF896_06390	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HF896_06420	ENOG4105IJJ	transcriptional regulator, crp fnr family
HF896_06425	ENOG4105GIJ	Glycine betaine
HF896_06430	ENOG4108HQS	Glycine betaine
HF896_06435	ENOG4108IJ7	Glycine betaine
HF896_06445	ENOG4107QVM	von Willebrand factor, type A
HF896_06455	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HF896_06460	ENOG4105C0H	protease
HF896_06470	ENOG41080HT	Transcriptional regulator, arsr family
HF896_06480	ENOG4105EYA	deoxyribonuclease
HF896_06490	ENOG4105I7M	spermidine synthase
HF896_06495	ENOG4107QHF	type ii secretion system protein e
HF896_06510	ENOG4105CHR	reductase
HF896_06520	ENOG4105BZU	Histidine kinase
HF896_06525	ENOG4108IPJ	Membrane
HF896_06530	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HF896_06540	ENOG4108M0I	Transcriptional regulator
HF896_06545	ENOG4105DHU	Bile acid
HF896_06550	ENOG4105EAM	Na Pi-cotransporter
HF896_06555	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HF896_06560	ENOG4108IJ6	ABC transporter
HF896_06565	ENOG4108EG7	Binding-protein-dependent transport systems, inner membrane component
HF896_06570	ENOG4105E0C	molybdate abc transporter
HF896_06575	ENOG4107QKW	extracellular solute-binding protein family 1
HF896_06580	ENOG4105ETE	Transcriptional regulator (LacI family
HF896_06585	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HF896_06590	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HF896_06595	ENOG4105DTN	riboflavin biosynthesis protein ribF
HF896_06605	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_06610	ENOG4105X7H	acyl-CoA dehydrogenase
HF896_06615	ENOG4108YXG	UPF0502 protein
HF896_06620	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HF896_06630	ENOG4105W0E	50S ribosomal protein L33
HF896_06635	ENOG4105KDC	50s ribosomal protein l28
HF896_06640	ENOG4105C3M	thioredoxin reductase
HF896_06645	ENOG4105CNU	cell division protein FtsK
HF896_06650	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HF896_06655	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HF896_06660	ENOG4108RG0	uracil-dna glycosylase
HF896_06665	ENOG4105D1H	recombination factor protein RarA
HF896_06670	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_06675	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HF896_06680	ENOG4105C0Z	ABC transporter
HF896_06685	ENOG4108IV0	ABC, transporter
HF896_06700	ENOG4107GRR	phosphate transport regulator
HF896_06705	ENOG4107QXV	Phosphate transporter
HF896_06720	ENOG4105K5M	30s ribosomal protein S16
HF896_06725	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HF896_06730	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HF896_06735	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HF896_06740	ENOG4105P8F	nudix hydrolase
HF896_06745	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HF896_06750	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HF896_06755	ENOG4105CHH	sulfate transporter
HF896_06760	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HF896_06765	ENOG41090A4	Pterin carbinolamine dehydratase
HF896_06770	ENOG4105D0M	Protease HtpX homolog
HF896_06775	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HF896_06785	ENOG4105C1J	atp-dependent rna helicase
HF896_06790	ENOG4105BZU	Histidine kinase
HF896_06795	ENOG4105C2C	drug resistance transporter, Bcr CflA
HF896_06830	ENOG4108ETV	ABC transporter
HF896_06840	ENOG4105D05	Receptor
HF896_06875	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
HF896_06880	ENOG4105C4R	Atp-dependent dna helicase
HF896_06900	ENOG4105CUV	Homoserine Kinase
HF896_06915	ENOG4105C2M	dna polymerase I
HF896_06920	ENOG4105DUM	transcriptional regulator, lysR family
HF896_06925	ENOG4105CHR	reductase
HF896_06940	ENOG4105DND	Transcriptional regulator
HF896_06950	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_06955	ENOG4105E39	Enoyl-CoA hydratase
HF896_06960	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HF896_06970	ENOG4108NEV	two component transcriptional regulator, LytTR family
HF896_06975	ENOG4105EAC	phosphoserine phosphatase
HF896_06990	ENOG4108JA2	transcriptioN-repair coupling factor
HF896_06995	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
HF896_07000	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HF896_07005	ENOG4105E0F	Histidine kinase
HF896_07020	ENOG4105DTD	Dehydrogenase
HF896_07030	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HF896_07045	ENOG4105VFU	Rna-binding protein
HF896_07050	ENOG4108NVM	synthesis repressor PhaR
HF896_07055	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HF896_07060	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HF896_07070	ENOG4108KB2	LysR family Transcriptional regulator
HF896_07075	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HF896_07080	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_07090	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HF896_07110	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_07115	ENOG4107RZC	phospholipase d
HF896_07120	ENOG4105F4R	Transcriptional regulator mode
HF896_07130	ENOG4108JJB	ABC transporter
HF896_07145	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HF896_07150	ENOG4105E0C	molybdate abc transporter
HF896_07155	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HF896_07160	ENOG4105F4R	Transcriptional regulator mode
HF896_07165	ENOG4105C0Z	ABC transporter
HF896_07170	ENOG4108IV0	ABC, transporter
HF896_07185	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_07210	ENOG4105VN1	Heat shock protein
HF896_07215	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HF896_07220	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HF896_07230	ENOG4105C5I	Dehydrogenase
HF896_07235	ENOG4105K59	histidine triad (HIT) protein
HF896_07240	ENOG4108Z9W	Outer membrane porin
HF896_07250	ENOG4105BZU	Histidine kinase
HF896_07255	ENOG4105C2J	ABC transporter
HF896_07260	ENOG4105UIB	(ABC) transporter
HF896_07280	ENOG4105CJP	fad dependent oxidoreductase
HF896_07285	ENOG4105CDA	abc transporter atp-binding protein
HF896_07290	ENOG4105E5Q	amino acid AbC transporter
HF896_07295	ENOG4106TNF	Periplasmic binding protein
HF896_07310	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HF896_07320	ENOG4108J59	Extracellular solute-binding protein, family 5
HF896_07325	ENOG4108JQ7	(ABC) transporter
HF896_07330	ENOG4105C3U	ABC transporter
HF896_07335	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HF896_07340	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HF896_07350	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
HF896_07355	ENOG4105PI0	Ferredoxin
HF896_07365	ENOG4105CE1	Ferrous iron transport protein b
HF896_07375	ENOG4105PI0	Ferredoxin
HF896_07390	ENOG4105DBV	ornithine carbamoyltransferase
HF896_07395	ENOG4105C8Y	Acetylornithine aminotransferase
HF896_07415	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
HF896_07420	ENOG4105CJR	Integral membrane protein (MviN
HF896_07430	ENOG4105SHT	UspA domain-containing protein
HF896_07440	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HF896_07445	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HF896_07450	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HF896_07460	ENOG4105DJ0	Poly(A) Polymerase
HF896_07475	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HF896_07505	ENOG4105EGI	Transcriptional regulator
HF896_07540	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_07545	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_07550	ENOG4105ETT	transcriptional Regulator, LysR family
HF896_07590	ENOG4105C1J	atp-dependent rna helicase
HF896_07595	ENOG4105C5H	ABC transporter
HF896_07605	ENOG4105KXX	peptidase s58 dmpa
HF896_07635	ENOG4105W1Y	Transcriptional regulator
HF896_07660	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HF896_07675	ENOG4105CE9	30S ribosomal protein S2
HF896_07680	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HF896_07685	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HF896_07690	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HF896_07695	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HF896_07700	ENOG4105KNE	Phosphatidate cytidylyltransferase
HF896_07705	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HF896_07710	ENOG4105DZP	Membrane-associated zinc metalloprotease
HF896_07715	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HF896_07725	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HF896_07730	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HF896_07735	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HF896_07740	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HF896_07745	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HF896_07760	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HF896_07765	ENOG4105CD8	aminopeptidase N
HF896_07785	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
HF896_07795	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HF896_07800	ENOG4105CPC	Aldo Keto reductase
HF896_07805	ENOG4108Z66	YbaK ebsC protein
HF896_07810	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HF896_07820	ENOG4108WIW	Aspartyl protease
HF896_07825	ENOG4108VPT	UPF0234 protein
HF896_07830	ENOG4105D4A	Cell wall formation (By similarity)
HF896_07840	ENOG4105EX9	Membrane
HF896_07845	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HF896_07850	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
HF896_07855	ENOG4107TYC	hydantoinase B oxoprolinase
HF896_07860	ENOG4105HKX	acetone carboxylase, gamma subunit
HF896_07865	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HF896_07870	ENOG4105CDH	Citrulline--aspartate ligase
HF896_07875	ENOG4105NBK	UPF0345 protein
HF896_07885	ENOG4105KUZ	arsenate reductase
HF896_07890	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HF896_07900	ENOG4105E96	Colicin v production protein
HF896_07905	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HF896_07910	ENOG4105C28	cystathionine
HF896_07915	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HF896_08005	ENOG4105HMI	Membrane
HF896_08045	ENOG4105DUM	transcriptional regulator, lysR family
HF896_08060	ENOG4105DUM	transcriptional regulator, lysR family
HF896_08065	ENOG4105HMI	Membrane
HF896_08070	ENOG4105C26	Dehydrogenase
HF896_08075	ENOG4105EXG	Transcriptional regulator
HF896_08095	ENOG4105CN8	Transcriptional regulator
HF896_08105	ENOG4107RP9	extracellular solute-binding protein, family 3
HF896_08110	ENOG4105E5Q	amino acid AbC transporter
HF896_08115	ENOG4105DRP	amino acid AbC transporter
HF896_08120	ENOG4105F0I	Aminotransferase
HF896_08125	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HF896_08130	ENOG4105DFP	Integrase
HF896_08170	ENOG4107QKW	extracellular solute-binding protein family 1
HF896_08175	ENOG4108WFY	phasin family
HF896_08185	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HF896_08195	ENOG4105C5I	Dehydrogenase
HF896_08200	ENOG4105CGY	Dna recombination protein
HF896_08215	ENOG4107Z6W	Protein CrcB homolog
HF896_08230	ENOG4105W4C	monovalent cation H antiporter subunit F
HF896_08240	ENOG4107R4Z	monovalent cation h antiporter subunit d
HF896_08245	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HF896_08250	ENOG4105D65	subunit l
HF896_08260	ENOG4105CFV	Tetratricopeptide repeat protein
HF896_08270	ENOG4107TF3	peptidylprolyl cis-trans isomerase
HF896_08280	ENOG4107835	probably involved in intracellular septation (By similarity)
HF896_08285	ENOG4105E0X	reductase
HF896_08290	ENOG4105CNG	UPF0061 protein
HF896_08295	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_08305	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_08315	ENOG4105C0Z	ABC transporter
HF896_08320	ENOG4108IV0	ABC, transporter
HF896_08325	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HF896_08330	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_08340	ENOG4105DRP	amino acid AbC transporter
HF896_08345	ENOG4105DRP	amino acid AbC transporter
HF896_08350	ENOG4105CSU	acyl-Coa dehydrogenase
HF896_08375	ENOG4105DFG	type I secretion outer membrane protein
HF896_08385	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HF896_08390	ENOG4105YA8	Transcriptional regulator
HF896_08395	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HF896_08405	ENOG4105UGU	tonB-dependent Receptor
HF896_08425	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HF896_08450	ENOG4105BZM	domain protein
HF896_08480	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_08490	ENOG4105ETE	Transcriptional regulator (LacI family
HF896_08505	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HF896_08530	ENOG4105IKQ	hydratase
HF896_08550	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HF896_08560	ENOG4105DJ2	Major Facilitator Superfamily
HF896_08565	ENOG4107Y2X	deaminase
HF896_08570	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HF896_08575	ENOG4105HHA	aminodeoxychorismate lyase
HF896_08580	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HF896_08585	ENOG4107QRG	dna polymerase iii
HF896_08595	ENOG4105F8V	Hydrolase, tatD family
HF896_08615	ENOG4105DRR	Transcriptional regulator, GntR family
HF896_08625	ENOG4105E7W	lamb ycsf family protein
HF896_08630	ENOG4105CFM	UPF0317 protein
HF896_08635	ENOG4105P4J	Allophanate hydrolase, subunit 1
HF896_08640	ENOG4108JIK	carboxylase
HF896_08645	ENOG4105BZ1	(ABC) transporter
HF896_08650	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HF896_08655	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HF896_08660	ENOG4105UFD	tol-pal system protein YbgF
HF896_08665	ENOG4105CUZ	uba thif-type nad fad binding protein
HF896_08685	ENOG4105E9H	Lytic Murein transglycosylase
HF896_08690	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HF896_08695	ENOG4105D1A	Methyltransferase
HF896_08700	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HF896_08710	ENOG4105JSC	dimethylmenaquinone methyltransferase
HF896_08715	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HF896_08720	ENOG4105CN8	Transcriptional regulator
HF896_08725	ENOG4107RP9	extracellular solute-binding protein, family 3
HF896_08750	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HF896_08760	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HF896_08765	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HF896_08780	ENOG4105C26	Dehydrogenase
HF896_08790	ENOG4105F0N	pyrophosphate phospho-hydrolase
HF896_08795	ENOG4108V3W	Chemotaxis protein, CheW
HF896_08800	ENOG4105C8Q	Methyl-accepting chemotaxis
HF896_08820	ENOG4108YZA	Nitrogen regulatory protein pii
HF896_08825	ENOG4108URH	decarboxylase
HF896_08830	ENOG41080IJ	Diacylglycerol kinase
HF896_08850	ENOG4105JVQ	RNA Polymerase
HF896_08855	ENOG4105C7K	acetolactate synthase
HF896_08860	ENOG4108ZP8	Acetolactate synthase small subunit
HF896_08865	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HF896_08870	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HF896_08875	ENOG4108RXX	maleylacetoacetate isomerase
HF896_08885	ENOG4105D2S	major facilitator superfamily
HF896_08895	ENOG4108M0I	Transcriptional regulator
HF896_08900	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HF896_08905	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HF896_08910	ENOG41061WM	D-Alanyl-D-Alanine
HF896_08915	ENOG41069M3	Transcriptional regulator
HF896_08920	ENOG4105CK7	Sodium proline symporter
HF896_08925	ENOG4105C26	Dehydrogenase
HF896_08930	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_08945	ENOG4108UKI	Enoyl-CoA hydratase
HF896_08950	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HF896_08960	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HF896_08965	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HF896_08995	ENOG4105CAY	ferredoxin--nadp reductase
HF896_09000	ENOG4108Z4U	Ferredoxin
HF896_09010	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HF896_09015	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HF896_09030	ENOG4107TSN	permease
HF896_09035	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HF896_09040	ENOG4105EN6	Membrane
HF896_09045	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HF896_09050	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HF896_09070	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_09075	ENOG4105CHR	reductase
HF896_09085	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_09095	ENOG4105C0Z	ABC transporter
HF896_09100	ENOG4108IV0	ABC, transporter
HF896_09110	ENOG4105J5T	Amp-dependent synthetase and ligase
HF896_09115	ENOG4105CHR	reductase
HF896_09160	ENOG41088T4	Helicase IV
HF896_09170	ENOG4105F5W	AtP-binding protein
HF896_09175	ENOG4106IJN	integrase catalytic domain-containing protein
HF896_09185	ENOG41088T4	Helicase IV
HF896_09195	ENOG4105D5G	Transposase
HF896_09230	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HF896_09250	ENOG4108NF7	phage-type endonuclease
HF896_09285	ENOG4108P8R	
HF896_09315	ENOG4105D85	methylase
HF896_09345	ENOG4105C7K	acetolactate synthase
HF896_09350	ENOG4105ETT	transcriptional Regulator, LysR family
HF896_09365	ENOG4105CXN	decarboxylase
HF896_09370	ENOG4108ZCF	integral membrane protein
HF896_09380	ENOG4105Z2P	Protein of unknown function (DUF465)
HF896_09390	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HF896_09405	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HF896_09410	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HF896_09415	ENOG4108JQ5	ABC transporter
HF896_09425	ENOG4105DUM	transcriptional regulator, lysR family
HF896_09445	ENOG4105IPI	Membrane
HF896_09450	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HF896_09455	ENOG4105C7S	Dehydrogenase
HF896_09460	ENOG4107QN2	dihydrolipoyl dehydrogenase
HF896_09465	ENOG4105D6Z	AFG1 family ATPase
HF896_09475	ENOG4108ZF3	Phosphatase
HF896_09480	ENOG4105DVT	helicase
HF896_09490	ENOG4105C0B	DNA polymerase III (alpha subunit)
HF896_09495	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HF896_09500	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HF896_09505	ENOG4107P2S	Transcriptional regulator
HF896_09510	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HF896_09515	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
HF896_09520	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HF896_09525	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HF896_09530	ENOG4105C01	Dihydroxy-acid dehydratase
HF896_09535	ENOG4108UHU	Aldolase
HF896_09550	ENOG410626B	catechol 1,2-dioxygenase
HF896_09555	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
HF896_09560	ENOG4105F2Z	3-oxoadipate enol-lactonase
HF896_09575	ENOG4105D2S	major facilitator superfamily
HF896_09580	ENOG4108MR5	
HF896_09585	ENOG4108MZY	
HF896_09590	ENOG4108UYE	Lactoylglutathione lyase
HF896_09610	ENOG4108JJB	ABC transporter
HF896_09620	ENOG4107ZYJ	bioY protein
HF896_09625	ENOG4107F3J	Amp-dependent synthetase and ligase
HF896_09630	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_09635	ENOG4105CQ7	ATP-dependent helicase
HF896_09645	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HF896_09650	ENOG4105HDK	L-asparaginase
HF896_09655	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HF896_09660	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HF896_09665	ENOG4105W49	UPF0434 protein
HF896_09670	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HF896_09675	ENOG4105M8F	Biopolymer transport protein exbD tolR
HF896_09685	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HF896_09690	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HF896_09695	ENOG4105E9K	Isocitrate dehydrogenase
HF896_09735	ENOG4105WD1	Membrane
HF896_09740	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HF896_09745	ENOG4105C2W	permease
HF896_09755	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HF896_09760	ENOG4108ETH	Formylglycinamide ribotide synthetase
HF896_09765	ENOG4105CKW	Inner membrane protein yedI
HF896_09775	ENOG41067HS	methyltransferase
HF896_09790	ENOG4105CFP	Peptidase U32
HF896_09800	ENOG4108Z6B	deaminase
HF896_09805	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HF896_09840	ENOG4105DH8	myo-inositol catabolism
HF896_09855	ENOG4107QKV	phosphomannomutase
HF896_09860	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HF896_09865	ENOG4105CD5	CoA-binding domain protein
HF896_09870	ENOG4105D3G	Pseudouridine synthase
HF896_09875	ENOG4108WYP	Transcriptional regulator
HF896_09880	ENOG4105DG4	malate L-lactate dehydrogenase
HF896_09885	ENOG41062YB	Trap dicarboxylate transporter, dctp subunit
HF896_09890	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HF896_09900	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HF896_09905	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HF896_09910	ENOG4105BZU	Histidine kinase
HF896_09915	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HF896_09920	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HF896_09925	ENOG4105CVN	desaturase
HF896_09930	ENOG4105EQ1	Transcriptional regulator
HF896_09940	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HF896_09945	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HF896_09950	ENOG4105C26	Dehydrogenase
HF896_09955	ENOG4105EQX	glucarate dehydratase
HF896_09960	ENOG4105C5I	Dehydrogenase
HF896_09970	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
HF896_09985	ENOG4105EQX	glucarate dehydratase
HF896_09995	ENOG4105CTX	dehydratase
HF896_10005	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HF896_10025	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HF896_10035	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_10045	ENOG4105C26	Dehydrogenase
HF896_10050	ENOG4106NZI	LysR family Transcriptional regulator
HF896_10055	ENOG4105D8V	Glucose sorbosone dehydrogenase
HF896_10065	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HF896_10075	ENOG4105BZU	Histidine kinase
HF896_10090	ENOG4105C28	cystathionine
HF896_10100	ENOG4108UJV	acyl-CoA thioesterase i
HF896_10105	ENOG4108I0Y	(ABC) transporter
HF896_10110	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
HF896_10115	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HF896_10150	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
HF896_10160	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HF896_10175	ENOG410814C	multidrug resistance protein
HF896_10195	ENOG4108MN8	Membrane
HF896_10200	ENOG4108ZJF	Glcg protein
HF896_10210	ENOG4105SG9	biopolymer transport protein, ExbD
HF896_10240	ENOG4108I9X	Isocitrate lyase
HF896_10250	ENOG4105C22	threonyL-tRNA synthetase
HF896_10255	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HF896_10260	ENOG4105VJV	50s ribosomal protein L35
HF896_10265	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HF896_10270	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HF896_10275	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HF896_10280	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HF896_10285	ENOG4108XDN	Transcriptional regulator
HF896_10300	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HF896_10305	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HF896_10320	ENOG4105HBR	Rna-binding protein
HF896_10325	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HF896_10330	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HF896_10340	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HF896_10345	ENOG4105BZU	Histidine kinase
HF896_10365	ENOG4105C9X	ppx gppa phosphatase
HF896_10370	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HF896_10375	ENOG4105C8U	phosphate abc transporter
HF896_10380	ENOG4105E2Z	phosphate ABC transporter (Permease
HF896_10385	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HF896_10390	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HF896_10395	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HF896_10400	ENOG4105BZU	Histidine kinase
HF896_10405	ENOG4107QI1	Mate efflux family protein
HF896_10415	ENOG4105NRA	50s ribosomal protein l31 type b
HF896_10420	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HF896_10425	ENOG4105K63	Thioredoxin
HF896_10430	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HF896_10440	ENOG4105EUB	pirin domain protein
HF896_10445	ENOG4105EUB	pirin domain protein
HF896_10460	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HF896_10470	ENOG4105S10	periplasmic binding protein
HF896_10475	ENOG4108I9K	permease protein
HF896_10480	ENOG4105E0A	ABC, transporter
HF896_10495	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HF896_10500	ENOG4105E0C	molybdate abc transporter
HF896_10505	ENOG4107XWS	modD protein
HF896_10510	ENOG4105F4R	Transcriptional regulator mode
HF896_10520	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HF896_10525	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HF896_10530	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HF896_10540	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HF896_10545	ENOG4108UMI	ABC transporter, permease
HF896_10550	ENOG4105D01	(LipO)protein
HF896_10560	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HF896_10575	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HF896_10580	ENOG4108I5D	sulfate abc transporter
HF896_10590	ENOG4108IJ6	ABC transporter
HF896_10595	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HF896_10600	ENOG4105DHT	Metal Dependent Phosphohydrolase
HF896_10605	ENOG41073TP	transcriptional regulator
HF896_10615	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HF896_10620	ENOG41083Z3	extracellular ligand-binding receptor
HF896_10625	ENOG4108IV0	ABC, transporter
HF896_10630	ENOG4105C0Z	ABC transporter
HF896_10640	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_10655	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HF896_10665	ENOG4108EKC	n-acetylglutamate synthase
HF896_10670	ENOG4105EXC	Acyl-transferase
HF896_10690	ENOG4108ESY	Metal dependent phosphohydrolase
HF896_10700	ENOG4105VCC	30S ribosomal protein S21
HF896_10710	ENOG4105C3K	feS assembly ATPase SufC
HF896_10720	ENOG4105C9B	Cysteine desulfurase
HF896_10725	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HF896_10745	ENOG4105CBX	hi0933 family
HF896_10750	ENOG4108S4H	thioesterase Superfamily protein
HF896_10755	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HF896_10760	ENOG4107S1N	anthranilate phosphoribosyltransferase
HF896_10785	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HF896_10790	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HF896_10795	ENOG4105BZS	acriflavin resistance protein
HF896_10800	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HF896_10815	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HF896_10825	ENOG410624X	efflux transporter, rnd family, mfp subunit
HF896_10830	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HF896_10835	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HF896_10845	ENOG4105ES9	amino acid
HF896_10850	ENOG4105HMI	Membrane
HF896_10855	ENOG4105DUM	transcriptional regulator, lysR family
HF896_10860	ENOG4105C5I	Dehydrogenase
HF896_10865	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HF896_10870	ENOG4108PZW	LysR family Transcriptional regulator
HF896_10905	ENOG4105CVE	Lytic murein transglycosylase
HF896_10910	ENOG4105F8C	transglutaminase domain-containing protein
HF896_10920	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HF896_10935	ENOG4105BZJ	Electron transfer flavoprotein
HF896_10940	ENOG4105C10	Electron transfer flavoprotein
HF896_10945	ENOG4105CSU	acyl-Coa dehydrogenase
HF896_10960	ENOG4105NXH	GreA GreB family elongation factor
HF896_10995	ENOG4105C4W	S-formylglutathione hydrolase
HF896_11010	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HF896_11015	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HF896_11020	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HF896_11030	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HF896_11040	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HF896_11045	ENOG4105EW9	transcriptional regulator AsnC family
HF896_11050	ENOG4107RUY	(E1 component), alpha subunit
HF896_11055	ENOG4105CPP	Dehydrogenase, E1 component
HF896_11065	ENOG4107QKR	Dehydrogenase
HF896_11070	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
HF896_11085	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
HF896_11090	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HF896_11100	ENOG4105C7J	ABC transporter, permease
HF896_11110	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HF896_11120	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_11130	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_11135	ENOG410846T	CoA-transferase family III
HF896_11140	ENOG4105DQ4	alcohol dehydrogenase
HF896_11150	ENOG4105E39	Enoyl-CoA hydratase
HF896_11155	ENOG4105DHQ	Histidine kinase
HF896_11160	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HF896_11170	ENOG4105DIJ	Phosphoethanolamine transferase
HF896_11195	ENOG4108R85	Short chain dehydrogenase
HF896_11200	ENOG4105ETE	Transcriptional regulator (LacI family
HF896_11250	ENOG4105DZR	Type I site-specific deoxyribonuclease
HF896_11265	ENOG41082EK	Restriction modification system DNA (Specificity
HF896_11270	ENOG4105CVR	type I restriction-modification system
HF896_11305	ENOG4105KTU	Transcriptional regulator, arsr family
HF896_11315	ENOG4105BZS	acriflavin resistance protein
HF896_11320	ENOG4105DFG	type I secretion outer membrane protein
HF896_11325	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
HF896_11340	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HF896_11355	ENOG4105DHQ	Histidine kinase
HF896_11370	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HF896_11385	ENOG4107QX3	carboxylase
HF896_11390	ENOG4105DJT	lAO AO transport system ATPase
HF896_11405	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_11415	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HF896_11420	ENOG4105DRR	Transcriptional regulator, GntR family
HF896_11425	ENOG4108IQE	Amp-dependent synthetase and ligase
HF896_11445	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HF896_11460	ENOG4108R3D	Electron transport complex
HF896_11470	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HF896_11475	ENOG4105CZX	twitching motility protein
HF896_11480	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HF896_11485	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HF896_11490	ENOG4106P55	Transcriptional regulator
HF896_11495	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_11500	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_11510	ENOG4105C5H	ABC transporter
HF896_11515	ENOG4105CHR	reductase
HF896_11520	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_11525	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HF896_11535	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HF896_11560	ENOG4108JQC	penicillin-binding protein 1A
HF896_11565	ENOG4105D78	K07001 NTE family protein
HF896_11570	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HF896_11580	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HF896_11590	ENOG4105KK4	UPF0060 membrane protein
HF896_11595	ENOG4105BZU	Histidine kinase
HF896_11600	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HF896_11610	ENOG4105K4H	Nlp p60 protein
HF896_11625	ENOG4108C33	Resolvase
HF896_11670	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HF896_11690	ENOG4108PGP	mmge prpd family protein
HF896_11695	ENOG4105JSC	dimethylmenaquinone methyltransferase
HF896_11700	ENOG4105ETT	transcriptional Regulator, LysR family
HF896_11725	ENOG4107QN2	dihydrolipoyl dehydrogenase
HF896_11730	ENOG4107QSN	dihydrolipoamide acetyltransferase
HF896_11735	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HF896_11740	ENOG4105BZU	Histidine kinase
HF896_11745	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HF896_11750	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HF896_11755	ENOG4105DGW	oligopeptidase A
HF896_11765	ENOG4105E66	phosphoriboisomerase A
HF896_11770	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HF896_11790	ENOG4105D5U	fad dependent oxidoreductase
HF896_11805	ENOG4107RZZ	dna polymerase iii epsilon subunit
HF896_11810	ENOG4108ZIT	Ferredoxin, 2FE-2S
HF896_11815	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HF896_11830	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HF896_11835	ENOG4105C3J	Cysteine desulfurase
HF896_11840	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HF896_11850	ENOG4105CGF	Aromatic amino acid aminotransferase
HF896_11855	ENOG4105CCT	upf0313 protein
HF896_11860	ENOG41090JD	Blue (Type 1) copper domain protein
HF896_11865	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HF896_11870	ENOG4105BZC	d-serine deaminase
HF896_11875	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HF896_11885	ENOG4105EMN	RNA polymerase sigma factor
HF896_11910	ENOG4107QX9	Thiol disulfide interChange protein
HF896_11925	ENOG4105WH1	Two component transcriptional regulator luxr family
HF896_11930	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HF896_11940	ENOG4105D3G	Pseudouridine synthase
HF896_11945	ENOG410904N	short-chain dehydrogenase reductase
HF896_11950	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_11965	ENOG4107YZX	Universal stress protein
HF896_12010	ENOG4105C5I	Dehydrogenase
HF896_12030	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HF896_12050	ENOG4107R11	Transcriptional regulator
HF896_12055	ENOG4105CHM	Aminotransferase
HF896_12070	ENOG4105C03	ribonuclease
HF896_12075	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HF896_12080	ENOG4105F64	nitrite reductase
HF896_12100	ENOG4108UMR	transcriptional regulator AsnC family
HF896_12120	ENOG4108Z03	MAF-like protein
HF896_12125	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HF896_12130	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HF896_12135	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HF896_12140	ENOG4105C12	Phosphoribosylglycinamide synthetase
HF896_12145	ENOG4105CDY	transcriptional regulatory protein
HF896_12150	ENOG4105D7A	ATP-binding protein
HF896_12155	ENOG4105CYM	Glutathione S-transferase
HF896_12160	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HF896_12170	ENOG41067MG	lrgb family
HF896_12190	ENOG4106IJN	integrase catalytic domain-containing protein
HF896_12195	ENOG4105F5W	AtP-binding protein
HF896_12205	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HF896_12260	ENOG4105CDY	transcriptional regulatory protein
HF896_12270	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HF896_12275	ENOG4108YYQ	gCN5-related N-acetyltransferase
HF896_12280	ENOG4105DSF	transport protein
HF896_12285	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HF896_12290	ENOG4105CJB	Exodeoxyribonuclease I
HF896_12295	ENOG4105CVE	Lytic murein transglycosylase
HF896_12300	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HF896_12315	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HF896_12325	ENOG4105CMQ	Chloride channel
HF896_12330	ENOG4105CFH	Aspartokinase
HF896_12335	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HF896_12350	ENOG4105C8N	cysteinyl-tRNA synthetase
HF896_12375	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HF896_12380	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
HF896_12385	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HF896_12390	ENOG4105FB2	class II Aldolase
HF896_12395	ENOG4105G63	Type III effector Hrp-dependent
HF896_12400	ENOG4105EXW	epimerase dehydratase
HF896_12405	ENOG4105ZXK	Dehydrogenase
HF896_12410	ENOG4105CSP	Major Facilitator Superfamily
HF896_12420	ENOG4105JXH	GntR family transcriptional regulator
HF896_12425	ENOG4107RSM	transcriptional regulator
HF896_12435	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HF896_12440	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HF896_12445	ENOG4108YXU	transcriptional regulator AsnC family
HF896_12460	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HF896_12465	ENOG4108YZN	class I peptide chain release factor
HF896_12475	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HF896_12485	ENOG4105CX6	glutaminyL-tRNA synthetase
HF896_12500	ENOG4108IJ0	Aspartate ammonia-lyase
HF896_12510	ENOG4108R99	pseudouridine synthase
HF896_12515	ENOG4105DTR	rard protein
HF896_12540	ENOG4105DR9	pseudouridine synthase
HF896_12550	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HF896_12580	ENOG4105M4H	endoribonuclease L-psp
HF896_12595	ENOG4105D9M	gamma-glutamylcysteine synthetase
HF896_12600	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HF896_12615	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HF896_12620	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HF896_12625	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HF896_12630	ENOG4105CHM	Aminotransferase
HF896_12635	ENOG4107YD3	Thioesterase
HF896_12640	ENOG4105E02	MotA TolQ exbB proton channel
HF896_12645	ENOG4105M8F	Biopolymer transport protein exbD tolR
HF896_12655	ENOG4105CSH	Transporter
HF896_12660	ENOG4105E2S	oxidase) subunit II
HF896_12665	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HF896_12670	ENOG4105CCU	oxidase (Subunit III)
HF896_12675	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HF896_12685	ENOG4105TX3	Histidine kinase
HF896_12690	ENOG4108UYB	regulatoR
HF896_12710	ENOG4105CFP	Peptidase U32
HF896_12715	ENOG4105CKK	Glycosyl transferase, family 2
HF896_12745	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HF896_12760	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HF896_12780	ENOG4105DC8	reductase
HF896_12785	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_12795	ENOG4105CSU	acyl-Coa dehydrogenase
HF896_12800	ENOG4107RSM	transcriptional regulator
HF896_12810	ENOG4107QIJ	Aconitate hydratase 2
HF896_12825	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HF896_12830	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HF896_12835	ENOG4105FDP	GntR family transcriptional regulator
HF896_12840	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HF896_12845	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HF896_12855	ENOG4105E33	succinate dehydrogenase
HF896_12860	ENOG41060IS	Flavinator of succinate dehydrogenase
HF896_12865	ENOG4105BZN	citrate synthase
HF896_12910	ENOG4105F5W	AtP-binding protein
HF896_12915	ENOG4106IJN	integrase catalytic domain-containing protein
HF896_12965	ENOG4105DFP	Integrase
HF896_12970	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HF896_12975	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HF896_12990	ENOG4108Z1B	Cyclase dehydrase
HF896_12995	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HF896_13015	ENOG4105E39	Enoyl-CoA hydratase
HF896_13025	ENOG4105CI3	gtp-binding protein typa
HF896_13030	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HF896_13035	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HF896_13040	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HF896_13045	ENOG4105CHV	Transcription elongation factor NusA
HF896_13050	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HF896_13055	ENOG4105K63	Thioredoxin
HF896_13060	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HF896_13070	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HF896_13075	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HF896_13100	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HF896_13105	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HF896_13110	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HF896_13115	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HF896_13140	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
HF896_13145	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HF896_13170	ENOG4106BE1	Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers (By similarity)
HF896_13195	ENOG4105DHQ	Histidine kinase
HF896_13200	ENOG4105VEJ	Heat shock protein
HF896_13210	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
HF896_13220	ENOG4105CFF	transcriptional regulator
HF896_13230	ENOG4105BZN	citrate synthase
HF896_13235	ENOG4108I0Z	Aconitate hydratase
HF896_13240	ENOG4105C7F	AcnD-accessory protein PrpF
HF896_13265	ENOG4105DZ2	Transcriptional regulator
HF896_13270	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HF896_13280	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HF896_13285	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HF896_13300	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HF896_13310	ENOG4105CHR	reductase
HF896_13325	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HF896_13330	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HF896_13335	ENOG4105UYK	outer membrane protein a
HF896_13340	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HF896_13345	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HF896_13360	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HF896_13365	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HF896_13370	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HF896_13380	ENOG4105BZU	Histidine kinase
HF896_13390	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HF896_13395	ENOG4108IJ8	ABC transporter
HF896_13400	ENOG4105DJ4	phosphatidylserine decarboxylase
HF896_13415	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HF896_13450	ENOG4105EJC	lysr family transcriptional regulator
HF896_13455	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HF896_13460	ENOG4105D78	K07001 NTE family protein
HF896_13475	ENOG4105CTX	dehydratase
HF896_13480	ENOG4105C26	Dehydrogenase
HF896_13485	ENOG4105CNV	Aldolase
HF896_13495	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HF896_13510	ENOG4105CI2	imidazolone-5-propionate hydrolase
HF896_13515	ENOG41090B9	response to stress
HF896_13520	ENOG4105CDA	abc transporter atp-binding protein
HF896_13525	ENOG4105E5Q	amino acid AbC transporter
HF896_13530	ENOG4105EAB	amino acid AbC transporter
HF896_13540	ENOG4105CGP	Urocanate hydratase
HF896_13545	ENOG4105ETS	cytosine purines uracil thiamine allantoin
HF896_13550	ENOG4105CZE	histidine utilization repressor
HF896_13555	ENOG4105C84	Histidine ammonia-lyase
HF896_13560	ENOG4105CZE	histidine utilization repressor
HF896_13570	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HF896_13590	ENOG4105C5Q	Transcriptional regulator
HF896_13605	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HF896_13610	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_13615	ENOG4105SKE	transcriptional Regulator LysR family
HF896_13625	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HF896_13635	ENOG4107QN1	sodium solute
HF896_13650	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HF896_13680	ENOG4105CH6	catalase
HF896_13685	ENOG4108JU3	Alkyl hydroperoxide reductase
HF896_13695	ENOG4108UQY	Iron-storage protein
HF896_13700	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
HF896_13705	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
HF896_13710	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HF896_13715	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HF896_13735	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HF896_13760	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HF896_13765	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HF896_13770	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HF896_13775	ENOG4105E09	nadh pyrophosphatase
HF896_13780	ENOG4105C6T	cysteine synthase
HF896_13785	ENOG4108VKG	metal-dependent hydrolase
HF896_13810	ENOG4105D70	Integrase catalytic subunit
HF896_13815	ENOG4105F5W	AtP-binding protein
HF896_13825	ENOG4107RP9	extracellular solute-binding protein, family 3
HF896_13855	ENOG4107QX3	carboxylase
HF896_13865	ENOG4107HP6	Transcriptional regulator
HF896_13875	ENOG4105E39	Enoyl-CoA hydratase
HF896_13895	ENOG4108Z7G	MaoC domain protein dehydratase
HF896_13900	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_13905	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_13920	ENOG4105CYC	Transferase
HF896_13925	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_13940	ENOG4105EA8	2-Nitropropane dioxygenase
HF896_13945	ENOG4105E39	Enoyl-CoA hydratase
HF896_13950	ENOG4105C10	Electron transfer flavoprotein
HF896_13955	ENOG4105BZJ	Electron transfer flavoprotein
HF896_13995	ENOG4105CC9	acyl-Coa dehydrogenase
HF896_14000	ENOG4105UPE	Enoyl-CoA hydratase
HF896_14010	ENOG4105CD5	CoA-binding domain protein
HF896_14015	ENOG4105CHR	reductase
HF896_14020	ENOG4107258	Transcriptional regulator
HF896_14035	ENOG4105CC9	acyl-Coa dehydrogenase
HF896_14040	ENOG4108KC2	acyl-Coa dehydrogenase
HF896_14090	ENOG4105F5W	AtP-binding protein
HF896_14095	ENOG4106IJN	integrase catalytic domain-containing protein
HF896_14110	ENOG4106NZI	LysR family Transcriptional regulator
HF896_14125	ENOG41081QV	Universal stress protein
HF896_14130	ENOG4105CHR	reductase
HF896_14140	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HF896_14145	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HF896_14155	ENOG4105D0S	secretion protein (HlyD
HF896_14160	ENOG4105CJ1	ABC, transporter
HF896_14165	ENOG4107QWP	ABC-2 type transporter
HF896_14170	ENOG4107QWP	ABC-2 type transporter
HF896_14180	ENOG4105C0A	alcohol dehydrogenase
HF896_14190	ENOG4105CY0	Metallo-Beta-Lactamase
HF896_14195	ENOG4105EWT	decarboxylase family
HF896_14215	ENOG4107QRI	Phosphoketolase
HF896_14240	ENOG4105EMN	RNA polymerase sigma factor
HF896_14260	ENOG4105CJ2	(LipO)protein
HF896_14270	ENOG4105CPW	cytochrome b561
HF896_14275	ENOG4108W63	CRP FNR family transcriptional regulator
HF896_14310	ENOG4107QJE	Chromosome Partitioning Protein
HF896_14355	ENOG4105VUN	Transcriptional regulator
HF896_14365	ENOG4105D5G	Transposase
HF896_14435	ENOG4105VUH	addiction module killer protein
HF896_14450	ENOG4105E39	Enoyl-CoA hydratase
HF896_14465	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HF896_14475	ENOG4107QX3	carboxylase
HF896_14480	ENOG4105DZS	Phenylacetate-CoA ligase
HF896_14485	ENOG4105E39	Enoyl-CoA hydratase
HF896_14495	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HF896_14520	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HF896_14560	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_14565	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_14575	ENOG4108IV0	ABC, transporter
HF896_14580	ENOG4105C0Z	ABC transporter
HF896_14585	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HF896_14590	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_14600	ENOG4108Z9W	Outer membrane porin
HF896_14610	ENOG4105E39	Enoyl-CoA hydratase
HF896_14615	ENOG4105C26	Dehydrogenase
HF896_14620	ENOG4105C26	Dehydrogenase
HF896_14640	ENOG4105C26	Dehydrogenase
HF896_14645	ENOG4105CPQ	Dehydrogenase
HF896_14655	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_14660	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HF896_14665	ENOG4105C0Z	ABC transporter
HF896_14670	ENOG4108IV0	ABC, transporter
HF896_14675	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HF896_14680	ENOG4105CI0	Citrate lyase
HF896_14690	ENOG4108M9J	MaoC like domain protein
HF896_14695	ENOG4105C10	Electron transfer flavoprotein
HF896_14700	ENOG4105BZJ	Electron transfer flavoprotein
HF896_14705	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_14710	ENOG4105DND	Transcriptional regulator
HF896_14720	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_14730	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HF896_14735	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_14740	ENOG4105CHR	reductase
HF896_14750	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_14800	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_14810	ENOG4105E39	Enoyl-CoA hydratase
HF896_14815	ENOG4105DTD	Dehydrogenase
HF896_14820	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_14840	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_14845	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HF896_14855	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_14860	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HF896_14870	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_14895	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HF896_14900	ENOG4108IV0	ABC, transporter
HF896_14905	ENOG4105C0Z	ABC transporter
HF896_14915	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_14930	ENOG4108TKH	Nitroreductase
HF896_14945	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_14950	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_14960	ENOG4105DJG	MaoC domain protein dehydratase
HF896_14965	ENOG4105CI0	Citrate lyase
HF896_14970	ENOG4108RZE	Tetr family transcriptional regulator
HF896_14985	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HF896_14990	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HF896_14995	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HF896_15000	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HF896_15010	ENOG4105BZS	acriflavin resistance protein
HF896_15025	ENOG4105FE1	phytoene synthase
HF896_15030	ENOG4105C8Q	Methyl-accepting chemotaxis
HF896_15035	ENOG4107VFM	Dehydrogenase
HF896_15045	ENOG4107S2Z	UPF0761 membrane protein
HF896_15055	ENOG4105CQB	FAD linked oxidase domain protein
HF896_15060	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HF896_15075	ENOG4105ER2	Ompa motb domain protein
HF896_15095	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HF896_15100	ENOG4105C08	Histidine kinase
HF896_15110	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HF896_15115	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HF896_15125	ENOG4105CGK	Exodeoxyribonuclease III
HF896_15130	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HF896_15135	ENOG4105CUX	Signal transduction histidine kinase
HF896_15175	ENOG4105I08	Pseudouridine synthase
HF896_15210	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HF896_15215	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HF896_15225	ENOG4105EPW	hflc protein
HF896_15230	ENOG4107QJR	hflk protein
HF896_15235	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HF896_15240	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HF896_15245	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HF896_15250	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HF896_15260	ENOG4105CUT	histidyl-tRNA synthetase
HF896_15265	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HF896_15280	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HF896_15285	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HF896_15290	ENOG4105FE9	pseudouridine synthase
HF896_15295	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HF896_15300	ENOG4105C34	Pseudouridine synthase
HF896_15305	ENOG4108K5P	(LipO)protein
HF896_15310	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HF896_15315	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HF896_15325	ENOG4105DGI	Alkaline phosphatase
HF896_15390	ENOG4105BZU	Histidine kinase
HF896_15395	ENOG4105NI8	Cytosine-specific methyltransferase
HF896_15475	ENOG4106NZI	LysR family Transcriptional regulator
HF896_15535	ENOG4107QJE	Chromosome Partitioning Protein
HF896_15580	ENOG4105FA0	parb-like partition protein
HF896_15620	ENOG4107R08	Integrase
HF896_15625	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HF896_15630	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HF896_15640	ENOG4105BZS	acriflavin resistance protein
HF896_15655	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HF896_15670	ENOG4105C2F	Histidine kinase
HF896_15675	ENOG4108VAC	response regulator
HF896_15680	ENOG4105DXI	Major Facilitator superfamily
HF896_15690	ENOG4105MSY	salicylate hydroxylase
HF896_15695	ENOG4107QM5	aconitate hydratase
HF896_15700	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS
HF896_15705	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HF896_15715	ENOG4105MPD	Cytochrome
HF896_15730	ENOG4105HEE	Binding Domain protein
HF896_15735	ENOG4105DH4	Periplasmic copper-binding protein
HF896_15740	ENOG4105CIG	ABC transporter
HF896_15745	ENOG4108T0W	nitrous oxide maturation protein NosY
HF896_15760	ENOG4105C1J	atp-dependent rna helicase
HF896_15765	ENOG4105CGZ	zinc metallopeptidase
HF896_15770	ENOG4105DHP	deoxycytidine triphosphate deaminase
HF896_15790	ENOG4105VT2	5-hydroxyisourate hydrolase
HF896_15795	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HF896_15810	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HF896_15815	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HF896_15820	ENOG41060W2	glyoxylate carboligase
HF896_15825	ENOG4105CC0	LysR family Transcriptional regulator
HF896_15830	ENOG4107RP9	extracellular solute-binding protein, family 3
HF896_15860	ENOG4105EJC	lysr family transcriptional regulator
HF896_15865	ENOG4107YCY	Transcriptional regulator
HF896_15880	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HF896_15885	ENOG4105BZU	Histidine kinase
HF896_15895	ENOG4105C8Q	Methyl-accepting chemotaxis
HF896_15900	ENOG4105C2W	permease
HF896_15905	ENOG4105C6K	Malic enzyme
HF896_15930	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HF896_15935	ENOG4108IAB	Phoh family
HF896_15940	ENOG4105C26	Dehydrogenase
HF896_15945	ENOG4105CDU	Replicative dna helicase
HF896_15950	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HF896_15955	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HF896_15965	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HF896_15970	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HF896_15975	ENOG4105CFG	Acts as a chaperone (By similarity)
HF896_15980	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HF896_15990	ENOG4105C0F	tryptophanase EC 4.1.99.1
HF896_16015	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HF896_16020	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HF896_16030	ENOG4105CY0	Metallo-Beta-Lactamase
HF896_16040	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HF896_16045	ENOG4106BSU	Entericidin B
HF896_16050	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HF896_16055	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HF896_16060	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HF896_16070	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HF896_16075	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HF896_16080	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HF896_16085	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HF896_16090	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HF896_16095	ENOG4108VIA	integral membrane protein
HF896_16115	ENOG4105EVB	acetyltransferase
HF896_16120	ENOG4105E2K	Glycosyl transferase (Group 1
HF896_16130	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HF896_16135	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HF896_16145	ENOG4105CRK	lysyL-tRNA synthetase
HF896_16155	ENOG4105CP9	extracellular ligand-binding receptor
HF896_16160	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_16165	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HF896_16170	ENOG4105C0Z	ABC transporter
HF896_16175	ENOG4108IV0	ABC, transporter
HF896_16185	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HF896_16190	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HF896_16195	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HF896_16200	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HF896_16205	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HF896_16210	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HF896_16220	ENOG4105C3F	Signal peptidase i
HF896_16225	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HF896_16230	ENOG4105C0H	protease
HF896_16245	ENOG4105EMN	RNA polymerase sigma factor
HF896_16255	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HF896_16260	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HF896_16265	ENOG4105CHR	reductase
HF896_16270	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HF896_16275	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HF896_16280	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HF896_16285	ENOG4105VGS	50s ribosomal protein l32
HF896_16290	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HF896_16295	ENOG4108UHJ	MAF-like protein
HF896_16300	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HF896_16305	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HF896_16315	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HF896_16320	ENOG4105EI2	Pseudouridine synthase
HF896_16325	ENOG4105C03	ribonuclease
HF896_16330	ENOG4105D1Q	UPF0246 protein
HF896_16340	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HF896_16345	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HF896_16350	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HF896_16355	ENOG4107RSM	transcriptional regulator
HF896_16365	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_16370	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_16380	ENOG4105DMF	Dehydrogenase
HF896_16385	ENOG41090EK	ompa motb domain protein
HF896_16390	ENOG4105BZU	Histidine kinase
HF896_16395	ENOG4108WS1	
HF896_16400	ENOG4105BZ4	penicillin-binding protein
HF896_16410	ENOG4105IYB	L-carnitine dehydratase bile acid-inducible protein F
HF896_16415	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_16425	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_16430	ENOG4105HDK	L-asparaginase
HF896_16440	ENOG4105DUM	transcriptional regulator, lysR family
HF896_16445	ENOG4107S1Q	Phosphatase
HF896_16460	ENOG4105CH7	arginosuccinase
HF896_16465	ENOG4108HRK	Histidine kinase
HF896_16470	ENOG4105D01	(LipO)protein
HF896_16475	ENOG4105ED1	spovr family
HF896_16480	ENOG4106AKX	UPF0229 protein
HF896_16485	ENOG4105CYN	Serine protein kinase
HF896_16495	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
HF896_16500	ENOG4105VIG	Sec-independent protein translocase protein TatC
HF896_16515	ENOG4105CPC	Aldo Keto reductase
HF896_16525	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HF896_16540	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HF896_16550	ENOG4105CSM	endonuclease III
HF896_16560	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HF896_16565	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HF896_16575	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HF896_16610	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HF896_16615	ENOG4107RZC	phospholipase d
HF896_16620	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HF896_16625	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HF896_16635	ENOG4107RGH	Aldehyde dehydrogenase
HF896_16645	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HF896_16650	ENOG4108ZAF	Molybdopterin
HF896_16670	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HF896_16680	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HF896_16685	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HF896_16690	ENOG4105D98	threonine synthase
HF896_16695	ENOG4107PBH	Toxic component of a toxin-antitoxin (TA) module. A
HF896_16705	ENOG4105D6E	homoserine dehydrogenase
HF896_16710	ENOG4105CHM	Aminotransferase
HF896_16730	ENOG4105CC9	acyl-Coa dehydrogenase
HF896_16735	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_16740	ENOG4105C10	Electron transfer flavoprotein
HF896_16745	ENOG4105BZJ	Electron transfer flavoprotein
HF896_16755	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_16765	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_16770	ENOG4105E39	Enoyl-CoA hydratase
HF896_16775	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_16795	ENOG4105E39	Enoyl-CoA hydratase
HF896_16800	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HF896_16815	ENOG4105D2B	acyl-CoA dehydrogenase
HF896_16820	ENOG4105CC9	acyl-Coa dehydrogenase
HF896_16825	ENOG4105E39	Enoyl-CoA hydratase
HF896_16845	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_16850	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HF896_16855	ENOG4105CHR	reductase
HF896_16870	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HF896_16880	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HF896_16885	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HF896_16890	ENOG4105E0A	ABC, transporter
HF896_16895	ENOG4105EHG	Permease protein
HF896_16905	ENOG4108YZT	Adenosylcobinamide kinase
HF896_16910	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HF896_16915	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HF896_16930	ENOG4105BZU	Histidine kinase
HF896_16935	ENOG4108ESY	Metal dependent phosphohydrolase
HF896_16945	ENOG4105D4P	Coproporphyrinogen iii oxidase
HF896_16950	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HF896_16985	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HF896_17005	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_17025	ENOG4105DRR	Transcriptional regulator, GntR family
HF896_17030	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HF896_17035	ENOG4108UWD	Iron-storage protein
HF896_17045	ENOG4105C01	Dihydroxy-acid dehydratase
HF896_17050	ENOG4105C01	Dihydroxy-acid dehydratase
HF896_17060	ENOG4105W2Z	cytochrome C, class I
HF896_17065	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HF896_17070	ENOG4105D60	lipoprotein releasing system transmembrane protein
HF896_17080	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HF896_17085	ENOG4105C8Q	Methyl-accepting chemotaxis
HF896_17090	ENOG4105DB7	PHP domain protein
HF896_17095	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HF896_17100	ENOG4105C8Q	Methyl-accepting chemotaxis
HF896_17105	ENOG4108Z4T	Peptidase M50
HF896_17110	ENOG4105C31	Tryptophanyl-tRNA synthetase
HF896_17115	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HF896_17145	ENOG4105FFC	UPF0187 protein
HF896_17150	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HF896_17165	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HF896_17170	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HF896_17175	ENOG4105W5Q	DNA repair protein (RadC
HF896_17185	ENOG4105C98	muts2 protein
HF896_17195	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HF896_17200	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HF896_17210	ENOG4105CAR	Terminase, large subunit
HF896_17235	ENOG4105CV6	ABC transporter, permease
HF896_17240	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HF896_17260	ENOG4105QAX	Iron-sulfur
HF896_17265	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HF896_17295	ENOG4108IEG	Formate dehydrogenase Alpha subunit
HF896_17315	ENOG4107EJG	GntR family transcriptional regulator
HF896_17320	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_17325	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_17360	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HF896_17375	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HF896_17390	ENOG4105DKK	Benzoate
HF896_17395	ENOG4105DFA	alanine racemase domain protein
HF896_17400	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HF896_17405	ENOG4108ZX5	transcriptional regulator
HF896_17450	ENOG4108IYU	L-aspartate oxidase
HF896_17465	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HF896_17470	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HF896_17475	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HF896_17480	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HF896_17485	ENOG4105DUM	transcriptional regulator, lysR family
HF896_17515	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HF896_17520	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HF896_17530	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HF896_17535	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HF896_17540	ENOG4105CN1	protease
HF896_17545	ENOG4105D06	uba thif-type nad fad binding protein
HF896_17555	ENOG4105WH1	Two component transcriptional regulator luxr family
HF896_17565	ENOG4106H29	UPF0391 membrane protein
HF896_17575	ENOG4105K3G	Periplasmic Protein
HF896_17580	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HF896_17585	ENOG4106H78	methyltransferase
HF896_17605	ENOG4107YNJ	LysR family Transcriptional regulator
HF896_17610	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
HF896_17620	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
HF896_17625	ENOG4105CMJ	mandelate racemase muconate lactonizing
HF896_17635	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HF896_17645	ENOG4107QM5	aconitate hydratase
HF896_17655	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HF896_17660	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HF896_17685	ENOG4105DHQ	Histidine kinase
HF896_17735	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HF896_17750	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HF896_17775	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
HF896_17785	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
HF896_17790	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HF896_17795	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HF896_17800	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HF896_17805	ENOG41081UC	Inherit from COG: Competence protein
HF896_17810	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HF896_17815	ENOG4105EXG	Transcriptional regulator
HF896_17830	ENOG410829K	Lysine exporter protein (Lyse ygga)
HF896_17835	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HF896_17840	ENOG4105FDP	GntR family transcriptional regulator
HF896_17850	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HF896_17855	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HF896_17875	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HF896_17885	ENOG4105CH2	amidohydrolase
HF896_17895	ENOG41064T2	transcriptional regulator, lysR family
HF896_17915	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_17920	ENOG4107QNJ	CoA-transferase subunit B
HF896_17930	ENOG4107HP6	Transcriptional regulator
HF896_17945	ENOG4106RE7	Cytochrome
HF896_17950	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HF896_17965	ENOG4105CMD	Transcriptional regulator, GntR family
HF896_17970	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_18020	ENOG4105NAA	Cytochrome C oxidase, subunit II
HF896_18025	ENOG4107RQ2	Cytochrome c oxidase, subunit I
HF896_18030	ENOG4108YJ5	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HF896_18050	ENOG4108KAG	Cytochrome C oxidase, subunit I
HF896_18055	ENOG4108EX3	reductase
HF896_18065	ENOG4105DHQ	Histidine kinase
HF896_18070	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HF896_18075	ENOG4105C0H	protease
HF896_18085	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
HF896_18090	ENOG4108UCS	ABC, transporter
HF896_18100	ENOG4105CD3	dihydroorotase
HF896_18105	ENOG4105CXT	aspartate transcarbamylase
HF896_18110	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HF896_18115	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HF896_18120	ENOG4108UJU	UPF0301 protein
HF896_18130	ENOG4105C8Q	Methyl-accepting chemotaxis
HF896_18140	ENOG4105M3Z	response regulator
HF896_18145	ENOG4108UNF	response regulator
HF896_18150	ENOG4105VCQ	rubredoxin
HF896_18165	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HF896_18170	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HF896_18175	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HF896_18180	ENOG4105W39	Membrane
HF896_18195	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
HF896_18210	ENOG4105JJR	Histidine kinase
HF896_18220	ENOG4105C3G	gtp-binding protein
HF896_18225	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HF896_18240	ENOG4105E39	Enoyl-CoA hydratase
HF896_18255	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HF896_18260	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HF896_18265	ENOG4105CRE	cytochrome C
HF896_18275	ENOG4107TUY	Histidine kinase
HF896_18280	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HF896_18290	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HF896_18295	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HF896_18315	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HF896_18320	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HF896_18325	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HF896_18330	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HF896_18340	ENOG4105DFU	Cell wall formation (By similarity)
HF896_18350	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HF896_18355	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HF896_18360	ENOG4105CNI	cell division protein FtsW
HF896_18365	ENOG4105IPS	esterase
HF896_18375	ENOG4105XUA	cytochrome c
HF896_18385	ENOG4105EMN	RNA polymerase sigma factor
HF896_18400	ENOG4105E2X	shikimate dehydrogenase
HF896_18405	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HF896_18420	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HF896_18435	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HF896_18445	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HF896_18460	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_18465	ENOG4105CHR	reductase
HF896_18475	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HF896_18485	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HF896_18490	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HF896_18495	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HF896_18500	ENOG4105CPF	Cell wall formation (By similarity)
HF896_18505	ENOG4105DFU	Cell wall formation (By similarity)
HF896_18510	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HF896_18515	ENOG4105CNI	cell division protein FtsW
HF896_18520	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HF896_18525	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HF896_18530	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HF896_18535	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HF896_18540	ENOG4105CJN	penicillin-binding protein
HF896_18550	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HF896_18555	ENOG4108V6E	Cell division protein mraZ
HF896_18560	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HF896_18565	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HF896_18580	ENOG4105CKI	cobalamin synthesis protein
HF896_18590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HF896_18595	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HF896_18605	ENOG4105BZU	Histidine kinase
HF896_18610	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HF896_18615	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HF896_18620	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HF896_18630	ENOG4105BZU	Histidine kinase
HF896_18635	ENOG4105C8Q	Methyl-accepting chemotaxis
HF896_18640	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HF896_18650	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HF896_18660	ENOG4105I08	Pseudouridine synthase
HF896_18685	ENOG4105DZ0	fad dependent oxidoreductase
HF896_18695	ENOG4105EGI	Transcriptional regulator
HF896_18700	ENOG4105CI0	Citrate lyase
HF896_18715	ENOG4105GAK	amidohydrolase 2
HF896_18725	ENOG4108SY4	MarR family Transcriptional regulator
HF896_18730	ENOG4105CHR	reductase
HF896_18735	ENOG4108IPT	Naphthoate synthase
HF896_18745	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_18750	ENOG4105C10	Electron transfer flavoprotein
HF896_18755	ENOG4105BZJ	Electron transfer flavoprotein
HF896_18760	ENOG4105EA8	2-Nitropropane dioxygenase
HF896_18770	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_18780	ENOG4108UKI	Enoyl-CoA hydratase
HF896_18785	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_18790	ENOG4105CC9	acyl-Coa dehydrogenase
HF896_18795	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_18800	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HF896_18805	ENOG4105CBN	LysR family transcriptional regulator
HF896_18835	ENOG4105D0M	Protease HtpX homolog
HF896_18845	ENOG4105EKE	dihydroorotase
HF896_18855	ENOG4105K78	MarR family Transcriptional regulator
HF896_18860	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HF896_18865	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HF896_18870	ENOG4105CP9	extracellular ligand-binding receptor
HF896_18880	ENOG4108Z9W	Outer membrane porin
HF896_18885	ENOG4105CSH	Transporter
HF896_18925	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HF896_18930	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HF896_18950	ENOG4107QX3	carboxylase
HF896_18955	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_18970	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
HF896_18975	ENOG4105CP9	extracellular ligand-binding receptor
HF896_18980	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_18985	ENOG4105C0Z	ABC transporter
HF896_18990	ENOG4108IV0	ABC, transporter
HF896_18995	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
HF896_19000	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_19005	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HF896_19015	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
HF896_19025	ENOG4105DEF	Extracellular solute-binding protein, family 5
HF896_19035	ENOG4105BZU	Histidine kinase
HF896_19040	ENOG4105K5B	UPF0225 protein
HF896_19090	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_19100	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_19105	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
HF896_19110	ENOG41077A9	carbonic anhydrase
HF896_19115	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_19120	ENOG4108Z6Z	Transcriptional regulator
HF896_19150	ENOG4105C5H	ABC transporter
HF896_19155	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HF896_19160	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
HF896_19165	ENOG4105BZU	Histidine kinase
HF896_19170	ENOG4108V3W	Chemotaxis protein, CheW
HF896_19175	ENOG4105CBS	Chea signal transduction histidine kinase
HF896_19180	ENOG4107YTP	response regulator receiver protein
HF896_19195	ENOG4105WH1	Two component transcriptional regulator luxr family
HF896_19200	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HF896_19205	ENOG4105VS8	Flagellar biosynthetic protein fliq
HF896_19210	ENOG4105CN7	Flagellar biosynthetic protein FliP
HF896_19220	ENOG4105DD5	Flagellar motor switch protein
HF896_19225	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HF896_19245	ENOG4108JIR	Flagellum-specific ATP synthase
HF896_19255	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HF896_19260	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HF896_19280	ENOG4105DTS	flagellar hook-associated
HF896_19290	ENOG4105I03	Flagellin
HF896_19295	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
HF896_19300	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HF896_19305	ENOG4107RD7	Flagellar Motor Protein, MotA
HF896_19310	ENOG4105ER2	Ompa motb domain protein
HF896_19315	ENOG4108VYJ	response regulator receiver protein
HF896_19320	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HF896_19325	ENOG4105D00	flagellar biosynthetic protein flhB
HF896_19330	ENOG4105D7B	Flagellar biosynthesis protein flha
HF896_19335	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HF896_19345	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HF896_19360	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
HF896_19365	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HF896_19370	ENOG4108ZC9	flagellar basal-body rod protein flgc
HF896_19375	ENOG4105W00	Flagellar hook capping protein
HF896_19380	ENOG4105BZE	flagellar hook protein, FlgE
HF896_19385	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HF896_19390	ENOG4105CGA	flagellar basal-body rod protein FlgG
HF896_19400	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HF896_19405	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HF896_19415	ENOG4105DTJ	flagellar hook-associated protein
HF896_19425	ENOG4105EA8	2-Nitropropane dioxygenase
HF896_19430	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HF896_19440	ENOG4105T38	integral membrane protein
HF896_19445	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HF896_19450	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HF896_19455	ENOG4105C7B	Threonine dehydratase
HF896_19530	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HF896_19535	ENOG4105C25	Primosomal protein n'
HF896_19540	ENOG4105CHU	acetyl-coa acetyltransferase
HF896_19545	ENOG4108UKI	Enoyl-CoA hydratase
HF896_19550	ENOG4108IQE	Amp-dependent synthetase and ligase
HF896_19555	ENOG4108IV0	ABC, transporter
HF896_19575	ENOG4105C0Z	ABC transporter
HF896_19585	ENOG4105RK9	auxin efflux carrier
HF896_19590	ENOG4105C4R	Atp-dependent dna helicase
HF896_19600	ENOG4105HDD	phospholipase
HF896_19605	ENOG4105E6M	Sulphatase-modifying factor protein
HF896_19610	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HF896_19625	ENOG4105ERH	Fumarylacetoacetate hydrolase
HF896_19630	ENOG4108Z9W	Outer membrane porin
HF896_19635	ENOG4108PVQ	transcriptional regulator
HF896_19645	ENOG4107YZX	Universal stress protein
HF896_19650	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HF896_19680	ENOG4105JSC	dimethylmenaquinone methyltransferase
HF896_19690	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_19695	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HF896_19725	ENOG4105E1J	oxidoreductase
HF896_19750	ENOG4105M2Z	protein tyrosine serine phosphatase
HF896_19765	ENOG4108FUF	Transcriptional regulator, IclR family
HF896_19805	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_19885	ENOG4105HMI	Membrane
HF896_19890	ENOG4105DUM	transcriptional regulator, lysR family
HF896_19930	ENOG4108ZT0	50S ribosomal protein l17
HF896_19935	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HF896_19940	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HF896_19945	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HF896_19950	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HF896_19960	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HF896_19965	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HF896_19970	ENOG4105VPB	50S ribosomal protein L30
HF896_19975	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HF896_19980	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HF896_19985	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HF896_19990	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HF896_19995	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HF896_20000	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HF896_20005	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HF896_20010	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HF896_20015	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HF896_20020	ENOG4105E98	transcriptional regulator DeoR family
HF896_20025	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HF896_20030	ENOG4105II7	pyrroline-5-carboxylate reductase
HF896_20040	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HF896_20050	ENOG4105C5Q	Transcriptional regulator
HF896_20055	ENOG4105CB5	ATP-dependent DNA helicase recG
HF896_20060	ENOG4105CPI	Metal Dependent Phosphohydrolase
HF896_20065	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HF896_20075	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HF896_20085	ENOG4105F04	LysR family Transcriptional regulator
HF896_20090	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HF896_20095	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HF896_20105	ENOG4107QYG	anthranilate phosphoribosyltransferase
HF896_20110	ENOG4105DDQ	anthranilate synthase
HF896_20160	ENOG4107YH6	single-stranded DNA-binding protein
HF896_20165	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HF896_20170	ENOG4105NI8	Cytosine-specific methyltransferase
HF896_20280	ENOG4105RHY	Pfam:UPF0157
HF896_20370	ENOG4105W5Q	DNA repair protein (RadC
HF896_20440	ENOG4108IG5	Transcriptional regulator
HF896_20445	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_20450	ENOG4108IV0	ABC, transporter
HF896_20465	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_20470	ENOG4108IQE	Amp-dependent synthetase and ligase
HF896_20475	ENOG4105C0Z	ABC transporter
HF896_20495	ENOG4105E39	Enoyl-CoA hydratase
HF896_20520	ENOG4105D6J	arsenicaL-resistance protein
HF896_20545	ENOG41085FC	arsR family transcriptional regulator
HF896_20595	ENOG4105C8Q	Methyl-accepting chemotaxis
HF896_20600	ENOG4105BZU	Histidine kinase
HF896_20605	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HF896_20615	ENOG4105DJV	ribulose-phosphate 3-epimerase
HF896_20620	ENOG4105NWN	ApaG protein
HF896_20635	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
HF896_20640	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HF896_20645	ENOG4107XI7	Tetr family transcriptional regulator
HF896_20650	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HF896_20655	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HF896_20660	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HF896_20665	ENOG4105D0S	secretion protein (HlyD
HF896_20670	ENOG4105CJ1	ABC, transporter
HF896_20675	ENOG4105CMI	transporter
HF896_20685	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HF896_20690	ENOG4108ZAI	phosphatidylglycerophosphatase a
HF896_20700	ENOG4105C8Q	Methyl-accepting chemotaxis
HF896_20705	ENOG4105BZU	Histidine kinase
HF896_20720	ENOG4106RHG	Yeca family
HF896_20730	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HF896_20735	ENOG4105C8Q	Methyl-accepting chemotaxis
HF896_20745	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HF896_20750	ENOG4108IUZ	ABC transporter
HF896_20760	ENOG4108Z33	Thiol disulfide Interchange Protein
HF896_20770	ENOG4105C75	arginyL-tRNA synthetase
HF896_20785	ENOG4105CK2	sodium dicarboxylate symporter
HF896_20805	ENOG4107QP3	malate synthase g
HF896_20815	ENOG41084KP	4-oxalocrotonate tautomerase
HF896_20825	ENOG4105E7A	Glutamine amidotransferase
HF896_20855	ENOG4105D7Z	glutathione synthase
HF896_20860	ENOG4105DKK	Benzoate
HF896_20865	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HF896_20875	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HF896_20880	ENOG4105C1A	potassium transporter peripheral membrane
HF896_20885	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HF896_20910	ENOG4105DJF	DNA polymerase III, delta' subunit
HF896_20920	ENOG4105C8T	Leucyl-tRNA synthetase
HF896_20925	ENOG4105CUY	Mechanosensitive ion channel
HF896_20930	ENOG4105C26	Dehydrogenase
HF896_20940	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HF896_20950	ENOG4105BZU	Histidine kinase
HF896_20955	ENOG4105SG9	biopolymer transport protein, ExbD
HF896_20970	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HF896_20975	ENOG41090R7	Ferric uptake
HF896_20980	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
HF896_20985	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HF896_20990	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HF896_20995	ENOG4105C8V	SAICAR synthetase
HF896_21000	ENOG4105K63	Thioredoxin
HF896_21005	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HF896_21010	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HF896_21015	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HF896_21065	ENOG4105EIF	outer membrane protein W
HF896_21075	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
HF896_21080	ENOG41072GX	Peptidase M22 Glycoprotease
HF896_21095	ENOG4107QUT	magnesium and cobalt transport protein CorA
HF896_21115	ENOG4105CEY	Amp-dependent synthetase and ligase
HF896_21120	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HF896_21125	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HF896_21135	ENOG4105D2N	Aldolase
HF896_21140	ENOG4105CA9	Pyruvate kinase
HF896_21145	ENOG4107RAQ	aminopeptidase
HF896_21150	ENOG4105E39	Enoyl-CoA hydratase
HF896_21180	ENOG4105GZI	Transcriptional regulator
HF896_21185	ENOG4108S0S	Nucleotidyl transferase
HF896_21190	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HF896_21195	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HF896_21210	ENOG4105DND	Transcriptional regulator
HF896_21215	ENOG4105GAK	amidohydrolase 2
HF896_21270	ENOG4105EMY	transcriptional regulator
HF896_21280	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
HF896_21290	ENOG4106IUH	DTW domain containing protein
HF896_21315	ENOG4105CD5	CoA-binding domain protein
HF896_21320	ENOG4105CYM	Glutathione S-transferase
HF896_21325	ENOG4108KEZ	Dehydrogenase
HF896_21335	ENOG4105DXI	Major Facilitator superfamily
HF896_21345	ENOG4105C26	Dehydrogenase
HF896_21365	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_21380	ENOG4105E39	Enoyl-CoA hydratase
HF896_21385	ENOG4107258	Transcriptional regulator
HF896_21390	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HF896_21410	ENOG4105CB2	alcohol dehydrogenase
HF896_21420	ENOG410900P	UPF0336 protein
HF896_21430	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HF896_21435	ENOG4108SY4	MarR family Transcriptional regulator
HF896_21460	ENOG4105DHQ	Histidine kinase
HF896_21485	ENOG4105C4Y	ABC transporter
HF896_21510	ENOG4105CJP	fad dependent oxidoreductase
HF896_21515	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HF896_21520	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HF896_21525	ENOG4105EW9	transcriptional regulator AsnC family
HF896_21535	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HF896_21540	ENOG4108004	Modulates RecA activity (By similarity)
HF896_21550	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HF896_21555	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HF896_21560	ENOG4105VIE	preprotein translocase, subunit YajC
HF896_21570	ENOG4105F7P	transcriptional regulator AsnC family
HF896_21575	ENOG4107SFI	Major Facilitator superfamily
HF896_21580	ENOG4105CA3	membrane-bound lytic murein transglycosylase
HF896_21590	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HF896_21595	ENOG4105BZU	Histidine kinase
HF896_21610	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HF896_21625	ENOG4108U78	Glutathione S-transferase
HF896_21630	ENOG4107QTF	adenylosuccinate lyase
HF896_21635	ENOG4108VWS	Yaeq family
HF896_21650	ENOG4108ZCF	integral membrane protein
HF896_21660	ENOG4107RSM	transcriptional regulator
HF896_21670	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_21675	ENOG41086DT	Membrane protein of unknown function
HF896_21680	ENOG4105ERG	peptidase m48, ste24p
HF896_21685	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HF896_21695	ENOG4105YWY	
HF896_21705	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HF896_21710	ENOG4108UW8	fha domain-containing protein
HF896_21720	ENOG4108ZCF	integral membrane protein
HF896_21725	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HF896_21730	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HF896_21735	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HF896_21740	ENOG4105C79	DNA protecting protein DprA
HF896_21750	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HF896_21760	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HF896_21775	ENOG4105BZA	Phosphoglycerate kinase
HF896_21790	ENOG4108Q5Y	Membrane
HF896_21795	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
HF896_21815	ENOG4105C8Q	Methyl-accepting chemotaxis
HF896_21825	ENOG4107RDB	Major Facilitator
HF896_21840	ENOG410846T	CoA-transferase family III
HF896_21860	ENOG4105CHR	reductase
HF896_21870	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_21875	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_21880	ENOG4108IPT	Naphthoate synthase
HF896_21890	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HF896_21895	ENOG4105F04	LysR family Transcriptional regulator
HF896_21900	ENOG4105C7F	AcnD-accessory protein PrpF
HF896_21910	ENOG4108Z9W	Outer membrane porin
HF896_21925	ENOG41079YP	Citrate utilization protein b
HF896_21935	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HF896_21940	ENOG4107QX3	carboxylase
HF896_21945	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HF896_21955	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HF896_21960	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
HF896_21980	ENOG4107ENK	receptor
HF896_22000	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_22010	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HF896_22015	ENOG4108R6K	riboflavin synthase, subunit alpha
HF896_22020	ENOG410829K	Lysine exporter protein (Lyse ygga)
HF896_22025	ENOG4105E0F	Histidine kinase
HF896_22030	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HF896_22045	ENOG4105E3J	oxidoreductase
HF896_22050	ENOG4108VKM	cytochrome b561
HF896_22070	ENOG4105CJ2	(LipO)protein
HF896_22085	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HF896_22105	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_22110	ENOG4107258	Transcriptional regulator
HF896_22120	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_22135	ENOG4105C1G	acyl-Coa dehydrogenase
HF896_22150	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HF896_22210	ENOG4105EVZ	LysR family transcriptional regulator
HF896_22215	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HF896_22220	ENOG4105C26	Dehydrogenase
HF896_22225	ENOG4105BZU	Histidine kinase
HF896_22230	ENOG4108PVQ	transcriptional regulator
HF896_22240	ENOG4105C32	Amino acid ABC transporter (Permease)
HF896_22245	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HF896_22250	ENOG4105C0Z	ABC transporter
HF896_22255	ENOG4108IV0	ABC, transporter
HF896_22260	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HF896_22270	ENOG4105C6K	Malic enzyme
HF896_22285	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HF896_22290	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HF896_22295	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HF896_22300	ENOG4105EHM	Aminoglycoside phosphotransferase
HF896_22305	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HF896_22320	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HF896_22330	ENOG4105BZU	Histidine kinase
HF896_22335	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HF896_22340	ENOG4105DWV	Homoserine O-trans-acetylase
HF896_22350	ENOG4105VFU	Rna-binding protein
HF896_22355	ENOG4105VFU	Rna-binding protein
HF896_22360	ENOG4107FW0	short-chain dehydrogenase reductase
HF896_22370	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HF896_22375	ENOG4105C2X	Arabinose 5-phosphate isomerase
HF896_22385	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HF896_22400	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HF896_22405	ENOG4107RP9	extracellular solute-binding protein, family 3
HF896_22410	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HF896_22435	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HF896_22440	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HF896_22450	ENOG4108JQ6	ABC transporter
HF896_22455	ENOG4105D44	asparaginase
HF896_22475	ENOG4105DEF	Extracellular solute-binding protein, family 5
HF896_22480	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HF896_22485	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HF896_22490	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HF896_22495	ENOG4105VG0	50S ribosomal protein l34