locus-tag	class	description
LSG31_00025	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LSG31_00035	COG2155	Conserved Protein
LSG31_00060	COG0697	spore germination
LSG31_00065	COG1187	pseudouridine synthase activity
LSG31_00070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LSG31_00070	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LSG31_00105	COG3619	membrane
LSG31_00110	COG4608	Belongs to the ABC transporter superfamily
LSG31_00115	COG0444	Belongs to the ABC transporter superfamily
LSG31_00120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LSG31_00125	COG0601	transmembrane transport
LSG31_00130	COG0747	negative chemotaxis
LSG31_00145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LSG31_00160	COG1216	Glycosyl transferase, family 2
LSG31_00165	COG1216	Glycosyl transferase, family 2
LSG31_00175	COG4585	Histidine kinase
LSG31_00180	COG2197	response regulator
LSG31_00320	COG1247	-acetyltransferase
LSG31_00335	COG1475	DNA binding
LSG31_00390	COG3547	Transposase (IS116 IS110 IS902 family)
LSG31_00545	COG0582	viral genome integration into host DNA
LSG31_00625	COG1484	DNA-dependent DNA replication
LSG31_00640	COG3723	Recombinational DNA repair protein, rece pathway
LSG31_00645	COG5377	YqaJ viral recombinase family
LSG31_00690	COG1396	sequence-specific DNA binding
LSG31_00720	COG1396	sequence-specific DNA binding
LSG31_00740	COG1396	sequence-specific DNA binding
LSG31_00755	COG1396	sequence-specific DNA binding
LSG31_00780	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LSG31_00785	COG2718	Belongs to the UPF0229 family
LSG31_00790	COG2766	serine protein kinase
LSG31_00810	COG1414	Transcriptional regulator
LSG31_00815	COG0473	3-isopropylmalate dehydrogenase activity
LSG31_00820	COG1271	oxidase subunit
LSG31_00825	COG1294	oxidase, subunit
LSG31_00830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LSG31_00840	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LSG31_00845	COG0328	RNA-DNA hybrid ribonuclease activity
LSG31_00860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LSG31_00865	COG4493	Belongs to the UPF0637 family
LSG31_00875	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_00885	COG0628	permease
LSG31_00890	COG3850	Histidine kinase
LSG31_00890	COG5002	protein histidine kinase activity
LSG31_00895	COG0745	RESPONSE REGULATOR receiver
LSG31_00925	COG2267	carboxylic ester hydrolase activity
LSG31_00930	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LSG31_00940	COG0709	Synthesizes selenophosphate from selenide and ATP
LSG31_00945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LSG31_00945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LSG31_00995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LSG31_01020	COG1742	UPF0060 membrane protein
LSG31_01030	COG2226	methyltransferase
LSG31_01040	COG5002	protein histidine kinase activity
LSG31_01045	COG0745	RESPONSE REGULATOR receiver
LSG31_01050	COG1842	Phage shock protein A
LSG31_01060	COG2217	Heavy metal translocating P-type atpase
LSG31_01075	COG2132	Multicopper oxidase
LSG31_01080	COG2205	protein histidine kinase activity
LSG31_01085	COG0745	RESPONSE REGULATOR receiver
LSG31_01100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LSG31_01110	COG2132	Multicopper oxidase
LSG31_01120	COG0791	NLP P60 protein
LSG31_01120	COG1388	LysM domain
LSG31_01145	COG2909	trisaccharide binding
LSG31_01155	COG1368	sulfuric ester hydrolase activity
LSG31_01160	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LSG31_01170	COG0840	transmembrane signaling receptor activity
LSG31_01175	COG0395	ABC-type sugar transport system, permease component
LSG31_01180	COG1175	transmembrane transport
LSG31_01185	COG1653	transport
LSG31_01190	COG3279	Response regulator of the LytR AlgR family
LSG31_01195	COG2972	Histidine kinase
LSG31_01205	COG1482	cell wall glycoprotein biosynthetic process
LSG31_01210	COG1940	carbohydrate kinase activity
LSG31_01215	COG0383	alpha-mannosidase activity
LSG31_01220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LSG31_01220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LSG31_01220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LSG31_01230	COG2814	Major facilitator Superfamily
LSG31_01235	COG0584	glycerophosphoryl diester phosphodiesterase
LSG31_01240	COG1408	metallophosphoesterase
LSG31_01280	COG3842	ATPase activity
LSG31_01285	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LSG31_01290	COG1840	ABC-type Fe3 transport system, periplasmic component
LSG31_01310	COG1129	ABC transporter
LSG31_01315	COG1879	ABC-type sugar transport system periplasmic component
LSG31_01320	COG1172	Belongs to the binding-protein-dependent transport system permease family
LSG31_01325	COG1172	Belongs to the binding-protein-dependent transport system permease family
LSG31_01330	COG0673	inositol 2-dehydrogenase activity
LSG31_01340	COG0673	inositol 2-dehydrogenase activity
LSG31_01345	COG1082	Xylose isomerase domain protein TIM barrel
LSG31_01350	COG1917	Cupin 2, conserved barrel domain protein
LSG31_01350	COG4977	sequence-specific DNA binding
LSG31_01360	COG0191	fructose-bisphosphate aldolase activity
LSG31_01365	COG1082	Xylose isomerase domain protein TIM barrel
LSG31_01370	COG3962	Belongs to the TPP enzyme family
LSG31_01375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LSG31_01380	COG3718	enzyme involved in inositol metabolism
LSG31_01385	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_01390	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_01415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LSG31_01425	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_01430	COG1115	amino acid carrier protein
LSG31_01440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LSG31_01455	COG2508	Transcriptional regulator
LSG31_01475	COG3829	transcription factor binding
LSG31_01485	COG2271	Major facilitator Superfamily
LSG31_01495	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LSG31_01500	COG4977	sequence-specific DNA binding
LSG31_01500	COG1917	Cupin 2, conserved barrel domain protein
LSG31_01600	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSG31_01605	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_01610	COG0183	Belongs to the thiolase family
LSG31_01615	COG1929	Belongs to the glycerate kinase type-1 family
LSG31_01620	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LSG31_01630	COG1172	Belongs to the binding-protein-dependent transport system permease family
LSG31_01640	COG1129	ABC transporter
LSG31_01645	COG1879	ABC-type sugar transport system periplasmic component
LSG31_01675	COG1172	Belongs to the binding-protein-dependent transport system permease family
LSG31_01680	COG1129	ABC transporter
LSG31_01725	COG1396	sequence-specific DNA binding
LSG31_01760	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LSG31_01790	COG1361	Conserved repeat domain
LSG31_01805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LSG31_01810	COG2197	response regulator
LSG31_01835	COG1368	sulfuric ester hydrolase activity
LSG31_01860	COG4974	Belongs to the 'phage' integrase family
LSG31_01865	COG0582	viral genome integration into host DNA
LSG31_01870	COG4974	Belongs to the 'phage' integrase family
LSG31_02010	COG2186	Transcriptional regulator
LSG31_02015	COG0670	Belongs to the BI1 family
LSG31_02040	COG0514	ATP-dependent DNA helicase (RecQ)
LSG31_02045	COG0860	N-Acetylmuramoyl-L-alanine amidase
LSG31_02050	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LSG31_02055	COG0697	spore germination
LSG31_02080	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LSG31_02085	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LSG31_02110	COG0745	RESPONSE REGULATOR receiver
LSG31_02115	COG3850	Histidine kinase
LSG31_02115	COG5002	protein histidine kinase activity
LSG31_02125	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LSG31_02135	COG0646	methionine synthase
LSG31_02135	COG1410	methionine synthase
LSG31_02140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LSG31_02155	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LSG31_02165	COG3711	transcriptional antiterminator
LSG31_02175	COG1070	Carbohydrate kinase
LSG31_02180	COG1063	alcohol dehydrogenase
LSG31_02185	COG1063	alcohol dehydrogenase
LSG31_02195	COG1175	transmembrane transport
LSG31_02225	COG2814	Major facilitator Superfamily
LSG31_02235	COG1013	pyruvate-flavodoxin oxidoreductase activity
LSG31_02240	COG0674	pyruvate-flavodoxin oxidoreductase activity
LSG31_02240	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LSG31_02250	COG2508	Transcriptional regulator
LSG31_02255	COG0006	proline dipeptidase activity
LSG31_02260	COG1473	amidohydrolase
LSG31_02265	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LSG31_02270	COG2086	electron transfer activity
LSG31_02280	COG2181	nitrate reductase activity
LSG31_02280	COG0247	lactate metabolic process
LSG31_02285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LSG31_02290	COG0697	spore germination
LSG31_02295	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LSG31_02300	COG1027	Aspartate ammonia-lyase
LSG31_02305	COG1126	abc transporter atp-binding protein
LSG31_02310	COG0765	amino acid transport
LSG31_02315	COG0765	amino acid transport
LSG31_02320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LSG31_02325	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_02335	COG1473	amidohydrolase
LSG31_02345	COG2423	ornithine cyclodeaminase activity
LSG31_02350	COG0006	proline dipeptidase activity
LSG31_02355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LSG31_02360	COG0840	transmembrane signaling receptor activity
LSG31_02365	COG2508	Transcriptional regulator
LSG31_02365	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LSG31_02370	COG2176	DNA-directed DNA polymerase activity
LSG31_02375	COG0477	Major facilitator Superfamily
LSG31_02395	COG0488	(ABC) transporter
LSG31_02420	COG2814	Major facilitator Superfamily
LSG31_02425	COG0697	spore germination
LSG31_02460	COG0028	Belongs to the TPP enzyme family
LSG31_02480	COG1960	acyl-CoA dehydrogenase activity
LSG31_02485	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_02490	COG1063	alcohol dehydrogenase
LSG31_02495	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_02500	COG1960	acyl-CoA dehydrogenase activity
LSG31_02505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LSG31_02515	COG3290	protein histidine kinase activity
LSG31_02515	COG3829	transcription factor binding
LSG31_02520	COG2181	nitrate reductase activity
LSG31_02520	COG0247	lactate metabolic process
LSG31_02525	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LSG31_02530	COG2086	electron transfer activity
LSG31_02535	COG0183	Belongs to the thiolase family
LSG31_02540	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSG31_02545	COG2050	protein possibly involved in aromatic compounds catabolism
LSG31_02550	COG1024	Enoyl-CoA hydratase
LSG31_02560	COG1960	acyl-CoA dehydrogenase activity
LSG31_02570	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LSG31_02575	COG0673	inositol 2-dehydrogenase activity
LSG31_02580	COG2271	Major facilitator Superfamily
LSG31_02590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LSG31_02595	COG0028	Belongs to the TPP enzyme family
LSG31_02600	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_02635	COG2271	Major facilitator Superfamily
LSG31_02640	COG0028	Belongs to the TPP enzyme family
LSG31_02650	COG0710	3-dehydroquinate dehydratase activity
LSG31_02660	COG1414	Transcriptional regulator
LSG31_02665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LSG31_02705	COG2427	Protein of unknown function (DUF1641)
LSG31_02710	COG3383	formate dehydrogenase (NAD+) activity
LSG31_02720	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LSG31_02740	COG0287	Prephenate dehydrogenase
LSG31_02750	COG1850	ribulose-bisphosphate carboxylase activity
LSG31_02755	COG2814	Major facilitator Superfamily
LSG31_02765	COG0697	spore germination
LSG31_02770	COG0583	DNA-binding transcription factor activity
LSG31_02785	COG0531	amino acid
LSG31_02800	COG2204	response regulator
LSG31_02805	COG0667	Aldo Keto reductase
LSG31_02815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LSG31_02820	COG1506	peptidase
LSG31_02820	COG0823	Involved in the tonB-independent uptake of proteins
LSG31_02820	COG4946	Tricorn protease homolog
LSG31_02825	COG4166	transmembrane transport
LSG31_02830	COG4608	Belongs to the ABC transporter superfamily
LSG31_02835	COG0444	Belongs to the ABC transporter superfamily
LSG31_02840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LSG31_02845	COG0601	transmembrane transport
LSG31_02855	COG1752	Esterase of the alpha-beta hydrolase superfamily
LSG31_02870	COG0653	protein targeting
LSG31_02895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LSG31_02910	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LSG31_02940	COG0708	Exodeoxyribonuclease III
LSG31_02950	COG3547	Transposase (IS116 IS110 IS902 family)
LSG31_02990	COG0531	amino acid
LSG31_03000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LSG31_03040	COG0557	exoribonuclease II activity
LSG31_03045	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LSG31_03050	COG0148	phosphopyruvate hydratase activity
LSG31_03055	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LSG31_03060	COG0149	triose-phosphate isomerase activity
LSG31_03065	COG0126	phosphoglycerate kinase activity
LSG31_03080	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LSG31_03085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LSG31_03090	COG0351	phosphomethylpyrimidine kinase
LSG31_03100	COG3239	Fatty acid desaturase
LSG31_03105	COG1278	Cold shock
LSG31_03120	COG0745	RESPONSE REGULATOR receiver
LSG31_03125	COG3850	Histidine kinase
LSG31_03125	COG5002	protein histidine kinase activity
LSG31_03130	COG2226	methyltransferase
LSG31_03145	COG5002	protein histidine kinase activity
LSG31_03165	COG1131	(ABC) transporter
LSG31_03170	COG1388	LysM domain
LSG31_03170	COG0791	NLP P60 protein
LSG31_03170	COG3103	Sh3 type 3 domain protein
LSG31_03180	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LSG31_03185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LSG31_03210	COG4585	Histidine kinase
LSG31_03225	COG4213	ABC transporter substrate-binding protein
LSG31_03235	COG4214	carbohydrate transport
LSG31_03240	COG0697	spore germination
LSG31_03260	COG0840	transmembrane signaling receptor activity
LSG31_03260	COG3290	protein histidine kinase activity
LSG31_03270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LSG31_03275	COG0601	transmembrane transport
LSG31_03280	COG0747	negative chemotaxis
LSG31_03285	COG4608	Belongs to the ABC transporter superfamily
LSG31_03290	COG0444	Belongs to the ABC transporter superfamily
LSG31_03295	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LSG31_03305	COG0745	RESPONSE REGULATOR receiver
LSG31_03310	COG4191	Histidine kinase
LSG31_03370	COG0028	Belongs to the TPP enzyme family
LSG31_03380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LSG31_03405	COG1473	amidohydrolase
LSG31_03415	COG5002	protein histidine kinase activity
LSG31_03420	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LSG31_03455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LSG31_03475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LSG31_03480	COG1481	regulation of sporulation
LSG31_03485	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LSG31_03490	COG1660	Displays ATPase and GTPase activities
LSG31_03495	COG1940	carbohydrate kinase activity
LSG31_03500	COG1051	belongs to the nudix hydrolase family
LSG31_03510	COG0457	Tetratricopeptide repeat
LSG31_03515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LSG31_03520	COG0018	arginyl-trna synthetase
LSG31_03525	COG0140	phosphoribosyl-ATP diphosphatase activity
LSG31_03525	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LSG31_03530	COG0107	imidazoleglycerol-phosphate synthase activity
LSG31_03535	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LSG31_03540	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LSG31_03545	COG0131	Imidazoleglycerol-phosphate dehydratase
LSG31_03550	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LSG31_03555	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LSG31_03560	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LSG31_03570	COG0739	heme binding
LSG31_03580	COG3842	ATPase activity
LSG31_03590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LSG31_03595	COG0556	nucleotide-excision repair
LSG31_03620	COG0793	Belongs to the peptidase S41A family
LSG31_03620	COG3409	Peptidoglycan-binding domain 1 protein
LSG31_03625	COG2177	Part of the ABC transporter FtsEX involved in
LSG31_03630	COG2884	Cell division ATP-binding protein ftsE
LSG31_03635	COG2610	gluconate transmembrane transporter activity
LSG31_03640	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_03650	COG3829	transcription factor binding
LSG31_03650	COG3290	protein histidine kinase activity
LSG31_03655	COG0165	Argininosuccinate lyase
LSG31_03660	COG0137	argininosuccinate synthase activity
LSG31_03665	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LSG31_03670	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LSG31_03675	COG0505	Belongs to the CarA family
LSG31_03685	COG0861	Integral membrane protein TerC family
LSG31_03690	COG2050	protein possibly involved in aromatic compounds catabolism
LSG31_03695	COG0840	transmembrane signaling receptor activity
LSG31_03700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LSG31_03705	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LSG31_03710	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LSG31_03715	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LSG31_03725	COG3511	phospholipase C
LSG31_03730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LSG31_03740	COG0653	protein targeting
LSG31_03755	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LSG31_03775	COG0765	amino acid transport
LSG31_03785	COG1216	Glycosyl transferase, family 2
LSG31_03790	COG3958	Transketolase
LSG31_03795	COG3959	Transketolase, thiamine diphosphate binding domain
LSG31_03800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LSG31_03810	COG3547	Transposase (IS116 IS110 IS902 family)
LSG31_03820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LSG31_03825	COG1216	Glycosyl transferase, family 2
LSG31_03840	COG1215	transferase activity, transferring glycosyl groups
LSG31_03845	COG0463	Glycosyl transferase, family 2
LSG31_03865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LSG31_03885	COG2089	acid synthase
LSG31_03905	COG1516	flagellar protein fliS
LSG31_03910	COG2604	Protein of unknown function DUF115
LSG31_03915	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LSG31_03920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LSG31_03925	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LSG31_03930	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LSG31_03945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LSG31_03950	COG1256	bacterial-type flagellum assembly
LSG31_03950	COG4786	Flagellar basal body rod
LSG31_03970	COG1040	competence protein
LSG31_03975	COG1307	EDD domain protein, DegV family
LSG31_03985	COG0484	heat shock protein binding
LSG31_03990	COG0443	Heat shock 70 kDa protein
LSG31_04000	COG3300	MHYT domain
LSG31_04000	COG5001	Diguanylate cyclase
LSG31_04010	COG0579	oxidoreductase
LSG31_04015	COG5002	protein histidine kinase activity
LSG31_04020	COG0745	RESPONSE REGULATOR receiver
LSG31_04025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LSG31_04035	COG0704	Plays a role in the regulation of phosphate uptake
LSG31_04040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LSG31_04045	COG0840	transmembrane signaling receptor activity
LSG31_04045	COG3290	protein histidine kinase activity
LSG31_04065	COG2199	diguanylate cyclase activity
LSG31_04065	COG2200	EAL domain
LSG31_04065	COG3287	FIST C domain
LSG31_04085	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LSG31_04095	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LSG31_04105	COG0726	polysaccharide deacetylase
LSG31_04120	COG2201	protein-glutamate methylesterase activity
LSG31_04130	COG0793	Belongs to the peptidase S41A family
LSG31_04130	COG3409	Peptidoglycan-binding domain 1 protein
LSG31_04145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LSG31_04155	COG0438	transferase activity, transferring glycosyl groups
LSG31_04165	COG2373	Large extracellular alpha-helical protein
LSG31_04175	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LSG31_04185	COG0210	DNA helicase
LSG31_04235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LSG31_04240	COG0662	Cupin 2, conserved barrel domain protein
LSG31_04240	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LSG31_04255	COG0438	transferase activity, transferring glycosyl groups
LSG31_04305	COG0438	transferase activity, transferring glycosyl groups
LSG31_04360	COG1361	Conserved repeat domain
LSG31_04420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LSG31_04480	COG0463	Glycosyl transferase, family 2
LSG31_04505	COG0438	transferase activity, transferring glycosyl groups
LSG31_04510	COG1739	Uncharacterized protein family UPF0029
LSG31_04525	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LSG31_04535	COG4786	Flagellar basal body rod
LSG31_04540	COG4786	Flagellar basal body rod
LSG31_04545	COG1077	Cell shape determining protein MreB Mrl
LSG31_04550	COG1609	Transcriptional regulator
LSG31_04580	COG2814	Major facilitator Superfamily
LSG31_04585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LSG31_04590	COG2186	Transcriptional regulator
LSG31_04595	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LSG31_04600	COG2721	sulfolactate sulfo-lyase activity
LSG31_04610	COG2385	sporulation resulting in formation of a cellular spore
LSG31_04615	COG1607	acyl-coa hydrolase
LSG31_04625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LSG31_04630	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LSG31_04635	COG1085	galactose-1-phosphate uridylyltransferase
LSG31_04640	COG0746	molybdenum cofactor guanylyltransferase activity
LSG31_04660	COG4841	protein insertion into membrane
LSG31_04675	COG3973	AAA domain
LSG31_04695	COG1846	Transcriptional regulator
LSG31_04700	COG1566	PFAM secretion protein HlyD family protein
LSG31_04705	COG2814	Major facilitator Superfamily
LSG31_04715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LSG31_04740	COG0598	Magnesium transport protein CorA
LSG31_04745	COG2814	Major facilitator Superfamily
LSG31_04755	COG0586	Pfam SNARE associated Golgi protein
LSG31_04760	COG0531	amino acid
LSG31_04770	COG1007	ATP synthesis coupled electron transport
LSG31_04775	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSG31_04780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LSG31_04785	COG0713	ATP synthesis coupled electron transport
LSG31_04790	COG0839	Belongs to the complex I subunit 6 family
LSG31_04795	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSG31_04800	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LSG31_04805	COG0649	NAD binding
LSG31_04810	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSG31_04815	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSG31_04820	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSG31_04825	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LSG31_04830	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LSG31_04835	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LSG31_04840	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LSG31_04845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LSG31_04850	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LSG31_04860	COG0356	it plays a direct role in the translocation of protons across the membrane
LSG31_04875	COG0183	Belongs to the thiolase family
LSG31_04880	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LSG31_04885	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LSG31_04890	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LSG31_04910	COG0495	leucyl-tRNA aminoacylation
LSG31_04915	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LSG31_04920	COG4475	Protein of unknown function (DUF436)
LSG31_04925	COG0698	ribose 5-phosphate isomerase
LSG31_04935	COG1971	Probably functions as a manganese efflux pump
LSG31_04940	COG0009	L-threonylcarbamoyladenylate synthase
LSG31_04950	COG2890	protein-(glutamine-N5) methyltransferase activity
LSG31_04960	COG0254	rRNA binding
LSG31_04975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LSG31_04980	COG1494	fructose-1,6-bisphosphatase
LSG31_04995	COG1959	2 iron, 2 sulfur cluster binding
LSG31_05005	COG0719	Fe-S assembly protein
LSG31_05010	COG0822	iron-sulfur transferase activity
LSG31_05015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LSG31_05020	COG0719	Fe-S assembly protein
LSG31_05025	COG0396	ATPase activity
LSG31_05035	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LSG31_05040	COG0191	fructose-bisphosphate aldolase activity
LSG31_05045	COG2204	response regulator
LSG31_05050	COG0504	CTP synthase activity
LSG31_05055	COG3343	RNA polymerase activity
LSG31_05065	COG1960	acyl-CoA dehydrogenase activity
LSG31_05070	COG1024	Enoyl-CoA hydratase
LSG31_05075	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSG31_05080	COG0183	Belongs to the thiolase family
LSG31_05110	COG0010	Belongs to the arginase family
LSG31_05115	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LSG31_05120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LSG31_05140	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LSG31_05150	COG5577	PFAM Coat F domain
LSG31_05165	COG0395	ABC-type sugar transport system, permease component
LSG31_05175	COG2076	Multidrug Resistance protein
LSG31_05180	COG1510	regulation of RNA biosynthetic process
LSG31_05185	COG0517	IMP dehydrogenase activity
LSG31_05190	COG3189	MarR family transcriptional regulator
LSG31_05205	COG0826	peptidase U32
LSG31_05210	COG0826	peptidase U32
LSG31_05225	COG0656	L-ascorbic acid biosynthetic process
LSG31_05235	COG0517	IMP dehydrogenase activity
LSG31_05235	COG4175	Glycine betaine
LSG31_05240	COG1510	regulation of RNA biosynthetic process
LSG31_05250	COG3383	formate dehydrogenase (NAD+) activity
LSG31_05255	COG2116	formate transmembrane transporter activity
LSG31_05265	COG0840	transmembrane signaling receptor activity
LSG31_05270	COG0475	glutathione-regulated potassium exporter activity
LSG31_05270	COG0569	domain protein
LSG31_05285	COG5002	protein histidine kinase activity
LSG31_05295	COG0840	transmembrane signaling receptor activity
LSG31_05300	COG1376	ErfK ybiS ycfS ynhG family protein
LSG31_05305	COG1876	peptidase activity
LSG31_05310	COG0326	Molecular chaperone. Has ATPase activity
LSG31_05325	COG1131	(ABC) transporter
LSG31_05330	COG1725	Transcriptional regulator
LSG31_05355	COG0640	Transcriptional regulator
LSG31_05370	COG0477	Major facilitator Superfamily
LSG31_05375	COG1609	Transcriptional regulator
LSG31_05380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LSG31_05400	COG0346	lactoylglutathione lyase activity
LSG31_05405	COG1361	Conserved repeat domain
LSG31_05405	COG2911	Protein conserved in bacteria
LSG31_05405	COG3266	domain, Protein
LSG31_05415	COG2208	phosphoserine phosphatase activity
LSG31_05460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LSG31_05495	COG3547	Transposase (IS116 IS110 IS902 family)
LSG31_05515	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LSG31_05525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LSG31_05535	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LSG31_05545	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LSG31_05550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LSG31_05565	COG5002	protein histidine kinase activity
LSG31_05570	COG0745	RESPONSE REGULATOR receiver
LSG31_05580	COG2199	diguanylate cyclase activity
LSG31_05580	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LSG31_05585	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LSG31_05595	COG0305	Participates in initiation and elongation during chromosome replication
LSG31_05600	COG1067	ATP-dependent peptidase activity
LSG31_05600	COG0470	DNA polymerase III
LSG31_05625	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LSG31_05630	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LSG31_05635	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LSG31_05640	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_05650	COG0488	(ABC) transporter
LSG31_05665	COG0629	single-stranded DNA binding
LSG31_05670	COG0012	GTP binding
LSG31_05680	COG0243	molybdopterin cofactor binding
LSG31_05685	COG4481	Protein conserved in bacteria
LSG31_05690	COG0668	transmembrane transport
LSG31_05710	COG1811	Na channel or pump
LSG31_05715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LSG31_05720	COG1475	DNA binding
LSG31_05725	COG1192	Involved in chromosome partitioning
LSG31_05730	COG1475	DNA binding
LSG31_05735	COG0357	Ribosomal RNA small subunit methyltransferase G
LSG31_05740	COG0445	tRNA wobble uridine modification
LSG31_05745	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LSG31_05750	COG1847	R3H domain protein
LSG31_05760	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LSG31_05770	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LSG31_05775	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LSG31_05780	COG0592	DNA-directed DNA polymerase activity
LSG31_05785	COG2501	S4 domain
LSG31_05790	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LSG31_05800	COG0187	DNA topoisomerase II activity
LSG31_05810	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LSG31_05845	COG0516	GMP reductase activity
LSG31_05845	COG0517	IMP dehydrogenase activity
LSG31_05850	COG1686	Belongs to the peptidase S11 family
LSG31_05860	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LSG31_05865	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LSG31_05870	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LSG31_05900	COG0004	ammonium transporteR
LSG31_05905	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LSG31_05910	COG0590	tRNA wobble adenosine to inosine editing
LSG31_05920	COG5002	protein histidine kinase activity
LSG31_05925	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LSG31_05930	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LSG31_05935	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LSG31_05975	COG1982	Orn Lys Arg decarboxylase major
LSG31_05980	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LSG31_05985	COG3870	Protein conserved in bacteria
LSG31_05990	COG1728	Protein conserved in bacteria
LSG31_05995	COG0470	DNA polymerase III
LSG31_06005	COG4467	Involved in initiation control of chromosome replication
LSG31_06010	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LSG31_06015	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LSG31_06020	COG2002	toxin-antitoxin pair type II binding
LSG31_06030	COG0084	hydrolase, TatD family'
LSG31_06040	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LSG31_06060	COG4466	Protein conserved in bacteria
LSG31_06070	COG4242	Belongs to the peptidase S51 family
LSG31_06075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LSG31_06075	COG1181	Belongs to the D-alanine--D-alanine ligase family
LSG31_06085	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LSG31_06090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LSG31_06095	COG0251	oxidation-reduction process
LSG31_06105	COG2088	sporulation resulting in formation of a cellular spore
LSG31_06110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LSG31_06115	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LSG31_06120	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LSG31_06135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LSG31_06145	COG2002	toxin-antitoxin pair type II binding
LSG31_06150	COG2244	polysaccharide biosynthetic process
LSG31_06155	COG3956	TIGRFAM MazG family protein
LSG31_06165	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LSG31_06185	COG1098	S1 RNA binding domain
LSG31_06200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LSG31_06200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LSG31_06205	COG2208	phosphoserine phosphatase activity
LSG31_06210	COG2304	oxidoreductase activity
LSG31_06215	COG0515	serine threonine protein kinase
LSG31_06225	COG3610	response to peptide
LSG31_06240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LSG31_06255	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LSG31_06260	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LSG31_06265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LSG31_06270	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LSG31_06275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LSG31_06280	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LSG31_06285	COG1396	sequence-specific DNA binding
LSG31_06290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LSG31_06295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LSG31_06300	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LSG31_06320	COG1309	transcriptional regulator
LSG31_06330	COG3880	PFAM UvrB UvrC protein
LSG31_06335	COG3869	Catalyzes the specific phosphorylation of arginine residues in
LSG31_06340	COG0542	response to heat
LSG31_06345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LSG31_06350	COG0641	radical SAM
LSG31_06355	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LSG31_06365	COG2223	nitrite transmembrane transporter activity
LSG31_06370	COG2181	nitrate reductase activity
LSG31_06380	COG1140	nitrate reductase beta subunit
LSG31_06385	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LSG31_06400	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LSG31_06405	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LSG31_06410	COG1183	phosphatidylcholine synthase activity
LSG31_06415	COG4956	integral membrane protein (PIN domain superfamily)
LSG31_06420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LSG31_06430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LSG31_06435	COG0215	cysteine-tRNA ligase activity
LSG31_06440	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LSG31_06445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LSG31_06450	COG3688	RNA-binding protein containing a PIN domain
LSG31_06460	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LSG31_06465	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LSG31_06470	COG0250	Participates in transcription elongation, termination and antitermination
LSG31_06475	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LSG31_06480	COG0081	regulation of translation
LSG31_06485	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LSG31_06490	COG0222	ribosome binding
LSG31_06495	COG2813	Specifically methylates the guanine in position
LSG31_06500	COG0085	RNA polymerase activity
LSG31_06505	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LSG31_06510	COG1358	cellular component organization or biogenesis
LSG31_06515	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LSG31_06520	COG0049	tRNA binding
LSG31_06525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LSG31_06530	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LSG31_06545	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LSG31_06550	COG0088	Forms part of the polypeptide exit tunnel
LSG31_06555	COG0089	rRNA binding
LSG31_06560	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LSG31_06565	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LSG31_06570	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LSG31_06575	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LSG31_06580	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LSG31_06585	COG0255	Belongs to the universal ribosomal protein uL29 family
LSG31_06595	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LSG31_06605	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LSG31_06610	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LSG31_06615	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LSG31_06620	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LSG31_06625	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LSG31_06630	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LSG31_06635	COG1841	ribosomal large subunit assembly
LSG31_06640	COG0200	Binds to the 23S rRNA
LSG31_06645	COG0201	protein transport
LSG31_06650	COG0563	adenylate kinase activity
LSG31_06655	COG0024	Methionine aminopeptidase
LSG31_06660	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LSG31_06665	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LSG31_06670	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LSG31_06675	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LSG31_06680	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LSG31_06685	COG0202	RNA polymerase activity
LSG31_06690	COG0203	ribosomal protein L17
LSG31_06695	COG0101	tRNA pseudouridine synthase activity
LSG31_06700	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LSG31_06705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LSG31_06710	COG0860	N-Acetylmuramoyl-L-alanine amidase
LSG31_06715	COG0489	protein tyrosine kinase activity
LSG31_06720	COG1316	TRANSCRIPTIONal
LSG31_06735	COG0726	polysaccharide deacetylase
LSG31_06750	COG0586	Pfam SNARE associated Golgi protein
LSG31_06755	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
LSG31_06760	COG0175	sulfate reduction
LSG31_06765	COG0730	response to heat
LSG31_06770	COG2046	Belongs to the sulfate adenylyltransferase family
LSG31_06775	COG1595	DNA-templated transcription, initiation
LSG31_06780	COG5662	AntiSigma factor
LSG31_06785	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LSG31_06795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LSG31_06830	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LSG31_06860	COG4974	Belongs to the 'phage' integrase family
LSG31_06870	COG0583	DNA-binding transcription factor activity
LSG31_06900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LSG31_06925	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LSG31_06930	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LSG31_06950	COG1309	transcriptional regulator
LSG31_06955	COG0667	Aldo Keto reductase
LSG31_06960	COG0656	L-ascorbic acid biosynthetic process
LSG31_06970	COG2814	Major facilitator Superfamily
LSG31_06985	COG0667	Aldo Keto reductase
LSG31_06990	COG1187	pseudouridine synthase activity
LSG31_07010	COG3300	MHYT domain
LSG31_07010	COG5001	Diguanylate cyclase
LSG31_07015	COG0028	Belongs to the TPP enzyme family
LSG31_07030	COG2770	Histidine kinase
LSG31_07030	COG3437	response regulator, receiver
LSG31_07035	COG2271	Major facilitator Superfamily
LSG31_07040	COG2186	Transcriptional regulator
LSG31_07045	COG0277	FAD linked oxidase domain protein
LSG31_07050	COG0247	lactate metabolic process
LSG31_07070	COG2197	response regulator
LSG31_07085	COG0604	alcohol dehydrogenase
LSG31_07090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LSG31_07115	COG1733	regulation of RNA biosynthetic process
LSG31_07125	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LSG31_07130	COG2259	Doxx family
LSG31_07135	COG1741	Belongs to the pirin family
LSG31_07140	COG1309	transcriptional regulator
LSG31_07165	COG2070	2-Nitropropane dioxygenase
LSG31_07205	COG0657	acetylesterase activity
LSG31_07215	COG0583	DNA-binding transcription factor activity
LSG31_07235	COG0446	pyridine nucleotide-disulphide oxidoreductase
LSG31_07240	COG1509	lysine 2,3-aminomutase activity
LSG31_07250	COG2084	Dehydrogenase
LSG31_07255	COG0473	3-isopropylmalate dehydrogenase activity
LSG31_07265	COG0492	ferredoxin-NADP+ reductase activity
LSG31_07275	COG0860	N-Acetylmuramoyl-L-alanine amidase
LSG31_07275	COG3103	Sh3 type 3 domain protein
LSG31_07275	COG4991	sh3 domain protein
LSG31_07305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LSG31_07335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LSG31_07340	COG2323	membrane
LSG31_07350	COG0745	RESPONSE REGULATOR receiver
LSG31_07355	COG5002	protein histidine kinase activity
LSG31_07360	COG1072	(Pantothenic acid kinase))
LSG31_07370	COG0745	RESPONSE REGULATOR receiver
LSG31_07375	COG5002	protein histidine kinase activity
LSG31_07385	COG0785	Cytochrome C biogenesis protein
LSG31_07395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LSG31_07400	COG1937	Protein conserved in bacteria
LSG31_07405	COG2608	mercury ion transmembrane transporter activity
LSG31_07410	COG0521	Mo-molybdopterin cofactor biosynthetic process
LSG31_07435	COG2151	metal-sulfur cluster biosynthetic enzyme
LSG31_07465	COG4263	nitrous-oxide reductase activity
LSG31_07500	COG2223	nitrite transmembrane transporter activity
LSG31_07505	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LSG31_07510	COG1140	nitrate reductase beta subunit
LSG31_07515	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LSG31_07520	COG2181	nitrate reductase activity
LSG31_07530	COG0535	radical SAM domain protein
LSG31_07535	COG3829	transcription factor binding
LSG31_07540	COG4585	Histidine kinase
LSG31_07545	COG2197	response regulator
LSG31_07555	COG1763	Mo-molybdopterin cofactor biosynthetic process
LSG31_07640	COG0840	transmembrane signaling receptor activity
LSG31_07650	COG4585	Histidine kinase
LSG31_07665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LSG31_07670	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LSG31_07675	COG0517	IMP dehydrogenase activity
LSG31_07695	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LSG31_07705	COG0436	Aminotransferase
LSG31_07750	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LSG31_07765	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LSG31_07785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LSG31_07790	COG0765	amino acid transport
LSG31_07795	COG1126	abc transporter atp-binding protein
LSG31_07800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LSG31_07805	COG0390	transport system, permease component
LSG31_07815	COG1765	OsmC-like protein
LSG31_07820	COG0745	RESPONSE REGULATOR receiver
LSG31_07825	COG5002	protein histidine kinase activity
LSG31_07830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LSG31_07835	COG1136	(ABC) transporter
LSG31_07840	COG0577	efflux transmembrane transporter activity
LSG31_07840	COG1136	(ABC) transporter
LSG31_07845	COG3279	Response regulator of the LytR AlgR family
LSG31_07850	COG0427	acetyl-CoA hydrolase
LSG31_07855	COG0640	Transcriptional regulator
LSG31_07860	COG5658	integral membrane protein
LSG31_07915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LSG31_07935	COG2258	MOSC domain
LSG31_07940	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LSG31_07950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LSG31_07955	COG1119	ATPase activity
LSG31_07960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LSG31_07960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LSG31_07965	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LSG31_07970	COG0736	holo-[acyl-carrier-protein] synthase activity
LSG31_07975	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LSG31_07980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LSG31_07985	COG0864	Transcriptional regulator
LSG31_07990	COG2337	Toxic component of a toxin-antitoxin (TA) module
LSG31_08000	COG0750	zinc metalloprotease
LSG31_08005	COG0697	spore germination
LSG31_08020	COG3331	DNA recombination
LSG31_08025	COG1615	UPF0182 protein
LSG31_08030	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LSG31_08035	COG2814	Major facilitator Superfamily
LSG31_08045	COG0477	Major facilitator Superfamily
LSG31_08050	COG1846	Transcriptional regulator
LSG31_08080	COG2084	Dehydrogenase
LSG31_08085	COG0697	spore germination
LSG31_08115	COG0586	Pfam SNARE associated Golgi protein
LSG31_08120	COG1566	PFAM secretion protein HlyD family protein
LSG31_08125	COG1566	PFAM secretion protein HlyD family protein
LSG31_08160	COG1201	RNA secondary structure unwinding
LSG31_08165	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LSG31_08180	COG0180	Tryptophanyl-tRNA synthetase
LSG31_08205	COG2814	Major facilitator Superfamily
LSG31_08210	COG1566	PFAM secretion protein HlyD family protein
LSG31_08215	COG1846	Transcriptional regulator
LSG31_08220	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LSG31_08225	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LSG31_08240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LSG31_08415	COG1556	Lactate utilization protein
LSG31_08420	COG1139	Iron-sulfur cluster binding protein
LSG31_08430	COG0247	lactate metabolic process
LSG31_08435	COG0277	FAD linked oxidase domain protein
LSG31_08440	COG2186	Transcriptional regulator
LSG31_08445	COG1620	l-lactate permease
LSG31_08460	COG0674	pyruvate-flavodoxin oxidoreductase activity
LSG31_08470	COG3253	May function as heme-dependent peroxidase
LSG31_08475	COG2183	response to ionizing radiation
LSG31_08480	COG3706	GGDEF domain
LSG31_08490	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LSG31_08495	COG0802	atpase or kinase
LSG31_08500	COG1214	PFAM Peptidase M22, glycoprotease
LSG31_08505	COG0456	acetyltransferase
LSG31_08510	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LSG31_08530	COG0488	(ABC) transporter
LSG31_08535	COG0671	phosphoesterase, PA-phosphatase related
LSG31_08540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LSG31_08610	COG1546	Belongs to the CinA family
LSG31_08610	COG1058	Belongs to the CinA family
LSG31_08620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LSG31_08625	COG0805	protein transport
LSG31_08640	COG0459	protein refolding
LSG31_08645	COG2096	Adenosyltransferase
LSG31_08650	COG1595	DNA-templated transcription, initiation
LSG31_08670	COG4942	peptidase
LSG31_08675	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LSG31_08675	COG0519	Catalyzes the synthesis of GMP from XMP
LSG31_08680	COG2252	PERMEase
LSG31_08685	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LSG31_08690	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LSG31_08695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LSG31_08700	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LSG31_08705	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LSG31_08710	COG0047	phosphoribosylformylglycinamidine synthase activity
LSG31_08715	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LSG31_08720	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LSG31_08725	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LSG31_08730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LSG31_08740	COG0151	Belongs to the GarS family
LSG31_08775	COG4496	protein, YerC YecD
LSG31_08800	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LSG31_08805	COG2814	Major facilitator Superfamily
LSG31_08810	COG0210	DNA helicase
LSG31_08815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LSG31_08830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LSG31_08835	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LSG31_08840	COG0154	amidase activity
LSG31_08845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LSG31_08850	COG1597	lipid kinase activity
LSG31_08855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LSG31_08870	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LSG31_08895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LSG31_08920	COG2339	peptidase activity
LSG31_08925	COG0840	transmembrane signaling receptor activity
LSG31_08945	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LSG31_08965	COG1368	sulfuric ester hydrolase activity
LSG31_08985	COG2217	Heavy metal translocating P-type atpase
LSG31_08990	COG0697	spore germination
LSG31_09010	COG0784	Response regulator, receiver
LSG31_09010	COG3437	response regulator, receiver
LSG31_09025	COG2909	trisaccharide binding
LSG31_09060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LSG31_09075	COG2132	Multicopper oxidase
LSG31_09080	COG0745	RESPONSE REGULATOR receiver
LSG31_09085	COG2205	protein histidine kinase activity
LSG31_09090	COG2132	Multicopper oxidase
LSG31_09130	COG1509	lysine 2,3-aminomutase activity
LSG31_09150	COG5002	protein histidine kinase activity
LSG31_09170	COG0785	Cytochrome C biogenesis protein
LSG31_09185	COG2217	Heavy metal translocating P-type atpase
LSG31_09195	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LSG31_09200	COG0739	heme binding
LSG31_09210	COG0586	Pfam SNARE associated Golgi protein
LSG31_09220	COG0450	alkyl hydroperoxide reductase
LSG31_09245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LSG31_09260	COG1842	Phage shock protein A
LSG31_09265	COG0745	RESPONSE REGULATOR receiver
LSG31_09270	COG5002	protein histidine kinase activity
LSG31_09290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LSG31_09315	COG1937	Protein conserved in bacteria
LSG31_09320	COG2217	Heavy metal translocating P-type atpase
LSG31_09350	COG1230	cation diffusion facilitator family transporter
LSG31_09370	COG0629	single-stranded DNA binding
LSG31_09420	COG3829	transcription factor binding
LSG31_09420	COG3290	protein histidine kinase activity
LSG31_09425	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_09435	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSG31_09445	COG1960	acyl-CoA dehydrogenase activity
LSG31_09450	COG2045	Belongs to the ComB family
LSG31_09470	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSG31_09475	COG0183	Belongs to the thiolase family
LSG31_09480	COG0318	PFAM AMP-dependent synthetase and ligase
LSG31_09495	COG2271	Major facilitator Superfamily
LSG31_09500	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LSG31_09505	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LSG31_09515	COG0549	Belongs to the carbamate kinase family
LSG31_09525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LSG31_09530	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LSG31_09535	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LSG31_09540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LSG31_09545	COG2508	Transcriptional regulator
LSG31_09580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LSG31_09610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LSG31_09615	COG3002	Belongs to the UPF0753 family
LSG31_09620	COG5609	conserved protein (DUF2294)
LSG31_09625	COG0288	reversible hydration of carbon dioxide
LSG31_09660	COG1175	transmembrane transport
LSG31_09665	COG0395	ABC-type sugar transport system, permease component
LSG31_09670	COG2203	Gaf domain
LSG31_09670	COG2199	diguanylate cyclase activity
LSG31_09670	COG2200	EAL domain
LSG31_09675	COG0582	viral genome integration into host DNA
LSG31_09680	COG2205	protein histidine kinase activity
LSG31_09690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LSG31_09710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LSG31_09715	COG0425	Belongs to the sulfur carrier protein TusA family
LSG31_09715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LSG31_09725	COG0730	response to heat
LSG31_09730	COG2210	Belongs to the sulfur carrier protein TusA family
LSG31_09735	COG0425	Belongs to the sulfur carrier protein TusA family
LSG31_09735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LSG31_09740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LSG31_09740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LSG31_09745	COG2226	methyltransferase
LSG31_09750	COG0745	RESPONSE REGULATOR receiver
LSG31_09755	COG5002	protein histidine kinase activity
LSG31_09760	COG1611	Belongs to the LOG family
LSG31_09765	COG1361	Conserved repeat domain
LSG31_09775	COG1393	Belongs to the ArsC family
LSG31_09840	COG4974	Belongs to the 'phage' integrase family
LSG31_09870	COG0346	lactoylglutathione lyase activity
LSG31_09880	COG4245	von Willebrand factor, type A
LSG31_09890	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
LSG31_09895	COG0738	Major facilitator superfamily
LSG31_09900	COG1349	DNA-binding transcription factor activity
LSG31_09910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LSG31_09915	COG0077	Prephenate dehydratase
LSG31_09915	COG1605	Chorismate mutase
LSG31_09920	COG1764	response to oxidative stress
LSG31_09925	COG1116	anion transmembrane transporter activity
LSG31_09935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LSG31_09945	COG1414	Transcriptional regulator
LSG31_09950	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_09965	COG0129	dihydroxy-acid dehydratase activity
LSG31_09970	COG1414	Transcriptional regulator
LSG31_09980	COG2721	sulfolactate sulfo-lyase activity
LSG31_09985	COG2721	sulfolactate sulfo-lyase activity
LSG31_09995	COG0277	FAD linked oxidase domain protein
LSG31_10030	COG2271	Major facilitator Superfamily
LSG31_10035	COG0697	spore germination
LSG31_10040	COG1683	Conserved Protein
LSG31_10050	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_10065	COG3852	Histidine kinase
LSG31_10070	COG2204	response regulator
LSG31_10075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LSG31_10085	COG0583	DNA-binding transcription factor activity
LSG31_10115	COG4286	Uncharacterised protein family (UPF0160)
LSG31_10120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LSG31_10170	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LSG31_10180	COG1024	Enoyl-CoA hydratase
LSG31_10185	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSG31_10190	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSG31_10195	COG0183	Belongs to the thiolase family
LSG31_10200	COG0183	Belongs to the thiolase family
LSG31_10210	COG3396	Phenylacetate-CoA oxygenase
LSG31_10225	COG2151	metal-sulfur cluster biosynthetic enzyme
LSG31_10230	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_10245	COG1126	abc transporter atp-binding protein
LSG31_10250	COG0765	amino acid transport
LSG31_10260	COG5002	protein histidine kinase activity
LSG31_10270	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LSG31_10295	COG1203	CRISPR-associated helicase, Cas3
LSG31_10310	COG1468	defense response to virus
LSG31_10310	COG1518	maintenance of DNA repeat elements
LSG31_10315	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LSG31_10335	COG1337	RAMP superfamily
LSG31_10350	COG1609	Transcriptional regulator
LSG31_10370	COG0366	Alpha amylase catalytic
LSG31_10375	COG0460	homoserine dehydrogenase
LSG31_10385	COG0559	Belongs to the binding-protein-dependent transport system permease family
LSG31_10405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LSG31_10410	COG3290	protein histidine kinase activity
LSG31_10415	COG2271	Major facilitator Superfamily
LSG31_10425	COG3853	Toxic anion resistance protein (TelA)
LSG31_10430	COG1253	flavin adenine dinucleotide binding
LSG31_10465	COG1755	Isoprenylcysteine carboxyl methyltransferase
LSG31_10470	COG3424	synthase
LSG31_10475	COG0398	Pfam SNARE associated Golgi protein
LSG31_10480	COG0791	NLP P60 protein
LSG31_10480	COG3103	Sh3 type 3 domain protein
LSG31_10480	COG1388	LysM domain
LSG31_10485	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LSG31_10490	COG1914	H( )-stimulated, divalent metal cation uptake system
LSG31_10495	COG4336	lyase activity
LSG31_10500	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LSG31_10505	COG1984	allophanate hydrolase subunit 2
LSG31_10510	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LSG31_10515	COG0436	Aminotransferase
LSG31_10520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LSG31_10525	COG2146	nitrite reductase [NAD(P)H] activity
LSG31_10530	COG2223	nitrite transmembrane transporter activity
LSG31_10535	COG1733	regulation of RNA biosynthetic process
LSG31_10540	COG2271	Major facilitator Superfamily
LSG31_10545	COG0129	dihydroxy-acid dehydratase activity
LSG31_10555	COG1063	alcohol dehydrogenase
LSG31_10560	COG0564	pseudouridine synthase activity
LSG31_10565	COG1129	ABC transporter
LSG31_10570	COG1172	Belongs to the binding-protein-dependent transport system permease family
LSG31_10580	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_10585	COG4154	Belongs to the RbsD FucU family
LSG31_10595	COG1609	Transcriptional regulator
LSG31_10600	COG0667	Aldo Keto reductase
LSG31_10610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LSG31_10645	COG1404	Belongs to the peptidase S8 family
LSG31_10685	COG0412	Dienelactone hydrolase
LSG31_10705	COG4658	electron transport chain
LSG31_10710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LSG31_10720	COG4948	Mandelate Racemase Muconate Lactonizing
LSG31_10725	COG0385	Bile acid
LSG31_10730	COG2337	Toxic component of a toxin-antitoxin (TA) module
LSG31_10740	COG5001	Diguanylate cyclase
LSG31_10740	COG3300	MHYT domain
LSG31_10750	COG1587	Uroporphyrinogen-III synthase
LSG31_10755	COG2124	cytochrome p450
LSG31_10770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LSG31_10780	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LSG31_10795	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LSG31_10810	COG2059	Chromate
LSG31_10815	COG2059	Chromate
LSG31_10820	COG0655	NAD(P)H dehydrogenase (quinone) activity
LSG31_10835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LSG31_10840	COG4715	Zinc finger, swim domain protein
LSG31_10845	COG1349	DNA-binding transcription factor activity
LSG31_10855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LSG31_10855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LSG31_10855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LSG31_10860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LSG31_10875	COG3829	transcription factor binding
LSG31_10880	COG3395	kinase activity
LSG31_10885	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LSG31_10890	COG1929	Belongs to the glycerate kinase type-1 family
LSG31_10895	COG1606	tRNA processing
LSG31_10900	COG3875	lactate racemase activity
LSG31_10905	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LSG31_10910	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LSG31_10915	COG1620	l-lactate permease
LSG31_10925	COG0697	spore germination
LSG31_10935	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LSG31_10965	COG1058	Belongs to the CinA family
LSG31_10965	COG1546	Belongs to the CinA family
LSG31_10970	COG3971	2-oxopent-4-enoate hydratase activity
LSG31_10975	COG4569	acetaldehyde dehydrogenase (acetylating) activity
LSG31_10980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LSG31_10985	COG1606	tRNA processing
LSG31_10990	COG0477	Major facilitator Superfamily
LSG31_10995	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_11015	COG3829	transcription factor binding
LSG31_11015	COG3290	protein histidine kinase activity
LSG31_11020	COG1691	(AIR) carboxylase
LSG31_11040	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LSG31_11045	COG1845	cytochrome c oxidase, subunit III
LSG31_11050	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LSG31_11055	COG0109	protoheme IX farnesyltransferase activity
LSG31_11075	COG0477	Major facilitator Superfamily
LSG31_11090	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LSG31_11115	COG0587	DNA-directed DNA polymerase activity
LSG31_11125	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LSG31_11130	COG0825	malonyl-CoA metabolic process
LSG31_11135	COG0205	6-phosphofructokinase activity
LSG31_11145	COG0824	Thioesterase
LSG31_11150	COG0538	isocitrate dehydrogenase activity
LSG31_11155	COG0039	L-malate dehydrogenase activity
LSG31_11160	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LSG31_11160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LSG31_11165	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LSG31_11170	COG0237	dephospho-CoA kinase activity
LSG31_11175	COG0741	lytic transglycosylase activity
LSG31_11185	COG0438	transferase activity, transferring glycosyl groups
LSG31_11225	COG0584	glycerophosphoryl diester phosphodiesterase
LSG31_11235	COG4948	Mandelate Racemase Muconate Lactonizing
LSG31_11240	COG3858	chitin binding
LSG31_11245	COG0517	IMP dehydrogenase activity
LSG31_11275	COG0739	heme binding
LSG31_11285	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LSG31_11305	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LSG31_11310	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LSG31_11315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LSG31_11320	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LSG31_11325	COG0072	phenylalanine-tRNA ligase activity
LSG31_11330	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LSG31_11345	COG1193	negative regulation of DNA recombination
LSG31_11355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LSG31_11360	COG0460	homoserine dehydrogenase
LSG31_11365	COG0028	Belongs to the TPP enzyme family
LSG31_11370	COG0440	acetolactate synthase activity
LSG31_11375	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LSG31_11380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LSG31_11385	COG0473	3-isopropylmalate dehydrogenase activity
LSG31_11395	COG2197	response regulator
LSG31_11400	COG2972	Histidine kinase
LSG31_11405	COG1653	transport
LSG31_11410	COG1175	transmembrane transport
LSG31_11415	COG0395	ABC-type sugar transport system, permease component
LSG31_11420	COG1486	melibiose metabolic process
LSG31_11425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LSG31_11430	COG2011	ABC-type metal ion transport system permease component
LSG31_11435	COG1464	Belongs to the NlpA lipoprotein family
LSG31_11445	COG1129	ABC transporter
LSG31_11450	COG1172	Belongs to the binding-protein-dependent transport system permease family
LSG31_11455	COG1172	Belongs to the binding-protein-dependent transport system permease family
LSG31_11460	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LSG31_11465	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LSG31_11490	COG0860	N-Acetylmuramoyl-L-alanine amidase
LSG31_11495	COG0632	four-way junction helicase activity
LSG31_11500	COG2255	four-way junction helicase activity
LSG31_11505	COG1191	sigma factor activity
LSG31_11510	COG4447	cellulose binding
LSG31_11515	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LSG31_11520	COG0343	queuine tRNA-ribosyltransferase activity
LSG31_11525	COG1862	Preprotein translocase
LSG31_11535	COG2323	membrane
LSG31_11540	COG2244	polysaccharide biosynthetic process
LSG31_11550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LSG31_11555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LSG31_11560	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LSG31_11560	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LSG31_11565	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LSG31_11570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LSG31_11575	COG1490	D-aminoacyl-tRNA deacylase activity
LSG31_11580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LSG31_11590	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LSG31_11620	COG0248	Ppx GppA phosphatase
LSG31_11625	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LSG31_11630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LSG31_11650	COG0366	Alpha amylase catalytic
LSG31_11655	COG2720	vancomycin resistance protein
LSG31_11665	COG1914	H( )-stimulated, divalent metal cation uptake system
LSG31_11675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LSG31_11680	COG0745	RESPONSE REGULATOR receiver
LSG31_11685	COG5002	protein histidine kinase activity
LSG31_11705	COG2827	Endonuclease containing a URI domain
LSG31_11725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LSG31_11735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LSG31_11740	COG1090	epimerase
LSG31_11750	COG4251	negative regulation of phosphorylation
LSG31_11750	COG5001	Diguanylate cyclase
LSG31_11750	COG2203	Gaf domain
LSG31_11750	COG3706	GGDEF domain
LSG31_11755	COG0667	Aldo Keto reductase
LSG31_11765	COG1609	Transcriptional regulator
LSG31_11770	COG3959	Transketolase, thiamine diphosphate binding domain
LSG31_11775	COG3958	Transketolase
LSG31_11780	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_11785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LSG31_11795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LSG31_11800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LSG31_11805	COG3959	Transketolase, thiamine diphosphate binding domain
LSG31_11810	COG3958	Transketolase
LSG31_11820	COG2814	Major facilitator Superfamily
LSG31_11825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LSG31_11830	COG1024	Enoyl-CoA hydratase
LSG31_11835	COG1802	Transcriptional regulator
LSG31_11845	COG1609	Transcriptional regulator
LSG31_11850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LSG31_11855	COG1869	D-ribose catabolic process
LSG31_11865	COG1172	Belongs to the binding-protein-dependent transport system permease family
LSG31_11900	COG1696	Membrane protein involved in D-alanine export
LSG31_11935	COG0583	DNA-binding transcription factor activity
LSG31_11940	COG0067	glutamate synthase
LSG31_11940	COG0069	glutamate synthase activity
LSG31_11940	COG0070	glutamate synthase
LSG31_11950	COG0673	inositol 2-dehydrogenase activity
LSG31_11955	COG1757	Na H antiporter
LSG31_11965	COG1136	(ABC) transporter
LSG31_11970	COG1136	(ABC) transporter
LSG31_11970	COG0577	efflux transmembrane transporter activity
LSG31_11975	COG2205	protein histidine kinase activity
LSG31_11980	COG5002	protein histidine kinase activity
LSG31_11985	COG0745	RESPONSE REGULATOR receiver
LSG31_11990	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_11995	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LSG31_12000	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LSG31_12005	COG3829	transcription factor binding
LSG31_12005	COG3290	protein histidine kinase activity
LSG31_12035	COG0673	inositol 2-dehydrogenase activity
LSG31_12040	COG1609	Transcriptional regulator
LSG31_12050	COG1175	transmembrane transport
LSG31_12055	COG0395	ABC-type sugar transport system, permease component
LSG31_12070	COG0110	maltose O-acetyltransferase activity
LSG31_12090	COG1653	transport
LSG31_12110	COG0673	inositol 2-dehydrogenase activity
LSG31_12120	COG1609	Transcriptional regulator
LSG31_12130	COG1175	transmembrane transport
LSG31_12135	COG0395	ABC-type sugar transport system, permease component
LSG31_12140	COG1621	beta-fructofuranosidase activity
LSG31_12145	COG0667	Aldo Keto reductase
LSG31_12150	COG1940	carbohydrate kinase activity
LSG31_12155	COG1653	transport
LSG31_12165	COG0395	ABC-type sugar transport system, permease component
LSG31_12170	COG0673	inositol 2-dehydrogenase activity
LSG31_12185	COG1472	Belongs to the glycosyl hydrolase 3 family
LSG31_12190	COG2115	Belongs to the xylose isomerase family
LSG31_12195	COG3250	beta-galactosidase activity
LSG31_12205	COG1653	transport
LSG31_12215	COG0395	ABC-type sugar transport system, permease component
LSG31_12240	COG1175	transmembrane transport
LSG31_12245	COG0395	ABC-type sugar transport system, permease component
LSG31_12250	COG0383	alpha-mannosidase activity
LSG31_12255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LSG31_12260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LSG31_12275	COG0840	transmembrane signaling receptor activity
LSG31_12300	COG1472	Belongs to the glycosyl hydrolase 3 family
LSG31_12310	COG0673	inositol 2-dehydrogenase activity
LSG31_12320	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LSG31_12325	COG2814	Major facilitator Superfamily
LSG31_12330	COG3408	Glycogen debranching enzyme
LSG31_12330	COG3119	arylsulfatase activity
LSG31_12345	COG3119	arylsulfatase activity
LSG31_12350	COG3119	arylsulfatase activity
LSG31_12355	COG3119	arylsulfatase activity
LSG31_12370	COG0395	ABC-type sugar transport system, permease component
LSG31_12385	COG3119	arylsulfatase activity
LSG31_12390	COG3119	arylsulfatase activity
LSG31_12395	COG1940	carbohydrate kinase activity
LSG31_12400	COG3119	arylsulfatase activity
LSG31_12420	COG2271	Major facilitator Superfamily
LSG31_12425	COG3119	arylsulfatase activity
LSG31_12430	COG3119	arylsulfatase activity
LSG31_12435	COG1940	carbohydrate kinase activity
LSG31_12450	COG3119	arylsulfatase activity
LSG31_12450	COG3408	Glycogen debranching enzyme
LSG31_12460	COG0346	lactoylglutathione lyase activity
LSG31_12510	COG1027	Aspartate ammonia-lyase
LSG31_12515	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_12520	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
LSG31_12525	COG1732	Glycine betaine
LSG31_12530	COG1174	glycine betaine transport
LSG31_12535	COG1174	glycine betaine transport
LSG31_12540	COG0517	IMP dehydrogenase activity
LSG31_12540	COG1125	glycine betaine transport
LSG31_12545	COG1070	Carbohydrate kinase
LSG31_12550	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_12555	COG0277	FAD linked oxidase domain protein
LSG31_12560	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LSG31_12585	COG1764	response to oxidative stress
LSG31_12590	COG0564	pseudouridine synthase activity
LSG31_12595	COG0436	Aminotransferase
LSG31_12600	COG1522	sequence-specific DNA binding
LSG31_12605	COG2226	methyltransferase
LSG31_12605	COG0596	Alpha beta hydrolase
LSG31_12605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LSG31_12610	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LSG31_12620	COG1737	Transcriptional regulator
LSG31_12635	COG2226	methyltransferase
LSG31_12645	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LSG31_12660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LSG31_12680	COG0860	N-Acetylmuramoyl-L-alanine amidase
LSG31_12680	COG4991	sh3 domain protein
LSG31_12680	COG3103	Sh3 type 3 domain protein
LSG31_12690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LSG31_12695	COG0124	histidyl-tRNA synthetase
LSG31_12700	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LSG31_12705	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LSG31_12720	COG0463	Glycosyl transferase, family 2
LSG31_12720	COG0457	Tetratricopeptide repeat
LSG31_12725	COG0457	Tetratricopeptide repeat
LSG31_12725	COG0463	Glycosyl transferase, family 2
LSG31_12740	COG1216	Glycosyl transferase, family 2
LSG31_12740	COG0438	transferase activity, transferring glycosyl groups
LSG31_12750	COG0463	Glycosyl transferase, family 2
LSG31_12760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LSG31_12775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LSG31_12780	COG0423	glycine-tRNA ligase activity
LSG31_12790	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LSG31_12795	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LSG31_12800	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LSG31_12815	COG0697	spore germination
LSG31_12830	COG1959	2 iron, 2 sulfur cluster binding
LSG31_12835	COG1104	cysteine desulfurase activity
LSG31_12840	COG0628	permease
LSG31_12845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LSG31_12850	COG4472	Bacterial protein of unknown function (DUF965)
LSG31_12855	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LSG31_12860	COG3906	Belongs to the UPF0473 family
LSG31_12865	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LSG31_12870	COG4122	O-methyltransferase activity
LSG31_12885	COG0352	thiamine-phosphate diphosphorylase activity
LSG31_12890	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LSG31_12895	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LSG31_12910	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LSG31_12940	COG0410	ABC transporter
LSG31_12945	COG0831	urea catabolic process
LSG31_12950	COG0804	urea catabolic process
LSG31_12955	COG0830	nickel cation binding
LSG31_12965	COG0829	nickel cation binding
LSG31_13005	COG0697	spore germination
LSG31_13030	COG1705	Flagellar rod assembly protein muramidase FlgJ
LSG31_13030	COG1388	LysM domain
LSG31_13060	COG0410	ABC transporter
LSG31_13105	COG1388	LysM domain
LSG31_13105	COG3858	chitin binding
LSG31_13130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LSG31_13140	COG4191	Histidine kinase
LSG31_13160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LSG31_13165	COG2323	membrane
LSG31_13170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LSG31_13175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LSG31_13185	COG1131	(ABC) transporter
LSG31_13190	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LSG31_13195	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LSG31_13200	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LSG31_13205	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LSG31_13215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LSG31_13220	COG1534	Rna-binding protein
LSG31_13225	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LSG31_13230	COG1713	HD superfamily hydrolase involved in NAD metabolism
LSG31_13235	COG0799	negative regulation of ribosome biogenesis
LSG31_13240	COG2226	methyltransferase
LSG31_13250	COG1555	photosystem II stabilization
LSG31_13250	COG1596	polysaccharide export
LSG31_13260	COG1388	LysM domain
LSG31_13260	COG0791	NLP P60 protein
LSG31_13270	COG1252	NADH dehydrogenase
LSG31_13275	COG1466	dna polymerase III delta subunit
LSG31_13280	COG0268	Binds directly to 16S ribosomal RNA
LSG31_13300	COG0481	GTPase activity
LSG31_13305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LSG31_13310	COG1420	regulation of RNA biosynthetic process
LSG31_13320	COG0443	Heat shock 70 kDa protein
LSG31_13325	COG0484	heat shock protein binding
LSG31_13335	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LSG31_13340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LSG31_13350	COG1283	sodium-dependent phosphate transmembrane transporter activity
LSG31_13355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LSG31_13360	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LSG31_13365	COG1610	YqeY-like protein
LSG31_13380	COG1702	phosphate starvation-inducible protein PhoH
LSG31_13385	COG1480	7TM receptor with intracellular HD hydrolase
LSG31_13390	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LSG31_13395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LSG31_13400	COG0295	cytidine deaminase activity
LSG31_13405	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LSG31_13415	COG1381	Involved in DNA repair and RecF pathway recombination
LSG31_13420	COG0517	IMP dehydrogenase activity
LSG31_13425	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LSG31_13430	COG0574	Belongs to the PEP-utilizing enzyme family
LSG31_13430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LSG31_13435	COG0358	DNA primase activity
LSG31_13440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LSG31_13450	COG1960	acyl-CoA dehydrogenase activity
LSG31_13455	COG2384	SAM-dependent methyltransferase
LSG31_13460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LSG31_13470	COG2081	HI0933 family
LSG31_13570	COG1063	alcohol dehydrogenase
LSG31_13575	COG1063	alcohol dehydrogenase
LSG31_13580	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_13615	COG0574	Belongs to the PEP-utilizing enzyme family
LSG31_13615	COG3848	Pyruvate phosphate dikinase
LSG31_13625	COG3944	biosynthesis protein
LSG31_13630	COG0489	protein tyrosine kinase activity
LSG31_13645	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LSG31_13650	COG1086	Polysaccharide biosynthesis protein
LSG31_13655	COG0438	transferase activity, transferring glycosyl groups
LSG31_13660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LSG31_13665	COG1316	TRANSCRIPTIONal
LSG31_13670	COG3511	phospholipase C
LSG31_13685	COG2271	Major facilitator Superfamily
LSG31_13700	COG0492	ferredoxin-NADP+ reductase activity
LSG31_13710	COG3118	belongs to the thioredoxin family
LSG31_13720	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LSG31_13725	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LSG31_13735	COG0251	oxidation-reduction process
LSG31_13750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LSG31_13755	COG0747	negative chemotaxis
LSG31_13760	COG0601	transmembrane transport
LSG31_13765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LSG31_13770	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_13775	COG0726	polysaccharide deacetylase
LSG31_13780	COG0444	Belongs to the ABC transporter superfamily
LSG31_13785	COG4608	Belongs to the ABC transporter superfamily
LSG31_13790	COG4946	Tricorn protease homolog
LSG31_13790	COG1506	peptidase
LSG31_13790	COG0823	Involved in the tonB-independent uptake of proteins
LSG31_13805	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_13815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LSG31_13825	COG0583	DNA-binding transcription factor activity
LSG31_13840	COG0471	metal ion transport
LSG31_13845	COG0492	ferredoxin-NADP+ reductase activity
LSG31_13855	COG3118	belongs to the thioredoxin family
LSG31_13865	COG1960	acyl-CoA dehydrogenase activity
LSG31_13870	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSG31_13875	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_13890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LSG31_13910	COG0411	ABC transporter
LSG31_13920	COG1960	acyl-CoA dehydrogenase activity
LSG31_13930	COG3290	protein histidine kinase activity
LSG31_13930	COG3829	transcription factor binding
LSG31_13935	COG1024	Enoyl-CoA hydratase
LSG31_13965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LSG31_14005	COG0728	peptidoglycan biosynthetic process
LSG31_14020	COG2199	diguanylate cyclase activity
LSG31_14020	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LSG31_14035	COG3842	ATPase activity
LSG31_14050	COG0583	DNA-binding transcription factor activity
LSG31_14060	COG1752	Esterase of the alpha-beta hydrolase superfamily
LSG31_14120	COG4974	Belongs to the 'phage' integrase family
LSG31_14125	COG0456	acetyltransferase
LSG31_14160	COG1733	regulation of RNA biosynthetic process
LSG31_14165	COG0667	Aldo Keto reductase
LSG31_14170	COG0667	Aldo Keto reductase
LSG31_14200	COG0697	spore germination
LSG31_14215	COG3275	phosphorelay sensor kinase activity
LSG31_14220	COG3279	Response regulator of the LytR AlgR family
LSG31_14230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LSG31_14235	COG0508	dehydrogenase complex catalyzes the overall conversion of
LSG31_14240	COG0567	Dehydrogenase, E1 component
LSG31_14245	COG1653	transport
LSG31_14250	COG1175	transmembrane transport
LSG31_14255	COG0395	ABC-type sugar transport system, permease component
LSG31_14265	COG1501	Belongs to the glycosyl hydrolase 31 family
LSG31_14280	COG2188	Transcriptional regulator
LSG31_14290	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_14300	COG1321	iron dependent repressor
LSG31_14310	COG0302	gtp cyclohydrolase
LSG31_14315	COG0672	)-iron permease
LSG31_14325	COG4122	O-methyltransferase activity
LSG31_14335	COG0726	polysaccharide deacetylase
LSG31_14345	COG0561	phosphatase activity
LSG31_14350	COG3711	transcriptional antiterminator
LSG31_14355	COG1263	PTS System
LSG31_14355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LSG31_14355	COG2190	(PTS) system
LSG31_14360	COG2205	protein histidine kinase activity
LSG31_14375	COG2233	PERMEase
LSG31_14430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LSG31_14430	COG0512	Glutamine amidotransferase of anthranilate synthase
LSG31_14450	COG0667	Aldo Keto reductase
LSG31_14470	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_14520	COG0740	serine-type endopeptidase activity
LSG31_14530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LSG31_14535	COG1104	cysteine desulfurase activity
LSG31_14540	COG0301	tRNA thio-modification
LSG31_14560	COG1671	Belongs to the UPF0178 family
LSG31_14565	COG1217	gtp-binding protein TYPA
LSG31_14580	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_14585	COG0439	Biotin carboxylase
LSG31_14590	COG0511	ligase activity, forming carbon-carbon bonds
LSG31_14595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LSG31_14600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LSG31_14610	COG1733	regulation of RNA biosynthetic process
LSG31_14615	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LSG31_14620	COG2223	nitrite transmembrane transporter activity
LSG31_14625	COG1733	regulation of RNA biosynthetic process
LSG31_14630	COG2001	Belongs to the MraZ family
LSG31_14635	COG0275	rRNA processing
LSG31_14645	COG0768	penicillin binding
LSG31_14650	COG0768	penicillin binding
LSG31_14655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LSG31_14660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LSG31_14675	COG0772	Belongs to the SEDS family
LSG31_14680	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LSG31_14685	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LSG31_14690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LSG31_14710	COG3856	small basic protein
LSG31_14715	COG0849	cell division
LSG31_14720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LSG31_14730	COG1191	sigma factor activity
LSG31_14735	COG1191	sigma factor activity
LSG31_14740	COG1873	PFAM PRC-barrel domain
LSG31_14750	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LSG31_14755	COG1799	cell septum assembly
LSG31_14770	COG3599	regulation of cell shape
LSG31_14775	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LSG31_14795	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LSG31_14800	COG0564	pseudouridine synthase activity
LSG31_14805	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LSG31_14810	COG2233	PERMEase
LSG31_14820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LSG31_14835	COG0543	2 iron, 2 sulfur cluster binding
LSG31_14840	COG0167	dihydroorotate dehydrogenase activity
LSG31_14845	COG0284	orotidine-5'-phosphate decarboxylase activity
LSG31_14850	COG2318	DinB family
LSG31_14875	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LSG31_14880	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LSG31_14885	COG1561	YicC-like family, N-terminal region
LSG31_14890	COG2052	Domain of unknown function (DUF370)
LSG31_14895	COG0194	GDP metabolic process
LSG31_14900	COG1758	RNA polymerase activity
LSG31_14905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LSG31_14910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LSG31_14915	COG0242	peptide deformylase activity
LSG31_14920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LSG31_14925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LSG31_14925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LSG31_14930	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LSG31_14935	COG0631	protein serine/threonine phosphatase activity
LSG31_14940	COG0515	serine threonine protein kinase
LSG31_14940	COG2815	serine threonine protein kinase
LSG31_14945	COG1162	GTPase activity
LSG31_14950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LSG31_14960	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LSG31_14965	COG1302	Protein conserved in bacteria
LSG31_14970	COG1461	Dihydroxyacetone kinase
LSG31_14975	COG1760	l-serine dehydratase
LSG31_14980	COG1760	l-serine dehydratase
LSG31_14985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LSG31_14995	COG0688	phosphatidylethanolamine metabolic process
LSG31_15000	COG0742	ribosomal rna small subunit methyltransferase
LSG31_15005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LSG31_15010	COG1752	Esterase of the alpha-beta hydrolase superfamily
LSG31_15015	COG3480	Lon protease (S16) C-terminal proteolytic domain
LSG31_15020	COG1323	Belongs to the UPF0348 family
LSG31_15030	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LSG31_15035	COG1349	DNA-binding transcription factor activity
LSG31_15035	COG2050	protein possibly involved in aromatic compounds catabolism
LSG31_15040	COG0416	fatty acid biosynthetic process
LSG31_15045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LSG31_15050	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LSG31_15055	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_15060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LSG31_15065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LSG31_15075	COG1196	nuclear chromosome segregation
LSG31_15080	COG0552	protein localization to endoplasmic reticulum
LSG31_15085	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LSG31_15090	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LSG31_15095	COG0228	four-way junction DNA binding
LSG31_15100	COG1837	Belongs to the UPF0109 family
LSG31_15110	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LSG31_15115	COG0336	Belongs to the RNA methyltransferase TrmD family
LSG31_15155	COG2733	membrane
LSG31_15160	COG0561	phosphatase activity
LSG31_15170	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LSG31_15185	COG2171	N-acyltransferase activity
LSG31_15190	COG1473	amidohydrolase
LSG31_15195	COG5609	conserved protein (DUF2294)
LSG31_15200	COG2116	formate transmembrane transporter activity
LSG31_15205	COG3383	formate dehydrogenase (NAD+) activity
LSG31_15220	COG0436	Aminotransferase
LSG31_15225	COG2814	Major facilitator Superfamily
LSG31_15230	COG1657	PFAM Prenyltransferase squalene oxidase
LSG31_15255	COG0095	Lipoate-protein ligase
LSG31_15265	COG0826	peptidase U32
LSG31_15275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LSG31_15285	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LSG31_15300	COG3546	catalase activity
LSG31_15320	COG2259	Doxx family
LSG31_15340	COG0655	NAD(P)H dehydrogenase (quinone) activity
LSG31_15355	COG0697	spore germination
LSG31_15360	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LSG31_15395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LSG31_15410	COG0179	Fumarylacetoacetate (FAA) hydrolase
LSG31_15415	COG2350	Protein conserved in bacteria
LSG31_15420	COG2207	Transcriptional regulator
LSG31_15420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LSG31_15435	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_15440	COG1024	Enoyl-CoA hydratase
LSG31_15485	COG1024	Enoyl-CoA hydratase
LSG31_15490	COG0840	transmembrane signaling receptor activity
LSG31_15495	COG2271	Major facilitator Superfamily
LSG31_15510	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LSG31_15515	COG1760	l-serine dehydratase
LSG31_15520	COG1760	l-serine dehydratase
LSG31_15530	COG0509	glycine decarboxylation via glycine cleavage system
LSG31_15535	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LSG31_15540	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LSG31_15550	COG2860	membrane
LSG31_15555	COG3250	beta-galactosidase activity
LSG31_15560	COG1263	PTS System
LSG31_15560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LSG31_15560	COG2190	(PTS) system
LSG31_15565	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LSG31_15575	COG1904	glucuronate isomerase
LSG31_15585	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_15600	COG0701	Predicted permease
LSG31_15605	COG0701	Predicted permease
LSG31_15610	COG1388	LysM domain
LSG31_15610	COG0791	NLP P60 protein
LSG31_15615	COG1960	acyl-CoA dehydrogenase activity
LSG31_15620	COG0372	Belongs to the citrate synthase family
LSG31_15625	COG2814	Major facilitator Superfamily
LSG31_15630	COG0840	transmembrane signaling receptor activity
LSG31_15635	COG1285	pathogenesis
LSG31_15650	COG1960	acyl-CoA dehydrogenase activity
LSG31_15680	COG1104	cysteine desulfurase activity
LSG31_15685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LSG31_15690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LSG31_15695	COG1827	regulation of RNA biosynthetic process
LSG31_15700	COG2815	serine threonine protein kinase
LSG31_15700	COG0515	serine threonine protein kinase
LSG31_15715	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LSG31_15720	COG0792	nuclease activity
LSG31_15730	COG1183	phosphatidylcholine synthase activity
LSG31_15735	COG0606	chelatase, subunit chli
LSG31_15745	COG0045	succinate-CoA ligase (ADP-forming) activity
LSG31_15750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LSG31_15755	COG0758	DNA mediated transformation
LSG31_15760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LSG31_15765	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LSG31_15770	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LSG31_15775	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LSG31_15780	COG1815	bacterial-type flagellum-dependent cell motility
LSG31_15785	COG1558	bacterial-type flagellum-dependent cell motility
LSG31_15790	COG1677	Flagellar hook-basal body complex protein FliE
LSG31_15795	COG1766	The M ring may be actively involved in energy transduction
LSG31_15800	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LSG31_15810	COG1157	protein secretion by the type III secretion system
LSG31_15830	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LSG31_15840	COG4786	Flagellar basal body rod
LSG31_15845	COG1582	Flagellar protein (FlbD)
LSG31_15855	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LSG31_15860	COG1776	CheC inhibitor of MCP methylation
LSG31_15860	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LSG31_15865	COG2201	protein-glutamate methylesterase activity
LSG31_15875	COG1338	Plays a role in the flagellum-specific transport system
LSG31_15880	COG1987	bacterial-type flagellum assembly
LSG31_15885	COG1684	flagellar biosynthetic protein fliR
LSG31_15890	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LSG31_15895	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LSG31_15900	COG1419	protein localization to endoplasmic reticulum
LSG31_15905	COG0455	bacterial-type flagellum organization
LSG31_15910	COG2201	protein-glutamate methylesterase activity
LSG31_15915	COG0643	Histidine kinase
LSG31_15915	COG2198	Histidine kinase
LSG31_15920	COG0835	chemotaxis
LSG31_15925	COG1776	CheC inhibitor of MCP methylation
LSG31_15930	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
LSG31_15935	COG1191	sigma factor activity
LSG31_15955	COG0052	Belongs to the universal ribosomal protein uS2 family
LSG31_15960	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LSG31_15965	COG0528	UMP kinase activity
LSG31_15970	COG0233	cytoplasmic translational termination
LSG31_15975	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LSG31_15980	COG4589	Belongs to the CDS family
LSG31_15985	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LSG31_15990	COG0779	Required for maturation of 30S ribosomal subunits
LSG31_15995	COG0195	Participates in both transcription termination and antitermination
LSG31_16005	COG1358	cellular component organization or biogenesis
LSG31_16010	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LSG31_16010	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LSG31_16015	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LSG31_16020	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LSG31_16025	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LSG31_16030	COG0196	riboflavin kinase activity
LSG31_16045	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LSG31_16050	COG1185	polyribonucleotide nucleotidyltransferase activity
LSG31_16055	COG0726	polysaccharide deacetylase
LSG31_16060	COG0612	Peptidase, M16
LSG31_16065	COG0756	dUTP diphosphatase activity
LSG31_16070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LSG31_16075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LSG31_16080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LSG31_16085	COG0527	aspartate kinase activity
LSG31_16090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LSG31_16095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LSG31_16100	COG0740	serine-type endopeptidase activity
LSG31_16110	COG1674	ftsk spoiiie
LSG31_16110	COG4980	gas vesicle protein
LSG31_16145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LSG31_16150	COG1058	Belongs to the CinA family
LSG31_16150	COG1546	Belongs to the CinA family
LSG31_16155	COG0513	Belongs to the DEAD box helicase family
LSG31_16160	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LSG31_16165	COG1418	mRNA catabolic process
LSG31_16175	COG1692	metallophosphoesterase
LSG31_16180	COG2359	stage V sporulation protein S
LSG31_16190	COG0613	PHP domain protein
LSG31_16195	COG1234	tRNA 3'-trailer cleavage
LSG31_16205	COG0189	ligase activity
LSG31_16210	COG0189	ligase activity
LSG31_16220	COG0189	ligase activity
LSG31_16230	COG0697	spore germination
LSG31_16245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LSG31_16250	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LSG31_16255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LSG31_16260	COG2136	Putative SAM-dependent methyltransferase
LSG31_16260	COG2521	methyltransferase
LSG31_16270	COG1923	regulation of RNA biosynthetic process
LSG31_16315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LSG31_16325	COG0318	PFAM AMP-dependent synthetase and ligase
LSG31_16340	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LSG31_16355	COG0791	NLP P60 protein
LSG31_16355	COG1388	LysM domain
LSG31_16360	COG0561	phosphatase activity
LSG31_16370	COG0697	spore germination
LSG31_16380	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LSG31_16385	COG2224	Isocitrate lyase
LSG31_16390	COG4109	DRTGG domain
LSG31_16395	COG0492	ferredoxin-NADP+ reductase activity
LSG31_16400	COG0477	Major facilitator Superfamily
LSG31_16410	COG0501	Belongs to the peptidase M48B family
LSG31_16415	COG1045	serine acetyltransferase
LSG31_16425	COG1937	Protein conserved in bacteria
LSG31_16430	COG0542	response to heat
LSG31_16440	COG2068	MobA-Related Protein
LSG31_16455	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LSG31_16465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LSG31_16480	COG1131	(ABC) transporter
LSG31_16505	COG0513	Belongs to the DEAD box helicase family
LSG31_16515	COG1979	alcohol dehydrogenase
LSG31_16530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LSG31_16535	COG0527	aspartate kinase activity
LSG31_16540	COG0768	penicillin binding
LSG31_16560	COG0673	inositol 2-dehydrogenase activity
LSG31_16565	COG2972	Histidine kinase
LSG31_16570	COG2207	Transcriptional regulator
LSG31_16570	COG4753	response regulator
LSG31_16575	COG1653	transport
LSG31_16585	COG2182	Extracellular solute-binding protein
LSG31_16590	COG1175	transmembrane transport
LSG31_16595	COG0395	ABC-type sugar transport system, permease component
LSG31_16610	COG1082	Xylose isomerase domain protein TIM barrel
LSG31_16620	COG4989	oxidoreductase activity
LSG31_16655	COG0492	ferredoxin-NADP+ reductase activity
LSG31_16700	COG1595	DNA-templated transcription, initiation
LSG31_16720	COG0426	domain, Protein
LSG31_16720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LSG31_16725	COG1942	4-Oxalocrotonate Tautomerase
LSG31_16735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LSG31_16770	COG0464	growth
LSG31_16775	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LSG31_16785	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LSG31_16790	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LSG31_16795	COG0789	Transcriptional regulator
LSG31_16800	COG0174	glutamine synthetase
LSG31_16810	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LSG31_16815	COG1247	-acetyltransferase
LSG31_16855	COG1301	dicarboxylic acid transport
LSG31_16875	COG2080	2 iron, 2 sulfur cluster binding
LSG31_16880	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LSG31_16885	COG1612	heme a metabolic process
LSG31_16890	COG4129	membrane
LSG31_16900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LSG31_16920	COG1309	transcriptional regulator
LSG31_16925	COG1064	alcohol dehydrogenase
LSG31_16930	COG2814	Major facilitator Superfamily
LSG31_16935	COG2135	peptidase activity
LSG31_16945	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LSG31_16955	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LSG31_16960	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LSG31_16965	COG1413	lyase activity
LSG31_16970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LSG31_16975	COG0697	spore germination
LSG31_16985	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LSG31_16990	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LSG31_16995	COG0640	Transcriptional regulator
LSG31_17005	COG1879	ABC-type sugar transport system periplasmic component
LSG31_17010	COG1129	ABC transporter
LSG31_17015	COG1172	Belongs to the binding-protein-dependent transport system permease family
LSG31_17020	COG1070	Carbohydrate kinase
LSG31_17025	COG1349	DNA-binding transcription factor activity
LSG31_17030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LSG31_17040	COG1830	Aldolase
LSG31_17075	COG2226	methyltransferase
LSG31_17115	COG0697	spore germination
LSG31_17135	COG1609	Transcriptional regulator
LSG31_17150	COG1175	transmembrane transport
LSG31_17155	COG0395	ABC-type sugar transport system, permease component
LSG31_17160	COG3842	ATPase activity
LSG31_17165	COG0483	inositol monophosphate 1-phosphatase activity
LSG31_17170	COG0584	glycerophosphoryl diester phosphodiesterase
LSG31_17180	COG1902	pentaerythritol trinitrate reductase activity
LSG31_17185	COG1902	pentaerythritol trinitrate reductase activity
LSG31_17190	COG2130	NADP-dependent
LSG31_17200	COG0243	molybdopterin cofactor binding
LSG31_17215	COG2210	Belongs to the sulfur carrier protein TusA family
LSG31_17230	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_17235	COG1024	Enoyl-CoA hydratase
LSG31_17245	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LSG31_17250	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSG31_17260	COG1024	Enoyl-CoA hydratase
LSG31_17265	COG1846	Transcriptional regulator
LSG31_17270	COG2814	Major facilitator Superfamily
LSG31_17275	COG2309	aminopeptidase activity
LSG31_17285	COG0179	Fumarylacetoacetate (FAA) hydrolase
LSG31_17290	COG3119	arylsulfatase activity
LSG31_17295	COG2207	Transcriptional regulator
LSG31_17305	COG0673	inositol 2-dehydrogenase activity
LSG31_17310	COG0673	inositol 2-dehydrogenase activity
LSG31_17315	COG3408	Glycogen debranching enzyme
LSG31_17315	COG3119	arylsulfatase activity
LSG31_17330	COG1175	transmembrane transport
LSG31_17340	COG0395	ABC-type sugar transport system, permease component
LSG31_17345	COG1104	cysteine desulfurase activity
LSG31_17350	COG2188	Transcriptional regulator
LSG31_17360	COG2271	Major facilitator Superfamily
LSG31_17365	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_17370	COG2076	Multidrug Resistance protein
LSG31_17375	COG1378	Sugar-specific transcriptional regulator TrmB
LSG31_17385	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LSG31_17395	COG1999	signal sequence binding
LSG31_17400	COG0277	FAD linked oxidase domain protein
LSG31_17405	COG1024	Enoyl-CoA hydratase
LSG31_17410	COG1960	acyl-CoA dehydrogenase activity
LSG31_17415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LSG31_17435	COG4974	Belongs to the 'phage' integrase family
LSG31_17440	COG1280	lysine exporter protein (LysE YggA)
LSG31_17450	COG3260	NADH ubiquinone oxidoreductase 20
LSG31_17460	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LSG31_17460	COG3261	NADH dehydrogenase
LSG31_17465	COG0651	ATP synthesis coupled electron transport
LSG31_17475	COG0650	Formate hydrogenlyase subunit 4
LSG31_17480	COG0651	ATP synthesis coupled electron transport
LSG31_17485	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LSG31_17505	COG5337	Spore coat protein CotH
LSG31_17525	COG5002	protein histidine kinase activity
LSG31_17540	COG1396	sequence-specific DNA binding
LSG31_17550	COG0488	(ABC) transporter
LSG31_17555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LSG31_17560	COG3973	AAA domain
LSG31_17565	COG4974	Belongs to the 'phage' integrase family
LSG31_17570	COG0366	Alpha amylase catalytic
LSG31_17575	COG0366	Alpha amylase catalytic
LSG31_17590	COG1653	transport
LSG31_17600	COG3935	DnaD domain protein
LSG31_17605	COG0017	Asparaginyl-tRNA synthetase
LSG31_17610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LSG31_17630	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LSG31_17640	COG0402	S-adenosylhomocysteine deaminase activity
LSG31_17645	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LSG31_17650	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LSG31_17655	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LSG31_17660	COG1199	ATP-dependent helicase activity
LSG31_17660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LSG31_17670	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LSG31_17675	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LSG31_17680	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LSG31_17685	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LSG31_17685	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LSG31_17690	COG0617	tRNA 3'-terminal CCA addition
LSG31_17695	COG0438	transferase activity, transferring glycosyl groups
LSG31_17700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LSG31_17710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LSG31_17715	COG1694	Mazg nucleotide pyrophosphohydrolase
LSG31_17720	COG3314	Sporulation integral membrane protein YlbJ
LSG31_17725	COG1968	undecaprenyl-diphosphatase activity
LSG31_17730	COG3949	Membrane
LSG31_17735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LSG31_17740	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LSG31_17740	COG2010	Cytochrome c
LSG31_17745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LSG31_17760	COG5582	Belongs to the UPF0302 family
LSG31_17775	COG0287	Prephenate dehydrogenase
LSG31_17780	COG0159	tryptophan synthase activity
LSG31_17790	COG0135	phosphoribosylanthranilate isomerase activity
LSG31_17795	COG0134	indole-3-glycerol-phosphate synthase activity
LSG31_17800	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LSG31_17805	COG4401	Chorismate mutase type I
LSG31_17810	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LSG31_17815	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LSG31_17820	COG1363	Peptidase, m42
LSG31_17840	COG0564	pseudouridine synthase activity
LSG31_17845	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LSG31_17850	COG1752	Esterase of the alpha-beta hydrolase superfamily
LSG31_17855	COG0058	SHG alpha-glucan phosphorylase activity
LSG31_17860	COG0297	glycogen (starch) synthase activity
LSG31_17865	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LSG31_17870	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LSG31_17875	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LSG31_17880	COG0105	UTP biosynthetic process
LSG31_17890	COG0142	geranyltranstransferase activity
LSG31_17905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LSG31_17915	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LSG31_17920	COG0095	Lipoate-protein ligase
LSG31_17925	COG0509	glycine decarboxylation via glycine cleavage system
LSG31_17930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LSG31_17935	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LSG31_17940	COG1160	GTP binding
LSG31_17955	COG1304	FMN binding
LSG31_17960	COG0539	negative regulation of cytoplasmic translation
LSG31_17965	COG0204	Acyl-transferase
LSG31_17970	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LSG31_17985	COG2959	enzyme of heme biosynthesis
LSG31_17995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LSG31_18005	COG0626	cystathionine gamma-synthase activity
LSG31_18015	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LSG31_18020	COG1809	phosphosulfolactate synthase activity
LSG31_18025	COG2707	UPF0756 membrane protein
LSG31_18035	COG1609	Transcriptional regulator
LSG31_18075	COG0210	DNA helicase
LSG31_18095	COG0302	gtp cyclohydrolase
LSG31_18105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LSG31_18110	COG2226	methyltransferase
LSG31_18120	COG0791	NLP P60 protein
LSG31_18125	COG0070	glutamate synthase
LSG31_18125	COG0069	glutamate synthase activity
LSG31_18125	COG0067	glutamate synthase
LSG31_18130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LSG31_18145	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LSG31_18150	COG1242	4 iron, 4 sulfur cluster binding
LSG31_18155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LSG31_18170	COG4844	belongs to the
LSG31_18180	COG2339	peptidase activity
LSG31_18240	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LSG31_18295	COG0406	alpha-ribazole phosphatase activity
LSG31_18300	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LSG31_18310	COG0588	phosphoglycerate mutase activity
LSG31_18315	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LSG31_18325	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LSG31_18330	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LSG31_18335	COG1492	cobalamin metabolic process
LSG31_18340	COG5002	protein histidine kinase activity
LSG31_18350	COG3459	Glycosyltransferase 36 associated
LSG31_18370	COG0246	Mannitol dehydrogenase
LSG31_18380	COG3711	transcriptional antiterminator
LSG31_18390	COG0697	spore germination
LSG31_18395	COG1132	(ABC) transporter
LSG31_18400	COG0243	molybdopterin cofactor binding
LSG31_18405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LSG31_18410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LSG31_18425	COG0109	protoheme IX farnesyltransferase activity
LSG31_18450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LSG31_18465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LSG31_18470	COG1113	amino acid transport
LSG31_18475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LSG31_18480	COG4869	propanediol catabolic process
LSG31_18490	COG2188	Transcriptional regulator
LSG31_18495	COG1349	DNA-binding transcription factor activity
LSG31_18500	COG1070	Carbohydrate kinase
LSG31_18505	COG4952	isomerase
LSG31_18510	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_18510	COG3347	Dehydrogenase
LSG31_18520	COG3711	transcriptional antiterminator
LSG31_18530	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LSG31_18540	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LSG31_18585	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LSG31_18590	COG3547	Transposase (IS116 IS110 IS902 family)
LSG31_18600	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LSG31_18605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LSG31_18610	COG1476	TRANSCRIPTIONal
LSG31_18615	COG2022	thiamine diphosphate biosynthetic process
LSG31_18625	COG1832	CoA-binding protein
LSG31_18630	COG5002	protein histidine kinase activity
LSG31_18635	COG0745	RESPONSE REGULATOR receiver
LSG31_18640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LSG31_18645	COG1333	cytochrome c biogenesis protein
LSG31_18655	COG1187	pseudouridine synthase activity
LSG31_18660	COG0700	Nucleoside recognition
LSG31_18665	COG2715	membrane protein required for spore maturation
LSG31_18670	COG1686	Belongs to the peptidase S11 family
LSG31_18675	COG3874	Sporulation protein YtfJ
LSG31_18685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LSG31_18690	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LSG31_18695	COG1994	Peptidase M50
LSG31_18700	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LSG31_18705	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LSG31_18705	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LSG31_18715	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LSG31_18715	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LSG31_18720	COG1686	Belongs to the peptidase S11 family
LSG31_18725	COG0019	diaminopimelate decarboxylase activity
LSG31_18740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LSG31_18750	COG1191	sigma factor activity
LSG31_18755	COG2172	sigma factor antagonist activity
LSG31_18760	COG1366	Belongs to the anti-sigma-factor antagonist family
LSG31_18770	COG1686	Belongs to the peptidase S11 family
LSG31_18790	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LSG31_18800	COG4974	Belongs to the 'phage' integrase family
LSG31_18810	COG0735	belongs to the Fur family
LSG31_18820	COG1300	Membrane
LSG31_18825	COG1379	DNA repair
LSG31_18830	COG0494	nUDIX hydrolase
LSG31_18840	COG1113	amino acid transport
LSG31_18845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LSG31_18850	COG0346	lactoylglutathione lyase activity
LSG31_18855	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LSG31_18855	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LSG31_18865	COG0004	ammonium transporteR
LSG31_18870	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LSG31_18875	COG0508	dehydrogenase complex catalyzes the overall conversion of
LSG31_18880	COG0022	dehydrogenase e1 component
LSG31_18885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LSG31_18890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LSG31_18895	COG3829	transcription factor binding
LSG31_18895	COG3290	protein histidine kinase activity
LSG31_18915	COG0463	Glycosyl transferase, family 2
LSG31_18930	COG0315	cyclic pyranopterin monophosphate synthase activity
LSG31_18940	COG0314	molybdopterin synthase activity
LSG31_18945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LSG31_18960	COG0006	proline dipeptidase activity
LSG31_18980	COG1131	(ABC) transporter
LSG31_19000	COG3547	Transposase (IS116 IS110 IS902 family)
LSG31_19005	COG0477	Major facilitator Superfamily
LSG31_19010	COG0531	amino acid
LSG31_19015	COG2205	protein histidine kinase activity
LSG31_19020	COG2172	sigma factor antagonist activity
LSG31_19025	COG1164	Oligoendopeptidase f
LSG31_19035	COG0179	Fumarylacetoacetate (FAA) hydrolase
LSG31_19050	COG0129	dihydroxy-acid dehydratase activity
LSG31_19060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LSG31_19065	COG2084	Dehydrogenase
LSG31_19070	COG1388	LysM domain
LSG31_19070	COG3584	3D domain protein
LSG31_19075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LSG31_19080	COG0109	protoheme IX farnesyltransferase activity
LSG31_19085	COG1392	Phosphate transport regulator
LSG31_19090	COG0306	phosphate transporter
LSG31_19100	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LSG31_19110	COG0318	PFAM AMP-dependent synthetase and ligase
LSG31_19115	COG0482	sulfurtransferase activity
LSG31_19120	COG2363	Small membrane protein
LSG31_19145	COG0475	glutathione-regulated potassium exporter activity
LSG31_19145	COG0569	domain protein
LSG31_19170	COG0492	ferredoxin-NADP+ reductase activity
LSG31_19200	COG1122	ATPase activity
LSG31_19205	COG1122	ATPase activity
LSG31_19210	COG1268	BioY protein
LSG31_19215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LSG31_19220	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LSG31_19220	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LSG31_19230	COG0039	L-malate dehydrogenase activity
LSG31_19235	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LSG31_19245	COG1233	COG1233 Phytoene dehydrogenase and related
LSG31_19250	COG0531	amino acid
LSG31_19255	COG0604	alcohol dehydrogenase
LSG31_19270	COG3279	Response regulator of the LytR AlgR family
LSG31_19275	COG3275	phosphorelay sensor kinase activity
LSG31_19280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LSG31_19290	COG1584	GPR1 FUN34 yaaH family protein
LSG31_19295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LSG31_19315	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_19320	COG0735	belongs to the Fur family
LSG31_19325	COG3547	Transposase (IS116 IS110 IS902 family)
LSG31_19335	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LSG31_19345	COG0697	spore germination
LSG31_19370	COG2808	Putative FMN-binding domain
LSG31_19385	COG1396	sequence-specific DNA binding
LSG31_19400	COG0280	phosphate acetyltransferase
LSG31_19420	COG3547	Transposase (IS116 IS110 IS902 family)
LSG31_19440	COG0697	spore germination
LSG31_19445	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LSG31_19455	COG0697	spore germination
LSG31_19490	COG2217	Heavy metal translocating P-type atpase
LSG31_19495	COG1937	Protein conserved in bacteria
LSG31_19500	COG0477	Major facilitator Superfamily
LSG31_19525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LSG31_19530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LSG31_19535	COG0640	Transcriptional regulator
LSG31_19550	COG0531	amino acid
LSG31_19570	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_19580	COG2226	methyltransferase
LSG31_19605	COG2249	NAD(P)H dehydrogenase (quinone) activity
LSG31_19610	COG1309	transcriptional regulator
LSG31_19615	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LSG31_19620	COG2169	Transcriptional regulator
LSG31_19625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LSG31_19645	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_19665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LSG31_19690	COG0077	Prephenate dehydratase
LSG31_19700	COG1448	Aminotransferase
LSG31_19710	COG0066	3-isopropylmalate dehydratase activity
LSG31_19715	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LSG31_19735	COG1335	isochorismatase
LSG31_19740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LSG31_19795	COG0582	viral genome integration into host DNA
LSG31_19810	COG1024	Enoyl-CoA hydratase
LSG31_19860	COG0745	RESPONSE REGULATOR receiver
LSG31_19865	COG0750	zinc metalloprotease
LSG31_19870	COG0497	DNA recombination
LSG31_19880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LSG31_19890	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LSG31_19895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LSG31_19900	COG2323	membrane
LSG31_19915	COG1722	exodeoxyribonuclease VII activity
LSG31_19925	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LSG31_19940	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LSG31_19945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LSG31_19960	COG1302	Protein conserved in bacteria
LSG31_19965	COG0439	Biotin carboxylase
LSG31_19970	COG0511	ligase activity, forming carbon-carbon bonds
LSG31_20010	COG3854	ATPases associated with a variety of cellular activities
LSG31_20030	COG0531	amino acid
LSG31_20035	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LSG31_20040	COG0006	proline dipeptidase activity
LSG31_20050	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LSG31_20055	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LSG31_20060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LSG31_20065	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LSG31_20080	COG0083	homoserine kinase activity
LSG31_20085	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LSG31_20090	COG4492	Belongs to the UPF0735 family
LSG31_20095	COG0367	asparagine synthase
LSG31_20120	COG4537	Required for transformation and DNA binding
LSG31_20140	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LSG31_20150	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LSG31_20160	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LSG31_20165	COG1530	ribonuclease E activity
LSG31_20180	COG2894	cell division
LSG31_20185	COG0850	regulation of cytokinetic process
LSG31_20200	COG1077	Cell shape determining protein MreB Mrl
LSG31_20205	COG2003	Belongs to the UPF0758 family
LSG31_20210	COG0424	maF-like protein
LSG31_20225	COG3583	domain protein
LSG31_20225	COG3584	3D domain protein
LSG31_20260	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LSG31_20270	COG1459	type II secretion system
LSG31_20280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LSG31_20285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LSG31_20290	COG0285	dihydrofolate synthase activity
LSG31_20325	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LSG31_20330	COG0113	porphobilinogen synthase activity
LSG31_20340	COG0181	hydroxymethylbilane synthase activity
LSG31_20345	COG1648	precorrin-2 dehydrogenase activity
LSG31_20345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LSG31_20350	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LSG31_20355	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LSG31_20365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LSG31_20375	COG1067	ATP-dependent peptidase activity
LSG31_20375	COG0470	DNA polymerase III
LSG31_20380	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LSG31_20385	COG0740	serine-type endopeptidase activity
LSG31_20390	COG0544	peptidyl-prolyl cis-trans isomerase activity
LSG31_20400	COG0438	transferase activity, transferring glycosyl groups
LSG31_20410	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_20430	COG0438	transferase activity, transferring glycosyl groups
LSG31_20435	COG1216	Glycosyl transferase, family 2
LSG31_20460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LSG31_20465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LSG31_20470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LSG31_20470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LSG31_20485	COG0582	viral genome integration into host DNA
LSG31_20500	COG0622	Phosphoesterase
LSG31_20510	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LSG31_20525	COG1846	Transcriptional regulator
LSG31_20535	COG1278	Cold shock
LSG31_20565	COG0514	ATP-dependent DNA helicase (RecQ)
LSG31_20570	COG2197	response regulator
LSG31_20575	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LSG31_20580	COG1053	succinate dehydrogenase
LSG31_20585	COG2009	succinate dehydrogenase
LSG31_20595	COG2188	Transcriptional regulator
LSG31_20600	COG0366	Alpha amylase catalytic
LSG31_20605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LSG31_20605	COG1263	PTS System
LSG31_20610	COG0840	transmembrane signaling receptor activity
LSG31_20615	COG0322	excinuclease ABC activity
LSG31_20620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LSG31_20625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LSG31_20630	COG0454	-acetyltransferase
LSG31_20635	COG0123	including yeast histone deacetylase and acetoin utilization protein
LSG31_20640	COG0318	PFAM AMP-dependent synthetase and ligase
LSG31_20645	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LSG31_20650	COG0596	Alpha beta hydrolase
LSG31_20655	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LSG31_20660	COG1169	isochorismate synthase
LSG31_20665	COG1575	Belongs to the MenA family. Type 1 subfamily
LSG31_20670	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LSG31_20670	COG1605	Chorismate mutase
LSG31_20675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LSG31_20685	COG0741	lytic transglycosylase activity
LSG31_20690	COG0387	Pfam Sodium calcium exchanger
LSG31_20695	COG1253	flavin adenine dinucleotide binding
LSG31_20715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LSG31_20725	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LSG31_20730	COG1376	ErfK ybiS ycfS ynhG family protein
LSG31_20735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LSG31_20740	COG0010	Belongs to the arginase family
LSG31_20755	COG5263	repeat protein
LSG31_20755	COG4193	domain, Protein
LSG31_20760	COG1876	peptidase activity
LSG31_20765	COG0542	response to heat
LSG31_20770	COG1414	Transcriptional regulator
LSG31_20780	COG0028	Belongs to the TPP enzyme family
LSG31_20790	COG3958	Transketolase
LSG31_20795	COG3959	Transketolase, thiamine diphosphate binding domain
LSG31_20800	COG0277	FAD linked oxidase domain protein
LSG31_20805	COG0247	lactate metabolic process
LSG31_20810	COG0277	FAD linked oxidase domain protein
LSG31_20815	COG1620	l-lactate permease
LSG31_20820	COG2508	Transcriptional regulator
LSG31_20820	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LSG31_20825	COG0686	Belongs to the AlaDH PNT family
LSG31_20840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LSG31_20845	COG0004	ammonium transporteR
LSG31_20850	COG2226	methyltransferase
LSG31_20855	COG2814	Major facilitator Superfamily
LSG31_20865	COG0586	Pfam SNARE associated Golgi protein
LSG31_20880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LSG31_20885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LSG31_20895	COG2186	Transcriptional regulator
LSG31_20900	COG2271	Major facilitator Superfamily
LSG31_20920	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSG31_20925	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_20930	COG2271	Major facilitator Superfamily
LSG31_20935	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LSG31_20940	COG1609	Transcriptional regulator
LSG31_20950	COG1454	alcohol dehydrogenase
LSG31_20975	COG0800	Aldolase
LSG31_20980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LSG31_20985	COG2721	sulfolactate sulfo-lyase activity
LSG31_20990	COG0246	Mannitol dehydrogenase
LSG31_20995	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LSG31_20995	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LSG31_21005	COG1609	Transcriptional regulator
LSG31_21015	COG0534	Mate efflux family protein
LSG31_21020	COG1609	Transcriptional regulator
LSG31_21025	COG1904	glucuronate isomerase
LSG31_21035	COG1252	NADH dehydrogenase
LSG31_21040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LSG31_21045	COG0187	DNA topoisomerase II activity
LSG31_21050	COG1309	transcriptional regulator
LSG31_21055	COG0842	Transport permease protein
LSG31_21060	COG1131	(ABC) transporter
LSG31_21065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LSG31_21105	COG2271	Major facilitator Superfamily
LSG31_21110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LSG31_21115	COG0384	phenazine biosynthesis protein PhzF
LSG31_21125	COG1077	Cell shape determining protein MreB Mrl
LSG31_21140	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_21145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LSG31_21150	COG3962	Belongs to the TPP enzyme family
LSG31_21160	COG0673	inositol 2-dehydrogenase activity
LSG31_21170	COG0191	fructose-bisphosphate aldolase activity
LSG31_21175	COG1082	Xylose isomerase domain protein TIM barrel
LSG31_21180	COG1082	Xylose isomerase domain protein TIM barrel
LSG31_21185	COG0673	inositol 2-dehydrogenase activity
LSG31_21190	COG1082	Xylose isomerase domain protein TIM barrel
LSG31_21195	COG3718	enzyme involved in inositol metabolism
LSG31_21200	COG0673	inositol 2-dehydrogenase activity
LSG31_21210	COG1129	ABC transporter
LSG31_21215	COG1172	Belongs to the binding-protein-dependent transport system permease family
LSG31_21220	COG0840	transmembrane signaling receptor activity
LSG31_21225	COG1609	Transcriptional regulator
LSG31_21230	COG1172	Belongs to the binding-protein-dependent transport system permease family
LSG31_21235	COG1129	ABC transporter
LSG31_21240	COG0673	inositol 2-dehydrogenase activity
LSG31_21255	COG1082	Xylose isomerase domain protein TIM barrel
LSG31_21260	COG0673	inositol 2-dehydrogenase activity
LSG31_21265	COG1609	Transcriptional regulator
LSG31_21270	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LSG31_21275	COG0116	Belongs to the methyltransferase superfamily
LSG31_21280	COG3619	membrane
LSG31_21295	COG2871	sodium ion transport
LSG31_21320	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
LSG31_21340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LSG31_21360	COG5002	protein histidine kinase activity
LSG31_21370	COG2186	Transcriptional regulator
LSG31_21375	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_21380	COG3958	Transketolase
LSG31_21385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LSG31_21415	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LSG31_21420	COG0647	UMP catabolic process
LSG31_21425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LSG31_21440	COG2814	Major facilitator Superfamily
LSG31_21450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LSG31_21465	COG3730	PTS system glucitol sorbitol-specific
LSG31_21470	COG3732	PTS system glucitol sorbitol-specific
LSG31_21490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LSG31_21495	COG0508	dehydrogenase complex catalyzes the overall conversion of
LSG31_21500	COG0022	dehydrogenase e1 component
LSG31_21505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LSG31_21510	COG3775	system Galactitol-specific IIC component
LSG31_21515	COG3414	Phosphotransferase system galactitol-specific IIB component
LSG31_21530	COG1070	Carbohydrate kinase
LSG31_21535	COG0588	phosphoglycerate mutase activity
LSG31_21540	COG1070	Carbohydrate kinase
LSG31_21555	COG1070	Carbohydrate kinase
LSG31_21565	COG2376	Dihydroxyacetone kinase
LSG31_21570	COG0698	ribose 5-phosphate isomerase
LSG31_21575	COG1063	alcohol dehydrogenase
LSG31_21580	COG1063	alcohol dehydrogenase
LSG31_21585	COG1879	ABC-type sugar transport system periplasmic component
LSG31_21590	COG1172	Belongs to the binding-protein-dependent transport system permease family
LSG31_21595	COG1129	ABC transporter
LSG31_21610	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_21615	COG1349	DNA-binding transcription factor activity
LSG31_21620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LSG31_21630	COG1070	Carbohydrate kinase
LSG31_21635	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_21650	COG2205	protein histidine kinase activity
LSG31_21660	COG3584	3D domain protein
LSG31_21670	COG0352	thiamine-phosphate diphosphorylase activity
LSG31_21675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LSG31_21680	COG1725	Transcriptional regulator
LSG31_21685	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LSG31_21685	COG0674	pyruvate-flavodoxin oxidoreductase activity
LSG31_21690	COG1013	pyruvate-flavodoxin oxidoreductase activity
LSG31_21700	COG0492	ferredoxin-NADP+ reductase activity
LSG31_21710	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LSG31_21720	COG3377	Domain of unknown function (DUF1805)
LSG31_21725	COG1215	transferase activity, transferring glycosyl groups
LSG31_21730	COG1078	dGTPase activity
LSG31_21740	COG0316	Belongs to the HesB IscA family
LSG31_21745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LSG31_21755	COG0438	transferase activity, transferring glycosyl groups
LSG31_21760	COG1982	Orn Lys Arg decarboxylase major
LSG31_21780	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LSG31_21785	COG0235	Class ii aldolase
LSG31_21790	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LSG31_21795	COG1850	ribulose-bisphosphate carboxylase activity
LSG31_21800	COG0436	Aminotransferase
LSG31_21810	COG0288	reversible hydration of carbon dioxide
LSG31_21820	COG3290	protein histidine kinase activity
LSG31_21825	COG4565	transcriptional regulatory protein
LSG31_21830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LSG31_21835	COG0174	glutamine synthetase
LSG31_21840	COG0772	Belongs to the SEDS family
LSG31_21850	COG5002	protein histidine kinase activity
LSG31_21855	COG0772	Belongs to the SEDS family
LSG31_21870	COG1696	Membrane protein involved in D-alanine export
LSG31_21875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LSG31_21885	COG5002	protein histidine kinase activity
LSG31_21890	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LSG31_21890	COG3321	synthase
LSG31_21890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LSG31_21895	COG1213	nucleotidyl transferase
LSG31_21900	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LSG31_21900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LSG31_21920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LSG31_21935	COG0720	synthase
LSG31_21940	COG0602	queuosine metabolic process
LSG31_21955	COG0612	Peptidase, M16
LSG31_21960	COG0612	Peptidase, M16
LSG31_21980	COG1252	NADH dehydrogenase
LSG31_21985	COG0583	DNA-binding transcription factor activity
LSG31_22010	COG1968	undecaprenyl-diphosphatase activity
LSG31_22015	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LSG31_22015	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LSG31_22015	COG1703	isobutyryl-CoA mutase activity
LSG31_22020	COG0281	malic enzyme
LSG31_22025	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LSG31_22030	COG2340	Cysteine-rich secretory protein family
LSG31_22075	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LSG31_22080	COG3584	3D domain protein
LSG31_22085	COG1960	acyl-CoA dehydrogenase activity
LSG31_22090	COG0183	Belongs to the thiolase family
LSG31_22095	COG1024	Enoyl-CoA hydratase
LSG31_22095	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSG31_22100	COG0537	adenosine 5'-monophosphoramidase activity
LSG31_22120	COG0133	tryptophan synthase activity
LSG31_22125	COG2084	Dehydrogenase
LSG31_22150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LSG31_22180	COG1181	Belongs to the D-alanine--D-alanine ligase family
LSG31_22185	COG0747	negative chemotaxis
LSG31_22190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LSG31_22195	COG0601	transmembrane transport
LSG31_22200	COG4608	Belongs to the ABC transporter superfamily
LSG31_22210	COG0564	pseudouridine synthase activity
LSG31_22215	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LSG31_22220	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LSG31_22220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LSG31_22235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LSG31_22245	COG4149	molybdate abc transporter
LSG31_22250	COG0725	ABC transporter, periplasmic molybdate-binding protein
LSG31_22255	COG1910	domain protein
LSG31_22265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LSG31_22280	COG1086	Polysaccharide biosynthesis protein
LSG31_22290	COG0438	transferase activity, transferring glycosyl groups
LSG31_22330	COG0529	Catalyzes the synthesis of activated sulfate
LSG31_22345	COG0644	oxidoreductase
LSG31_22350	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LSG31_22370	COG2244	polysaccharide biosynthetic process
LSG31_22375	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LSG31_22380	COG2086	electron transfer activity
LSG31_22400	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LSG31_22400	COG0646	methionine synthase
LSG31_22420	COG0372	Belongs to the citrate synthase family
LSG31_22425	COG2346	COG2346, Truncated hemoglobins
LSG31_22430	COG0824	Thioesterase
LSG31_22445	COG0735	belongs to the Fur family
LSG31_22465	COG0583	DNA-binding transcription factor activity
LSG31_22470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LSG31_22475	COG0066	3-isopropylmalate dehydratase activity
LSG31_22480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LSG31_22485	COG0166	Belongs to the GPI family
LSG31_22490	COG1482	cell wall glycoprotein biosynthetic process
LSG31_22500	COG0420	3'-5' exonuclease activity
LSG31_22520	COG1543	Belongs to the glycosyl hydrolase 57 family
LSG31_22535	COG0464	growth
LSG31_22570	COG0673	inositol 2-dehydrogenase activity
LSG31_22575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LSG31_22580	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_22585	COG1312	Catalyzes the dehydration of D-mannonate
LSG31_22590	COG4149	molybdate abc transporter
LSG31_22595	COG1176	ABC-type spermidine putrescine transport system, permease component I
LSG31_22600	COG3842	ATPase activity
LSG31_22610	COG4753	response regulator
LSG31_22610	COG2207	Transcriptional regulator
LSG31_22615	COG2972	Histidine kinase
LSG31_22620	COG1819	glycosyl
LSG31_22630	COG0640	Transcriptional regulator
LSG31_22635	COG3177	Filamentation induced by cAMP protein fic
LSG31_22655	COG1203	CRISPR-associated helicase, Cas3
LSG31_22680	COG0840	transmembrane signaling receptor activity
LSG31_22705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LSG31_22710	COG0477	Major facilitator Superfamily
LSG31_22720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LSG31_22725	COG1063	alcohol dehydrogenase
LSG31_22740	COG0360	Binds together with S18 to 16S ribosomal RNA
LSG31_22745	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LSG31_22750	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LSG31_22760	COG4632	Exopolysaccharide biosynthesis protein
LSG31_22760	COG5434	Belongs to the glycosyl hydrolase 28 family
LSG31_22770	COG0531	amino acid
LSG31_22775	COG0531	amino acid
LSG31_22795	COG0788	formyltetrahydrofolate deformylase activity
LSG31_22800	COG0791	NLP P60 protein
LSG31_22805	COG4846	Membrane protein involved in cytochrome C biogenesis
LSG31_22810	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LSG31_22825	COG0367	asparagine synthase
LSG31_22835	COG4948	Mandelate Racemase Muconate Lactonizing
LSG31_22850	COG2182	Extracellular solute-binding protein
LSG31_22855	COG1175	transmembrane transport
LSG31_22860	COG0395	ABC-type sugar transport system, permease component
LSG31_22865	COG3250	beta-galactosidase activity
LSG31_22870	COG1172	Belongs to the binding-protein-dependent transport system permease family
LSG31_22875	COG1172	Belongs to the binding-protein-dependent transport system permease family
LSG31_22880	COG1129	ABC transporter
LSG31_22885	COG1879	ABC-type sugar transport system periplasmic component
LSG31_22895	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_22900	COG1414	Transcriptional regulator
LSG31_22905	COG0800	Aldolase
LSG31_22915	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_22920	COG1063	alcohol dehydrogenase
LSG31_22925	COG4948	Mandelate Racemase Muconate Lactonizing
LSG31_22930	COG1414	Transcriptional regulator
LSG31_22935	COG1012	belongs to the aldehyde dehydrogenase family
LSG31_22940	COG0506	proline dehydrogenase activity
LSG31_22945	COG3829	transcription factor binding
LSG31_22945	COG3290	protein histidine kinase activity
LSG31_22950	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LSG31_22955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LSG31_22960	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LSG31_22965	COG0306	phosphate transporter
LSG31_22990	COG1151	hydroxylamine reductase activity
LSG31_23000	COG1028	Short-chain dehydrogenase reductase Sdr
LSG31_23005	COG1054	Belongs to the UPF0176 family
LSG31_23010	COG1914	H( )-stimulated, divalent metal cation uptake system
LSG31_23020	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LSG31_23025	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LSG31_23030	COG0697	spore germination
LSG31_23035	COG2267	carboxylic ester hydrolase activity
LSG31_23040	COG1234	tRNA 3'-trailer cleavage
LSG31_23050	COG0519	Catalyzes the synthesis of GMP from XMP
LSG31_23055	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LSG31_23075	COG2226	methyltransferase
LSG31_23085	COG1607	acyl-coa hydrolase
LSG31_23095	COG0671	phosphoesterase, PA-phosphatase related