locus-tag	class	description
TC41_0003	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TC41_0005	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
TC41_0006	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TC41_0007	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TC41_0014	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TC41_0015	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
TC41_0016	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
TC41_0028	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TC41_0032	ENOG4108IJ1	Dehydrogenase
TC41_0044	ENOG4108JQ9	ABC transporter
TC41_0045	ENOG4105DIH	basic membrane
TC41_0048	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
TC41_0049	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TC41_0051	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TC41_0056	ENOG4105CPC	Aldo Keto reductase
TC41_0058	ENOG4105CF7	AraC family transcriptional regulator
TC41_0059	ENOG4105EFI	regulatoR
TC41_0060	ENOG4105BZU	Histidine kinase
TC41_0062	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
TC41_0066	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
TC41_0067	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TC41_0068	ENOG4107TXC	Transcriptional regulator
TC41_0069	ENOG4105DEF	Extracellular solute-binding protein, family 5
TC41_0071	ENOG4107GRR	phosphate transport regulator
TC41_0072	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
TC41_0073	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
TC41_0075	ENOG4105G3Z	GntR family transcriptional regulator
TC41_0076	ENOG4105CHR	reductase
TC41_0081	ENOG4105BZU	Histidine kinase
TC41_0083	ENOG4105ME7	Membrane
TC41_0084	ENOG4105CKK	Glycosyl transferase, family 2
TC41_0085	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
TC41_0088	ENOG4105CHR	reductase
TC41_0089	ENOG4107104	thymidine kinase
TC41_0092	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
TC41_0093	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TC41_0094	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
TC41_0096	ENOG4105DRS	transport system, permease
TC41_0099	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
TC41_0100	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
TC41_0102	ENOG4105ECB	domain protein
TC41_0103	ENOG4105EEM	helicase
TC41_0104	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TC41_0106	ENOG4105DKQ	ROK family
TC41_0112	ENOG4105EYF	MMPL domain protein
TC41_0115	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
TC41_0117	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
TC41_0119	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
TC41_0120	ENOG4107V49	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
TC41_0124	ENOG4105CAQ	asparagine synthetase
TC41_0126	ENOG4108Z6B	deaminase
TC41_0127	ENOG4105BZU	Histidine kinase
TC41_0129	ENOG4105C6E	dna polymerase iii
TC41_0130	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
TC41_0131	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
TC41_0132	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
TC41_0137	ENOG4108S8N	class II Aldolase
TC41_0139	ENOG4107TPS	domain protein
TC41_0142	ENOG4105C8Q	Methyl-accepting chemotaxis
TC41_0143	ENOG4107YTP	response regulator receiver protein
TC41_0145	ENOG4106YBV	Methyl-accepting chemotaxis
TC41_0146	ENOG4105CBS	Chea signal transduction histidine kinase
TC41_0147	ENOG4108V3W	Chemotaxis protein, CheW
TC41_0148	ENOG4108N3W	hemolysin secretion protein
TC41_0150	ENOG4105E5H	Transposase
TC41_0151	ENOG4105E5H	Transposase
TC41_0155	ENOG41067KS	pro-sigma K processing
TC41_0159	ENOG4105CXN	decarboxylase
TC41_0160	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TC41_0161	ENOG4105X0R	protein from nitrogen regulatory protein P-II
TC41_0162	ENOG4107QRG	dna polymerase iii
TC41_0163	ENOG4105MA4	psp1 domain protein
TC41_0164	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
TC41_0166	ENOG4105KRN	Transcriptional regulator, abrb family
TC41_0169	ENOG4105F8V	Hydrolase, tatD family
TC41_0171	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TC41_0173	ENOG4108CCU	Ribonucleotide-diphosphate reductase subunit beta
TC41_0179	ENOG4107WYG	Transcriptional regulator, luxr family
TC41_0182	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_0183	ENOG4105C1G	acyl-Coa dehydrogenase
TC41_0184	ENOG4105C1G	acyl-Coa dehydrogenase
TC41_0185	ENOG4105E39	Enoyl-CoA hydratase
TC41_0186	ENOG4105CHR	reductase
TC41_0187	ENOG4105CHU	acetyl-coa acetyltransferase
TC41_0191	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
TC41_0193	ENOG4105C26	Dehydrogenase
TC41_0194	ENOG4105C0A	alcohol dehydrogenase
TC41_0200	ENOG4105CHR	reductase
TC41_0201	ENOG4105C1G	acyl-Coa dehydrogenase
TC41_0202	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_0203	ENOG410900P	UPF0336 protein
TC41_0220	ENOG4108ETV	ABC transporter
TC41_0235	ENOG4105XFA	sporulation peptidase YabG
TC41_0237	ENOG4105W42	Veg protein
TC41_0240	ENOG4107RRY	Cyanophycin synthetase
TC41_0241	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
TC41_0242	ENOG4105DFT	pur operon repressor
TC41_0243	ENOG4105KME	endoribonuclease L-psp
TC41_0244	ENOG4105K4W	Could be involved in septation (By similarity)
TC41_0245	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
TC41_0246	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TC41_0247	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
TC41_0249	ENOG4108JA2	transcriptioN-repair coupling factor
TC41_0250	ENOG4108IY2	MazG family
TC41_0252	ENOG41082I2	s4 domain protein
TC41_0256	ENOG41060GV	RNA binding s1 domain protein
TC41_0259	ENOG4108UK2	deaminase
TC41_0264	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
TC41_0265	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
TC41_0266	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TC41_0268	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TC41_0269	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
TC41_0270	ENOG4105EEI	dihydropteroate synthase
TC41_0271	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TC41_0273	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
TC41_0280	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
TC41_0281	ENOG4105EU0	Major facilitator Superfamily
TC41_0284	ENOG4105CHR	reductase
TC41_0285	ENOG4105CHM	Aminotransferase
TC41_0286	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
TC41_0290	ENOG4105ETD	TRANSCRIPTIONal
TC41_0292	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
TC41_0293	ENOG4105KRI	phosphocarrier protein (HPr
TC41_0294	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
TC41_0295	ENOG4105K6V	RNA polymerase
TC41_0305	ENOG4108JJB	ABC transporter
TC41_0306	ENOG4108JJB	ABC transporter
TC41_0307	ENOG4105VKD	bioY protein
TC41_0308	ENOG4105BZU	Histidine kinase
TC41_0311	ENOG41082J7	Rhodanese domain protein
TC41_0315	ENOG4105DTD	Dehydrogenase
TC41_0317	ENOG4105WMR	Protein CrcB homolog
TC41_0323	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TC41_0324	ENOG4107RSM	transcriptional regulator
TC41_0327	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
TC41_0328	ENOG4105C08	Histidine kinase
TC41_0329	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
TC41_0330	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
TC41_0331	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
TC41_0334	ENOG4105CPC	Aldo Keto reductase
TC41_0337	ENOG4105EQ0	Major Facilitator superfamily
TC41_0338	ENOG4105VRS	hydrolase family 18
TC41_0339	ENOG4105DFW	ABC transporter
TC41_0340	ENOG4105C2J	ABC transporter
TC41_0341	ENOG4108HWW	ABC transporter
TC41_0345	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TC41_0346	ENOG4108V06	Glutathione peroxidase
TC41_0356	ENOG4106WTF	Glycosyl transferase, family 2
TC41_0357	ENOG4105CNU	cell division protein FtsK
TC41_0361	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TC41_0367	ENOG4105CNU	cell division protein FtsK
TC41_0374	ENOG4105E5H	Transposase
TC41_0377	ENOG4105CW7	secretion protein, HlyD family
TC41_0378	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TC41_0381	ENOG4105CNU	cell division protein FtsK
TC41_0385	ENOG4105C19	ABC transporter
TC41_0386	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TC41_0388	ENOG4108RVA	ribokinase
TC41_0390	ENOG4105EYH	Exonuclease
TC41_0391	ENOG410605W	Major Facilitator
TC41_0392	ENOG4105C59	p-type ATPase
TC41_0393	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_0395	ENOG4105EMN	RNA polymerase sigma factor
TC41_0398	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
TC41_0399	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
TC41_0400	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
TC41_0405	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
TC41_0407	ENOG4105D6E	homoserine dehydrogenase
TC41_0409	ENOG4107QHF	type ii secretion system protein e
TC41_0410	ENOG4105D7Q	type ii secretion system
TC41_0413	ENOG4108VAU	general secretion pathway protein G
TC41_0422	ENOG4105CZX	twitching motility protein
TC41_0425	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
TC41_0426	ENOG4108I5C	dEAD DEAH box helicase
TC41_0428	ENOG4108JPW	Aminotransferase
TC41_0429	ENOG4108JUB	Transcriptional regulator
TC41_0437	ENOG4105C8Y	Acetylornithine aminotransferase
TC41_0438	ENOG4105C26	Dehydrogenase
TC41_0439	ENOG4108JUB	Transcriptional regulator
TC41_0442	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TC41_0443	ENOG4105BZ1	(ABC) transporter
TC41_0444	ENOG4105BZ1	(ABC) transporter
TC41_0448	ENOG4105IEH	endo-beta-N-acetylglucosaminidase
TC41_0449	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
TC41_0450	ENOG4105ID8	Transcriptional regulator, ARAC family
TC41_0452	ENOG4105EBR	Carboxylesterase
TC41_0453	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
TC41_0455	ENOG4105D2S	major facilitator superfamily
TC41_0457	ENOG4105ERH	Fumarylacetoacetate hydrolase
TC41_0458	ENOG4105C26	Dehydrogenase
TC41_0462	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TC41_0464	ENOG4105EYF	MMPL domain protein
TC41_0467	ENOG41061WM	D-Alanyl-D-Alanine
TC41_0468	ENOG4105BZ4	penicillin-binding protein
TC41_0473	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
TC41_0479	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
TC41_0480	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
TC41_0481	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
TC41_0482	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
TC41_0484	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
TC41_0485	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
TC41_0486	ENOG4108ESY	Metal dependent phosphohydrolase
TC41_0489	ENOG4105ZKE	UPF0349 protein
TC41_0491	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
TC41_0492	ENOG4105K8N	protein family UPF0079, ATPase
TC41_0494	ENOG410801F	ribosomal-protein-alanine acetyltransferase
TC41_0495	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TC41_0497	ENOG4105C5H	ABC transporter
TC41_0499	ENOG410841Q	phosphoesterase PA-phosphatase related protein
TC41_0500	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
TC41_0502	ENOG4105CEV	competence damage-inducible protein
TC41_0503	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
TC41_0504	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
TC41_0510	ENOG4105WZW	rhodanese family
TC41_0512	ENOG4105WH1	Two component transcriptional regulator luxr family
TC41_0514	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TC41_0517	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TC41_0519	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TC41_0520	ENOG4105C83	adenylosuccinate lyase
TC41_0521	ENOG4105C8V	SAICAR synthetase
TC41_0524	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
TC41_0526	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
TC41_0527	ENOG4105DC1	bifunctional purine biosynthesis protein purh
TC41_0528	ENOG4105C12	Phosphoribosylglycinamide synthetase
TC41_0533	ENOG4105CAK	Cell division ATP-binding protein ftsE
TC41_0534	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
TC41_0536	ENOG4105E14	MotA TolQ exbB proton channel
TC41_0537	ENOG4106VK6	Flagellar motor protein
TC41_0538	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TC41_0539	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
TC41_0540	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
TC41_0544	ENOG4106FI7	cytochrome c-type biogenesis protein
TC41_0546	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
TC41_0547	ENOG4105CHW	UPF0052 protein
TC41_0548	ENOG4105CIE	May be required for sporulation (By similarity)
TC41_0549	ENOG4105KRI	phosphocarrier protein (HPr
TC41_0554	ENOG4106I4J	membrane
TC41_0555	ENOG4105C8T	Leucyl-tRNA synthetase
TC41_0559	ENOG4105F4G	Membrane
TC41_0562	ENOG4108I5C	dEAD DEAH box helicase
TC41_0566	ENOG4105CSM	endonuclease III
TC41_0568	ENOG4105E1K	spore germination protein
TC41_0572	ENOG4105C26	Dehydrogenase
TC41_0577	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TC41_0578	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
TC41_0579	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
TC41_0582	ENOG41069M3	Transcriptional regulator
TC41_0584	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
TC41_0590	ENOG4105EBR	Carboxylesterase
TC41_0591	ENOG4105CYN	Serine protein kinase
TC41_0593	ENOG4105ED1	spovr family
TC41_0600	ENOG4105EN6	Membrane
TC41_0602	ENOG4105BZU	Histidine kinase
TC41_0604	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
TC41_0607	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
TC41_0610	ENOG4105CJ1	ABC, transporter
TC41_0612	ENOG4105DVE	abc transporter atp-binding protein
TC41_0613	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
TC41_0614	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
TC41_0615	ENOG4105DXB	Major Facilitator superfamily
TC41_0617	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
TC41_0619	ENOG4108M15	ABC transporter
TC41_0620	ENOG4105KCT	ABC transporter
TC41_0622	ENOG4105BZU	Histidine kinase
TC41_0626	ENOG4105E2S	oxidase) subunit II
TC41_0628	ENOG4105CCU	oxidase (Subunit III)
TC41_0629	ENOG41060D1	Quinol oxidase
TC41_0631	ENOG4105DZ1	carboxypeptidase
TC41_0635	ENOG4105CPC	Aldo Keto reductase
TC41_0636	ENOG4108JB8	alcohol dehydrogenase
TC41_0637	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
TC41_0641	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TC41_0642	ENOG4105BZU	Histidine kinase
TC41_0644	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
TC41_0647	ENOG4108R85	Short chain dehydrogenase
TC41_0648	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
TC41_0650	ENOG4108YM7	Gcn5-related n-acetyltransferase
TC41_0651	ENOG4105C4R	Atp-dependent dna helicase
TC41_0652	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
TC41_0655	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TC41_0656	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TC41_0657	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TC41_0658	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TC41_0659	ENOG4105F6J	Alpha beta hydrolase fold
TC41_0663	ENOG4105D7V	transposase
TC41_0670	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
TC41_0672	ENOG4105DET	Rhamnulokinase
TC41_0677	ENOG4105EF1	ribulokinase
TC41_0678	ENOG4105C2J	ABC transporter
TC41_0679	ENOG4105CNN	ABC, transporter
TC41_0682	ENOG4105DET	Rhamnulokinase
TC41_0684	ENOG4105E98	transcriptional regulator DeoR family
TC41_0686	ENOG4107QR9	Iron-sulfur cluster binding protein
TC41_0687	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
TC41_0689	ENOG4108QY0	Membrane
TC41_0691	ENOG41090VF	Stage v sporulation protein ac
TC41_0692	ENOG4105CZ3	stage V sporulation protein ad
TC41_0694	ENOG4105EXC	Acyl-transferase
TC41_0700	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_0701	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
TC41_0702	ENOG4105C54	Major Facilitator superfamily
TC41_0703	ENOG4105WG9	Conserved Protein
TC41_0704	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
TC41_0707	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
TC41_0710	ENOG4105DPN	Oligoendopeptidase f
TC41_0711	ENOG4105BZU	Histidine kinase
TC41_0713	ENOG4105BZA	Phosphoglycerate kinase
TC41_0714	ENOG4105CP7	Triose-phosphate isomerase
TC41_0716	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TC41_0717	ENOG4105XZU	Preprotein translocase, subunit SecG
TC41_0718	ENOG4105DJ2	Major Facilitator Superfamily
TC41_0719	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
TC41_0720	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
TC41_0721	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
TC41_0723	ENOG4105C26	Dehydrogenase
TC41_0724	ENOG4105GPN	Uncharacterized conserved protein (DUF2294)
TC41_0726	ENOG4108TWJ	NADH dehydrogenase subunit 5
TC41_0728	ENOG4105EVH	UPF0753 protein
TC41_0729	ENOG4105EVH	UPF0753 protein
TC41_0730	ENOG4105EVH	UPF0753 protein
TC41_0732	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
TC41_0736	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TC41_0739	ENOG4105DEN	Luciferase family
TC41_0740	ENOG4107XWI	flavin reductase domain protein, FMN-binding
TC41_0743	ENOG4105EIG	urea carboxylase-associated protein 1
TC41_0744	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
TC41_0747	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
TC41_0748	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
TC41_0757	ENOG4105C3F	Signal peptidase i
TC41_0758	ENOG4105CPC	Aldo Keto reductase
TC41_0759	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
TC41_0765	ENOG4105CMR	udp-glucose 4-epimerase
TC41_0767	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
TC41_0768	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
TC41_0771	ENOG4105E2V	Glycosyltransferase 36
TC41_0772	ENOG4108KUU	Inner membrane metabolite transport protein ydjE
TC41_0774	ENOG4105DXD	2-methylcitrate dehydratase
TC41_0775	ENOG4105CR4	methylisocitrate lyase
TC41_0776	ENOG4105C7B	Threonine dehydratase
TC41_0781	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
TC41_0782	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
TC41_0784	ENOG4105CSH	Transporter
TC41_0785	ENOG4105C26	Dehydrogenase
TC41_0786	ENOG4105C0A	alcohol dehydrogenase
TC41_0787	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_0788	ENOG4107XVH	Transcriptional regulator
TC41_0789	ENOG4105DVM	PP-loop domain protein
TC41_0791	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
TC41_0793	ENOG4105C8M	UPF0272 protein
TC41_0797	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
TC41_0798	ENOG4105CEV	competence damage-inducible protein
TC41_0799	ENOG4107WBR	Protein of unknown function DUF111
TC41_0801	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
TC41_0803	ENOG4105D9G	High-affinity
TC41_0804	ENOG4108RZE	Tetr family transcriptional regulator
TC41_0805	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
TC41_0808	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
TC41_0809	ENOG4105DZS	Phenylacetate-CoA ligase
TC41_0812	ENOG4105C26	Dehydrogenase
TC41_0813	ENOG4108UKI	Enoyl-CoA hydratase
TC41_0814	ENOG4105CHU	acetyl-coa acetyltransferase
TC41_0815	ENOG4107QSV	RmuC domain protein
TC41_0817	ENOG41067MG	lrgb family
TC41_0820	ENOG4107RSM	transcriptional regulator
TC41_0823	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TC41_0827	ENOG4105E39	Enoyl-CoA hydratase
TC41_0828	ENOG4105FR1	rard protein
TC41_0833	ENOG4105BZ1	(ABC) transporter
TC41_0834	ENOG4105BZ1	(ABC) transporter
TC41_0835	ENOG4105BZ1	(ABC) transporter
TC41_0839	ENOG4105BZ1	(ABC) transporter
TC41_0842	ENOG4108ZSU	Uncharacterized conserved protein (DUF2294)
TC41_0843	ENOG4105TMB	Formate nitrite transporter
TC41_0844	ENOG4108IEG	Formate dehydrogenase Alpha subunit
TC41_0855	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TC41_0856	ENOG4105C6X	Major Facilitator
TC41_0862	ENOG4108X4Q	Hydrolase
TC41_0866	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TC41_0867	ENOG4105K63	Thioredoxin
TC41_0868	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
TC41_0869	ENOG4105DKW	ABC transporter
TC41_0870	ENOG4108YYC	ycei family
TC41_0871	ENOG4105KVH	Transcriptional regulator
TC41_0872	ENOG4105CE4	GlcNAc 6-P deacetylase
TC41_0873	ENOG4107RIQ	Sulfate adenylate transferase
TC41_0874	ENOG4108NA0	Uncharacterized conserved protein (COG2071)
TC41_0875	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
TC41_0876	ENOG4105C26	Dehydrogenase
TC41_0877	ENOG4105CPC	Aldo Keto reductase
TC41_0878	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
TC41_0882	ENOG4105C2C	drug resistance transporter, Bcr CflA
TC41_0883	ENOG4105EEM	helicase
TC41_0884	ENOG41075H3	AraC family transcriptional regulator
TC41_0885	ENOG41080V3	Major Facilitator superfamily
TC41_0886	ENOG41082BV	acetyltransferase
TC41_0889	ENOG4108TN2	lmbE family
TC41_0890	ENOG4105KJF	protein tyrosine phosphatase
TC41_0893	ENOG4105SZ6	Thioredoxin
TC41_0894	ENOG4105CD5	CoA-binding domain protein
TC41_0895	ENOG4105C3M	thioredoxin reductase
TC41_0897	ENOG4105DM4	PTS System
TC41_0899	ENOG4105E98	transcriptional regulator DeoR family
TC41_0900	ENOG4105DE4	1-phosphofructokinase
TC41_0901	ENOG4105DM4	PTS System
TC41_0903	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TC41_0904	ENOG4108594	Permease of the drug metabolite transporter
TC41_0906	ENOG4105CZ9	Domain of unknown function (DU1801)
TC41_0907	ENOG41082BM	Transcriptional regulator, arsr family
TC41_0910	ENOG4105C28	cystathionine
TC41_0914	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_0915	ENOG4105DMF	Dehydrogenase
TC41_0917	ENOG4108Z03	MAF-like protein
TC41_0918	ENOG4105CBX	hi0933 family
TC41_0920	ENOG4107QW4	alcohol dehydrogenase
TC41_0921	ENOG4105ETE	Transcriptional regulator (LacI family
TC41_0924	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
TC41_0925	ENOG4105DRS	transport system, permease
TC41_0926	ENOG4107QM5	aconitate hydratase
TC41_0927	ENOG4105ESV	Glycosyl transferase, family 4
TC41_0928	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
TC41_0930	ENOG4107QPD	alcohol dehydrogenase
TC41_0931	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
TC41_0932	ENOG4108I7Y	domain protein
TC41_0933	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
TC41_0934	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
TC41_0935	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
TC41_0936	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
TC41_0937	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
TC41_0938	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
TC41_0939	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
TC41_0940	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
TC41_0944	ENOG4105CIS	alcohol dehydrogenase
TC41_0946	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
TC41_0947	ENOG4108R6K	riboflavin synthase, subunit alpha
TC41_0948	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
TC41_0949	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
TC41_0951	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
TC41_0952	ENOG4108JJB	ABC transporter
TC41_0956	ENOG4105SKE	transcriptional Regulator LysR family
TC41_0957	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
TC41_0961	ENOG4105EMU	Dehydrogenase
TC41_0962	ENOG4105KHC	sulfurtransferase
TC41_0964	ENOG4108TN2	lmbE family
TC41_0965	ENOG4105FDT	acyl-CoA dehydrogenase
TC41_0967	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
TC41_0973	ENOG4108YBP	pseudouridine synthase
TC41_0974	ENOG4107S2Z	UPF0761 membrane protein
TC41_0975	ENOG4105KRF	dihydroneopterin aldolase
TC41_0978	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TC41_0979	ENOG410890F	Dynamin family
TC41_0980	ENOG4105C0H	protease
TC41_0981	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TC41_0982	ENOG4108VD1	dedA family
TC41_0985	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TC41_0988	ENOG4105EUJ	GTP cyclohydrolase i
TC41_0989	ENOG4105DYB	Isoaspartyl dipeptidase
TC41_0992	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
TC41_0993	ENOG4105EMN	RNA polymerase sigma factor
TC41_0996	ENOG4105DCF	alanine dehydrogenase
TC41_0997	ENOG4105VG1	fes assembly suf system protein
TC41_0998	ENOG4105C3K	feS assembly ATPase SufC
TC41_1000	ENOG4105JRK	feS assembly protein SufD
TC41_1002	ENOG4108UNV	SUF system FeS assembly protein, NifU family
TC41_1003	ENOG4105DIW	FeS assembly protein SUFB
TC41_1009	ENOG4105ECY	inositol monophosphatase
TC41_1010	ENOG4105DAP	Nicotinate phosphoribosyltransferase
TC41_1011	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
TC41_1015	ENOG4107QTZ	amino acid
TC41_1019	ENOG4105VV2	
TC41_1020	ENOG4105C0D	helicase
TC41_1025	ENOG4105C0B	DNA polymerase III (alpha subunit)
TC41_1030	ENOG4107YU2	histidine triad (hIT) protein
TC41_1031	ENOG4105F0I	Aminotransferase
TC41_1033	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
TC41_1038	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
TC41_1039	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
TC41_1040	ENOG4105KA0	thioesterase Superfamily protein
TC41_1048	ENOG4105E5H	Transposase
TC41_1065	ENOG4105CNI	cell division protein FtsW
TC41_1067	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
TC41_1068	ENOG4105CNI	cell division protein FtsW
TC41_1073	ENOG4108XFG	YwhD family
TC41_1074	ENOG4105CXN	decarboxylase
TC41_1076	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TC41_1078	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
TC41_1079	ENOG4105DCI	Phosphohydrolase
TC41_1080	ENOG4107ZTW	SNARE associated Golgi
TC41_1081	ENOG4105KZD	Domain of unknown function (DUF1805)
TC41_1082	ENOG4105CN9	Peptidase m42 family protein
TC41_1086	ENOG41069ER	domain protein
TC41_1093	ENOG4105C26	Dehydrogenase
TC41_1095	ENOG41069DP	small acid-soluble spore protein
TC41_1096	ENOG4105EA8	2-Nitropropane dioxygenase
TC41_1097	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
TC41_1098	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
TC41_1104	ENOG4105D5G	Transposase
TC41_1108	ENOG4105DRS	transport system, permease
TC41_1110	ENOG4105CNT	hydrolase family 2
TC41_1114	ENOG4105E5H	Transposase
TC41_1118	ENOG4105C1G	acyl-Coa dehydrogenase
TC41_1119	ENOG4108IPT	Naphthoate synthase
TC41_1120	ENOG4105CHR	reductase
TC41_1121	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_1122	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_1124	ENOG4105ETE	Transcriptional regulator (LacI family
TC41_1127	ENOG4105DDQ	anthranilate synthase
TC41_1128	ENOG4105CRQ	synthase (Component I)
TC41_1130	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
TC41_1132	ENOG4105CAS	nag kinase
TC41_1133	ENOG4105C8Y	Acetylornithine aminotransferase
TC41_1137	ENOG4105DBV	ornithine carbamoyltransferase
TC41_1138	ENOG4105CDH	Citrulline--aspartate ligase
TC41_1139	ENOG4105CH7	arginosuccinase
TC41_1145	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
TC41_1152	ENOG4105C0D	helicase
TC41_1162	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
TC41_1164	ENOG4105CZV	ABC transporter
TC41_1168	ENOG4105WZW	rhodanese family
TC41_1169	ENOG4105K63	Thioredoxin
TC41_1174	ENOG4105CS1	NAD(P)H quinone oxidoreductase
TC41_1175	ENOG4105DRR	Transcriptional regulator, GntR family
TC41_1176	ENOG4106HK8	GPR1 FUN34 yaaH family protein
TC41_1177	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TC41_1178	ENOG41085AS	UPF0473 protein
TC41_1183	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
TC41_1184	ENOG4105C3J	Cysteine desulfurase
TC41_1185	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TC41_1189	ENOG4108Q5U	germination protein, ger(x)c family
TC41_1190	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
TC41_1191	ENOG41074B2	UPF0747 protein
TC41_1192	ENOG4108V6E	Cell division protein mraZ
TC41_1193	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
TC41_1195	ENOG4105CJN	penicillin-binding protein
TC41_1196	ENOG4105CJN	penicillin-binding protein
TC41_1197	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
TC41_1198	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
TC41_1199	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
TC41_1200	ENOG4105CNI	cell division protein FtsW
TC41_1201	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
TC41_1202	ENOG4107R4N	Cell wall formation (By similarity)
TC41_1203	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TC41_1204	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
TC41_1206	ENOG4107Y5K	Resolvase
TC41_1207	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TC41_1211	ENOG4105K67	small basic protein
TC41_1212	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
TC41_1213	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TC41_1217	ENOG4108AWX	Sporulation factor SpoIIGA 
TC41_1218	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TC41_1220	ENOG4105WR5	sporulation protein, YlmC YmxH family
TC41_1222	ENOG4105DFA	alanine racemase domain protein
TC41_1229	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
TC41_1230	ENOG4105C34	Pseudouridine synthase
TC41_1231	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
TC41_1232	ENOG4105CXT	aspartate transcarbamylase
TC41_1233	ENOG4105CD3	dihydroorotase
TC41_1236	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
TC41_1237	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
TC41_1240	ENOG4105D82	Glutamate dehydrogenase
TC41_1241	ENOG4105F23	Fibronectin-binding protein
TC41_1242	ENOG4105F23	Fibronectin-binding protein
TC41_1244	ENOG4105DSJ	YicC domain protein
TC41_1246	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
TC41_1247	ENOG4105C25	Primosomal protein n'
TC41_1248	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
TC41_1249	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
TC41_1250	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TC41_1251	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
TC41_1252	ENOG4108ZF3	Phosphatase
TC41_1253	ENOG4105D9P	serine threonine protein kinase
TC41_1255	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
TC41_1257	ENOG4105VB9	50S ribosomal protein l28
TC41_1258	ENOG4105CB5	ATP-dependent DNA helicase recG
TC41_1260	ENOG4105DJ4	phosphatidylserine decarboxylase
TC41_1261	ENOG4105CMR	udp-glucose 4-epimerase
TC41_1263	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TC41_1264	ENOG4106H78	methyltransferase
TC41_1265	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
TC41_1266	ENOG4105D78	K07001 NTE family protein
TC41_1268	ENOG41067VY	50S ribosomal protein L32
TC41_1270	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
TC41_1271	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
TC41_1272	ENOG4105CHR	reductase
TC41_1273	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TC41_1274	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
TC41_1275	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
TC41_1276	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
TC41_1277	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TC41_1278	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
TC41_1280	ENOG4105K5M	30s ribosomal protein S16
TC41_1281	ENOG4105VB6	UPF0109 protein
TC41_1284	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
TC41_1287	ENOG4105CRQ	synthase (Component I)
TC41_1288	ENOG4105C34	Pseudouridine synthase
TC41_1290	ENOG4105FAA	peptidase M23
TC41_1291	ENOG4108S4H	thioesterase Superfamily protein
TC41_1297	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
TC41_1298	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
TC41_1299	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TC41_1301	ENOG4105D00	flagellar biosynthetic protein flhB
TC41_1303	ENOG4105C0P	Mg chelatase subunit ChlI
TC41_1305	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
TC41_1307	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
TC41_1311	ENOG4105K4H	Nlp p60 protein
TC41_1314	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TC41_1315	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
TC41_1317	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TC41_1318	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
TC41_1320	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
TC41_1322	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
TC41_1323	ENOG4108ZC9	flagellar basal-body rod protein flgc
TC41_1324	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
TC41_1325	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
TC41_1326	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TC41_1335	ENOG4105BZE	flagellar hook protein, FlgE
TC41_1336	ENOG4105BZE	flagellar hook protein, FlgE
TC41_1339	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TC41_1340	ENOG4105DD5	Flagellar motor switch protein
TC41_1341	ENOG4107YTP	response regulator receiver protein
TC41_1343	ENOG4105CN7	Flagellar biosynthetic protein FliP
TC41_1344	ENOG4105VS8	Flagellar biosynthetic protein fliq
TC41_1346	ENOG4105D00	flagellar biosynthetic protein flhB
TC41_1347	ENOG4105D7B	Flagellar biosynthesis protein flha
TC41_1348	ENOG4105FZW	flagellar biosynthesis regulator FlhF
TC41_1351	ENOG4105CBS	Chea signal transduction histidine kinase
TC41_1352	ENOG4108V3W	Chemotaxis protein, CheW
TC41_1354	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
TC41_1358	ENOG4105CE9	30S ribosomal protein S2
TC41_1359	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
TC41_1360	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
TC41_1361	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
TC41_1362	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TC41_1363	ENOG4105KNE	Phosphatidate cytidylyltransferase
TC41_1364	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
TC41_1365	ENOG4105DZP	Membrane-associated zinc metalloprotease
TC41_1366	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
TC41_1368	ENOG4105CQC	Prephenate dehydratase
TC41_1369	ENOG4105CI3	gtp-binding protein typa
TC41_1370	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
TC41_1371	ENOG4105CHV	Transcription elongation factor NusA
TC41_1372	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
TC41_1374	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
TC41_1375	ENOG4105SFS	phosphoesterase RecJ domain protein
TC41_1376	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TC41_1377	ENOG4105DTN	riboflavin biosynthesis protein ribF
TC41_1379	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TC41_1380	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TC41_1381	ENOG4107VMI	polysaccharide deacetylase
TC41_1382	ENOG4105C1V	Peptidase, M16
TC41_1384	ENOG4105E35	Dipicolinate synthase subunit A
TC41_1385	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
TC41_1386	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
TC41_1388	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TC41_1391	ENOG4105C1G	acyl-Coa dehydrogenase
TC41_1393	ENOG4105C26	Dehydrogenase
TC41_1394	ENOG4105E39	Enoyl-CoA hydratase
TC41_1395	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TC41_1396	ENOG4105CHU	acetyl-coa acetyltransferase
TC41_1398	ENOG4107RDP	Dehydrogenase
TC41_1400	ENOG4105CN5	Metallo-Beta-Lactamase
TC41_1401	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
TC41_1403	ENOG4105CNU	cell division protein FtsK
TC41_1409	ENOG4108VPT	UPF0234 protein
TC41_1410	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
TC41_1411	ENOG4105CEV	competence damage-inducible protein
TC41_1412	ENOG4105C1J	atp-dependent rna helicase
TC41_1413	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
TC41_1415	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
TC41_1416	ENOG4105MCT	stage V sporulation protein S
TC41_1423	ENOG410839P	
TC41_1425	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TC41_1427	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
TC41_1428	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
TC41_1429	ENOG4107YX5	Pfam:DUF548
TC41_1430	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
TC41_1431	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
TC41_1442	ENOG4105DQ6	Transposase
TC41_1449	ENOG4105E1K	spore germination protein
TC41_1454	ENOG4105CMR	udp-glucose 4-epimerase
TC41_1455	ENOG4105CKP	Polysaccharide Biosynthesis Protein
TC41_1458	ENOG4106F1P	AAA ATPase, central domain protein
TC41_1462	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
TC41_1463	ENOG4105CXI	aluminum resistance protein
TC41_1464	ENOG4105KV4	Transcriptional regulator
TC41_1465	ENOG4105C5F	glutamine synthetase
TC41_1468	ENOG4105CTX	dehydratase
TC41_1469	ENOG4105DH8	myo-inositol catabolism
TC41_1470	ENOG4107QZW	Altronate oxidoreductase
TC41_1472	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
TC41_1473	ENOG4108HCJ	Hydrolase
TC41_1474	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
TC41_1479	ENOG4105BZU	Histidine kinase
TC41_1484	ENOG4105C10	Electron transfer flavoprotein
TC41_1485	ENOG4105BZJ	Electron transfer flavoprotein
TC41_1486	ENOG4107Z3H	Transcriptional regulator, TetR family
TC41_1487	ENOG4105DF6	Fe-S oxidoreductase
TC41_1489	ENOG4105CHU	acetyl-coa acetyltransferase
TC41_1490	ENOG4105C1G	acyl-Coa dehydrogenase
TC41_1491	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_1493	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TC41_1494	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TC41_1495	ENOG4105C0X	amino acid
TC41_1496	ENOG4105EM2	membrane
TC41_1500	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
TC41_1501	ENOG4105C2X	Arabinose 5-phosphate isomerase
TC41_1503	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
TC41_1504	ENOG4105CBT	Fructose-1,6-bisphosphatase
TC41_1520	ENOG4105J4Q	Transcriptional regulator
TC41_1523	ENOG4108S0S	Nucleotidyl transferase
TC41_1524	ENOG4105C5F	glutamine synthetase
TC41_1525	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TC41_1526	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TC41_1528	ENOG4108Z7R	Chaperone CsaA
TC41_1531	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
TC41_1532	ENOG4105CPF	Cell wall formation (By similarity)
TC41_1534	ENOG4105C5S	asparaginyl-tRNA synthetase
TC41_1535	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TC41_1538	ENOG4105YAC	
TC41_1539	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
TC41_1541	ENOG41080U2	Amidohydrolase family
TC41_1542	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TC41_1543	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
TC41_1546	ENOG4105FDF	Could be involved in DNA repair (By similarity)
TC41_1547	ENOG4105DVT	helicase
TC41_1550	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
TC41_1551	ENOG4105CPK	Glycosyl transferase (Group 1
TC41_1552	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
TC41_1553	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
TC41_1555	ENOG4105H20	Sporulation integral membrane protein YlbJ
TC41_1556	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
TC41_1557	ENOG4108K88	Membrane
TC41_1558	ENOG4108JYZ	YitT family
TC41_1561	ENOG4105EVN	Prephenate dehydrogenase
TC41_1562	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
TC41_1563	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
TC41_1564	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
TC41_1565	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
TC41_1566	ENOG4105DK0	Indole-3-glycerol phosphate synthase
TC41_1567	ENOG4107S1N	anthranilate phosphoribosyltransferase
TC41_1568	ENOG4105KHN	chorismate mutase
TC41_1569	ENOG4105D49	3-dehydroquinate synthase
TC41_1570	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
TC41_1571	ENOG4105CN9	Peptidase m42 family protein
TC41_1572	ENOG4105CN9	Peptidase m42 family protein
TC41_1573	ENOG4105CN9	Peptidase m42 family protein
TC41_1576	ENOG4105K4H	Nlp p60 protein
TC41_1578	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
TC41_1582	ENOG4108JQC	penicillin-binding protein 1A
TC41_1585	ENOG4105BZU	Histidine kinase
TC41_1587	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TC41_1588	ENOG4105EAH	synthase
TC41_1589	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TC41_1591	ENOG4105WP2	Tryptophan RNA-binding attenuator protein
TC41_1592	ENOG4105DQ4	alcohol dehydrogenase
TC41_1593	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
TC41_1595	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
TC41_1596	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
TC41_1598	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TC41_1600	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TC41_1603	ENOG4105CAT	Cytidine monophosphate kinase
TC41_1605	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
TC41_1610	ENOG4108S6Z	Negative regulator of genetic competence
TC41_1611	ENOG4105ETE	Transcriptional regulator (LacI family
TC41_1615	ENOG4105ENA	helicase
TC41_1615	ENOG4105ENA	helicase
TC41_1619	ENOG4105C0H	protease
TC41_1622	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
TC41_1624	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
TC41_1626	ENOG4105BZU	Histidine kinase
TC41_1627	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TC41_1629	ENOG4105FE9	pseudouridine synthase
TC41_1631	ENOG4108JIC	nucleoside recognition domain protein
TC41_1632	ENOG4105KBJ	sporulation protein ytfj
TC41_1634	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
TC41_1635	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
TC41_1636	ENOG4108Z4T	Peptidase M50
TC41_1639	ENOG4105G6R	Stage v sporulation protein ae
TC41_1641	ENOG4105CZ3	stage V sporulation protein ad
TC41_1642	ENOG41090VF	Stage v sporulation protein ac
TC41_1643	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TC41_1647	ENOG4105DZ1	carboxypeptidase
TC41_1648	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
TC41_1649	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TC41_1653	ENOG4108YZ4	nudix hydrolase
TC41_1654	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
TC41_1655	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
TC41_1656	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
TC41_1657	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TC41_1659	ENOG4105VRS	hydrolase family 18
TC41_1664	ENOG4107JTW	chlorite dismutase
TC41_1668	ENOG4105S1Z	Stage IV sporulation protein B
TC41_1669	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
TC41_1670	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TC41_1672	ENOG4105DX0	Hemolysin A
TC41_1675	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TC41_1676	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TC41_1677	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TC41_1678	ENOG4105CAY	ferredoxin--nadp reductase
TC41_1680	ENOG4105M7K	Involved in the transcription termination process (By similarity)
TC41_1684	ENOG4108ZSR	alkaline shock protein
TC41_1685	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
TC41_1692	ENOG4105KQ4	Stage iii sporulation protein ad
TC41_1695	ENOG4105CD2	stage iii sporulation protein aa
TC41_1696	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
TC41_1697	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
TC41_1698	ENOG4107TB6	phosphoglycerate mutase
TC41_1699	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TC41_1700	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TC41_1701	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
TC41_1702	ENOG4105C0D	helicase
TC41_1704	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
TC41_1705	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
TC41_1707	ENOG4105KRN	Transcriptional regulator, abrb family
TC41_1720	ENOG4107QJE	Chromosome Partitioning Protein
TC41_1722	ENOG4105CXC	rtn protein
TC41_1741	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TC41_1742	ENOG4105BZU	Histidine kinase
TC41_1749	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
TC41_1750	ENOG4105WXW	Antirepressor
TC41_1769	ENOG4105FA0	parb-like partition protein
TC41_1778	ENOG4105FA0	parb-like partition protein
TC41_1780	ENOG4105QIV	RNA polymerase
TC41_1788	ENOG4105DFE	Dna adenine methylase
TC41_1797	ENOG4105E5H	Transposase
TC41_1798	ENOG4105KTU	Transcriptional regulator, arsr family
TC41_1799	ENOG4105PGM	cation diffusion facilitator family transporter
TC41_1801	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
TC41_1804	ENOG4106QJ6	Integrase catalytic subunit
TC41_1808	ENOG4105CHR	reductase
TC41_1810	ENOG4105CUB	amino acid
TC41_1816	ENOG4105E5H	Transposase
TC41_1818	ENOG4105E5H	Transposase
TC41_1825	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
TC41_1828	ENOG4105ERH	Fumarylacetoacetate hydrolase
TC41_1831	ENOG4105CSH	Transporter
TC41_1832	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_1833	ENOG4105CHU	acetyl-coa acetyltransferase
TC41_1834	ENOG4105E39	Enoyl-CoA hydratase
TC41_1835	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
TC41_1843	ENOG4105E5H	Transposase
TC41_1850	ENOG4105UMD	exodeoxyribonuclease X
TC41_1866	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TC41_1889	ENOG41061P8	Persistence to inhibition of murein or DNA biosynthesis regulatory protein
TC41_1893	ENOG4108IMY	Transcriptional regulator
TC41_1895	ENOG4108IMY	Transcriptional regulator
TC41_1897	ENOG4105VTR	Integrase
TC41_1905	ENOG4107QHF	type ii secretion system protein e
TC41_1908	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TC41_1910	ENOG4105K46	50S ribosomal protein l27
TC41_1911	ENOG41087JC	Protein of unknown function (DUF464)
TC41_1915	ENOG4107QMS	site-determining protein
TC41_1916	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
TC41_1919	ENOG4105DFF	Rod shape-determining protein mreb
TC41_1920	ENOG4105W5Q	DNA repair protein (RadC
TC41_1922	ENOG4105HSS	phospholipase C
TC41_1924	ENOG41069ER	domain protein
TC41_1925	ENOG4105DFU	Cell wall formation (By similarity)
TC41_1926	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TC41_1927	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TC41_1932	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
TC41_1934	ENOG4105D52	delta-aminolevulinic acid dehydratase
TC41_1936	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
TC41_1938	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
TC41_1939	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
TC41_1940	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TC41_1941	ENOG4108IUQ	atp-dependent protease
TC41_1942	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
TC41_1943	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
TC41_1944	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
TC41_1945	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TC41_1946	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
TC41_1947	ENOG41067TZ	transcriptional regulator, MarR family
TC41_1948	ENOG4105C1G	acyl-Coa dehydrogenase
TC41_1949	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
TC41_1952	ENOG4105PFC	Transcriptional regulator
TC41_1953	ENOG4105C87	Aminotransferase class I and II
TC41_1955	ENOG4105FDP	GntR family transcriptional regulator
TC41_1956	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TC41_1959	ENOG4105E33	succinate dehydrogenase
TC41_1961	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
TC41_1962	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
TC41_1964	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
TC41_1966	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TC41_1968	ENOG4105UPD	Calcium Proton
TC41_1976	ENOG41067TZ	transcriptional regulator, MarR family
TC41_1980	ENOG4105E66	phosphoriboisomerase A
TC41_1981	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TC41_1984	ENOG4105PGM	cation diffusion facilitator family transporter
TC41_1986	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
TC41_1987	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
TC41_1988	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TC41_1990	ENOG410838F	Glycosyl transferase family 2
TC41_1991	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
TC41_1992	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
TC41_1995	ENOG4105CS2	ec 3.2.1.21
TC41_1996	ENOG4108JQ7	(ABC) transporter
TC41_2002	ENOG4108Z4U	Ferredoxin
TC41_2003	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
TC41_2007	ENOG4105MXW	flavin reductase domain protein, FMN-binding
TC41_2011	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
TC41_2016	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
TC41_2017	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
TC41_2018	ENOG4105E4F	Isochorismate synthase
TC41_2019	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_2020	ENOG4108IPT	Naphthoate synthase
TC41_2021	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
TC41_2022	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
TC41_2024	ENOG4108IEG	Formate dehydrogenase Alpha subunit
TC41_2025	ENOG4105C7Z	Conserved Protein
TC41_2026	ENOG4105C7Z	Conserved Protein
TC41_2029	ENOG4108UZ3	Transporter
TC41_2031	ENOG4105ETU	transcriptional activator (TenA
TC41_2033	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
TC41_2034	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TC41_2038	ENOG4105E1K	spore germination protein
TC41_2039	ENOG4105CBC	glutamate synthase
TC41_2041	ENOG4108JJ9	ABC, transporter
TC41_2042	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
TC41_2043	ENOG4105C4M	(Ubiquinol oxidase) subunit I
TC41_2044	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TC41_2046	ENOG41067TZ	transcriptional regulator, MarR family
TC41_2048	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
TC41_2049	ENOG4105EHG	Permease protein
TC41_2050	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
TC41_2057	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
TC41_2058	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
TC41_2061	ENOG4107R33	ppx gppa phosphatase
TC41_2067	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
TC41_2075	ENOG4105BZU	Histidine kinase
TC41_2077	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
TC41_2078	ENOG4105BZU	Histidine kinase
TC41_2079	ENOG4105ETX	regulatoR
TC41_2085	ENOG4105EGD	dinuclear metal center protein, YbgI family
TC41_2088	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TC41_2089	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
TC41_2091	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
TC41_2093	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
TC41_2095	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
TC41_2096	ENOG4105CTJ	Metal Dependent Phosphohydrolase
TC41_2097	ENOG4105C9A	Phoh family
TC41_2100	ENOG4105KTH	gatB Yqey
TC41_2101	ENOG4105VCC	30S ribosomal protein S21
TC41_2103	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
TC41_2104	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TC41_2105	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
TC41_2106	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TC41_2107	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TC41_2109	ENOG4105CFG	Acts as a chaperone (By similarity)
TC41_2110	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TC41_2111	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
TC41_2113	ENOG4105CSA	Coproporphyrinogen iii oxidase
TC41_2115	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
TC41_2118	ENOG4105E4C	Lytic transglycosylase catalytic
TC41_2120	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
TC41_2125	ENOG4105KQC	Competence protein
TC41_2127	ENOG4105KST	dependent repressor
TC41_2128	ENOG4105DXX	methyltransferase
TC41_2130	ENOG4108WF2	Metal Dependent Phosphohydrolase
TC41_2131	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
TC41_2132	ENOG4105E2X	shikimate dehydrogenase
TC41_2135	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TC41_2139	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
TC41_2140	ENOG4105VBH	UPF0297 protein
TC41_2141	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TC41_2142	ENOG4105C02	permease
TC41_2143	ENOG41060CR	
TC41_2144	ENOG4107QI6	Cysteine desulfurase
TC41_2147	ENOG4105D7V	transposase
TC41_2150	ENOG4108UXE	Protein tyrosine phosphatase
TC41_2151	ENOG4107R5R	arsenical pump membrane protein
TC41_2155	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_2156	ENOG4105C9M	aspartyl-trna synthetase
TC41_2157	ENOG4105CUT	histidyl-tRNA synthetase
TC41_2159	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
TC41_2163	ENOG4105CJ1	ABC, transporter
TC41_2165	ENOG4105D94	Major Facilitator Superfamily
TC41_2171	ENOG4105E39	Enoyl-CoA hydratase
TC41_2172	ENOG4107QX3	carboxylase
TC41_2173	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
TC41_2174	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
TC41_2175	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
TC41_2176	ENOG4105C1G	acyl-Coa dehydrogenase
TC41_2177	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TC41_2178	ENOG4105CHU	acetyl-coa acetyltransferase
TC41_2179	ENOG4108IIH	CoA-transferase subunit B
TC41_2180	ENOG4105D6N	CoA-transferase, subunit a
TC41_2184	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
TC41_2185	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TC41_2190	ENOG4105CPC	Aldo Keto reductase
TC41_2191	ENOG4107YEI	lmbE family
TC41_2192	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TC41_2193	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
TC41_2194	ENOG41068JE	domain protein
TC41_2195	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
TC41_2196	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
TC41_2197	ENOG41079KZ	Major Facilitator Superfamily
TC41_2198	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TC41_2203	ENOG4105DZ1	carboxypeptidase
TC41_2204	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
TC41_2206	ENOG4108Y6J	UPF0403 protein
TC41_2207	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
TC41_2208	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
TC41_2209	ENOG4105C1Q	protoporphyrinogen oxidase
TC41_2215	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
TC41_2216	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
TC41_2217	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
TC41_2218	ENOG41076HS	cation diffusion facilitator family transporter
TC41_2219	ENOG4107SBW	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TC41_2220	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TC41_2222	ENOG4105CKP	Polysaccharide Biosynthesis Protein
TC41_2223	ENOG4108QG2	Membrane
TC41_2224	ENOG4105BZU	Histidine kinase
TC41_2227	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
TC41_2228	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
TC41_2231	ENOG4108WZW	RNA polymerase sigma
TC41_2232	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
TC41_2233	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
TC41_2234	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
TC41_2236	ENOG4105CDY	transcriptional regulatory protein
TC41_2237	ENOG4105C4K	Nad synthetase
TC41_2238	ENOG4105C4K	Nad synthetase
TC41_2243	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
TC41_2245	ENOG4105BZ4	penicillin-binding protein
TC41_2246	ENOG4105C98	muts2 protein
TC41_2249	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
TC41_2250	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
TC41_2251	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TC41_2253	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
TC41_2254	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
TC41_2255	ENOG4105EIE	fructose-bisphosphate aldolase
TC41_2256	ENOG4105CTQ	phosphohexokinase
TC41_2257	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
TC41_2258	ENOG4105C8Q	Methyl-accepting chemotaxis
TC41_2260	ENOG4105KRI	phosphocarrier protein (HPr
TC41_2264	ENOG4105DWT	malate dehydrogenase (quinone)
TC41_2265	ENOG4105C7S	Dehydrogenase
TC41_2266	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
TC41_2268	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TC41_2271	ENOG4105DG6	mannose-6-phosphate isomerase
TC41_2272	ENOG4105C5I	Dehydrogenase
TC41_2276	ENOG4105CK5	oxidoreductase
TC41_2277	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
TC41_2282	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
TC41_2285	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
TC41_2287	ENOG4105CUB	amino acid
TC41_2288	ENOG4105WEF	catalase
TC41_2292	ENOG4108RWN	rrna methyltransferase
TC41_2293	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
TC41_2294	ENOG4105VJV	50s ribosomal protein L35
TC41_2297	ENOG41066VF	YeeE YedE family protein
TC41_2299	ENOG4105C22	threonyL-tRNA synthetase
TC41_2304	ENOG4105CMG	Carbohydrate kinase
TC41_2305	ENOG4105C93	Xylose Isomerase
TC41_2306	ENOG4105D2S	major facilitator superfamily
TC41_2325	ENOG4108FN7	Aldo keto reductase
TC41_2326	ENOG4107R5R	arsenical pump membrane protein
TC41_2331	ENOG4107QM2	Aldo Keto reductase
TC41_2332	ENOG4107TYA	transient receptor potential locus
TC41_2334	ENOG4105KZX	Pterin carbinolamine dehydratase
TC41_2337	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
TC41_2339	ENOG4108I69	Glycosyl transferases group 1
TC41_2341	ENOG4107RBB	ABC transporter, permease
TC41_2342	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TC41_2345	ENOG41080XP	Cbs domain
TC41_2347	ENOG4105BZN	citrate synthase
TC41_2348	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
TC41_2349	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TC41_2350	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TC41_2351	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TC41_2352	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TC41_2353	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
TC41_2354	ENOG4108ZP8	Acetolactate synthase small subunit
TC41_2355	ENOG4105C7K	acetolactate synthase
TC41_2356	ENOG4105C01	Dihydroxy-acid dehydratase
TC41_2358	ENOG4105CM2	brancheD-chain amino acid aminotransferase
TC41_2359	ENOG4105D6E	homoserine dehydrogenase
TC41_2360	ENOG4105D7K	pfkb domain protein
TC41_2364	ENOG4107T3P	ABC, transporter
TC41_2365	ENOG4105ETE	Transcriptional regulator (LacI family
TC41_2369	ENOG4105D3R	alkyl hydroperoxide reductase
TC41_2370	ENOG4105KPV	Transcriptional regulator
TC41_2376	ENOG4105KRN	Transcriptional regulator, abrb family
TC41_2392	ENOG4105CXC	rtn protein
TC41_2408	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TC41_2409	ENOG4105BZU	Histidine kinase
TC41_2417	ENOG4105WXW	Antirepressor
TC41_2427	ENOG4105DZP	Membrane-associated zinc metalloprotease
TC41_2438	ENOG4105FA0	parb-like partition protein
TC41_2447	ENOG4105QIV	RNA polymerase
TC41_2457	ENOG4105DFE	Dna adenine methylase
TC41_2460	ENOG4105DZP	Membrane-associated zinc metalloprotease
TC41_2465	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
TC41_2469	ENOG410904A	RNA polymerase
TC41_2473	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
TC41_2479	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TC41_2480	ENOG4105UMD	exodeoxyribonuclease X
TC41_2490	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TC41_2502	ENOG4105WXW	Antirepressor
TC41_2515	ENOG4108IMY	Transcriptional regulator
TC41_2521	ENOG4105VRS	hydrolase family 18
TC41_2523	ENOG4108IQI	permease
TC41_2530	ENOG4105BZ1	(ABC) transporter
TC41_2531	ENOG4105BZ1	(ABC) transporter
TC41_2534	ENOG4105HJK	ABC transporter
TC41_2536	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TC41_2537	ENOG4105DEF	Extracellular solute-binding protein, family 5
TC41_2538	ENOG4108JQ7	(ABC) transporter
TC41_2539	ENOG4105C3U	ABC transporter
TC41_2540	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
TC41_2542	ENOG4108KMH	lipoate-protein ligase a
TC41_2543	ENOG4105GR3	Histidine kinase
TC41_2544	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TC41_2545	ENOG4105DND	Transcriptional regulator
TC41_2546	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
TC41_2547	ENOG4105C2F	Histidine kinase
TC41_2552	ENOG4105EQD	regulatoR
TC41_2555	ENOG4105CNN	ABC, transporter
TC41_2556	ENOG4105C2J	ABC transporter
TC41_2557	ENOG4105CGK	Exodeoxyribonuclease III
TC41_2562	ENOG4105CS9	pantothenic acid kinase
TC41_2563	ENOG4105BZ1	(ABC) transporter
TC41_2564	ENOG4105BZ1	(ABC) transporter
TC41_2565	ENOG4107XVH	Transcriptional regulator
TC41_2567	ENOG4105E0X	reductase
TC41_2569	ENOG4105ECY	inositol monophosphatase
TC41_2570	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
TC41_2571	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TC41_2573	ENOG4105BZW	Glycerate kinase
TC41_2587	ENOG41069D7	Methyl-accepting chemotaxis
TC41_2590	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
TC41_2595	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TC41_2597	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
TC41_2600	ENOG4105C6X	Major Facilitator
TC41_2605	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
TC41_2606	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
TC41_2611	ENOG4105CPQ	Dehydrogenase
TC41_2613	ENOG4107RF6	penicillin-binding protein
TC41_2625	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
TC41_2626	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
TC41_2627	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
TC41_2630	ENOG4105CQC	Prephenate dehydratase
TC41_2632	ENOG4108HMX	isocitrate dehydrogenase (NADP)
TC41_2634	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
TC41_2635	ENOG4105C31	Tryptophanyl-tRNA synthetase
TC41_2636	ENOG4105CA9	Pyruvate kinase
TC41_2637	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
TC41_2638	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
TC41_2640	ENOG4105C0B	DNA polymerase III (alpha subunit)
TC41_2647	ENOG4105C6T	cysteine synthase
TC41_2648	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
TC41_2650	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
TC41_2655	ENOG4105E8R	UPF0173 metal-dependent hydrolase
TC41_2656	ENOG41084CE	UPF0342 protein
TC41_2657	ENOG4108Z18	K06886 hemoglobin
TC41_2659	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
TC41_2661	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TC41_2663	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
TC41_2665	ENOG4105D7W	serine acetyltransferase
TC41_2666	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TC41_2668	ENOG4105KGF	protein, YerC YecD
TC41_2670	ENOG4107R16	Multicopper oxidase
TC41_2679	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
TC41_2680	ENOG41089WN	small, acid-soluble spore protein tlp
TC41_2683	ENOG4105CPQ	Dehydrogenase
TC41_2684	ENOG4105C1G	acyl-Coa dehydrogenase
TC41_2685	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_2686	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TC41_2687	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
TC41_2688	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
TC41_2689	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_2690	ENOG4105C1G	acyl-Coa dehydrogenase
TC41_2691	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
TC41_2694	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
TC41_2700	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
TC41_2701	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
TC41_2703	ENOG4105CPC	Aldo Keto reductase
TC41_2705	ENOG4105C8Q	Methyl-accepting chemotaxis
TC41_2707	ENOG4105CIY	formyltetrahydrofolate deformylase
TC41_2710	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
TC41_2711	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
TC41_2712	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
TC41_2713	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
TC41_2715	ENOG4105CKK	Glycosyl transferase, family 2
TC41_2716	ENOG4105EDW	glycosyl transferase, family 39
TC41_2717	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
TC41_2718	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TC41_2719	ENOG4105CW7	secretion protein, HlyD family
TC41_2720	ENOG4107RF6	penicillin-binding protein
TC41_2721	ENOG4105CND	Glycosyl transferase, family 2
TC41_2723	ENOG41061P3	phosphosulfolactate synthase
TC41_2725	ENOG4105GEU	Spore germination protein
TC41_2727	ENOG4108Q5U	germination protein, ger(x)c family
TC41_2728	ENOG4105E1K	spore germination protein
TC41_2729	ENOG4105C0H	protease
TC41_2733	ENOG4105EWU	Squalene--hopene cyclase
TC41_2736	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TC41_2737	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
TC41_2738	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
TC41_2746	ENOG4105E3B	Multicopper oxidase
TC41_2747	ENOG4107STQ	Multicopper oxidase
TC41_2749	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
TC41_2750	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
TC41_2753	ENOG4105DDC	Oxidoreductase domain protein
TC41_2755	ENOG4105ETE	Transcriptional regulator (LacI family
TC41_2759	ENOG4105C5F	glutamine synthetase
TC41_2760	ENOG4105BZU	Histidine kinase
TC41_2761	ENOG4107VXZ	Hydrolase
TC41_2763	ENOG4105C3U	ABC transporter
TC41_2764	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TC41_2765	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TC41_2766	ENOG4108J59	Extracellular solute-binding protein, family 5
TC41_2768	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
TC41_2769	ENOG4108EU5	L-aspartate oxidase
TC41_2770	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
TC41_2772	ENOG4105D06	uba thif-type nad fad binding protein
TC41_2773	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
TC41_2775	ENOG41080HI	glycine oxidase
TC41_2776	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TC41_2777	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
TC41_2783	ENOG4107QSI	ABC, transporter
TC41_2787	ENOG4105DJB	Major Facilitator Superfamily
TC41_2793	ENOG4107R8N	Glycosyl transferase, family 2
TC41_2799	ENOG4108Z0Z	intracellular protease Pfpi family
TC41_2802	ENOG4105FKZ	Methyl-accepting chemotaxis
TC41_2803	ENOG4107QTZ	amino acid
TC41_2804	ENOG4105C26	Dehydrogenase
TC41_2808	ENOG4107TVC	Glycosyl transferase, family 2
TC41_2810	ENOG4105DND	Transcriptional regulator
TC41_2814	ENOG4105CPQ	Dehydrogenase
TC41_2816	ENOG4105D3R	alkyl hydroperoxide reductase
TC41_2817	ENOG4105G5W	regulator Fur family
TC41_2818	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_2820	ENOG4105C85	amino acid
TC41_2822	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TC41_2823	ENOG4105CQB	FAD linked oxidase domain protein
TC41_2824	ENOG4108I5G	Major Facilitator superfamily
TC41_2825	ENOG4105E5G	Alpha beta hydrolase fold
TC41_2827	ENOG4105DAA	L-lactate
TC41_2829	ENOG4107QP3	malate synthase g
TC41_2830	ENOG4107HP6	Transcriptional regulator
TC41_2831	ENOG4105CQB	FAD linked oxidase domain protein
TC41_2832	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
TC41_2833	ENOG4105CQB	FAD linked oxidase domain protein
TC41_2834	ENOG4105CND	Glycosyl transferase, family 2
TC41_2842	ENOG4107XCH	Cyclase family
TC41_2843	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
TC41_2844	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
TC41_2846	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
TC41_2847	ENOG4105MS2	ribosomal subunit Interface protein
TC41_2848	ENOG4105CPK	Glycosyl transferase (Group 1
TC41_2851	ENOG4107TVC	Glycosyl transferase, family 2
TC41_2854	ENOG4105I03	Flagellin
TC41_2861	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
TC41_2862	ENOG4105BZU	Histidine kinase
TC41_2863	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
TC41_2866	ENOG4105WH1	Two component transcriptional regulator luxr family
TC41_2867	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
TC41_2871	ENOG4105C6X	Major Facilitator
TC41_2873	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
TC41_2874	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
TC41_2875	ENOG4105II7	pyrroline-5-carboxylate reductase
TC41_2876	ENOG4107XM9	(LipO)protein
TC41_2879	ENOG4105JAB	phenazine biosynthesis protein, phzf family
TC41_2888	ENOG4105ETE	Transcriptional regulator (LacI family
TC41_2890	ENOG4105CPC	Aldo Keto reductase
TC41_2891	ENOG4107QIV	Cytochrome c biogenesis protein
TC41_2892	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TC41_2896	ENOG41081YB	ApbE family
TC41_2900	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TC41_2901	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
TC41_2902	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
TC41_2905	ENOG4107RCC	Major Facilitator Superfamily
TC41_2907	ENOG4105N80	Ferric uptake regulator, Fur family
TC41_2908	ENOG4105DSE	periplasmic solute binding protein
TC41_2910	ENOG4105CC5	ABC transporter
TC41_2912	ENOG4108S4H	thioesterase Superfamily protein
TC41_2916	ENOG4105BZU	Histidine kinase
TC41_2917	ENOG4105D9R	oxidoreductase
TC41_2918	ENOG4107RGD	Major Facilitator superfamily
TC41_2921	ENOG4108T5E	Copper resistance protein
TC41_2922	ENOG4105KTB	nuclear export factor GLE1
TC41_2923	ENOG4105CJ3	phosphate transporter
TC41_2927	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
TC41_2928	ENOG4105DRS	transport system, permease
TC41_2930	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
TC41_2933	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
TC41_2936	ENOG4105DU6	RNA polymerase
TC41_2941	ENOG4105VPX	protein, conserved in bacteria
TC41_2943	ENOG4107TPS	domain protein
TC41_2944	ENOG4105VFE	sira family
TC41_2946	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
TC41_2948	ENOG41087NI	Sulfite exporter TauE/SafE
TC41_2953	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
TC41_2954	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
TC41_2960	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
TC41_2963	ENOG4105DFE	Dna adenine methylase
TC41_2965	ENOG4105VPX	protein, conserved in bacteria
TC41_2967	ENOG4108ZSR	alkaline shock protein
TC41_2971	ENOG4108ZAA	Alkaline-shock protein
TC41_2972	ENOG4108ZB6	transcriptional regulator AsnC family
TC41_2973	ENOG4105CHM	Aminotransferase
TC41_2974	ENOG4105DJB	Major Facilitator Superfamily
TC41_2975	ENOG4105DQ4	alcohol dehydrogenase
TC41_2976	ENOG4105ST3	Transcriptional regulator
TC41_2977	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
TC41_2979	ENOG4105E5H	Transposase
TC41_2982	ENOG4107SJI	Dehydrogenase
TC41_2986	ENOG4105E5H	Transposase
TC41_2988	ENOG4105D5G	Transposase
TC41_2997	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TC41_2998	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TC41_3000	ENOG4107U5W	ybbr family
TC41_3001	ENOG4105C8B	TIGR00159 family
TC41_3002	ENOG4108NMV	polysaccharide deacetylase
TC41_3005	ENOG4105D1F	ATP-binding protein
TC41_3008	ENOG4108UJD	30S ribosomal protein S9
TC41_3009	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TC41_3010	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TC41_3011	ENOG4108ZT0	50S ribosomal protein l17
TC41_3012	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TC41_3013	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TC41_3014	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TC41_3015	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TC41_3016	ENOG41067V7	50S ribosomal protein L36
TC41_3017	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
TC41_3019	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TC41_3020	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
TC41_3021	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TC41_3022	ENOG4105VPB	50S ribosomal protein L30
TC41_3023	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TC41_3025	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TC41_3026	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
TC41_3027	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TC41_3028	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
TC41_3029	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TC41_3030	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
TC41_3031	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TC41_3032	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TC41_3033	ENOG41082SA	50s ribosomal protein l29
TC41_3034	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
TC41_3035	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TC41_3037	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TC41_3038	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TC41_3039	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TC41_3040	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
TC41_3041	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TC41_3042	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TC41_3043	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TC41_3044	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TC41_3046	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
TC41_3047	ENOG4105XPM	ribosomal protein
TC41_3048	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TC41_3049	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TC41_3050	ENOG4107Y49	methyltransferase
TC41_3051	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
TC41_3052	ENOG4108VZM	50s ribosomal protein L10
TC41_3053	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TC41_3054	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TC41_3055	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
TC41_3057	ENOG4105WDJ	50S ribosomal protein L33
TC41_3058	ENOG4105QIV	RNA polymerase
TC41_3060	ENOG4105C2N	RNA methyltransferase TrmH family group 3
TC41_3061	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
TC41_3062	ENOG4105C8N	cysteinyl-tRNA synthetase
TC41_3063	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
TC41_3064	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
TC41_3065	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
TC41_3066	ENOG4105CTP	PilT protein domain protein
TC41_3067	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
TC41_3068	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
TC41_3069	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
TC41_3070	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TC41_3071	ENOG41066A3	ATP guanido phosphotransferase
TC41_3072	ENOG4108Z0C	Uvrb UvrC protein
TC41_3079	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
TC41_3080	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
TC41_3081	ENOG4108JQA	flagellar
TC41_3084	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
TC41_3085	ENOG4105FRN	stage II sporulation protein
TC41_3087	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TC41_3091	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TC41_3092	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
TC41_3093	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
TC41_3094	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
TC41_3095	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TC41_3096	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
TC41_3098	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
TC41_3101	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
TC41_3102	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
TC41_3103	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
TC41_3104	ENOG4108UIC	UPF0340 protein
TC41_3109	ENOG4105XPP	Protein of unknown function (DUF1275)
TC41_3113	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TC41_3114	ENOG4108ZXQ	stage ii sporulation protein r
TC41_3115	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
TC41_3116	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
TC41_3117	ENOG41082DI	50s ribosomal protein l31
TC41_3120	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
TC41_3122	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
TC41_3124	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TC41_3126	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
TC41_3127	ENOG4105E39	Enoyl-CoA hydratase
TC41_3128	ENOG4105E7W	lamb ycsf family protein
TC41_3130	ENOG4105P4J	Allophanate hydrolase, subunit 1
TC41_3131	ENOG4105K64	Glycosyl transferase, family 2
TC41_3133	ENOG4105CYW	agmatinase
TC41_3134	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
TC41_3135	ENOG4105C1G	acyl-Coa dehydrogenase
TC41_3137	ENOG4105BZ4	penicillin-binding protein
TC41_3144	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TC41_3145	ENOG4108Z5K	methylglyoxal synthase
TC41_3147	ENOG4107RAQ	aminopeptidase
TC41_3154	ENOG4105CMG	Carbohydrate kinase
TC41_3163	ENOG4105EUJ	GTP cyclohydrolase i
TC41_3165	ENOG4105FE1	phytoene synthase
TC41_3169	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
TC41_3174	ENOG4106DF1	
TC41_3180	ENOG4108M60	Transcriptional regulator
TC41_3182	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
TC41_3183	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
TC41_3184	ENOG4105CH2	amidohydrolase
TC41_3186	ENOG4105CHM	Aminotransferase
TC41_3190	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TC41_3191	ENOG4108IJ6	ABC transporter
TC41_3192	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TC41_3193	ENOG4105ECW	sulfate abc transporter
TC41_3194	ENOG4108Z6Z	Transcriptional regulator
TC41_3195	ENOG4105C1G	acyl-Coa dehydrogenase
TC41_3196	ENOG4105CEY	Amp-dependent synthetase and ligase
TC41_3197	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
TC41_3199	ENOG4105C4B	ABC transporter, permease
TC41_3200	ENOG4108IXI	(ABC) transporter
TC41_3201	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
TC41_3206	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
TC41_3209	ENOG4105BZU	Histidine kinase
TC41_3213	ENOG4105FKQ	transcriptional regulator
TC41_3214	ENOG4105EG2	ABC transporter, permease
TC41_3216	ENOG4107FKK	extracellular solute-binding protein family 1
TC41_3219	ENOG4105EUB	pirin domain protein
TC41_3220	ENOG41081VB	Hydrolase
TC41_3223	ENOG41079KZ	Major Facilitator Superfamily
TC41_3226	ENOG4105D7V	transposase
TC41_3233	ENOG4105DTT	CRISPR-associated helicase, cas3
TC41_3239	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
TC41_3240	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
TC41_3242	ENOG4105CJQ	hydrolase, family 31
TC41_3243	ENOG4108U51	Universal stress protein
TC41_3244	ENOG4108J59	Extracellular solute-binding protein, family 5
TC41_3245	ENOG4107XVH	Transcriptional regulator
TC41_3246	ENOG4105C4C	beta-galactosidase
TC41_3248	ENOG4108YZA	Nitrogen regulatory protein pii
TC41_3256	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
TC41_3257	ENOG4105DRS	transport system, permease
TC41_3262	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
TC41_3264	ENOG4105EF1	ribulokinase
TC41_3267	ENOG4105CMD	Transcriptional regulator, GntR family
TC41_3271	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TC41_3272	ENOG4105CW7	secretion protein, HlyD family
TC41_3273	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TC41_3274	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
TC41_3275	ENOG4105BZU	Histidine kinase
TC41_3277	ENOG4105DUM	transcriptional regulator, lysR family
TC41_3279	ENOG4105C0H	protease
TC41_3280	ENOG4105Q2H	domain protein
TC41_3283	ENOG4105BZU	Histidine kinase
TC41_3284	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TC41_3286	ENOG4105CDU	Replicative dna helicase
TC41_3287	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
TC41_3289	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
TC41_3290	ENOG4108UUM	single-stranded DNA-binding protein
TC41_3291	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
TC41_3292	ENOG4105C3G	gtp-binding protein
TC41_3293	ENOG4108J2R	molybdopterin oxidoreductase
TC41_3294	ENOG4105VDK	protein, conserved in bacteria
TC41_3295	ENOG4105D8X	mechanosensitive ion channel
TC41_3297	ENOG4108ZDA	Sporulation protein YyaC
TC41_3299	ENOG4108UQV	Membrane
TC41_3300	ENOG4105FA0	parb-like partition protein
TC41_3301	ENOG4107QJE	Chromosome Partitioning Protein
TC41_3303	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
TC41_3304	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TC41_3305	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
TC41_3306	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
TC41_3308	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
TC41_3310	ENOG4105VG0	50S ribosomal protein l34