locus-tag	class	description
NZD86_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NZD86_00010	COG0592	DNA-directed DNA polymerase activity
NZD86_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NZD86_00025	COG0187	DNA topoisomerase II activity
NZD86_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NZD86_00035	COG3842	ATPase activity
NZD86_00080	COG0516	GMP reductase activity
NZD86_00080	COG0517	IMP dehydrogenase activity
NZD86_00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NZD86_00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NZD86_00110	COG4974	Belongs to the 'phage' integrase family
NZD86_00245	COG0084	hydrolase, TatD family'
NZD86_00250	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_00265	COG1609	Transcriptional regulator
NZD86_00270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NZD86_00275	COG0366	Alpha amylase catalytic
NZD86_00290	COG1175	transmembrane transport
NZD86_00295	COG0395	ABC-type sugar transport system, permease component
NZD86_00300	COG0657	acetylesterase activity
NZD86_00355	COG2814	Major facilitator Superfamily
NZD86_00365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NZD86_00400	COG1250	3-hydroxyacyl-CoA dehydrogenase
NZD86_00400	COG0824	Thioesterase
NZD86_00410	COG2113	Glycine betaine
NZD86_00415	COG0583	DNA-binding transcription factor activity
NZD86_00420	COG0163	prenyltransferase activity
NZD86_00425	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NZD86_00440	COG1012	belongs to the aldehyde dehydrogenase family
NZD86_00445	COG0840	transmembrane signaling receptor activity
NZD86_00455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NZD86_00460	COG1802	Transcriptional regulator
NZD86_00465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NZD86_00505	COG0235	Class ii aldolase
NZD86_00510	COG1063	alcohol dehydrogenase
NZD86_00515	COG1850	ribulose-bisphosphate carboxylase activity
NZD86_00520	COG2271	Major facilitator Superfamily
NZD86_00530	COG0840	transmembrane signaling receptor activity
NZD86_00545	COG2508	Transcriptional regulator
NZD86_00550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NZD86_00570	COG0778	Nitroreductase
NZD86_00590	COG0179	Fumarylacetoacetate (FAA) hydrolase
NZD86_00595	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_00605	COG0697	spore germination
NZD86_00625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NZD86_00640	COG1132	(ABC) transporter
NZD86_00650	COG1846	Transcriptional regulator
NZD86_00675	COG0583	DNA-binding transcription factor activity
NZD86_00680	COG0477	Major facilitator Superfamily
NZD86_00700	COG4569	acetaldehyde dehydrogenase (acetylating) activity
NZD86_00715	COG2814	Major facilitator Superfamily
NZD86_00730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NZD86_00735	COG1024	Enoyl-CoA hydratase
NZD86_00745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NZD86_00750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NZD86_00770	COG1953	Uracil, thiamine, allantoin
NZD86_00790	COG2176	DNA-directed DNA polymerase activity
NZD86_00795	COG2508	Transcriptional regulator
NZD86_01000	COG0840	transmembrane signaling receptor activity
NZD86_01010	COG2814	Major facilitator Superfamily
NZD86_01030	COG0471	metal ion transport
NZD86_01030	COG3273	potassium ion transport
NZD86_01040	COG0281	malic enzyme
NZD86_01075	COG2186	Transcriptional regulator
NZD86_01080	COG0277	FAD linked oxidase domain protein
NZD86_01085	COG0247	lactate metabolic process
NZD86_01095	COG1472	Belongs to the glycosyl hydrolase 3 family
NZD86_01100	COG1737	Transcriptional regulator
NZD86_01105	COG0747	negative chemotaxis
NZD86_01110	COG0601	transmembrane transport
NZD86_01115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NZD86_01120	COG0444	Belongs to the ABC transporter superfamily
NZD86_01125	COG4608	Belongs to the ABC transporter superfamily
NZD86_01130	COG3876	Protein conserved in bacteria
NZD86_01145	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NZD86_01150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NZD86_01155	COG2971	BadF BadG BcrA BcrD
NZD86_01170	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_01210	COG0477	Major facilitator Superfamily
NZD86_01220	COG0640	Transcriptional regulator
NZD86_01240	COG1914	H( )-stimulated, divalent metal cation uptake system
NZD86_01250	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NZD86_01255	COG1164	Oligoendopeptidase f
NZD86_01265	COG2233	PERMEase
NZD86_01280	COG0596	Alpha beta hydrolase
NZD86_01315	COG2309	aminopeptidase activity
NZD86_01325	COG1113	amino acid transport
NZD86_01335	COG3579	cysteine-type endopeptidase activity
NZD86_01345	COG4221	oxidoreductase activity
NZD86_01370	COG0071	Belongs to the small heat shock protein (HSP20) family
NZD86_01400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NZD86_01405	COG1464	Belongs to the NlpA lipoprotein family
NZD86_01410	COG1435	thymidine kinase activity
NZD86_01415	COG0706	membrane insertase activity
NZD86_01415	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
NZD86_01460	COG1940	carbohydrate kinase activity
NZD86_01465	COG4213	ABC transporter substrate-binding protein
NZD86_01475	COG4214	carbohydrate transport
NZD86_01480	COG2309	aminopeptidase activity
NZD86_01505	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NZD86_01520	COG2176	DNA-directed DNA polymerase activity
NZD86_01540	COG1278	Cold shock
NZD86_01545	COG0405	Gamma-glutamyltransferase
NZD86_01550	COG2059	Chromate
NZD86_01555	COG2059	Chromate
NZD86_01560	COG1309	transcriptional regulator
NZD86_01565	COG1511	domain protein
NZD86_01570	COG3973	AAA domain
NZD86_01580	COG2154	pterin-4-alpha-carbinolamine dehydratase
NZD86_01585	COG0420	3'-5' exonuclease activity
NZD86_01590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NZD86_01595	COG0406	alpha-ribazole phosphatase activity
NZD86_01610	COG1940	carbohydrate kinase activity
NZD86_01660	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NZD86_01665	COG1850	ribulose-bisphosphate carboxylase activity
NZD86_01670	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NZD86_01675	COG0235	Class ii aldolase
NZD86_01680	COG1615	UPF0182 protein
NZD86_01690	COG1247	-acetyltransferase
NZD86_01695	COG2318	DinB family
NZD86_01710	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_01740	COG2132	Multicopper oxidase
NZD86_01745	COG0367	asparagine synthase
NZD86_01760	COG0590	tRNA wobble adenosine to inosine editing
NZD86_01770	COG3852	Histidine kinase
NZD86_01775	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NZD86_01780	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NZD86_01785	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NZD86_01800	COG2244	polysaccharide biosynthetic process
NZD86_01815	COG1982	Orn Lys Arg decarboxylase major
NZD86_01820	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NZD86_01825	COG3870	Protein conserved in bacteria
NZD86_01830	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NZD86_01840	COG4467	Involved in initiation control of chromosome replication
NZD86_01845	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NZD86_01850	COG2002	toxin-antitoxin pair type II binding
NZD86_01855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NZD86_01855	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NZD86_01860	COG0084	hydrolase, TatD family'
NZD86_01865	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NZD86_01870	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NZD86_01890	COG4466	Protein conserved in bacteria
NZD86_01905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NZD86_01905	COG0189	ligase activity
NZD86_01910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NZD86_01915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NZD86_01920	COG0251	oxidation-reduction process
NZD86_01930	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NZD86_01935	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NZD86_01940	COG0193	aminoacyl-tRNA hydrolase activity
NZD86_01950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NZD86_01955	COG2002	toxin-antitoxin pair type II binding
NZD86_01960	COG2244	polysaccharide biosynthetic process
NZD86_01965	COG3956	TIGRFAM MazG family protein
NZD86_01970	COG0776	regulation of translation
NZD86_01975	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NZD86_01995	COG1098	S1 RNA binding domain
NZD86_02015	COG2131	deaminase
NZD86_02020	COG2208	phosphoserine phosphatase activity
NZD86_02025	COG2304	oxidoreductase activity
NZD86_02035	COG0037	tRNA processing
NZD86_02035	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NZD86_02045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NZD86_02055	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NZD86_02060	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NZD86_02065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NZD86_02070	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NZD86_02075	COG1396	sequence-specific DNA binding
NZD86_02080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NZD86_02085	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NZD86_02110	COG0789	Transcriptional regulator
NZD86_02120	COG1664	Polymer-forming cytoskeletal
NZD86_02125	COG2814	Major facilitator Superfamily
NZD86_02130	COG1309	transcriptional regulator
NZD86_02135	COG4463	regulation of RNA biosynthetic process
NZD86_02140	COG3880	PFAM UvrB UvrC protein
NZD86_02145	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NZD86_02150	COG0542	response to heat
NZD86_02155	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NZD86_02160	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NZD86_02165	COG1183	phosphatidylcholine synthase activity
NZD86_02170	COG4956	integral membrane protein (PIN domain superfamily)
NZD86_02175	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NZD86_02180	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NZD86_02185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NZD86_02190	COG0215	cysteine-tRNA ligase activity
NZD86_02200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NZD86_02215	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NZD86_02225	COG0250	Participates in transcription elongation, termination and antitermination
NZD86_02235	COG0081	regulation of translation
NZD86_02240	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NZD86_02245	COG0222	ribosome binding
NZD86_02250	COG2813	Specifically methylates the guanine in position
NZD86_02255	COG0085	RNA polymerase activity
NZD86_02260	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NZD86_02265	COG1358	cellular component organization or biogenesis
NZD86_02270	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NZD86_02275	COG0049	tRNA binding
NZD86_02280	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NZD86_02290	COG0051	transcription antitermination factor activity, RNA binding
NZD86_02295	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NZD86_02305	COG0089	rRNA binding
NZD86_02310	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NZD86_02315	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NZD86_02320	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NZD86_02325	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NZD86_02330	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NZD86_02335	COG0255	Belongs to the universal ribosomal protein uL29 family
NZD86_02345	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NZD86_02350	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NZD86_02355	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NZD86_02360	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NZD86_02365	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NZD86_02370	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NZD86_02375	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NZD86_02380	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NZD86_02390	COG0200	Binds to the 23S rRNA
NZD86_02395	COG0201	protein transport
NZD86_02400	COG0563	adenylate kinase activity
NZD86_02410	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NZD86_02415	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NZD86_02420	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NZD86_02425	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NZD86_02430	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NZD86_02435	COG0202	RNA polymerase activity
NZD86_02440	COG0203	ribosomal protein L17
NZD86_02445	COG0101	tRNA pseudouridine synthase activity
NZD86_02450	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NZD86_02455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NZD86_02460	COG0860	N-Acetylmuramoyl-L-alanine amidase
NZD86_02470	COG0489	protein tyrosine kinase activity
NZD86_02480	COG0726	polysaccharide deacetylase
NZD86_02500	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NZD86_02505	COG4856	YbbR-like protein
NZD86_02510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NZD86_02555	COG0243	molybdopterin cofactor binding
NZD86_02595	COG0672	)-iron permease
NZD86_02600	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NZD86_02630	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_02645	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_02655	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_02660	COG0583	DNA-binding transcription factor activity
NZD86_02665	COG0789	Transcriptional regulator
NZD86_02670	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_02685	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NZD86_02705	COG0789	Transcriptional regulator
NZD86_02710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NZD86_02715	COG0596	Alpha beta hydrolase
NZD86_02715	COG2945	thiolester hydrolase activity
NZD86_02720	COG0456	acetyltransferase
NZD86_02740	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_02765	COG1309	transcriptional regulator
NZD86_02770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NZD86_02780	COG1960	acyl-CoA dehydrogenase activity
NZD86_02790	COG2030	dehydratase
NZD86_02805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NZD86_02825	COG2271	Major facilitator Superfamily
NZD86_02870	COG1378	Sugar-specific transcriptional regulator TrmB
NZD86_02875	COG0697	spore germination
NZD86_02930	COG0300	oxidoreductase activity
NZD86_02975	COG1278	Cold shock
NZD86_02985	COG3239	Fatty acid desaturase
NZD86_03000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NZD86_03010	COG1086	Polysaccharide biosynthesis protein
NZD86_03020	COG0438	transferase activity, transferring glycosyl groups
NZD86_03055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NZD86_03100	COG4086	secreted protein
NZD86_03105	COG5002	protein histidine kinase activity
NZD86_03125	COG0531	amino acid
NZD86_03130	COG2814	Major facilitator Superfamily
NZD86_03160	COG3832	glyoxalase III activity
NZD86_03170	COG2226	methyltransferase
NZD86_03180	COG2318	DinB family
NZD86_03200	COG1802	Transcriptional regulator
NZD86_03210	COG2807	transmembrane transport
NZD86_03215	COG0840	transmembrane signaling receptor activity
NZD86_03240	COG0667	Aldo Keto reductase
NZD86_03250	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_03255	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_03260	COG1733	regulation of RNA biosynthetic process
NZD86_03265	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_03275	COG0693	protein deglycase activity
NZD86_03285	COG0583	DNA-binding transcription factor activity
NZD86_03290	COG3135	benzoate transporter
NZD86_03295	COG0564	pseudouridine synthase activity
NZD86_03300	COG1271	oxidase subunit
NZD86_03305	COG1294	oxidase, subunit
NZD86_03310	COG4846	Membrane protein involved in cytochrome C biogenesis
NZD86_03315	COG2329	Antibiotic biosynthesis monooxygenase
NZD86_03325	COG3384	dioxygenase
NZD86_03330	COG0655	NAD(P)H dehydrogenase (quinone) activity
NZD86_03335	COG1733	regulation of RNA biosynthetic process
NZD86_03350	COG1227	inorganic diphosphatase activity
NZD86_03375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NZD86_03390	COG0243	molybdopterin cofactor binding
NZD86_03395	COG0737	Belongs to the 5'-nucleotidase family
NZD86_03400	COG1653	transport
NZD86_03405	COG1175	transmembrane transport
NZD86_03410	COG0395	ABC-type sugar transport system, permease component
NZD86_03415	COG0477	Major facilitator Superfamily
NZD86_03420	COG0583	DNA-binding transcription factor activity
NZD86_03430	COG2814	Major facilitator Superfamily
NZD86_03435	COG1278	Cold shock
NZD86_03440	COG0318	PFAM AMP-dependent synthetase and ligase
NZD86_03460	COG0534	Mate efflux family protein
NZD86_03465	COG2814	Major facilitator Superfamily
NZD86_03470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NZD86_03485	COG2814	Major facilitator Superfamily
NZD86_03490	COG0318	PFAM AMP-dependent synthetase and ligase
NZD86_03495	COG1525	nuclease
NZD86_03500	COG2205	protein histidine kinase activity
NZD86_03505	COG1113	amino acid transport
NZD86_03510	COG1053	succinate dehydrogenase
NZD86_03510	COG3976	FMN-binding domain protein
NZD86_03525	COG2340	Cysteine-rich secretory protein family
NZD86_03550	COG0833	amino acid
NZD86_03555	COG1392	Phosphate transport regulator
NZD86_03560	COG0306	phosphate transporter
NZD86_03575	COG0601	transmembrane transport
NZD86_03590	COG4608	Belongs to the ABC transporter superfamily
NZD86_03595	COG2723	6-phospho-beta-galactosidase activity
NZD86_03635	COG2271	Major facilitator Superfamily
NZD86_03640	COG0473	3-isopropylmalate dehydrogenase activity
NZD86_03640	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NZD86_03645	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NZD86_03650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NZD86_03675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NZD86_03685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NZD86_03695	COG2721	sulfolactate sulfo-lyase activity
NZD86_03715	COG2258	MOSC domain
NZD86_03725	COG1187	pseudouridine synthase activity
NZD86_03730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NZD86_03740	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NZD86_03745	COG0384	phenazine biosynthesis protein PhzF
NZD86_03850	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NZD86_03860	COG0833	amino acid
NZD86_03890	COG0456	acetyltransferase
NZD86_03895	COG0174	glutamine synthetase
NZD86_03905	COG0494	nUDIX hydrolase
NZD86_03910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NZD86_03915	COG0521	Mo-molybdopterin cofactor biosynthetic process
NZD86_03930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NZD86_03935	COG2814	Major facilitator Superfamily
NZD86_03950	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NZD86_03955	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NZD86_03960	COG2197	response regulator
NZD86_03975	COG0745	RESPONSE REGULATOR receiver
NZD86_03980	COG5002	protein histidine kinase activity
NZD86_03985	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NZD86_03995	COG1191	sigma factor activity
NZD86_04010	COG1256	bacterial-type flagellum assembly
NZD86_04010	COG4786	Flagellar basal body rod
NZD86_04020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NZD86_04025	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NZD86_04045	COG0463	Glycosyl transferase, family 2
NZD86_04045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NZD86_04050	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NZD86_04075	COG0110	maltose O-acetyltransferase activity
NZD86_04085	COG0457	Tetratricopeptide repeat
NZD86_04085	COG0463	Glycosyl transferase, family 2
NZD86_04095	COG0463	Glycosyl transferase, family 2
NZD86_04110	COG3436	PFAM IS66 Orf2 family protein
NZD86_04150	COG0653	protein targeting
NZD86_04165	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NZD86_04170	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NZD86_04175	COG0745	RESPONSE REGULATOR receiver
NZD86_04180	COG2205	protein histidine kinase activity
NZD86_04185	COG1136	(ABC) transporter
NZD86_04190	COG0577	efflux transmembrane transporter activity
NZD86_04215	COG2814	Major facilitator Superfamily
NZD86_04220	COG2814	Major facilitator Superfamily
NZD86_04235	COG2966	Psort location CytoplasmicMembrane, score
NZD86_04245	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NZD86_04250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NZD86_04255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NZD86_04260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NZD86_04265	COG3279	Response regulator of the LytR AlgR family
NZD86_04270	COG0427	acetyl-CoA hydrolase
NZD86_04275	COG1902	pentaerythritol trinitrate reductase activity
NZD86_04315	COG3104	oligopeptide transport
NZD86_04335	COG1132	(ABC) transporter
NZD86_04350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NZD86_04365	COG1725	Transcriptional regulator
NZD86_04370	COG1131	(ABC) transporter
NZD86_04380	COG1695	Transcriptional regulator
NZD86_04385	COG0697	spore germination
NZD86_04435	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NZD86_04455	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NZD86_04485	COG3328	transposase activity
NZD86_04495	COG1595	DNA-templated transcription, initiation
NZD86_04505	COG0835	chemotaxis
NZD86_04515	COG0154	amidase activity
NZD86_04555	COG4191	Histidine kinase
NZD86_04585	COG4585	Histidine kinase
NZD86_04595	COG2197	response regulator
NZD86_04600	COG3835	regulator
NZD86_04605	COG1929	Belongs to the glycerate kinase type-1 family
NZD86_04610	COG2610	gluconate transmembrane transporter activity
NZD86_04645	COG1396	sequence-specific DNA binding
NZD86_04665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NZD86_04670	COG1363	Peptidase, m42
NZD86_04680	COG1566	PFAM secretion protein HlyD family protein
NZD86_04685	COG2814	Major facilitator Superfamily
NZD86_04690	COG0655	NAD(P)H dehydrogenase (quinone) activity
NZD86_04710	COG0386	Belongs to the glutathione peroxidase family
NZD86_04730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NZD86_04730	COG1648	precorrin-2 dehydrogenase activity
NZD86_04735	COG0175	sulfate reduction
NZD86_04740	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NZD86_04745	COG1587	Uroporphyrinogen-III synthase
NZD86_04745	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NZD86_04755	COG4841	protein insertion into membrane
NZD86_04775	COG0788	formyltetrahydrofolate deformylase activity
NZD86_04780	COG2124	cytochrome p450
NZD86_04790	COG1335	isochorismatase
NZD86_04795	COG0531	amino acid
NZD86_04800	COG1304	FMN binding
NZD86_04805	COG2814	Major facilitator Superfamily
NZD86_04815	COG0583	DNA-binding transcription factor activity
NZD86_04890	COG5002	protein histidine kinase activity
NZD86_04895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NZD86_04900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NZD86_04905	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_04915	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_04925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NZD86_04935	COG1657	PFAM Prenyltransferase squalene oxidase
NZD86_04950	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NZD86_04960	COG3829	transcription factor binding
NZD86_04965	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NZD86_04975	COG0318	PFAM AMP-dependent synthetase and ligase
NZD86_04980	COG0446	pyridine nucleotide-disulphide oxidoreductase
NZD86_04980	COG1902	pentaerythritol trinitrate reductase activity
NZD86_04990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NZD86_05005	COG1063	alcohol dehydrogenase
NZD86_05020	COG3852	Histidine kinase
NZD86_05030	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NZD86_05070	COG4496	protein, YerC YecD
NZD86_05085	COG1045	serine acetyltransferase
NZD86_05090	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NZD86_05090	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NZD86_05100	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NZD86_05100	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NZD86_05105	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NZD86_05115	COG2267	carboxylic ester hydrolase activity
NZD86_05120	COG2827	Endonuclease containing a URI domain
NZD86_05135	COG0579	oxidoreductase
NZD86_05145	COG3711	transcriptional antiterminator
NZD86_05160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NZD86_05180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NZD86_05205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NZD86_05220	COG1378	Sugar-specific transcriptional regulator TrmB
NZD86_05235	COG0477	Major facilitator Superfamily
NZD86_05265	COG3436	PFAM IS66 Orf2 family protein
NZD86_05295	COG0456	acetyltransferase
NZD86_05330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NZD86_05335	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NZD86_05345	COG1279	arginine transmembrane transporter activity
NZD86_05350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NZD86_05365	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NZD86_05375	COG2346	COG2346, Truncated hemoglobins
NZD86_05385	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NZD86_05400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NZD86_05405	COG1438	arginine binding
NZD86_05410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NZD86_05430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NZD86_05435	COG4109	DRTGG domain
NZD86_05440	COG0587	DNA-directed DNA polymerase activity
NZD86_05445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NZD86_05455	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NZD86_05460	COG0825	malonyl-CoA metabolic process
NZD86_05465	COG0469	pyruvate kinase activity
NZD86_05485	COG0180	Tryptophanyl-tRNA synthetase
NZD86_05490	COG0745	RESPONSE REGULATOR receiver
NZD86_05495	COG5002	protein histidine kinase activity
NZD86_05495	COG3850	Histidine kinase
NZD86_05500	COG0538	isocitrate dehydrogenase activity
NZD86_05515	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NZD86_05535	COG2188	Transcriptional regulator
NZD86_05540	COG1063	alcohol dehydrogenase
NZD86_05550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NZD86_05570	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NZD86_05575	COG1063	alcohol dehydrogenase
NZD86_05580	COG1063	alcohol dehydrogenase
NZD86_05595	COG1175	transmembrane transport
NZD86_05600	COG0395	ABC-type sugar transport system, permease component
NZD86_05605	COG1063	alcohol dehydrogenase
NZD86_05610	COG1349	DNA-binding transcription factor activity
NZD86_05625	COG0673	inositol 2-dehydrogenase activity
NZD86_05635	COG1349	DNA-binding transcription factor activity
NZD86_05645	COG1105	Belongs to the carbohydrate kinase PfkB family
NZD86_05650	COG1070	Carbohydrate kinase
NZD86_05665	COG1012	belongs to the aldehyde dehydrogenase family
NZD86_05670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NZD86_05685	COG2814	Major facilitator Superfamily
NZD86_05690	COG0583	DNA-binding transcription factor activity
NZD86_05700	COG4638	Rieske (2fe-2S)
NZD86_05710	COG0583	DNA-binding transcription factor activity
NZD86_05735	COG0235	Class ii aldolase
NZD86_05745	COG4948	Mandelate Racemase Muconate Lactonizing
NZD86_05760	COG2271	Major facilitator Superfamily
NZD86_05770	COG2843	Capsule synthesis protein
NZD86_05780	COG1506	peptidase
NZD86_05780	COG4946	Tricorn protease homolog
NZD86_05780	COG0823	Involved in the tonB-independent uptake of proteins
NZD86_05785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NZD86_05790	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NZD86_05795	COG0154	amidase activity
NZD86_05815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NZD86_05825	COG1012	belongs to the aldehyde dehydrogenase family
NZD86_05830	COG1454	alcohol dehydrogenase
NZD86_05870	COG1024	Enoyl-CoA hydratase
NZD86_05875	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NZD86_05885	COG0747	negative chemotaxis
NZD86_05895	COG1250	3-hydroxyacyl-CoA dehydrogenase
NZD86_05900	COG1960	acyl-CoA dehydrogenase activity
NZD86_05920	COG0681	Belongs to the peptidase S26 family
NZD86_05930	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_05935	COG1309	transcriptional regulator
NZD86_05940	COG0657	acetylesterase activity
NZD86_05950	COG1414	Transcriptional regulator
NZD86_05955	COG3385	transposase activity
NZD86_05960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NZD86_05965	COG4948	Mandelate Racemase Muconate Lactonizing
NZD86_05970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NZD86_05985	COG0800	Aldolase
NZD86_05990	COG1556	Lactate utilization protein
NZD86_05995	COG1139	Iron-sulfur cluster binding protein
NZD86_06000	COG0247	lactate metabolic process
NZD86_06005	COG2186	Transcriptional regulator
NZD86_06010	COG1070	Carbohydrate kinase
NZD86_06020	COG2721	sulfolactate sulfo-lyase activity
NZD86_06025	COG3718	enzyme involved in inositol metabolism
NZD86_06035	COG0246	Mannitol dehydrogenase
NZD86_06040	COG0251	oxidation-reduction process
NZD86_06060	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NZD86_06065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NZD86_06070	COG0640	Transcriptional regulator
NZD86_06080	COG1595	DNA-templated transcription, initiation
NZD86_06095	COG1414	Transcriptional regulator
NZD86_06105	COG1012	belongs to the aldehyde dehydrogenase family
NZD86_06130	COG4569	acetaldehyde dehydrogenase (acetylating) activity
NZD86_06145	COG1942	4-Oxalocrotonate Tautomerase
NZD86_06165	COG2814	Major facilitator Superfamily
NZD86_06185	COG1595	DNA-templated transcription, initiation
NZD86_06200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NZD86_06205	COG1012	belongs to the aldehyde dehydrogenase family
NZD86_06230	COG1376	ErfK ybiS ycfS ynhG family protein
NZD86_06250	COG1132	(ABC) transporter
NZD86_06255	COG1132	(ABC) transporter
NZD86_06260	COG1072	(Pantothenic acid kinase))
NZD86_06270	COG2390	Transcriptional regulator
NZD86_06280	COG4989	oxidoreductase activity
NZD86_06285	COG3290	protein histidine kinase activity
NZD86_06285	COG0840	transmembrane signaling receptor activity
NZD86_06290	COG3300	MHYT domain
NZD86_06290	COG5001	Diguanylate cyclase
NZD86_06300	COG0583	DNA-binding transcription factor activity
NZD86_06310	COG5002	protein histidine kinase activity
NZD86_06315	COG0095	Lipoate-protein ligase
NZD86_06320	COG5002	protein histidine kinase activity
NZD86_06325	COG0745	RESPONSE REGULATOR receiver
NZD86_06330	COG2814	Major facilitator Superfamily
NZD86_06335	COG0444	Belongs to the ABC transporter superfamily
NZD86_06340	COG4608	Belongs to the ABC transporter superfamily
NZD86_06345	COG0747	negative chemotaxis
NZD86_06350	COG0601	transmembrane transport
NZD86_06355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NZD86_06365	COG2155	Conserved Protein
NZD86_06370	COG1757	Na H antiporter
NZD86_06375	COG1132	(ABC) transporter
NZD86_06380	COG1132	(ABC) transporter
NZD86_06395	COG1388	LysM domain
NZD86_06395	COG3858	chitin binding
NZD86_06425	COG0640	Transcriptional regulator
NZD86_06430	COG0798	PFAM Bile acid sodium symporter
NZD86_06435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NZD86_06485	COG1595	DNA-templated transcription, initiation
NZD86_06490	COG0640	Transcriptional regulator
NZD86_06495	COG0492	ferredoxin-NADP+ reductase activity
NZD86_06550	COG1937	Protein conserved in bacteria
NZD86_06560	COG0346	lactoylglutathione lyase activity
NZD86_06565	COG0640	Transcriptional regulator
NZD86_06570	COG0640	Transcriptional regulator
NZD86_06575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NZD86_06580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NZD86_06590	COG0640	Transcriptional regulator
NZD86_06600	COG1971	Probably functions as a manganese efflux pump
NZD86_06640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NZD86_06640	COG1017	nitric oxide dioxygenase activity
NZD86_06645	COG1959	2 iron, 2 sulfur cluster binding
NZD86_06650	COG1940	carbohydrate kinase activity
NZD86_06660	COG1175	transmembrane transport
NZD86_06665	COG0395	ABC-type sugar transport system, permease component
NZD86_06680	COG0366	Alpha amylase catalytic
NZD86_06685	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NZD86_06700	COG0346	lactoylglutathione lyase activity
NZD86_06730	COG1607	acyl-coa hydrolase
NZD86_06740	COG1653	transport
NZD86_06760	COG0460	homoserine dehydrogenase
NZD86_06765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NZD86_06770	COG0129	dihydroxy-acid dehydratase activity
NZD86_06775	COG0028	Belongs to the TPP enzyme family
NZD86_06780	COG0440	acetolactate synthase activity
NZD86_06785	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NZD86_06790	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NZD86_06795	COG0473	3-isopropylmalate dehydrogenase activity
NZD86_06800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NZD86_06805	COG0066	3-isopropylmalate dehydratase activity
NZD86_06815	COG1971	Probably functions as a manganese efflux pump
NZD86_06820	COG0372	Belongs to the citrate synthase family
NZD86_06835	COG0517	IMP dehydrogenase activity
NZD86_06855	COG1136	(ABC) transporter
NZD86_06860	COG0577	efflux transmembrane transporter activity
NZD86_06865	COG0501	Belongs to the peptidase M48B family
NZD86_06875	COG0438	transferase activity, transferring glycosyl groups
NZD86_06885	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NZD86_06920	COG0640	Transcriptional regulator
NZD86_06965	COG1597	lipid kinase activity
NZD86_06975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NZD86_06995	COG0517	IMP dehydrogenase activity
NZD86_07000	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NZD86_07005	COG0574	Belongs to the PEP-utilizing enzyme family
NZD86_07005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NZD86_07010	COG0842	Transport permease protein
NZD86_07020	COG1131	(ABC) transporter
NZD86_07025	COG2197	response regulator
NZD86_07030	COG4585	Histidine kinase
NZD86_07045	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NZD86_07060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NZD86_07125	COG3409	Peptidoglycan-binding domain 1 protein
NZD86_07125	COG3757	hydrolase, family 25
NZD86_07210	COG3069	C4-dicarboxylate transmembrane transporter activity
NZD86_07220	COG2151	metal-sulfur cluster biosynthetic enzyme
NZD86_07245	COG0300	oxidoreductase activity
NZD86_07260	COG1846	Transcriptional regulator
NZD86_07265	COG2814	Major facilitator Superfamily
NZD86_07280	COG5002	protein histidine kinase activity
NZD86_07295	COG3385	transposase activity
NZD86_07300	COG3852	Histidine kinase
NZD86_07305	COG2211	Major facilitator Superfamily
NZD86_07355	COG1846	Transcriptional regulator
NZD86_07415	COG5609	conserved protein (DUF2294)
NZD86_07420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NZD86_07425	COG0569	domain protein
NZD86_07450	COG1285	pathogenesis
NZD86_07480	COG0840	transmembrane signaling receptor activity
NZD86_07485	COG0702	epimerase
NZD86_07500	COG0196	riboflavin kinase activity
NZD86_07510	COG0735	belongs to the Fur family
NZD86_07515	COG0450	alkyl hydroperoxide reductase
NZD86_07520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NZD86_07525	COG0431	NADPH-dependent FMN reductase
NZD86_07530	COG2259	Doxx family
NZD86_07545	COG2201	protein-glutamate methylesterase activity
NZD86_07565	COG3344	reverse transcriptase
NZD86_07575	COG5002	protein histidine kinase activity
NZD86_07580	COG2814	Major facilitator Superfamily
NZD86_07625	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NZD86_07630	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NZD86_07635	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NZD86_07640	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NZD86_07645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NZD86_07655	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NZD86_07660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NZD86_07680	COG3546	catalase activity
NZD86_07685	COG2259	Doxx family
NZD86_07705	COG0673	inositol 2-dehydrogenase activity
NZD86_07715	COG1940	carbohydrate kinase activity
NZD86_07720	COG0840	transmembrane signaling receptor activity
NZD86_07725	COG1720	tRNA m6t6A37 methyltransferase activity
NZD86_07740	COG0456	acetyltransferase
NZD86_07740	COG1846	Transcriptional regulator
NZD86_07745	COG0346	lactoylglutathione lyase activity
NZD86_07750	COG0400	carboxylic ester hydrolase activity
NZD86_07770	COG1595	DNA-templated transcription, initiation
NZD86_07775	COG0671	phosphoesterase, PA-phosphatase related
NZD86_07785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NZD86_07790	COG1482	cell wall glycoprotein biosynthetic process
NZD86_07805	COG0714	Associated with various cellular activities
NZD86_07815	COG0567	Dehydrogenase, E1 component
NZD86_07820	COG0508	dehydrogenase complex catalyzes the overall conversion of
NZD86_07830	COG1175	transmembrane transport
NZD86_07835	COG0395	ABC-type sugar transport system, permease component
NZD86_07855	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
NZD86_07860	COG2186	Transcriptional regulator
NZD86_07885	COG2211	Major facilitator Superfamily
NZD86_07890	COG0561	phosphatase activity
NZD86_07905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NZD86_07910	COG1388	LysM domain
NZD86_07910	COG3858	chitin binding
NZD86_07915	COG0584	glycerophosphoryl diester phosphodiesterase
NZD86_07930	COG2508	Transcriptional regulator
NZD86_07935	COG3842	ATPase activity
NZD86_07940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NZD86_07945	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NZD86_07950	COG0205	6-phosphofructokinase activity
NZD86_07955	COG1830	Aldolase
NZD86_07960	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NZD86_07965	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NZD86_07975	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NZD86_07980	COG0072	phenylalanine-tRNA ligase activity
NZD86_07980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NZD86_07985	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NZD86_08000	COG1193	negative regulation of DNA recombination
NZD86_08010	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_08015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NZD86_08025	COG3290	protein histidine kinase activity
NZD86_08025	COG0840	transmembrane signaling receptor activity
NZD86_08040	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NZD86_08040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NZD86_08050	COG0217	transcriptional regulatory protein
NZD86_08060	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NZD86_08065	COG0632	four-way junction helicase activity
NZD86_08070	COG2255	four-way junction helicase activity
NZD86_08075	COG1191	sigma factor activity
NZD86_08080	COG4447	cellulose binding
NZD86_08085	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NZD86_08105	COG3706	GGDEF domain
NZD86_08110	COG2323	membrane
NZD86_08115	COG2244	polysaccharide biosynthetic process
NZD86_08125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NZD86_08130	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NZD86_08135	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NZD86_08140	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NZD86_08140	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NZD86_08145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NZD86_08150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NZD86_08155	COG1490	D-aminoacyl-tRNA deacylase activity
NZD86_08160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NZD86_08170	COG0475	glutathione-regulated potassium exporter activity
NZD86_08170	COG0569	domain protein
NZD86_08175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NZD86_08190	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NZD86_08195	COG1725	Transcriptional regulator
NZD86_08200	COG1131	(ABC) transporter
NZD86_08210	COG0456	acetyltransferase
NZD86_08225	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NZD86_08230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NZD86_08235	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NZD86_08255	COG1686	Belongs to the peptidase S11 family
NZD86_08270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NZD86_08275	COG0681	Belongs to the peptidase S26 family
NZD86_08280	COG0477	Major facilitator Superfamily
NZD86_08290	COG4717	serine-type aminopeptidase activity
NZD86_08295	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NZD86_08300	COG1074	ATP-dependent DNA helicase activity
NZD86_08305	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NZD86_08310	COG4191	Histidine kinase
NZD86_08315	COG5002	protein histidine kinase activity
NZD86_08335	COG0189	ligase activity
NZD86_08340	COG0303	'Molybdopterin
NZD86_08345	COG0667	Aldo Keto reductase
NZD86_08360	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_08370	COG3595	metallopeptidase activity
NZD86_08380	COG1250	3-hydroxyacyl-CoA dehydrogenase
NZD86_08385	COG0039	L-malate dehydrogenase activity
NZD86_08390	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NZD86_08390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NZD86_08410	COG1131	(ABC) transporter
NZD86_08440	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NZD86_08455	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NZD86_08465	COG0840	transmembrane signaling receptor activity
NZD86_08475	COG1959	2 iron, 2 sulfur cluster binding
NZD86_08480	COG1104	cysteine desulfurase activity
NZD86_08490	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NZD86_08495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NZD86_08500	COG0628	permease
NZD86_08510	COG4472	Bacterial protein of unknown function (DUF965)
NZD86_08520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NZD86_08525	COG0768	penicillin binding
NZD86_08535	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NZD86_08550	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NZD86_08555	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NZD86_08560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NZD86_08565	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NZD86_08570	COG1713	HD superfamily hydrolase involved in NAD metabolism
NZD86_08575	COG0799	negative regulation of ribosome biogenesis
NZD86_08580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NZD86_08600	COG1252	NADH dehydrogenase
NZD86_08605	COG1466	dna polymerase III delta subunit
NZD86_08615	COG0268	Binds directly to 16S ribosomal RNA
NZD86_08620	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NZD86_08625	COG0372	Belongs to the citrate synthase family
NZD86_08630	COG0583	DNA-binding transcription factor activity
NZD86_08635	COG0741	lytic transglycosylase activity
NZD86_08650	COG0481	GTPase activity
NZD86_08655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NZD86_08660	COG1420	regulation of RNA biosynthetic process
NZD86_08665	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NZD86_08670	COG0443	Heat shock 70 kDa protein
NZD86_08680	COG2264	protein methyltransferase activity
NZD86_08685	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NZD86_08690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NZD86_08700	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NZD86_08705	COG1283	sodium-dependent phosphate transmembrane transporter activity
NZD86_08710	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NZD86_08715	COG1610	YqeY-like protein
NZD86_08730	COG1702	phosphate starvation-inducible protein PhoH
NZD86_08735	COG1480	7TM receptor with intracellular HD hydrolase
NZD86_08740	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NZD86_08750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NZD86_08765	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NZD86_08770	COG0358	DNA primase activity
NZD86_08775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NZD86_08785	COG2384	SAM-dependent methyltransferase
NZD86_08790	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NZD86_08830	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NZD86_08845	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NZD86_08890	COG1396	sequence-specific DNA binding
NZD86_08920	COG1388	LysM domain
NZD86_08920	COG1705	Flagellar rod assembly protein muramidase FlgJ
NZD86_08945	COG0305	Participates in initiation and elongation during chromosome replication
NZD86_09070	COG1802	Transcriptional regulator
NZD86_09070	COG4626	Terminase
NZD86_09075	COG4695	Portal protein
NZD86_09080	COG0740	serine-type endopeptidase activity
NZD86_09150	COG4824	toxin secretion phage lysis holin
NZD86_09240	COG2814	Major facilitator Superfamily
NZD86_09245	COG5002	protein histidine kinase activity
NZD86_09250	COG0316	Belongs to the HesB IscA family
NZD86_09255	COG1914	H( )-stimulated, divalent metal cation uptake system
NZD86_09270	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_09280	COG0582	viral genome integration into host DNA
NZD86_09290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NZD86_09305	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NZD86_09320	COG3858	chitin binding
NZD86_09320	COG1388	LysM domain
NZD86_09330	COG0693	protein deglycase activity
NZD86_09380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NZD86_09395	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NZD86_09405	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NZD86_09410	COG2205	protein histidine kinase activity
NZD86_09415	COG2205	protein histidine kinase activity
NZD86_09420	COG0745	RESPONSE REGULATOR receiver
NZD86_09425	COG2223	nitrite transmembrane transporter activity
NZD86_09445	COG0768	penicillin binding
NZD86_09490	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NZD86_09500	COG2211	Major facilitator Superfamily
NZD86_09510	COG1846	Transcriptional regulator
NZD86_09515	COG0477	Major facilitator Superfamily
NZD86_09520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NZD86_09525	COG0306	phosphate transporter
NZD86_09530	COG1131	(ABC) transporter
NZD86_09535	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NZD86_09560	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NZD86_09585	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NZD86_09595	COG0726	polysaccharide deacetylase
NZD86_09610	COG0602	queuosine metabolic process
NZD86_09615	COG0720	synthase
NZD86_09620	COG1733	regulation of RNA biosynthetic process
NZD86_09630	COG0778	Nitroreductase
NZD86_09640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NZD86_09645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NZD86_09650	COG1120	ATPase activity
NZD86_09655	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
NZD86_09660	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NZD86_09675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NZD86_09680	COG0439	Biotin carboxylase
NZD86_09685	COG0511	ligase activity, forming carbon-carbon bonds
NZD86_09690	COG1024	Enoyl-CoA hydratase
NZD86_09695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NZD86_09700	COG1960	acyl-CoA dehydrogenase activity
NZD86_09705	COG2030	dehydratase
NZD86_09710	COG1940	carbohydrate kinase activity
NZD86_09725	COG0531	amino acid
NZD86_09735	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NZD86_09745	COG2080	2 iron, 2 sulfur cluster binding
NZD86_09770	COG0697	spore germination
NZD86_09795	COG1924	4 iron, 4 sulfur cluster binding
NZD86_09810	COG4946	Tricorn protease homolog
NZD86_09810	COG1506	peptidase
NZD86_09810	COG0823	Involved in the tonB-independent uptake of proteins
NZD86_09815	COG1506	peptidase
NZD86_09815	COG4946	Tricorn protease homolog
NZD86_09815	COG0823	Involved in the tonB-independent uptake of proteins
NZD86_09875	COG3344	reverse transcriptase
NZD86_09910	COG0398	Pfam SNARE associated Golgi protein
NZD86_09915	COG4336	lyase activity
NZD86_09925	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NZD86_09930	COG1984	allophanate hydrolase subunit 2
NZD86_09935	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NZD86_09945	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NZD86_09950	COG2224	Isocitrate lyase
NZD86_09955	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NZD86_09960	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NZD86_09965	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NZD86_10015	COG1309	transcriptional regulator
NZD86_10030	COG1331	Highly conserved protein containing a thioredoxin domain
NZD86_10035	COG1331	Highly conserved protein containing a thioredoxin domain
NZD86_10045	COG2427	Protein of unknown function (DUF1641)
NZD86_10050	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NZD86_10070	COG0598	Magnesium transport protein CorA
NZD86_10075	COG1575	Belongs to the MenA family. Type 1 subfamily
NZD86_10080	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NZD86_10085	COG0318	PFAM AMP-dependent synthetase and ligase
NZD86_10095	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NZD86_10100	COG0596	Alpha beta hydrolase
NZD86_10125	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NZD86_10130	COG0726	polysaccharide deacetylase
NZD86_10140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NZD86_10145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NZD86_10150	COG0791	NLP P60 protein
NZD86_10150	COG1388	LysM domain
NZD86_10165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NZD86_10170	COG0456	acetyltransferase
NZD86_10185	COG1276	copper resistance
NZD86_10185	COG2372	response to copper ion
NZD86_10190	COG4549	nuclear export factor GLE1
NZD86_10205	COG1473	amidohydrolase
NZD86_10220	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NZD86_10225	COG0747	negative chemotaxis
NZD86_10240	COG0840	transmembrane signaling receptor activity
NZD86_10260	COG2002	toxin-antitoxin pair type II binding
NZD86_10280	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NZD86_10290	COG2076	Multidrug Resistance protein
NZD86_10315	COG2096	Adenosyltransferase
NZD86_10320	COG0647	UMP catabolic process
NZD86_10325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NZD86_10335	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_10345	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_10360	COG2003	Belongs to the UPF0758 family
NZD86_10375	COG4974	Belongs to the 'phage' integrase family
NZD86_10380	COG0582	viral genome integration into host DNA
NZD86_10385	COG4974	Belongs to the 'phage' integrase family
NZD86_10415	COG1070	Carbohydrate kinase
NZD86_10425	COG1349	DNA-binding transcription factor activity
NZD86_10430	COG1653	transport
NZD86_10435	COG1175	transmembrane transport
NZD86_10440	COG0395	ABC-type sugar transport system, permease component
NZD86_10450	COG3842	ATPase activity
NZD86_10455	COG1063	alcohol dehydrogenase
NZD86_10460	COG0698	ribose 5-phosphate isomerase
NZD86_10465	COG2376	Dihydroxyacetone kinase
NZD86_10475	COG0588	phosphoglycerate mutase activity
NZD86_10480	COG1070	Carbohydrate kinase
NZD86_10485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NZD86_10490	COG1349	DNA-binding transcription factor activity
NZD86_10495	COG0698	ribose 5-phosphate isomerase
NZD86_10505	COG3347	Dehydrogenase
NZD86_10505	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_10525	COG3344	reverse transcriptase
NZD86_10540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NZD86_10545	COG0697	spore germination
NZD86_10565	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_10580	COG2323	membrane
NZD86_10600	COG1940	carbohydrate kinase activity
NZD86_10605	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NZD86_10610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NZD86_10615	COG0166	Belongs to the GPI family
NZD86_10660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NZD86_10670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NZD86_10705	COG1846	Transcriptional regulator
NZD86_10715	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NZD86_10725	COG0463	Glycosyl transferase, family 2
NZD86_10730	COG1316	TRANSCRIPTIONal
NZD86_10750	COG0387	Pfam Sodium calcium exchanger
NZD86_10760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NZD86_10765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NZD86_10775	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NZD86_10800	COG0322	excinuclease ABC activity
NZD86_10805	COG2009	succinate dehydrogenase
NZD86_10810	COG1053	succinate dehydrogenase
NZD86_10815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NZD86_10830	COG0095	Lipoate-protein ligase
NZD86_10835	COG1054	Belongs to the UPF0176 family
NZD86_10840	COG2814	Major facilitator Superfamily
NZD86_10845	COG2188	Transcriptional regulator
NZD86_10865	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NZD86_10870	COG2197	response regulator
NZD86_10875	COG1846	Transcriptional regulator
NZD86_10880	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NZD86_10905	COG0544	peptidyl-prolyl cis-trans isomerase activity
NZD86_10910	COG0740	serine-type endopeptidase activity
NZD86_10915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NZD86_10920	COG0470	DNA polymerase III
NZD86_10920	COG1067	ATP-dependent peptidase activity
NZD86_10930	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NZD86_10935	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NZD86_10940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NZD86_10945	COG0181	hydroxymethylbilane synthase activity
NZD86_10955	COG0113	porphobilinogen synthase activity
NZD86_10960	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NZD86_10980	COG0525	valine-tRNA ligase activity
NZD86_10985	COG0285	dihydrofolate synthase activity
NZD86_10990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NZD86_11000	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NZD86_11005	COG3583	domain protein
NZD86_11005	COG3584	3D domain protein
NZD86_11010	COG3511	phospholipase C
NZD86_11015	COG2805	Type II/IV secretion system protein
NZD86_11030	COG2003	Belongs to the UPF0758 family
NZD86_11035	COG1077	Cell shape determining protein MreB Mrl
NZD86_11050	COG0850	regulation of cytokinetic process
NZD86_11055	COG2894	cell division
NZD86_11080	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NZD86_11090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NZD86_11100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NZD86_11135	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NZD86_11140	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NZD86_11150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NZD86_11155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NZD86_11160	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NZD86_11165	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NZD86_11170	COG0406	alpha-ribazole phosphatase activity
NZD86_11180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NZD86_11190	COG3854	ATPases associated with a variety of cellular activities
NZD86_11230	COG0511	ligase activity, forming carbon-carbon bonds
NZD86_11235	COG0439	Biotin carboxylase
NZD86_11240	COG1302	Protein conserved in bacteria
NZD86_11255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NZD86_11260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NZD86_11265	COG0492	ferredoxin-NADP+ reductase activity
NZD86_11270	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NZD86_11275	COG1570	exodeoxyribonuclease VII activity
NZD86_11280	COG1722	exodeoxyribonuclease VII activity
NZD86_11295	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NZD86_11300	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NZD86_11310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NZD86_11315	COG0497	DNA recombination
NZD86_11320	COG0750	zinc metalloprotease
NZD86_11435	COG3253	May function as heme-dependent peroxidase
NZD86_11465	COG0314	molybdopterin synthase activity
NZD86_11470	COG0315	cyclic pyranopterin monophosphate synthase activity
NZD86_11475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NZD86_11480	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NZD86_11485	COG0321	lipoyl(octanoyl) transferase activity
NZD86_11490	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NZD86_11490	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NZD86_11495	COG0346	lactoylglutathione lyase activity
NZD86_11500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NZD86_11505	COG2195	Cleaves the N-terminal amino acid of tripeptides
NZD86_11520	COG1379	DNA repair
NZD86_11525	COG1300	Membrane
NZD86_11540	COG4974	Belongs to the 'phage' integrase family
NZD86_11545	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NZD86_11550	COG1686	Belongs to the peptidase S11 family
NZD86_11560	COG1366	Belongs to the anti-sigma-factor antagonist family
NZD86_11565	COG2172	sigma factor antagonist activity
NZD86_11570	COG1191	sigma factor activity
NZD86_11580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NZD86_11600	COG1994	Peptidase M50
NZD86_11605	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NZD86_11610	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NZD86_11620	COG3874	Sporulation protein YtfJ
NZD86_11625	COG2715	membrane protein required for spore maturation
NZD86_11630	COG0700	Nucleoside recognition
NZD86_11635	COG1187	pseudouridine synthase activity
NZD86_11645	COG0745	RESPONSE REGULATOR receiver
NZD86_11650	COG5002	protein histidine kinase activity
NZD86_11665	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NZD86_11675	COG2339	peptidase activity
NZD86_11690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NZD86_11695	COG1054	Belongs to the UPF0176 family
NZD86_11705	COG2226	methyltransferase
NZD86_11715	COG1074	ATP-dependent DNA helicase activity
NZD86_11720	COG0582	viral genome integration into host DNA
NZD86_11745	COG3645	SOS response
NZD86_11745	COG3646	Phage regulatory protein
NZD86_11780	COG5377	YqaJ viral recombinase family
NZD86_11785	COG3723	Recombinational DNA repair protein, rece pathway
NZD86_11790	COG1388	LysM domain
NZD86_11930	COG3728	DNA packaging
NZD86_11935	COG1783	phage Terminase large subunit
NZD86_12045	COG0463	Glycosyl transferase, family 2
NZD86_12150	COG0210	DNA helicase
NZD86_12180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NZD86_12185	COG4862	establishment of competence for transformation
NZD86_12190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NZD86_12215	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NZD86_12225	COG0539	negative regulation of cytoplasmic translation
NZD86_12240	COG1160	GTP binding
NZD86_12245	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NZD86_12255	COG0509	glycine decarboxylation via glycine cleavage system
NZD86_12260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NZD86_12290	COG0142	geranyltranstransferase activity
NZD86_12295	COG0105	UTP biosynthetic process
NZD86_12300	COG1752	Esterase of the alpha-beta hydrolase superfamily
NZD86_12305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NZD86_12320	COG0517	IMP dehydrogenase activity
NZD86_12325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NZD86_12330	COG0508	dehydrogenase complex catalyzes the overall conversion of
NZD86_12335	COG0840	transmembrane signaling receptor activity
NZD86_12340	COG0475	glutathione-regulated potassium exporter activity
NZD86_12355	COG0714	Associated with various cellular activities
NZD86_12360	COG4548	von Willebrand factor, type A
NZD86_12365	COG1705	Flagellar rod assembly protein muramidase FlgJ
NZD86_12365	COG1388	LysM domain
NZD86_12385	COG0564	pseudouridine synthase activity
NZD86_12400	COG1363	Peptidase, m42
NZD86_12405	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NZD86_12410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NZD86_12420	COG4401	Chorismate mutase type I
NZD86_12425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NZD86_12430	COG0134	indole-3-glycerol-phosphate synthase activity
NZD86_12435	COG0135	phosphoribosylanthranilate isomerase activity
NZD86_12440	COG0133	tryptophan synthase activity
NZD86_12445	COG0159	tryptophan synthase activity
NZD86_12450	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NZD86_12455	COG0287	Prephenate dehydrogenase
NZD86_12460	COG1061	Type III restriction enzyme res subunit
NZD86_12470	COG5582	Belongs to the UPF0302 family
NZD86_12475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NZD86_12480	COG3949	Membrane
NZD86_12485	COG1968	undecaprenyl-diphosphatase activity
NZD86_12490	COG3314	Sporulation integral membrane protein YlbJ
NZD86_12495	COG1694	Mazg nucleotide pyrophosphohydrolase
NZD86_12505	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NZD86_12510	COG0438	transferase activity, transferring glycosyl groups
NZD86_12525	COG1199	ATP-dependent helicase activity
NZD86_12525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NZD86_12535	COG1793	dna ligase
NZD86_12545	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NZD86_12555	COG0402	S-adenosylhomocysteine deaminase activity
NZD86_12565	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NZD86_12585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NZD86_12590	COG0017	Asparaginyl-tRNA synthetase
NZD86_12595	COG3935	DnaD domain protein
NZD86_12605	COG1181	Belongs to the D-alanine--D-alanine ligase family
NZD86_12610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NZD86_12620	COG4946	Tricorn protease homolog
NZD86_12620	COG0823	Involved in the tonB-independent uptake of proteins
NZD86_12620	COG1506	peptidase
NZD86_12635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NZD86_12645	COG1053	succinate dehydrogenase
NZD86_12655	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
NZD86_12685	COG3396	Phenylacetate-CoA oxygenase
NZD86_12700	COG2151	metal-sulfur cluster biosynthetic enzyme
NZD86_12705	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NZD86_12715	COG1024	Enoyl-CoA hydratase
NZD86_12750	COG4948	Mandelate Racemase Muconate Lactonizing
NZD86_12755	COG1012	belongs to the aldehyde dehydrogenase family
NZD86_12765	COG0477	Major facilitator Superfamily
NZD86_12785	COG0395	ABC-type sugar transport system, permease component
NZD86_12790	COG4948	Mandelate Racemase Muconate Lactonizing
NZD86_12800	COG0205	6-phosphofructokinase activity
NZD86_12805	COG1063	alcohol dehydrogenase
NZD86_12810	COG4974	Belongs to the 'phage' integrase family
NZD86_12840	COG0697	spore germination
NZD86_12855	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NZD86_12865	COG1960	acyl-CoA dehydrogenase activity
NZD86_12870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NZD86_12910	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_12920	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NZD86_12925	COG0477	Major facilitator Superfamily
NZD86_12930	COG2186	Transcriptional regulator
NZD86_12940	COG0762	integral membrane protein
NZD86_12945	COG2124	cytochrome p450
NZD86_12950	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NZD86_12960	COG2318	DinB family
NZD86_12965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NZD86_12970	COG1414	Transcriptional regulator
NZD86_12975	COG0277	FAD linked oxidase domain protein
NZD86_12980	COG0247	lactate metabolic process
NZD86_12985	COG0277	FAD linked oxidase domain protein
NZD86_12990	COG1620	l-lactate permease
NZD86_12995	COG3239	Fatty acid desaturase
NZD86_13005	COG0346	lactoylglutathione lyase activity
NZD86_13020	COG2094	Belongs to the DNA glycosylase MPG family
NZD86_13030	COG0791	NLP P60 protein
NZD86_13045	COG2814	Major facilitator Superfamily
NZD86_13055	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NZD86_13060	COG1691	(AIR) carboxylase
NZD86_13065	COG1606	tRNA processing
NZD86_13075	COG2721	sulfolactate sulfo-lyase activity
NZD86_13080	COG2721	sulfolactate sulfo-lyase activity
NZD86_13095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NZD86_13100	COG0747	negative chemotaxis
NZD86_13105	COG0586	Pfam SNARE associated Golgi protein
NZD86_13110	COG2205	protein histidine kinase activity
NZD86_13115	COG0745	RESPONSE REGULATOR receiver
NZD86_13120	COG4956	integral membrane protein (PIN domain superfamily)
NZD86_13125	COG1077	Cell shape determining protein MreB Mrl
NZD86_13150	COG2115	Belongs to the xylose isomerase family
NZD86_13155	COG0673	inositol 2-dehydrogenase activity
NZD86_13165	COG1472	Belongs to the glycosyl hydrolase 3 family
NZD86_13170	COG0395	ABC-type sugar transport system, permease component
NZD86_13190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NZD86_13230	COG0004	ammonium transporteR
NZD86_13235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NZD86_13240	COG0287	Prephenate dehydrogenase
NZD86_13240	COG1605	Chorismate mutase
NZD86_13245	COG1346	cytolysis
NZD86_13255	COG3361	conserved protein (COG2071)
NZD86_13265	COG1077	Cell shape determining protein MreB Mrl
NZD86_13270	COG0456	acetyltransferase
NZD86_13325	COG1063	alcohol dehydrogenase
NZD86_13335	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NZD86_13350	COG5001	Diguanylate cyclase
NZD86_13350	COG3300	MHYT domain
NZD86_13355	COG1024	Enoyl-CoA hydratase
NZD86_13360	COG0640	Transcriptional regulator
NZD86_13365	COG2814	Major facilitator Superfamily
NZD86_13370	COG0069	glutamate synthase activity
NZD86_13385	COG1410	methionine synthase
NZD86_13385	COG0646	methionine synthase
NZD86_13390	COG2814	Major facilitator Superfamily
NZD86_13400	COG0423	glycine-tRNA ligase activity
NZD86_13405	COG0561	phosphatase activity
NZD86_13410	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NZD86_13415	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_13420	COG0754	glutathionylspermidine amidase activity
NZD86_13430	COG0174	glutamine synthetase
NZD86_13435	COG0789	Transcriptional regulator
NZD86_13440	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NZD86_13445	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NZD86_13460	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NZD86_13465	COG0464	growth
NZD86_13495	COG0697	spore germination
NZD86_13540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NZD86_13545	COG2521	methyltransferase
NZD86_13545	COG2136	Putative SAM-dependent methyltransferase
NZD86_13550	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NZD86_13555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NZD86_13565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NZD86_13575	COG2323	membrane
NZD86_13595	COG0189	ligase activity
NZD86_13615	COG2359	stage V sporulation protein S
NZD86_13620	COG1692	metallophosphoesterase
NZD86_13625	COG1418	mRNA catabolic process
NZD86_13635	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NZD86_13645	COG1058	Belongs to the CinA family
NZD86_13645	COG1546	Belongs to the CinA family
NZD86_13650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NZD86_13655	COG1666	GTP binding
NZD86_13660	COG1426	Protein conserved in bacteria
NZD86_13685	COG1674	ftsk spoiiie
NZD86_13695	COG0740	serine-type endopeptidase activity
NZD86_13700	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NZD86_13710	COG0527	aspartate kinase activity
NZD86_13715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NZD86_13720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NZD86_13725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NZD86_13735	COG0612	Peptidase, M16
NZD86_13740	COG0726	polysaccharide deacetylase
NZD86_13745	COG1185	polyribonucleotide nucleotidyltransferase activity
NZD86_13755	COG0196	riboflavin kinase activity
NZD86_13760	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NZD86_13765	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NZD86_13770	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NZD86_13785	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NZD86_13790	COG0195	Participates in both transcription termination and antitermination
NZD86_13795	COG0779	Required for maturation of 30S ribosomal subunits
NZD86_13800	COG1217	gtp-binding protein TYPA
NZD86_13810	COG0750	zinc metalloprotease
NZD86_13815	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NZD86_13820	COG4589	Belongs to the CDS family
NZD86_13825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NZD86_13830	COG0233	cytoplasmic translational termination
NZD86_13835	COG0528	UMP kinase activity
NZD86_13840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NZD86_13845	COG0052	Belongs to the universal ribosomal protein uS2 family
NZD86_13855	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NZD86_13870	COG2198	Histidine kinase
NZD86_13870	COG0643	Histidine kinase
NZD86_13875	COG2201	protein-glutamate methylesterase activity
NZD86_13885	COG1419	protein localization to endoplasmic reticulum
NZD86_13890	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NZD86_13895	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NZD86_13900	COG1684	flagellar biosynthetic protein fliR
NZD86_13905	COG1987	bacterial-type flagellum assembly
NZD86_13910	COG1338	Plays a role in the flagellum-specific transport system
NZD86_13920	COG2201	protein-glutamate methylesterase activity
NZD86_13925	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NZD86_13925	COG1776	CheC inhibitor of MCP methylation
NZD86_13930	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NZD86_13945	COG4786	Flagellar basal body rod
NZD86_13955	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NZD86_13975	COG1157	protein secretion by the type III secretion system
NZD86_13985	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NZD86_13990	COG1766	The M ring may be actively involved in energy transduction
NZD86_13995	COG1677	Flagellar hook-basal body complex protein FliE
NZD86_14015	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NZD86_14020	COG4974	Belongs to the 'phage' integrase family
NZD86_14030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NZD86_14035	COG4286	Uncharacterised protein family (UPF0160)
NZD86_14060	COG0758	DNA mediated transformation
NZD86_14060	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NZD86_14065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NZD86_14070	COG0045	succinate-CoA ligase (ADP-forming) activity
NZD86_14080	COG0606	chelatase, subunit chli
NZD86_14090	COG5002	protein histidine kinase activity
NZD86_14105	COG0586	Pfam SNARE associated Golgi protein
NZD86_14120	COG0463	Glycosyl transferase, family 2
NZD86_14145	COG0792	nuclease activity
NZD86_14150	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NZD86_14170	COG0335	large ribosomal subunit rRNA binding
NZD86_14195	COG1607	acyl-coa hydrolase
NZD86_14200	COG0739	heme binding
NZD86_14210	COG0564	pseudouridine synthase activity
NZD86_14250	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NZD86_14255	COG0542	response to heat
NZD86_14260	COG1595	DNA-templated transcription, initiation
NZD86_14275	COG1131	(ABC) transporter
NZD86_14280	COG1725	Transcriptional regulator
NZD86_14285	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_14305	COG0336	Belongs to the RNA methyltransferase TrmD family
NZD86_14320	COG1837	Belongs to the UPF0109 family
NZD86_14330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NZD86_14335	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NZD86_14340	COG0552	protein localization to endoplasmic reticulum
NZD86_14345	COG1196	nuclear chromosome segregation
NZD86_14350	COG0571	ribonuclease III activity
NZD86_14355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NZD86_14360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NZD86_14365	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_14370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NZD86_14375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NZD86_14380	COG0416	fatty acid biosynthetic process
NZD86_14385	COG1349	DNA-binding transcription factor activity
NZD86_14390	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NZD86_14400	COG1752	Esterase of the alpha-beta hydrolase superfamily
NZD86_14405	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NZD86_14410	COG0742	ribosomal rna small subunit methyltransferase
NZD86_14420	COG0154	amidase activity
NZD86_14435	COG0688	phosphatidylethanolamine metabolic process
NZD86_14445	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NZD86_14450	COG1302	Protein conserved in bacteria
NZD86_14455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NZD86_14465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NZD86_14470	COG1162	GTPase activity
NZD86_14475	COG2815	serine threonine protein kinase
NZD86_14475	COG0515	serine threonine protein kinase
NZD86_14480	COG0631	protein serine/threonine phosphatase activity
NZD86_14485	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NZD86_14490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NZD86_14490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NZD86_14495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NZD86_14500	COG0242	peptide deformylase activity
NZD86_14505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NZD86_14510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NZD86_14515	COG1758	RNA polymerase activity
NZD86_14520	COG0194	GDP metabolic process
NZD86_14525	COG1561	YicC-like family, N-terminal region
NZD86_14530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NZD86_14545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NZD86_14555	COG0284	orotidine-5'-phosphate decarboxylase activity
NZD86_14565	COG0505	Belongs to the CarA family
NZD86_14570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NZD86_14580	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NZD86_14585	COG0564	pseudouridine synthase activity
NZD86_14590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NZD86_14595	COG1809	phosphosulfolactate synthase activity
NZD86_14605	COG3599	regulation of cell shape
NZD86_14620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NZD86_14630	COG1873	PFAM PRC-barrel domain
NZD86_14635	COG1191	sigma factor activity
NZD86_14640	COG1191	sigma factor activity
NZD86_14650	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NZD86_14655	COG0849	cell division
NZD86_14660	COG3856	small basic protein
NZD86_14675	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NZD86_14680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NZD86_14685	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NZD86_14690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NZD86_14695	COG0772	Belongs to the SEDS family
NZD86_14700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NZD86_14705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NZD86_14710	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NZD86_14715	COG0768	penicillin binding
NZD86_14720	COG0768	penicillin binding
NZD86_14730	COG0275	rRNA processing
NZD86_14735	COG2001	Belongs to the MraZ family
NZD86_14740	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NZD86_14745	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_14770	COG0301	tRNA thio-modification
NZD86_14775	COG1104	cysteine desulfurase activity
NZD86_14780	COG0740	serine-type endopeptidase activity
NZD86_14805	COG3906	Belongs to the UPF0473 family
NZD86_14810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NZD86_14835	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NZD86_14840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NZD86_14855	COG0137	argininosuccinate synthase activity
NZD86_14860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NZD86_14865	COG0067	glutamate synthase
NZD86_14865	COG0069	glutamate synthase activity
NZD86_14865	COG0070	glutamate synthase
NZD86_14870	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NZD86_14875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NZD86_14880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NZD86_14885	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NZD86_14895	COG1832	CoA-binding protein
NZD86_14905	COG0673	inositol 2-dehydrogenase activity
NZD86_14920	COG0673	inositol 2-dehydrogenase activity
NZD86_14930	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NZD86_14940	COG1737	Transcriptional regulator
NZD86_14955	COG0444	Belongs to the ABC transporter superfamily
NZD86_14960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NZD86_14965	COG0601	transmembrane transport
NZD86_14970	COG4166	transmembrane transport
NZD86_14985	COG4948	Mandelate Racemase Muconate Lactonizing
NZD86_15005	COG0512	Glutamine amidotransferase of anthranilate synthase
NZD86_15060	COG1063	alcohol dehydrogenase
NZD86_15070	COG1278	Cold shock
NZD86_15095	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_15110	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_15115	COG2814	Major facilitator Superfamily
NZD86_15120	COG0438	transferase activity, transferring glycosyl groups
NZD86_15125	COG0235	Class ii aldolase
NZD86_15135	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
NZD86_15140	COG1063	alcohol dehydrogenase
NZD86_15205	COG0697	spore germination
NZD86_15220	COG3344	reverse transcriptase
NZD86_15260	COG2188	Transcriptional regulator
NZD86_15265	COG0366	Alpha amylase catalytic
NZD86_15270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NZD86_15270	COG1263	PTS System
NZD86_15280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NZD86_15285	COG0561	phosphatase activity
NZD86_15295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NZD86_15305	COG0179	Fumarylacetoacetate (FAA) hydrolase
NZD86_15315	COG1414	Transcriptional regulator
NZD86_15320	COG0840	transmembrane signaling receptor activity
NZD86_15330	COG0235	Class ii aldolase
NZD86_15335	COG4638	Rieske (2fe-2S)
NZD86_15345	COG0583	DNA-binding transcription factor activity
NZD86_15350	COG2814	Major facilitator Superfamily
NZD86_15355	COG0235	Class ii aldolase
NZD86_15365	COG1335	isochorismatase
NZD86_15380	COG0814	amino acid
NZD86_15385	COG0697	spore germination
NZD86_15390	COG3383	formate dehydrogenase (NAD+) activity
NZD86_15400	COG1426	Protein conserved in bacteria
NZD86_15415	COG0163	prenyltransferase activity
NZD86_15420	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NZD86_15425	COG0583	DNA-binding transcription factor activity
NZD86_15445	COG0028	Belongs to the TPP enzyme family
NZD86_15450	COG5577	PFAM Coat F domain
NZD86_15465	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_15475	COG3436	PFAM IS66 Orf2 family protein
NZD86_15495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NZD86_15510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NZD86_15525	COG0583	DNA-binding transcription factor activity
NZD86_15545	COG3384	dioxygenase
NZD86_15550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NZD86_15560	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NZD86_15590	COG3384	dioxygenase
NZD86_15595	COG0251	oxidation-reduction process
NZD86_15610	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NZD86_15615	COG4638	Rieske (2fe-2S)
NZD86_15620	COG2814	Major facilitator Superfamily
NZD86_15630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NZD86_15640	COG3384	dioxygenase
NZD86_15645	COG0251	oxidation-reduction process
NZD86_15655	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_15660	COG1063	alcohol dehydrogenase
NZD86_15685	COG1063	alcohol dehydrogenase
NZD86_15715	COG1012	belongs to the aldehyde dehydrogenase family
NZD86_15720	COG0028	Belongs to the TPP enzyme family
NZD86_15730	COG0583	DNA-binding transcription factor activity
NZD86_15755	COG0747	negative chemotaxis
NZD86_15760	COG0747	negative chemotaxis
NZD86_15765	COG0601	transmembrane transport
NZD86_15770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NZD86_15775	COG4608	Belongs to the ABC transporter superfamily
NZD86_15780	COG0444	Belongs to the ABC transporter superfamily
NZD86_15795	COG0494	nUDIX hydrolase
NZD86_15800	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NZD86_15805	COG1363	Peptidase, m42
NZD86_15810	COG3377	Domain of unknown function (DUF1805)
NZD86_15820	COG0586	Pfam SNARE associated Golgi protein
NZD86_15825	COG1078	dGTPase activity
NZD86_15830	COG0316	Belongs to the HesB IscA family
NZD86_15835	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NZD86_15840	COG1982	Orn Lys Arg decarboxylase major
NZD86_15860	COG0436	Aminotransferase
NZD86_15865	COG0772	Belongs to the SEDS family
NZD86_15870	COG0584	glycerophosphoryl diester phosphodiesterase
NZD86_15880	COG0772	Belongs to the SEDS family
NZD86_15890	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NZD86_15900	COG1956	GAF domain-containing protein
NZD86_15925	COG2050	protein possibly involved in aromatic compounds catabolism
NZD86_15935	COG0083	homoserine kinase activity
NZD86_15940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NZD86_15945	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NZD86_15955	COG0612	Peptidase, M16
NZD86_15960	COG0612	Peptidase, M16
NZD86_15975	COG0477	Major facilitator Superfamily
NZD86_15980	COG0768	penicillin binding
NZD86_15985	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NZD86_15990	COG1131	(ABC) transporter
NZD86_15995	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NZD86_16000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NZD86_16015	COG0371	Dehydrogenase
NZD86_16050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NZD86_16060	COG2376	Dihydroxyacetone kinase
NZD86_16065	COG2186	Transcriptional regulator
NZD86_16070	COG2271	Major facilitator Superfamily
NZD86_16075	COG1960	acyl-CoA dehydrogenase activity
NZD86_16080	COG0183	Belongs to the thiolase family
NZD86_16085	COG1024	Enoyl-CoA hydratase
NZD86_16085	COG1250	3-hydroxyacyl-CoA dehydrogenase
NZD86_16090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NZD86_16095	COG0537	adenosine 5'-monophosphoramidase activity
NZD86_16120	COG0587	DNA-directed DNA polymerase activity
NZD86_16140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NZD86_16145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NZD86_16150	COG1121	(ABC) transporter
NZD86_16160	COG0735	belongs to the Fur family
NZD86_16170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NZD86_16205	COG0438	transferase activity, transferring glycosyl groups
NZD86_16210	COG0531	amino acid
NZD86_16225	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NZD86_16230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NZD86_16240	COG0823	Involved in the tonB-independent uptake of proteins
NZD86_16240	COG1506	peptidase
NZD86_16240	COG4946	Tricorn protease homolog
NZD86_16245	COG0114	fumarate hydratase activity
NZD86_16260	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NZD86_16265	COG2086	electron transfer activity
NZD86_16270	COG1309	transcriptional regulator
NZD86_16280	COG0450	alkyl hydroperoxide reductase
NZD86_16300	COG0719	Fe-S assembly protein
NZD86_16305	COG0822	iron-sulfur transferase activity
NZD86_16310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NZD86_16315	COG0719	Fe-S assembly protein
NZD86_16320	COG0396	ATPase activity
NZD86_16325	COG2151	metal-sulfur cluster biosynthetic enzyme
NZD86_16330	COG0686	Belongs to the AlaDH PNT family
NZD86_16345	COG1595	DNA-templated transcription, initiation
NZD86_16350	COG0167	dihydroorotate dehydrogenase activity
NZD86_16360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NZD86_16375	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NZD86_16380	COG0302	gtp cyclohydrolase
NZD86_16415	COG0586	Pfam SNARE associated Golgi protein
NZD86_16430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NZD86_16435	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NZD86_16440	COG1160	GTP binding
NZD86_16445	COG1363	Peptidase, m42
NZD86_16460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NZD86_16465	COG1295	ribonuclease BN
NZD86_16470	COG0564	pseudouridine synthase activity
NZD86_16475	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NZD86_16495	COG1022	Amp-dependent synthetase and ligase
NZD86_16505	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NZD86_16515	COG1213	nucleotidyl transferase
NZD86_16525	COG0438	transferase activity, transferring glycosyl groups
NZD86_16535	COG2391	methyltransferase activity
NZD86_16540	COG1960	acyl-CoA dehydrogenase activity
NZD86_16545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NZD86_16555	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NZD86_16570	COG4221	oxidoreductase activity
NZD86_16590	COG0482	sulfurtransferase activity
NZD86_16595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NZD86_16600	COG4684	Psort location CytoplasmicMembrane, score
NZD86_16605	COG0697	spore germination
NZD86_16610	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NZD86_16620	COG0583	DNA-binding transcription factor activity
NZD86_16630	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NZD86_16635	COG1683	Conserved Protein
NZD86_16655	COG0456	acetyltransferase
NZD86_16655	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NZD86_16670	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_16685	COG0463	Glycosyl transferase, family 2
NZD86_16685	COG0457	Tetratricopeptide repeat
NZD86_16690	COG0412	Dienelactone hydrolase
NZD86_16695	COG0671	phosphoesterase, PA-phosphatase related
NZD86_16700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NZD86_16710	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NZD86_16720	COG1122	ATPase activity
NZD86_16725	COG4721	ABC-type cobalt transport system, permease component
NZD86_16730	COG1494	fructose-1,6-bisphosphatase
NZD86_16740	COG0697	spore germination
NZD86_16765	COG1595	DNA-templated transcription, initiation
NZD86_16775	COG0140	phosphoribosyl-ATP diphosphatase activity
NZD86_16775	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NZD86_16785	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NZD86_16790	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NZD86_16795	COG0131	Imidazoleglycerol-phosphate dehydratase
NZD86_16800	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NZD86_16805	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NZD86_16810	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NZD86_16820	COG2423	ornithine cyclodeaminase activity
NZD86_16825	COG2271	Major facilitator Superfamily
NZD86_16840	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NZD86_16850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NZD86_16860	COG0109	protoheme IX farnesyltransferase activity
NZD86_16865	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NZD86_16870	COG0116	Belongs to the methyltransferase superfamily
NZD86_16875	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NZD86_16880	COG1979	alcohol dehydrogenase
NZD86_16890	COG2081	HI0933 family
NZD86_16905	COG0424	maF-like protein
NZD86_16910	COG0626	cystathionine gamma-synthase activity
NZD86_16920	COG2363	Small membrane protein
NZD86_16925	COG0154	amidase activity
NZD86_16930	COG0655	NAD(P)H dehydrogenase (quinone) activity
NZD86_16955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NZD86_16970	COG5002	protein histidine kinase activity
NZD86_16980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NZD86_16985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NZD86_16995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NZD86_17000	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NZD86_17005	COG1085	galactose-1-phosphate uridylyltransferase
NZD86_17010	COG1349	DNA-binding transcription factor activity
NZD86_17050	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_17090	COG0210	DNA helicase
NZD86_17110	COG0210	DNA helicase
NZD86_17115	COG0210	DNA helicase
NZD86_17125	COG2176	DNA-directed DNA polymerase activity
NZD86_17180	COG0438	transferase activity, transferring glycosyl groups
NZD86_17185	COG1597	lipid kinase activity
NZD86_17190	COG0204	Acyl-transferase
NZD86_17260	COG2814	Major facilitator Superfamily
NZD86_17270	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NZD86_17295	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NZD86_17305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NZD86_17310	COG1012	belongs to the aldehyde dehydrogenase family
NZD86_17325	COG0252	asparaginase activity
NZD86_17330	COG2814	Major facilitator Superfamily
NZD86_17335	COG2814	Major facilitator Superfamily
NZD86_17340	COG0477	Major facilitator Superfamily
NZD86_17345	COG4294	response to UV
NZD86_17350	COG3973	AAA domain
NZD86_17355	COG0598	Magnesium transport protein CorA
NZD86_17365	COG0318	PFAM AMP-dependent synthetase and ligase
NZD86_17375	COG3844	kynureninase activity
NZD86_17380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NZD86_17390	COG1335	isochorismatase
NZD86_17395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NZD86_17405	COG1012	belongs to the aldehyde dehydrogenase family
NZD86_17420	COG2318	DinB family
NZD86_17440	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NZD86_17450	COG4821	SIS domain
NZD86_17460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NZD86_17465	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NZD86_17470	COG3716	PTS system mannose fructose sorbose family IID component
NZD86_17480	COG2188	Transcriptional regulator
NZD86_17490	COG1609	Transcriptional regulator
NZD86_17495	COG1312	Catalyzes the dehydration of D-mannonate
NZD86_17500	COG0800	Aldolase
NZD86_17505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NZD86_17510	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_17520	COG0667	Aldo Keto reductase
NZD86_17535	COG1408	metallophosphoesterase
NZD86_17580	COG2353	YceI-like domain
NZD86_17585	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_17590	COG2378	regulation of single-species biofilm formation
NZD86_17615	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NZD86_17620	COG1486	melibiose metabolic process
NZD86_17635	COG1175	transmembrane transport
NZD86_17640	COG1840	ABC-type Fe3 transport system, periplasmic component
NZD86_17650	COG0531	amino acid
NZD86_17655	COG1940	carbohydrate kinase activity
NZD86_17670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NZD86_17675	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NZD86_17685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NZD86_17685	COG1263	PTS System
NZD86_17690	COG1263	PTS System
NZD86_17690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NZD86_17695	COG3711	transcriptional antiterminator
NZD86_17715	COG1131	(ABC) transporter
NZD86_17725	COG1309	transcriptional regulator
NZD86_17745	COG3011	Protein conserved in bacteria
NZD86_17755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NZD86_17785	COG0393	Putative heavy-metal-binding
NZD86_17800	COG3153	acetyltransferase
NZD86_17800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NZD86_17805	COG1741	Belongs to the pirin family
NZD86_17810	COG3340	Belongs to the peptidase S51 family
NZD86_17815	COG2183	response to ionizing radiation
NZD86_17825	COG0483	inositol monophosphate 1-phosphatase activity
NZD86_17830	COG2046	Belongs to the sulfate adenylyltransferase family
NZD86_17840	COG0753	catalase activity
NZD86_17850	COG1733	regulation of RNA biosynthetic process
NZD86_17860	COG3173	Aminoglycoside phosphotransferase
NZD86_17875	COG1671	Belongs to the UPF0178 family
NZD86_17880	COG1119	ATPase activity
NZD86_17885	COG0667	Aldo Keto reductase
NZD86_17890	COG1902	pentaerythritol trinitrate reductase activity
NZD86_17905	COG1595	DNA-templated transcription, initiation
NZD86_17935	COG4895	conserved protein (DUF2196)
NZD86_17940	COG0488	(ABC) transporter
NZD86_17945	COG0513	Belongs to the DEAD box helicase family
NZD86_17950	COG0531	amino acid
NZD86_17955	COG0488	(ABC) transporter
NZD86_17975	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_17980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NZD86_17990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NZD86_17995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NZD86_18000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NZD86_18020	COG1349	DNA-binding transcription factor activity
NZD86_18030	COG0519	Catalyzes the synthesis of GMP from XMP
NZD86_18055	COG1024	Enoyl-CoA hydratase
NZD86_18060	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_18065	COG1960	acyl-CoA dehydrogenase activity
NZD86_18085	COG0776	regulation of translation
NZD86_18090	COG0438	transferase activity, transferring glycosyl groups
NZD86_18100	COG0697	spore germination
NZD86_18130	COG0406	alpha-ribazole phosphatase activity
NZD86_18135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NZD86_18140	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NZD86_18150	COG0352	thiamine-phosphate diphosphorylase activity
NZD86_18155	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NZD86_18160	COG0351	phosphomethylpyrimidine kinase
NZD86_18165	COG4721	ABC-type cobalt transport system, permease component
NZD86_18175	COG5634	Uncharacterized conserved protein (DUF2278)
NZD86_18195	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NZD86_18200	COG1744	ABC transporter substrate-binding protein PnrA-like
NZD86_18205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NZD86_18210	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NZD86_18215	COG3457	Alanine racemase
NZD86_18220	COG0626	cystathionine gamma-synthase activity
NZD86_18225	COG1735	metal-dependent hydrolase with the TIM-barrel fold
NZD86_18245	COG2188	Transcriptional regulator
NZD86_18250	COG0561	phosphatase activity
NZD86_18255	COG1349	DNA-binding transcription factor activity
NZD86_18260	COG0363	glucosamine-6-phosphate deaminase activity
NZD86_18270	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_18285	COG0559	Belongs to the binding-protein-dependent transport system permease family
NZD86_18320	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NZD86_18325	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NZD86_18330	COG0183	Belongs to the thiolase family
NZD86_18335	COG0583	DNA-binding transcription factor activity
NZD86_18360	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_18380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NZD86_18415	COG1172	Belongs to the binding-protein-dependent transport system permease family
NZD86_18430	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_18435	COG1250	3-hydroxyacyl-CoA dehydrogenase
NZD86_18440	COG3290	protein histidine kinase activity
NZD86_18440	COG3829	transcription factor binding
NZD86_18445	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NZD86_18450	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_18455	COG0183	Belongs to the thiolase family
NZD86_18475	COG1960	acyl-CoA dehydrogenase activity
NZD86_18480	COG0318	PFAM AMP-dependent synthetase and ligase
NZD86_18485	COG1024	Enoyl-CoA hydratase
NZD86_18490	COG0427	acetyl-CoA hydrolase
NZD86_18495	COG1024	Enoyl-CoA hydratase
NZD86_18500	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_18510	COG1960	acyl-CoA dehydrogenase activity
NZD86_18515	COG1042	CoA-binding domain protein
NZD86_18515	COG0045	succinate-CoA ligase (ADP-forming) activity
NZD86_18515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NZD86_18535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NZD86_18550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NZD86_18560	COG5002	protein histidine kinase activity
NZD86_18565	COG0656	L-ascorbic acid biosynthetic process
NZD86_18570	COG2197	response regulator
NZD86_18580	COG3850	Histidine kinase
NZD86_18590	COG4221	oxidoreductase activity
NZD86_18615	COG0492	ferredoxin-NADP+ reductase activity
NZD86_18620	COG1741	Belongs to the pirin family
NZD86_18625	COG0747	negative chemotaxis
NZD86_18645	COG0492	ferredoxin-NADP+ reductase activity
NZD86_18655	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NZD86_18665	COG1309	transcriptional regulator
NZD86_18670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NZD86_18700	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_18715	COG1846	Transcriptional regulator
NZD86_18725	COG3961	Belongs to the TPP enzyme family
NZD86_18730	COG1609	Transcriptional regulator
NZD86_18735	COG3395	kinase activity
NZD86_18740	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NZD86_18755	COG0385	Bile acid
NZD86_18775	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_18800	COG2318	DinB family
NZD86_18805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NZD86_18815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NZD86_18820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NZD86_18840	COG5337	Spore coat protein CotH
NZD86_18870	COG2427	Protein of unknown function (DUF1641)
NZD86_18875	COG3383	formate dehydrogenase (NAD+) activity
NZD86_18885	COG1733	regulation of RNA biosynthetic process
NZD86_18890	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NZD86_18895	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NZD86_18900	COG1309	transcriptional regulator
NZD86_18905	COG2267	carboxylic ester hydrolase activity
NZD86_18910	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NZD86_18920	COG0604	alcohol dehydrogenase
NZD86_18935	COG2508	Transcriptional regulator
NZD86_18940	COG0318	PFAM AMP-dependent synthetase and ligase
NZD86_18945	COG0183	Belongs to the thiolase family
NZD86_18950	COG1024	Enoyl-CoA hydratase
NZD86_18955	COG1250	3-hydroxyacyl-CoA dehydrogenase
NZD86_18965	COG5002	protein histidine kinase activity
NZD86_18975	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NZD86_18980	COG2720	vancomycin resistance protein
NZD86_18995	COG1174	glycine betaine transport
NZD86_19000	COG0517	IMP dehydrogenase activity
NZD86_19000	COG1125	glycine betaine transport
NZD86_19005	COG0583	DNA-binding transcription factor activity
NZD86_19010	COG0531	amino acid
NZD86_19025	COG0318	PFAM AMP-dependent synthetase and ligase
NZD86_19030	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_19035	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NZD86_19040	COG1960	acyl-CoA dehydrogenase activity
NZD86_19045	COG1760	l-serine dehydratase
NZD86_19050	COG1760	l-serine dehydratase
NZD86_19055	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NZD86_19065	COG1181	Belongs to the D-alanine--D-alanine ligase family
NZD86_19105	COG3842	ATPase activity
NZD86_19110	COG0395	ABC-type sugar transport system, permease component
NZD86_19115	COG2188	Transcriptional regulator
NZD86_19130	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_19160	COG1509	lysine 2,3-aminomutase activity
NZD86_19175	COG0840	transmembrane signaling receptor activity
NZD86_19180	COG0477	Major facilitator Superfamily
NZD86_19180	COG2814	Major facilitator Superfamily
NZD86_19185	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NZD86_19190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NZD86_19200	COG1802	Transcriptional regulator
NZD86_19210	COG2814	Major facilitator Superfamily
NZD86_19225	COG0179	Fumarylacetoacetate (FAA) hydrolase
NZD86_19240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NZD86_19245	COG1414	Transcriptional regulator
NZD86_19255	COG0708	Exodeoxyribonuclease III
NZD86_19260	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NZD86_19265	COG1518	maintenance of DNA repeat elements
NZD86_19265	COG1468	defense response to virus
NZD86_19270	COG1468	defense response to virus
NZD86_19270	COG1518	maintenance of DNA repeat elements
NZD86_19315	COG2271	Major facilitator Superfamily
NZD86_19320	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NZD86_19325	COG3395	kinase activity
NZD86_19330	COG1349	DNA-binding transcription factor activity
NZD86_19335	COG1349	DNA-binding transcription factor activity
NZD86_19345	COG1070	Carbohydrate kinase
NZD86_19350	COG2188	Transcriptional regulator
NZD86_19370	COG1879	ABC-type sugar transport system periplasmic component
NZD86_19375	COG1129	ABC transporter
NZD86_19380	COG1172	Belongs to the binding-protein-dependent transport system permease family
NZD86_19425	COG1695	Transcriptional regulator
NZD86_19450	COG0656	L-ascorbic acid biosynthetic process
NZD86_19455	COG2814	Major facilitator Superfamily
NZD86_19460	COG2207	Transcriptional regulator
NZD86_19475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NZD86_19480	COG0557	exoribonuclease II activity
NZD86_19485	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NZD86_19490	COG0148	phosphopyruvate hydratase activity
NZD86_19500	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NZD86_19505	COG0149	triose-phosphate isomerase activity
NZD86_19510	COG0126	phosphoglycerate kinase activity
NZD86_19520	COG5002	protein histidine kinase activity
NZD86_19535	COG1164	Oligoendopeptidase f
NZD86_19540	COG0295	cytidine deaminase activity
NZD86_19565	COG0019	diaminopimelate decarboxylase activity
NZD86_19570	COG5577	PFAM Coat F domain
NZD86_19580	COG2155	Conserved Protein
NZD86_19600	COG0473	3-isopropylmalate dehydrogenase activity
NZD86_19610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NZD86_19620	COG0531	amino acid
NZD86_19640	COG2201	protein-glutamate methylesterase activity
NZD86_19665	COG4974	Belongs to the 'phage' integrase family
NZD86_19710	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NZD86_19730	COG0702	epimerase
NZD86_19735	COG4585	Histidine kinase
NZD86_19740	COG2197	response regulator
NZD86_19745	COG2217	Heavy metal translocating P-type atpase
NZD86_19760	COG4549	nuclear export factor GLE1
NZD86_19765	COG0745	RESPONSE REGULATOR receiver
NZD86_19770	COG2205	protein histidine kinase activity
NZD86_19775	COG2205	protein histidine kinase activity
NZD86_19780	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NZD86_19790	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NZD86_19820	COG1937	Protein conserved in bacteria
NZD86_19835	COG0425	Belongs to the sulfur carrier protein TusA family
NZD86_19840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NZD86_19840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NZD86_19845	COG0425	Belongs to the sulfur carrier protein TusA family
NZD86_19845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NZD86_19850	COG0730	response to heat
NZD86_19855	COG2210	Belongs to the sulfur carrier protein TusA family
NZD86_19870	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NZD86_19875	COG0154	amidase activity
NZD86_19885	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NZD86_19910	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NZD86_19915	COG0210	DNA helicase
NZD86_19955	COG0523	cobalamin synthesis protein
NZD86_19960	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_19970	COG0252	asparaginase activity
NZD86_19980	COG3829	transcription factor binding
NZD86_20000	COG4499	WXG100 protein secretion system (Wss), protein YukC
NZD86_20000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NZD86_20005	COG1278	Cold shock
NZD86_20040	COG2201	protein-glutamate methylesterase activity
NZD86_20045	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NZD86_20050	COG0784	Response regulator, receiver
NZD86_20050	COG0643	Histidine kinase
NZD86_20050	COG2198	Histidine kinase
NZD86_20055	COG2198	Histidine kinase
NZD86_20055	COG0643	Histidine kinase
NZD86_20090	COG3344	reverse transcriptase
NZD86_20125	COG0697	spore germination
NZD86_20155	COG2199	diguanylate cyclase activity
NZD86_20165	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_20185	COG0667	Aldo Keto reductase
NZD86_20200	COG4122	O-methyltransferase activity
NZD86_20205	COG0569	domain protein
NZD86_20220	COG1132	(ABC) transporter
NZD86_20225	COG1132	(ABC) transporter
NZD86_20230	COG1686	Belongs to the peptidase S11 family
NZD86_20250	COG1612	heme a metabolic process
NZD86_20255	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NZD86_20260	COG1845	cytochrome c oxidase, subunit III
NZD86_20270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NZD86_20290	COG2197	response regulator
NZD86_20295	COG4585	Histidine kinase
NZD86_20305	COG1131	(ABC) transporter
NZD86_20310	COG0531	amino acid
NZD86_20315	COG0824	Thioesterase
NZD86_20320	COG2271	Major facilitator Superfamily
NZD86_20325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NZD86_20335	COG1802	Transcriptional regulator
NZD86_20350	COG2271	Major facilitator Superfamily
NZD86_20355	COG3263	regulation of cellular component size
NZD86_20375	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_20385	COG4846	Membrane protein involved in cytochrome C biogenesis
NZD86_20390	COG1234	tRNA 3'-trailer cleavage
NZD86_20400	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_20405	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
NZD86_20410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NZD86_20415	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NZD86_20430	COG0673	inositol 2-dehydrogenase activity
NZD86_20435	COG0596	Alpha beta hydrolase
NZD86_20440	COG0791	NLP P60 protein
NZD86_20440	COG1388	LysM domain
NZD86_20455	COG1295	ribonuclease BN
NZD86_20460	COG2719	SpoVR family
NZD86_20480	COG0454	-acetyltransferase
NZD86_20480	COG0456	acetyltransferase
NZD86_20485	COG0514	ATP-dependent DNA helicase (RecQ)
NZD86_20490	COG1827	regulation of RNA biosynthetic process
NZD86_20495	COG2199	diguanylate cyclase activity
NZD86_20500	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NZD86_20510	COG2766	serine protein kinase
NZD86_20550	COG2318	DinB family
NZD86_20560	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NZD86_20570	COG1414	Transcriptional regulator
NZD86_20575	COG0538	isocitrate dehydrogenase activity
NZD86_20585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NZD86_20590	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NZD86_20595	COG0328	RNA-DNA hybrid ribonuclease activity
NZD86_20605	COG0697	spore germination
NZD86_20615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NZD86_20625	COG4493	Belongs to the UPF0637 family
NZD86_20635	COG1111	helicase
NZD86_20635	COG1205	dead DEAH box helicase
NZD86_20650	COG0628	permease
NZD86_20665	COG1609	Transcriptional regulator
NZD86_20670	COG0495	leucyl-tRNA aminoacylation
NZD86_20675	COG0670	Belongs to the BI1 family
NZD86_20680	COG1194	a g-specific adenine glycosylase
NZD86_20700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NZD86_20710	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NZD86_20715	COG1660	Displays ATPase and GTPase activities
NZD86_20720	COG1051	belongs to the nudix hydrolase family
NZD86_20730	COG0018	arginyl-trna synthetase
NZD86_20740	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NZD86_20745	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NZD86_20750	COG0556	nucleotide-excision repair
NZD86_20760	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NZD86_20770	COG2177	Part of the ABC transporter FtsEX involved in
NZD86_20775	COG2884	Cell division ATP-binding protein ftsE
NZD86_20780	COG4948	Mandelate Racemase Muconate Lactonizing
NZD86_20915	COG0835	chemotaxis
NZD86_20920	COG0346	lactoylglutathione lyase activity
NZD86_20940	COG1587	Uroporphyrinogen-III synthase
NZD86_20970	COG2814	Major facilitator Superfamily
NZD86_20990	COG1268	BioY protein
NZD86_20995	COG1122	ATPase activity
NZD86_21000	COG1122	ATPase activity
NZD86_21010	COG0175	sulfate reduction
NZD86_21015	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NZD86_21020	COG0436	Aminotransferase
NZD86_21025	COG2223	nitrite transmembrane transporter activity
NZD86_21030	COG2233	PERMEase
NZD86_21035	COG1215	transferase activity, transferring glycosyl groups
NZD86_21040	COG1968	undecaprenyl-diphosphatase activity
NZD86_21045	COG2318	DinB family
NZD86_21050	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NZD86_21055	COG2362	D-Aminopeptidase
NZD86_21060	COG4946	Tricorn protease homolog
NZD86_21060	COG0823	Involved in the tonB-independent uptake of proteins
NZD86_21060	COG1506	peptidase
NZD86_21065	COG4166	transmembrane transport
NZD86_21070	COG4608	Belongs to the ABC transporter superfamily
NZD86_21075	COG0444	Belongs to the ABC transporter superfamily
NZD86_21080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NZD86_21085	COG0601	transmembrane transport
NZD86_21115	COG0151	Belongs to the GarS family
NZD86_21120	COG0138	bifunctional purine biosynthesis protein purh
NZD86_21125	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NZD86_21130	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NZD86_21135	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NZD86_21140	COG0047	phosphoribosylformylglycinamidine synthase activity
NZD86_21145	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NZD86_21150	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NZD86_21155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NZD86_21160	COG2252	PERMEase
NZD86_21165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NZD86_21165	COG0519	Catalyzes the synthesis of GMP from XMP
NZD86_21170	COG1305	Transglutaminase-like
NZD86_21180	COG0714	Associated with various cellular activities
NZD86_21185	COG1376	ErfK ybiS ycfS ynhG family protein
NZD86_21195	COG0459	protein refolding
NZD86_21205	COG1763	Mo-molybdopterin cofactor biosynthetic process
NZD86_21210	COG1546	Belongs to the CinA family
NZD86_21210	COG1058	Belongs to the CinA family
NZD86_21220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NZD86_21225	COG0671	phosphoesterase, PA-phosphatase related
NZD86_21230	COG0488	(ABC) transporter
NZD86_21235	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NZD86_21240	COG0456	acetyltransferase
NZD86_21245	COG1214	PFAM Peptidase M22, glycoprotease
NZD86_21250	COG0802	atpase or kinase
NZD86_21255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NZD86_21275	COG2002	toxin-antitoxin pair type II binding
NZD86_21280	COG4191	Histidine kinase
NZD86_21290	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NZD86_21295	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NZD86_21300	COG2337	Toxic component of a toxin-antitoxin (TA) module
NZD86_21310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NZD86_21315	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NZD86_21320	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NZD86_21320	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NZD86_21325	COG0736	holo-[acyl-carrier-protein] synthase activity
NZD86_21335	COG0024	Methionine aminopeptidase
NZD86_21345	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NZD86_21365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NZD86_21375	COG1744	ABC transporter substrate-binding protein PnrA-like
NZD86_21380	COG3845	ABC transporter
NZD86_21385	COG4603	Belongs to the binding-protein-dependent transport system permease family
NZD86_21390	COG1079	Belongs to the binding-protein-dependent transport system permease family
NZD86_21400	COG0662	Cupin 2, conserved barrel domain protein
NZD86_21400	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NZD86_21410	COG2814	Major facilitator Superfamily
NZD86_21415	COG0789	Transcriptional regulator
NZD86_21420	COG1335	isochorismatase
NZD86_21425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NZD86_21435	COG4846	Membrane protein involved in cytochrome C biogenesis
NZD86_21440	COG1033	growth of symbiont in host cell
NZD86_21440	COG2409	Drug exporters of the RND superfamily
NZD86_21445	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_21465	COG5002	protein histidine kinase activity
NZD86_21500	COG3191	aminopeptidase activity
NZD86_21505	COG0237	dephospho-CoA kinase activity
NZD86_21510	COG2866	Carboxypeptidase
NZD86_21520	COG1131	(ABC) transporter
NZD86_21530	COG1595	DNA-templated transcription, initiation
NZD86_21570	COG0277	FAD linked oxidase domain protein
NZD86_21580	COG1012	belongs to the aldehyde dehydrogenase family
NZD86_21585	COG0129	dihydroxy-acid dehydratase activity
NZD86_21595	COG4948	Mandelate Racemase Muconate Lactonizing
NZD86_21600	COG1802	Transcriptional regulator
NZD86_21615	COG0463	Glycosyl transferase, family 2
NZD86_21615	COG0457	Tetratricopeptide repeat
NZD86_21655	COG0028	Belongs to the TPP enzyme family
NZD86_21655	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
NZD86_21670	COG1126	abc transporter atp-binding protein
NZD86_21675	COG0765	amino acid transport
NZD86_21680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NZD86_21685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NZD86_21695	COG3119	arylsulfatase activity
NZD86_21705	COG4191	Histidine kinase
NZD86_21735	COG0791	NLP P60 protein
NZD86_21740	COG1077	Cell shape determining protein MreB Mrl
NZD86_21785	COG2909	trisaccharide binding
NZD86_21800	COG0668	transmembrane transport
NZD86_21820	COG0791	NLP P60 protein
NZD86_21820	COG1388	LysM domain
NZD86_21825	COG2246	polysaccharide biosynthetic process
NZD86_21830	COG0463	Glycosyl transferase, family 2
NZD86_21835	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NZD86_21875	COG1028	Short-chain dehydrogenase reductase Sdr
NZD86_21885	COG0302	gtp cyclohydrolase
NZD86_21935	COG4193	domain, Protein
NZD86_21935	COG5263	repeat protein
NZD86_21945	COG3447	MASE1 domain protein
NZD86_21945	COG5001	Diguanylate cyclase
NZD86_21945	COG5002	protein histidine kinase activity
NZD86_21980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NZD86_21990	COG2814	Major facilitator Superfamily
NZD86_22000	COG3459	Glycosyltransferase 36 associated
NZD86_22030	COG0577	efflux transmembrane transporter activity
NZD86_22030	COG1136	(ABC) transporter
NZD86_22035	COG1136	(ABC) transporter
NZD86_22080	COG1215	transferase activity, transferring glycosyl groups
NZD86_22100	COG0438	transferase activity, transferring glycosyl groups
NZD86_22105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NZD86_22110	COG3328	transposase activity
NZD86_22155	COG0463	Glycosyl transferase, family 2
NZD86_22165	COG1739	Uncharacterized protein family UPF0029
NZD86_22185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NZD86_22190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NZD86_22195	COG4786	Flagellar basal body rod
NZD86_22200	COG1749	Flagellar hook protein flgE
NZD86_22205	COG1077	Cell shape determining protein MreB Mrl
NZD86_22210	COG1609	Transcriptional regulator
NZD86_22215	COG0739	heme binding
NZD86_22220	COG2385	sporulation resulting in formation of a cellular spore
NZD86_22240	COG3852	Histidine kinase
NZD86_22250	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NZD86_22275	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NZD86_22280	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NZD86_22290	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NZD86_22300	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NZD86_22305	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NZD86_22310	COG0356	it plays a direct role in the translocation of protons across the membrane
NZD86_22325	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NZD86_22330	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NZD86_22340	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NZD86_22345	COG4475	Protein of unknown function (DUF436)
NZD86_22350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NZD86_22385	COG1703	isobutyryl-CoA mutase activity
NZD86_22385	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NZD86_22385	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NZD86_22390	COG1309	transcriptional regulator
NZD86_22395	COG0009	L-threonylcarbamoyladenylate synthase
NZD86_22410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NZD86_22415	COG0254	rRNA binding
NZD86_22425	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NZD86_22440	COG0504	CTP synthase activity
NZD86_22445	COG3343	RNA polymerase activity
NZD86_22455	COG1960	acyl-CoA dehydrogenase activity
NZD86_22460	COG1960	acyl-CoA dehydrogenase activity
NZD86_22465	COG1024	Enoyl-CoA hydratase
NZD86_22470	COG1250	3-hydroxyacyl-CoA dehydrogenase
NZD86_22475	COG0183	Belongs to the thiolase family
NZD86_22480	COG0247	lactate metabolic process
NZD86_22480	COG2181	nitrate reductase activity
NZD86_22485	COG1216	Glycosyl transferase, family 2
NZD86_22500	COG0010	Belongs to the arginase family
NZD86_22505	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NZD86_22510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NZD86_22515	COG0436	Aminotransferase
NZD86_22550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NZD86_22555	COG4187	Peptidase family M20/M25/M40
NZD86_22560	COG1803	Methylglyoxal synthase
NZD86_22565	COG0006	proline dipeptidase activity
NZD86_22570	COG2271	Major facilitator Superfamily
NZD86_22575	COG1070	Carbohydrate kinase
NZD86_22580	COG1609	Transcriptional regulator
NZD86_22585	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NZD86_22590	COG0572	uridine kinase
NZD86_22595	COG0813	purine-nucleoside phosphorylase activity
NZD86_22600	COG2171	N-acyltransferase activity
NZD86_22605	COG1473	amidohydrolase
NZD86_22610	COG0436	Aminotransferase
NZD86_22615	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NZD86_22635	COG0390	transport system, permease component
NZD86_22640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NZD86_22645	COG2130	NADP-dependent
NZD86_22650	COG0791	NLP P60 protein
NZD86_22655	COG3483	tryptophan 2,3-dioxygenase activity
NZD86_22660	COG0667	Aldo Keto reductase
NZD86_22665	COG2814	Major facilitator Superfamily
NZD86_22670	COG0640	Transcriptional regulator
NZD86_22680	COG0330	HflC and HflK could
NZD86_22685	COG1725	Transcriptional regulator
NZD86_22695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NZD86_22705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NZD86_22705	COG1796	DNA polymerase
NZD86_22710	COG1278	Cold shock
NZD86_22720	COG0529	Catalyzes the synthesis of activated sulfate
NZD86_22740	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NZD86_22755	COG1335	isochorismatase
NZD86_22770	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NZD86_22775	COG2267	carboxylic ester hydrolase activity
NZD86_22780	COG0488	(ABC) transporter
NZD86_22785	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NZD86_22800	COG5577	PFAM Coat F domain
NZD86_22820	COG1012	belongs to the aldehyde dehydrogenase family
NZD86_22840	COG0288	reversible hydration of carbon dioxide
NZD86_22845	COG0726	polysaccharide deacetylase
NZD86_22860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NZD86_22865	COG0352	thiamine-phosphate diphosphorylase activity
NZD86_22870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NZD86_22880	COG2022	thiamine diphosphate biosynthetic process
NZD86_22885	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NZD86_22895	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NZD86_22925	COG3344	reverse transcriptase
NZD86_22945	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NZD86_22950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NZD86_22955	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NZD86_22970	COG5002	protein histidine kinase activity
NZD86_22985	COG0305	Participates in initiation and elongation during chromosome replication
NZD86_22990	COG0359	binds to the 23S rRNA
NZD86_23000	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NZD86_23005	COG0629	single-stranded DNA binding
NZD86_23010	COG0360	Binds together with S18 to 16S ribosomal RNA
NZD86_23015	COG0012	GTP binding
NZD86_23020	COG0243	molybdopterin cofactor binding
NZD86_23025	COG4481	Protein conserved in bacteria
NZD86_23030	COG0668	transmembrane transport
NZD86_23050	COG1811	Na channel or pump
NZD86_23055	COG1475	DNA binding
NZD86_23060	COG1192	Involved in chromosome partitioning
NZD86_23075	COG0445	tRNA wobble uridine modification
NZD86_23080	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NZD86_23085	COG1847	R3H domain protein
NZD86_23090	COG0706	membrane insertase activity
NZD86_23095	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NZD86_23105	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NZD86_23110	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NZD86_23115	COG2267	carboxylic ester hydrolase activity
NZD86_23125	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NZD86_23130	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NZD86_23135	COG1733	regulation of RNA biosynthetic process
NZD86_23145	COG3383	formate dehydrogenase (NAD+) activity
NZD86_23150	COG2427	Protein of unknown function (DUF1641)
NZD86_23180	COG5337	Spore coat protein CotH
NZD86_23200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NZD86_23205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NZD86_23215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NZD86_23220	COG2318	DinB family
NZD86_23245	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_23265	COG0385	Bile acid
NZD86_23280	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NZD86_23285	COG3395	kinase activity
NZD86_23290	COG1609	Transcriptional regulator
NZD86_23295	COG3961	Belongs to the TPP enzyme family
NZD86_23305	COG1846	Transcriptional regulator
NZD86_23320	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_23355	COG0789	Transcriptional regulator
NZD86_23375	COG0789	Transcriptional regulator
NZD86_23390	COG1309	transcriptional regulator
NZD86_23405	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_23410	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_23430	COG4221	oxidoreductase activity
NZD86_23440	COG2207	Transcriptional regulator
NZD86_23440	COG0662	Cupin 2, conserved barrel domain protein
NZD86_23465	COG1063	alcohol dehydrogenase
NZD86_23475	COG5577	PFAM Coat F domain
NZD86_23490	COG1215	transferase activity, transferring glycosyl groups
NZD86_23495	COG0438	transferase activity, transferring glycosyl groups
NZD86_23510	COG3511	phospholipase C
NZD86_23525	COG1309	transcriptional regulator
NZD86_23530	COG1741	Belongs to the pirin family
NZD86_23535	COG0531	amino acid
NZD86_23555	COG2249	NAD(P)H dehydrogenase (quinone) activity
NZD86_23565	COG0179	Fumarylacetoacetate (FAA) hydrolase
NZD86_23575	COG2267	carboxylic ester hydrolase activity
NZD86_23580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NZD86_23630	COG3547	Transposase (IS116 IS110 IS902 family)
NZD86_23650	COG3267	Type II secretory pathway component ExeA
NZD86_23650	COG3409	Peptidoglycan-binding domain 1 protein
NZD86_23685	COG1172	Belongs to the binding-protein-dependent transport system permease family
NZD86_23690	COG1129	ABC transporter
NZD86_23695	COG1879	ABC-type sugar transport system periplasmic component
NZD86_23715	COG2188	Transcriptional regulator
NZD86_23720	COG1070	Carbohydrate kinase
NZD86_23730	COG1349	DNA-binding transcription factor activity
NZD86_23735	COG1349	DNA-binding transcription factor activity
NZD86_23740	COG3395	kinase activity
NZD86_23745	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NZD86_23750	COG2271	Major facilitator Superfamily
NZD86_23795	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NZD86_23800	COG0708	Exodeoxyribonuclease III
NZD86_23810	COG1414	Transcriptional regulator
NZD86_23815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NZD86_23830	COG0179	Fumarylacetoacetate (FAA) hydrolase
NZD86_23845	COG2814	Major facilitator Superfamily
NZD86_23865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NZD86_23880	COG1278	Cold shock
NZD86_23930	COG1192	Involved in chromosome partitioning
NZD86_23955	COG0840	transmembrane signaling receptor activity
NZD86_23990	COG0739	heme binding
NZD86_24030	COG0531	amino acid
NZD86_24070	COG3385	transposase activity
NZD86_24165	COG0556	nucleotide-excision repair
NZD86_24180	COG1278	Cold shock
NZD86_24230	COG1192	Involved in chromosome partitioning
NZD86_24255	COG0840	transmembrane signaling receptor activity
NZD86_24290	COG0739	heme binding
NZD86_24330	COG0531	amino acid
NZD86_24370	COG3385	transposase activity
NZD86_24465	COG0556	nucleotide-excision repair
NZD86_24480	COG1278	Cold shock