locus-tag	class	description
JZ786_00005	COG1797	cobyrinic acid a,c-diamide synthase activity
JZ786_00010	COG0588	phosphoglycerate mutase activity
JZ786_00015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JZ786_00020	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JZ786_00025	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JZ786_00030	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
JZ786_00035	COG1120	ATPase activity
JZ786_00045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JZ786_00055	COG2096	Adenosyltransferase
JZ786_00060	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JZ786_00150	COG0463	Glycosyl transferase, family 2
JZ786_00155	COG0457	Tetratricopeptide repeat
JZ786_00155	COG0463	Glycosyl transferase, family 2
JZ786_00175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JZ786_00180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JZ786_00190	COG1216	Glycosyl transferase, family 2
JZ786_00195	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JZ786_00200	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JZ786_00210	COG1216	Glycosyl transferase, family 2
JZ786_00230	COG0438	transferase activity, transferring glycosyl groups
JZ786_00235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JZ786_00245	COG0577	efflux transmembrane transporter activity
JZ786_00245	COG1136	(ABC) transporter
JZ786_00250	COG1136	(ABC) transporter
JZ786_00250	COG0577	efflux transmembrane transporter activity
JZ786_00290	COG0463	Glycosyl transferase, family 2
JZ786_00310	COG1739	Uncharacterized protein family UPF0029
JZ786_00330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JZ786_00340	COG1216	Glycosyl transferase, family 2
JZ786_00380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JZ786_00390	COG0477	Major facilitator Superfamily
JZ786_00410	COG4786	Flagellar basal body rod
JZ786_00415	COG1077	Cell shape determining protein MreB Mrl
JZ786_00420	COG1609	Transcriptional regulator
JZ786_00425	COG0739	heme binding
JZ786_00430	COG2385	sporulation resulting in formation of a cellular spore
JZ786_00440	COG2323	membrane
JZ786_00445	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JZ786_00465	COG1007	ATP synthesis coupled electron transport
JZ786_00470	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JZ786_00475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JZ786_00490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JZ786_00495	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JZ786_00500	COG0649	NAD binding
JZ786_00505	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JZ786_00510	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JZ786_00515	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JZ786_00525	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JZ786_00530	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JZ786_00535	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JZ786_00540	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JZ786_00545	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JZ786_00545	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JZ786_00555	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JZ786_00560	COG0356	it plays a direct role in the translocation of protons across the membrane
JZ786_00575	COG0183	Belongs to the thiolase family
JZ786_00580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JZ786_00585	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JZ786_00590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JZ786_00595	COG2814	Major facilitator Superfamily
JZ786_00610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JZ786_00620	COG0698	ribose 5-phosphate isomerase
JZ786_00625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JZ786_00635	COG0009	L-threonylcarbamoyladenylate synthase
JZ786_00645	COG2890	protein-(glutamine-N5) methyltransferase activity
JZ786_00650	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JZ786_00655	COG0254	rRNA binding
JZ786_00660	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JZ786_00665	COG1494	fructose-1,6-bisphosphatase
JZ786_00670	COG0436	Aminotransferase
JZ786_00675	COG1473	amidohydrolase
JZ786_00680	COG2171	N-acyltransferase activity
JZ786_00685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JZ786_00690	COG3246	L-lysine catabolic process to acetate
JZ786_00695	COG1607	acyl-coa hydrolase
JZ786_00700	COG2204	response regulator
JZ786_00705	COG0504	CTP synthase activity
JZ786_00710	COG3343	RNA polymerase activity
JZ786_00720	COG1960	acyl-CoA dehydrogenase activity
JZ786_00725	COG1960	acyl-CoA dehydrogenase activity
JZ786_00730	COG1024	Enoyl-CoA hydratase
JZ786_00735	COG1250	3-hydroxyacyl-CoA dehydrogenase
JZ786_00745	COG0183	Belongs to the thiolase family
JZ786_00750	COG2181	nitrate reductase activity
JZ786_00750	COG0247	lactate metabolic process
JZ786_00755	COG1126	abc transporter atp-binding protein
JZ786_00760	COG0765	amino acid transport
JZ786_00765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JZ786_00780	COG2186	Transcriptional regulator
JZ786_00785	COG0277	FAD linked oxidase domain protein
JZ786_00790	COG0247	lactate metabolic process
JZ786_00800	COG2188	Transcriptional regulator
JZ786_00820	COG5012	cobalamin binding
JZ786_00825	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JZ786_00830	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JZ786_00840	COG1509	lysine 2,3-aminomutase activity
JZ786_00845	COG0604	alcohol dehydrogenase
JZ786_00850	COG3829	transcription factor binding
JZ786_00860	COG0010	Belongs to the arginase family
JZ786_00865	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JZ786_00870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JZ786_00900	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_00915	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JZ786_00920	COG1854	S-ribosylhomocysteine lyase activity
JZ786_00925	COG0646	methionine synthase
JZ786_00925	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JZ786_00930	COG0646	methionine synthase
JZ786_00930	COG1410	methionine synthase
JZ786_00960	COG0006	proline dipeptidase activity
JZ786_00970	COG2068	MobA-Related Protein
JZ786_00995	COG2255	four-way junction helicase activity
JZ786_01005	COG1119	ATPase activity
JZ786_01010	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JZ786_01015	COG0813	purine-nucleoside phosphorylase activity
JZ786_01020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JZ786_01025	COG1584	GPR1 FUN34 yaaH family protein
JZ786_01040	COG1388	LysM domain
JZ786_01040	COG3858	chitin binding
JZ786_01055	COG2706	6-phosphogluconolactonase activity
JZ786_01070	COG2391	methyltransferase activity
JZ786_01090	COG2363	Small membrane protein
JZ786_01105	COG0673	inositol 2-dehydrogenase activity
JZ786_01120	COG0673	inositol 2-dehydrogenase activity
JZ786_01125	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JZ786_01125	COG1796	DNA polymerase
JZ786_01130	COG0726	polysaccharide deacetylase
JZ786_01140	COG3383	formate dehydrogenase (NAD+) activity
JZ786_01145	COG0569	domain protein
JZ786_01145	COG0475	glutathione-regulated potassium exporter activity
JZ786_01150	COG1070	Carbohydrate kinase
JZ786_01165	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JZ786_01170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JZ786_01175	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JZ786_01190	COG5002	protein histidine kinase activity
JZ786_01195	COG0745	RESPONSE REGULATOR receiver
JZ786_01210	COG0305	Participates in initiation and elongation during chromosome replication
JZ786_01215	COG0359	binds to the 23S rRNA
JZ786_01235	COG0629	single-stranded DNA binding
JZ786_01240	COG0360	Binds together with S18 to 16S ribosomal RNA
JZ786_01245	COG0012	GTP binding
JZ786_01250	COG0243	molybdopterin cofactor binding
JZ786_01255	COG4481	Protein conserved in bacteria
JZ786_01285	COG1811	Na channel or pump
JZ786_01290	COG1475	DNA binding
JZ786_01295	COG1192	Involved in chromosome partitioning
JZ786_01300	COG1475	DNA binding
JZ786_01310	COG0445	tRNA wobble uridine modification
JZ786_01315	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JZ786_01320	COG1847	R3H domain protein
JZ786_01325	COG0706	membrane insertase activity
JZ786_01335	COG0594	ribonuclease P activity
JZ786_01340	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JZ786_01345	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JZ786_01350	COG0592	DNA-directed DNA polymerase activity
JZ786_01355	COG2501	S4 domain
JZ786_01360	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JZ786_01370	COG0187	DNA topoisomerase II activity
JZ786_01375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JZ786_01410	COG0516	GMP reductase activity
JZ786_01410	COG0517	IMP dehydrogenase activity
JZ786_01415	COG1686	Belongs to the peptidase S11 family
JZ786_01420	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JZ786_01425	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JZ786_01435	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JZ786_01455	COG2070	2-Nitropropane dioxygenase
JZ786_01460	COG0656	L-ascorbic acid biosynthetic process
JZ786_01485	COG1252	NADH dehydrogenase
JZ786_01490	COG1960	acyl-CoA dehydrogenase activity
JZ786_01495	COG4191	Histidine kinase
JZ786_01520	COG2766	serine protein kinase
JZ786_01525	COG2719	SpoVR family
JZ786_01540	COG0778	Nitroreductase
JZ786_01545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JZ786_01555	COG0653	protein targeting
JZ786_01580	COG0393	Putative heavy-metal-binding
JZ786_01585	COG0393	Putative heavy-metal-binding
JZ786_01600	COG1289	transmembrane transporter activity
JZ786_01605	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JZ786_01630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JZ786_01650	COG0667	Aldo Keto reductase
JZ786_01660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JZ786_01665	COG0488	(ABC) transporter
JZ786_01675	COG4492	Belongs to the UPF0735 family
JZ786_01680	COG0527	aspartate kinase activity
JZ786_01685	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JZ786_01690	COG1309	transcriptional regulator
JZ786_01705	COG3396	Phenylacetate-CoA oxygenase
JZ786_01720	COG2151	metal-sulfur cluster biosynthetic enzyme
JZ786_01725	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
JZ786_01730	COG0183	Belongs to the thiolase family
JZ786_01735	COG1132	(ABC) transporter
JZ786_01740	COG1132	(ABC) transporter
JZ786_01760	COG0651	ATP synthesis coupled electron transport
JZ786_01765	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JZ786_01775	COG0651	ATP synthesis coupled electron transport
JZ786_01780	COG0649	NAD binding
JZ786_01785	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JZ786_01795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JZ786_01800	COG3584	3D domain protein
JZ786_01800	COG1388	LysM domain
JZ786_01810	COG0492	ferredoxin-NADP+ reductase activity
JZ786_01815	COG2022	thiamine diphosphate biosynthetic process
JZ786_01825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JZ786_01830	COG0352	thiamine-phosphate diphosphorylase activity
JZ786_01835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JZ786_01840	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JZ786_01845	COG0351	phosphomethylpyrimidine kinase
JZ786_01845	COG0352	thiamine-phosphate diphosphorylase activity
JZ786_01850	COG1914	H( )-stimulated, divalent metal cation uptake system
JZ786_01865	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JZ786_01915	COG1388	LysM domain
JZ786_01915	COG3858	chitin binding
JZ786_01925	COG0601	transmembrane transport
JZ786_01930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JZ786_01940	COG4948	Mandelate Racemase Muconate Lactonizing
JZ786_01965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JZ786_01970	COG0444	Belongs to the ABC transporter superfamily
JZ786_01975	COG4608	Belongs to the ABC transporter superfamily
JZ786_01980	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JZ786_01990	COG1472	Belongs to the glycosyl hydrolase 3 family
JZ786_02005	COG2814	Major facilitator Superfamily
JZ786_02030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JZ786_02045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JZ786_02050	COG1917	Cupin 2, conserved barrel domain protein
JZ786_02060	COG0527	aspartate kinase activity
JZ786_02065	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JZ786_02075	COG3973	AAA domain
JZ786_02080	COG2086	electron transfer activity
JZ786_02085	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JZ786_02090	COG0644	oxidoreductase
JZ786_02100	COG3579	cysteine-type endopeptidase activity
JZ786_02110	COG3361	conserved protein (COG2071)
JZ786_02120	COG3011	Protein conserved in bacteria
JZ786_02140	COG2211	Major facilitator Superfamily
JZ786_02145	COG2723	6-phospho-beta-galactosidase activity
JZ786_02150	COG1506	peptidase
JZ786_02150	COG0823	Involved in the tonB-independent uptake of proteins
JZ786_02150	COG4946	Tricorn protease homolog
JZ786_02170	COG0386	Belongs to the glutathione peroxidase family
JZ786_02175	COG0420	3'-5' exonuclease activity
JZ786_02180	COG4717	serine-type aminopeptidase activity
JZ786_02185	COG0427	acetyl-CoA hydrolase
JZ786_02205	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_02215	COG1477	protein flavinylation
JZ786_02230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JZ786_02235	COG0584	glycerophosphoryl diester phosphodiesterase
JZ786_02245	COG2146	nitrite reductase [NAD(P)H] activity
JZ786_02260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JZ786_02270	COG0662	Cupin 2, conserved barrel domain protein
JZ786_02275	COG1686	Belongs to the peptidase S11 family
JZ786_02280	COG4191	Histidine kinase
JZ786_02285	COG0492	ferredoxin-NADP+ reductase activity
JZ786_02290	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JZ786_02320	COG3344	reverse transcriptase
JZ786_02330	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JZ786_02335	COG1615	UPF0182 protein
JZ786_02340	COG0367	asparagine synthase
JZ786_02360	COG3852	Histidine kinase
JZ786_02365	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JZ786_02370	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JZ786_02375	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JZ786_02390	COG2244	polysaccharide biosynthetic process
JZ786_02410	COG1982	Orn Lys Arg decarboxylase major
JZ786_02415	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JZ786_02420	COG3870	Protein conserved in bacteria
JZ786_02430	COG1774	PSP1 C-terminal conserved region
JZ786_02435	COG4467	Involved in initiation control of chromosome replication
JZ786_02440	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JZ786_02445	COG2002	toxin-antitoxin pair type II binding
JZ786_02455	COG0084	hydrolase, TatD family'
JZ786_02465	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JZ786_02470	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
JZ786_02485	COG4466	Protein conserved in bacteria
JZ786_02495	COG4242	Belongs to the peptidase S51 family
JZ786_02500	COG0189	ligase activity
JZ786_02500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JZ786_02510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JZ786_02515	COG0251	oxidation-reduction process
JZ786_02520	COG2088	sporulation resulting in formation of a cellular spore
JZ786_02525	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JZ786_02530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JZ786_02535	COG0193	aminoacyl-tRNA hydrolase activity
JZ786_02545	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JZ786_02550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JZ786_02555	COG2002	toxin-antitoxin pair type II binding
JZ786_02560	COG2244	polysaccharide biosynthetic process
JZ786_02565	COG3956	TIGRFAM MazG family protein
JZ786_02570	COG0776	regulation of translation
JZ786_02575	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JZ786_02595	COG1098	S1 RNA binding domain
JZ786_02615	COG0717	Belongs to the dCTP deaminase family
JZ786_02620	COG2208	phosphoserine phosphatase activity
JZ786_02625	COG2304	oxidoreductase activity
JZ786_02630	COG0515	serine threonine protein kinase
JZ786_02635	COG0037	tRNA processing
JZ786_02645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JZ786_02655	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JZ786_02665	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JZ786_02670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JZ786_02675	COG1396	sequence-specific DNA binding
JZ786_02680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JZ786_02715	COG1309	transcriptional regulator
JZ786_02720	COG4463	regulation of RNA biosynthetic process
JZ786_02725	COG3880	PFAM UvrB UvrC protein
JZ786_02730	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JZ786_02735	COG0542	response to heat
JZ786_02740	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JZ786_02745	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JZ786_02750	COG1183	phosphatidylcholine synthase activity
JZ786_02755	COG4956	integral membrane protein (PIN domain superfamily)
JZ786_02765	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JZ786_02770	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JZ786_02775	COG0215	cysteine-tRNA ligase activity
JZ786_02785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JZ786_02790	COG3688	RNA-binding protein containing a PIN domain
JZ786_02810	COG0250	Participates in transcription elongation, termination and antitermination
JZ786_02820	COG0081	regulation of translation
JZ786_02825	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JZ786_02830	COG0222	ribosome binding
JZ786_02835	COG2813	Specifically methylates the guanine in position
JZ786_02840	COG0085	RNA polymerase activity
JZ786_02845	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JZ786_02850	COG1358	cellular component organization or biogenesis
JZ786_02855	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JZ786_02860	COG0049	tRNA binding
JZ786_02865	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JZ786_02880	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JZ786_02890	COG0089	rRNA binding
JZ786_02895	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JZ786_02900	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JZ786_02905	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JZ786_02910	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JZ786_02915	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JZ786_02920	COG0255	Belongs to the universal ribosomal protein uL29 family
JZ786_02925	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JZ786_02930	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JZ786_02940	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JZ786_02945	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JZ786_02950	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JZ786_02955	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JZ786_02960	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JZ786_02965	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JZ786_02970	COG1841	ribosomal large subunit assembly
JZ786_02975	COG0200	Binds to the 23S rRNA
JZ786_02980	COG0201	protein transport
JZ786_02985	COG0563	adenylate kinase activity
JZ786_02995	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JZ786_03000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JZ786_03005	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JZ786_03010	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JZ786_03015	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JZ786_03020	COG0202	RNA polymerase activity
JZ786_03025	COG0203	ribosomal protein L17
JZ786_03030	COG0101	tRNA pseudouridine synthase activity
JZ786_03035	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JZ786_03040	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JZ786_03045	COG0860	N-Acetylmuramoyl-L-alanine amidase
JZ786_03055	COG0489	protein tyrosine kinase activity
JZ786_03090	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JZ786_03100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JZ786_03105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JZ786_03150	COG0697	spore germination
JZ786_03175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JZ786_03180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JZ786_03185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JZ786_03205	COG3384	dioxygenase
JZ786_03210	COG1132	(ABC) transporter
JZ786_03215	COG1132	(ABC) transporter
JZ786_03230	COG2217	Heavy metal translocating P-type atpase
JZ786_03235	COG1937	Protein conserved in bacteria
JZ786_03245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JZ786_03310	COG1595	DNA-templated transcription, initiation
JZ786_03330	COG0656	L-ascorbic acid biosynthetic process
JZ786_03335	COG1606	tRNA processing
JZ786_03340	COG1691	(AIR) carboxylase
JZ786_03350	COG0095	Lipoate-protein ligase
JZ786_03375	COG2226	methyltransferase
JZ786_03380	COG1846	Transcriptional regulator
JZ786_03395	COG3842	ATPase activity
JZ786_03435	COG0427	acetyl-CoA hydrolase
JZ786_03440	COG3279	Response regulator of the LytR AlgR family
JZ786_03450	COG2827	Endonuclease containing a URI domain
JZ786_03460	COG0697	spore germination
JZ786_03470	COG1234	tRNA 3'-trailer cleavage
JZ786_03475	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JZ786_03480	COG0390	transport system, permease component
JZ786_03485	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_03490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JZ786_03505	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JZ786_03520	COG1388	LysM domain
JZ786_03520	COG0791	NLP P60 protein
JZ786_03535	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_03545	COG0681	Belongs to the peptidase S26 family
JZ786_03550	COG0667	Aldo Keto reductase
JZ786_03585	COG0657	acetylesterase activity
JZ786_03600	COG3459	Glycosyltransferase 36 associated
JZ786_03605	COG0569	domain protein
JZ786_03605	COG0475	glutathione-regulated potassium exporter activity
JZ786_03625	COG1216	Glycosyl transferase, family 2
JZ786_03630	COG0604	alcohol dehydrogenase
JZ786_03635	COG0697	spore germination
JZ786_03640	COG1122	ATPase activity
JZ786_03645	COG1122	ATPase activity
JZ786_03650	COG1268	BioY protein
JZ786_03685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JZ786_03690	COG0521	Mo-molybdopterin cofactor biosynthetic process
JZ786_03705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JZ786_03710	COG1278	Cold shock
JZ786_03730	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JZ786_03735	COG4585	Histidine kinase
JZ786_03755	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JZ786_03755	COG2199	diguanylate cyclase activity
JZ786_03760	COG1307	EDD domain protein, DegV family
JZ786_03765	COG1040	competence protein
JZ786_03800	COG1191	sigma factor activity
JZ786_03815	COG4786	Flagellar basal body rod
JZ786_03815	COG1256	bacterial-type flagellum assembly
JZ786_03840	COG0457	Tetratricopeptide repeat
JZ786_03840	COG0463	Glycosyl transferase, family 2
JZ786_03845	COG0438	transferase activity, transferring glycosyl groups
JZ786_03860	COG2226	methyltransferase
JZ786_03865	COG4786	Flagellar basal body rod
JZ786_03870	COG4786	Flagellar basal body rod
JZ786_03880	COG0653	protein targeting
JZ786_03890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JZ786_03935	COG4948	Mandelate Racemase Muconate Lactonizing
JZ786_03955	COG2197	response regulator
JZ786_04000	COG2884	Cell division ATP-binding protein ftsE
JZ786_04005	COG2177	Part of the ABC transporter FtsEX involved in
JZ786_04010	COG0793	Belongs to the peptidase S41A family
JZ786_04010	COG3409	Peptidoglycan-binding domain 1 protein
JZ786_04020	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JZ786_04030	COG0556	nucleotide-excision repair
JZ786_04035	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JZ786_04040	COG3835	regulator
JZ786_04045	COG3842	ATPase activity
JZ786_04050	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JZ786_04055	COG0018	arginyl-trna synthetase
JZ786_04070	COG1051	belongs to the nudix hydrolase family
JZ786_04075	COG1940	carbohydrate kinase activity
JZ786_04080	COG1660	Displays ATPase and GTPase activities
JZ786_04085	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JZ786_04090	COG1481	regulation of sporulation
JZ786_04095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JZ786_04115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JZ786_04120	COG1194	a g-specific adenine glycosylase
JZ786_04125	COG0670	Belongs to the BI1 family
JZ786_04130	COG0495	leucyl-tRNA aminoacylation
JZ786_04135	COG2186	Transcriptional regulator
JZ786_04165	COG1205	dead DEAH box helicase
JZ786_04165	COG1111	helicase
JZ786_04170	COG3359	exonuclease
JZ786_04175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JZ786_04180	COG4493	Belongs to the UPF0637 family
JZ786_04190	COG0737	Belongs to the 5'-nucleotidase family
JZ786_04195	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JZ786_04210	COG0697	spore germination
JZ786_04225	COG0328	RNA-DNA hybrid ribonuclease activity
JZ786_04230	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JZ786_04235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JZ786_04245	COG0473	3-isopropylmalate dehydrogenase activity
JZ786_04250	COG1414	Transcriptional regulator
JZ786_04295	COG2766	serine protein kinase
JZ786_04300	COG2718	Belongs to the UPF0229 family
JZ786_04305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JZ786_04325	COG2718	Belongs to the UPF0229 family
JZ786_04335	COG1506	peptidase
JZ786_04335	COG0823	Involved in the tonB-independent uptake of proteins
JZ786_04335	COG4946	Tricorn protease homolog
JZ786_04340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JZ786_04345	COG3852	Histidine kinase
JZ786_04365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JZ786_04385	COG2259	Doxx family
JZ786_04400	COG1802	Transcriptional regulator
JZ786_04415	COG2814	Major facilitator Superfamily
JZ786_04420	COG0385	Bile acid
JZ786_04425	COG1802	Transcriptional regulator
JZ786_04430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JZ786_04435	COG1024	Enoyl-CoA hydratase
JZ786_04445	COG0697	spore germination
JZ786_04455	COG2719	SpoVR family
JZ786_04475	COG0596	Alpha beta hydrolase
JZ786_04495	COG0242	peptide deformylase activity
JZ786_04560	COG2059	Chromate
JZ786_04565	COG2059	Chromate
JZ786_04575	COG0668	transmembrane transport
JZ786_04585	COG2323	membrane
JZ786_04595	COG1960	acyl-CoA dehydrogenase activity
JZ786_04660	COG2224	Isocitrate lyase
JZ786_04665	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JZ786_04670	COG0367	asparagine synthase
JZ786_04675	COG0745	RESPONSE REGULATOR receiver
JZ786_04680	COG5002	protein histidine kinase activity
JZ786_04685	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JZ786_04690	COG1846	Transcriptional regulator
JZ786_04695	COG2814	Major facilitator Superfamily
JZ786_04700	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JZ786_04710	COG0674	pyruvate-flavodoxin oxidoreductase activity
JZ786_04710	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JZ786_04715	COG1013	pyruvate-flavodoxin oxidoreductase activity
JZ786_04720	COG0427	acetyl-CoA hydrolase
JZ786_04725	COG0535	radical SAM domain protein
JZ786_04750	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JZ786_04755	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JZ786_04760	COG1984	allophanate hydrolase subunit 2
JZ786_04765	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JZ786_04770	COG3118	belongs to the thioredoxin family
JZ786_04775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JZ786_04780	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JZ786_04785	COG1850	ribulose-bisphosphate carboxylase activity
JZ786_04795	COG0235	Class ii aldolase
JZ786_04820	COG0583	DNA-binding transcription factor activity
JZ786_04825	COG2814	Major facilitator Superfamily
JZ786_04885	COG1733	regulation of RNA biosynthetic process
JZ786_04890	COG0745	RESPONSE REGULATOR receiver
JZ786_04940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JZ786_04950	COG0154	amidase activity
JZ786_04955	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JZ786_04960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JZ786_05055	COG2201	protein-glutamate methylesterase activity
JZ786_05070	COG3437	response regulator, receiver
JZ786_05115	COG2199	diguanylate cyclase activity
JZ786_05230	COG2808	Putative FMN-binding domain
JZ786_05250	COG0697	spore germination
JZ786_05360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JZ786_05440	COG0346	lactoylglutathione lyase activity
JZ786_05480	COG1595	DNA-templated transcription, initiation
JZ786_05520	COG1595	DNA-templated transcription, initiation
JZ786_05610	COG1388	LysM domain
JZ786_05625	COG2856	Zn peptidase
JZ786_05650	COG1396	sequence-specific DNA binding
JZ786_05660	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
JZ786_05670	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JZ786_05675	COG0515	serine threonine protein kinase
JZ786_05685	COG0706	membrane insertase activity
JZ786_05700	COG1695	Transcriptional regulator
JZ786_05900	COG0730	response to heat
JZ786_05905	COG0425	Belongs to the sulfur carrier protein TusA family
JZ786_05910	COG2210	Belongs to the sulfur carrier protein TusA family
JZ786_05935	COG2323	membrane
JZ786_05945	COG1937	Protein conserved in bacteria
JZ786_05950	COG0446	pyridine nucleotide-disulphide oxidoreductase
JZ786_05965	COG0460	homoserine dehydrogenase
JZ786_05975	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JZ786_05985	COG0129	dihydroxy-acid dehydratase activity
JZ786_05990	COG0028	Belongs to the TPP enzyme family
JZ786_05995	COG0440	acetolactate synthase activity
JZ786_06000	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JZ786_06005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JZ786_06015	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JZ786_06020	COG0066	3-isopropylmalate dehydratase activity
JZ786_06025	COG0456	acetyltransferase
JZ786_06040	COG0477	Major facilitator Superfamily
JZ786_06090	COG1914	H( )-stimulated, divalent metal cation uptake system
JZ786_06095	COG3344	reverse transcriptase
JZ786_06100	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JZ786_06115	COG3344	reverse transcriptase
JZ786_06120	COG3848	Pyruvate phosphate dikinase
JZ786_06120	COG0574	Belongs to the PEP-utilizing enzyme family
JZ786_06130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JZ786_06145	COG0697	spore germination
JZ786_06165	COG5002	protein histidine kinase activity
JZ786_06170	COG0745	RESPONSE REGULATOR receiver
JZ786_06175	COG1595	DNA-templated transcription, initiation
JZ786_06185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JZ786_06200	COG0436	Aminotransferase
JZ786_06205	COG1131	(ABC) transporter
JZ786_06215	COG0019	diaminopimelate decarboxylase activity
JZ786_06250	COG1164	Oligoendopeptidase f
JZ786_06260	COG5002	protein histidine kinase activity
JZ786_06265	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JZ786_06270	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JZ786_06285	COG0126	phosphoglycerate kinase activity
JZ786_06290	COG0149	triose-phosphate isomerase activity
JZ786_06295	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JZ786_06300	COG0148	phosphopyruvate hydratase activity
JZ786_06305	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JZ786_06315	COG0557	exoribonuclease II activity
JZ786_06320	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JZ786_06385	COG0517	IMP dehydrogenase activity
JZ786_06390	COG4974	Belongs to the 'phage' integrase family
JZ786_06410	COG0582	viral genome integration into host DNA
JZ786_06420	COG4974	Belongs to the 'phage' integrase family
JZ786_06450	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JZ786_06455	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JZ786_06475	COG1648	precorrin-2 dehydrogenase activity
JZ786_06475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JZ786_06525	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JZ786_06530	COG1648	precorrin-2 dehydrogenase activity
JZ786_06530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JZ786_06540	COG1492	cobalamin metabolic process
JZ786_06575	COG4454	pyrroloquinoline quinone binding
JZ786_06585	COG0640	Transcriptional regulator
JZ786_06595	COG0500	methyltransferase
JZ786_06595	COG3615	Tellurite resistance protein tehB
JZ786_06630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JZ786_06640	COG2002	toxin-antitoxin pair type II binding
JZ786_06645	COG5002	protein histidine kinase activity
JZ786_06655	COG3706	GGDEF domain
JZ786_06675	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JZ786_06685	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JZ786_06730	COG3344	reverse transcriptase
JZ786_06735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JZ786_06740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JZ786_06770	COG0697	spore germination
JZ786_06785	COG4974	Belongs to the 'phage' integrase family
JZ786_06790	COG4974	Belongs to the 'phage' integrase family
JZ786_06795	COG4974	Belongs to the 'phage' integrase family
JZ786_06800	COG4974	Belongs to the 'phage' integrase family
JZ786_06805	COG0517	IMP dehydrogenase activity
JZ786_06835	COG2814	Major facilitator Superfamily
JZ786_06850	COG1396	sequence-specific DNA binding
JZ786_06930	COG2132	Multicopper oxidase
JZ786_06955	COG0785	Cytochrome C biogenesis protein
JZ786_06960	COG5002	protein histidine kinase activity
JZ786_06970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JZ786_06975	COG1842	Phage shock protein A
JZ786_06985	COG2132	Multicopper oxidase
JZ786_07015	COG2217	Heavy metal translocating P-type atpase
JZ786_07020	COG1937	Protein conserved in bacteria
JZ786_07060	COG1842	Phage shock protein A
JZ786_07070	COG0745	RESPONSE REGULATOR receiver
JZ786_07075	COG5002	protein histidine kinase activity
JZ786_07100	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JZ786_07110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JZ786_07125	COG0477	Major facilitator Superfamily
JZ786_07240	COG4372	Transposase
JZ786_07260	COG1595	DNA-templated transcription, initiation
JZ786_07300	COG1484	DNA-dependent DNA replication
JZ786_07305	COG4584	PFAM Integrase catalytic
JZ786_07340	COG0210	DNA helicase
JZ786_07415	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JZ786_07430	COG0592	DNA-directed DNA polymerase activity
JZ786_07445	COG2003	Belongs to the UPF0758 family
JZ786_07500	COG0406	alpha-ribazole phosphatase activity
JZ786_07505	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JZ786_07510	COG2096	Adenosyltransferase
JZ786_07520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JZ786_07525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JZ786_07540	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JZ786_07545	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JZ786_07555	COG0588	phosphoglycerate mutase activity
JZ786_07610	COG0640	Transcriptional regulator
JZ786_07615	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JZ786_07620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JZ786_07635	COG1742	UPF0060 membrane protein
JZ786_07675	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JZ786_07680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JZ786_07700	COG0697	spore germination
JZ786_07715	COG1278	Cold shock
JZ786_07725	COG3239	Fatty acid desaturase
JZ786_07760	COG0514	ATP-dependent DNA helicase (RecQ)
JZ786_07780	COG1609	Transcriptional regulator
JZ786_07795	COG0235	Class ii aldolase
JZ786_07800	COG2160	L-arabinose isomerase activity
JZ786_07805	COG1657	PFAM Prenyltransferase squalene oxidase
JZ786_07810	COG0438	transferase activity, transferring glycosyl groups
JZ786_07855	COG3858	chitin binding
JZ786_07855	COG1388	LysM domain
JZ786_07860	COG0708	Exodeoxyribonuclease III
JZ786_07865	COG0667	Aldo Keto reductase
JZ786_07870	COG0601	transmembrane transport
JZ786_07875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JZ786_07880	COG2814	Major facilitator Superfamily
JZ786_07895	COG0488	(ABC) transporter
JZ786_07905	COG1970	mechanosensitive ion channel activity
JZ786_07910	COG0667	Aldo Keto reductase
JZ786_07915	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
JZ786_07920	COG0640	Transcriptional regulator
JZ786_07925	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JZ786_07930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JZ786_07940	COG2239	Acts as a magnesium transporter
JZ786_07950	COG1131	(ABC) transporter
JZ786_07955	COG0842	Transport permease protein
JZ786_07990	COG0316	Belongs to the HesB IscA family
JZ786_08015	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JZ786_08020	COG0077	Prephenate dehydratase
JZ786_08020	COG1605	Chorismate mutase
JZ786_08060	COG2966	Psort location CytoplasmicMembrane, score
JZ786_08070	COG1215	transferase activity, transferring glycosyl groups
JZ786_08075	COG0477	Major facilitator Superfamily
JZ786_08085	COG0277	FAD linked oxidase domain protein
JZ786_08090	COG0247	lactate metabolic process
JZ786_08095	COG0277	FAD linked oxidase domain protein
JZ786_08110	COG0667	Aldo Keto reductase
JZ786_08125	COG3239	Fatty acid desaturase
JZ786_08140	COG0720	synthase
JZ786_08150	COG0004	ammonium transporteR
JZ786_08155	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JZ786_08160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JZ786_08165	COG2814	Major facilitator Superfamily
JZ786_08170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JZ786_08175	COG2124	cytochrome p450
JZ786_08185	COG2814	Major facilitator Superfamily
JZ786_08190	COG0288	reversible hydration of carbon dioxide
JZ786_08220	COG0174	glutamine synthetase
JZ786_08225	COG2814	Major facilitator Superfamily
JZ786_08245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JZ786_08255	COG0667	Aldo Keto reductase
JZ786_08260	COG1902	pentaerythritol trinitrate reductase activity
JZ786_08280	COG0444	Belongs to the ABC transporter superfamily
JZ786_08285	COG4608	Belongs to the ABC transporter superfamily
JZ786_08295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JZ786_08300	COG0601	transmembrane transport
JZ786_08305	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JZ786_08310	COG0531	amino acid
JZ786_08315	COG0791	NLP P60 protein
JZ786_08325	COG0281	malic enzyme
JZ786_08335	COG0697	spore germination
JZ786_08390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JZ786_08395	COG0183	Belongs to the thiolase family
JZ786_08410	COG4187	Peptidase family M20/M25/M40
JZ786_08415	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JZ786_08440	COG1116	anion transmembrane transporter activity
JZ786_08445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JZ786_08450	COG0492	ferredoxin-NADP+ reductase activity
JZ786_08465	COG1053	succinate dehydrogenase
JZ786_08470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JZ786_08475	COG0456	acetyltransferase
JZ786_08495	COG0596	Alpha beta hydrolase
JZ786_08500	COG2183	response to ionizing radiation
JZ786_08505	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JZ786_08515	COG1131	(ABC) transporter
JZ786_08520	COG2755	lipolytic protein G-D-S-L family
JZ786_08525	COG2267	carboxylic ester hydrolase activity
JZ786_08535	COG1230	cation diffusion facilitator family transporter
JZ786_08545	COG1607	acyl-coa hydrolase
JZ786_08550	COG0667	Aldo Keto reductase
JZ786_08555	COG1164	Oligoendopeptidase f
JZ786_08560	COG1937	Protein conserved in bacteria
JZ786_08565	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JZ786_08575	COG2818	Glycosylase
JZ786_08580	COG0444	Belongs to the ABC transporter superfamily
JZ786_08585	COG4608	Belongs to the ABC transporter superfamily
JZ786_08590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JZ786_08595	COG0601	transmembrane transport
JZ786_08600	COG0747	negative chemotaxis
JZ786_08605	COG0508	dehydrogenase complex catalyzes the overall conversion of
JZ786_08615	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JZ786_08620	COG4846	Membrane protein involved in cytochrome C biogenesis
JZ786_08625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JZ786_08630	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JZ786_08640	COG3253	May function as heme-dependent peroxidase
JZ786_08650	COG0424	maF-like protein
JZ786_08665	COG2233	PERMEase
JZ786_08670	COG0006	proline dipeptidase activity
JZ786_08695	COG2081	HI0933 family
JZ786_08700	COG1979	alcohol dehydrogenase
JZ786_08715	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JZ786_08720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JZ786_08725	COG0116	Belongs to the methyltransferase superfamily
JZ786_08730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JZ786_08755	COG0109	protoheme IX farnesyltransferase activity
JZ786_08775	COG1830	Aldolase
JZ786_08780	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JZ786_08785	COG2258	MOSC domain
JZ786_08790	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JZ786_08795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JZ786_08805	COG0131	Imidazoleglycerol-phosphate dehydratase
JZ786_08810	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JZ786_08815	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JZ786_08820	COG0107	imidazoleglycerol-phosphate synthase activity
JZ786_08825	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JZ786_08825	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JZ786_08825	COG0140	phosphoribosyl-ATP diphosphatase activity
JZ786_08825	COG0140	phosphoribosyl-ATP diphosphatase activity
JZ786_08835	COG0561	phosphatase activity
JZ786_08845	COG4721	ABC-type cobalt transport system, permease component
JZ786_08850	COG1122	ATPase activity
JZ786_08865	COG0583	DNA-binding transcription factor activity
JZ786_08875	COG0482	sulfurtransferase activity
JZ786_08895	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JZ786_08900	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JZ786_08905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JZ786_08930	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JZ786_08945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JZ786_08950	COG1960	acyl-CoA dehydrogenase activity
JZ786_08955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JZ786_08965	COG0438	transferase activity, transferring glycosyl groups
JZ786_08975	COG1213	nucleotidyl transferase
JZ786_08980	COG2873	o-acetylhomoserine
JZ786_08985	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JZ786_08990	COG0460	homoserine dehydrogenase
JZ786_09000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JZ786_09010	COG1022	Amp-dependent synthetase and ligase
JZ786_09015	COG0302	gtp cyclohydrolase
JZ786_09035	COG2155	Conserved Protein
JZ786_09050	COG0564	pseudouridine synthase activity
JZ786_09065	COG1764	response to oxidative stress
JZ786_09070	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JZ786_09085	COG1363	Peptidase, m42
JZ786_09090	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JZ786_09095	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JZ786_09100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JZ786_09110	COG1595	DNA-templated transcription, initiation
JZ786_09130	COG0730	response to heat
JZ786_09145	COG1505	serine-type exopeptidase activity
JZ786_09150	COG1234	tRNA 3'-trailer cleavage
JZ786_09155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JZ786_09160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JZ786_09170	COG1175	transmembrane transport
JZ786_09175	COG3833	ABC-type maltose transport systems, permease component
JZ786_09200	COG0167	dihydroorotate dehydrogenase activity
JZ786_09205	COG1595	DNA-templated transcription, initiation
JZ786_09220	COG0686	Belongs to the AlaDH PNT family
JZ786_09225	COG2151	metal-sulfur cluster biosynthetic enzyme
JZ786_09230	COG0396	ATPase activity
JZ786_09235	COG0719	Fe-S assembly protein
JZ786_09240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JZ786_09245	COG0822	iron-sulfur transferase activity
JZ786_09250	COG0719	Fe-S assembly protein
JZ786_09260	COG1959	2 iron, 2 sulfur cluster binding
JZ786_09270	COG0450	alkyl hydroperoxide reductase
JZ786_09275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JZ786_09280	COG1309	transcriptional regulator
JZ786_09285	COG2086	electron transfer activity
JZ786_09290	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JZ786_09305	COG1506	peptidase
JZ786_09305	COG0823	Involved in the tonB-independent uptake of proteins
JZ786_09305	COG4946	Tricorn protease homolog
JZ786_09315	COG0626	cystathionine gamma-synthase activity
JZ786_09320	COG0114	fumarate hydratase activity
JZ786_09330	COG0483	inositol monophosphate 1-phosphatase activity
JZ786_09335	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JZ786_09340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JZ786_09355	COG0069	glutamate synthase activity
JZ786_09365	COG3185	4-Hydroxyphenylpyruvate dioxygenase
JZ786_09370	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JZ786_09375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JZ786_09410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JZ786_09435	COG0587	DNA-directed DNA polymerase activity
JZ786_09460	COG0564	pseudouridine synthase activity
JZ786_09470	COG0537	adenosine 5'-monophosphoramidase activity
JZ786_09480	COG1024	Enoyl-CoA hydratase
JZ786_09480	COG1250	3-hydroxyacyl-CoA dehydrogenase
JZ786_09485	COG0183	Belongs to the thiolase family
JZ786_09490	COG1960	acyl-CoA dehydrogenase activity
JZ786_09500	COG3584	3D domain protein
JZ786_09505	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JZ786_09510	COG1309	transcriptional regulator
JZ786_09515	COG1703	isobutyryl-CoA mutase activity
JZ786_09515	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JZ786_09515	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JZ786_09520	COG0477	Major facilitator Superfamily
JZ786_09535	COG0612	Peptidase, M16
JZ786_09540	COG0612	Peptidase, M16
JZ786_09545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JZ786_09555	COG2050	protein possibly involved in aromatic compounds catabolism
JZ786_09560	COG0824	Thioesterase
JZ786_09565	COG2323	membrane
JZ786_09575	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_09590	COG1956	GAF domain-containing protein
JZ786_09595	COG1393	Belongs to the ArsC family
JZ786_09610	COG0772	Belongs to the SEDS family
JZ786_09620	COG0584	glycerophosphoryl diester phosphodiesterase
JZ786_09625	COG0772	Belongs to the SEDS family
JZ786_09655	COG1982	Orn Lys Arg decarboxylase major
JZ786_09660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JZ786_09670	COG0316	Belongs to the HesB IscA family
JZ786_09675	COG1078	dGTPase activity
JZ786_09680	COG0586	Pfam SNARE associated Golgi protein
JZ786_09685	COG3377	Domain of unknown function (DUF1805)
JZ786_09690	COG1363	Peptidase, m42
JZ786_09695	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JZ786_09700	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JZ786_09715	COG0494	nUDIX hydrolase
JZ786_09720	COG1013	pyruvate-flavodoxin oxidoreductase activity
JZ786_09725	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JZ786_09725	COG0674	pyruvate-flavodoxin oxidoreductase activity
JZ786_09735	COG3584	3D domain protein
JZ786_09745	COG2346	COG2346, Truncated hemoglobins
JZ786_09760	COG4974	Belongs to the 'phage' integrase family
JZ786_09815	COG0776	regulation of translation
JZ786_09835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JZ786_09860	COG1061	Type III restriction enzyme res subunit
JZ786_09865	COG0494	nUDIX hydrolase
JZ786_09890	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JZ786_09940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JZ786_09945	COG0640	Transcriptional regulator
JZ786_09975	COG2814	Major facilitator Superfamily
JZ786_10075	COG1595	DNA-templated transcription, initiation
JZ786_10085	COG2318	DinB family
JZ786_10105	COG3340	Belongs to the peptidase S51 family
JZ786_10115	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JZ786_10120	COG1609	Transcriptional regulator
JZ786_10125	COG0673	inositol 2-dehydrogenase activity
JZ786_10130	COG1653	transport
JZ786_10135	COG1175	transmembrane transport
JZ786_10140	COG0395	ABC-type sugar transport system, permease component
JZ786_10185	COG1953	Uracil, thiamine, allantoin
JZ786_10200	COG1012	belongs to the aldehyde dehydrogenase family
JZ786_10205	COG0493	'glutamate synthase
JZ786_10210	COG0167	dihydroorotate dehydrogenase activity
JZ786_10225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JZ786_10230	COG0686	Belongs to the AlaDH PNT family
JZ786_10235	COG1012	belongs to the aldehyde dehydrogenase family
JZ786_10240	COG2084	Dehydrogenase
JZ786_10260	COG1139	Iron-sulfur cluster binding protein
JZ786_10265	COG0247	lactate metabolic process
JZ786_10270	COG2186	Transcriptional regulator
JZ786_10275	COG4806	L-rhamnose isomerase
JZ786_10275	COG1070	Carbohydrate kinase
JZ786_10280	COG1070	Carbohydrate kinase
JZ786_10285	COG3347	Dehydrogenase
JZ786_10285	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_10290	COG4952	isomerase
JZ786_10300	COG1349	DNA-binding transcription factor activity
JZ786_10305	COG1476	TRANSCRIPTIONal
JZ786_10330	COG3119	arylsulfatase activity
JZ786_10360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JZ786_10375	COG1609	Transcriptional regulator
JZ786_10385	COG1175	transmembrane transport
JZ786_10390	COG0395	ABC-type sugar transport system, permease component
JZ786_10415	COG1061	Type III restriction enzyme res subunit
JZ786_10435	COG0673	inositol 2-dehydrogenase activity
JZ786_10445	COG1175	transmembrane transport
JZ786_10450	COG0395	ABC-type sugar transport system, permease component
JZ786_10455	COG2188	Transcriptional regulator
JZ786_10465	COG0205	6-phosphofructokinase activity
JZ786_10475	COG1012	belongs to the aldehyde dehydrogenase family
JZ786_10480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JZ786_10485	COG1397	ADP-ribosylglycohydrolase
JZ786_10505	COG0747	negative chemotaxis
JZ786_10515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JZ786_10525	COG1402	creatininase
JZ786_10550	COG0028	Belongs to the TPP enzyme family
JZ786_10555	COG1073	alpha beta
JZ786_10575	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_10580	COG2814	Major facilitator Superfamily
JZ786_10595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JZ786_10600	COG0006	proline dipeptidase activity
JZ786_10610	COG0837	glucose binding
JZ786_10610	COG1737	Transcriptional regulator
JZ786_10615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JZ786_10630	COG0395	ABC-type sugar transport system, permease component
JZ786_10635	COG1940	carbohydrate kinase activity
JZ786_10640	COG1940	carbohydrate kinase activity
JZ786_10650	COG1175	transmembrane transport
JZ786_10655	COG0395	ABC-type sugar transport system, permease component
JZ786_10660	COG2272	Belongs to the type-B carboxylesterase lipase family
JZ786_10665	COG2272	Belongs to the type-B carboxylesterase lipase family
JZ786_10670	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JZ786_10675	COG1024	Enoyl-CoA hydratase
JZ786_10680	COG1012	belongs to the aldehyde dehydrogenase family
JZ786_10685	COG0395	ABC-type sugar transport system, permease component
JZ786_10705	COG1802	Transcriptional regulator
JZ786_10710	COG2079	MmgE PrpD family protein
JZ786_10720	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_10720	COG3321	synthase
JZ786_10720	COG0604	alcohol dehydrogenase
JZ786_10725	COG2271	Major facilitator Superfamily
JZ786_10735	COG0655	NAD(P)H dehydrogenase (quinone) activity
JZ786_10740	COG2814	Major facilitator Superfamily
JZ786_10745	COG0789	Transcriptional regulator
JZ786_10750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JZ786_10750	COG1017	nitric oxide dioxygenase activity
JZ786_10760	COG0653	protein targeting
JZ786_10765	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JZ786_10785	COG0167	dihydroorotate dehydrogenase activity
JZ786_10790	COG0543	2 iron, 2 sulfur cluster binding
JZ786_10795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JZ786_10800	COG2508	Transcriptional regulator
JZ786_10805	COG2814	Major facilitator Superfamily
JZ786_10810	COG0252	asparaginase activity
JZ786_10820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JZ786_10840	COG2271	Major facilitator Superfamily
JZ786_10850	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JZ786_10855	COG4948	Mandelate Racemase Muconate Lactonizing
JZ786_10865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JZ786_10875	COG2843	Capsule synthesis protein
JZ786_10885	COG2508	Transcriptional regulator
JZ786_10885	COG2508	Transcriptional regulator
JZ786_10890	COG1012	belongs to the aldehyde dehydrogenase family
JZ786_10935	COG2186	Transcriptional regulator
JZ786_10950	COG0402	S-adenosylhomocysteine deaminase activity
JZ786_10960	COG0076	glutamate decarboxylase activity
JZ786_10970	COG0671	phosphoesterase, PA-phosphatase related
JZ786_10975	COG0671	phosphoesterase, PA-phosphatase related
JZ786_10980	COG0586	Pfam SNARE associated Golgi protein
JZ786_11000	COG1077	Cell shape determining protein MreB Mrl
JZ786_11010	COG2814	Major facilitator Superfamily
JZ786_11020	COG0326	Molecular chaperone. Has ATPase activity
JZ786_11050	COG2205	protein histidine kinase activity
JZ786_11055	COG0745	RESPONSE REGULATOR receiver
JZ786_11080	COG0006	proline dipeptidase activity
JZ786_11095	COG1971	Probably functions as a manganese efflux pump
JZ786_11125	COG2199	diguanylate cyclase activity
JZ786_11125	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JZ786_11145	COG0674	pyruvate-flavodoxin oxidoreductase activity
JZ786_11160	COG0028	Belongs to the TPP enzyme family
JZ786_11165	COG3383	formate dehydrogenase (NAD+) activity
JZ786_11175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JZ786_11230	COG2211	Major facilitator Superfamily
JZ786_11235	COG0512	Glutamine amidotransferase of anthranilate synthase
JZ786_11265	COG2135	peptidase activity
JZ786_11280	COG1113	amino acid transport
JZ786_11285	COG1832	CoA-binding protein
JZ786_11295	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JZ786_11300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JZ786_11305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JZ786_11315	COG0069	glutamate synthase activity
JZ786_11315	COG0070	glutamate synthase
JZ786_11315	COG0067	glutamate synthase
JZ786_11325	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JZ786_11330	COG0137	argininosuccinate synthase activity
JZ786_11335	COG0165	Argininosuccinate lyase
JZ786_11355	COG0586	Pfam SNARE associated Golgi protein
JZ786_11360	COG3906	Belongs to the UPF0473 family
JZ786_11405	COG0740	serine-type endopeptidase activity
JZ786_11415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JZ786_11420	COG1104	cysteine desulfurase activity
JZ786_11425	COG0301	tRNA thio-modification
JZ786_11455	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_11460	COG0439	Biotin carboxylase
JZ786_11465	COG0511	ligase activity, forming carbon-carbon bonds
JZ786_11470	COG1024	Enoyl-CoA hydratase
JZ786_11475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JZ786_11480	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JZ786_11485	COG2001	Belongs to the MraZ family
JZ786_11490	COG0275	rRNA processing
JZ786_11500	COG0768	penicillin binding
JZ786_11505	COG0768	penicillin binding
JZ786_11510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JZ786_11515	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JZ786_11520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JZ786_11525	COG0772	Belongs to the SEDS family
JZ786_11535	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JZ786_11540	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JZ786_11555	COG3856	small basic protein
JZ786_11560	COG0849	cell division
JZ786_11565	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JZ786_11575	COG1191	sigma factor activity
JZ786_11580	COG1191	sigma factor activity
JZ786_11585	COG1873	PFAM PRC-barrel domain
JZ786_11590	COG1496	oxidoreductase activity
JZ786_11595	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JZ786_11605	COG2302	S4 RNA-binding domain
JZ786_11610	COG3599	regulation of cell shape
JZ786_11625	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JZ786_11630	COG0564	pseudouridine synthase activity
JZ786_11635	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JZ786_11645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JZ786_11660	COG0284	orotidine-5'-phosphate decarboxylase activity
JZ786_11665	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JZ786_11675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JZ786_11690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JZ786_11695	COG1561	YicC-like family, N-terminal region
JZ786_11700	COG2052	Domain of unknown function (DUF370)
JZ786_11705	COG0194	GDP metabolic process
JZ786_11710	COG1758	RNA polymerase activity
JZ786_11715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JZ786_11720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JZ786_11725	COG0242	peptide deformylase activity
JZ786_11730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JZ786_11735	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JZ786_11735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JZ786_11740	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JZ786_11745	COG0631	protein serine/threonine phosphatase activity
JZ786_11750	COG0515	serine threonine protein kinase
JZ786_11750	COG2815	serine threonine protein kinase
JZ786_11755	COG1162	GTPase activity
JZ786_11760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JZ786_11770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JZ786_11775	COG1302	Protein conserved in bacteria
JZ786_11780	COG1461	Dihydroxyacetone kinase
JZ786_11785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JZ786_11810	COG0154	amidase activity
JZ786_11820	COG0742	ribosomal rna small subunit methyltransferase
JZ786_11825	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JZ786_11830	COG1752	Esterase of the alpha-beta hydrolase superfamily
JZ786_11840	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JZ786_11850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JZ786_11855	COG1349	DNA-binding transcription factor activity
JZ786_11865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JZ786_11870	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JZ786_11875	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_11880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JZ786_11885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JZ786_11890	COG0571	ribonuclease III activity
JZ786_11895	COG1196	nuclear chromosome segregation
JZ786_11900	COG0552	protein localization to endoplasmic reticulum
JZ786_11905	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JZ786_11910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JZ786_11915	COG0228	four-way junction DNA binding
JZ786_11930	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JZ786_11935	COG0336	Belongs to the RNA methyltransferase TrmD family
JZ786_11970	COG0824	Thioesterase
JZ786_11980	COG0739	heme binding
JZ786_12005	COG1566	PFAM secretion protein HlyD family protein
JZ786_12010	COG0335	large ribosomal subunit rRNA binding
JZ786_12015	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JZ786_12030	COG2257	FlhB HrpN YscU SpaS Family
JZ786_12035	COG0792	nuclease activity
JZ786_12050	COG0045	succinate-CoA ligase (ADP-forming) activity
JZ786_12055	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JZ786_12065	COG0758	DNA mediated transformation
JZ786_12070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JZ786_12075	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JZ786_12080	COG4974	Belongs to the 'phage' integrase family
JZ786_12085	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JZ786_12090	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JZ786_12105	COG1677	Flagellar hook-basal body complex protein FliE
JZ786_12110	COG1766	The M ring may be actively involved in energy transduction
JZ786_12115	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JZ786_12125	COG1157	protein secretion by the type III secretion system
JZ786_12145	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JZ786_12165	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JZ786_12170	COG1776	CheC inhibitor of MCP methylation
JZ786_12170	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JZ786_12175	COG2201	protein-glutamate methylesterase activity
JZ786_12185	COG1338	Plays a role in the flagellum-specific transport system
JZ786_12190	COG1987	bacterial-type flagellum assembly
JZ786_12195	COG1684	flagellar biosynthetic protein fliR
JZ786_12200	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JZ786_12205	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JZ786_12210	COG1419	protein localization to endoplasmic reticulum
JZ786_12220	COG0835	chemotaxis
JZ786_12225	COG1776	CheC inhibitor of MCP methylation
JZ786_12230	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JZ786_12240	COG0052	Belongs to the universal ribosomal protein uS2 family
JZ786_12245	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JZ786_12250	COG0528	UMP kinase activity
JZ786_12255	COG0233	cytoplasmic translational termination
JZ786_12265	COG4589	Belongs to the CDS family
JZ786_12270	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JZ786_12275	COG0750	zinc metalloprotease
JZ786_12280	COG0442	prolyl-tRNA aminoacylation
JZ786_12285	COG2176	DNA-directed DNA polymerase activity
JZ786_12295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JZ786_12300	COG1215	transferase activity, transferring glycosyl groups
JZ786_12305	COG1217	gtp-binding protein TYPA
JZ786_12310	COG0779	Required for maturation of 30S ribosomal subunits
JZ786_12315	COG0195	Participates in both transcription termination and antitermination
JZ786_12320	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JZ786_12330	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JZ786_12335	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JZ786_12340	COG2404	hydrolase activity, acting on ester bonds
JZ786_12345	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JZ786_12350	COG0196	riboflavin kinase activity
JZ786_12355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JZ786_12360	COG1185	polyribonucleotide nucleotidyltransferase activity
JZ786_12365	COG0726	polysaccharide deacetylase
JZ786_12370	COG0612	Peptidase, M16
JZ786_12380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JZ786_12385	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JZ786_12390	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JZ786_12395	COG0527	aspartate kinase activity
JZ786_12400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JZ786_12405	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JZ786_12410	COG0740	serine-type endopeptidase activity
JZ786_12420	COG1674	ftsk spoiiie
JZ786_12445	COG1426	Protein conserved in bacteria
JZ786_12450	COG1666	GTP binding
JZ786_12455	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JZ786_12460	COG1058	Belongs to the CinA family
JZ786_12460	COG1546	Belongs to the CinA family
JZ786_12465	COG0513	Belongs to the DEAD box helicase family
JZ786_12470	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JZ786_12480	COG1418	mRNA catabolic process
JZ786_12485	COG1692	metallophosphoesterase
JZ786_12490	COG2359	stage V sporulation protein S
JZ786_12510	COG0189	ligase activity
JZ786_12520	COG0189	ligase activity
JZ786_12525	COG0384	phenazine biosynthesis protein PhzF
JZ786_12555	COG3250	beta-galactosidase activity
JZ786_12565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JZ786_12575	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JZ786_12580	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JZ786_12595	COG1923	regulation of RNA biosynthetic process
JZ786_12665	COG0697	spore germination
JZ786_12685	COG0489	protein tyrosine kinase activity
JZ786_12690	COG0438	transferase activity, transferring glycosyl groups
JZ786_12695	COG0438	transferase activity, transferring glycosyl groups
JZ786_12710	COG0438	transferase activity, transferring glycosyl groups
JZ786_12720	COG1216	Glycosyl transferase, family 2
JZ786_12740	COG0110	maltose O-acetyltransferase activity
JZ786_12760	COG4974	Belongs to the 'phage' integrase family
JZ786_12765	COG0517	IMP dehydrogenase activity
JZ786_12780	COG0110	maltose O-acetyltransferase activity
JZ786_12835	COG1132	(ABC) transporter
JZ786_12840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JZ786_12855	COG3459	Glycosyltransferase 36 associated
JZ786_12865	COG0464	growth
JZ786_12970	COG0697	spore germination
JZ786_12995	COG2199	diguanylate cyclase activity
JZ786_13015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JZ786_13020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JZ786_13050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JZ786_13055	COG0464	growth
JZ786_13075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JZ786_13080	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JZ786_13085	COG0789	Transcriptional regulator
JZ786_13090	COG0174	glutamine synthetase
JZ786_13095	COG0534	Mate efflux family protein
JZ786_13100	COG0667	Aldo Keto reductase
JZ786_13125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JZ786_13135	COG0561	phosphatase activity
JZ786_13140	COG0423	glycine-tRNA ligase activity
JZ786_13150	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_13170	COG1396	sequence-specific DNA binding
JZ786_13175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JZ786_13185	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JZ786_13190	COG0367	asparagine synthase
JZ786_13195	COG0438	transferase activity, transferring glycosyl groups
JZ786_13205	COG2814	Major facilitator Superfamily
JZ786_13210	COG1760	l-serine dehydratase
JZ786_13215	COG1760	l-serine dehydratase
JZ786_13220	COG0583	DNA-binding transcription factor activity
JZ786_13225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JZ786_13230	COG1012	belongs to the aldehyde dehydrogenase family
JZ786_13285	COG1053	succinate dehydrogenase
JZ786_13300	COG0477	Major facilitator Superfamily
JZ786_13305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JZ786_13310	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JZ786_13355	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JZ786_13380	COG3291	Pkd domain containing protein
JZ786_13380	COG3525	Glycosyl hydrolase, family 20, catalytic domain
JZ786_13385	COG0583	DNA-binding transcription factor activity
JZ786_13390	COG1380	Effector of murein hydrolase LrgA
JZ786_13395	COG1346	cytolysis
JZ786_13405	COG4990	cell redox homeostasis
JZ786_13410	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_13420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JZ786_13455	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JZ786_13460	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JZ786_13485	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JZ786_13490	COG1140	nitrate reductase beta subunit
JZ786_13500	COG2181	nitrate reductase activity
JZ786_13520	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JZ786_13525	COG1140	nitrate reductase beta subunit
JZ786_13535	COG2181	nitrate reductase activity
JZ786_13610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JZ786_13615	COG2721	sulfolactate sulfo-lyase activity
JZ786_13620	COG2721	sulfolactate sulfo-lyase activity
JZ786_13625	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JZ786_13630	COG2186	Transcriptional regulator
JZ786_13635	COG0531	amino acid
JZ786_13640	COG0028	Belongs to the TPP enzyme family
JZ786_13645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JZ786_13660	COG0494	nUDIX hydrolase
JZ786_13690	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JZ786_13715	COG3832	glyoxalase III activity
JZ786_13725	COG0346	lactoylglutathione lyase activity
JZ786_13775	COG1215	transferase activity, transferring glycosyl groups
JZ786_13795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JZ786_13800	COG0456	acetyltransferase
JZ786_13800	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JZ786_13825	COG0789	Transcriptional regulator
JZ786_13845	COG2318	DinB family
JZ786_13875	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JZ786_13880	COG2318	DinB family
JZ786_13915	COG3340	Belongs to the peptidase S51 family
JZ786_13970	COG4372	Transposase
JZ786_14055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JZ786_14070	COG5577	PFAM Coat F domain
JZ786_14075	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JZ786_14085	COG1295	ribonuclease BN
JZ786_14095	COG3935	DnaD domain protein
JZ786_14100	COG0017	Asparaginyl-tRNA synthetase
JZ786_14105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JZ786_14125	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JZ786_14135	COG0402	S-adenosylhomocysteine deaminase activity
JZ786_14140	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JZ786_14145	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JZ786_14150	COG1793	dna ligase
JZ786_14150	COG3285	dna ligase
JZ786_14155	COG1793	dna ligase
JZ786_14160	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JZ786_14165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JZ786_14165	COG1199	ATP-dependent helicase activity
JZ786_14175	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JZ786_14175	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JZ786_14180	COG0617	tRNA 3'-terminal CCA addition
JZ786_14185	COG0438	transferase activity, transferring glycosyl groups
JZ786_14190	COG1803	Methylglyoxal synthase
JZ786_14195	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JZ786_14205	COG1694	Mazg nucleotide pyrophosphohydrolase
JZ786_14210	COG3314	Sporulation integral membrane protein YlbJ
JZ786_14215	COG1968	undecaprenyl-diphosphatase activity
JZ786_14220	COG3949	Membrane
JZ786_14225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JZ786_14260	COG0287	Prephenate dehydrogenase
JZ786_14265	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JZ786_14280	COG0135	phosphoribosylanthranilate isomerase activity
JZ786_14285	COG0134	indole-3-glycerol-phosphate synthase activity
JZ786_14290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JZ786_14295	COG4401	Chorismate mutase type I
JZ786_14300	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JZ786_14305	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JZ786_14310	COG1363	Peptidase, m42
JZ786_14315	COG1363	Peptidase, m42
JZ786_14320	COG1363	Peptidase, m42
JZ786_14325	COG0564	pseudouridine synthase activity
JZ786_14335	COG1388	LysM domain
JZ786_14335	COG0791	NLP P60 protein
JZ786_14345	COG1970	mechanosensitive ion channel activity
JZ786_14350	COG0077	Prephenate dehydratase
JZ786_14355	COG1752	Esterase of the alpha-beta hydrolase superfamily
JZ786_14360	COG0105	UTP biosynthetic process
JZ786_14370	COG2226	methyltransferase
JZ786_14385	COG0776	regulation of translation
JZ786_14390	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JZ786_14395	COG0509	glycine decarboxylation via glycine cleavage system
JZ786_14400	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JZ786_14405	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JZ786_14410	COG1160	GTP binding
JZ786_14435	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JZ786_14465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JZ786_14470	COG4862	establishment of competence for transformation
JZ786_14475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JZ786_14480	COG1609	Transcriptional regulator
JZ786_14490	COG0210	DNA helicase
JZ786_14490	COG0210	DNA helicase
JZ786_14500	COG2226	methyltransferase
JZ786_14515	COG0508	dehydrogenase complex catalyzes the overall conversion of
JZ786_14520	COG0567	Dehydrogenase, E1 component
JZ786_14525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JZ786_14545	COG2339	peptidase activity
JZ786_14560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JZ786_14565	COG1476	TRANSCRIPTIONal
JZ786_14575	COG5002	protein histidine kinase activity
JZ786_14580	COG0745	RESPONSE REGULATOR receiver
JZ786_14585	COG1187	pseudouridine synthase activity
JZ786_14590	COG0700	Nucleoside recognition
JZ786_14595	COG2715	membrane protein required for spore maturation
JZ786_14600	COG3874	Sporulation protein YtfJ
JZ786_14610	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JZ786_14615	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JZ786_14620	COG1994	Peptidase M50
JZ786_14640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JZ786_14650	COG1191	sigma factor activity
JZ786_14655	COG2172	sigma factor antagonist activity
JZ786_14660	COG1366	Belongs to the anti-sigma-factor antagonist family
JZ786_14665	COG1686	Belongs to the peptidase S11 family
JZ786_14675	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JZ786_14680	COG4974	Belongs to the 'phage' integrase family
JZ786_14695	COG1300	Membrane
JZ786_14700	COG1379	DNA repair
JZ786_14710	COG2195	Cleaves the N-terminal amino acid of tripeptides
JZ786_14715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JZ786_14720	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JZ786_14720	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JZ786_14725	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JZ786_14725	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JZ786_14730	COG0321	lipoyl(octanoyl) transferase activity
JZ786_14735	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JZ786_14740	COG0508	dehydrogenase complex catalyzes the overall conversion of
JZ786_14745	COG0022	dehydrogenase e1 component
JZ786_14750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JZ786_14755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JZ786_14760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JZ786_14765	COG3829	transcription factor binding
JZ786_14765	COG3290	protein histidine kinase activity
JZ786_14775	COG0315	cyclic pyranopterin monophosphate synthase activity
JZ786_14785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JZ786_14790	COG3858	chitin binding
JZ786_14850	COG0697	spore germination
JZ786_14865	COG1279	arginine transmembrane transporter activity
JZ786_14870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JZ786_14875	COG0697	spore germination
JZ786_14905	COG0330	HflC and HflK could
JZ786_14910	COG1725	Transcriptional regulator
JZ786_14940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JZ786_14975	COG0697	spore germination
JZ786_14985	COG1595	DNA-templated transcription, initiation
JZ786_15005	COG2113	Glycine betaine
JZ786_15030	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JZ786_15065	COG2095	MarC family integral membrane protein
JZ786_15070	COG0586	Pfam SNARE associated Golgi protein
JZ786_15075	COG2205	protein histidine kinase activity
JZ786_15080	COG0425	Belongs to the sulfur carrier protein TusA family
JZ786_15085	COG2210	Belongs to the sulfur carrier protein TusA family
JZ786_15095	COG0446	pyridine nucleotide-disulphide oxidoreductase
JZ786_15105	COG0750	zinc metalloprotease
JZ786_15110	COG0497	DNA recombination
JZ786_15115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JZ786_15125	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JZ786_15130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JZ786_15145	COG1722	exodeoxyribonuclease VII activity
JZ786_15150	COG1570	exodeoxyribonuclease VII activity
JZ786_15155	COG0492	ferredoxin-NADP+ reductase activity
JZ786_15160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JZ786_15165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JZ786_15180	COG1302	Protein conserved in bacteria
JZ786_15185	COG0439	Biotin carboxylase
JZ786_15190	COG0511	ligase activity, forming carbon-carbon bonds
JZ786_15230	COG3854	ATPases associated with a variety of cellular activities
JZ786_15235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JZ786_15240	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JZ786_15250	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JZ786_15255	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JZ786_15260	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JZ786_15265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JZ786_15275	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JZ786_15280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JZ786_15305	COG2165	general secretion pathway protein
JZ786_15325	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JZ786_15335	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JZ786_15340	COG2868	ribosomal protein
JZ786_15345	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JZ786_15350	COG0517	IMP dehydrogenase activity
JZ786_15350	COG1994	Peptidase M50
JZ786_15360	COG2894	cell division
JZ786_15365	COG0850	regulation of cytokinetic process
JZ786_15380	COG1077	Cell shape determining protein MreB Mrl
JZ786_15400	COG3583	domain protein
JZ786_15400	COG3584	3D domain protein
JZ786_15405	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JZ786_15415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JZ786_15420	COG0285	dihydrofolate synthase activity
JZ786_15425	COG0525	valine-tRNA ligase activity
JZ786_15445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JZ786_15450	COG0113	porphobilinogen synthase activity
JZ786_15460	COG0181	hydroxymethylbilane synthase activity
JZ786_15465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JZ786_15480	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JZ786_15485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JZ786_15490	COG1067	ATP-dependent peptidase activity
JZ786_15490	COG0470	DNA polymerase III
JZ786_15495	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JZ786_15500	COG0740	serine-type endopeptidase activity
JZ786_15505	COG0544	peptidyl-prolyl cis-trans isomerase activity
JZ786_15530	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JZ786_15535	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JZ786_15540	COG1846	Transcriptional regulator
JZ786_15555	COG2197	response regulator
JZ786_15560	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JZ786_15570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JZ786_15575	COG1053	succinate dehydrogenase
JZ786_15580	COG2009	succinate dehydrogenase
JZ786_15585	COG0322	excinuclease ABC activity
JZ786_15610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JZ786_15620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JZ786_15630	COG0387	Pfam Sodium calcium exchanger
JZ786_15645	COG1316	TRANSCRIPTIONal
JZ786_15650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JZ786_15655	COG2084	Dehydrogenase
JZ786_15660	COG1846	Transcriptional regulator
JZ786_15665	COG1187	pseudouridine synthase activity
JZ786_15680	COG0655	NAD(P)H dehydrogenase (quinone) activity
JZ786_15690	COG3344	reverse transcriptase
JZ786_15700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JZ786_15705	COG0647	UMP catabolic process
JZ786_15710	COG2096	Adenosyltransferase
JZ786_15730	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JZ786_15750	COG0640	Transcriptional regulator
JZ786_15775	COG0735	belongs to the Fur family
JZ786_15790	COG0791	NLP P60 protein
JZ786_15790	COG1388	LysM domain
JZ786_15795	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JZ786_15800	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JZ786_15825	COG0714	Associated with various cellular activities
JZ786_15830	COG3263	regulation of cellular component size
JZ786_15840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JZ786_15850	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JZ786_15860	COG0318	PFAM AMP-dependent synthetase and ligase
JZ786_15865	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JZ786_15870	COG1575	Belongs to the MenA family. Type 1 subfamily
JZ786_15875	COG1331	Highly conserved protein containing a thioredoxin domain
JZ786_15885	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_15890	COG1024	Enoyl-CoA hydratase
JZ786_15900	COG1960	acyl-CoA dehydrogenase activity
JZ786_15905	COG0318	PFAM AMP-dependent synthetase and ligase
JZ786_15915	COG2197	response regulator
JZ786_15935	COG0697	spore germination
JZ786_15970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JZ786_15975	COG0517	IMP dehydrogenase activity
JZ786_15980	COG1132	(ABC) transporter
JZ786_15985	COG1132	(ABC) transporter
JZ786_15990	COG0542	response to heat
JZ786_16010	COG0454	-acetyltransferase
JZ786_16015	COG2226	methyltransferase
JZ786_16040	COG1285	pathogenesis
JZ786_16050	COG2318	DinB family
JZ786_16055	COG2814	Major facilitator Superfamily
JZ786_16060	COG2843	Capsule synthesis protein
JZ786_16065	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JZ786_16070	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JZ786_16075	COG1827	regulation of RNA biosynthetic process
JZ786_16110	COG0395	ABC-type sugar transport system, permease component
JZ786_16115	COG1175	transmembrane transport
JZ786_16120	COG2205	protein histidine kinase activity
JZ786_16125	COG0745	RESPONSE REGULATOR receiver
JZ786_16130	COG0561	phosphatase activity
JZ786_16140	COG1175	transmembrane transport
JZ786_16175	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JZ786_16180	COG2201	protein-glutamate methylesterase activity
JZ786_16185	COG1051	belongs to the nudix hydrolase family
JZ786_16190	COG3344	reverse transcriptase
JZ786_16200	COG0730	response to heat
JZ786_16210	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JZ786_16230	COG3858	chitin binding
JZ786_16245	COG4191	Histidine kinase
JZ786_16265	COG1033	growth of symbiont in host cell
JZ786_16265	COG2409	Drug exporters of the RND superfamily
JZ786_16270	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JZ786_16275	COG0833	amino acid
JZ786_16280	COG0463	Glycosyl transferase, family 2
JZ786_16300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JZ786_16320	COG1595	DNA-templated transcription, initiation
JZ786_16330	COG1657	PFAM Prenyltransferase squalene oxidase
JZ786_16350	COG0534	Mate efflux family protein
JZ786_16355	COG1971	Probably functions as a manganese efflux pump
JZ786_16365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JZ786_16370	COG5002	protein histidine kinase activity
JZ786_16375	COG0745	RESPONSE REGULATOR receiver
JZ786_16385	COG1937	Protein conserved in bacteria
JZ786_16390	COG2217	Heavy metal translocating P-type atpase
JZ786_16395	COG4454	pyrroloquinoline quinone binding
JZ786_16405	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JZ786_16410	COG2384	SAM-dependent methyltransferase
JZ786_16420	COG1960	acyl-CoA dehydrogenase activity
JZ786_16425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JZ786_16430	COG0358	DNA primase activity
JZ786_16435	COG0574	Belongs to the PEP-utilizing enzyme family
JZ786_16435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JZ786_16440	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JZ786_16445	COG0517	IMP dehydrogenase activity
JZ786_16450	COG1381	Involved in DNA repair and RecF pathway recombination
JZ786_16460	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JZ786_16465	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JZ786_16470	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JZ786_16475	COG1480	7TM receptor with intracellular HD hydrolase
JZ786_16480	COG1702	phosphate starvation-inducible protein PhoH
JZ786_16495	COG1610	YqeY-like protein
JZ786_16500	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JZ786_16505	COG1283	sodium-dependent phosphate transmembrane transporter activity
JZ786_16510	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JZ786_16515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JZ786_16520	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JZ786_16525	COG2264	protein methyltransferase activity
JZ786_16535	COG0443	Heat shock 70 kDa protein
JZ786_16545	COG1420	regulation of RNA biosynthetic process
JZ786_16550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JZ786_16555	COG0481	GTPase activity
JZ786_16570	COG0741	lytic transglycosylase activity
JZ786_16575	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JZ786_16580	COG0268	Binds directly to 16S ribosomal RNA
JZ786_16590	COG1252	NADH dehydrogenase
JZ786_16605	COG1596	polysaccharide export
JZ786_16605	COG1555	photosystem II stabilization
JZ786_16610	COG1321	iron dependent repressor
JZ786_16615	COG2226	methyltransferase
JZ786_16620	COG0799	negative regulation of ribosome biogenesis
JZ786_16625	COG1713	HD superfamily hydrolase involved in NAD metabolism
JZ786_16630	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JZ786_16635	COG1534	Rna-binding protein
JZ786_16640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JZ786_16655	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JZ786_16665	COG0768	penicillin binding
JZ786_16675	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JZ786_16680	COG4472	Bacterial protein of unknown function (DUF965)
JZ786_16695	COG0628	permease
JZ786_16700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JZ786_16705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JZ786_16715	COG1104	cysteine desulfurase activity
JZ786_16720	COG1959	2 iron, 2 sulfur cluster binding
JZ786_16740	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JZ786_16755	COG1921	L-seryl-tRNASec selenium transferase activity
JZ786_16760	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JZ786_16780	COG1566	PFAM secretion protein HlyD family protein
JZ786_16790	COG1131	(ABC) transporter
JZ786_16800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JZ786_16830	COG1960	acyl-CoA dehydrogenase activity
JZ786_16840	COG1960	acyl-CoA dehydrogenase activity
JZ786_16855	COG0004	ammonium transporteR
JZ786_16885	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JZ786_16890	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JZ786_16895	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JZ786_16895	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JZ786_16900	COG0183	Belongs to the thiolase family
JZ786_16920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JZ786_16925	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_16930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JZ786_16930	COG0596	Alpha beta hydrolase
JZ786_16930	COG2226	methyltransferase
JZ786_16940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JZ786_16950	COG0303	'Molybdopterin
JZ786_16965	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JZ786_16985	COG0318	PFAM AMP-dependent synthetase and ligase
JZ786_16990	COG1960	acyl-CoA dehydrogenase activity
JZ786_17000	COG1074	ATP-dependent DNA helicase activity
JZ786_17005	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JZ786_17010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JZ786_17020	COG2814	Major facilitator Superfamily
JZ786_17025	COG1686	Belongs to the peptidase S11 family
JZ786_17035	COG0179	Fumarylacetoacetate (FAA) hydrolase
JZ786_17045	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JZ786_17065	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JZ786_17070	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JZ786_17075	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JZ786_17080	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JZ786_17085	COG0569	domain protein
JZ786_17090	COG1388	LysM domain
JZ786_17090	COG3942	CHAP domain
JZ786_17100	COG3344	reverse transcriptase
JZ786_17105	COG2271	Major facilitator Superfamily
JZ786_17120	COG0735	belongs to the Fur family
JZ786_17140	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JZ786_17165	COG0840	transmembrane signaling receptor activity
JZ786_17185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JZ786_17190	COG1490	D-aminoacyl-tRNA deacylase activity
JZ786_17195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JZ786_17200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JZ786_17205	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JZ786_17205	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JZ786_17210	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JZ786_17215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JZ786_17220	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JZ786_17230	COG2244	polysaccharide biosynthetic process
JZ786_17235	COG2323	membrane
JZ786_17250	COG1862	Preprotein translocase
JZ786_17255	COG0343	queuine tRNA-ribosyltransferase activity
JZ786_17260	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JZ786_17265	COG4447	cellulose binding
JZ786_17270	COG1191	sigma factor activity
JZ786_17275	COG2255	four-way junction helicase activity
JZ786_17280	COG0632	four-way junction helicase activity
JZ786_17285	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JZ786_17295	COG0217	transcriptional regulatory protein
JZ786_17325	COG1193	negative regulation of DNA recombination
JZ786_17340	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JZ786_17345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JZ786_17345	COG0072	phenylalanine-tRNA ligase activity
JZ786_17350	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JZ786_17370	COG5002	protein histidine kinase activity
JZ786_17375	COG0704	Plays a role in the regulation of phosphate uptake
JZ786_17380	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JZ786_17385	COG1968	undecaprenyl-diphosphatase activity
JZ786_17395	COG0569	domain protein
JZ786_17400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JZ786_17405	COG0318	PFAM AMP-dependent synthetase and ligase
JZ786_17420	COG4585	Histidine kinase
JZ786_17435	COG0644	oxidoreductase
JZ786_17440	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JZ786_17485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JZ786_17495	COG5002	protein histidine kinase activity
JZ786_17510	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JZ786_17515	COG1294	oxidase, subunit
JZ786_17520	COG1271	oxidase subunit
JZ786_17530	COG2814	Major facilitator Superfamily
JZ786_17545	COG0179	Fumarylacetoacetate (FAA) hydrolase
JZ786_17555	COG1054	Belongs to the UPF0176 family
JZ786_17570	COG1742	UPF0060 membrane protein
JZ786_17635	COG0109	protoheme IX farnesyltransferase activity
JZ786_17640	COG0768	penicillin binding
JZ786_17645	COG3546	catalase activity
JZ786_17670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JZ786_17675	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JZ786_17680	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JZ786_17685	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JZ786_17690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JZ786_17715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JZ786_17725	COG1131	(ABC) transporter
JZ786_17740	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JZ786_17745	COG3088	subunit of a heme lyase
JZ786_17745	COG4235	cytochrome complex assembly
JZ786_17770	COG1294	oxidase, subunit
JZ786_17775	COG1271	oxidase subunit
JZ786_17780	COG4585	Histidine kinase
JZ786_17785	COG2197	response regulator
JZ786_17790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JZ786_17790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JZ786_17810	COG1113	amino acid transport
JZ786_17825	COG0367	asparagine synthase
JZ786_17850	COG1022	Amp-dependent synthetase and ligase
JZ786_17860	COG2176	DNA-directed DNA polymerase activity
JZ786_17865	COG0243	molybdopterin cofactor binding
JZ786_17875	COG0437	4 iron, 4 sulfur cluster binding
JZ786_17880	COG0583	DNA-binding transcription factor activity
JZ786_17905	COG0425	Belongs to the sulfur carrier protein TusA family
JZ786_17905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JZ786_17910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JZ786_17910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JZ786_17920	COG0768	penicillin binding
JZ786_17925	COG1612	heme a metabolic process
JZ786_17950	COG4974	Belongs to the 'phage' integrase family
JZ786_17995	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JZ786_18000	COG0705	Rhomboid family
JZ786_18000	COG0457	Tetratricopeptide repeat
JZ786_18015	COG0501	Belongs to the peptidase M48B family
JZ786_18020	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JZ786_18035	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JZ786_18055	COG0577	efflux transmembrane transporter activity
JZ786_18060	COG1136	(ABC) transporter
JZ786_18075	COG0517	IMP dehydrogenase activity
JZ786_18090	COG0372	Belongs to the citrate synthase family
JZ786_18095	COG2197	response regulator
JZ786_18100	COG4585	Histidine kinase
JZ786_18115	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JZ786_18120	COG1809	phosphosulfolactate synthase activity
JZ786_18130	COG0285	dihydrofolate synthase activity
JZ786_18135	COG0024	Methionine aminopeptidase
JZ786_18150	COG0154	amidase activity
JZ786_18170	COG1012	belongs to the aldehyde dehydrogenase family
JZ786_18175	COG0586	Pfam SNARE associated Golgi protein
JZ786_18195	COG4555	ABC transporter
JZ786_18205	COG0179	Fumarylacetoacetate (FAA) hydrolase
JZ786_18240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JZ786_18255	COG0785	Cytochrome C biogenesis protein
JZ786_18260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JZ786_18265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JZ786_18275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JZ786_18280	COG0598	Magnesium transport protein CorA
JZ786_18290	COG1940	carbohydrate kinase activity
JZ786_18300	COG1388	LysM domain
JZ786_18300	COG3858	chitin binding
JZ786_18315	COG0400	carboxylic ester hydrolase activity
JZ786_18320	COG0346	lactoylglutathione lyase activity
JZ786_18325	COG0589	response to stress
JZ786_18330	COG2814	Major facilitator Superfamily
JZ786_18340	COG3858	chitin binding
JZ786_18340	COG1388	LysM domain
JZ786_18365	COG0714	Associated with various cellular activities
JZ786_18395	COG1132	(ABC) transporter
JZ786_18400	COG1132	(ABC) transporter
JZ786_18405	COG0166	Belongs to the GPI family
JZ786_18415	COG2155	Conserved Protein
JZ786_18425	COG2233	PERMEase
JZ786_18435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JZ786_18440	COG0601	transmembrane transport
JZ786_18445	COG0747	negative chemotaxis
JZ786_18450	COG4608	Belongs to the ABC transporter superfamily
JZ786_18455	COG0444	Belongs to the ABC transporter superfamily
JZ786_18465	COG0095	Lipoate-protein ligase
JZ786_18475	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JZ786_18480	COG0583	DNA-binding transcription factor activity
JZ786_18490	COG0697	spore germination
JZ786_18500	COG1609	Transcriptional regulator
JZ786_18505	COG1070	Carbohydrate kinase
JZ786_18510	COG2271	Major facilitator Superfamily
JZ786_18515	COG1132	(ABC) transporter
JZ786_18520	COG1132	(ABC) transporter
JZ786_18530	COG1181	Belongs to the D-alanine--D-alanine ligase family
JZ786_18535	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JZ786_18550	COG1067	ATP-dependent peptidase activity
JZ786_18560	COG2151	metal-sulfur cluster biosynthetic enzyme
JZ786_18595	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JZ786_18635	COG2267	carboxylic ester hydrolase activity
JZ786_18640	COG2318	DinB family
JZ786_18650	COG5002	protein histidine kinase activity
JZ786_18665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JZ786_18680	COG2814	Major facilitator Superfamily
JZ786_18690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JZ786_18705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JZ786_18705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JZ786_18740	COG2814	Major facilitator Superfamily
JZ786_18775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JZ786_18785	COG1082	Xylose isomerase domain protein TIM barrel
JZ786_18790	COG0346	lactoylglutathione lyase activity
JZ786_18800	COG3619	membrane
JZ786_18810	COG0352	thiamine-phosphate diphosphorylase activity
JZ786_18815	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JZ786_18830	COG5002	protein histidine kinase activity
JZ786_18835	COG5002	protein histidine kinase activity
JZ786_18840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JZ786_18855	COG1510	regulation of RNA biosynthetic process
JZ786_18860	COG2076	Multidrug Resistance protein
JZ786_18865	COG1175	transmembrane transport
JZ786_18870	COG0395	ABC-type sugar transport system, permease component
JZ786_18880	COG2814	Major facilitator Superfamily
JZ786_18885	COG1492	cobalamin metabolic process
JZ786_18935	COG0438	transferase activity, transferring glycosyl groups
JZ786_18940	COG0488	(ABC) transporter
JZ786_18945	COG4895	conserved protein (DUF2196)
JZ786_18960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JZ786_18970	COG0667	Aldo Keto reductase
JZ786_18980	COG2814	Major facilitator Superfamily
JZ786_18985	COG2188	Transcriptional regulator
JZ786_19010	COG0726	polysaccharide deacetylase
JZ786_19030	COG2217	Heavy metal translocating P-type atpase
JZ786_19055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JZ786_19085	COG2814	Major facilitator Superfamily
JZ786_19095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JZ786_19100	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JZ786_19115	COG1012	belongs to the aldehyde dehydrogenase family
JZ786_19140	COG0028	Belongs to the TPP enzyme family
JZ786_19150	COG1414	Transcriptional regulator
JZ786_19155	COG0395	ABC-type sugar transport system, permease component
JZ786_19160	COG1175	transmembrane transport
JZ786_19175	COG1609	Transcriptional regulator
JZ786_19180	COG2199	diguanylate cyclase activity
JZ786_19180	COG2200	EAL domain
JZ786_19190	COG1501	Belongs to the glycosyl hydrolase 31 family
JZ786_19205	COG1472	Belongs to the glycosyl hydrolase 3 family
JZ786_19230	COG1609	Transcriptional regulator
JZ786_19235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JZ786_19245	COG1064	alcohol dehydrogenase
JZ786_19250	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_19270	COG1846	Transcriptional regulator
JZ786_19275	COG0477	Major facilitator Superfamily
JZ786_19285	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_19290	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JZ786_19295	COG1960	acyl-CoA dehydrogenase activity
JZ786_19300	COG0318	PFAM AMP-dependent synthetase and ligase
JZ786_19320	COG1960	acyl-CoA dehydrogenase activity
JZ786_19330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JZ786_19350	COG0531	amino acid
JZ786_19360	COG3852	Histidine kinase
JZ786_19380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JZ786_19390	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JZ786_19445	COG1263	PTS System
JZ786_19445	COG2190	(PTS) system
JZ786_19445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JZ786_19450	COG3250	beta-galactosidase activity
JZ786_19460	COG0800	Aldolase
JZ786_19465	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_19470	COG1312	Catalyzes the dehydration of D-mannonate
JZ786_19480	COG1609	Transcriptional regulator
JZ786_19490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JZ786_19495	COG2860	membrane
JZ786_19500	COG0697	spore germination
JZ786_19515	COG2267	carboxylic ester hydrolase activity
JZ786_19520	COG0288	reversible hydration of carbon dioxide
JZ786_19525	COG5609	conserved protein (DUF2294)
JZ786_19530	COG3002	Belongs to the UPF0753 family
JZ786_19535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JZ786_19550	COG0477	Major facilitator Superfamily
JZ786_19560	COG0617	tRNA 3'-terminal CCA addition
JZ786_19560	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JZ786_19560	COG3620	sequence-specific DNA binding
JZ786_19575	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JZ786_19580	COG0697	spore germination
JZ786_19585	COG2002	toxin-antitoxin pair type II binding
JZ786_19600	COG1376	ErfK ybiS ycfS ynhG family protein
JZ786_19625	COG0463	Glycosyl transferase, family 2
JZ786_19625	COG0457	Tetratricopeptide repeat
JZ786_19630	COG0438	transferase activity, transferring glycosyl groups
JZ786_19655	COG1252	NADH dehydrogenase
JZ786_19670	COG1960	acyl-CoA dehydrogenase activity
JZ786_19675	COG1960	acyl-CoA dehydrogenase activity
JZ786_19690	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JZ786_19705	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JZ786_19715	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JZ786_19725	COG1960	acyl-CoA dehydrogenase activity
JZ786_19730	COG2096	Adenosyltransferase
JZ786_19740	COG2079	MmgE PrpD family protein
JZ786_19750	COG4608	Belongs to the ABC transporter superfamily
JZ786_19765	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JZ786_19770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JZ786_19785	COG0322	excinuclease ABC activity
JZ786_19805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JZ786_19845	COG0109	protoheme IX farnesyltransferase activity
JZ786_19905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JZ786_19910	COG1309	transcriptional regulator
JZ786_19930	COG2814	Major facilitator Superfamily
JZ786_19935	COG2860	membrane
JZ786_19950	COG3383	formate dehydrogenase (NAD+) activity
JZ786_19965	COG1271	oxidase subunit
JZ786_19970	COG4221	oxidoreductase activity
JZ786_19980	COG4221	oxidoreductase activity
JZ786_19985	COG0655	NAD(P)H dehydrogenase (quinone) activity
JZ786_20000	COG0693	protein deglycase activity
JZ786_20010	COG1733	regulation of RNA biosynthetic process
JZ786_20015	COG0697	spore germination
JZ786_20020	COG0640	Transcriptional regulator
JZ786_20025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JZ786_20030	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JZ786_20040	COG1802	Transcriptional regulator
JZ786_20055	COG3344	reverse transcriptase
JZ786_20125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JZ786_20170	COG2318	DinB family
JZ786_20215	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JZ786_20215	COG0456	acetyltransferase
JZ786_20225	COG0697	spore germination
JZ786_20250	COG1309	transcriptional regulator
JZ786_20265	COG1595	DNA-templated transcription, initiation
JZ786_20325	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JZ786_20335	COG0741	lytic transglycosylase activity
JZ786_20340	COG0237	dephospho-CoA kinase activity
JZ786_20345	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JZ786_20350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JZ786_20350	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JZ786_20360	COG0538	isocitrate dehydrogenase activity
JZ786_20365	COG0180	Tryptophanyl-tRNA synthetase
JZ786_20375	COG0277	FAD linked oxidase domain protein
JZ786_20395	COG3344	reverse transcriptase
JZ786_20405	COG0205	6-phosphofructokinase activity
JZ786_20410	COG0825	malonyl-CoA metabolic process
JZ786_20415	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JZ786_20425	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JZ786_20430	COG0587	DNA-directed DNA polymerase activity
JZ786_20435	COG4109	DRTGG domain
JZ786_20440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JZ786_20465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JZ786_20470	COG1473	amidohydrolase
JZ786_20475	COG1396	sequence-specific DNA binding
JZ786_20490	COG1438	arginine binding
JZ786_20500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JZ786_20510	COG0765	amino acid transport
JZ786_20515	COG1126	abc transporter atp-binding protein
JZ786_20520	COG0765	amino acid transport
JZ786_20535	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JZ786_20550	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JZ786_20555	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JZ786_20575	COG0398	Pfam SNARE associated Golgi protein
JZ786_20580	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JZ786_20585	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JZ786_20585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JZ786_20595	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JZ786_20595	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JZ786_20600	COG1045	serine acetyltransferase
JZ786_20605	COG1914	H( )-stimulated, divalent metal cation uptake system
JZ786_20625	COG0569	domain protein
JZ786_20625	COG0475	glutathione-regulated potassium exporter activity
JZ786_20630	COG4496	protein, YerC YecD
JZ786_20655	COG1250	3-hydroxyacyl-CoA dehydrogenase
JZ786_20660	COG1024	Enoyl-CoA hydratase
JZ786_20675	COG0785	Cytochrome C biogenesis protein
JZ786_20680	COG2113	Glycine betaine
JZ786_20685	COG4176	ABC-type proline glycine betaine transport system permease component
JZ786_20695	COG2130	NADP-dependent
JZ786_20705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JZ786_20710	COG1072	(Pantothenic acid kinase))
JZ786_20720	COG0393	Putative heavy-metal-binding
JZ786_20725	COG1090	epimerase
JZ786_20740	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_20755	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_20770	COG2309	aminopeptidase activity
JZ786_20775	COG2095	MarC family integral membrane protein
JZ786_20790	COG3973	AAA domain
JZ786_20795	COG0477	Major facilitator Superfamily
JZ786_20800	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JZ786_20825	COG0109	protoheme IX farnesyltransferase activity
JZ786_20840	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JZ786_20845	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JZ786_20865	COG0535	radical SAM domain protein
JZ786_20875	COG1671	Belongs to the UPF0178 family
JZ786_20880	COG1376	ErfK ybiS ycfS ynhG family protein
JZ786_20900	COG2046	Belongs to the sulfate adenylyltransferase family
JZ786_20905	COG0529	Catalyzes the synthesis of activated sulfate
JZ786_20915	COG2205	protein histidine kinase activity
JZ786_20920	COG0745	RESPONSE REGULATOR receiver
JZ786_20940	COG2223	nitrite transmembrane transporter activity
JZ786_20945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JZ786_20985	COG1227	inorganic diphosphatase activity
JZ786_20995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JZ786_21005	COG0667	Aldo Keto reductase
JZ786_21010	COG1506	peptidase
JZ786_21010	COG0823	Involved in the tonB-independent uptake of proteins
JZ786_21010	COG4946	Tricorn protease homolog
JZ786_21020	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_21040	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_21045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JZ786_21075	COG1113	amino acid transport
JZ786_21085	COG3706	GGDEF domain
JZ786_21125	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JZ786_21130	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JZ786_21135	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JZ786_21150	COG0745	RESPONSE REGULATOR receiver
JZ786_21155	COG1902	pentaerythritol trinitrate reductase activity
JZ786_21160	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JZ786_21165	COG1845	cytochrome c oxidase, subunit III
JZ786_21180	COG0730	response to heat
JZ786_21195	COG2814	Major facilitator Superfamily
JZ786_21235	COG2814	Major facilitator Superfamily
JZ786_21240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JZ786_21245	COG3842	ATPase activity
JZ786_21295	COG2814	Major facilitator Superfamily
JZ786_21305	COG2814	Major facilitator Superfamily
JZ786_21310	COG0366	Alpha amylase catalytic
JZ786_21380	COG1304	FMN binding
JZ786_21385	COG1612	heme a metabolic process
JZ786_21395	COG2986	histidine ammonia-lyase
JZ786_21400	COG0010	Belongs to the arginase family
JZ786_21405	COG1228	amidohydrolase
JZ786_21415	COG2207	Transcriptional regulator
JZ786_21430	COG1506	peptidase
JZ786_21465	COG0151	Belongs to the GarS family
JZ786_21470	COG0138	bifunctional purine biosynthesis protein purh
JZ786_21475	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JZ786_21480	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JZ786_21485	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JZ786_21490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JZ786_21505	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JZ786_21510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JZ786_21515	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JZ786_21520	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JZ786_21525	COG2252	PERMEase
JZ786_21530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JZ786_21530	COG0519	Catalyzes the synthesis of GMP from XMP
JZ786_21540	COG1305	Transglutaminase-like
JZ786_21550	COG0714	Associated with various cellular activities
JZ786_21555	COG0459	protein refolding
JZ786_21565	COG0805	protein transport
JZ786_21570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JZ786_21595	COG0671	phosphoesterase, PA-phosphatase related
JZ786_21600	COG0488	(ABC) transporter
JZ786_21605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JZ786_21610	COG3829	transcription factor binding
JZ786_21620	COG0366	Alpha amylase catalytic
JZ786_21625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JZ786_21635	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JZ786_21640	COG0456	acetyltransferase
JZ786_21650	COG0802	atpase or kinase
JZ786_21655	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JZ786_21660	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JZ786_21700	COG2337	Toxic component of a toxin-antitoxin (TA) module
JZ786_21705	COG0864	Transcriptional regulator
JZ786_21710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JZ786_21715	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JZ786_21720	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JZ786_21720	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JZ786_21725	COG0736	holo-[acyl-carrier-protein] synthase activity
JZ786_21745	COG3844	kynureninase activity
JZ786_21765	COG3189	MarR family transcriptional regulator
JZ786_21770	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JZ786_21785	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JZ786_21790	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JZ786_21795	COG0572	uridine kinase
JZ786_21805	COG0768	penicillin binding
JZ786_21835	COG4464	protein tyrosine phosphatase activity
JZ786_21845	COG1335	isochorismatase
JZ786_21850	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
JZ786_21850	COG0662	Cupin 2, conserved barrel domain protein
JZ786_21865	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JZ786_21880	COG1482	cell wall glycoprotein biosynthetic process
JZ786_21885	COG2201	protein-glutamate methylesterase activity
JZ786_21890	COG0835	chemotaxis
JZ786_21895	COG2198	Histidine kinase
JZ786_21895	COG0643	Histidine kinase
JZ786_21910	COG0745	RESPONSE REGULATOR receiver
JZ786_21915	COG2205	protein histidine kinase activity
JZ786_21920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JZ786_21925	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JZ786_21940	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JZ786_21945	COG4988	ABC transporter
JZ786_21950	COG1294	oxidase, subunit
JZ786_21955	COG1271	oxidase subunit
JZ786_21985	COG0363	glucosamine-6-phosphate deaminase activity
JZ786_21995	COG2971	BadF BadG BcrA BcrD
JZ786_22000	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JZ786_22005	COG3876	Protein conserved in bacteria
JZ786_22010	COG1737	Transcriptional regulator
JZ786_22015	COG2814	Major facilitator Superfamily
JZ786_22020	COG4989	oxidoreductase activity
JZ786_22040	COG0579	oxidoreductase
JZ786_22050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JZ786_22065	COG1741	Belongs to the pirin family
JZ786_22085	COG2720	vancomycin resistance protein
JZ786_22090	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_22110	COG0318	PFAM AMP-dependent synthetase and ligase
JZ786_22115	COG2814	Major facilitator Superfamily
JZ786_22125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JZ786_22145	COG0277	FAD linked oxidase domain protein
JZ786_22155	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JZ786_22160	COG3012	SEC-C Motif Domain Protein
JZ786_22170	COG0318	PFAM AMP-dependent synthetase and ligase
JZ786_22175	COG0318	PFAM AMP-dependent synthetase and ligase
JZ786_22185	COG0768	penicillin binding
JZ786_22190	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JZ786_22195	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JZ786_22200	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JZ786_22205	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JZ786_22210	COG1473	amidohydrolase
JZ786_22215	COG0747	negative chemotaxis
JZ786_22220	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JZ786_22225	COG2814	Major facilitator Superfamily
JZ786_22230	COG4499	WXG100 protein secretion system (Wss), protein YukC
JZ786_22230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JZ786_22235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JZ786_22245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JZ786_22250	COG0022	dehydrogenase e1 component
JZ786_22255	COG0508	dehydrogenase complex catalyzes the overall conversion of
JZ786_22260	COG0494	nUDIX hydrolase
JZ786_22270	COG0747	negative chemotaxis
JZ786_22275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JZ786_22280	COG0601	transmembrane transport
JZ786_22285	COG0673	inositol 2-dehydrogenase activity
JZ786_22295	COG0673	inositol 2-dehydrogenase activity
JZ786_22305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JZ786_22310	COG0604	alcohol dehydrogenase
JZ786_22315	COG4585	Histidine kinase
JZ786_22320	COG2197	response regulator
JZ786_22335	COG3336	cytochrome c oxidase
JZ786_22355	COG3718	enzyme involved in inositol metabolism
JZ786_22360	COG0246	Mannitol dehydrogenase
JZ786_22365	COG2721	sulfolactate sulfo-lyase activity
JZ786_22370	COG0800	Aldolase
JZ786_22380	COG1609	Transcriptional regulator
JZ786_22385	COG1063	alcohol dehydrogenase
JZ786_22390	COG5577	PFAM Coat F domain
JZ786_22410	COG3191	aminopeptidase activity
JZ786_22425	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JZ786_22435	COG3383	formate dehydrogenase (NAD+) activity
JZ786_22440	COG1733	regulation of RNA biosynthetic process
JZ786_22450	COG1733	regulation of RNA biosynthetic process
JZ786_22455	COG0196	riboflavin kinase activity
JZ786_22460	COG4499	WXG100 protein secretion system (Wss), protein YukC
JZ786_22460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JZ786_22465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JZ786_22480	COG2017	converts alpha-aldose to the beta-anomer
JZ786_22485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JZ786_22490	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JZ786_22500	COG1349	DNA-binding transcription factor activity
JZ786_22505	COG0531	amino acid
JZ786_22525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JZ786_22530	COG1929	Belongs to the glycerate kinase type-1 family
JZ786_22540	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JZ786_22545	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JZ786_22570	COG0653	protein targeting
JZ786_22575	COG0791	NLP P60 protein
JZ786_22585	COG1316	TRANSCRIPTIONal
JZ786_22600	COG0667	Aldo Keto reductase
JZ786_22605	COG1228	amidohydrolase
JZ786_22610	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JZ786_22625	COG2205	protein histidine kinase activity
JZ786_22630	COG2205	protein histidine kinase activity
JZ786_22640	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JZ786_22645	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JZ786_22650	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JZ786_22665	COG0745	RESPONSE REGULATOR receiver
JZ786_22675	COG0463	Glycosyl transferase, family 2
JZ786_22690	COG0596	Alpha beta hydrolase
JZ786_22690	COG2226	methyltransferase
JZ786_22690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JZ786_22695	COG0277	FAD linked oxidase domain protein
JZ786_22730	COG3344	reverse transcriptase
JZ786_22740	COG5002	protein histidine kinase activity
JZ786_22760	COG0589	response to stress
JZ786_22775	COG0477	Major facilitator Superfamily
JZ786_22810	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JZ786_22815	COG3858	chitin binding
JZ786_22815	COG1388	LysM domain
JZ786_22825	COG0395	ABC-type sugar transport system, permease component
JZ786_22830	COG1175	transmembrane transport
JZ786_22835	COG1653	transport
JZ786_22840	COG0316	Belongs to the HesB IscA family
JZ786_22865	COG0527	aspartate kinase activity
JZ786_22905	COG0697	spore germination
JZ786_22910	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JZ786_22920	COG2271	Major facilitator Superfamily
JZ786_22940	COG0651	ATP synthesis coupled electron transport
JZ786_22955	COG3260	NADH ubiquinone oxidoreductase 20
JZ786_22970	COG0651	ATP synthesis coupled electron transport
JZ786_22985	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JZ786_23000	COG2201	protein-glutamate methylesterase activity
JZ786_23035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JZ786_23050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JZ786_23055	COG0601	transmembrane transport
JZ786_23060	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JZ786_23070	COG2271	Major facilitator Superfamily
JZ786_23080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JZ786_23105	COG0444	Belongs to the ABC transporter superfamily
JZ786_23110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JZ786_23115	COG0601	transmembrane transport
JZ786_23125	COG1609	Transcriptional regulator
JZ786_23145	COG2814	Major facilitator Superfamily
JZ786_23150	COG2814	Major facilitator Superfamily
JZ786_23155	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JZ786_23180	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JZ786_23185	COG1414	Transcriptional regulator
JZ786_23190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JZ786_23200	COG0251	oxidation-reduction process
JZ786_23210	COG4454	pyrroloquinoline quinone binding
JZ786_23215	COG1388	LysM domain
JZ786_23215	COG0791	NLP P60 protein
JZ786_23220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JZ786_23230	COG0681	Belongs to the peptidase S26 family
JZ786_23240	COG0667	Aldo Keto reductase
JZ786_23250	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JZ786_23255	COG3706	GGDEF domain
JZ786_23270	COG0154	amidase activity
JZ786_23275	COG2031	fatty acid transporter
JZ786_23280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JZ786_23300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JZ786_23320	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JZ786_23325	COG0583	DNA-binding transcription factor activity
JZ786_23330	COG2079	MmgE PrpD family protein
JZ786_23335	COG2271	Major facilitator Superfamily
JZ786_23340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JZ786_23345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JZ786_23350	COG1024	Enoyl-CoA hydratase
JZ786_23370	COG0428	transporter
JZ786_23375	COG4499	WXG100 protein secretion system (Wss), protein YukC
JZ786_23375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JZ786_23390	COG0681	Belongs to the peptidase S26 family
JZ786_23400	COG2197	response regulator
JZ786_23405	COG4585	Histidine kinase
JZ786_23410	COG1012	belongs to the aldehyde dehydrogenase family
JZ786_23415	COG2205	protein histidine kinase activity
JZ786_23425	COG3852	Histidine kinase
JZ786_23440	COG0737	Belongs to the 5'-nucleotidase family
JZ786_23465	COG0737	Belongs to the 5'-nucleotidase family
JZ786_23475	COG4632	Exopolysaccharide biosynthesis protein
JZ786_23475	COG5434	Belongs to the glycosyl hydrolase 28 family
JZ786_23490	COG1069	ribulokinase activity
JZ786_23500	COG1172	Belongs to the binding-protein-dependent transport system permease family
JZ786_23505	COG1129	ABC transporter
JZ786_23510	COG1879	ABC-type sugar transport system periplasmic component
JZ786_23520	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_23540	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JZ786_23550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JZ786_23575	COG1609	Transcriptional regulator
JZ786_23580	COG2030	dehydratase
JZ786_23585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JZ786_23600	COG0531	amino acid
JZ786_23615	COG1476	TRANSCRIPTIONal
JZ786_23625	COG0640	Transcriptional regulator
JZ786_23675	COG1595	DNA-templated transcription, initiation
JZ786_23685	COG5504	Zn-dependent protease
JZ786_23695	COG1028	Short-chain dehydrogenase reductase Sdr
JZ786_23795	COG3654	unkown
JZ786_23815	COG2814	Major facilitator Superfamily
JZ786_23845	COG3012	SEC-C Motif Domain Protein
JZ786_23855	COG0641	radical SAM
JZ786_23860	COG2814	Major facilitator Superfamily
JZ786_23880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JZ786_23885	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JZ786_23885	COG2755	lipolytic protein G-D-S-L family
JZ786_23890	COG0772	Belongs to the SEDS family
JZ786_23900	COG2814	Major facilitator Superfamily
JZ786_23910	COG0641	radical SAM
JZ786_23915	COG3119	arylsulfatase activity
JZ786_23920	COG3119	arylsulfatase activity
JZ786_23925	COG1940	carbohydrate kinase activity
JZ786_23925	COG1846	Transcriptional regulator
JZ786_23930	COG3119	arylsulfatase activity
JZ786_23940	COG2814	Major facilitator Superfamily
JZ786_23945	COG3119	arylsulfatase activity
JZ786_23950	COG0277	FAD linked oxidase domain protein
JZ786_23955	COG3250	beta-galactosidase activity
JZ786_23980	COG1953	Uracil, thiamine, allantoin
JZ786_23990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JZ786_24000	COG1414	Transcriptional regulator
JZ786_24015	COG1874	Beta-galactosidase
JZ786_24020	COG3833	ABC-type maltose transport systems, permease component
JZ786_24025	COG1175	transmembrane transport
JZ786_24040	COG1609	Transcriptional regulator
JZ786_24045	COG3867	Arabinogalactan endo-beta-1,4-galactanase
JZ786_24050	COG3622	Belongs to the hyi family
JZ786_24065	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JZ786_24070	COG4715	Zinc finger, swim domain protein
JZ786_24090	COG0668	transmembrane transport
JZ786_24095	COG0598	Magnesium transport protein CorA
JZ786_24100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JZ786_24125	COG0643	Histidine kinase
JZ786_24125	COG2198	Histidine kinase
JZ786_24130	COG0835	chemotaxis
JZ786_24140	COG0835	chemotaxis
JZ786_24145	COG0840	transmembrane signaling receptor activity
JZ786_24150	COG2201	protein-glutamate methylesterase activity
JZ786_24160	COG0531	amino acid
JZ786_24165	COG1757	Na H antiporter
JZ786_24170	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JZ786_24190	COG0531	amino acid
JZ786_24195	COG2204	response regulator
JZ786_24200	COG1012	belongs to the aldehyde dehydrogenase family
JZ786_24205	COG0506	proline dehydrogenase activity
JZ786_24210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JZ786_24215	COG1053	succinate dehydrogenase
JZ786_24245	COG2201	protein-glutamate methylesterase activity
JZ786_24250	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JZ786_24255	COG2198	Histidine kinase
JZ786_24255	COG0643	Histidine kinase
JZ786_24260	COG0835	chemotaxis
JZ786_24270	COG0835	chemotaxis
JZ786_24275	COG0840	transmembrane signaling receptor activity
JZ786_24280	COG2201	protein-glutamate methylesterase activity
JZ786_24295	COG0789	Transcriptional regulator
JZ786_24305	COG2771	luxR family
JZ786_24305	COG2200	EAL domain
JZ786_24320	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JZ786_24320	COG2755	lipolytic protein G-D-S-L family
JZ786_24415	COG4974	Belongs to the 'phage' integrase family
JZ786_24425	COG1609	Transcriptional regulator
JZ786_24435	COG3119	arylsulfatase activity
JZ786_24435	COG3408	Glycogen debranching enzyme
JZ786_24440	COG2814	Major facilitator Superfamily
JZ786_24460	COG1492	cobalamin metabolic process
JZ786_24465	COG2003	Belongs to the UPF0758 family
JZ786_24640	COG0551	DNA topoisomerase type I activity
JZ786_24640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JZ786_24695	COG1192	Involved in chromosome partitioning