locus-tag	class	description
GI364_00010	COG0592	DNA-directed DNA polymerase activity
GI364_00015	COG2501	S4 domain
GI364_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GI364_00030	COG0187	DNA topoisomerase II activity
GI364_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GI364_00040	COG0589	response to stress
GI364_00070	COG0517	IMP dehydrogenase activity
GI364_00070	COG0516	GMP reductase activity
GI364_00075	COG1686	Belongs to the peptidase S11 family
GI364_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GI364_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GI364_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GI364_00115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI364_00145	COG1725	Transcriptional regulator
GI364_00155	COG1131	(ABC) transporter
GI364_00195	COG3842	ATPase activity
GI364_00200	COG1653	transport
GI364_00210	COG0395	ABC-type sugar transport system, permease component
GI364_00220	COG3708	Transcriptional regulator
GI364_00220	COG2207	Transcriptional regulator
GI364_00245	COG3842	ATPase activity
GI364_00250	COG4208	sulfate ABC transporter
GI364_00265	COG0840	transmembrane signaling receptor activity
GI364_00285	COG1131	(ABC) transporter
GI364_00300	COG0006	proline dipeptidase activity
GI364_00315	COG0393	Putative heavy-metal-binding
GI364_00320	COG0393	Putative heavy-metal-binding
GI364_00325	COG1842	Phage shock protein A
GI364_00340	COG0488	(ABC) transporter
GI364_00345	COG1234	tRNA 3'-trailer cleavage
GI364_00350	COG0561	phosphatase activity
GI364_00365	COG3842	ATPase activity
GI364_00385	COG3328	transposase activity
GI364_00390	COG3383	formate dehydrogenase (NAD+) activity
GI364_00395	COG2427	Protein of unknown function (DUF1641)
GI364_00415	COG1595	DNA-templated transcription, initiation
GI364_00425	COG2508	Transcriptional regulator
GI364_00430	COG0006	proline dipeptidase activity
GI364_00440	COG1473	amidohydrolase
GI364_00445	COG0460	homoserine dehydrogenase
GI364_00450	COG1012	belongs to the aldehyde dehydrogenase family
GI364_00455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GI364_00460	COG2423	ornithine cyclodeaminase activity
GI364_00470	COG0765	amino acid transport
GI364_00475	COG1126	abc transporter atp-binding protein
GI364_00480	COG0765	amino acid transport
GI364_00490	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GI364_00520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GI364_00520	COG4499	WXG100 protein secretion system (Wss), protein YukC
GI364_00525	COG0768	penicillin binding
GI364_00530	COG0463	Glycosyl transferase, family 2
GI364_00540	COG5002	protein histidine kinase activity
GI364_00545	COG2814	Major facilitator Superfamily
GI364_00560	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GI364_00565	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_00595	COG3069	C4-dicarboxylate transmembrane transporter activity
GI364_00600	COG0463	Glycosyl transferase, family 2
GI364_00605	COG2246	polysaccharide biosynthetic process
GI364_00620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GI364_00630	COG1682	transport, permease protein
GI364_00675	COG0427	acetyl-CoA hydrolase
GI364_00680	COG0506	proline dehydrogenase activity
GI364_00690	COG1012	belongs to the aldehyde dehydrogenase family
GI364_00720	COG0667	Aldo Keto reductase
GI364_00725	COG1595	DNA-templated transcription, initiation
GI364_00735	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_00740	COG1960	acyl-CoA dehydrogenase activity
GI364_00750	COG0789	Transcriptional regulator
GI364_00755	COG3279	Response regulator of the LytR AlgR family
GI364_00760	COG0427	acetyl-CoA hydrolase
GI364_00790	COG1131	(ABC) transporter
GI364_00800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GI364_00815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GI364_00825	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GI364_00840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GI364_00850	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_00855	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_00865	COG5002	protein histidine kinase activity
GI364_00870	COG0745	RESPONSE REGULATOR receiver
GI364_00885	COG2271	Major facilitator Superfamily
GI364_00900	COG1027	Aspartate ammonia-lyase
GI364_00910	COG1929	Belongs to the glycerate kinase type-1 family
GI364_00915	COG0531	amino acid
GI364_00930	COG2267	carboxylic ester hydrolase activity
GI364_00950	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GI364_00965	COG0564	pseudouridine synthase activity
GI364_00980	COG4585	Histidine kinase
GI364_00985	COG2197	response regulator
GI364_01020	COG0456	acetyltransferase
GI364_01040	COG0655	NAD(P)H dehydrogenase (quinone) activity
GI364_01065	COG1309	transcriptional regulator
GI364_01075	COG0840	transmembrane signaling receptor activity
GI364_01085	COG0444	Belongs to the ABC transporter superfamily
GI364_01090	COG4608	Belongs to the ABC transporter superfamily
GI364_01100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_01105	COG0601	transmembrane transport
GI364_01120	COG0395	ABC-type sugar transport system, permease component
GI364_01125	COG1175	transmembrane transport
GI364_01135	COG0768	penicillin binding
GI364_01145	COG0514	ATP-dependent DNA helicase (RecQ)
GI364_01150	COG0673	inositol 2-dehydrogenase activity
GI364_01165	COG0747	negative chemotaxis
GI364_01180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GI364_01190	COG1960	acyl-CoA dehydrogenase activity
GI364_01200	COG1476	TRANSCRIPTIONal
GI364_01235	COG4715	Zinc finger, swim domain protein
GI364_01250	COG2249	NAD(P)H dehydrogenase (quinone) activity
GI364_01255	COG0527	aspartate kinase activity
GI364_01260	COG4492	Belongs to the UPF0735 family
GI364_01265	COG0527	aspartate kinase activity
GI364_01275	COG3876	Protein conserved in bacteria
GI364_01285	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GI364_01290	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GI364_01295	COG2971	BadF BadG BcrA BcrD
GI364_01305	COG4948	Mandelate Racemase Muconate Lactonizing
GI364_01310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GI364_01320	COG4166	transmembrane transport
GI364_01330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_01335	COG0444	Belongs to the ABC transporter superfamily
GI364_01340	COG4608	Belongs to the ABC transporter superfamily
GI364_01345	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GI364_01355	COG1472	Belongs to the glycosyl hydrolase 3 family
GI364_01365	COG0154	amidase activity
GI364_01385	COG1091	dTDP-4-dehydrorhamnose reductase activity
GI364_01400	COG0529	Catalyzes the synthesis of activated sulfate
GI364_01405	COG0471	metal ion transport
GI364_01405	COG3273	potassium ion transport
GI364_01410	COG2046	Belongs to the sulfate adenylyltransferase family
GI364_01440	COG1215	transferase activity, transferring glycosyl groups
GI364_01460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GI364_01470	COG0582	viral genome integration into host DNA
GI364_01495	COG2318	DinB family
GI364_01505	COG2378	regulation of single-species biofilm formation
GI364_01510	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_01525	COG1442	glycosyl transferase family 8
GI364_01525	COG1216	Glycosyl transferase, family 2
GI364_01530	COG1316	TRANSCRIPTIONal
GI364_01570	COG1940	carbohydrate kinase activity
GI364_01580	COG0745	RESPONSE REGULATOR receiver
GI364_01585	COG2205	protein histidine kinase activity
GI364_01590	COG1131	(ABC) transporter
GI364_01605	COG0706	membrane insertase activity
GI364_01635	COG0583	DNA-binding transcription factor activity
GI364_01645	COG2814	Major facilitator Superfamily
GI364_01655	COG1940	carbohydrate kinase activity
GI364_01665	COG1175	transmembrane transport
GI364_01670	COG0395	ABC-type sugar transport system, permease component
GI364_01675	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GI364_01685	COG0363	glucosamine-6-phosphate deaminase activity
GI364_01720	COG2200	EAL domain
GI364_01720	COG2199	diguanylate cyclase activity
GI364_01725	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI364_01750	COG1132	(ABC) transporter
GI364_01765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GI364_01800	COG2201	protein-glutamate methylesterase activity
GI364_01805	COG0643	Histidine kinase
GI364_01805	COG2198	Histidine kinase
GI364_01820	COG2188	Transcriptional regulator
GI364_01840	COG0010	Belongs to the arginase family
GI364_01845	COG1228	amidohydrolase
GI364_01855	COG2207	Transcriptional regulator
GI364_01860	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GI364_01865	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GI364_01880	COG1131	(ABC) transporter
GI364_01885	COG2755	lipolytic protein G-D-S-L family
GI364_01885	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GI364_01895	COG1510	regulation of RNA biosynthetic process
GI364_01900	COG2113	Glycine betaine
GI364_01910	COG3191	aminopeptidase activity
GI364_01925	COG1177	transmembrane transport
GI364_01930	COG1840	ABC-type Fe3 transport system, periplasmic component
GI364_01935	COG3842	ATPase activity
GI364_01940	COG0583	DNA-binding transcription factor activity
GI364_01945	COG2814	Major facilitator Superfamily
GI364_01950	COG0791	NLP P60 protein
GI364_01950	COG1388	LysM domain
GI364_01955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GI364_01960	COG0765	amino acid transport
GI364_01965	COG1126	abc transporter atp-binding protein
GI364_01985	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GI364_01990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GI364_01990	COG3153	acetyltransferase
GI364_01995	COG1012	belongs to the aldehyde dehydrogenase family
GI364_02000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GI364_02005	COG1012	belongs to the aldehyde dehydrogenase family
GI364_02020	COG1917	Cupin 2, conserved barrel domain protein
GI364_02025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GI364_02030	COG0456	acetyltransferase
GI364_02045	COG4990	cell redox homeostasis
GI364_02050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GI364_02055	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GI364_02095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GI364_02110	COG0662	Cupin 2, conserved barrel domain protein
GI364_02110	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GI364_02120	COG5002	protein histidine kinase activity
GI364_02140	COG3547	Transposase (IS116 IS110 IS902 family)
GI364_02150	COG0823	Involved in the tonB-independent uptake of proteins
GI364_02150	COG1506	peptidase
GI364_02150	COG4946	Tricorn protease homolog
GI364_02160	COG2210	Belongs to the sulfur carrier protein TusA family
GI364_02165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_02170	COG0730	response to heat
GI364_02175	COG1309	transcriptional regulator
GI364_02180	COG1960	acyl-CoA dehydrogenase activity
GI364_02185	COG0439	Biotin carboxylase
GI364_02190	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GI364_02195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GI364_02200	COG0277	FAD linked oxidase domain protein
GI364_02220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_02235	COG1346	cytolysis
GI364_02240	COG1380	Effector of murein hydrolase LrgA
GI364_02245	COG0302	gtp cyclohydrolase
GI364_02250	COG0697	spore germination
GI364_02260	COG1511	domain protein
GI364_02265	COG1122	ATPase activity
GI364_02275	COG1802	Transcriptional regulator
GI364_02290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_02300	COG2059	Chromate
GI364_02305	COG2059	Chromate
GI364_02310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GI364_02320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GI364_02320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GI364_02345	COG0583	DNA-binding transcription factor activity
GI364_02350	COG0038	chloride channel
GI364_02355	COG1615	UPF0182 protein
GI364_02365	COG0367	asparagine synthase
GI364_02390	COG3852	Histidine kinase
GI364_02395	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GI364_02400	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GI364_02405	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GI364_02420	COG2244	polysaccharide biosynthetic process
GI364_02440	COG1982	Orn Lys Arg decarboxylase major
GI364_02445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GI364_02450	COG3870	Protein conserved in bacteria
GI364_02460	COG1774	PSP1 C-terminal conserved region
GI364_02465	COG4467	Involved in initiation control of chromosome replication
GI364_02470	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GI364_02475	COG2002	toxin-antitoxin pair type II binding
GI364_02485	COG0084	hydrolase, TatD family'
GI364_02490	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GI364_02495	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GI364_02500	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GI364_02515	COG4466	Protein conserved in bacteria
GI364_02525	COG4242	Belongs to the peptidase S51 family
GI364_02530	COG0189	ligase activity
GI364_02530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GI364_02535	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GI364_02540	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GI364_02545	COG0251	oxidation-reduction process
GI364_02550	COG2088	sporulation resulting in formation of a cellular spore
GI364_02555	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GI364_02560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GI364_02565	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GI364_02570	COG0193	aminoacyl-tRNA hydrolase activity
GI364_02580	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GI364_02590	COG2002	toxin-antitoxin pair type II binding
GI364_02595	COG2244	polysaccharide biosynthetic process
GI364_02600	COG3956	TIGRFAM MazG family protein
GI364_02610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GI364_02630	COG1098	S1 RNA binding domain
GI364_02650	COG0717	Belongs to the dCTP deaminase family
GI364_02655	COG2208	phosphoserine phosphatase activity
GI364_02660	COG2304	oxidoreductase activity
GI364_02665	COG0515	serine threonine protein kinase
GI364_02670	COG0037	tRNA processing
GI364_02680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GI364_02690	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GI364_02695	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GI364_02700	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GI364_02705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GI364_02710	COG1396	sequence-specific DNA binding
GI364_02715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GI364_02720	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GI364_02750	COG1653	transport
GI364_02765	COG0366	Alpha amylase catalytic
GI364_02770	COG4948	Mandelate Racemase Muconate Lactonizing
GI364_02805	COG2197	response regulator
GI364_02850	COG2884	Cell division ATP-binding protein ftsE
GI364_02855	COG2177	Part of the ABC transporter FtsEX involved in
GI364_02860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI364_02865	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GI364_02870	COG1360	Flagellar Motor Protein
GI364_02875	COG0556	nucleotide-excision repair
GI364_02880	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GI364_02885	COG2508	Transcriptional regulator
GI364_02890	COG3842	ATPase activity
GI364_02895	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GI364_02905	COG0018	arginyl-trna synthetase
GI364_02920	COG1051	belongs to the nudix hydrolase family
GI364_02925	COG1940	carbohydrate kinase activity
GI364_02930	COG1660	Displays ATPase and GTPase activities
GI364_02935	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GI364_02940	COG1481	regulation of sporulation
GI364_02945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GI364_02955	COG2197	response regulator
GI364_02960	COG4585	Histidine kinase
GI364_02965	COG0842	Transport permease protein
GI364_02970	COG0842	Transport permease protein
GI364_02975	COG1131	(ABC) transporter
GI364_02990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_02995	COG1194	a g-specific adenine glycosylase
GI364_03000	COG0670	Belongs to the BI1 family
GI364_03005	COG0495	leucyl-tRNA aminoacylation
GI364_03020	COG2211	Major facilitator Superfamily
GI364_03045	COG1205	dead DEAH box helicase
GI364_03045	COG1111	helicase
GI364_03050	COG3359	exonuclease
GI364_03060	COG3385	transposase activity
GI364_03065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GI364_03070	COG4493	Belongs to the UPF0637 family
GI364_03080	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_03090	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GI364_03105	COG0697	spore germination
GI364_03120	COG1396	sequence-specific DNA binding
GI364_03265	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GI364_03265	COG2105	PFAM AIG2 family protein
GI364_03285	COG1988	membrane-bound metal-dependent
GI364_03330	COG2226	methyltransferase
GI364_03355	COG2894	cell division
GI364_03405	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
GI364_03435	COG2199	diguanylate cyclase activity
GI364_03435	COG2202	Pas domain
GI364_03435	COG2200	EAL domain
GI364_03465	COG3706	GGDEF domain
GI364_03475	COG4251	negative regulation of phosphorylation
GI364_03475	COG2203	Gaf domain
GI364_03475	COG3706	GGDEF domain
GI364_03475	COG5001	Diguanylate cyclase
GI364_03495	COG0534	Mate efflux family protein
GI364_03505	COG3706	GGDEF domain
GI364_03505	COG2203	Gaf domain
GI364_03505	COG5001	Diguanylate cyclase
GI364_03505	COG4251	negative regulation of phosphorylation
GI364_03550	COG0697	spore germination
GI364_03575	COG4974	Belongs to the 'phage' integrase family
GI364_03605	COG0531	amino acid
GI364_03610	COG0582	viral genome integration into host DNA
GI364_03630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI364_03645	COG0697	spore germination
GI364_03660	COG0328	RNA-DNA hybrid ribonuclease activity
GI364_03665	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GI364_03670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GI364_03680	COG0473	3-isopropylmalate dehydrogenase activity
GI364_03690	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GI364_03695	COG0546	phosphoglycolate phosphatase activity
GI364_03710	COG0508	dehydrogenase complex catalyzes the overall conversion of
GI364_03730	COG2766	serine protein kinase
GI364_03740	COG0730	response to heat
GI364_03745	COG0730	response to heat
GI364_03765	COG2718	Belongs to the UPF0229 family
GI364_03775	COG1113	amino acid transport
GI364_03780	COG3033	Beta-eliminating lyase
GI364_03820	COG1396	sequence-specific DNA binding
GI364_03970	COG2105	PFAM AIG2 family protein
GI364_03985	COG0697	spore germination
GI364_04025	COG1988	membrane-bound metal-dependent
GI364_04070	COG1653	transport
GI364_04090	COG1797	cobyrinic acid a,c-diamide synthase activity
GI364_04095	COG1492	cobalamin metabolic process
GI364_04105	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GI364_04110	COG0406	alpha-ribazole phosphatase activity
GI364_04120	COG2096	Adenosyltransferase
GI364_04130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GI364_04135	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
GI364_04140	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GI364_04145	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GI364_04155	COG0406	alpha-ribazole phosphatase activity
GI364_04160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GI364_04175	COG0697	spore germination
GI364_04215	COG2894	cell division
GI364_04265	COG3300	MHYT domain
GI364_04265	COG5001	Diguanylate cyclase
GI364_04305	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
GI364_04335	COG2200	EAL domain
GI364_04370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GI364_04375	COG0372	Belongs to the citrate synthase family
GI364_04380	COG1921	L-seryl-tRNASec selenium transferase activity
GI364_04385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GI364_04400	COG2814	Major facilitator Superfamily
GI364_04425	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GI364_04435	COG2718	Belongs to the UPF0229 family
GI364_04440	COG2719	SpoVR family
GI364_04450	COG1595	DNA-templated transcription, initiation
GI364_04500	COG1595	DNA-templated transcription, initiation
GI364_04515	COG0840	transmembrane signaling receptor activity
GI364_04535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GI364_04540	COG2329	Antibiotic biosynthesis monooxygenase
GI364_04555	COG1309	transcriptional regulator
GI364_04565	COG0702	epimerase
GI364_04580	COG3835	regulator
GI364_04585	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GI364_04590	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GI364_04595	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GI364_04600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GI364_04610	COG0765	amino acid transport
GI364_04620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GI364_04625	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GI364_04630	COG1012	belongs to the aldehyde dehydrogenase family
GI364_04655	COG0601	transmembrane transport
GI364_04660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_04680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GI364_04695	COG0022	dehydrogenase e1 component
GI364_04715	COG0179	Fumarylacetoacetate (FAA) hydrolase
GI364_04720	COG1802	Transcriptional regulator
GI364_04730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GI364_04735	COG1012	belongs to the aldehyde dehydrogenase family
GI364_04750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GI364_04760	COG2814	Major facilitator Superfamily
GI364_04770	COG2169	Transcriptional regulator
GI364_04780	COG0640	Transcriptional regulator
GI364_04790	COG0129	dihydroxy-acid dehydratase activity
GI364_04795	COG0252	asparaginase activity
GI364_04800	COG2226	methyltransferase
GI364_04810	COG5002	protein histidine kinase activity
GI364_04815	COG0745	RESPONSE REGULATOR receiver
GI364_04825	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GI364_04835	COG0768	penicillin binding
GI364_04840	COG0076	glutamate decarboxylase activity
GI364_04860	COG4286	Uncharacterised protein family (UPF0160)
GI364_04865	COG2226	methyltransferase
GI364_04875	COG2076	Multidrug Resistance protein
GI364_04880	COG1175	transmembrane transport
GI364_04895	COG1067	ATP-dependent peptidase activity
GI364_04905	COG0095	Lipoate-protein ligase
GI364_04910	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GI364_04920	COG2814	Major facilitator Superfamily
GI364_04935	COG4585	Histidine kinase
GI364_04950	COG0561	phosphatase activity
GI364_04980	COG0004	ammonium transporteR
GI364_04990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GI364_05005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_05010	COG1309	transcriptional regulator
GI364_05015	COG1131	(ABC) transporter
GI364_05025	COG4895	conserved protein (DUF2196)
GI364_05030	COG0488	(ABC) transporter
GI364_05035	COG0450	alkyl hydroperoxide reductase
GI364_05045	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_05050	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GI364_05060	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_05070	COG0446	pyridine nucleotide-disulphide oxidoreductase
GI364_05070	COG1902	pentaerythritol trinitrate reductase activity
GI364_05080	COG2814	Major facilitator Superfamily
GI364_05085	COG2364	Membrane
GI364_05090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GI364_05125	COG0367	asparagine synthase
GI364_05130	COG0626	cystathionine gamma-synthase activity
GI364_05135	COG0840	transmembrane signaling receptor activity
GI364_05140	COG1725	Transcriptional regulator
GI364_05145	COG1131	(ABC) transporter
GI364_05160	COG5002	protein histidine kinase activity
GI364_05175	COG2197	response regulator
GI364_05185	COG2223	nitrite transmembrane transporter activity
GI364_05210	COG1304	FMN binding
GI364_05215	COG2814	Major facilitator Superfamily
GI364_05220	COG3773	Cell wall hydrolase
GI364_05220	COG3409	Peptidoglycan-binding domain 1 protein
GI364_05225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_05230	COG0492	ferredoxin-NADP+ reductase activity
GI364_05235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_05235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_05250	COG3336	cytochrome c oxidase
GI364_05280	COG4221	oxidoreductase activity
GI364_05285	COG0488	(ABC) transporter
GI364_05300	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_05315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GI364_05330	COG3385	transposase activity
GI364_05335	COG0584	glycerophosphoryl diester phosphodiesterase
GI364_05340	COG1970	mechanosensitive ion channel activity
GI364_05345	COG0069	glutamate synthase activity
GI364_05350	COG0584	glycerophosphoryl diester phosphodiesterase
GI364_05360	COG2199	diguanylate cyclase activity
GI364_05360	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GI364_05365	COG0667	Aldo Keto reductase
GI364_05370	COG0477	Major facilitator Superfamily
GI364_05375	COG2814	Major facilitator Superfamily
GI364_05400	COG1175	transmembrane transport
GI364_05405	COG0395	ABC-type sugar transport system, permease component
GI364_05420	COG0725	ABC transporter, periplasmic molybdate-binding protein
GI364_05430	COG3842	ATPase activity
GI364_05455	COG0768	penicillin binding
GI364_05465	COG2226	methyltransferase
GI364_05480	COG5002	protein histidine kinase activity
GI364_05485	COG0745	RESPONSE REGULATOR receiver
GI364_05495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GI364_05500	COG0667	Aldo Keto reductase
GI364_05510	COG1733	regulation of RNA biosynthetic process
GI364_05520	COG0463	Glycosyl transferase, family 2
GI364_05525	COG0456	acetyltransferase
GI364_05530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GI364_05535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GI364_05540	COG1120	ATPase activity
GI364_05555	COG2211	Major facilitator Superfamily
GI364_05565	COG0393	Putative heavy-metal-binding
GI364_05580	COG0697	spore germination
GI364_05585	COG0814	amino acid
GI364_05615	COG2135	peptidase activity
GI364_05625	COG0288	reversible hydration of carbon dioxide
GI364_05630	COG2205	protein histidine kinase activity
GI364_05635	COG2172	sigma factor antagonist activity
GI364_05655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GI364_05670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GI364_05675	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GI364_05680	COG0154	amidase activity
GI364_05685	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GI364_05690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GI364_05695	COG5002	protein histidine kinase activity
GI364_05700	COG0019	diaminopimelate decarboxylase activity
GI364_05740	COG1164	Oligoendopeptidase f
GI364_05750	COG3852	Histidine kinase
GI364_05755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GI364_05760	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GI364_05775	COG0126	phosphoglycerate kinase activity
GI364_05780	COG0149	triose-phosphate isomerase activity
GI364_05790	COG0148	phosphopyruvate hydratase activity
GI364_05795	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GI364_05805	COG0557	exoribonuclease II activity
GI364_05835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI364_05900	COG2207	Transcriptional regulator
GI364_05905	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_05920	COG1595	DNA-templated transcription, initiation
GI364_05940	COG0346	lactoylglutathione lyase activity
GI364_05945	COG2315	Protein conserved in bacteria
GI364_05950	COG1802	Transcriptional regulator
GI364_05955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GI364_05960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GI364_05965	COG1335	isochorismatase
GI364_05990	COG0514	ATP-dependent DNA helicase (RecQ)
GI364_05995	COG0789	Transcriptional regulator
GI364_06015	COG2197	response regulator
GI364_06020	COG4585	Histidine kinase
GI364_06030	COG2814	Major facilitator Superfamily
GI364_06035	COG0640	Transcriptional regulator
GI364_06040	COG0592	DNA-directed DNA polymerase activity
GI364_06045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GI364_06060	COG3848	Pyruvate phosphate dikinase
GI364_06060	COG0574	Belongs to the PEP-utilizing enzyme family
GI364_06065	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GI364_06070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GI364_06100	COG0745	RESPONSE REGULATOR receiver
GI364_06105	COG5002	protein histidine kinase activity
GI364_06110	COG1175	transmembrane transport
GI364_06115	COG0395	ABC-type sugar transport system, permease component
GI364_06125	COG3858	chitin binding
GI364_06125	COG1388	LysM domain
GI364_06135	COG0583	DNA-binding transcription factor activity
GI364_06145	COG2259	Doxx family
GI364_06150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GI364_06195	COG0730	response to heat
GI364_06220	COG0281	malic enzyme
GI364_06225	COG4989	oxidoreductase activity
GI364_06230	COG2318	DinB family
GI364_06235	COG2378	regulation of single-species biofilm formation
GI364_06250	COG3706	GGDEF domain
GI364_06260	COG0326	Molecular chaperone. Has ATPase activity
GI364_06270	COG2766	serine protein kinase
GI364_06275	COG2718	Belongs to the UPF0229 family
GI364_06280	COG2719	SpoVR family
GI364_06285	COG4221	oxidoreductase activity
GI364_06290	COG2201	protein-glutamate methylesterase activity
GI364_06300	COG4191	Histidine kinase
GI364_06305	COG0840	transmembrane signaling receptor activity
GI364_06305	COG3290	protein histidine kinase activity
GI364_06310	COG5001	Diguanylate cyclase
GI364_06310	COG3300	MHYT domain
GI364_06335	COG2205	protein histidine kinase activity
GI364_06340	COG0745	RESPONSE REGULATOR receiver
GI364_06350	COG1216	Glycosyl transferase, family 2
GI364_06355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_06360	COG0561	phosphatase activity
GI364_06365	COG3239	Fatty acid desaturase
GI364_06370	COG0386	Belongs to the glutathione peroxidase family
GI364_06385	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GI364_06405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GI364_06410	COG1116	anion transmembrane transporter activity
GI364_06415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GI364_06425	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GI364_06430	COG0667	Aldo Keto reductase
GI364_06440	COG1013	pyruvate-flavodoxin oxidoreductase activity
GI364_06445	COG0674	pyruvate-flavodoxin oxidoreductase activity
GI364_06445	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GI364_06450	COG2814	Major facilitator Superfamily
GI364_06455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GI364_06465	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GI364_06480	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GI364_06505	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GI364_06655	COG2153	protein acetylation
GI364_06690	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GI364_06695	COG1140	nitrate reductase beta subunit
GI364_06705	COG2181	nitrate reductase activity
GI364_06745	COG1744	ABC transporter substrate-binding protein PnrA-like
GI364_06750	COG3845	ABC transporter
GI364_06755	COG4603	Belongs to the binding-protein-dependent transport system permease family
GI364_06760	COG1079	Belongs to the binding-protein-dependent transport system permease family
GI364_06765	COG4294	response to UV
GI364_06770	COG3300	MHYT domain
GI364_06770	COG5001	Diguanylate cyclase
GI364_06775	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GI364_06800	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GI364_06810	COG3973	AAA domain
GI364_06825	COG1053	succinate dehydrogenase
GI364_06830	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GI364_06845	COG1489	DNA binding
GI364_06850	COG0006	proline dipeptidase activity
GI364_06860	COG0542	response to heat
GI364_06870	COG1937	Protein conserved in bacteria
GI364_06880	COG2323	membrane
GI364_06895	COG0475	glutathione-regulated potassium exporter activity
GI364_06895	COG0569	domain protein
GI364_06925	COG0154	amidase activity
GI364_06950	COG0596	Alpha beta hydrolase
GI364_06975	COG1131	(ABC) transporter
GI364_06990	COG0601	transmembrane transport
GI364_06995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_07000	COG0444	Belongs to the ABC transporter superfamily
GI364_07005	COG4608	Belongs to the ABC transporter superfamily
GI364_07010	COG4166	transmembrane transport
GI364_07015	COG2362	D-Aminopeptidase
GI364_07020	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GI364_07025	COG4990	cell redox homeostasis
GI364_07050	COG1733	regulation of RNA biosynthetic process
GI364_07060	COG1482	cell wall glycoprotein biosynthetic process
GI364_07070	COG0133	tryptophan synthase activity
GI364_07080	COG2081	HI0933 family
GI364_07085	COG1979	alcohol dehydrogenase
GI364_07090	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GI364_07105	COG0109	protoheme IX farnesyltransferase activity
GI364_07110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GI364_07120	COG1830	Aldolase
GI364_07125	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GI364_07140	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GI364_07145	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GI364_07155	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GI364_07160	COG0131	Imidazoleglycerol-phosphate dehydratase
GI364_07165	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GI364_07170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GI364_07175	COG0107	imidazoleglycerol-phosphate synthase activity
GI364_07180	COG0140	phosphoribosyl-ATP diphosphatase activity
GI364_07180	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GI364_07195	COG1695	Transcriptional regulator
GI364_07205	COG2318	DinB family
GI364_07215	COG1279	arginine transmembrane transporter activity
GI364_07225	COG1122	ATPase activity
GI364_07240	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_07245	COG1309	transcriptional regulator
GI364_07250	COG0583	DNA-binding transcription factor activity
GI364_07255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GI364_07260	COG0482	sulfurtransferase activity
GI364_07275	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GI364_07280	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GI364_07285	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GI364_07300	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GI364_07310	COG1960	acyl-CoA dehydrogenase activity
GI364_07315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GI364_07320	COG2873	o-acetylhomoserine
GI364_07325	COG0460	homoserine dehydrogenase
GI364_07340	COG1022	Amp-dependent synthetase and ligase
GI364_07360	COG2818	Glycosylase
GI364_07365	COG2155	Conserved Protein
GI364_07380	COG1940	carbohydrate kinase activity
GI364_07395	COG0395	ABC-type sugar transport system, permease component
GI364_07405	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GI364_07410	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GI364_07415	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_07420	COG0800	Aldolase
GI364_07425	COG0363	glucosamine-6-phosphate deaminase activity
GI364_07435	COG1295	ribonuclease BN
GI364_07440	COG1764	response to oxidative stress
GI364_07445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GI364_07460	COG1363	Peptidase, m42
GI364_07465	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GI364_07470	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GI364_07490	COG0577	efflux transmembrane transporter activity
GI364_07495	COG1136	(ABC) transporter
GI364_07515	COG0726	polysaccharide deacetylase
GI364_07525	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI364_07530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_07530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_07540	COG0348	domain, Protein
GI364_07555	COG1234	tRNA 3'-trailer cleavage
GI364_07560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GI364_07565	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GI364_07595	COG0167	dihydroorotate dehydrogenase activity
GI364_07600	COG1595	DNA-templated transcription, initiation
GI364_07615	COG0686	Belongs to the AlaDH PNT family
GI364_07620	COG2151	metal-sulfur cluster biosynthetic enzyme
GI364_07625	COG0396	ATPase activity
GI364_07630	COG0719	Fe-S assembly protein
GI364_07635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GI364_07640	COG0822	iron-sulfur transferase activity
GI364_07645	COG0719	Fe-S assembly protein
GI364_07655	COG1959	2 iron, 2 sulfur cluster binding
GI364_07670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI364_07675	COG1309	transcriptional regulator
GI364_07680	COG2086	electron transfer activity
GI364_07685	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GI364_07690	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GI364_07710	COG0626	cystathionine gamma-synthase activity
GI364_07715	COG2986	histidine ammonia-lyase
GI364_07720	COG0114	fumarate hydratase activity
GI364_07725	COG1506	peptidase
GI364_07725	COG4946	Tricorn protease homolog
GI364_07725	COG0823	Involved in the tonB-independent uptake of proteins
GI364_07730	COG0483	inositol monophosphate 1-phosphatase activity
GI364_07735	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GI364_07740	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GI364_07755	COG0069	glutamate synthase activity
GI364_07760	COG0297	glycogen (starch) synthase activity
GI364_07765	COG0189	ligase activity
GI364_07770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GI364_07770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GI364_07785	COG0673	inositol 2-dehydrogenase activity
GI364_07795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GI364_07835	COG1086	Polysaccharide biosynthesis protein
GI364_07855	COG1215	transferase activity, transferring glycosyl groups
GI364_07870	COG0463	Glycosyl transferase, family 2
GI364_07895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GI364_07920	COG0587	DNA-directed DNA polymerase activity
GI364_07940	COG0537	adenosine 5'-monophosphoramidase activity
GI364_07950	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI364_07950	COG1024	Enoyl-CoA hydratase
GI364_07955	COG0183	Belongs to the thiolase family
GI364_07960	COG1960	acyl-CoA dehydrogenase activity
GI364_07965	COG3584	3D domain protein
GI364_07970	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GI364_07980	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI364_07980	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI364_07980	COG1703	isobutyryl-CoA mutase activity
GI364_07985	COG0477	Major facilitator Superfamily
GI364_08005	COG0612	Peptidase, M16
GI364_08010	COG0612	Peptidase, M16
GI364_08020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GI364_08030	COG0602	queuosine metabolic process
GI364_08035	COG0720	synthase
GI364_08040	COG2233	PERMEase
GI364_08055	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_08075	COG1956	GAF domain-containing protein
GI364_08085	COG1193	negative regulation of DNA recombination
GI364_08095	COG0772	Belongs to the SEDS family
GI364_08105	COG0772	Belongs to the SEDS family
GI364_08110	COG0456	acetyltransferase
GI364_08115	COG0477	Major facilitator Superfamily
GI364_08125	COG1982	Orn Lys Arg decarboxylase major
GI364_08130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GI364_08135	COG0316	Belongs to the HesB IscA family
GI364_08140	COG1078	dGTPase activity
GI364_08145	COG0586	Pfam SNARE associated Golgi protein
GI364_08150	COG1215	transferase activity, transferring glycosyl groups
GI364_08155	COG3377	Domain of unknown function (DUF1805)
GI364_08160	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GI364_08170	COG0494	nUDIX hydrolase
GI364_08175	COG1013	pyruvate-flavodoxin oxidoreductase activity
GI364_08180	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GI364_08180	COG0674	pyruvate-flavodoxin oxidoreductase activity
GI364_08190	COG3584	3D domain protein
GI364_08195	COG0444	Belongs to the ABC transporter superfamily
GI364_08200	COG4608	Belongs to the ABC transporter superfamily
GI364_08205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_08210	COG0601	transmembrane transport
GI364_08215	COG0747	negative chemotaxis
GI364_08235	COG4974	Belongs to the 'phage' integrase family
GI364_08285	COG2199	diguanylate cyclase activity
GI364_08285	COG2203	Gaf domain
GI364_08295	COG1309	transcriptional regulator
GI364_08330	COG0640	Transcriptional regulator
GI364_08335	COG0697	spore germination
GI364_08345	COG1733	regulation of RNA biosynthetic process
GI364_08350	COG2259	Doxx family
GI364_08375	COG0697	spore germination
GI364_08380	COG0655	NAD(P)H dehydrogenase (quinone) activity
GI364_08385	COG4221	oxidoreductase activity
GI364_08395	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GI364_08400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GI364_08405	COG1272	protein, Hemolysin III
GI364_08460	COG3586	endonuclease activity
GI364_08505	COG2002	toxin-antitoxin pair type II binding
GI364_08530	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_08585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GI364_08605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GI364_08640	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GI364_08650	COG2378	regulation of single-species biofilm formation
GI364_08685	COG2508	Transcriptional regulator
GI364_08690	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GI364_08735	COG1653	transport
GI364_08740	COG1175	transmembrane transport
GI364_08745	COG0395	ABC-type sugar transport system, permease component
GI364_08750	COG2188	Transcriptional regulator
GI364_08760	COG0205	6-phosphofructokinase activity
GI364_08770	COG1012	belongs to the aldehyde dehydrogenase family
GI364_08775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GI364_08780	COG2721	sulfolactate sulfo-lyase activity
GI364_08785	COG2721	sulfolactate sulfo-lyase activity
GI364_08790	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GI364_08795	COG2186	Transcriptional regulator
GI364_08820	COG3340	Belongs to the peptidase S51 family
GI364_08855	COG1233	COG1233 Phytoene dehydrogenase and related
GI364_08910	COG0179	Fumarylacetoacetate (FAA) hydrolase
GI364_08915	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_08925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GI364_08930	COG1113	amino acid transport
GI364_08950	COG1595	DNA-templated transcription, initiation
GI364_08960	COG0477	Major facilitator Superfamily
GI364_08965	COG1940	carbohydrate kinase activity
GI364_08980	COG0395	ABC-type sugar transport system, permease component
GI364_08990	COG0673	inositol 2-dehydrogenase activity
GI364_09010	COG1061	Type III restriction enzyme res subunit
GI364_09040	COG3250	beta-galactosidase activity
GI364_09045	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GI364_09050	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GI364_09080	COG1082	Xylose isomerase domain protein TIM barrel
GI364_09110	COG1737	Transcriptional regulator
GI364_09115	COG4166	transmembrane transport
GI364_09120	COG0601	transmembrane transport
GI364_09125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_09130	COG0444	Belongs to the ABC transporter superfamily
GI364_09135	COG4608	Belongs to the ABC transporter superfamily
GI364_09140	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GI364_09145	COG0363	glucosamine-6-phosphate deaminase activity
GI364_09155	COG0673	inositol 2-dehydrogenase activity
GI364_09165	COG0673	inositol 2-dehydrogenase activity
GI364_09195	COG0673	inositol 2-dehydrogenase activity
GI364_09200	COG1609	Transcriptional regulator
GI364_09210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GI364_09215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GI364_09215	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GI364_09220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GI364_09235	COG1069	ribulokinase activity
GI364_09240	COG2271	Major facilitator Superfamily
GI364_09255	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GI364_09265	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_09270	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GI364_09275	COG0420	3'-5' exonuclease activity
GI364_09280	COG0419	ATPase involved in DNA repair
GI364_09285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GI364_09295	COG2226	methyltransferase
GI364_09305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_09315	COG0653	protein targeting
GI364_09320	COG3483	tryptophan 2,3-dioxygenase activity
GI364_09330	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GI364_09360	COG0493	'glutamate synthase
GI364_09380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GI364_09385	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GI364_09390	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GI364_09390	COG3608	succinylglutamate desuccinylase aspartoacylase
GI364_09400	COG0561	phosphatase activity
GI364_09405	COG2267	carboxylic ester hydrolase activity
GI364_09425	COG0674	pyruvate-flavodoxin oxidoreductase activity
GI364_09455	COG1914	H( )-stimulated, divalent metal cation uptake system
GI364_09515	COG0512	Glutamine amidotransferase of anthranilate synthase
GI364_09530	COG4974	Belongs to the 'phage' integrase family
GI364_09645	COG2084	Dehydrogenase
GI364_09650	COG1349	DNA-binding transcription factor activity
GI364_09660	COG2376	Dihydroxyacetone kinase
GI364_09665	COG1461	Dihydroxyacetone kinase
GI364_09670	COG0698	ribose 5-phosphate isomerase
GI364_09675	COG1733	regulation of RNA biosynthetic process
GI364_09695	COG1612	heme a metabolic process
GI364_09720	COG0427	acetyl-CoA hydrolase
GI364_09735	COG0196	riboflavin kinase activity
GI364_09755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI364_09760	COG1063	alcohol dehydrogenase
GI364_09765	COG2508	Transcriptional regulator
GI364_09775	COG0577	efflux transmembrane transporter activity
GI364_09775	COG1136	(ABC) transporter
GI364_09780	COG1136	(ABC) transporter
GI364_09780	COG0577	efflux transmembrane transporter activity
GI364_09790	COG3383	formate dehydrogenase (NAD+) activity
GI364_09810	COG0583	DNA-binding transcription factor activity
GI364_09830	COG1388	LysM domain
GI364_09830	COG3858	chitin binding
GI364_09835	COG0436	Aminotransferase
GI364_09840	COG1522	sequence-specific DNA binding
GI364_09850	COG2814	Major facilitator Superfamily
GI364_09865	COG1832	CoA-binding protein
GI364_09880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GI364_09885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GI364_09895	COG0069	glutamate synthase activity
GI364_09895	COG0067	glutamate synthase
GI364_09895	COG0070	glutamate synthase
GI364_09900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GI364_09905	COG0137	argininosuccinate synthase activity
GI364_09910	COG0165	Argininosuccinate lyase
GI364_09920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GI364_09925	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GI364_09950	COG3906	Belongs to the UPF0473 family
GI364_10005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GI364_10015	COG1104	cysteine desulfurase activity
GI364_10020	COG0301	tRNA thio-modification
GI364_10045	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_10050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GI364_10055	COG1024	Enoyl-CoA hydratase
GI364_10060	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GI364_10065	COG2001	Belongs to the MraZ family
GI364_10070	COG0275	rRNA processing
GI364_10080	COG0768	penicillin binding
GI364_10085	COG0768	penicillin binding
GI364_10095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GI364_10100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GI364_10105	COG0772	Belongs to the SEDS family
GI364_10115	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GI364_10120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GI364_10125	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GI364_10140	COG3856	small basic protein
GI364_10145	COG0849	cell division
GI364_10150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GI364_10160	COG1191	sigma factor activity
GI364_10165	COG1191	sigma factor activity
GI364_10170	COG1873	PFAM PRC-barrel domain
GI364_10175	COG1496	oxidoreductase activity
GI364_10180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GI364_10185	COG0762	integral membrane protein
GI364_10190	COG2302	S4 RNA-binding domain
GI364_10195	COG3599	regulation of cell shape
GI364_10200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GI364_10205	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GI364_10210	COG0564	pseudouridine synthase activity
GI364_10215	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GI364_10220	COG0540	Belongs to the ATCase OTCase family
GI364_10225	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GI364_10230	COG0505	Belongs to the CarA family
GI364_10240	COG0284	orotidine-5'-phosphate decarboxylase activity
GI364_10255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GI364_10270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GI364_10275	COG1561	YicC-like family, N-terminal region
GI364_10285	COG0194	GDP metabolic process
GI364_10290	COG1758	RNA polymerase activity
GI364_10295	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GI364_10300	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GI364_10305	COG0242	peptide deformylase activity
GI364_10310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GI364_10315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GI364_10315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GI364_10320	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GI364_10325	COG0631	protein serine/threonine phosphatase activity
GI364_10330	COG0515	serine threonine protein kinase
GI364_10330	COG2815	serine threonine protein kinase
GI364_10335	COG1162	GTPase activity
GI364_10340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GI364_10350	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GI364_10355	COG1302	Protein conserved in bacteria
GI364_10360	COG1461	Dihydroxyacetone kinase
GI364_10365	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GI364_10375	COG0688	phosphatidylethanolamine metabolic process
GI364_10385	COG0438	transferase activity, transferring glycosyl groups
GI364_10400	COG0742	ribosomal rna small subunit methyltransferase
GI364_10405	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GI364_10410	COG1752	Esterase of the alpha-beta hydrolase superfamily
GI364_10420	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GI364_10425	COG1349	DNA-binding transcription factor activity
GI364_10430	COG0416	fatty acid biosynthetic process
GI364_10435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GI364_10440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GI364_10445	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_10450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GI364_10455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GI364_10465	COG1196	nuclear chromosome segregation
GI364_10470	COG0552	protein localization to endoplasmic reticulum
GI364_10475	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GI364_10480	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GI364_10485	COG0228	four-way junction DNA binding
GI364_10505	COG0336	Belongs to the RNA methyltransferase TrmD family
GI364_10530	COG3385	transposase activity
GI364_10540	COG0564	pseudouridine synthase activity
GI364_10560	COG1960	acyl-CoA dehydrogenase activity
GI364_10565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GI364_10570	COG0656	L-ascorbic acid biosynthetic process
GI364_10575	COG0824	Thioesterase
GI364_10580	COG0739	heme binding
GI364_10595	COG1607	acyl-coa hydrolase
GI364_10605	COG0335	large ribosomal subunit rRNA binding
GI364_10615	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GI364_10630	COG0792	nuclease activity
GI364_10645	COG0045	succinate-CoA ligase (ADP-forming) activity
GI364_10650	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GI364_10655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GI364_10655	COG0758	DNA mediated transformation
GI364_10660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GI364_10665	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GI364_10670	COG4974	Belongs to the 'phage' integrase family
GI364_10675	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GI364_10680	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GI364_10700	COG1677	Flagellar hook-basal body complex protein FliE
GI364_10705	COG1766	The M ring may be actively involved in energy transduction
GI364_10710	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GI364_10720	COG1157	protein secretion by the type III secretion system
GI364_10750	COG4786	Flagellar basal body rod
GI364_10765	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GI364_10770	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GI364_10770	COG1776	CheC inhibitor of MCP methylation
GI364_10775	COG2201	protein-glutamate methylesterase activity
GI364_10785	COG1338	Plays a role in the flagellum-specific transport system
GI364_10790	COG1987	bacterial-type flagellum assembly
GI364_10795	COG1684	flagellar biosynthetic protein fliR
GI364_10800	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GI364_10805	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GI364_10810	COG1419	protein localization to endoplasmic reticulum
GI364_10820	COG0835	chemotaxis
GI364_10825	COG1776	CheC inhibitor of MCP methylation
GI364_10830	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GI364_10840	COG0052	Belongs to the universal ribosomal protein uS2 family
GI364_10845	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GI364_10850	COG0528	UMP kinase activity
GI364_10855	COG0233	cytoplasmic translational termination
GI364_10860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GI364_10865	COG4589	Belongs to the CDS family
GI364_10870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GI364_10875	COG0750	zinc metalloprotease
GI364_10880	COG0442	prolyl-tRNA aminoacylation
GI364_10885	COG2176	DNA-directed DNA polymerase activity
GI364_10890	COG0077	Prephenate dehydratase
GI364_10910	COG0697	spore germination
GI364_10915	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GI364_10915	COG0069	glutamate synthase activity
GI364_10920	COG1217	gtp-binding protein TYPA
GI364_10925	COG0779	Required for maturation of 30S ribosomal subunits
GI364_10930	COG0195	Participates in both transcription termination and antitermination
GI364_10935	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GI364_10945	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GI364_10950	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GI364_10960	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GI364_10965	COG0196	riboflavin kinase activity
GI364_10975	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GI364_10980	COG1185	polyribonucleotide nucleotidyltransferase activity
GI364_10985	COG0726	polysaccharide deacetylase
GI364_10990	COG0612	Peptidase, M16
GI364_10995	COG0756	dUTP diphosphatase activity
GI364_11010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GI364_11020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GI364_11025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GI364_11030	COG0527	aspartate kinase activity
GI364_11035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GI364_11040	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GI364_11045	COG0740	serine-type endopeptidase activity
GI364_11055	COG1674	ftsk spoiiie
GI364_11055	COG4980	gas vesicle protein
GI364_11080	COG1426	Protein conserved in bacteria
GI364_11085	COG1666	GTP binding
GI364_11090	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GI364_11095	COG1058	Belongs to the CinA family
GI364_11095	COG1546	Belongs to the CinA family
GI364_11105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GI364_11110	COG2137	regulation of response to DNA damage stimulus
GI364_11115	COG1418	mRNA catabolic process
GI364_11120	COG1692	metallophosphoesterase
GI364_11125	COG2359	stage V sporulation protein S
GI364_11135	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI364_11155	COG1396	sequence-specific DNA binding
GI364_11160	COG1396	sequence-specific DNA binding
GI364_11195	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GI364_11295	COG3331	DNA recombination
GI364_11450	COG3274	enterobacterial common antigen metabolic process
GI364_11495	COG0189	ligase activity
GI364_11510	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI364_11540	COG0697	spore germination
GI364_11555	COG2226	methyltransferase
GI364_11560	COG0189	ligase activity
GI364_11570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GI364_11580	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GI364_11585	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GI364_11590	COG2521	methyltransferase
GI364_11590	COG2136	Putative SAM-dependent methyltransferase
GI364_11595	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GI364_11670	COG0697	spore germination
GI364_11680	COG0464	growth
GI364_11700	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GI364_11705	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GI364_11710	COG0789	Transcriptional regulator
GI364_11715	COG0174	glutamine synthetase
GI364_11740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GI364_11745	COG3942	CHAP domain
GI364_11745	COG1388	LysM domain
GI364_11750	COG0646	methionine synthase
GI364_11750	COG1410	methionine synthase
GI364_11755	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GI364_11755	COG0646	methionine synthase
GI364_11765	COG0561	phosphatase activity
GI364_11770	COG0423	glycine-tRNA ligase activity
GI364_11785	COG2814	Major facilitator Superfamily
GI364_11790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GI364_11815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GI364_11820	COG2151	metal-sulfur cluster biosynthetic enzyme
GI364_11840	COG0446	pyridine nucleotide-disulphide oxidoreductase
GI364_11855	COG0425	Belongs to the sulfur carrier protein TusA family
GI364_11865	COG1113	amino acid transport
GI364_11870	COG2720	vancomycin resistance protein
GI364_11890	COG0095	Lipoate-protein ligase
GI364_11895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GI364_11915	COG1376	ErfK ybiS ycfS ynhG family protein
GI364_11930	COG1657	PFAM Prenyltransferase squalene oxidase
GI364_11940	COG0024	Methionine aminopeptidase
GI364_11950	COG0824	Thioesterase
GI364_11955	COG0693	protein deglycase activity
GI364_11965	COG1033	growth of symbiont in host cell
GI364_11965	COG2409	Drug exporters of the RND superfamily
GI364_11995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GI364_12000	COG0697	spore germination
GI364_12015	COG0316	Belongs to the HesB IscA family
GI364_12020	COG0494	nUDIX hydrolase
GI364_12030	COG1686	Belongs to the peptidase S11 family
GI364_12035	COG0367	asparagine synthase
GI364_12065	COG0428	transporter
GI364_12075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GI364_12090	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GI364_12095	COG1072	(Pantothenic acid kinase))
GI364_12100	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GI364_12115	COG0017	Asparaginyl-tRNA synthetase
GI364_12120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GI364_12140	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GI364_12150	COG0402	S-adenosylhomocysteine deaminase activity
GI364_12155	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GI364_12160	COG3285	dna ligase
GI364_12160	COG1793	dna ligase
GI364_12175	COG1199	ATP-dependent helicase activity
GI364_12175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GI364_12185	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GI364_12185	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GI364_12190	COG0617	tRNA 3'-terminal CCA addition
GI364_12195	COG0438	transferase activity, transferring glycosyl groups
GI364_12200	COG1803	Methylglyoxal synthase
GI364_12205	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GI364_12215	COG1694	Mazg nucleotide pyrophosphohydrolase
GI364_12220	COG3314	Sporulation integral membrane protein YlbJ
GI364_12225	COG1968	undecaprenyl-diphosphatase activity
GI364_12230	COG3949	Membrane
GI364_12235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GI364_12255	COG5582	Belongs to the UPF0302 family
GI364_12275	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GI364_12280	COG0159	tryptophan synthase activity
GI364_12285	COG0133	tryptophan synthase activity
GI364_12290	COG0135	phosphoribosylanthranilate isomerase activity
GI364_12295	COG0134	indole-3-glycerol-phosphate synthase activity
GI364_12300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GI364_12305	COG4401	Chorismate mutase type I
GI364_12310	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GI364_12320	COG1335	isochorismatase
GI364_12335	COG1363	Peptidase, m42
GI364_12340	COG0564	pseudouridine synthase activity
GI364_12365	COG0740	serine-type endopeptidase activity
GI364_12390	COG1132	(ABC) transporter
GI364_12395	COG1132	(ABC) transporter
GI364_12400	COG2323	membrane
GI364_12405	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GI364_12415	COG0105	UTP biosynthetic process
GI364_12420	COG0142	geranyltranstransferase activity
GI364_12440	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GI364_12445	COG0509	glycine decarboxylation via glycine cleavage system
GI364_12450	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GI364_12455	COG1160	GTP binding
GI364_12475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GI364_12490	COG2959	enzyme of heme biosynthesis
GI364_12505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GI364_12510	COG4862	establishment of competence for transformation
GI364_12515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GI364_12520	COG1609	Transcriptional regulator
GI364_12530	COG0210	DNA helicase
GI364_12530	COG0210	DNA helicase
GI364_12540	COG2226	methyltransferase
GI364_12550	COG1388	LysM domain
GI364_12550	COG0791	NLP P60 protein
GI364_12560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GI364_12585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GI364_12590	COG3459	Glycosyltransferase 36 associated
GI364_12595	COG1063	alcohol dehydrogenase
GI364_12610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GI364_12615	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_12620	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_12625	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GI364_12630	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GI364_12670	COG2427	Protein of unknown function (DUF1641)
GI364_12675	COG3383	formate dehydrogenase (NAD+) activity
GI364_12685	COG0393	Putative heavy-metal-binding
GI364_12690	COG0393	Putative heavy-metal-binding
GI364_12695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GI364_12705	COG1012	belongs to the aldehyde dehydrogenase family
GI364_12710	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GI364_12715	COG2151	metal-sulfur cluster biosynthetic enzyme
GI364_12730	COG3396	Phenylacetate-CoA oxygenase
GI364_12745	COG3383	formate dehydrogenase (NAD+) activity
GI364_12750	COG2814	Major facilitator Superfamily
GI364_12760	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_12775	COG1842	Phage shock protein A
GI364_12780	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GI364_12785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GI364_12815	COG0708	Exodeoxyribonuclease III
GI364_12820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI364_12840	COG2339	peptidase activity
GI364_12855	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GI364_12870	COG5002	protein histidine kinase activity
GI364_12875	COG0745	RESPONSE REGULATOR receiver
GI364_12890	COG1187	pseudouridine synthase activity
GI364_12895	COG0700	Nucleoside recognition
GI364_12900	COG2715	membrane protein required for spore maturation
GI364_12905	COG3874	Sporulation protein YtfJ
GI364_12915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GI364_12920	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GI364_12925	COG1994	Peptidase M50
GI364_12945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GI364_12955	COG1191	sigma factor activity
GI364_12960	COG2172	sigma factor antagonist activity
GI364_12975	COG1686	Belongs to the peptidase S11 family
GI364_12985	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GI364_12990	COG4974	Belongs to the 'phage' integrase family
GI364_13005	COG1300	Membrane
GI364_13010	COG1379	DNA repair
GI364_13015	COG0494	nUDIX hydrolase
GI364_13020	COG1113	amino acid transport
GI364_13025	COG2195	Cleaves the N-terminal amino acid of tripeptides
GI364_13030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GI364_13035	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI364_13035	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI364_13040	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI364_13040	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI364_13045	COG0321	lipoyl(octanoyl) transferase activity
GI364_13050	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GI364_13055	COG0508	dehydrogenase complex catalyzes the overall conversion of
GI364_13060	COG0022	dehydrogenase e1 component
GI364_13065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GI364_13070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GI364_13080	COG3290	protein histidine kinase activity
GI364_13080	COG3829	transcription factor binding
GI364_13100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_13115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GI364_13125	COG1131	(ABC) transporter
GI364_13135	COG1138	Cytochrome C-type biogenesis protein
GI364_13140	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GI364_13155	COG2050	protein possibly involved in aromatic compounds catabolism
GI364_13160	COG0508	dehydrogenase complex catalyzes the overall conversion of
GI364_13170	COG1902	pentaerythritol trinitrate reductase activity
GI364_13175	COG2226	methyltransferase
GI364_13180	COG0456	acetyltransferase
GI364_13185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GI364_13190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GI364_13195	COG0640	Transcriptional regulator
GI364_13205	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GI364_13210	COG1131	(ABC) transporter
GI364_13230	COG1595	DNA-templated transcription, initiation
GI364_13240	COG5001	Diguanylate cyclase
GI364_13240	COG3300	MHYT domain
GI364_13250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GI364_13255	COG0456	acetyltransferase
GI364_13260	COG0745	RESPONSE REGULATOR receiver
GI364_13265	COG0750	zinc metalloprotease
GI364_13270	COG0497	DNA recombination
GI364_13275	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GI364_13285	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GI364_13290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GI364_13305	COG1722	exodeoxyribonuclease VII activity
GI364_13310	COG1570	exodeoxyribonuclease VII activity
GI364_13315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GI364_13320	COG0492	ferredoxin-NADP+ reductase activity
GI364_13325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GI364_13330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GI364_13345	COG1302	Protein conserved in bacteria
GI364_13350	COG0439	Biotin carboxylase
GI364_13355	COG0511	ligase activity, forming carbon-carbon bonds
GI364_13395	COG3854	ATPases associated with a variety of cellular activities
GI364_13400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GI364_13405	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GI364_13410	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GI364_13415	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GI364_13420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GI364_13425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GI364_13435	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GI364_13440	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GI364_13475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GI364_13485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GI364_13495	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GI364_13505	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GI364_13510	COG1994	Peptidase M50
GI364_13520	COG2894	cell division
GI364_13525	COG0850	regulation of cytokinetic process
GI364_13540	COG1077	Cell shape determining protein MreB Mrl
GI364_13545	COG2003	Belongs to the UPF0758 family
GI364_13560	COG3584	3D domain protein
GI364_13560	COG3583	domain protein
GI364_13565	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GI364_13580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GI364_13585	COG0285	dihydrofolate synthase activity
GI364_13590	COG0525	valine-tRNA ligase activity
GI364_13620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GI364_13625	COG0113	porphobilinogen synthase activity
GI364_13635	COG0181	hydroxymethylbilane synthase activity
GI364_13640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GI364_13645	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GI364_13650	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GI364_13660	COG0470	DNA polymerase III
GI364_13660	COG1067	ATP-dependent peptidase activity
GI364_13665	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GI364_13670	COG0740	serine-type endopeptidase activity
GI364_13675	COG0544	peptidyl-prolyl cis-trans isomerase activity
GI364_13700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GI364_13705	COG1846	Transcriptional regulator
GI364_13710	COG2197	response regulator
GI364_13715	COG0484	heat shock protein binding
GI364_13725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GI364_13730	COG1053	succinate dehydrogenase
GI364_13735	COG2009	succinate dehydrogenase
GI364_13740	COG0322	excinuclease ABC activity
GI364_13765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GI364_13775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GI364_13780	COG0387	Pfam Sodium calcium exchanger
GI364_13825	COG1846	Transcriptional regulator
GI364_13830	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GI364_13845	COG2226	methyltransferase
GI364_13870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GI364_13880	COG5002	protein histidine kinase activity
GI364_13890	COG1794	racemase activity, acting on amino acids and derivatives
GI364_13925	COG0583	DNA-binding transcription factor activity
GI364_13960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_13965	COG1418	mRNA catabolic process
GI364_13990	COG1227	inorganic diphosphatase activity
GI364_14000	COG0442	prolyl-tRNA aminoacylation
GI364_14020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GI364_14025	COG0475	glutathione-regulated potassium exporter activity
GI364_14025	COG0569	domain protein
GI364_14035	COG2205	protein histidine kinase activity
GI364_14040	COG0745	RESPONSE REGULATOR receiver
GI364_14090	COG0640	Transcriptional regulator
GI364_14100	COG4555	ABC transporter
GI364_14120	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_14125	COG2267	carboxylic ester hydrolase activity
GI364_14140	COG0583	DNA-binding transcription factor activity
GI364_14155	COG2211	Major facilitator Superfamily
GI364_14160	COG0730	response to heat
GI364_14165	COG2046	Belongs to the sulfate adenylyltransferase family
GI364_14170	COG0175	sulfate reduction
GI364_14175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GI364_14220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GI364_14225	COG0647	UMP catabolic process
GI364_14230	COG2096	Adenosyltransferase
GI364_14250	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GI364_14255	COG4187	Peptidase family M20/M25/M40
GI364_14265	COG3336	cytochrome c oxidase
GI364_14280	COG3409	Peptidoglycan-binding domain 1 protein
GI364_14280	COG3773	Cell wall hydrolase
GI364_14285	COG0463	Glycosyl transferase, family 2
GI364_14300	COG1566	PFAM secretion protein HlyD family protein
GI364_14305	COG2814	Major facilitator Superfamily
GI364_14310	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GI364_14320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GI364_14325	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GI364_14335	COG1388	LysM domain
GI364_14335	COG0791	NLP P60 protein
GI364_14340	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GI364_14345	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GI364_14370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GI364_14375	COG2814	Major facilitator Superfamily
GI364_14390	COG0714	Associated with various cellular activities
GI364_14395	COG3263	regulation of cellular component size
GI364_14410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI364_14415	COG0596	Alpha beta hydrolase
GI364_14420	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GI364_14425	COG1169	isochorismate synthase
GI364_14435	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GI364_14440	COG1575	Belongs to the MenA family. Type 1 subfamily
GI364_14450	COG0384	phenazine biosynthesis protein PhzF
GI364_14465	COG0531	amino acid
GI364_14475	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GI364_14485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI364_14490	COG1937	Protein conserved in bacteria
GI364_14495	COG2217	Heavy metal translocating P-type atpase
GI364_14535	COG1686	Belongs to the peptidase S11 family
GI364_14555	COG1435	thymidine kinase activity
GI364_14560	COG0640	Transcriptional regulator
GI364_14580	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GI364_14595	COG2808	Putative FMN-binding domain
GI364_14600	COG0531	amino acid
GI364_14655	COG0390	transport system, permease component
GI364_14660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GI364_14665	COG1131	(ABC) transporter
GI364_14670	COG1511	domain protein
GI364_14670	COG0842	Transport permease protein
GI364_14675	COG1309	transcriptional regulator
GI364_14710	COG2009	succinate dehydrogenase
GI364_14715	COG2814	Major facilitator Superfamily
GI364_14720	COG1959	2 iron, 2 sulfur cluster binding
GI364_14730	COG0730	response to heat
GI364_14735	COG0243	molybdopterin cofactor binding
GI364_14740	COG0437	4 iron, 4 sulfur cluster binding
GI364_14745	COG0583	DNA-binding transcription factor activity
GI364_14765	COG0425	Belongs to the sulfur carrier protein TusA family
GI364_14770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_14770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_14775	COG1012	belongs to the aldehyde dehydrogenase family
GI364_14790	COG1510	regulation of RNA biosynthetic process
GI364_14800	COG0492	ferredoxin-NADP+ reductase activity
GI364_14810	COG0789	Transcriptional regulator
GI364_14815	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GI364_14825	COG2814	Major facilitator Superfamily
GI364_14875	COG0697	spore germination
GI364_14880	COG5002	protein histidine kinase activity
GI364_14890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GI364_14905	COG0531	amino acid
GI364_14910	COG0583	DNA-binding transcription factor activity
GI364_14940	COG0477	Major facilitator Superfamily
GI364_14950	COG0180	Tryptophanyl-tRNA synthetase
GI364_14985	COG2814	Major facilitator Superfamily
GI364_14990	COG2814	Major facilitator Superfamily
GI364_15005	COG4974	Belongs to the 'phage' integrase family
GI364_15045	COG2002	toxin-antitoxin pair type II binding
GI364_15050	COG3328	transposase activity
GI364_15145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_15150	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GI364_15155	COG1683	Conserved Protein
GI364_15190	COG4974	Belongs to the 'phage' integrase family
GI364_15205	COG4974	Belongs to the 'phage' integrase family
GI364_15210	COG4974	Belongs to the 'phage' integrase family
GI364_15235	COG2002	toxin-antitoxin pair type II binding
GI364_15305	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GI364_15320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GI364_15325	COG0305	Participates in initiation and elongation during chromosome replication
GI364_15325	COG0358	DNA primase activity
GI364_15330	COG0574	Belongs to the PEP-utilizing enzyme family
GI364_15330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GI364_15335	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GI364_15340	COG0517	IMP dehydrogenase activity
GI364_15345	COG1381	Involved in DNA repair and RecF pathway recombination
GI364_15355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GI364_15360	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GI364_15365	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GI364_15370	COG1480	7TM receptor with intracellular HD hydrolase
GI364_15375	COG1702	phosphate starvation-inducible protein PhoH
GI364_15395	COG1610	YqeY-like protein
GI364_15400	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GI364_15405	COG1283	sodium-dependent phosphate transmembrane transporter activity
GI364_15410	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GI364_15415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GI364_15420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GI364_15425	COG2264	protein methyltransferase activity
GI364_15440	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GI364_15445	COG1420	regulation of RNA biosynthetic process
GI364_15450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GI364_15455	COG0481	GTPase activity
GI364_15465	COG0741	lytic transglycosylase activity
GI364_15475	COG0268	Binds directly to 16S ribosomal RNA
GI364_15480	COG1466	dna polymerase III delta subunit
GI364_15485	COG1252	NADH dehydrogenase
GI364_15505	COG1321	iron dependent repressor
GI364_15515	COG0799	negative regulation of ribosome biogenesis
GI364_15520	COG1713	HD superfamily hydrolase involved in NAD metabolism
GI364_15525	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GI364_15530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GI364_15535	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GI364_15540	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GI364_15550	COG0768	penicillin binding
GI364_15560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GI364_15565	COG4472	Bacterial protein of unknown function (DUF965)
GI364_15570	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GI364_15580	COG0628	permease
GI364_15585	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GI364_15590	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GI364_15600	COG1104	cysteine desulfurase activity
GI364_15605	COG1959	2 iron, 2 sulfur cluster binding
GI364_15625	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GI364_15630	COG0124	histidyl-tRNA synthetase
GI364_15640	COG1921	L-seryl-tRNASec selenium transferase activity
GI364_15665	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_15680	COG1131	(ABC) transporter
GI364_15695	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GI364_15700	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GI364_15700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GI364_15705	COG0183	Belongs to the thiolase family
GI364_15730	COG2226	methyltransferase
GI364_15740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GI364_15750	COG0667	Aldo Keto reductase
GI364_15755	COG0303	'Molybdopterin
GI364_15760	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GI364_15765	COG1131	(ABC) transporter
GI364_15775	COG1131	(ABC) transporter
GI364_15780	COG1725	Transcriptional regulator
GI364_15790	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GI364_15825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GI364_15840	COG2211	Major facilitator Superfamily
GI364_15860	COG0531	amino acid
GI364_15865	COG1309	transcriptional regulator
GI364_15870	COG0477	Major facilitator Superfamily
GI364_15875	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
GI364_15880	COG1074	ATP-dependent DNA helicase activity
GI364_15885	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GI364_15890	COG4717	serine-type aminopeptidase activity
GI364_15895	COG0420	3'-5' exonuclease activity
GI364_15900	COG2130	NADP-dependent
GI364_15905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GI364_15925	COG1321	iron dependent repressor
GI364_15940	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GI364_15945	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GI364_15950	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GI364_15965	COG4129	membrane
GI364_15980	COG0667	Aldo Keto reductase
GI364_16010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GI364_16015	COG0569	domain protein
GI364_16025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_16030	COG1490	D-aminoacyl-tRNA deacylase activity
GI364_16035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GI364_16040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GI364_16045	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GI364_16045	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GI364_16050	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GI364_16055	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GI364_16060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GI364_16070	COG2244	polysaccharide biosynthetic process
GI364_16075	COG2323	membrane
GI364_16095	COG0343	queuine tRNA-ribosyltransferase activity
GI364_16100	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GI364_16105	COG3693	PFAM glycoside hydrolase, family 10
GI364_16110	COG1191	sigma factor activity
GI364_16115	COG2255	four-way junction helicase activity
GI364_16120	COG0632	four-way junction helicase activity
GI364_16135	COG0217	transcriptional regulatory protein
GI364_16165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GI364_16170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GI364_16175	COG1193	negative regulation of DNA recombination
GI364_16190	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GI364_16195	COG0072	phenylalanine-tRNA ligase activity
GI364_16195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GI364_16200	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GI364_16205	COG0667	Aldo Keto reductase
GI364_16210	COG0697	spore germination
GI364_16215	COG2211	Major facilitator Superfamily
GI364_16220	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GI364_16225	COG2723	6-phospho-beta-galactosidase activity
GI364_16230	COG1486	melibiose metabolic process
GI364_16250	COG0644	oxidoreductase
GI364_16255	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GI364_16285	COG1612	heme a metabolic process
GI364_16290	COG0109	protoheme IX farnesyltransferase activity
GI364_16310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GI364_16345	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GI364_16365	COG3253	May function as heme-dependent peroxidase
GI364_16370	COG0277	FAD linked oxidase domain protein
GI364_16375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GI364_16380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GI364_16390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_16405	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_16415	COG1172	Belongs to the binding-protein-dependent transport system permease family
GI364_16420	COG0559	Belongs to the binding-protein-dependent transport system permease family
GI364_16440	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GI364_16445	COG2814	Major facilitator Superfamily
GI364_16450	COG0789	Transcriptional regulator
GI364_16460	COG2183	response to ionizing radiation
GI364_16480	COG3511	phospholipase C
GI364_16490	COG0531	amino acid
GI364_16495	COG1760	l-serine dehydratase
GI364_16500	COG1760	l-serine dehydratase
GI364_16515	COG2966	Psort location CytoplasmicMembrane, score
GI364_16520	COG3610	response to peptide
GI364_16525	COG2124	cytochrome p450
GI364_16535	COG0577	efflux transmembrane transporter activity
GI364_16535	COG1136	(ABC) transporter
GI364_16540	COG0003	Pfam Anion-transporting ATPase
GI364_16570	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GI364_16575	COG1459	type II secretion system
GI364_16615	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GI364_16625	COG0673	inositol 2-dehydrogenase activity
GI364_16635	COG1024	Enoyl-CoA hydratase
GI364_16650	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_16655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GI364_16680	COG1960	acyl-CoA dehydrogenase activity
GI364_16700	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_16710	COG2030	dehydratase
GI364_16715	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_16725	COG1294	oxidase, subunit
GI364_16730	COG1271	oxidase subunit
GI364_16740	COG1414	Transcriptional regulator
GI364_16745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GI364_16750	COG0385	Bile acid
GI364_16760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GI364_16765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GI364_16770	COG2267	carboxylic ester hydrolase activity
GI364_16775	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GI364_16780	COG0402	S-adenosylhomocysteine deaminase activity
GI364_16795	COG2186	Transcriptional regulator
GI364_16825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GI364_16830	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GI364_16840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GI364_16845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GI364_16855	COG2376	Dihydroxyacetone kinase
GI364_16860	COG1461	Dihydroxyacetone kinase
GI364_16875	COG0668	transmembrane transport
GI364_16885	COG0745	RESPONSE REGULATOR receiver
GI364_16885	COG2972	Histidine kinase
GI364_16895	COG3239	Fatty acid desaturase
GI364_16935	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GI364_16940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GI364_16970	COG3546	catalase activity
GI364_16975	COG4846	Membrane protein involved in cytochrome C biogenesis
GI364_17000	COG0586	Pfam SNARE associated Golgi protein
GI364_17005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GI364_17010	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GI364_17015	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GI364_17025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GI364_17045	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GI364_17055	COG2272	Belongs to the type-B carboxylesterase lipase family
GI364_17070	COG1309	transcriptional regulator
GI364_17075	COG2814	Major facilitator Superfamily
GI364_17160	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GI364_17165	COG0457	Tetratricopeptide repeat
GI364_17165	COG0705	Rhomboid family
GI364_17175	COG0501	Belongs to the peptidase M48B family
GI364_17195	COG0517	IMP dehydrogenase activity
GI364_17205	COG2197	response regulator
GI364_17210	COG4585	Histidine kinase
GI364_17220	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GI364_17230	COG1809	phosphosulfolactate synthase activity
GI364_17235	COG1971	Probably functions as a manganese efflux pump
GI364_17240	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GI364_17255	COG0083	homoserine kinase activity
GI364_17260	COG0460	homoserine dehydrogenase
GI364_17270	COG0066	3-isopropylmalate dehydratase activity
GI364_17275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GI364_17280	COG0473	3-isopropylmalate dehydrogenase activity
GI364_17285	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GI364_17290	COG0440	acetolactate synthase activity
GI364_17295	COG0028	Belongs to the TPP enzyme family
GI364_17300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GI364_17325	COG2224	Isocitrate lyase
GI364_17330	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GI364_17340	COG1119	ATPase activity
GI364_17345	COG5002	protein histidine kinase activity
GI364_17355	COG0604	alcohol dehydrogenase
GI364_17365	COG3383	formate dehydrogenase (NAD+) activity
GI364_17370	COG3383	formate dehydrogenase (NAD+) activity
GI364_17420	COG1271	oxidase subunit
GI364_17425	COG1294	oxidase, subunit
GI364_17440	COG0730	response to heat
GI364_17460	COG3511	phospholipase C
GI364_17475	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_17495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GI364_17500	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GI364_17515	COG1584	GPR1 FUN34 yaaH family protein
GI364_17550	COG3971	2-oxopent-4-enoate hydratase activity
GI364_17570	COG1012	belongs to the aldehyde dehydrogenase family
GI364_17575	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GI364_17580	COG4638	Rieske (2fe-2S)
GI364_17585	COG2271	Major facilitator Superfamily
GI364_17590	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GI364_17600	COG3852	Histidine kinase
GI364_17605	COG1621	beta-fructofuranosidase activity
GI364_17615	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GI364_17625	COG1940	carbohydrate kinase activity
GI364_17630	COG0395	ABC-type sugar transport system, permease component
GI364_17635	COG1175	transmembrane transport
GI364_17655	COG4191	Histidine kinase
GI364_17680	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GI364_17695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GI364_17700	COG1388	LysM domain
GI364_17700	COG3858	chitin binding
GI364_17735	COG0640	Transcriptional regulator
GI364_17790	COG1388	LysM domain
GI364_17790	COG3858	chitin binding
GI364_17800	COG0640	Transcriptional regulator
GI364_17805	COG1971	Probably functions as a manganese efflux pump
GI364_17830	COG0714	Associated with various cellular activities
GI364_17855	COG1132	(ABC) transporter
GI364_17860	COG1132	(ABC) transporter
GI364_17870	COG1827	regulation of RNA biosynthetic process
GI364_17880	COG1757	Na H antiporter
GI364_17885	COG2155	Conserved Protein
GI364_17890	COG1011	Hydrolase
GI364_17895	COG2233	PERMEase
GI364_17905	COG2814	Major facilitator Superfamily
GI364_17915	COG0095	Lipoate-protein ligase
GI364_17920	COG0583	DNA-binding transcription factor activity
GI364_17930	COG0697	spore germination
GI364_17935	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GI364_17935	COG3264	Mechanosensitive ion channel
GI364_17955	COG2814	Major facilitator Superfamily
GI364_17965	COG2197	response regulator
GI364_17970	COG4585	Histidine kinase
GI364_17990	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GI364_17995	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GI364_18000	COG0835	chemotaxis
GI364_18005	COG0840	transmembrane signaling receptor activity
GI364_18010	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GI364_18035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GI364_18060	COG1845	cytochrome c oxidase, subunit III
GI364_18065	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GI364_18070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GI364_18075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI364_18080	COG2309	aminopeptidase activity
GI364_18090	COG2313	pseudouridylate synthase activity
GI364_18110	COG2205	protein histidine kinase activity
GI364_18115	COG0745	RESPONSE REGULATOR receiver
GI364_18125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI364_18130	COG0577	efflux transmembrane transporter activity
GI364_18130	COG1136	(ABC) transporter
GI364_18135	COG1136	(ABC) transporter
GI364_18145	COG5434	Belongs to the glycosyl hydrolase 28 family
GI364_18145	COG4632	Exopolysaccharide biosynthesis protein
GI364_18155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GI364_18165	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_18175	COG2353	YceI-like domain
GI364_18180	COG1741	Belongs to the pirin family
GI364_18190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_18255	COG3547	Transposase (IS116 IS110 IS902 family)
GI364_18280	COG1335	isochorismatase
GI364_18340	COG1162	GTPase activity
GI364_18360	COG2814	Major facilitator Superfamily
GI364_18365	COG1309	transcriptional regulator
GI364_18375	COG0572	uridine kinase
GI364_18390	COG1012	belongs to the aldehyde dehydrogenase family
GI364_18395	COG1132	(ABC) transporter
GI364_18400	COG1132	(ABC) transporter
GI364_18415	COG1691	(AIR) carboxylase
GI364_18420	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GI364_18425	COG1606	tRNA processing
GI364_18435	COG0667	Aldo Keto reductase
GI364_18440	COG0667	Aldo Keto reductase
GI364_18445	COG1733	regulation of RNA biosynthetic process
GI364_18455	COG1139	Iron-sulfur cluster binding protein
GI364_18465	COG2186	Transcriptional regulator
GI364_18470	COG0277	FAD linked oxidase domain protein
GI364_18475	COG0247	lactate metabolic process
GI364_18480	COG0277	FAD linked oxidase domain protein
GI364_18485	COG1131	(ABC) transporter
GI364_18540	COG0747	negative chemotaxis
GI364_18545	COG2207	Transcriptional regulator
GI364_18550	COG4608	Belongs to the ABC transporter superfamily
GI364_18560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_18565	COG0601	transmembrane transport
GI364_18575	COG1070	Carbohydrate kinase
GI364_18590	COG1063	alcohol dehydrogenase
GI364_18595	COG1175	transmembrane transport
GI364_18600	COG1175	transmembrane transport
GI364_18605	COG1653	transport
GI364_18610	COG1349	DNA-binding transcription factor activity
GI364_18615	COG1070	Carbohydrate kinase
GI364_18620	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_18640	COG0673	inositol 2-dehydrogenase activity
GI364_18645	COG0395	ABC-type sugar transport system, permease component
GI364_18650	COG1175	transmembrane transport
GI364_18655	COG2182	Extracellular solute-binding protein
GI364_18660	COG1312	Catalyzes the dehydration of D-mannonate
GI364_18670	COG1802	Transcriptional regulator
GI364_18680	COG0840	transmembrane signaling receptor activity
GI364_18695	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_18705	COG1349	DNA-binding transcription factor activity
GI364_18710	COG1070	Carbohydrate kinase
GI364_18715	COG1904	glucuronate isomerase
GI364_18720	COG0800	Aldolase
GI364_18725	COG2721	sulfolactate sulfo-lyase activity
GI364_18730	COG1609	Transcriptional regulator
GI364_18735	COG0246	Mannitol dehydrogenase
GI364_18740	COG1349	DNA-binding transcription factor activity
GI364_18755	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GI364_18760	COG1940	carbohydrate kinase activity
GI364_18765	COG0395	ABC-type sugar transport system, permease component
GI364_18770	COG1175	transmembrane transport
GI364_18780	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GI364_18785	COG1085	galactose-1-phosphate uridylyltransferase
GI364_18790	COG1349	DNA-binding transcription factor activity
GI364_18800	COG2723	6-phospho-beta-galactosidase activity
GI364_18810	COG1940	carbohydrate kinase activity
GI364_18825	COG2084	Dehydrogenase
GI364_18835	COG0395	ABC-type sugar transport system, permease component
GI364_18840	COG1175	transmembrane transport
GI364_18845	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_18855	COG3250	beta-galactosidase activity
GI364_18910	COG0395	ABC-type sugar transport system, permease component
GI364_18915	COG1175	transmembrane transport
GI364_18940	COG1850	ribulose-bisphosphate carboxylase activity
GI364_18955	COG3408	Glycogen debranching enzyme
GI364_18960	COG3408	Glycogen debranching enzyme
GI364_18970	COG1349	DNA-binding transcription factor activity
GI364_18975	COG4952	isomerase
GI364_18980	COG3347	Dehydrogenase
GI364_18980	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_18985	COG1070	Carbohydrate kinase
GI364_18990	COG0667	Aldo Keto reductase
GI364_18995	COG2084	Dehydrogenase
GI364_19000	COG0352	thiamine-phosphate diphosphorylase activity
GI364_19005	COG4948	Mandelate Racemase Muconate Lactonizing
GI364_19010	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GI364_19015	COG2271	Major facilitator Superfamily
GI364_19025	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI364_19035	COG2376	Dihydroxyacetone kinase
GI364_19040	COG1461	Dihydroxyacetone kinase
GI364_19045	COG0149	triose-phosphate isomerase activity
GI364_19050	COG1349	DNA-binding transcription factor activity
GI364_19065	COG4221	oxidoreductase activity
GI364_19070	COG0371	Dehydrogenase
GI364_19080	COG0395	ABC-type sugar transport system, permease component
GI364_19100	COG0395	ABC-type sugar transport system, permease component
GI364_19105	COG1175	transmembrane transport
GI364_19120	COG1609	Transcriptional regulator
GI364_19140	COG0395	ABC-type sugar transport system, permease component
GI364_19145	COG1175	transmembrane transport
GI364_19150	COG1609	Transcriptional regulator
GI364_19155	COG3344	reverse transcriptase
GI364_19170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI364_19210	COG0741	lytic transglycosylase activity
GI364_19215	COG0237	dephospho-CoA kinase activity
GI364_19220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GI364_19225	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GI364_19225	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GI364_19230	COG0039	L-malate dehydrogenase activity
GI364_19235	COG0538	isocitrate dehydrogenase activity
GI364_19240	COG2205	protein histidine kinase activity
GI364_19245	COG0745	RESPONSE REGULATOR receiver
GI364_19250	COG0180	Tryptophanyl-tRNA synthetase
GI364_19260	COG0205	6-phosphofructokinase activity
GI364_19265	COG0825	malonyl-CoA metabolic process
GI364_19270	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GI364_19280	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GI364_19285	COG0587	DNA-directed DNA polymerase activity
GI364_19290	COG4109	DRTGG domain
GI364_19310	COG0352	thiamine-phosphate diphosphorylase activity
GI364_19315	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GI364_19320	COG0351	phosphomethylpyrimidine kinase
GI364_19325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GI364_19330	COG1396	sequence-specific DNA binding
GI364_19345	COG1438	arginine binding
GI364_19355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GI364_19370	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GI364_19375	COG3679	Belongs to the UPF0342 family
GI364_19380	COG2346	COG2346, Truncated hemoglobins
GI364_19390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GI364_19395	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GI364_19405	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GI364_19410	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GI364_19410	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GI364_19420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GI364_19420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GI364_19425	COG1045	serine acetyltransferase
GI364_19430	COG1914	H( )-stimulated, divalent metal cation uptake system
GI364_19435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GI364_19450	COG0475	glutathione-regulated potassium exporter activity
GI364_19450	COG0569	domain protein
GI364_19455	COG4496	protein, YerC YecD
GI364_19475	COG0785	Cytochrome C biogenesis protein
GI364_19480	COG5002	protein histidine kinase activity
GI364_19505	COG0735	belongs to the Fur family
GI364_19515	COG1121	(ABC) transporter
GI364_19525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GI364_19535	COG1234	tRNA 3'-trailer cleavage
GI364_19550	COG4152	abc transporter atp-binding protein
GI364_19585	COG2814	Major facilitator Superfamily
GI364_19595	COG0535	radical SAM domain protein
GI364_19600	COG1533	DNA photolyase activity
GI364_19605	COG2814	Major facilitator Superfamily
GI364_19610	COG2226	methyltransferase
GI364_19705	COG1396	sequence-specific DNA binding
GI364_19745	COG0582	viral genome integration into host DNA
GI364_19760	COG1611	Belongs to the LOG family
GI364_19765	COG1506	peptidase
GI364_19770	COG0546	phosphoglycolate phosphatase activity
GI364_19800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_19810	COG0653	protein targeting
GI364_19830	COG0463	Glycosyl transferase, family 2
GI364_19830	COG0457	Tetratricopeptide repeat
GI364_19855	COG4786	Flagellar basal body rod
GI364_19855	COG1256	bacterial-type flagellum assembly
GI364_19885	COG1607	acyl-coa hydrolase
GI364_19890	COG1040	competence protein
GI364_19895	COG1307	EDD domain protein, DegV family
GI364_19900	COG5002	protein histidine kinase activity
GI364_19905	COG0745	RESPONSE REGULATOR receiver
GI364_19920	COG2197	response regulator
GI364_19930	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GI364_19950	COG1278	Cold shock
GI364_19955	COG2814	Major facilitator Superfamily
GI364_19965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GI364_19970	COG0315	cyclic pyranopterin monophosphate synthase activity
GI364_19970	COG0521	Mo-molybdopterin cofactor biosynthetic process
GI364_19985	COG1122	ATPase activity
GI364_19990	COG1122	ATPase activity
GI364_19995	COG0697	spore germination
GI364_20000	COG3321	synthase
GI364_20000	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_20000	COG0604	alcohol dehydrogenase
GI364_20005	COG1609	Transcriptional regulator
GI364_20010	COG1070	Carbohydrate kinase
GI364_20015	COG2271	Major facilitator Superfamily
GI364_20020	COG3547	Transposase (IS116 IS110 IS902 family)
GI364_20025	COG2363	Small membrane protein
GI364_20030	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GI364_20040	COG1914	H( )-stimulated, divalent metal cation uptake system
GI364_20050	COG0561	phosphatase activity
GI364_20090	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GI364_20095	COG1181	Belongs to the D-alanine--D-alanine ligase family
GI364_20100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GI364_20120	COG0704	Plays a role in the regulation of phosphate uptake
GI364_20125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GI364_20130	COG2814	Major facilitator Superfamily
GI364_20140	COG1595	DNA-templated transcription, initiation
GI364_20145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GI364_20145	COG3153	acetyltransferase
GI364_20150	COG1597	lipid kinase activity
GI364_20180	COG1012	belongs to the aldehyde dehydrogenase family
GI364_20185	COG0187	DNA topoisomerase II activity
GI364_20190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GI364_20200	COG0579	oxidoreductase
GI364_20205	COG0534	Mate efflux family protein
GI364_20210	COG0583	DNA-binding transcription factor activity
GI364_20215	COG0028	Belongs to the TPP enzyme family
GI364_20220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GI364_20240	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GI364_20245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GI364_20270	COG0395	ABC-type sugar transport system, permease component
GI364_20285	COG3328	transposase activity
GI364_20290	COG1011	Hydrolase
GI364_20300	COG0747	negative chemotaxis
GI364_20310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_20315	COG0444	Belongs to the ABC transporter superfamily
GI364_20320	COG4608	Belongs to the ABC transporter superfamily
GI364_20345	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GI364_20350	COG1122	ATPase activity
GI364_20380	COG1609	Transcriptional regulator
GI364_20400	COG2160	L-arabinose isomerase activity
GI364_20410	COG1252	NADH dehydrogenase
GI364_20425	COG0659	secondary active sulfate transmembrane transporter activity
GI364_20430	COG1472	Belongs to the glycosyl hydrolase 3 family
GI364_20455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GI364_20465	COG1278	Cold shock
GI364_20475	COG3239	Fatty acid desaturase
GI364_20480	COG0667	Aldo Keto reductase
GI364_20485	COG0656	L-ascorbic acid biosynthetic process
GI364_20490	COG2207	Transcriptional regulator
GI364_20495	COG4608	Belongs to the ABC transporter superfamily
GI364_20500	COG0444	Belongs to the ABC transporter superfamily
GI364_20505	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GI364_20510	COG0601	transmembrane transport
GI364_20515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_20520	COG4946	Tricorn protease homolog
GI364_20520	COG1506	peptidase
GI364_20520	COG0823	Involved in the tonB-independent uptake of proteins
GI364_20525	COG0747	negative chemotaxis
GI364_20570	COG0189	ligase activity
GI364_20580	COG0488	(ABC) transporter
GI364_20590	COG1331	Highly conserved protein containing a thioredoxin domain
GI364_20595	COG0583	DNA-binding transcription factor activity
GI364_20630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GI364_20635	COG0673	inositol 2-dehydrogenase activity
GI364_20640	COG1083	cytidylyl-transferase
GI364_20645	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_20655	COG2089	acid synthase
GI364_20660	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GI364_20665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GI364_20675	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GI364_20680	COG0116	Belongs to the methyltransferase superfamily
GI364_20690	COG0492	ferredoxin-NADP+ reductase activity
GI364_20695	COG4106	trans-aconitate 2-methyltransferase activity
GI364_20700	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GI364_20705	COG0604	alcohol dehydrogenase
GI364_20715	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GI364_20730	COG1278	Cold shock
GI364_20740	COG1131	(ABC) transporter
GI364_20745	COG1597	lipid kinase activity
GI364_20750	COG4990	cell redox homeostasis
GI364_20755	COG2197	response regulator
GI364_20760	COG4585	Histidine kinase
GI364_20765	COG0446	pyridine nucleotide-disulphide oxidoreductase
GI364_20770	COG1271	oxidase subunit
GI364_20775	COG1294	oxidase, subunit
GI364_20780	COG1022	Amp-dependent synthetase and ligase
GI364_20805	COG0723	plastoquinol--plastocyanin reductase activity
GI364_20805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GI364_20810	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GI364_20825	COG1725	Transcriptional regulator
GI364_20850	COG3384	dioxygenase
GI364_20855	COG0531	amino acid
GI364_20880	COG2226	methyltransferase
GI364_20885	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_20910	COG0640	Transcriptional regulator
GI364_20970	COG0789	Transcriptional regulator
GI364_20980	COG1733	regulation of RNA biosynthetic process
GI364_20990	COG0789	Transcriptional regulator
GI364_21000	COG0431	NADPH-dependent FMN reductase
GI364_21015	COG0596	Alpha beta hydrolase
GI364_21025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_21035	COG3973	AAA domain
GI364_21050	COG0400	carboxylic ester hydrolase activity
GI364_21055	COG0346	lactoylglutathione lyase activity
GI364_21060	COG1733	regulation of RNA biosynthetic process
GI364_21065	COG2890	protein-(glutamine-N5) methyltransferase activity
GI364_21070	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GI364_21090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_21100	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GI364_21110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_21135	COG0598	Magnesium transport protein CorA
GI364_21180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_21200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI364_21350	COG0456	acetyltransferase
GI364_21360	COG0464	growth
GI364_21365	COG1404	Belongs to the peptidase S8 family
GI364_21395	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GI364_21400	COG0363	glucosamine-6-phosphate deaminase activity
GI364_21405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GI364_21410	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GI364_21420	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_21435	COG0204	Acyl-transferase
GI364_21440	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GI364_21440	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GI364_21445	COG1309	transcriptional regulator
GI364_21450	COG0517	IMP dehydrogenase activity
GI364_21465	COG4608	Belongs to the ABC transporter superfamily
GI364_21470	COG0444	Belongs to the ABC transporter superfamily
GI364_21475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_21480	COG0601	transmembrane transport
GI364_21485	COG0747	negative chemotaxis
GI364_21490	COG1737	Transcriptional regulator
GI364_21500	COG0673	inositol 2-dehydrogenase activity
GI364_21520	COG4555	ABC transporter
GI364_21530	COG1937	Protein conserved in bacteria
GI364_21560	COG2197	response regulator
GI364_21575	COG1937	Protein conserved in bacteria
GI364_21585	COG0670	Belongs to the BI1 family
GI364_21595	COG4584	PFAM Integrase catalytic
GI364_21600	COG4974	Belongs to the 'phage' integrase family
GI364_21605	COG4974	Belongs to the 'phage' integrase family
GI364_21610	COG4974	Belongs to the 'phage' integrase family
GI364_21615	COG4584	PFAM Integrase catalytic
GI364_21620	COG1484	DNA-dependent DNA replication
GI364_21630	COG1733	regulation of RNA biosynthetic process
GI364_21675	COG1842	Phage shock protein A
GI364_21685	COG5002	protein histidine kinase activity
GI364_21690	COG0745	RESPONSE REGULATOR receiver
GI364_21705	COG0785	Cytochrome C biogenesis protein
GI364_21745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI364_21765	COG1937	Protein conserved in bacteria
GI364_21785	COG4990	cell redox homeostasis
GI364_21795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GI364_21805	COG2814	Major facilitator Superfamily
GI364_21815	COG0425	Belongs to the sulfur carrier protein TusA family
GI364_21815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_21830	COG4974	Belongs to the 'phage' integrase family
GI364_21850	COG0697	spore germination
GI364_21880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GI364_21885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GI364_21895	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GI364_21915	COG0726	polysaccharide deacetylase
GI364_21930	COG0489	protein tyrosine kinase activity
GI364_21940	COG0860	N-Acetylmuramoyl-L-alanine amidase
GI364_21945	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GI364_21950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GI364_21955	COG0101	tRNA pseudouridine synthase activity
GI364_21960	COG0203	ribosomal protein L17
GI364_21965	COG0202	RNA polymerase activity
GI364_21970	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GI364_21975	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GI364_21980	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GI364_21985	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GI364_21990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GI364_22000	COG0563	adenylate kinase activity
GI364_22005	COG0201	protein transport
GI364_22010	COG0200	Binds to the 23S rRNA
GI364_22020	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GI364_22025	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GI364_22030	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GI364_22035	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GI364_22040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GI364_22045	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GI364_22055	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GI364_22060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GI364_22065	COG0255	Belongs to the universal ribosomal protein uL29 family
GI364_22070	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GI364_22080	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GI364_22085	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GI364_22090	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GI364_22095	COG0089	rRNA binding
GI364_22100	COG0088	Forms part of the polypeptide exit tunnel
GI364_22105	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GI364_22110	COG0051	transcription antitermination factor activity, RNA binding
GI364_22115	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GI364_22120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GI364_22125	COG0049	tRNA binding
GI364_22130	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GI364_22135	COG1358	cellular component organization or biogenesis
GI364_22140	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GI364_22145	COG0085	RNA polymerase activity
GI364_22150	COG2813	Specifically methylates the guanine in position
GI364_22155	COG0222	ribosome binding
GI364_22160	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GI364_22165	COG0081	regulation of translation
GI364_22175	COG0250	Participates in transcription elongation, termination and antitermination
GI364_22185	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GI364_22200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GI364_22205	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GI364_22210	COG0215	cysteine-tRNA ligase activity
GI364_22215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GI364_22220	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GI364_22225	COG4956	integral membrane protein (PIN domain superfamily)
GI364_22230	COG1183	phosphatidylcholine synthase activity
GI364_22235	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GI364_22240	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GI364_22245	COG0542	response to heat
GI364_22250	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GI364_22255	COG3880	PFAM UvrB UvrC protein
GI364_22265	COG1309	transcriptional regulator
GI364_22320	COG0151	Belongs to the GarS family
GI364_22330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GI364_22335	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GI364_22340	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GI364_22345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GI364_22350	COG0047	phosphoribosylformylglycinamidine synthase activity
GI364_22355	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GI364_22360	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GI364_22365	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GI364_22390	COG0500	methyltransferase
GI364_22405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_22425	COG0842	Transport permease protein
GI364_22435	COG1131	(ABC) transporter
GI364_22440	COG2197	response regulator
GI364_22445	COG4585	Histidine kinase
GI364_22450	COG2252	PERMEase
GI364_22460	COG1305	Transglutaminase-like
GI364_22470	COG0714	Associated with various cellular activities
GI364_22480	COG0459	protein refolding
GI364_22485	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GI364_22490	COG0805	protein transport
GI364_22495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GI364_22515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GI364_22520	COG0488	(ABC) transporter
GI364_22525	COG2113	Glycine betaine
GI364_22535	COG0517	IMP dehydrogenase activity
GI364_22535	COG4175	Glycine betaine
GI364_22540	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GI364_22545	COG0456	acetyltransferase
GI364_22550	COG1214	PFAM Peptidase M22, glycoprotease
GI364_22555	COG0802	atpase or kinase
GI364_22560	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GI364_22565	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GI364_22590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GI364_22595	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GI364_22600	COG2337	Toxic component of a toxin-antitoxin (TA) module
GI364_22605	COG0864	Transcriptional regulator
GI364_22610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GI364_22620	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GI364_22625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GI364_22625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GI364_22630	COG0736	holo-[acyl-carrier-protein] synthase activity
GI364_22650	COG1506	peptidase
GI364_22655	COG0024	Methionine aminopeptidase
GI364_22685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GI364_22695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GI364_22705	COG4464	protein tyrosine phosphatase activity
GI364_22715	COG0772	Belongs to the SEDS family
GI364_22725	COG1968	undecaprenyl-diphosphatase activity
GI364_22740	COG1609	Transcriptional regulator
GI364_22745	COG3833	ABC-type maltose transport systems, permease component
GI364_22750	COG1175	transmembrane transport
GI364_22755	COG2182	Extracellular solute-binding protein
GI364_22770	COG0531	amino acid
GI364_22775	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GI364_22780	COG1846	Transcriptional regulator
GI364_22785	COG0477	Major facilitator Superfamily
GI364_22795	COG1802	Transcriptional regulator
GI364_22810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GI364_22815	COG2059	Chromate
GI364_22825	COG2059	Chromate
GI364_22850	COG1012	belongs to the aldehyde dehydrogenase family
GI364_22875	COG1595	DNA-templated transcription, initiation
GI364_22885	COG0668	transmembrane transport
GI364_22890	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GI364_22895	COG4988	ABC transporter
GI364_22900	COG2113	Glycine betaine
GI364_22925	COG5001	Diguanylate cyclase
GI364_22925	COG3300	MHYT domain
GI364_22930	COG1316	TRANSCRIPTIONal
GI364_22945	COG2814	Major facilitator Superfamily
GI364_22960	COG1592	Rubrerythrin
GI364_23045	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GI364_23065	COG2226	methyltransferase
GI364_23090	COG1136	(ABC) transporter
GI364_23090	COG0577	efflux transmembrane transporter activity
GI364_23130	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GI364_23165	COG0494	nUDIX hydrolase
GI364_23185	COG1609	Transcriptional regulator
GI364_23190	COG1653	transport
GI364_23205	COG0366	Alpha amylase catalytic
GI364_23220	COG1984	allophanate hydrolase subunit 2
GI364_23230	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GI364_23235	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GI364_23240	COG0489	protein tyrosine kinase activity
GI364_23245	COG3944	biosynthesis protein
GI364_23265	COG0562	UDP-galactopyranose mutase
GI364_23270	COG2244	polysaccharide biosynthetic process
GI364_23280	COG0438	transferase activity, transferring glycosyl groups
GI364_23300	COG0438	transferase activity, transferring glycosyl groups
GI364_23305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GI364_23310	COG1739	Uncharacterized protein family UPF0029
GI364_23315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GI364_23370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GI364_23375	COG4786	Flagellar basal body rod
GI364_23380	COG4786	Flagellar basal body rod
GI364_23385	COG1077	Cell shape determining protein MreB Mrl
GI364_23390	COG1609	Transcriptional regulator
GI364_23395	COG0739	heme binding
GI364_23400	COG2385	sporulation resulting in formation of a cellular spore
GI364_23405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GI364_23435	COG1007	ATP synthesis coupled electron transport
GI364_23440	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GI364_23445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GI364_23450	COG0713	ATP synthesis coupled electron transport
GI364_23455	COG0839	Belongs to the complex I subunit 6 family
GI364_23465	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GI364_23470	COG0649	NAD binding
GI364_23475	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GI364_23480	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GI364_23485	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GI364_23490	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GI364_23495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GI364_23500	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GI364_23505	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GI364_23510	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GI364_23515	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GI364_23520	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GI364_23525	COG0356	it plays a direct role in the translocation of protons across the membrane
GI364_23545	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GI364_23550	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GI364_23555	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GI364_23565	COG0004	ammonium transporteR
GI364_23595	COG1595	DNA-templated transcription, initiation
GI364_23615	COG1683	Conserved Protein
GI364_23625	COG0477	Major facilitator Superfamily
GI364_23635	COG0702	epimerase
GI364_23640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GI364_23645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GI364_23650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GI364_23660	COG0698	ribose 5-phosphate isomerase
GI364_23665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GI364_23670	COG1971	Probably functions as a manganese efflux pump
GI364_23680	COG0009	L-threonylcarbamoyladenylate synthase
GI364_23690	COG0436	Aminotransferase
GI364_23700	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GI364_23705	COG0254	rRNA binding
GI364_23710	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GI364_23715	COG1494	fructose-1,6-bisphosphatase
GI364_23725	COG0436	Aminotransferase
GI364_23730	COG1473	amidohydrolase
GI364_23735	COG2171	N-acyltransferase activity
GI364_23745	COG3246	L-lysine catabolic process to acetate
GI364_23750	COG1607	acyl-coa hydrolase
GI364_23755	COG2204	response regulator
GI364_23760	COG0504	CTP synthase activity
GI364_23765	COG3343	RNA polymerase activity
GI364_23770	COG1703	isobutyryl-CoA mutase activity
GI364_23775	COG1960	acyl-CoA dehydrogenase activity
GI364_23780	COG1960	acyl-CoA dehydrogenase activity
GI364_23785	COG1024	Enoyl-CoA hydratase
GI364_23790	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI364_23795	COG0183	Belongs to the thiolase family
GI364_23800	COG2181	nitrate reductase activity
GI364_23800	COG0247	lactate metabolic process
GI364_23855	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI364_23915	COG0596	Alpha beta hydrolase
GI364_23920	COG2249	NAD(P)H dehydrogenase (quinone) activity
GI364_23955	COG0508	dehydrogenase complex catalyzes the overall conversion of
GI364_23960	COG0567	Dehydrogenase, E1 component
GI364_23970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GI364_23985	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_23990	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GI364_23995	COG1131	(ABC) transporter
GI364_24020	COG1121	(ABC) transporter
GI364_24040	COG0243	molybdopterin cofactor binding
GI364_24050	COG5012	cobalamin binding
GI364_24055	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GI364_24070	COG1509	lysine 2,3-aminomutase activity
GI364_24075	COG0604	alcohol dehydrogenase
GI364_24100	COG0010	Belongs to the arginase family
GI364_24105	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GI364_24110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GI364_24125	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_24140	COG2843	Capsule synthesis protein
GI364_24145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GI364_24150	COG0572	uridine kinase
GI364_24160	COG1033	growth of symbiont in host cell
GI364_24160	COG2409	Drug exporters of the RND superfamily
GI364_24180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GI364_24185	COG1725	Transcriptional regulator
GI364_24190	COG1131	(ABC) transporter
GI364_24210	COG5002	protein histidine kinase activity
GI364_24215	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_24300	COG1484	DNA-dependent DNA replication
GI364_24310	COG4584	PFAM Integrase catalytic
GI364_24320	COG0010	Belongs to the arginase family
GI364_24330	COG0076	glutamate decarboxylase activity
GI364_24360	COG1063	alcohol dehydrogenase
GI364_24370	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GI364_24375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI364_24380	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GI364_24395	COG5002	protein histidine kinase activity
GI364_24400	COG0745	RESPONSE REGULATOR receiver
GI364_24410	COG0305	Participates in initiation and elongation during chromosome replication
GI364_24435	COG0629	single-stranded DNA binding
GI364_24440	COG0360	Binds together with S18 to 16S ribosomal RNA
GI364_24445	COG0012	GTP binding
GI364_24455	COG4481	Protein conserved in bacteria
GI364_24475	COG1811	Na channel or pump
GI364_24480	COG1475	DNA binding
GI364_24485	COG1192	Involved in chromosome partitioning
GI364_24490	COG1475	DNA binding
GI364_24500	COG0445	tRNA wobble uridine modification
GI364_24510	COG1847	R3H domain protein
GI364_24515	COG0706	membrane insertase activity
GI364_24520	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GI364_24525	COG0594	ribonuclease P activity
GI364_24530	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GI364_24535	COG1192	Involved in chromosome partitioning
GI364_24560	COG1484	DNA-dependent DNA replication
GI364_24585	COG0582	viral genome integration into host DNA
GI364_24590	COG1742	UPF0060 membrane protein
GI364_24610	COG0640	Transcriptional regulator
GI364_24615	COG1230	cation diffusion facilitator family transporter
GI364_24680	COG0640	Transcriptional regulator
GI364_24685	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GI364_24690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GI364_24695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GI364_24800	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GI364_24905	COG3645	SOS response
GI364_24905	COG3646	Phage regulatory protein
GI364_24950	COG4974	Belongs to the 'phage' integrase family
GI364_24955	COG0534	Mate efflux family protein
GI364_24980	COG0697	spore germination
GI364_25000	COG4974	Belongs to the 'phage' integrase family
GI364_25025	COG0531	amino acid