locus-tag	class	description
FY534_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY534_00010	COG0592	DNA-directed DNA polymerase activity
FY534_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY534_00030	COG0187	DNA topoisomerase II activity
FY534_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY534_00055	COG0516	GMP reductase activity
FY534_00055	COG0517	IMP dehydrogenase activity
FY534_00060	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FY534_00065	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FY534_00085	COG0582	viral genome integration into host DNA
FY534_00125	COG0556	nucleotide-excision repair
FY534_00145	COG1403	HNH endonuclease
FY534_00155	COG0651	ATP synthesis coupled electron transport
FY534_00160	COG0650	Formate hydrogenlyase subunit 4
FY534_00170	COG0651	ATP synthesis coupled electron transport
FY534_00175	COG3261	NADH dehydrogenase
FY534_00175	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FY534_00185	COG3260	NADH ubiquinone oxidoreductase 20
FY534_00200	COG0583	DNA-binding transcription factor activity
FY534_00230	COG1960	acyl-CoA dehydrogenase activity
FY534_00245	COG2267	carboxylic ester hydrolase activity
FY534_00250	COG4187	Peptidase family M20/M25/M40
FY534_00255	COG0667	Aldo Keto reductase
FY534_00265	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY534_00275	COG2267	carboxylic ester hydrolase activity
FY534_00280	COG2124	cytochrome p450
FY534_00285	COG0166	Belongs to the GPI family
FY534_00290	COG1940	carbohydrate kinase activity
FY534_00305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY534_00325	COG0735	belongs to the Fur family
FY534_00335	COG1121	(ABC) transporter
FY534_00350	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FY534_00365	COG0395	ABC-type sugar transport system, permease component
FY534_00370	COG3250	beta-galactosidase activity
FY534_00375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY534_00380	COG0657	acetylesterase activity
FY534_00385	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FY534_00390	COG1850	ribulose-bisphosphate carboxylase activity
FY534_00395	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FY534_00400	COG0235	Class ii aldolase
FY534_00405	COG0367	asparagine synthase
FY534_00420	COG0590	tRNA wobble adenosine to inosine editing
FY534_00450	COG3852	Histidine kinase
FY534_00455	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY534_00460	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY534_00465	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY534_00480	COG2244	polysaccharide biosynthetic process
FY534_00490	COG1982	Orn Lys Arg decarboxylase major
FY534_00495	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY534_00500	COG3870	Protein conserved in bacteria
FY534_00505	COG0470	DNA polymerase III
FY534_00510	COG1774	PSP1 C-terminal conserved region
FY534_00515	COG4467	Involved in initiation control of chromosome replication
FY534_00520	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY534_00525	COG2002	toxin-antitoxin pair type II binding
FY534_00540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY534_00560	COG0084	hydrolase, TatD family'
FY534_00565	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FY534_00570	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY534_00585	COG4466	Protein conserved in bacteria
FY534_00595	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY534_00595	COG0189	ligase activity
FY534_00600	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY534_00605	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY534_00610	COG0251	oxidation-reduction process
FY534_00615	COG2088	sporulation resulting in formation of a cellular spore
FY534_00620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY534_00630	COG0193	aminoacyl-tRNA hydrolase activity
FY534_00640	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY534_00645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY534_00650	COG2002	toxin-antitoxin pair type II binding
FY534_00655	COG2244	polysaccharide biosynthetic process
FY534_00660	COG3956	TIGRFAM MazG family protein
FY534_00670	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FY534_00690	COG1098	S1 RNA binding domain
FY534_00695	COG3344	reverse transcriptase
FY534_00710	COG2131	deaminase
FY534_00715	COG2208	phosphoserine phosphatase activity
FY534_00720	COG2304	oxidoreductase activity
FY534_00730	COG0037	tRNA processing
FY534_00735	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FY534_00740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY534_00745	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FY534_00750	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FY534_00755	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY534_00760	COG1396	sequence-specific DNA binding
FY534_00765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY534_00770	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY534_00810	COG0243	molybdopterin cofactor binding
FY534_00815	COG2211	Major facilitator Superfamily
FY534_00845	COG2323	membrane
FY534_00850	COG1960	acyl-CoA dehydrogenase activity
FY534_00860	COG0477	Major facilitator Superfamily
FY534_00865	COG1846	Transcriptional regulator
FY534_00870	COG0277	FAD linked oxidase domain protein
FY534_00875	COG2814	Major facilitator Superfamily
FY534_00890	COG1802	Transcriptional regulator
FY534_00905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY534_00910	COG0405	Gamma-glutamyltransferase
FY534_00915	COG2059	Chromate
FY534_00920	COG2059	Chromate
FY534_00940	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY534_00955	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FY534_00970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY534_01045	COG1175	transmembrane transport
FY534_01050	COG0395	ABC-type sugar transport system, permease component
FY534_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
FY534_01120	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FY534_01130	COG1214	PFAM Peptidase M22, glycoprotease
FY534_01135	COG0456	acetyltransferase
FY534_01140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY534_01175	COG0697	spore germination
FY534_01180	COG0488	(ABC) transporter
FY534_01185	COG0671	phosphoesterase, PA-phosphatase related
FY534_01195	COG0746	molybdenum cofactor guanylyltransferase activity
FY534_01200	COG1058	Belongs to the CinA family
FY534_01200	COG1546	Belongs to the CinA family
FY534_01215	COG0459	protein refolding
FY534_01220	COG0714	Associated with various cellular activities
FY534_01230	COG1305	Transglutaminase-like
FY534_01235	COG0519	Catalyzes the synthesis of GMP from XMP
FY534_01235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY534_01245	COG0708	Exodeoxyribonuclease III
FY534_01255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY534_01260	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY534_01270	COG0047	phosphoribosylformylglycinamidine synthase activity
FY534_01275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY534_01280	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY534_01285	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY534_01290	COG0138	bifunctional purine biosynthesis protein purh
FY534_01295	COG0151	Belongs to the GarS family
FY534_01300	COG1533	DNA photolyase activity
FY534_01305	COG0745	RESPONSE REGULATOR receiver
FY534_01310	COG2124	cytochrome p450
FY534_01330	COG1309	transcriptional regulator
FY534_01340	COG3880	PFAM UvrB UvrC protein
FY534_01345	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FY534_01350	COG0542	response to heat
FY534_01355	COG3344	reverse transcriptase
FY534_01360	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FY534_01365	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FY534_01370	COG1183	phosphatidylcholine synthase activity
FY534_01375	COG4956	integral membrane protein (PIN domain superfamily)
FY534_01380	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY534_01390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY534_01395	COG0215	cysteine-tRNA ligase activity
FY534_01400	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FY534_01405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY534_01420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY534_01430	COG0250	Participates in transcription elongation, termination and antitermination
FY534_01445	COG0081	regulation of translation
FY534_01450	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY534_01455	COG0222	ribosome binding
FY534_01460	COG2813	Specifically methylates the guanine in position
FY534_01465	COG0085	RNA polymerase activity
FY534_01470	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY534_01480	COG1358	cellular component organization or biogenesis
FY534_01485	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY534_01490	COG0049	tRNA binding
FY534_01495	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY534_01500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY534_01505	COG0051	transcription antitermination factor activity, RNA binding
FY534_01510	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY534_01525	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY534_01530	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY534_01535	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY534_01540	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY534_01545	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY534_01550	COG0255	Belongs to the universal ribosomal protein uL29 family
FY534_01560	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY534_01575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY534_01580	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY534_01585	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY534_01590	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY534_01595	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY534_01600	COG1841	ribosomal large subunit assembly
FY534_01605	COG0200	Binds to the 23S rRNA
FY534_01610	COG0201	protein transport
FY534_01615	COG0563	adenylate kinase activity
FY534_01625	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY534_01630	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY534_01635	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY534_01640	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY534_01645	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY534_01650	COG0202	RNA polymerase activity
FY534_01655	COG0203	ribosomal protein L17
FY534_01660	COG0101	tRNA pseudouridine synthase activity
FY534_01665	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY534_01670	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY534_01675	COG0860	N-Acetylmuramoyl-L-alanine amidase
FY534_01685	COG0489	protein tyrosine kinase activity
FY534_01715	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FY534_01725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY534_01780	COG3586	endonuclease activity
FY534_01790	COG2815	serine threonine protein kinase
FY534_01790	COG0515	serine threonine protein kinase
FY534_01810	COG1073	alpha beta
FY534_01825	COG0456	acetyltransferase
FY534_01825	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FY534_01855	COG1657	PFAM Prenyltransferase squalene oxidase
FY534_01870	COG1279	arginine transmembrane transporter activity
FY534_01885	COG1653	transport
FY534_01890	COG1175	transmembrane transport
FY534_01895	COG3833	ABC-type maltose transport systems, permease component
FY534_01915	COG1607	acyl-coa hydrolase
FY534_01925	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY534_01945	COG4585	Histidine kinase
FY534_01970	COG2318	DinB family
FY534_01975	COG1968	undecaprenyl-diphosphatase activity
FY534_01980	COG2223	nitrite transmembrane transporter activity
FY534_01985	COG0436	Aminotransferase
FY534_01995	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY534_02000	COG1113	amino acid transport
FY534_02005	COG0175	sulfate reduction
FY534_02010	COG2046	Belongs to the sulfate adenylyltransferase family
FY534_02015	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY534_02035	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY534_02050	COG1122	ATPase activity
FY534_02055	COG1268	BioY protein
FY534_02060	COG1802	Transcriptional regulator
FY534_02085	COG0174	glutamine synthetase
FY534_02100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY534_02105	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY534_02110	COG0412	Dienelactone hydrolase
FY534_02115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY534_02120	COG2814	Major facilitator Superfamily
FY534_02125	COG1278	Cold shock
FY534_02140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY534_02165	COG2199	diguanylate cyclase activity
FY534_02165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FY534_02175	COG0745	RESPONSE REGULATOR receiver
FY534_02180	COG5002	protein histidine kinase activity
FY534_02185	COG1307	EDD domain protein, DegV family
FY534_02190	COG1040	competence protein
FY534_02200	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY534_02215	COG1191	sigma factor activity
FY534_02230	COG4786	Flagellar basal body rod
FY534_02230	COG1256	bacterial-type flagellum assembly
FY534_02255	COG0457	Tetratricopeptide repeat
FY534_02255	COG0463	Glycosyl transferase, family 2
FY534_02260	COG1216	Glycosyl transferase, family 2
FY534_02260	COG0438	transferase activity, transferring glycosyl groups
FY534_02265	COG0438	transferase activity, transferring glycosyl groups
FY534_02275	COG0463	Glycosyl transferase, family 2
FY534_02280	COG0463	Glycosyl transferase, family 2
FY534_02280	COG0457	Tetratricopeptide repeat
FY534_02285	COG0653	protein targeting
FY534_02290	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FY534_02320	COG2884	Cell division ATP-binding protein ftsE
FY534_02325	COG2177	Part of the ABC transporter FtsEX involved in
FY534_02335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY534_02340	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY534_02350	COG0556	nucleotide-excision repair
FY534_02355	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY534_02365	COG0018	arginyl-trna synthetase
FY534_02375	COG1660	Displays ATPase and GTPase activities
FY534_02380	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FY534_02385	COG1481	regulation of sporulation
FY534_02395	COG2197	response regulator
FY534_02410	COG1131	(ABC) transporter
FY534_02420	COG1335	isochorismatase
FY534_02435	COG0670	Belongs to the BI1 family
FY534_02440	COG0495	leucyl-tRNA aminoacylation
FY534_02455	COG0813	purine-nucleoside phosphorylase activity
FY534_02465	COG0628	permease
FY534_02480	COG0318	PFAM AMP-dependent synthetase and ligase
FY534_02490	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FY534_02500	COG0697	spore germination
FY534_02530	COG0538	isocitrate dehydrogenase activity
FY534_02575	COG2766	serine protein kinase
FY534_02580	COG2718	Belongs to the UPF0229 family
FY534_02585	COG2719	SpoVR family
FY534_02615	COG0395	ABC-type sugar transport system, permease component
FY534_02620	COG1414	Transcriptional regulator
FY534_02625	COG1960	acyl-CoA dehydrogenase activity
FY534_02645	COG0668	transmembrane transport
FY534_02675	COG0004	ammonium transporteR
FY534_02690	COG2176	DNA-directed DNA polymerase activity
FY534_02700	COG1686	Belongs to the peptidase S11 family
FY534_02705	COG1132	(ABC) transporter
FY534_02710	COG1132	(ABC) transporter
FY534_02750	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_02785	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY534_02790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY534_02795	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY534_02800	COG0154	amidase activity
FY534_02805	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY534_02810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY534_02815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY534_02820	COG0798	PFAM Bile acid sodium symporter
FY534_02825	COG0640	Transcriptional regulator
FY534_02830	COG1012	belongs to the aldehyde dehydrogenase family
FY534_02840	COG0681	Belongs to the peptidase S26 family
FY534_02880	COG0789	Transcriptional regulator
FY534_02885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY534_02895	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_02905	COG1082	Xylose isomerase domain protein TIM barrel
FY534_02915	COG0673	inositol 2-dehydrogenase activity
FY534_02920	COG0673	inositol 2-dehydrogenase activity
FY534_02925	COG0077	Prephenate dehydratase
FY534_02925	COG1605	Chorismate mutase
FY534_02930	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FY534_02935	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY534_02955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FY534_02965	COG0318	PFAM AMP-dependent synthetase and ligase
FY534_02975	COG1960	acyl-CoA dehydrogenase activity
FY534_02980	COG1024	Enoyl-CoA hydratase
FY534_03000	COG2197	response regulator
FY534_03020	COG1609	Transcriptional regulator
FY534_03025	COG0747	negative chemotaxis
FY534_03045	COG4608	Belongs to the ABC transporter superfamily
FY534_03055	COG2723	6-phospho-beta-galactosidase activity
FY534_03060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY534_03065	COG2124	cytochrome p450
FY534_03105	COG0745	RESPONSE REGULATOR receiver
FY534_03110	COG2205	protein histidine kinase activity
FY534_03120	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY534_03125	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY534_03135	COG2205	protein histidine kinase activity
FY534_03140	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY534_03145	COG1595	DNA-templated transcription, initiation
FY534_03160	COG0671	phosphoesterase, PA-phosphatase related
FY534_03170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY534_03180	COG3844	kynureninase activity
FY534_03210	COG0277	FAD linked oxidase domain protein
FY534_03245	COG1937	Protein conserved in bacteria
FY534_03250	COG2217	Heavy metal translocating P-type atpase
FY534_03260	COG0351	phosphomethylpyrimidine kinase
FY534_03265	COG0352	thiamine-phosphate diphosphorylase activity
FY534_03270	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_03285	COG2095	MarC family integral membrane protein
FY534_03290	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_03295	COG3848	Pyruvate phosphate dikinase
FY534_03295	COG0574	Belongs to the PEP-utilizing enzyme family
FY534_03300	COG3848	Pyruvate phosphate dikinase
FY534_03300	COG0574	Belongs to the PEP-utilizing enzyme family
FY534_03305	COG2814	Major facilitator Superfamily
FY534_03310	COG1175	transmembrane transport
FY534_03315	COG0395	ABC-type sugar transport system, permease component
FY534_03330	COG1216	Glycosyl transferase, family 2
FY534_03335	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY534_03345	COG2124	cytochrome p450
FY534_03355	COG1562	ergosterol biosynthetic process
FY534_03360	COG0142	geranyltranstransferase activity
FY534_03375	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_03380	COG0640	Transcriptional regulator
FY534_03385	COG0500	methyltransferase
FY534_03425	COG4974	Belongs to the 'phage' integrase family
FY534_03430	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FY534_03440	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FY534_03470	COG1388	LysM domain
FY534_03470	COG3858	chitin binding
FY534_03475	COG0346	lactoylglutathione lyase activity
FY534_03480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY534_03490	COG5577	PFAM Coat F domain
FY534_03495	COG0019	diaminopimelate decarboxylase activity
FY534_03530	COG1164	Oligoendopeptidase f
FY534_03535	COG3852	Histidine kinase
FY534_03545	COG0697	spore germination
FY534_03550	COG0126	phosphoglycerate kinase activity
FY534_03560	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY534_03565	COG0148	phosphopyruvate hydratase activity
FY534_03570	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY534_03575	COG0557	exoribonuclease II activity
FY534_03580	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY534_03595	COG0501	Belongs to the peptidase M48B family
FY534_03610	COG3239	Fatty acid desaturase
FY534_03625	COG1648	precorrin-2 dehydrogenase activity
FY534_03625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY534_03645	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY534_03675	COG1492	cobalamin metabolic process
FY534_03680	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY534_03690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY534_03695	COG2210	Belongs to the sulfur carrier protein TusA family
FY534_03700	COG0425	Belongs to the sulfur carrier protein TusA family
FY534_03700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY534_03705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY534_03705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY534_03715	COG0730	response to heat
FY534_03720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY534_03725	COG1937	Protein conserved in bacteria
FY534_03735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY534_03745	COG1414	Transcriptional regulator
FY534_03760	COG1012	belongs to the aldehyde dehydrogenase family
FY534_03775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY534_03780	COG3842	ATPase activity
FY534_03795	COG1234	tRNA 3'-trailer cleavage
FY534_03805	COG0300	oxidoreductase activity
FY534_03815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY534_03835	COG1216	Glycosyl transferase, family 2
FY534_03840	COG0667	Aldo Keto reductase
FY534_03845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY534_03850	COG1733	regulation of RNA biosynthetic process
FY534_03870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FY534_03880	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY534_03885	COG2070	2-Nitropropane dioxygenase
FY534_03890	COG0010	Belongs to the arginase family
FY534_03895	COG1228	amidohydrolase
FY534_03910	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY534_03915	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FY534_03920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY534_03925	COG0318	PFAM AMP-dependent synthetase and ligase
FY534_03930	COG3103	Sh3 type 3 domain protein
FY534_03930	COG1388	LysM domain
FY534_03930	COG0791	NLP P60 protein
FY534_03935	COG0697	spore germination
FY534_03940	COG2224	Isocitrate lyase
FY534_03960	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY534_04000	COG2827	Endonuclease containing a URI domain
FY534_04015	COG2814	Major facilitator Superfamily
FY534_04025	COG0154	amidase activity
FY534_04030	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY534_04035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY534_04055	COG3973	AAA domain
FY534_04065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY534_04070	COG1584	GPR1 FUN34 yaaH family protein
FY534_04105	COG0579	oxidoreductase
FY534_04110	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY534_04145	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY534_04170	COG1482	cell wall glycoprotein biosynthetic process
FY534_04180	COG3344	reverse transcriptase
FY534_04185	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY534_04190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY534_04195	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY534_04200	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY534_04205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY534_04230	COG1609	Transcriptional regulator
FY534_04240	COG0463	Glycosyl transferase, family 2
FY534_04255	COG1215	transferase activity, transferring glycosyl groups
FY534_04265	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FY534_04270	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY534_04285	COG3546	catalase activity
FY534_04290	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FY534_04315	COG0567	Dehydrogenase, E1 component
FY534_04320	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY534_04325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY534_04335	COG0584	glycerophosphoryl diester phosphodiesterase
FY534_04350	COG2508	Transcriptional regulator
FY534_04355	COG3842	ATPase activity
FY534_04360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY534_04365	COG0205	6-phosphofructokinase activity
FY534_04375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY534_04380	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY534_04385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY534_04390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY534_04390	COG0072	phenylalanine-tRNA ligase activity
FY534_04400	COG1286	toxin biosynthetic process
FY534_04410	COG1193	negative regulation of DNA recombination
FY534_04415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY534_04420	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY534_04430	COG0840	transmembrane signaling receptor activity
FY534_04445	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FY534_04445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY534_04455	COG0217	transcriptional regulatory protein
FY534_04465	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY534_04470	COG0632	four-way junction helicase activity
FY534_04475	COG2255	four-way junction helicase activity
FY534_04480	COG1191	sigma factor activity
FY534_04490	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY534_04495	COG0343	queuine tRNA-ribosyltransferase activity
FY534_04515	COG2323	membrane
FY534_04520	COG2244	polysaccharide biosynthetic process
FY534_04530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FY534_04535	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FY534_04540	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY534_04545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY534_04550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY534_04555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FY534_04575	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY534_04590	COG0569	domain protein
FY534_04590	COG0475	glutathione-regulated potassium exporter activity
FY534_04600	COG0456	acetyltransferase
FY534_04605	COG0714	Associated with various cellular activities
FY534_04630	COG0791	NLP P60 protein
FY534_04630	COG1388	LysM domain
FY534_04635	COG3344	reverse transcriptase
FY534_04640	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FY534_04645	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY534_04650	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY534_04660	COG1929	Belongs to the glycerate kinase type-1 family
FY534_04665	COG3253	May function as heme-dependent peroxidase
FY534_04670	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY534_04675	COG1321	iron dependent repressor
FY534_04690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY534_04695	COG0477	Major facilitator Superfamily
FY534_04705	COG1074	ATP-dependent DNA helicase activity
FY534_04710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY534_04720	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY534_04725	COG0303	'Molybdopterin
FY534_04730	COG0667	Aldo Keto reductase
FY534_04735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FY534_04740	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_04745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY534_04760	COG0183	Belongs to the thiolase family
FY534_04765	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FY534_04765	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY534_04775	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FY534_04785	COG2814	Major facilitator Superfamily
FY534_04795	COG1131	(ABC) transporter
FY534_04825	COG0124	histidyl-tRNA synthetase
FY534_04830	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY534_04850	COG1959	2 iron, 2 sulfur cluster binding
FY534_04855	COG1104	cysteine desulfurase activity
FY534_04870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY534_04875	COG0628	permease
FY534_04880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY534_04885	COG4472	Bacterial protein of unknown function (DUF965)
FY534_04890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY534_04895	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY534_04905	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FY534_04910	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FY534_04915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY534_04920	COG1534	Rna-binding protein
FY534_04925	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY534_04930	COG1713	HD superfamily hydrolase involved in NAD metabolism
FY534_04935	COG0799	negative regulation of ribosome biogenesis
FY534_04945	COG1596	polysaccharide export
FY534_04945	COG1555	photosystem II stabilization
FY534_04955	COG1252	NADH dehydrogenase
FY534_04960	COG1466	dna polymerase III delta subunit
FY534_04970	COG0268	Binds directly to 16S ribosomal RNA
FY534_04975	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FY534_04980	COG0741	lytic transglycosylase activity
FY534_04995	COG0481	GTPase activity
FY534_05000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY534_05005	COG1420	regulation of RNA biosynthetic process
FY534_05015	COG0443	Heat shock 70 kDa protein
FY534_05020	COG0484	heat shock protein binding
FY534_05025	COG2264	protein methyltransferase activity
FY534_05030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FY534_05035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY534_05045	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY534_05050	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY534_05055	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY534_05060	COG1610	YqeY-like protein
FY534_05075	COG1702	phosphate starvation-inducible protein PhoH
FY534_05080	COG1480	7TM receptor with intracellular HD hydrolase
FY534_05085	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY534_05090	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY534_05095	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY534_05105	COG1381	Involved in DNA repair and RecF pathway recombination
FY534_05110	COG0517	IMP dehydrogenase activity
FY534_05115	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY534_05120	COG0358	DNA primase activity
FY534_05125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY534_05130	COG1960	acyl-CoA dehydrogenase activity
FY534_05145	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FY534_05155	COG0454	-acetyltransferase
FY534_05160	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FY534_05175	COG3189	MarR family transcriptional regulator
FY534_05195	COG2346	COG2346, Truncated hemoglobins
FY534_05205	COG0791	NLP P60 protein
FY534_05205	COG3883	PFAM NLP P60 protein
FY534_05235	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FY534_05240	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY534_05245	COG0697	spore germination
FY534_05255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY534_05260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY534_05260	COG1648	precorrin-2 dehydrogenase activity
FY534_05265	COG0602	queuosine metabolic process
FY534_05270	COG0720	synthase
FY534_05275	COG3437	response regulator, receiver
FY534_05275	COG2770	Histidine kinase
FY534_05280	COG1733	regulation of RNA biosynthetic process
FY534_05285	COG2096	Adenosyltransferase
FY534_05290	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_05305	COG1575	Belongs to the MenA family. Type 1 subfamily
FY534_05325	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FY534_05335	COG0025	NhaP-type Na H and K H
FY534_05340	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY534_05355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY534_05365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY534_05370	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY534_05375	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FY534_05380	COG0704	Plays a role in the regulation of phosphate uptake
FY534_05425	COG1509	lysine 2,3-aminomutase activity
FY534_05435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY534_05445	COG2271	Major facilitator Superfamily
FY534_05470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY534_05530	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY534_05535	COG0740	serine-type endopeptidase activity
FY534_05540	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY534_05545	COG1067	ATP-dependent peptidase activity
FY534_05545	COG0470	DNA polymerase III
FY534_05555	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY534_05565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY534_05570	COG0181	hydroxymethylbilane synthase activity
FY534_05580	COG0113	porphobilinogen synthase activity
FY534_05585	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FY534_05600	COG0525	valine-tRNA ligase activity
FY534_05605	COG0285	dihydrofolate synthase activity
FY534_05610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY534_05630	COG1388	LysM domain
FY534_05630	COG3584	3D domain protein
FY534_05640	COG2003	Belongs to the UPF0758 family
FY534_05645	COG1077	Cell shape determining protein MreB Mrl
FY534_05660	COG0850	regulation of cytokinetic process
FY534_05665	COG2894	cell division
FY534_05690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY534_05720	COG2165	general secretion pathway protein
FY534_05740	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY534_05745	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY534_05755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FY534_05760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY534_05765	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY534_05770	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY534_05780	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY534_05785	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY534_05790	COG3854	ATPases associated with a variety of cellular activities
FY534_05830	COG0511	ligase activity, forming carbon-carbon bonds
FY534_05840	COG1302	Protein conserved in bacteria
FY534_05855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY534_05860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY534_05865	COG0492	ferredoxin-NADP+ reductase activity
FY534_05870	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY534_05875	COG1570	exodeoxyribonuclease VII activity
FY534_05880	COG1722	exodeoxyribonuclease VII activity
FY534_05895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY534_05900	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY534_05910	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY534_05915	COG0497	DNA recombination
FY534_05920	COG0750	zinc metalloprotease
FY534_05925	COG0745	RESPONSE REGULATOR receiver
FY534_05935	COG2318	DinB family
FY534_05945	COG1388	LysM domain
FY534_05945	COG3584	3D domain protein
FY534_05955	COG1388	LysM domain
FY534_05955	COG3942	CHAP domain
FY534_05965	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FY534_05970	COG0701	Predicted permease
FY534_05975	COG3858	chitin binding
FY534_05980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY534_05985	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FY534_06000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FY534_06005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY534_06010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY534_06015	COG0022	dehydrogenase e1 component
FY534_06020	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY534_06025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY534_06030	COG0321	lipoyl(octanoyl) transferase activity
FY534_06035	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY534_06035	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY534_06040	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY534_06045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY534_06055	COG2195	Cleaves the N-terminal amino acid of tripeptides
FY534_06065	COG1300	Membrane
FY534_06075	COG4974	Belongs to the 'phage' integrase family
FY534_06080	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY534_06090	COG1686	Belongs to the peptidase S11 family
FY534_06105	COG2172	sigma factor antagonist activity
FY534_06110	COG1191	sigma factor activity
FY534_06120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY534_06140	COG0805	protein transport
FY534_06145	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY534_06155	COG1595	DNA-templated transcription, initiation
FY534_06165	COG1994	Peptidase M50
FY534_06170	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY534_06175	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY534_06185	COG3874	Sporulation protein YtfJ
FY534_06190	COG2715	membrane protein required for spore maturation
FY534_06195	COG0700	Nucleoside recognition
FY534_06200	COG1187	pseudouridine synthase activity
FY534_06205	COG0745	RESPONSE REGULATOR receiver
FY534_06210	COG5002	protein histidine kinase activity
FY534_06220	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FY534_06240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY534_06245	COG2226	methyltransferase
FY534_06255	COG0210	DNA helicase
FY534_06280	COG1609	Transcriptional regulator
FY534_06285	COG4862	establishment of competence for transformation
FY534_06290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FY534_06310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY534_06335	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY534_06340	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY534_06345	COG0509	glycine decarboxylation via glycine cleavage system
FY534_06350	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FY534_06370	COG2226	methyltransferase
FY534_06380	COG0105	UTP biosynthetic process
FY534_06390	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY534_06400	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY534_06405	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY534_06435	COG2814	Major facilitator Superfamily
FY534_06440	COG0730	response to heat
FY534_06450	COG1012	belongs to the aldehyde dehydrogenase family
FY534_06460	COG2271	Major facilitator Superfamily
FY534_06480	COG1271	oxidase subunit
FY534_06485	COG2197	response regulator
FY534_06490	COG4585	Histidine kinase
FY534_06510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY534_06515	COG0492	ferredoxin-NADP+ reductase activity
FY534_06520	COG0667	Aldo Keto reductase
FY534_06530	COG0564	pseudouridine synthase activity
FY534_06535	COG1363	Peptidase, m42
FY534_06540	COG1363	Peptidase, m42
FY534_06545	COG1363	Peptidase, m42
FY534_06550	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY534_06555	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY534_06565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY534_06570	COG0134	indole-3-glycerol-phosphate synthase activity
FY534_06575	COG0135	phosphoribosylanthranilate isomerase activity
FY534_06580	COG0133	tryptophan synthase activity
FY534_06590	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FY534_06595	COG0287	Prephenate dehydrogenase
FY534_06600	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY534_06615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FY534_06620	COG3949	Membrane
FY534_06625	COG0473	3-isopropylmalate dehydrogenase activity
FY534_06630	COG1968	undecaprenyl-diphosphatase activity
FY534_06635	COG3314	Sporulation integral membrane protein YlbJ
FY534_06640	COG1694	Mazg nucleotide pyrophosphohydrolase
FY534_06650	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY534_06655	COG0438	transferase activity, transferring glycosyl groups
FY534_06660	COG0617	tRNA 3'-terminal CCA addition
FY534_06675	COG1199	ATP-dependent helicase activity
FY534_06675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY534_06680	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY534_06685	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FY534_06690	COG0402	S-adenosylhomocysteine deaminase activity
FY534_06695	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY534_06715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY534_06720	COG3344	reverse transcriptase
FY534_06725	COG0017	Asparaginyl-tRNA synthetase
FY534_06730	COG3935	DnaD domain protein
FY534_06735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY534_06740	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY534_06745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FY534_06750	COG1566	PFAM secretion protein HlyD family protein
FY534_06755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY534_06760	COG1271	oxidase subunit
FY534_06765	COG1294	oxidase, subunit
FY534_06770	COG0425	Belongs to the sulfur carrier protein TusA family
FY534_06770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY534_06775	COG1119	ATPase activity
FY534_06780	COG1506	peptidase
FY534_06785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY534_06790	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FY534_06795	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FY534_06800	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_06805	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY534_06805	COG0646	methionine synthase
FY534_06810	COG1410	methionine synthase
FY534_06810	COG0646	methionine synthase
FY534_06825	COG0423	glycine-tRNA ligase activity
FY534_06835	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY534_06840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY534_06845	COG1846	Transcriptional regulator
FY534_06850	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_06865	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY534_06870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY534_06880	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY534_06880	COG1902	pentaerythritol trinitrate reductase activity
FY534_06890	COG1960	acyl-CoA dehydrogenase activity
FY534_06895	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FY534_06900	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_06910	COG2197	response regulator
FY534_06915	COG0667	Aldo Keto reductase
FY534_06930	COG2814	Major facilitator Superfamily
FY534_06940	COG1054	Belongs to the UPF0176 family
FY534_06950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FY534_06955	COG1053	succinate dehydrogenase
FY534_06960	COG2009	succinate dehydrogenase
FY534_06965	COG0322	excinuclease ABC activity
FY534_06990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY534_07000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY534_07005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY534_07015	COG0387	Pfam Sodium calcium exchanger
FY534_07055	COG0463	Glycosyl transferase, family 2
FY534_07065	COG1846	Transcriptional regulator
FY534_07115	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY534_07120	COG0647	UMP catabolic process
FY534_07130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY534_07150	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY534_07170	COG3850	Histidine kinase
FY534_07170	COG5002	protein histidine kinase activity
FY534_07175	COG3850	Histidine kinase
FY534_07175	COG5002	protein histidine kinase activity
FY534_07180	COG0745	RESPONSE REGULATOR receiver
FY534_07230	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY534_07250	COG2203	Gaf domain
FY534_07250	COG3706	GGDEF domain
FY534_07250	COG4251	negative regulation of phosphorylation
FY534_07250	COG5001	Diguanylate cyclase
FY534_07295	COG0697	spore germination
FY534_07310	COG2226	methyltransferase
FY534_07315	COG2002	toxin-antitoxin pair type II binding
FY534_07320	COG2199	diguanylate cyclase activity
FY534_07320	COG2200	EAL domain
FY534_07325	COG2176	DNA-directed DNA polymerase activity
FY534_07460	COG1487	ribonuclease activity
FY534_07515	COG3547	Transposase (IS116 IS110 IS902 family)
FY534_07545	COG1131	(ABC) transporter
FY534_07585	COG0697	spore germination
FY534_07665	COG0789	Transcriptional regulator
FY534_07670	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_07685	COG1388	LysM domain
FY534_07705	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FY534_07760	COG0464	growth
FY534_07800	COG5002	protein histidine kinase activity
FY534_07805	COG2197	response regulator
FY534_07810	COG5001	Diguanylate cyclase
FY534_07810	COG3300	MHYT domain
FY534_07825	COG1215	transferase activity, transferring glycosyl groups
FY534_07885	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY534_07900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY534_07900	COG1199	ATP-dependent helicase activity
FY534_07915	COG0582	viral genome integration into host DNA
FY534_07920	COG2002	toxin-antitoxin pair type II binding
FY534_08055	COG0582	viral genome integration into host DNA
FY534_08070	COG3385	transposase activity
FY534_08085	COG0174	glutamine synthetase
FY534_08090	COG0789	Transcriptional regulator
FY534_08095	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FY534_08110	COG0464	growth
FY534_08170	COG1923	regulation of RNA biosynthetic process
FY534_08175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY534_08180	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY534_08190	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY534_08195	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY534_08205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY534_08210	COG0384	phenazine biosynthesis protein PhzF
FY534_08215	COG0189	ligase activity
FY534_08245	COG2359	stage V sporulation protein S
FY534_08250	COG1692	metallophosphoesterase
FY534_08255	COG1418	mRNA catabolic process
FY534_08265	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY534_08270	COG0513	Belongs to the DEAD box helicase family
FY534_08275	COG1546	Belongs to the CinA family
FY534_08275	COG1058	Belongs to the CinA family
FY534_08280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY534_08290	COG1426	Protein conserved in bacteria
FY534_08315	COG1674	ftsk spoiiie
FY534_08325	COG0740	serine-type endopeptidase activity
FY534_08330	COG1914	H( )-stimulated, divalent metal cation uptake system
FY534_08340	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FY534_08355	COG0527	aspartate kinase activity
FY534_08360	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY534_08365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY534_08370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY534_08380	COG0612	Peptidase, M16
FY534_08385	COG0726	polysaccharide deacetylase
FY534_08390	COG1185	polyribonucleotide nucleotidyltransferase activity
FY534_08395	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY534_08400	COG0196	riboflavin kinase activity
FY534_08405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY534_08415	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY534_08435	COG0195	Participates in both transcription termination and antitermination
FY534_08440	COG0779	Required for maturation of 30S ribosomal subunits
FY534_08445	COG1217	gtp-binding protein TYPA
FY534_08450	COG0077	Prephenate dehydratase
FY534_08450	COG1605	Chorismate mutase
FY534_08455	COG2176	DNA-directed DNA polymerase activity
FY534_08460	COG0750	zinc metalloprotease
FY534_08465	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY534_08470	COG4589	Belongs to the CDS family
FY534_08475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY534_08480	COG0233	cytoplasmic translational termination
FY534_08485	COG0528	UMP kinase activity
FY534_08490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY534_08495	COG0052	Belongs to the universal ribosomal protein uS2 family
FY534_08505	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY534_08520	COG0643	Histidine kinase
FY534_08520	COG2198	Histidine kinase
FY534_08525	COG0455	bacterial-type flagellum organization
FY534_08530	COG1419	protein localization to endoplasmic reticulum
FY534_08535	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY534_08540	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY534_08550	COG1987	bacterial-type flagellum assembly
FY534_08555	COG1338	Plays a role in the flagellum-specific transport system
FY534_08565	COG2201	protein-glutamate methylesterase activity
FY534_08570	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY534_08570	COG1776	CheC inhibitor of MCP methylation
FY534_08575	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY534_08590	COG4786	Flagellar basal body rod
FY534_08600	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY534_08620	COG1157	protein secretion by the type III secretion system
FY534_08630	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY534_08635	COG1766	The M ring may be actively involved in energy transduction
FY534_08640	COG1677	Flagellar hook-basal body complex protein FliE
FY534_08650	COG1815	bacterial-type flagellum-dependent cell motility
FY534_08655	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY534_08660	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY534_08665	COG4974	Belongs to the 'phage' integrase family
FY534_08670	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY534_08675	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY534_08680	COG0758	DNA mediated transformation
FY534_08685	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY534_08690	COG0045	succinate-CoA ligase (ADP-forming) activity
FY534_08705	COG0792	nuclease activity
FY534_08720	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY534_08725	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FY534_08730	COG0335	large ribosomal subunit rRNA binding
FY534_08755	COG1607	acyl-coa hydrolase
FY534_08760	COG0739	heme binding
FY534_08765	COG0824	Thioesterase
FY534_08770	COG0564	pseudouridine synthase activity
FY534_08775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY534_08795	COG0336	Belongs to the RNA methyltransferase TrmD family
FY534_08800	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY534_08810	COG1837	Belongs to the UPF0109 family
FY534_08815	COG0228	four-way junction DNA binding
FY534_08820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY534_08830	COG0552	protein localization to endoplasmic reticulum
FY534_08835	COG1196	nuclear chromosome segregation
FY534_08840	COG0571	ribonuclease III activity
FY534_08845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY534_08850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY534_08855	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_08860	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY534_08865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY534_08870	COG0416	fatty acid biosynthetic process
FY534_08875	COG1349	DNA-binding transcription factor activity
FY534_08880	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY534_08890	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY534_08895	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY534_08900	COG0742	ribosomal rna small subunit methyltransferase
FY534_08910	COG0154	amidase activity
FY534_08915	COG0438	transferase activity, transferring glycosyl groups
FY534_08925	COG0688	phosphatidylethanolamine metabolic process
FY534_08935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY534_08940	COG1461	Dihydroxyacetone kinase
FY534_08945	COG1302	Protein conserved in bacteria
FY534_08950	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY534_08960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FY534_08965	COG1162	GTPase activity
FY534_08970	COG0515	serine threonine protein kinase
FY534_08970	COG2815	serine threonine protein kinase
FY534_08975	COG0631	protein serine/threonine phosphatase activity
FY534_08980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY534_08985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY534_08985	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY534_08990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY534_08995	COG0242	peptide deformylase activity
FY534_09000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FY534_09005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY534_09010	COG1758	RNA polymerase activity
FY534_09015	COG0194	GDP metabolic process
FY534_09025	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FY534_09040	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FY534_09065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY534_09070	COG0540	Belongs to the ATCase OTCase family
FY534_09080	COG3344	reverse transcriptase
FY534_09095	COG0564	pseudouridine synthase activity
FY534_09100	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY534_09105	COG1809	phosphosulfolactate synthase activity
FY534_09115	COG3599	regulation of cell shape
FY534_09130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY534_09135	COG1496	oxidoreductase activity
FY534_09140	COG1873	PFAM PRC-barrel domain
FY534_09145	COG1191	sigma factor activity
FY534_09150	COG1191	sigma factor activity
FY534_09160	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY534_09165	COG0849	cell division
FY534_09170	COG3856	small basic protein
FY534_09185	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY534_09190	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY534_09195	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY534_09200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY534_09205	COG0772	Belongs to the SEDS family
FY534_09210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY534_09215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY534_09220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY534_09225	COG0768	penicillin binding
FY534_09235	COG0275	rRNA processing
FY534_09240	COG2001	Belongs to the MraZ family
FY534_09245	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FY534_09250	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY534_09255	COG1024	Enoyl-CoA hydratase
FY534_09260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY534_09265	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY534_09270	COG0439	Biotin carboxylase
FY534_09275	COG0300	oxidoreductase activity
FY534_09300	COG0301	tRNA thio-modification
FY534_09305	COG1104	cysteine desulfurase activity
FY534_09310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FY534_09320	COG0740	serine-type endopeptidase activity
FY534_09350	COG3679	Belongs to the UPF0342 family
FY534_09355	COG3906	Belongs to the UPF0473 family
FY534_09360	COG2271	Major facilitator Superfamily
FY534_09365	COG0753	catalase activity
FY534_09370	COG4948	Mandelate Racemase Muconate Lactonizing
FY534_09385	COG1216	Glycosyl transferase, family 2
FY534_09400	COG0438	transferase activity, transferring glycosyl groups
FY534_09410	COG4191	Histidine kinase
FY534_09415	COG2017	converts alpha-aldose to the beta-anomer
FY534_09420	COG2814	Major facilitator Superfamily
FY534_09425	COG1070	Carbohydrate kinase
FY534_09430	COG2115	Belongs to the xylose isomerase family
FY534_09435	COG1940	carbohydrate kinase activity
FY534_09445	COG2814	Major facilitator Superfamily
FY534_09450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY534_09465	COG1802	Transcriptional regulator
FY534_09470	COG1132	(ABC) transporter
FY534_09475	COG1609	Transcriptional regulator
FY534_09480	COG1070	Carbohydrate kinase
FY534_09485	COG2271	Major facilitator Superfamily
FY534_09505	COG2814	Major facilitator Superfamily
FY534_09515	COG4372	Transposase
FY534_09545	COG4974	Belongs to the 'phage' integrase family
FY534_09580	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FY534_09585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY534_09590	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY534_09600	COG3383	formate dehydrogenase (NAD+) activity
FY534_09610	COG0165	Argininosuccinate lyase
FY534_09615	COG0137	argininosuccinate synthase activity
FY534_09620	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY534_09625	COG0067	glutamate synthase
FY534_09625	COG0070	glutamate synthase
FY534_09625	COG0069	glutamate synthase activity
FY534_09630	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FY534_09635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY534_09645	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY534_09660	COG1842	Phage shock protein A
FY534_09685	COG0512	Glutamine amidotransferase of anthranilate synthase
FY534_09740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FY534_09745	COG0352	thiamine-phosphate diphosphorylase activity
FY534_09750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY534_09755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY534_09755	COG2022	thiamine diphosphate biosynthetic process
FY534_09765	COG2022	thiamine diphosphate biosynthetic process
FY534_09785	COG1984	allophanate hydrolase subunit 2
FY534_09790	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY534_09805	COG1414	Transcriptional regulator
FY534_09820	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY534_09825	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY534_09840	COG2176	DNA-directed DNA polymerase activity
FY534_09865	COG2860	membrane
FY534_09875	COG0531	amino acid
FY534_09880	COG2186	Transcriptional regulator
FY534_09890	COG1139	Iron-sulfur cluster binding protein
FY534_09895	COG1556	Lactate utilization protein
FY534_09900	COG1349	DNA-binding transcription factor activity
FY534_09905	COG4952	isomerase
FY534_09915	COG1070	Carbohydrate kinase
FY534_09920	COG1070	Carbohydrate kinase
FY534_09925	COG3254	rhamnose metabolic process
FY534_09940	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FY534_09945	COG1562	ergosterol biosynthetic process
FY534_09950	COG1562	ergosterol biosynthetic process
FY534_09955	COG1657	PFAM Prenyltransferase squalene oxidase
FY534_09960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY534_09975	COG1304	FMN binding
FY534_09985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY534_10000	COG2199	diguanylate cyclase activity
FY534_10000	COG3287	FIST C domain
FY534_10000	COG2200	EAL domain
FY534_10015	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FY534_10015	COG0674	pyruvate-flavodoxin oxidoreductase activity
FY534_10020	COG1013	pyruvate-flavodoxin oxidoreductase activity
FY534_10035	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FY534_10040	COG1363	Peptidase, m42
FY534_10045	COG3377	Domain of unknown function (DUF1805)
FY534_10055	COG0586	Pfam SNARE associated Golgi protein
FY534_10060	COG1078	dGTPase activity
FY534_10065	COG0316	Belongs to the HesB IscA family
FY534_10070	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY534_10075	COG1982	Orn Lys Arg decarboxylase major
FY534_10095	COG0436	Aminotransferase
FY534_10100	COG0772	Belongs to the SEDS family
FY534_10115	COG0772	Belongs to the SEDS family
FY534_10125	COG1956	GAF domain-containing protein
FY534_10140	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_10150	COG2050	protein possibly involved in aromatic compounds catabolism
FY534_10160	COG0318	PFAM AMP-dependent synthetase and ligase
FY534_10165	COG1285	pathogenesis
FY534_10170	COG0083	homoserine kinase activity
FY534_10175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FY534_10180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY534_10185	COG2814	Major facilitator Superfamily
FY534_10190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FY534_10195	COG0612	Peptidase, M16
FY534_10200	COG0612	Peptidase, M16
FY534_10210	COG0477	Major facilitator Superfamily
FY534_10215	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY534_10215	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY534_10215	COG1703	isobutyryl-CoA mutase activity
FY534_10220	COG1309	transcriptional regulator
FY534_10225	COG0768	penicillin binding
FY534_10240	COG5609	conserved protein (DUF2294)
FY534_10245	COG3002	Belongs to the UPF0753 family
FY534_10250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY534_10255	COG1960	acyl-CoA dehydrogenase activity
FY534_10260	COG0183	Belongs to the thiolase family
FY534_10265	COG1024	Enoyl-CoA hydratase
FY534_10265	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY534_10270	COG0537	adenosine 5'-monophosphoramidase activity
FY534_10285	COG0671	phosphoesterase, PA-phosphatase related
FY534_10300	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FY534_10325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY534_10330	COG1024	Enoyl-CoA hydratase
FY534_10335	COG0531	amino acid
FY534_10345	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY534_10350	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY534_10355	COG0483	inositol monophosphate 1-phosphatase activity
FY534_10360	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY534_10360	COG2124	cytochrome p450
FY534_10370	COG0114	fumarate hydratase activity
FY534_10385	COG4946	Tricorn protease homolog
FY534_10385	COG1506	peptidase
FY534_10385	COG0823	Involved in the tonB-independent uptake of proteins
FY534_10395	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FY534_10400	COG2086	electron transfer activity
FY534_10405	COG1309	transcriptional regulator
FY534_10415	COG1959	2 iron, 2 sulfur cluster binding
FY534_10425	COG0719	Fe-S assembly protein
FY534_10430	COG0822	iron-sulfur transferase activity
FY534_10435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY534_10440	COG0719	Fe-S assembly protein
FY534_10445	COG0396	ATPase activity
FY534_10455	COG0686	Belongs to the AlaDH PNT family
FY534_10470	COG1595	DNA-templated transcription, initiation
FY534_10475	COG0167	dihydroorotate dehydrogenase activity
FY534_10490	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FY534_10495	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY534_10500	COG0302	gtp cyclohydrolase
FY534_10530	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_10535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY534_10540	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FY534_10545	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY534_10550	COG1363	Peptidase, m42
FY534_10570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY534_10570	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY534_10575	COG1215	transferase activity, transferring glycosyl groups
FY534_10585	COG0564	pseudouridine synthase activity
FY534_10590	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY534_10595	COG2155	Conserved Protein
FY534_10605	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY534_10605	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FY534_10630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY534_10635	COG1376	ErfK ybiS ycfS ynhG family protein
FY534_10640	COG1960	acyl-CoA dehydrogenase activity
FY534_10645	COG2223	nitrite transmembrane transporter activity
FY534_10650	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FY534_10680	COG0482	sulfurtransferase activity
FY534_10685	COG0768	penicillin binding
FY534_10690	COG0583	DNA-binding transcription factor activity
FY534_10715	COG1122	ATPase activity
FY534_10720	COG4721	ABC-type cobalt transport system, permease component
FY534_10730	COG0697	spore germination
FY534_10735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY534_10735	COG0140	phosphoribosyl-ATP diphosphatase activity
FY534_10740	COG0107	imidazoleglycerol-phosphate synthase activity
FY534_10745	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY534_10755	COG0131	Imidazoleglycerol-phosphate dehydratase
FY534_10765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY534_10770	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY534_10780	COG0437	4 iron, 4 sulfur cluster binding
FY534_10790	COG0583	DNA-binding transcription factor activity
FY534_10795	COG0583	DNA-binding transcription factor activity
FY534_10815	COG1595	DNA-templated transcription, initiation
FY534_10820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY534_10825	COG1012	belongs to the aldehyde dehydrogenase family
FY534_10835	COG1024	Enoyl-CoA hydratase
FY534_10850	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FY534_10855	COG2151	metal-sulfur cluster biosynthetic enzyme
FY534_10870	COG3396	Phenylacetate-CoA oxygenase
FY534_10875	COG1309	transcriptional regulator
FY534_10895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY534_10900	COG4166	transmembrane transport
FY534_10910	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY534_10915	COG0531	amino acid
FY534_10920	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY534_10925	COG1830	Aldolase
FY534_10935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY534_10940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY534_10945	COG0116	Belongs to the methyltransferase superfamily
FY534_10950	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY534_10965	COG1979	alcohol dehydrogenase
FY534_10975	COG2081	HI0933 family
FY534_10990	COG0424	maF-like protein
FY534_10995	COG0626	cystathionine gamma-synthase activity
FY534_11010	COG2363	Small membrane protein
FY534_11015	COG1215	transferase activity, transferring glycosyl groups
FY534_11045	COG2309	aminopeptidase activity
FY534_11050	COG3300	MHYT domain
FY534_11050	COG5001	Diguanylate cyclase
FY534_11075	COG0791	NLP P60 protein
FY534_11075	COG1388	LysM domain
FY534_11080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY534_11100	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY534_11135	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FY534_11140	COG0705	Rhomboid family
FY534_11155	COG0577	efflux transmembrane transporter activity
FY534_11180	COG0517	IMP dehydrogenase activity
FY534_11185	COG3239	Fatty acid desaturase
FY534_11195	COG0372	Belongs to the citrate synthase family
FY534_11205	COG1971	Probably functions as a manganese efflux pump
FY534_11215	COG0066	3-isopropylmalate dehydratase activity
FY534_11220	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY534_11230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY534_11235	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY534_11265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY534_11275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY534_11280	COG0366	Alpha amylase catalytic
FY534_11295	COG1653	transport
FY534_11300	COG1609	Transcriptional regulator
FY534_11305	COG0531	amino acid
FY534_11310	COG0586	Pfam SNARE associated Golgi protein
FY534_11330	COG1388	LysM domain
FY534_11330	COG3858	chitin binding
FY534_11335	COG5002	protein histidine kinase activity
FY534_11355	COG4191	Histidine kinase
FY534_11385	COG0697	spore germination
FY534_11390	COG1388	LysM domain
FY534_11390	COG3858	chitin binding
FY534_11405	COG1132	(ABC) transporter
FY534_11410	COG1132	(ABC) transporter
FY534_11415	COG1827	regulation of RNA biosynthetic process
FY534_11420	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FY534_11425	COG1757	Na H antiporter
FY534_11430	COG2155	Conserved Protein
FY534_11440	COG2233	PERMEase
FY534_11450	COG0601	transmembrane transport
FY534_11455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY534_11465	COG4608	Belongs to the ABC transporter superfamily
FY534_11470	COG0444	Belongs to the ABC transporter superfamily
FY534_11475	COG2814	Major facilitator Superfamily
FY534_11485	COG5002	protein histidine kinase activity
FY534_11490	COG0095	Lipoate-protein ligase
FY534_11495	COG5002	protein histidine kinase activity
FY534_11500	COG0745	RESPONSE REGULATOR receiver
FY534_11505	COG0583	DNA-binding transcription factor activity
FY534_11515	COG1028	Short-chain dehydrogenase reductase Sdr
FY534_11550	COG0248	Ppx GppA phosphatase
FY534_11555	COG1072	(Pantothenic acid kinase))
FY534_11565	COG1612	heme a metabolic process
FY534_11570	COG0109	protoheme IX farnesyltransferase activity
FY534_11575	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY534_11580	COG1845	cytochrome c oxidase, subunit III
FY534_11585	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY534_11600	COG1012	belongs to the aldehyde dehydrogenase family
FY534_11605	COG5001	Diguanylate cyclase
FY534_11605	COG5002	protein histidine kinase activity
FY534_11610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY534_11615	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FY534_11620	COG1085	galactose-1-phosphate uridylyltransferase
FY534_11625	COG0475	glutathione-regulated potassium exporter activity
FY534_11625	COG0569	domain protein
FY534_11630	COG0475	glutathione-regulated potassium exporter activity
FY534_11630	COG0569	domain protein
FY534_11635	COG2205	protein histidine kinase activity
FY534_11640	COG0745	RESPONSE REGULATOR receiver
FY534_11645	COG4990	cell redox homeostasis
FY534_11650	COG0367	asparagine synthase
FY534_11660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY534_11670	COG0573	inorganic phosphate transmembrane transporter activity
FY534_11730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY534_11735	COG4989	oxidoreductase activity
FY534_11740	COG0667	Aldo Keto reductase
FY534_11760	COG1175	transmembrane transport
FY534_11770	COG0395	ABC-type sugar transport system, permease component
FY534_11775	COG1609	Transcriptional regulator
FY534_11780	COG1230	cation diffusion facilitator family transporter
FY534_11785	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FY534_11810	COG0237	dephospho-CoA kinase activity
FY534_11815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY534_11825	COG0039	L-malate dehydrogenase activity
FY534_11830	COG0538	isocitrate dehydrogenase activity
FY534_11840	COG2084	Dehydrogenase
FY534_11850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY534_11860	COG0825	malonyl-CoA metabolic process
FY534_11865	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY534_11875	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FY534_11880	COG0587	DNA-directed DNA polymerase activity
FY534_11885	COG4109	DRTGG domain
FY534_11890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FY534_11895	COG4993	Dehydrogenase
FY534_11905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY534_11910	COG0735	belongs to the Fur family
FY534_11915	COG0450	alkyl hydroperoxide reductase
FY534_11920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY534_11930	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FY534_11935	COG1473	amidohydrolase
FY534_11940	COG1438	arginine binding
FY534_11970	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY534_11980	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FY534_11995	COG2309	aminopeptidase activity
FY534_12000	COG2814	Major facilitator Superfamily
FY534_12005	COG0768	penicillin binding
FY534_12010	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY534_12015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY534_12015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY534_12025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY534_12025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY534_12045	COG1045	serine acetyltransferase
FY534_12055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY534_12060	COG3459	Glycosyltransferase 36 associated
FY534_12065	COG3459	Glycosyltransferase 36 associated
FY534_12070	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FY534_12075	COG2226	methyltransferase
FY534_12080	COG4496	protein, YerC YecD
FY534_12115	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY534_12125	COG0247	lactate metabolic process
FY534_12130	COG0277	FAD linked oxidase domain protein
FY534_12135	COG1414	Transcriptional regulator
FY534_12140	COG1620	l-lactate permease
FY534_12160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY534_12180	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY534_12185	COG2130	NADP-dependent
FY534_12190	COG0477	Major facilitator Superfamily
FY534_12195	COG0477	Major facilitator Superfamily
FY534_12200	COG0463	Glycosyl transferase, family 2
FY534_12215	COG0840	transmembrane signaling receptor activity
FY534_12215	COG5278	phosphoserine phosphatase activity
FY534_12220	COG0450	alkyl hydroperoxide reductase
FY534_12230	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY534_12235	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY534_12240	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY534_12245	COG2337	Toxic component of a toxin-antitoxin (TA) module
FY534_12250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY534_12265	COG2197	response regulator
FY534_12270	COG4585	Histidine kinase
FY534_12290	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY534_12295	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY534_12295	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY534_12300	COG0736	holo-[acyl-carrier-protein] synthase activity
FY534_12320	COG1012	belongs to the aldehyde dehydrogenase family
FY534_12325	COG1454	alcohol dehydrogenase
FY534_12360	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY534_12365	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY534_12380	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY534_12390	COG0069	glutamate synthase activity
FY534_12425	COG0662	Cupin 2, conserved barrel domain protein
FY534_12425	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FY534_12455	COG2814	Major facilitator Superfamily
FY534_12460	COG0789	Transcriptional regulator
FY534_12465	COG4499	WXG100 protein secretion system (Wss), protein YukC
FY534_12465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY534_12475	COG4846	Membrane protein involved in cytochrome C biogenesis
FY534_12480	COG2409	Drug exporters of the RND superfamily
FY534_12480	COG1033	growth of symbiont in host cell
FY534_12485	COG2409	Drug exporters of the RND superfamily
FY534_12485	COG1033	growth of symbiont in host cell
FY534_12500	COG3773	Cell wall hydrolase
FY534_12500	COG3409	Peptidoglycan-binding domain 1 protein
FY534_12515	COG1321	iron dependent repressor
FY534_12530	COG0395	ABC-type sugar transport system, permease component
FY534_12535	COG1175	transmembrane transport
FY534_12550	COG5002	protein histidine kinase activity
FY534_12565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY534_12580	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY534_12590	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY534_12595	COG1216	Glycosyl transferase, family 2
FY534_12605	COG0562	UDP-galactopyranose mutase
FY534_12620	COG1215	transferase activity, transferring glycosyl groups
FY534_12630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY534_12640	COG2199	diguanylate cyclase activity
FY534_12640	COG2203	Gaf domain
FY534_12660	COG5001	Diguanylate cyclase
FY534_12675	COG0484	heat shock protein binding
FY534_12685	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY534_12690	COG0768	penicillin binding
FY534_12695	COG0768	penicillin binding
FY534_12715	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY534_12720	COG0768	penicillin binding
FY534_12740	COG0656	L-ascorbic acid biosynthetic process
FY534_12750	COG0386	Belongs to the glutathione peroxidase family
FY534_12755	COG1376	ErfK ybiS ycfS ynhG family protein
FY534_12770	COG0531	amino acid
FY534_12780	COG0506	proline dehydrogenase activity
FY534_12785	COG0577	efflux transmembrane transporter activity
FY534_12785	COG1136	(ABC) transporter
FY534_12790	COG1136	(ABC) transporter
FY534_12805	COG1739	Uncharacterized protein family UPF0029
FY534_12845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY534_12850	COG4786	Flagellar basal body rod
FY534_12855	COG4786	Flagellar basal body rod
FY534_12860	COG1077	Cell shape determining protein MreB Mrl
FY534_12865	COG1609	Transcriptional regulator
FY534_12870	COG0739	heme binding
FY534_12885	COG3852	Histidine kinase
FY534_12890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY534_12905	COG1007	ATP synthesis coupled electron transport
FY534_12910	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY534_12915	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY534_12920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY534_12925	COG0713	ATP synthesis coupled electron transport
FY534_12935	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY534_12940	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY534_12945	COG0649	NAD binding
FY534_12950	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY534_12955	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY534_12960	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY534_12965	COG2226	methyltransferase
FY534_12970	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY534_12975	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY534_12980	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY534_12985	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY534_12990	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY534_12995	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY534_13000	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY534_13005	COG0356	it plays a direct role in the translocation of protons across the membrane
FY534_13025	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FY534_13030	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY534_13035	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY534_13040	COG2814	Major facilitator Superfamily
FY534_13045	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY534_13050	COG4475	Protein of unknown function (DUF436)
FY534_13055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY534_13060	COG1971	Probably functions as a manganese efflux pump
FY534_13065	COG0009	L-threonylcarbamoyladenylate synthase
FY534_13075	COG2890	protein-(glutamine-N5) methyltransferase activity
FY534_13080	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY534_13085	COG0254	rRNA binding
FY534_13100	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY534_13105	COG1494	fructose-1,6-bisphosphatase
FY534_13110	COG0477	Major facilitator Superfamily
FY534_13115	COG0436	Aminotransferase
FY534_13120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY534_13125	COG3246	L-lysine catabolic process to acetate
FY534_13130	COG1607	acyl-coa hydrolase
FY534_13135	COG2204	response regulator
FY534_13145	COG3343	RNA polymerase activity
FY534_13155	COG1960	acyl-CoA dehydrogenase activity
FY534_13160	COG1960	acyl-CoA dehydrogenase activity
FY534_13165	COG1024	Enoyl-CoA hydratase
FY534_13170	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY534_13175	COG0183	Belongs to the thiolase family
FY534_13180	COG2181	nitrate reductase activity
FY534_13180	COG0247	lactate metabolic process
FY534_13240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY534_13245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY534_13260	COG0038	chloride channel
FY534_13265	COG0582	viral genome integration into host DNA
FY534_13280	COG5012	cobalamin binding
FY534_13285	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY534_13290	COG1193	negative regulation of DNA recombination
FY534_13300	COG1509	lysine 2,3-aminomutase activity
FY534_13305	COG0604	alcohol dehydrogenase
FY534_13315	COG3829	transcription factor binding
FY534_13325	COG0010	Belongs to the arginase family
FY534_13330	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FY534_13335	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY534_13335	COG2755	lipolytic protein G-D-S-L family
FY534_13345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY534_13365	COG5416	Lipopolysaccharide assembly protein A domain
FY534_13380	COG1803	Methylglyoxal synthase
FY534_13385	COG0006	proline dipeptidase activity
FY534_13420	COG2030	dehydratase
FY534_13425	COG0788	formyltetrahydrofolate deformylase activity
FY534_13435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY534_13460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY534_13465	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY534_13480	COG5002	protein histidine kinase activity
FY534_13485	COG0745	RESPONSE REGULATOR receiver
FY534_13495	COG0305	Participates in initiation and elongation during chromosome replication
FY534_13500	COG0359	binds to the 23S rRNA
FY534_13510	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY534_13515	COG0629	single-stranded DNA binding
FY534_13520	COG0360	Binds together with S18 to 16S ribosomal RNA
FY534_13525	COG0012	GTP binding
FY534_13530	COG0243	molybdopterin cofactor binding
FY534_13535	COG4481	Protein conserved in bacteria
FY534_13540	COG0668	transmembrane transport
FY534_13560	COG1811	Na channel or pump
FY534_13565	COG1475	DNA binding
FY534_13570	COG1192	Involved in chromosome partitioning
FY534_13580	COG0357	Ribosomal RNA small subunit methyltransferase G
FY534_13585	COG0445	tRNA wobble uridine modification
FY534_13590	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY534_13595	COG1847	R3H domain protein
FY534_13600	COG0706	membrane insertase activity
FY534_13605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY534_13610	COG0594	ribonuclease P activity
FY534_13615	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY534_13700	COG0592	DNA-directed DNA polymerase activity
FY534_13710	COG3646	Phage regulatory protein
FY534_13845	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FY534_13865	COG1247	-acetyltransferase
FY534_13880	COG1192	Involved in chromosome partitioning
FY534_13955	COG2314	TM2 domain
FY534_13960	COG3437	response regulator, receiver
FY534_13960	COG0784	Response regulator, receiver
FY534_13965	COG0741	lytic transglycosylase activity
FY534_14055	COG4974	Belongs to the 'phage' integrase family
FY534_14120	COG2135	peptidase activity
FY534_14155	COG1061	Type III restriction enzyme res subunit
FY534_14275	COG3344	reverse transcriptase
FY534_14330	COG2176	DNA-directed DNA polymerase activity