locus-tag	class	description
VSAL_I0001	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VSAL_I0002	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VSAL_I0003	COG0706	membrane insertase activity
VSAL_I0004	COG0594	ribonuclease P activity
VSAL_I0005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VSAL_I0006	COG1126	abc transporter atp-binding protein
VSAL_I0009	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VSAL_I0010	COG0592	DNA-directed DNA polymerase activity
VSAL_I0011	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VSAL_I0012	COG0187	DNA topoisomerase II activity
VSAL_I0017	COG0459	protein refolding
VSAL_I0018	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VSAL_I0042	COG0606	chelatase, subunit chli
VSAL_I0043	COG0204	Acyl-transferase
VSAL_I0044	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VSAL_I0045	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VSAL_I0047	COG3084	Protein conserved in bacteria
VSAL_I0049	COG1272	protein, Hemolysin III
VSAL_I0051	COG1278	Cold shock
VSAL_I0053	COG0129	dihydroxy-acid dehydratase activity
VSAL_I0054	COG3978	acetolactate synthase activity
VSAL_I0058	COG1192	Involved in chromosome partitioning
VSAL_I0072	COG0569	domain protein
VSAL_I0073	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VSAL_I0073	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VSAL_I0075	COG0242	peptide deformylase activity
VSAL_I0076	COG1652	LysM domain
VSAL_I0077	COG0758	DNA mediated transformation
VSAL_I0078	COG2922	Belongs to the Smg family
VSAL_I0079	COG0551	DNA topoisomerase type I activity
VSAL_I0080	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VSAL_I0081	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VSAL_I0082	COG0009	L-threonylcarbamoyladenylate synthase
VSAL_I0083	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VSAL_I0085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VSAL_I0086	COG0583	DNA-binding transcription factor activity
VSAL_I0087	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VSAL_I0088	COG2960	long-chain fatty acid transporting porin activity
VSAL_I0089	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VSAL_I0090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VSAL_I0091	COG1309	transcriptional regulator
VSAL_I0092	COG0210	DNA helicase
VSAL_I0095	COG0747	negative chemotaxis
VSAL_I0097	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VSAL_I0098	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VSAL_I0100	COG0517	IMP dehydrogenase activity
VSAL_I0103	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSAL_I0103	COG3711	transcriptional antiterminator
VSAL_I0106	COG3964	amidohydrolase
VSAL_I0115	COG4372	Transposase
VSAL_I0118	COG2815	serine threonine protein kinase
VSAL_I0118	COG0515	serine threonine protein kinase
VSAL_I0120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VSAL_I0121	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VSAL_I0124	COG1965	Belongs to the frataxin family
VSAL_I0125	COG0019	diaminopimelate decarboxylase activity
VSAL_I0126	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VSAL_I0128	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VSAL_I0134	COG0076	glutamate decarboxylase activity
VSAL_I0135	COG3486	L-lysine 6-monooxygenase (NADPH) activity
VSAL_I0138	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VSAL_I0139	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VSAL_I0140	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VSAL_I0144	COG4372	Transposase
VSAL_I0146	COG0513	Belongs to the DEAD box helicase family
VSAL_I0147	COG3118	belongs to the thioredoxin family
VSAL_I0148	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
VSAL_I0150	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VSAL_I0157	COG1368	sulfuric ester hydrolase activity
VSAL_I0158	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VSAL_I0162	COG1519	Transferase
VSAL_I0169	COG2089	acid synthase
VSAL_I0170	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VSAL_I0171	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VSAL_I0174	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VSAL_I0180	COG1088	dTDP-glucose 4,6-dehydratase activity
VSAL_I0181	COG3083	sulfuric ester hydrolase activity
VSAL_I0182	COG3642	lipopolysaccharide core region biosynthetic process
VSAL_I0183	COG0859	PFAM glycosyl transferase family 9
VSAL_I0184	COG0463	Glycosyl transferase, family 2
VSAL_I0185	COG0438	transferase activity, transferring glycosyl groups
VSAL_I0186	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VSAL_I0187	COG1368	sulfuric ester hydrolase activity
VSAL_I0188	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VSAL_I0190	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VSAL_I0191	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VSAL_I0192	COG2003	Belongs to the UPF0758 family
VSAL_I0193	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VSAL_I0194	COG1309	transcriptional regulator
VSAL_I0195	COG1560	Kdo2-lipid A biosynthetic process
VSAL_I0196	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VSAL_I0197	COG2183	response to ionizing radiation
VSAL_I0199	COG2267	carboxylic ester hydrolase activity
VSAL_I0203	COG2205	protein histidine kinase activity
VSAL_I0204	COG0745	RESPONSE REGULATOR receiver
VSAL_I0207	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VSAL_I0208	COG1561	YicC-like family, N-terminal region
VSAL_I0210	COG0194	GDP metabolic process
VSAL_I0211	COG1758	RNA polymerase activity
VSAL_I0212	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VSAL_I0214	COG4372	Transposase
VSAL_I0217	COG3071	HemY protein
VSAL_I0218	COG2959	enzyme of heme biosynthesis
VSAL_I0219	COG1587	Uroporphyrinogen-III synthase
VSAL_I0220	COG0181	hydroxymethylbilane synthase activity
VSAL_I0222	COG0210	DNA helicase
VSAL_I0223	COG2962	Rard protein
VSAL_I0224	COG0514	ATP-dependent DNA helicase (RecQ)
VSAL_I0226	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VSAL_I0227	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VSAL_I0227	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VSAL_I0228	COG0218	Necessary for normal cell division and for the maintenance of normal septation
VSAL_I0231	COG3078	GTPase activator activity
VSAL_I0233	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VSAL_I0236	COG4372	Transposase
VSAL_I0238	COG0438	transferase activity, transferring glycosyl groups
VSAL_I0239	COG0463	Glycosyl transferase, family 2
VSAL_I0240	COG0859	PFAM glycosyl transferase family 9
VSAL_I0241	COG3642	lipopolysaccharide core region biosynthetic process
VSAL_I0242	COG3083	sulfuric ester hydrolase activity
VSAL_I0243	COG1088	dTDP-glucose 4,6-dehydratase activity
VSAL_I0249	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VSAL_I0252	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VSAL_I0253	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VSAL_I0254	COG2089	acid synthase
VSAL_I0261	COG1519	Transferase
VSAL_I0265	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VSAL_I0272	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VSAL_I0278	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
VSAL_I0278	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
VSAL_I0282	COG2852	Protein conserved in bacteria
VSAL_I0283	COG0149	triose-phosphate isomerase activity
VSAL_I0287	COG1494	fructose-1,6-bisphosphatase
VSAL_I0288	COG3074	FtsZ-dependent cytokinesis
VSAL_I0291	COG4372	Transposase
VSAL_I0292	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VSAL_I0293	COG1575	Belongs to the MenA family. Type 1 subfamily
VSAL_I0294	COG3954	Phosphoribulokinase
VSAL_I0295	COG3089	Belongs to the UPF0270 family
VSAL_I0296	COG0429	hydrolase of the alpha beta-hydrolase fold
VSAL_I0298	COG0488	(ABC) transporter
VSAL_I0299	COG2249	NAD(P)H dehydrogenase (quinone) activity
VSAL_I0301	COG1047	Peptidyl-prolyl cis-trans
VSAL_I0302	COG1047	Peptidyl-prolyl cis-trans
VSAL_I0303	COG2900	Belongs to the SlyX family
VSAL_I0305	COG0545	Peptidyl-prolyl cis-trans isomerase
VSAL_I0306	COG2964	Protein conserved in bacteria
VSAL_I0307	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VSAL_I0308	COG2923	Belongs to the DsrF TusC family
VSAL_I0310	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
VSAL_I0311	COG0049	tRNA binding
VSAL_I0312	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VSAL_I0319	COG0051	transcription antitermination factor activity, RNA binding
VSAL_I0320	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VSAL_I0321	COG0088	Forms part of the polypeptide exit tunnel
VSAL_I0322	COG0089	rRNA binding
VSAL_I0323	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VSAL_I0324	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VSAL_I0325	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VSAL_I0326	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VSAL_I0327	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VSAL_I0328	COG0255	Belongs to the universal ribosomal protein uL29 family
VSAL_I0329	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VSAL_I0330	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VSAL_I0331	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VSAL_I0332	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VSAL_I0333	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VSAL_I0334	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VSAL_I0335	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VSAL_I0336	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VSAL_I0337	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VSAL_I0338	COG1841	ribosomal large subunit assembly
VSAL_I0339	COG0200	Binds to the 23S rRNA
VSAL_I0340	COG0201	protein transport
VSAL_I0341	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VSAL_I0342	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VSAL_I0343	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VSAL_I0344	COG0202	RNA polymerase activity
VSAL_I0345	COG0203	ribosomal protein L17
VSAL_I0346	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VSAL_I0347	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VSAL_I0348	COG0163	prenyltransferase activity
VSAL_I0349	COG4143	(ABC) transporter
VSAL_I0350	COG1178	ABC-type Fe3 transport system permease component
VSAL_I0351	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VSAL_I0352	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VSAL_I0353	COG0564	pseudouridine synthase activity
VSAL_I0354	COG0589	response to stress
VSAL_I0358	COG1438	arginine binding
VSAL_I0359	COG0039	L-malate dehydrogenase activity
VSAL_I0360	COG0142	geranyltranstransferase activity
VSAL_I0361	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VSAL_I0362	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VSAL_I0363	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VSAL_I0364	COG2966	Psort location CytoplasmicMembrane, score
VSAL_I0365	COG3610	response to peptide
VSAL_I0367	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VSAL_I0368	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VSAL_I0369	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VSAL_I0370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VSAL_I0371	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VSAL_I0372	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VSAL_I0374	COG0066	3-isopropylmalate dehydratase activity
VSAL_I0375	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VSAL_I0376	COG0473	3-isopropylmalate dehydrogenase activity
VSAL_I0377	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VSAL_I0380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VSAL_I0382	COG0305	Participates in initiation and elongation during chromosome replication
VSAL_I0383	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VSAL_I0385	COG0166	Belongs to the GPI family
VSAL_I0387	COG0735	belongs to the Fur family
VSAL_I0391	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
VSAL_I0398	COG0582	viral genome integration into host DNA
VSAL_I0402	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VSAL_I0403	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VSAL_I0404	COG0175	sulfate reduction
VSAL_I0406	COG0545	Peptidyl-prolyl cis-trans isomerase
VSAL_I0407	COG3266	domain, Protein
VSAL_I0407	COG3061	Opacity-associated protein A
VSAL_I0409	COG2153	protein acetylation
VSAL_I0419	COG0737	Belongs to the 5'-nucleotidase family
VSAL_I0420	COG0175	sulfate reduction
VSAL_I0421	COG2895	sulfate adenylyltransferase (ATP) activity
VSAL_I0422	COG0471	metal ion transport
VSAL_I0422	COG3273	potassium ion transport
VSAL_I0423	COG0529	Catalyzes the synthesis of activated sulfate
VSAL_I0426	COG0577	efflux transmembrane transporter activity
VSAL_I0427	COG1136	(ABC) transporter
VSAL_I0430	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VSAL_I0432	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VSAL_I0433	COG0729	surface antigen
VSAL_I0434	COG2911	Protein conserved in bacteria
VSAL_I0437	COG4372	Transposase
VSAL_I0445	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VSAL_I0447	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VSAL_I0450	COG0297	glycogen (starch) synthase activity
VSAL_I0450	COG0438	transferase activity, transferring glycosyl groups
VSAL_I0451	COG0438	transferase activity, transferring glycosyl groups
VSAL_I0461	COG0629	single-stranded DNA binding
VSAL_I0465	COG2200	EAL domain
VSAL_I0465	COG2199	diguanylate cyclase activity
VSAL_I0470	COG3267	Type II secretory pathway component ExeA
VSAL_I0470	COG3409	Peptidoglycan-binding domain 1 protein
VSAL_I0477	COG4968	Prepilin-type N-terminal cleavage methylation domain
VSAL_I0483	COG1077	Cell shape determining protein MreB Mrl
VSAL_I0484	COG1792	Involved in formation and maintenance of cell shape
VSAL_I0485	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VSAL_I0486	COG0424	maF-like protein
VSAL_I0487	COG1530	ribonuclease E activity
VSAL_I0488	COG3164	Protein of unknown function
VSAL_I0489	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VSAL_I0490	COG0312	modulator of DNA gyrase
VSAL_I0492	COG0312	modulator of DNA gyrase
VSAL_I0493	COG2239	Acts as a magnesium transporter
VSAL_I0494	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSAL_I0495	COG1660	Displays ATPase and GTPase activities
VSAL_I0496	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSAL_I0499	COG1137	ATPase activity
VSAL_I0500	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VSAL_I0502	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
VSAL_I0503	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VSAL_I0503	COG0517	IMP dehydrogenase activity
VSAL_I0505	COG1127	ABC transporter
VSAL_I0506	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VSAL_I0507	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VSAL_I0508	COG2854	intermembrane phospholipid transfer
VSAL_I0510	COG5007	Belongs to the BolA IbaG family
VSAL_I0511	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VSAL_I0512	COG0204	Acyl-transferase
VSAL_I0517	COG0251	oxidation-reduction process
VSAL_I0518	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
VSAL_I0519	COG0540	Belongs to the ATCase OTCase family
VSAL_I0520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
VSAL_I0521	COG2235	arginine
VSAL_I0524	COG0525	valine-tRNA ligase activity
VSAL_I0525	COG2927	DNA polymerase III (CHI subunit)
VSAL_I0526	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VSAL_I0527	COG0795	lipopolysaccharide-transporting ATPase activity
VSAL_I0528	COG0795	lipopolysaccharide-transporting ATPase activity
VSAL_I0531	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VSAL_I0532	COG0741	lytic transglycosylase activity
VSAL_I0533	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VSAL_I0534	COG1194	a g-specific adenine glycosylase
VSAL_I0535	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VSAL_I0536	COG2066	Belongs to the glutaminase family
VSAL_I0537	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VSAL_I0538	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VSAL_I0540	COG1872	DUF167
VSAL_I0541	COG0762	integral membrane protein
VSAL_I0542	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VSAL_I0543	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VSAL_I0546	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VSAL_I0547	COG1678	Uncharacterized ACR, COG1678
VSAL_I0548	COG0189	ligase activity
VSAL_I0549	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VSAL_I0550	COG2356	endonuclease I
VSAL_I0551	COG3091	SprT-like family
VSAL_I0552	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VSAL_I0554	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VSAL_I0555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VSAL_I0556	COG0126	phosphoglycerate kinase activity
VSAL_I0557	COG0191	fructose-bisphosphate aldolase activity
VSAL_I0558	COG0513	Belongs to the DEAD box helicase family
VSAL_I0559	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
VSAL_I0561	COG0716	FMN binding
VSAL_I0564	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VSAL_I0566	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VSAL_I0567	COG2204	response regulator
VSAL_I0568	COG3066	DNA modification
VSAL_I0569	COG0494	nUDIX hydrolase
VSAL_I0571	COG0730	response to heat
VSAL_I0572	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VSAL_I0573	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
VSAL_I0574	COG1283	sodium-dependent phosphate transmembrane transporter activity
VSAL_I0575	COG0583	DNA-binding transcription factor activity
VSAL_I0576	COG0640	Transcriptional regulator
VSAL_I0577	COG0268	Binds directly to 16S ribosomal RNA
VSAL_I0578	COG0728	peptidoglycan biosynthetic process
VSAL_I0579	COG0196	riboflavin kinase activity
VSAL_I0580	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
VSAL_I0581	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VSAL_I0582	COG1047	Peptidyl-prolyl cis-trans
VSAL_I0583	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VSAL_I0584	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VSAL_I0585	COG0505	Belongs to the CarA family
VSAL_I0586	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VSAL_I0587	COG2027	D-alanyl-D-alanine carboxypeptidase
VSAL_I0588	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VSAL_I0589	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VSAL_I0590	COG1534	Rna-binding protein
VSAL_I0591	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VSAL_I0592	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VSAL_I0593	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VSAL_I0594	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VSAL_I0595	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VSAL_I0596	COG0779	Required for maturation of 30S ribosomal subunits
VSAL_I0597	COG0195	Participates in both transcription termination and antitermination
VSAL_I0598	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VSAL_I0599	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VSAL_I0600	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
VSAL_I0601	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VSAL_I0602	COG1185	polyribonucleotide nucleotidyltransferase activity
VSAL_I0612	COG0456	acetyltransferase
VSAL_I0613	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
VSAL_I0615	COG0084	hydrolase, TatD family'
VSAL_I0616	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VSAL_I0617	COG3385	transposase activity
VSAL_I0619	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VSAL_I0620	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VSAL_I0621	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VSAL_I0624	COG0560	Phosphoserine phosphatase
VSAL_I0626	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VSAL_I0627	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VSAL_I0628	COG4628	conserved protein (DUF2132)
VSAL_I0629	COG0402	S-adenosylhomocysteine deaminase activity
VSAL_I0630	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
VSAL_I0631	COG1022	Amp-dependent synthetase and ligase
VSAL_I0632	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VSAL_I0633	COG1546	Belongs to the CinA family
VSAL_I0634	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VSAL_I0635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VSAL_I0637	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VSAL_I0639	COG5016	pyruvate
VSAL_I0639	COG0511	ligase activity, forming carbon-carbon bonds
VSAL_I0640	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VSAL_I0641	COG1238	metal cluster binding
VSAL_I0642	COG0612	Peptidase, M16
VSAL_I0643	COG2918	glutathione biosynthetic process
VSAL_I0645	COG1854	S-ribosylhomocysteine lyase activity
VSAL_I0646	COG4536	flavin adenine dinucleotide binding
VSAL_I0647	COG4137	Cytochrome C assembly protein
VSAL_I0648	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VSAL_I0649	COG0228	four-way junction DNA binding
VSAL_I0650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VSAL_I0651	COG0336	Belongs to the RNA methyltransferase TrmD family
VSAL_I0652	COG0335	large ribosomal subunit rRNA binding
VSAL_I0653	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VSAL_I0654	COG0287	Prephenate dehydrogenase
VSAL_I0654	COG1605	Chorismate mutase
VSAL_I0655	COG0739	heme binding
VSAL_I0659	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VSAL_I0661	COG1605	Chorismate mutase
VSAL_I0661	COG0077	Prephenate dehydratase
VSAL_I0662	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VSAL_I0663	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VSAL_I0664	COG0564	pseudouridine synthase activity
VSAL_I0666	COG0542	response to heat
VSAL_I0672	COG2059	Chromate
VSAL_I0675	COG2171	N-acyltransferase activity
VSAL_I0676	COG3141	response to X-ray
VSAL_I0678	COG0583	DNA-binding transcription factor activity
VSAL_I0680	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VSAL_I0681	COG1074	ATP-dependent DNA helicase activity
VSAL_I0682	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VSAL_I0683	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VSAL_I0684	COG0165	Argininosuccinate lyase
VSAL_I0685	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VSAL_I0685	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VSAL_I0687	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VSAL_I0688	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VSAL_I0689	COG2166	iron-sulfur cluster assembly
VSAL_I0690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VSAL_I0691	COG0583	DNA-binding transcription factor activity
VSAL_I0692	COG2363	Small membrane protein
VSAL_I0693	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
VSAL_I0694	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VSAL_I0695	COG1611	Belongs to the LOG family
VSAL_I0696	COG3706	GGDEF domain
VSAL_I0698	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VSAL_I0698	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VSAL_I0700	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VSAL_I0701	COG1671	Belongs to the UPF0178 family
VSAL_I0704	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VSAL_I0705	COG2723	6-phospho-beta-galactosidase activity
VSAL_I0706	COG1940	carbohydrate kinase activity
VSAL_I0707	COG1447	Phosphotransferase system cellobiose-specific component IIA
VSAL_I0708	COG1609	Transcriptional regulator
VSAL_I0713	COG0564	pseudouridine synthase activity
VSAL_I0714	COG0483	inositol monophosphate 1-phosphatase activity
VSAL_I0715	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
VSAL_I0716	COG1959	2 iron, 2 sulfur cluster binding
VSAL_I0718	COG0822	iron-sulfur transferase activity
VSAL_I0720	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VSAL_I0721	COG0443	Heat shock 70 kDa protein
VSAL_I0722	COG0633	Ferredoxin
VSAL_I0723	COG2975	iron-sulfur cluster assembly
VSAL_I0725	COG0105	UTP biosynthetic process
VSAL_I0726	COG0820	rRNA (adenine-C2-)-methyltransferase activity
VSAL_I0729	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VSAL_I0730	COG0124	histidyl-tRNA synthetase
VSAL_I0731	COG2976	Protein conserved in bacteria
VSAL_I0732	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VSAL_I0733	COG1160	GTP binding
VSAL_I0736	COG1570	exodeoxyribonuclease VII activity
VSAL_I0737	COG0517	IMP dehydrogenase activity
VSAL_I0737	COG0516	GMP reductase activity
VSAL_I0738	COG0519	Catalyzes the synthesis of GMP from XMP
VSAL_I0738	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VSAL_I0739	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VSAL_I0740	COG2964	Protein conserved in bacteria
VSAL_I0741	COG3681	Belongs to the UPF0597 family
VSAL_I0742	COG0251	oxidation-reduction process
VSAL_I0746	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
VSAL_I0748	COG0590	tRNA wobble adenosine to inosine editing
VSAL_I0749	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VSAL_I0750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VSAL_I0750	COG0047	phosphoribosylformylglycinamidine synthase activity
VSAL_I0752	COG2991	Protein conserved in bacteria
VSAL_I0753	COG1342	Belongs to the UPF0251 family
VSAL_I0757	COG3469	chitinase activity
VSAL_I0757	COG3325	Belongs to the glycosyl hydrolase 18 family
VSAL_I0758	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VSAL_I0760	COG0189	ligase activity
VSAL_I0761	COG0189	ligase activity
VSAL_I0761	COG4067	protein conserved in archaea
VSAL_I0762	COG0733	neurotransmitter:sodium symporter activity
VSAL_I0777	COG3023	N-Acetylmuramoyl-L-alanine amidase
VSAL_I0783	COG4372	Transposase
VSAL_I0784	COG0012	GTP binding
VSAL_I0785	COG0193	aminoacyl-tRNA hydrolase activity
VSAL_I0786	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VSAL_I0787	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VSAL_I0788	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VSAL_I0789	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VSAL_I0790	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VSAL_I0791	COG2890	protein-(glutamine-N5) methyltransferase activity
VSAL_I0792	COG3094	Invasion gene expression up-regulator, SirB
VSAL_I0793	COG2912	Transglutaminase-like superfamily
VSAL_I0794	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VSAL_I0795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VSAL_I0795	COG1648	precorrin-2 dehydrogenase activity
VSAL_I0797	COG2146	nitrite reductase [NAD(P)H] activity
VSAL_I0798	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VSAL_I0802	COG2608	mercury ion transmembrane transporter activity
VSAL_I0802	COG2217	Heavy metal translocating P-type atpase
VSAL_I0803	COG0789	Transcriptional regulator
VSAL_I0804	COG3118	belongs to the thioredoxin family
VSAL_I0805	COG0300	oxidoreductase activity
VSAL_I0806	COG1090	epimerase
VSAL_I0807	COG0622	Phosphoesterase
VSAL_I0811	COG4372	Transposase
VSAL_I0814	COG0326	Molecular chaperone. Has ATPase activity
VSAL_I0815	COG0563	adenylate kinase activity
VSAL_I0816	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VSAL_I0817	COG0544	peptidyl-prolyl cis-trans isomerase activity
VSAL_I0818	COG0740	serine-type endopeptidase activity
VSAL_I0821	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VSAL_I0822	COG0776	regulation of translation
VSAL_I0823	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VSAL_I0824	COG1555	photosystem II stabilization
VSAL_I0824	COG1596	polysaccharide export
VSAL_I0825	COG3104	oligopeptide transport
VSAL_I0826	COG0250	Participates in transcription elongation, termination and antitermination
VSAL_I0827	COG0367	asparagine synthase
VSAL_I0828	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VSAL_I0828	COG4651	solute:proton antiporter activity
VSAL_I0829	COG1940	carbohydrate kinase activity
VSAL_I0829	COG1846	Transcriptional regulator
VSAL_I0830	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VSAL_I0831	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSAL_I0831	COG1263	PTS System
VSAL_I0831	COG2190	(PTS) system
VSAL_I0832	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VSAL_I0833	COG0735	belongs to the Fur family
VSAL_I0835	COG0716	FMN binding
VSAL_I0837	COG0596	Alpha beta hydrolase
VSAL_I0838	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VSAL_I0839	COG0033	Phosphoglucomutase
VSAL_I0840	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VSAL_I0841	COG0372	Belongs to the citrate synthase family
VSAL_I0842	COG2009	succinate dehydrogenase
VSAL_I0843	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VSAL_I0844	COG1053	succinate dehydrogenase
VSAL_I0846	COG0567	Dehydrogenase, E1 component
VSAL_I0847	COG0508	dehydrogenase complex catalyzes the overall conversion of
VSAL_I0848	COG0045	succinate-CoA ligase (ADP-forming) activity
VSAL_I0850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VSAL_I0851	COG1121	(ABC) transporter
VSAL_I0852	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VSAL_I0853	COG0739	heme binding
VSAL_I0855	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VSAL_I0856	COG1032	radical SAM domain protein
VSAL_I0857	COG3069	C4-dicarboxylate transmembrane transporter activity
VSAL_I0860	COG0583	DNA-binding transcription factor activity
VSAL_I0864	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VSAL_I0868	COG0444	Belongs to the ABC transporter superfamily
VSAL_I0869	COG0747	negative chemotaxis
VSAL_I0870	COG4239	(ABC) transporter, permease
VSAL_I0871	COG4174	ABC transporter (Permease)
VSAL_I0875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VSAL_I0877	COG1012	belongs to the aldehyde dehydrogenase family
VSAL_I0879	COG0583	DNA-binding transcription factor activity
VSAL_I0885	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VSAL_I0886	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VSAL_I0887	COG2011	ABC-type metal ion transport system permease component
VSAL_I0888	COG1464	Belongs to the NlpA lipoprotein family
VSAL_I0889	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VSAL_I0890	COG0254	rRNA binding
VSAL_I0891	COG1720	tRNA m6t6A37 methyltransferase activity
VSAL_I0892	COG0442	prolyl-tRNA aminoacylation
VSAL_I0893	COG2731	YhcH YjgK YiaL family protein
VSAL_I0898	COG1737	Transcriptional regulator
VSAL_I0899	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VSAL_I0910	COG1214	PFAM Peptidase M22, glycoprotease
VSAL_I0911	COG1199	ATP-dependent helicase activity
VSAL_I0912	COG0788	formyltetrahydrofolate deformylase activity
VSAL_I0913	COG0596	Alpha beta hydrolase
VSAL_I0915	COG0401	homolog of Blt101
VSAL_I0920	COG0840	transmembrane signaling receptor activity
VSAL_I0921	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VSAL_I0922	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VSAL_I0922	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VSAL_I0925	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VSAL_I0926	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VSAL_I0927	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VSAL_I0928	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VSAL_I0930	COG0784	Response regulator, receiver
VSAL_I0930	COG2205	protein histidine kinase activity
VSAL_I0933	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VSAL_I0934	COG0142	geranyltranstransferase activity
VSAL_I0935	COG1722	exodeoxyribonuclease VII activity
VSAL_I0936	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VSAL_I0938	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VSAL_I0938	COG0301	tRNA thio-modification
VSAL_I0941	COG0693	protein deglycase activity
VSAL_I0942	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VSAL_I0944	COG2807	transmembrane transport
VSAL_I0945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VSAL_I0947	COG2813	Specifically methylates the guanine in position
VSAL_I0948	COG0271	Belongs to the BolA IbaG family
VSAL_I0949	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VSAL_I0953	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VSAL_I0955	COG1477	protein flavinylation
VSAL_I0956	COG2991	Protein conserved in bacteria
VSAL_I0957	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VSAL_I0965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VSAL_I0973	COG2195	Cleaves the N-terminal amino acid of tripeptides
VSAL_I0974	COG2252	PERMEase
VSAL_I0975	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VSAL_I0977	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VSAL_I0978	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VSAL_I0979	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VSAL_I0980	COG0321	lipoyl(octanoyl) transferase activity
VSAL_I0981	COG2921	Belongs to the UPF0250 family
VSAL_I0982	COG1686	Belongs to the peptidase S11 family
VSAL_I0983	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VSAL_I0984	COG0772	Belongs to the SEDS family
VSAL_I0985	COG0768	penicillin binding
VSAL_I0986	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VSAL_I0987	COG0799	negative regulation of ribosome biogenesis
VSAL_I0988	COG1466	dna polymerase III delta subunit
VSAL_I0990	COG0495	leucyl-tRNA aminoacylation
VSAL_I0991	COG2888	peptidyl-tyrosine sulfation
VSAL_I0992	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VSAL_I0993	COG4535	Mg2 and Co2 transporter CorC
VSAL_I0994	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VSAL_I0995	COG1702	phosphate starvation-inducible protein PhoH
VSAL_I0996	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VSAL_I0997	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VSAL_I1007	COG2983	Belongs to the UPF0260 family
VSAL_I1008	COG4974	Belongs to the 'phage' integrase family
VSAL_I1025	COG4695	Portal protein
VSAL_I1045	COG5301	cellulose 1,4-beta-cellobiosidase activity
VSAL_I1055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VSAL_I1057	COG3083	sulfuric ester hydrolase activity
VSAL_I1058	COG3082	Protein of unknown function (DUF1414)
VSAL_I1059	COG3081	Nucleoid-associated protein
VSAL_I1061	COG4372	Transposase
VSAL_I1064	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VSAL_I1065	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VSAL_I1066	COG2894	cell division
VSAL_I1067	COG0850	regulation of cytokinetic process
VSAL_I1068	COG3100	YcgL domain-containing protein
VSAL_I1069	COG2951	lytic endotransglycosylase activity
VSAL_I1070	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VSAL_I1070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VSAL_I1071	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VSAL_I1072	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VSAL_I1073	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VSAL_I1075	COG0101	tRNA pseudouridine synthase activity
VSAL_I1077	COG0285	dihydrofolate synthase activity
VSAL_I1078	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VSAL_I1079	COG1286	toxin biosynthetic process
VSAL_I1080	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VSAL_I1081	COG0583	DNA-binding transcription factor activity
VSAL_I1082	COG0745	RESPONSE REGULATOR receiver
VSAL_I1083	COG2832	Protein of unknown function (DUF454)
VSAL_I1084	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VSAL_I1085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
VSAL_I1086	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VSAL_I1087	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VSAL_I1091	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VSAL_I1093	COG0697	spore germination
VSAL_I1094	COG1979	alcohol dehydrogenase
VSAL_I1095	COG2207	Transcriptional regulator
VSAL_I1096	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
VSAL_I1097	COG0436	Aminotransferase
VSAL_I1098	COG1169	isochorismate synthase
VSAL_I1099	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VSAL_I1101	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
VSAL_I1102	COG1441	menaquinone biosynthetic process
VSAL_I1127	COG3923	Primosomal replication protein n
VSAL_I1128	COG0730	response to heat
VSAL_I1129	COG1199	ATP-dependent helicase activity
VSAL_I1131	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VSAL_I1133	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VSAL_I1134	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VSAL_I1135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VSAL_I1136	COG0131	Imidazoleglycerol-phosphate dehydratase
VSAL_I1136	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VSAL_I1137	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VSAL_I1138	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VSAL_I1139	COG0107	imidazoleglycerol-phosphate synthase activity
VSAL_I1140	COG0140	phosphoribosyl-ATP diphosphatase activity
VSAL_I1140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VSAL_I1142	COG0564	pseudouridine synthase activity
VSAL_I1143	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VSAL_I1143	COG0116	Belongs to the methyltransferase superfamily
VSAL_I1145	COG2350	Protein conserved in bacteria
VSAL_I1146	COG1607	acyl-coa hydrolase
VSAL_I1147	COG2917	probably involved in intracellular septation
VSAL_I1149	COG0159	tryptophan synthase activity
VSAL_I1150	COG0133	tryptophan synthase activity
VSAL_I1151	COG0135	phosphoribosylanthranilate isomerase activity
VSAL_I1151	COG0134	indole-3-glycerol-phosphate synthase activity
VSAL_I1152	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VSAL_I1153	COG0512	Glutamine amidotransferase of anthranilate synthase
VSAL_I1154	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VSAL_I1155	COG0613	PHP domain protein
VSAL_I1156	COG0009	L-threonylcarbamoyladenylate synthase
VSAL_I1159	COG1187	pseudouridine synthase activity
VSAL_I1160	COG1028	Short-chain dehydrogenase reductase Sdr
VSAL_I1161	COG0616	signal peptide processing
VSAL_I1164	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VSAL_I1184	COG3385	transposase activity
VSAL_I1186	COG1280	lysine exporter protein (LysE YggA)
VSAL_I1187	COG2207	Transcriptional regulator
VSAL_I1187	COG1917	Cupin 2, conserved barrel domain protein
VSAL_I1190	COG0179	Fumarylacetoacetate (FAA) hydrolase
VSAL_I1193	COG2195	Cleaves the N-terminal amino acid of tripeptides
VSAL_I1194	COG3069	C4-dicarboxylate transmembrane transporter activity
VSAL_I1197	COG0076	glutamate decarboxylase activity
VSAL_I1198	COG2985	domain, Protein
VSAL_I1199	COG0583	DNA-binding transcription factor activity
VSAL_I1200	COG1741	Belongs to the pirin family
VSAL_I1201	COG0435	Glutathione S-transferase
VSAL_I1204	COG4667	esterase of the alpha-beta hydrolase superfamily
VSAL_I1205	COG4372	Transposase
VSAL_I1210	COG0673	inositol 2-dehydrogenase activity
VSAL_I1211	COG4533	DNA binding
VSAL_I1216	COG3655	Transcriptional regulator
VSAL_I1227	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VSAL_I1233	COG0583	DNA-binding transcription factor activity
VSAL_I1234	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VSAL_I1242	COG1309	transcriptional regulator
VSAL_I1244	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VSAL_I1247	COG1403	HNH endonuclease
VSAL_I1252	COG0583	DNA-binding transcription factor activity
VSAL_I1254	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VSAL_I1260	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VSAL_I1262	COG4681	YaeQ
VSAL_I1264	COG0583	DNA-binding transcription factor activity
VSAL_I1271	COG0745	RESPONSE REGULATOR receiver
VSAL_I1271	COG3706	GGDEF domain
VSAL_I1272	COG2949	membrane
VSAL_I1274	COG0281	malic enzyme
VSAL_I1280	COG4372	Transposase
VSAL_I1281	COG1301	dicarboxylic acid transport
VSAL_I1282	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VSAL_I1289	COG0366	Alpha amylase catalytic
VSAL_I1293	COG4372	Transposase
VSAL_I1294	COG0840	transmembrane signaling receptor activity
VSAL_I1295	COG0537	adenosine 5'-monophosphoramidase activity
VSAL_I1302	COG2226	methyltransferase
VSAL_I1304	COG2084	Dehydrogenase
VSAL_I1305	COG2175	clavaminate synthase activity
VSAL_I1306	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VSAL_I1311	COG1252	NADH dehydrogenase
VSAL_I1312	COG0513	Belongs to the DEAD box helicase family
VSAL_I1318	COG3279	Response regulator of the LytR AlgR family
VSAL_I1319	COG3275	phosphorelay sensor kinase activity
VSAL_I1320	COG1584	GPR1 FUN34 yaaH family protein
VSAL_I1322	COG0501	Belongs to the peptidase M48B family
VSAL_I1325	COG1301	dicarboxylic acid transport
VSAL_I1326	COG0402	S-adenosylhomocysteine deaminase activity
VSAL_I1327	COG2989	Protein conserved in bacteria
VSAL_I1328	COG3108	Peptidase M15
VSAL_I1329	COG0017	Asparaginyl-tRNA synthetase
VSAL_I1330	COG0720	synthase
VSAL_I1332	COG0420	3'-5' exonuclease activity
VSAL_I1333	COG0419	ATPase involved in DNA repair
VSAL_I1337	COG0814	amino acid
VSAL_I1343	COG1760	l-serine dehydratase
VSAL_I1344	COG0814	amino acid
VSAL_I1349	COG3385	transposase activity
VSAL_I1352	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VSAL_I1355	COG0626	cystathionine gamma-synthase activity
VSAL_I1358	COG3501	Rhs element vgr protein
VSAL_I1366	COG1793	dna ligase
VSAL_I1367	COG1609	Transcriptional regulator
VSAL_I1368	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VSAL_I1369	COG1879	ABC-type sugar transport system periplasmic component
VSAL_I1370	COG1172	Belongs to the binding-protein-dependent transport system permease family
VSAL_I1371	COG1129	ABC transporter
VSAL_I1372	COG1869	D-ribose catabolic process
VSAL_I1382	COG0534	Mate efflux family protein
VSAL_I1383	COG0307	riboflavin synthase, alpha
VSAL_I1387	COG0791	NLP P60 protein
VSAL_I1388	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VSAL_I1389	COG1187	pseudouridine synthase activity
VSAL_I1392	COG1940	carbohydrate kinase activity
VSAL_I1393	COG0653	protein targeting
VSAL_I1397	COG0303	'Molybdopterin
VSAL_I1398	COG0746	molybdenum cofactor guanylyltransferase activity
VSAL_I1399	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VSAL_I1400	COG4662	Binding-protein-dependent transport system inner membrane component
VSAL_I1403	COG3852	Histidine kinase
VSAL_I1404	COG0346	lactoylglutathione lyase activity
VSAL_I1408	COG0586	Pfam SNARE associated Golgi protein
VSAL_I1417	COG4372	Transposase
VSAL_I1421	COG2897	thiosulfate sulfurtransferase activity
VSAL_I1435	COG4336	lyase activity
VSAL_I1436	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VSAL_I1437	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
VSAL_I1438	COG1984	allophanate hydrolase subunit 2
VSAL_I1442	COG4372	Transposase
VSAL_I1443	COG1914	H( )-stimulated, divalent metal cation uptake system
VSAL_I1448	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VSAL_I1453	COG3383	formate dehydrogenase (NAD+) activity
VSAL_I1453	COG0243	molybdopterin cofactor binding
VSAL_I1454	COG0437	4 iron, 4 sulfur cluster binding
VSAL_I1456	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VSAL_I1469	COG2026	Addiction module toxin, RelE StbE family
VSAL_I1473	COG0456	acetyltransferase
VSAL_I1482	COG1028	Short-chain dehydrogenase reductase Sdr
VSAL_I1484	COG4221	oxidoreductase activity
VSAL_I1485	COG2258	MOSC domain
VSAL_I1494	COG0456	acetyltransferase
VSAL_I1494	COG0454	-acetyltransferase
VSAL_I1501	COG3394	polysaccharide catabolic process
VSAL_I1504	COG0110	maltose O-acetyltransferase activity
VSAL_I1506	COG0384	phenazine biosynthesis protein PhzF
VSAL_I1507	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VSAL_I1508	COG2226	methyltransferase
VSAL_I1513	COG1418	mRNA catabolic process
VSAL_I1514	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VSAL_I1516	COG0534	Mate efflux family protein
VSAL_I1517	COG0500	methyltransferase
VSAL_I1527	COG1309	transcriptional regulator
VSAL_I1532	COG0402	S-adenosylhomocysteine deaminase activity
VSAL_I1536	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VSAL_I1538	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VSAL_I1538	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
VSAL_I1539	COG3008	intermembrane lipid transfer
VSAL_I1540	COG2995	paraquat-inducible protein a
VSAL_I1541	COG1132	(ABC) transporter
VSAL_I1542	COG1956	GAF domain-containing protein
VSAL_I1543	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VSAL_I1549	COG0167	dihydroorotate dehydrogenase activity
VSAL_I1551	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VSAL_I1551	COG0116	Belongs to the methyltransferase superfamily
VSAL_I1556	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VSAL_I1557	COG1067	ATP-dependent peptidase activity
VSAL_I1558	COG3120	sequence-specific DNA binding
VSAL_I1563	COG3278	Belongs to the heme-copper respiratory oxidase family
VSAL_I1566	COG2010	Cytochrome c
VSAL_I1568	COG2217	Heavy metal translocating P-type atpase
VSAL_I1571	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VSAL_I1572	COG0589	response to stress
VSAL_I1573	COG0037	tRNA processing
VSAL_I1576	COG4372	Transposase
VSAL_I1580	COG3842	ATPase activity
VSAL_I1581	COG1176	ABC-type spermidine putrescine transport system, permease component I
VSAL_I1582	COG1177	transmembrane transport
VSAL_I1583	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VSAL_I1584	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VSAL_I1585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VSAL_I1586	COG0583	DNA-binding transcription factor activity
VSAL_I1587	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VSAL_I1594	COG0494	nUDIX hydrolase
VSAL_I1608	COG1609	Transcriptional regulator
VSAL_I1609	COG1757	Na H antiporter
VSAL_I1610	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
VSAL_I1611	COG1917	Cupin 2, conserved barrel domain protein
VSAL_I1611	COG2207	Transcriptional regulator
VSAL_I1612	COG0697	spore germination
VSAL_I1614	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
VSAL_I1615	COG1263	PTS System
VSAL_I1615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSAL_I1618	COG1609	Transcriptional regulator
VSAL_I1624	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VSAL_I1635	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
VSAL_I1636	COG0840	transmembrane signaling receptor activity
VSAL_I1645	COG2944	sequence-specific DNA binding
VSAL_I1646	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
VSAL_I1656	COG4372	Transposase
VSAL_I1658	COG1446	asparaginase
VSAL_I1659	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VSAL_I1660	COG1447	Phosphotransferase system cellobiose-specific component IIA
VSAL_I1664	COG4372	Transposase
VSAL_I1668	COG0071	Belongs to the small heat shock protein (HSP20) family
VSAL_I1669	COG0443	Heat shock 70 kDa protein
VSAL_I1672	COG4372	Transposase
VSAL_I1674	COG0484	heat shock protein binding
VSAL_I1676	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VSAL_I1680	COG2925	Exonuclease
VSAL_I1685	COG0154	amidase activity
VSAL_I1686	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
VSAL_I1687	COG1448	Aminotransferase
VSAL_I1689	COG0583	DNA-binding transcription factor activity
VSAL_I1696	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VSAL_I1698	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VSAL_I1700	COG1643	Atp-dependent helicase
VSAL_I1701	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
VSAL_I1701	COG2885	chlorophyll binding
VSAL_I1706	COG1254	Belongs to the acylphosphatase family
VSAL_I1709	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VSAL_I1712	COG0584	glycerophosphoryl diester phosphodiesterase
VSAL_I1713	COG2271	Major facilitator Superfamily
VSAL_I1721	COG0582	viral genome integration into host DNA
VSAL_I1726	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VSAL_I1727	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VSAL_I1728	COG1666	GTP binding
VSAL_I1731	COG0776	regulation of translation
VSAL_I1732	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VSAL_I1732	COG0072	phenylalanine-tRNA ligase activity
VSAL_I1733	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VSAL_I1747	COG4372	Transposase
VSAL_I1748	COG0748	coenzyme F420 binding
VSAL_I1749	COG3721	Heme iron utilization protein
VSAL_I1752	COG0811	peptide transport
VSAL_I1753	COG0848	biopolymer transport protein
VSAL_I1755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VSAL_I1756	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VSAL_I1757	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VSAL_I1758	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VSAL_I1759	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
VSAL_I1760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
VSAL_I1761	COG4326	sporulation control protein
VSAL_I1764	COG0443	Heat shock 70 kDa protein
VSAL_I1768	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VSAL_I1769	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VSAL_I1774	COG0814	amino acid
VSAL_I1776	COG3385	transposase activity
VSAL_I1780	COG4372	Transposase
VSAL_I1782	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VSAL_I1787	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VSAL_I1788	COG1454	alcohol dehydrogenase
VSAL_I1790	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VSAL_I1796	COG1115	amino acid carrier protein
VSAL_I1797	COG0668	transmembrane transport
VSAL_I1798	COG1280	lysine exporter protein (LysE YggA)
VSAL_I1800	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VSAL_I1801	COG1396	sequence-specific DNA binding
VSAL_I1802	COG3550	peptidyl-serine autophosphorylation
VSAL_I1806	COG3046	protein related to deoxyribodipyrimidine photolyase
VSAL_I1807	COG0625	glutathione transferase activity
VSAL_I1814	COG0500	methyltransferase
VSAL_I1815	COG1213	nucleotidyl transferase
VSAL_I1817	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VSAL_I1824	COG3706	GGDEF domain
VSAL_I1827	COG0443	Heat shock 70 kDa protein
VSAL_I1831	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VSAL_I1836	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VSAL_I1837	COG4988	ABC transporter
VSAL_I1838	COG0492	ferredoxin-NADP+ reductase activity
VSAL_I1839	COG0686	Belongs to the AlaDH PNT family
VSAL_I1840	COG1522	sequence-specific DNA binding
VSAL_I1842	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VSAL_I1843	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VSAL_I1844	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VSAL_I1845	COG3118	belongs to the thioredoxin family
VSAL_I1846	COG3099	Belongs to the UPF0263 family
VSAL_I1847	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VSAL_I1849	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VSAL_I1850	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VSAL_I1852	COG3139	Protein of unknown function (DUF1315)
VSAL_I1854	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VSAL_I1855	COG1454	alcohol dehydrogenase
VSAL_I1855	COG1012	belongs to the aldehyde dehydrogenase family
VSAL_I1859	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VSAL_I1861	COG2056	Na+-H+ antiporter family
VSAL_I1862	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VSAL_I1865	COG0346	lactoylglutathione lyase activity
VSAL_I1866	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VSAL_I1867	COG4660	Part of a membrane complex involved in electron transport
VSAL_I1868	COG4659	FMN binding
VSAL_I1869	COG4658	electron transport chain
VSAL_I1870	COG4656	Part of a membrane complex involved in electron transport
VSAL_I1871	COG2878	Part of a membrane complex involved in electron transport
VSAL_I1872	COG4657	Part of a membrane complex involved in electron transport
VSAL_I1873	COG0556	nucleotide-excision repair
VSAL_I1874	COG2204	response regulator
VSAL_I1875	COG2198	Histidine kinase
VSAL_I1876	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VSAL_I1877	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VSAL_I1878	COG0315	cyclic pyranopterin monophosphate synthase activity
VSAL_I1879	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VSAL_I1880	COG0314	molybdopterin synthase activity
VSAL_I1883	COG4067	protein conserved in archaea
VSAL_I1883	COG0189	ligase activity
VSAL_I1884	COG0500	methyltransferase
VSAL_I1885	COG4106	trans-aconitate 2-methyltransferase activity
VSAL_I1886	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VSAL_I1887	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VSAL_I1888	COG0632	four-way junction helicase activity
VSAL_I1889	COG2255	four-way junction helicase activity
VSAL_I1890	COG1271	oxidase subunit
VSAL_I1891	COG1294	oxidase, subunit
VSAL_I1892	COG4890	Cyd operon protein YbgT
VSAL_I1894	COG0824	Thioesterase
VSAL_I1895	COG0811	peptide transport
VSAL_I1898	COG0823	Involved in the tonB-independent uptake of proteins
VSAL_I1899	COG2885	chlorophyll binding
VSAL_I1900	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
VSAL_I1901	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VSAL_I1903	COG0662	Cupin 2, conserved barrel domain protein
VSAL_I1903	COG2207	Transcriptional regulator
VSAL_I1904	COG1566	PFAM secretion protein HlyD family protein
VSAL_I1906	COG0628	permease
VSAL_I1914	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VSAL_I1915	COG2153	protein acetylation
VSAL_I1918	COG2814	Major facilitator Superfamily
VSAL_I1920	COG0697	spore germination
VSAL_I1924	COG5295	Hep Hag repeat protein
VSAL_I1925	COG1475	DNA binding
VSAL_I1930	COG4372	Transposase
VSAL_I1931	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VSAL_I1932	COG0303	'Molybdopterin
VSAL_I1933	COG0302	gtp cyclohydrolase
VSAL_I1935	COG0733	neurotransmitter:sodium symporter activity
VSAL_I1936	COG3012	SEC-C Motif Domain Protein
VSAL_I1937	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VSAL_I1938	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VSAL_I1939	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VSAL_I1940	COG0215	cysteine-tRNA ligase activity
VSAL_I1941	COG1435	thymidine kinase activity
VSAL_I1948	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VSAL_I1949	COG0444	Belongs to the ABC transporter superfamily
VSAL_I1951	COG0840	transmembrane signaling receptor activity
VSAL_I1952	COG2850	peptidyl-arginine hydroxylation
VSAL_I1953	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VSAL_I1954	COG3385	transposase activity
VSAL_I1955	COG1882	Formate acetyltransferase
VSAL_I1956	COG2116	formate transmembrane transporter activity
VSAL_I1959	COG4215	(ABC) transporter
VSAL_I1961	COG2999	glutathione oxidoreductase activity
VSAL_I1962	COG0708	Exodeoxyribonuclease III
VSAL_I1963	COG1566	PFAM secretion protein HlyD family protein
VSAL_I1965	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VSAL_I1967	COG1522	sequence-specific DNA binding
VSAL_I1968	COG1946	Acyl-CoA thioesterase
VSAL_I1969	COG3126	Type III secretion system lipoprotein chaperone (YscW)
VSAL_I1972	COG0803	Belongs to the bacterial solute-binding protein 9 family
VSAL_I1973	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VSAL_I1976	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
VSAL_I1977	COG3706	GGDEF domain
VSAL_I1978	COG2205	protein histidine kinase activity
VSAL_I1979	COG0745	RESPONSE REGULATOR receiver
VSAL_I1982	COG3070	regulator of competence-specific genes
VSAL_I1983	COG1609	Transcriptional regulator
VSAL_I1984	COG3381	protein complex oligomerization
VSAL_I1985	COG0745	RESPONSE REGULATOR receiver
VSAL_I1988	COG4720	Psort location CytoplasmicMembrane, score
VSAL_I1995	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
VSAL_I1997	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
VSAL_I1999	COG0437	4 iron, 4 sulfur cluster binding
VSAL_I2000	COG3301	Polysulphide reductase, NrfD
VSAL_I2001	COG1138	Cytochrome C-type biogenesis protein
VSAL_I2003	COG3088	subunit of a heme lyase
VSAL_I2003	COG4235	cytochrome complex assembly
VSAL_I2005	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VSAL_I2006	COG0583	DNA-binding transcription factor activity
VSAL_I2007	COG0671	phosphoesterase, PA-phosphatase related
VSAL_I2019	COG2814	Major facilitator Superfamily
VSAL_I2022	COG0534	Mate efflux family protein
VSAL_I2023	COG1136	(ABC) transporter
VSAL_I2026	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VSAL_I2027	COG3385	transposase activity
VSAL_I2028	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VSAL_I2029	COG2985	domain, Protein
VSAL_I2029	COG0569	domain protein
VSAL_I2030	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VSAL_I2031	COG1737	Transcriptional regulator
VSAL_I2032	COG0076	glutamate decarboxylase activity
VSAL_I2034	COG2431	L-lysine efflux transmembrane transporter activity
VSAL_I2042	COG4372	Transposase
VSAL_I2047	COG1051	belongs to the nudix hydrolase family
VSAL_I2053	COG0670	Belongs to the BI1 family
VSAL_I2054	COG1126	abc transporter atp-binding protein
VSAL_I2055	COG0765	amino acid transport
VSAL_I2056	COG4597	amino acid ABC transporter
VSAL_I2057	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VSAL_I2058	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VSAL_I2058	COG1648	precorrin-2 dehydrogenase activity
VSAL_I2059	COG2188	Transcriptional regulator
VSAL_I2062	COG0277	FAD linked oxidase domain protein
VSAL_I2062	COG0247	lactate metabolic process
VSAL_I2064	COG1125	glycine betaine transport
VSAL_I2064	COG0517	IMP dehydrogenase activity
VSAL_I2066	COG3344	reverse transcriptase
VSAL_I2067	COG2217	Heavy metal translocating P-type atpase
VSAL_I2068	COG3437	response regulator, receiver
VSAL_I2075	COG0840	transmembrane signaling receptor activity
VSAL_I2076	COG2258	MOSC domain
VSAL_I2078	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VSAL_I2081	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VSAL_I2082	COG1061	Type III restriction enzyme res subunit
VSAL_I2084	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VSAL_I2090	COG1028	Short-chain dehydrogenase reductase Sdr
VSAL_I2092	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VSAL_I2096	COG0824	Thioesterase
VSAL_I2099	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VSAL_I2102	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VSAL_I2103	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VSAL_I2109	COG3102	Protein conserved in bacteria
VSAL_I2110	COG0018	arginyl-trna synthetase
VSAL_I2111	COG3092	negative regulation of chromosome organization
VSAL_I2112	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VSAL_I2113	COG0280	phosphate acetyltransferase
VSAL_I2113	COG0857	belongs to the CobB CobQ family
VSAL_I2114	COG4372	Transposase
VSAL_I2118	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VSAL_I2119	COG0573	inorganic phosphate transmembrane transporter activity
VSAL_I2120	COG0581	inorganic phosphate transmembrane transporter activity
VSAL_I2121	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VSAL_I2129	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VSAL_I2132	COG1879	ABC-type sugar transport system periplasmic component
VSAL_I2133	COG1803	Methylglyoxal synthase
VSAL_I2134	COG0210	DNA helicase
VSAL_I2135	COG1289	transmembrane transporter activity
VSAL_I2136	COG0019	diaminopimelate decarboxylase activity
VSAL_I2140	COG0322	excinuclease ABC activity
VSAL_I2141	COG2197	response regulator
VSAL_I2142	COG0417	DNA replication proofreading
VSAL_I2144	COG1757	Na H antiporter
VSAL_I2146	COG3713	MltA-interacting MipA family protein
VSAL_I2148	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VSAL_I2149	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VSAL_I2152	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VSAL_I2153	COG3706	GGDEF domain
VSAL_I2155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VSAL_I2156	COG0446	pyridine nucleotide-disulphide oxidoreductase
VSAL_I2156	COG1902	pentaerythritol trinitrate reductase activity
VSAL_I2157	COG0616	signal peptide processing
VSAL_I2158	COG0252	asparaginase activity
VSAL_I2159	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VSAL_I2163	COG4372	Transposase
VSAL_I2165	COG2062	phosphohistidine phosphatase, SixA
VSAL_I2166	COG2840	Smr protein MutS2
VSAL_I2167	COG2890	protein-(glutamine-N5) methyltransferase activity
VSAL_I2168	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VSAL_I2169	COG2860	membrane
VSAL_I2170	COG1285	pathogenesis
VSAL_I2171	COG3101	peptidyl-lysine hydroxylation
VSAL_I2173	COG3706	GGDEF domain
VSAL_I2175	COG1560	Kdo2-lipid A biosynthetic process
VSAL_I2176	COG0038	chloride channel
VSAL_I2178	COG4372	Transposase
VSAL_I2181	COG2226	methyltransferase
VSAL_I2182	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VSAL_I2183	COG3013	Belongs to the UPF0304 family
VSAL_I2184	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VSAL_I2186	COG4565	transcriptional regulatory protein
VSAL_I2187	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VSAL_I2189	COG0513	Belongs to the DEAD box helicase family
VSAL_I2195	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VSAL_I2196	COG2915	High frequency lysogenization protein hflD homolog
VSAL_I2198	COG3604	Transcriptional regulator
VSAL_I2199	COG1773	rubredoxin
VSAL_I2199	COG0426	domain, Protein
VSAL_I2200	COG0446	pyridine nucleotide-disulphide oxidoreductase
VSAL_I2201	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VSAL_I2204	COG1187	pseudouridine synthase activity
VSAL_I2206	COG2719	SpoVR family
VSAL_I2207	COG2718	Belongs to the UPF0229 family
VSAL_I2208	COG2766	serine protein kinase
VSAL_I2209	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VSAL_I2210	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VSAL_I2212	COG1278	Cold shock
VSAL_I2213	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VSAL_I2214	COG0542	response to heat
VSAL_I2215	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VSAL_I2217	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VSAL_I2218	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
VSAL_I2219	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VSAL_I2220	COG0539	negative regulation of cytoplasmic translation
VSAL_I2222	COG0776	regulation of translation
VSAL_I2223	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VSAL_I2224	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VSAL_I2225	COG0284	orotidine-5'-phosphate decarboxylase activity
VSAL_I2226	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VSAL_I2226	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VSAL_I2227	COG0489	protein tyrosine kinase activity
VSAL_I2228	COG0572	uridine kinase
VSAL_I2230	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VSAL_I2231	COG2770	Histidine kinase
VSAL_I2231	COG3437	response regulator, receiver
VSAL_I2232	COG0659	secondary active sulfate transmembrane transporter activity
VSAL_I2233	COG1530	ribonuclease E activity
VSAL_I2234	COG0564	pseudouridine synthase activity
VSAL_I2235	COG0424	maF-like protein
VSAL_I2236	COG1399	metal-binding, possibly nucleic acid-binding protein
VSAL_I2237	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VSAL_I2238	COG0416	fatty acid biosynthetic process
VSAL_I2239	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VSAL_I2243	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VSAL_I2244	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VSAL_I2245	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VSAL_I2246	COG0470	DNA polymerase III
VSAL_I2247	COG0084	hydrolase, TatD family'
VSAL_I2250	COG4372	Transposase
VSAL_I2252	COG1263	PTS System
VSAL_I2252	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSAL_I2254	COG0733	neurotransmitter:sodium symporter activity
VSAL_I2258	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
VSAL_I2262	COG4372	Transposase
VSAL_I2264	COG4372	Transposase
VSAL_I2267	COG1024	Enoyl-CoA hydratase
VSAL_I2267	COG1250	3-hydroxyacyl-CoA dehydrogenase
VSAL_I2269	COG2067	long-chain fatty acid transport protein
VSAL_I2272	COG2853	Lipoprotein
VSAL_I2275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VSAL_I2276	COG1138	Cytochrome C-type biogenesis protein
VSAL_I2277	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VSAL_I2278	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VSAL_I2279	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VSAL_I2280	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VSAL_I2281	COG4133	protoheme IX ABC transporter activity
VSAL_I2283	COG0835	chemotaxis
VSAL_I2285	COG1192	Involved in chromosome partitioning
VSAL_I2286	COG2201	protein-glutamate methylesterase activity
VSAL_I2287	COG0643	Histidine kinase
VSAL_I2287	COG2198	Histidine kinase
VSAL_I2288	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VSAL_I2291	COG0455	bacterial-type flagellum organization
VSAL_I2296	COG1684	flagellar biosynthetic protein fliR
VSAL_I2297	COG1987	bacterial-type flagellum assembly
VSAL_I2307	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VSAL_I2310	COG2204	response regulator
VSAL_I2311	COG4191	Histidine kinase
VSAL_I2313	COG1516	flagellar protein fliS
VSAL_I2315	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VSAL_I2317	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VSAL_I2318	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VSAL_I2319	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VSAL_I2325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VSAL_I2330	COG1705	Flagellar rod assembly protein muramidase FlgJ
VSAL_I2330	COG3951	Flagellar rod assembly protein muramidase FlgJ
VSAL_I2331	COG1706	bacterial-type flagellum-dependent cell motility
VSAL_I2332	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VSAL_I2333	COG4786	Flagellar basal body rod
VSAL_I2334	COG4787	bacterial-type flagellum-dependent cell motility
VSAL_I2336	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
VSAL_I2337	COG1558	bacterial-type flagellum-dependent cell motility
VSAL_I2338	COG1815	bacterial-type flagellum-dependent cell motility
VSAL_I2340	COG0784	Response regulator, receiver
VSAL_I2340	COG0835	chemotaxis
VSAL_I2342	COG2747	anti-sigma28 factor FlgM
VSAL_I2348	COG3706	GGDEF domain
VSAL_I2350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VSAL_I2353	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VSAL_I2354	COG3115	cell septum assembly
VSAL_I2356	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VSAL_I2357	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSAL_I2358	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VSAL_I2359	COG2190	(PTS) system
VSAL_I2360	COG2837	iron assimilation
VSAL_I2364	COG3005	denitrification pathway
VSAL_I2368	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VSAL_I2369	COG3850	Histidine kinase
VSAL_I2370	COG2197	response regulator
VSAL_I2374	COG1393	Belongs to the ArsC family
VSAL_I2375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VSAL_I2376	COG1876	peptidase activity
VSAL_I2379	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VSAL_I2380	COG2716	regulation of RNA biosynthetic process
VSAL_I2381	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VSAL_I2384	COG4783	chaperone-mediated protein folding
VSAL_I2385	COG1393	Belongs to the ArsC family
VSAL_I2389	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VSAL_I2390	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VSAL_I2391	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VSAL_I2392	COG0121	glutamine amidotransferase
VSAL_I2393	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VSAL_I2395	COG1960	acyl-CoA dehydrogenase activity
VSAL_I2398	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VSAL_I2399	COG0328	RNA-DNA hybrid ribonuclease activity
VSAL_I2400	COG2226	methyltransferase
VSAL_I2401	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VSAL_I2402	COG0741	lytic transglycosylase activity
VSAL_I2402	COG1388	LysM domain
VSAL_I2404	COG4372	Transposase
VSAL_I2407	COG3021	interspecies interaction between organisms
VSAL_I2411	COG0825	malonyl-CoA metabolic process
VSAL_I2412	COG0587	DNA-directed DNA polymerase activity
VSAL_I2413	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VSAL_I2414	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VSAL_I2415	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VSAL_I2416	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VSAL_I2417	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VSAL_I2418	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VSAL_I2420	COG0750	zinc metalloprotease
VSAL_I2421	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VSAL_I2422	COG0575	Belongs to the CDS family
VSAL_I2423	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VSAL_I2424	COG0233	cytoplasmic translational termination
VSAL_I2425	COG0528	UMP kinase activity
VSAL_I2426	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VSAL_I2427	COG0052	Belongs to the universal ribosomal protein uS2 family
VSAL_I2428	COG0024	Methionine aminopeptidase
VSAL_I2432	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VSAL_I2433	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VSAL_I2434	COG1862	Preprotein translocase
VSAL_I2435	COG0343	queuine tRNA-ribosyltransferase activity
VSAL_I2436	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VSAL_I2437	COG0517	IMP dehydrogenase activity
VSAL_I2439	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VSAL_I2440	COG0583	DNA-binding transcription factor activity
VSAL_I2441	COG0450	alkyl hydroperoxide reductase
VSAL_I2442	COG3142	Participates in the control of copper homeostasis
VSAL_I2443	COG3111	PFAM Bacterial OB fold (BOF) protein
VSAL_I2451	COG0704	Plays a role in the regulation of phosphate uptake
VSAL_I2452	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VSAL_I2453	COG0581	inorganic phosphate transmembrane transporter activity
VSAL_I2456	COG5002	protein histidine kinase activity
VSAL_I2457	COG0745	RESPONSE REGULATOR receiver
VSAL_I2463	COG0477	Major facilitator Superfamily
VSAL_I2465	COG1609	Transcriptional regulator
VSAL_I2467	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VSAL_I2470	COG0484	heat shock protein binding
VSAL_I2473	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VSAL_I2474	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VSAL_I2475	COG0497	DNA recombination
VSAL_I2476	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VSAL_I2477	COG2914	Belongs to the UPF0125 (RnfH) family
VSAL_I2478	COG2867	negative regulation of translational initiation
VSAL_I2479	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VSAL_I2480	COG0582	viral genome integration into host DNA
VSAL_I2486	COG4372	Transposase
VSAL_I2490	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
VSAL_I2491	COG1982	Orn Lys Arg decarboxylase major
VSAL_I2492	COG0531	amino acid
VSAL_I2493	COG1115	amino acid carrier protein
VSAL_I2494	COG3710	Transcriptional regulator
VSAL_I2496	COG2391	methyltransferase activity
VSAL_I2499	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VSAL_I2500	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VSAL_I2501	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VSAL_I2502	COG5413	integral membrane protein
VSAL_I2503	COG4135	transport system, permease component
VSAL_I2504	COG4136	ATPase activity
VSAL_I2505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VSAL_I2506	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VSAL_I2507	COG1388	LysM domain
VSAL_I2507	COG4942	peptidase
VSAL_I2508	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VSAL_I2509	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VSAL_I2510	COG0585	pseudouridine synthase activity
VSAL_I2511	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VSAL_I2512	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VSAL_I2513	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VSAL_I2514	COG0148	phosphopyruvate hydratase activity
VSAL_I2515	COG0504	CTP synthase activity
VSAL_I2516	COG3956	TIGRFAM MazG family protein
VSAL_I2518	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VSAL_I2519	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VSAL_I2521	COG0736	holo-[acyl-carrier-protein] synthase activity
VSAL_I2522	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VSAL_I2523	COG1381	Involved in DNA repair and RecF pathway recombination
VSAL_I2525	COG0571	ribonuclease III activity
VSAL_I2526	COG0681	Belongs to the peptidase S26 family
VSAL_I2527	COG0481	GTPase activity
VSAL_I2531	COG1595	DNA-templated transcription, initiation
VSAL_I2532	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VSAL_I2534	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VSAL_I2535	COG0354	folic acid binding
VSAL_I2537	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VSAL_I2538	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VSAL_I2539	COG3079	Belongs to the UPF0149 family
VSAL_I2540	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VSAL_I2541	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VSAL_I2542	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VSAL_I2544	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VSAL_I2546	COG0668	transmembrane transport
VSAL_I2547	COG3022	response to hydroperoxide
VSAL_I2548	COG1115	amino acid carrier protein
VSAL_I2551	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VSAL_I2553	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VSAL_I2554	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VSAL_I2555	COG0083	homoserine kinase activity
VSAL_I2558	COG0745	RESPONSE REGULATOR receiver
VSAL_I2560	COG0784	Response regulator, receiver
VSAL_I2560	COG2198	Histidine kinase
VSAL_I2560	COG5002	protein histidine kinase activity
VSAL_I2562	COG0069	glutamate synthase activity
VSAL_I2562	COG0067	glutamate synthase
VSAL_I2562	COG0070	glutamate synthase
VSAL_I2565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VSAL_I2567	COG2860	membrane
VSAL_I2568	COG0739	heme binding
VSAL_I2571	COG0316	Belongs to the HesB IscA family
VSAL_I2572	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VSAL_I2573	COG0628	permease
VSAL_I2574	COG2813	Specifically methylates the guanine in position
VSAL_I2575	COG0784	Response regulator, receiver
VSAL_I2575	COG2205	protein histidine kinase activity
VSAL_I2578	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VSAL_I2579	COG0444	Belongs to the ABC transporter superfamily
VSAL_I2580	COG4608	Belongs to the ABC transporter superfamily
VSAL_I2582	COG2971	BadF BadG BcrA BcrD
VSAL_I2585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VSAL_I2588	COG1840	ABC-type Fe3 transport system, periplasmic component
VSAL_I2589	COG0004	ammonium transporteR
VSAL_I2591	COG3112	Uncharacterised protein family (UPF0231)
VSAL_I2592	COG3835	regulator
VSAL_I2593	COG2610	gluconate transmembrane transporter activity
VSAL_I2594	COG1929	Belongs to the glycerate kinase type-1 family
VSAL_I2595	COG1049	propionate catabolic process, 2-methylcitrate cycle
VSAL_I2598	COG4372	Transposase
VSAL_I2602	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VSAL_I2603	COG1643	Atp-dependent helicase
VSAL_I2604	COG1489	DNA binding
VSAL_I2605	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VSAL_I2608	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VSAL_I2609	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VSAL_I2610	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VSAL_I2611	COG4372	Transposase
VSAL_I2614	COG0842	Transport permease protein
VSAL_I2615	COG1131	(ABC) transporter
VSAL_I2616	COG0288	reversible hydration of carbon dioxide
VSAL_I2623	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VSAL_I2625	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VSAL_I2626	COG2186	Transcriptional regulator
VSAL_I2628	COG0157	Belongs to the NadC ModD family
VSAL_I2630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VSAL_I2633	COG0237	dephospho-CoA kinase activity
VSAL_I2634	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VSAL_I2635	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
VSAL_I2636	COG0494	nUDIX hydrolase
VSAL_I2637	COG0653	protein targeting
VSAL_I2639	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VSAL_I2640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VSAL_I2641	COG0849	cell division
VSAL_I2642	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VSAL_I2643	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VSAL_I2644	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
VSAL_I2645	COG0772	Belongs to the SEDS family
VSAL_I2646	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VSAL_I2647	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VSAL_I2648	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VSAL_I2650	COG0768	penicillin binding
VSAL_I2651	COG3116	cell division
VSAL_I2652	COG0275	rRNA processing
VSAL_I2653	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VSAL_I2654	COG3107	peptidoglycan biosynthetic process
VSAL_I2655	COG0792	nuclease activity
VSAL_I2656	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VSAL_I2658	COG2969	positive regulation of protein catabolic process
VSAL_I2659	COG0625	glutathione transferase activity
VSAL_I2660	COG2857	Cytochrome c1
VSAL_I2661	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VSAL_I2662	COG0723	plastoquinol--plastocyanin reductase activity
VSAL_I2663	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VSAL_I2664	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VSAL_I2665	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VSAL_I2666	COG3105	Protein conserved in bacteria
VSAL_I2667	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VSAL_I2668	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VSAL_I2670	COG0187	DNA topoisomerase II activity
VSAL_I2671	COG3150	esterase
VSAL_I2673	COG3151	Protein conserved in bacteria
VSAL_I2674	COG0494	nUDIX hydrolase
VSAL_I2675	COG1538	Outer membrane efflux protein
VSAL_I2676	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VSAL_I2676	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
VSAL_I2677	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VSAL_I2679	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VSAL_I2680	COG3025	triphosphatase activity
VSAL_I2681	COG1392	Phosphate transport regulator
VSAL_I2682	COG0306	phosphate transporter
VSAL_I2683	COG4991	sh3 domain protein
VSAL_I2684	COG4372	Transposase
VSAL_I2688	COG3267	Type II secretory pathway component ExeA
VSAL_I2688	COG3409	Peptidoglycan-binding domain 1 protein
VSAL_I2689	COG0617	tRNA 3'-terminal CCA addition
VSAL_I2690	COG1968	undecaprenyl-diphosphatase activity
VSAL_I2692	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VSAL_I2693	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VSAL_I2694	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VSAL_I2695	COG1610	YqeY-like protein
VSAL_I2696	COG0358	DNA primase activity
VSAL_I2697	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VSAL_I2699	COG0318	PFAM AMP-dependent synthetase and ligase
VSAL_I2701	COG0469	pyruvate kinase activity
VSAL_I2704	COG3706	GGDEF domain
VSAL_I2706	COG0028	Belongs to the TPP enzyme family
VSAL_I2707	COG4372	Transposase
VSAL_I2710	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VSAL_I2710	COG0165	Argininosuccinate lyase
VSAL_I2712	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VSAL_I2713	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VSAL_I2713	COG0678	peroxiredoxin activity
VSAL_I2715	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VSAL_I2722	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VSAL_I2723	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VSAL_I2725	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VSAL_I2726	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VSAL_I2727	COG0546	phosphoglycolate phosphatase activity
VSAL_I2728	COG0180	Tryptophanyl-tRNA synthetase
VSAL_I2729	COG0512	Glutamine amidotransferase of anthranilate synthase
VSAL_I2732	COG4372	Transposase
VSAL_I2733	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VSAL_I2735	COG1012	belongs to the aldehyde dehydrogenase family
VSAL_I2737	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VSAL_I2738	COG1765	OsmC-like protein
VSAL_I2739	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VSAL_I2742	COG1609	Transcriptional regulator
VSAL_I2743	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VSAL_I2744	COG0254	rRNA binding
VSAL_I2745	COG0281	malic enzyme
VSAL_I2747	COG0626	cystathionine gamma-synthase activity
VSAL_I2748	COG0527	aspartate kinase activity
VSAL_I2748	COG0460	homoserine dehydrogenase
VSAL_I2749	COG0583	DNA-binding transcription factor activity
VSAL_I2750	COG1022	Amp-dependent synthetase and ligase
VSAL_I2753	COG4372	Transposase
VSAL_I2754	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VSAL_I2755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VSAL_I2756	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VSAL_I2757	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VSAL_I2758	COG0137	argininosuccinate synthase activity
VSAL_I2759	COG4372	Transposase
VSAL_I2762	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VSAL_I2763	COG0359	binds to the 23S rRNA
VSAL_I2764	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VSAL_I2765	COG2965	DNA replication, synthesis of RNA primer
VSAL_I2766	COG0360	Binds together with S18 to 16S ribosomal RNA
VSAL_I2767	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VSAL_I2768	COG0557	exoribonuclease II activity
VSAL_I2769	COG1959	2 iron, 2 sulfur cluster binding
VSAL_I2770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VSAL_I2770	COG1017	nitric oxide dioxygenase activity
VSAL_I2771	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VSAL_I2772	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VSAL_I2774	COG0330	HflC and HflK could
VSAL_I2775	COG0330	HflC and HflK could
VSAL_I2776	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VSAL_I2777	COG1923	regulation of RNA biosynthetic process
VSAL_I2778	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VSAL_I2779	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VSAL_I2781	COG0802	atpase or kinase
VSAL_I2782	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VSAL_I2783	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VSAL_I2784	COG1162	GTPase activity
VSAL_I2785	COG0688	phosphatidylethanolamine metabolic process
VSAL_I2787	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VSAL_I2788	COG1053	succinate dehydrogenase
VSAL_I2789	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VSAL_I2790	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VSAL_I2791	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VSAL_I2792	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VSAL_I2793	COG1509	lysine 2,3-aminomutase activity
VSAL_I2794	COG0205	6-phosphofructokinase activity
VSAL_I2797	COG0745	RESPONSE REGULATOR receiver
VSAL_I2798	COG2205	protein histidine kinase activity
VSAL_I2799	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VSAL_I2800	COG1045	serine acetyltransferase
VSAL_I2801	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VSAL_I2802	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VSAL_I2803	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VSAL_I2804	COG4942	peptidase
VSAL_I2806	COG1027	Aspartate ammonia-lyase
VSAL_I2811	COG4232	protein-disulfide reductase activity
VSAL_I2812	COG0363	glucosamine-6-phosphate deaminase activity
VSAL_I2813	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSAL_I2813	COG2213	PTS system mannitol-specific
VSAL_I2814	COG0246	Mannitol dehydrogenase
VSAL_I2815	COG3722	fumarate hydratase activity
VSAL_I2818	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VSAL_I2819	COG0640	Transcriptional regulator
VSAL_I2821	COG1252	NADH dehydrogenase
VSAL_I2822	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VSAL_I2823	COG1349	DNA-binding transcription factor activity
VSAL_I2825	COG2095	MarC family integral membrane protein
VSAL_I2826	COG3385	transposase activity
VSAL_I2828	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VSAL_I2829	COG0784	Response regulator, receiver
VSAL_I2829	COG2205	protein histidine kinase activity
VSAL_I2829	COG2198	Histidine kinase
VSAL_I2830	COG2814	Major facilitator Superfamily
VSAL_I2833	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VSAL_I2834	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VSAL_I2835	COG0511	ligase activity, forming carbon-carbon bonds
VSAL_I2836	COG0439	Biotin carboxylase
VSAL_I2837	COG2264	protein methyltransferase activity
VSAL_I2838	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VSAL_I2839	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VSAL_I2841	COG0789	Transcriptional regulator
VSAL_I2842	COG0138	bifunctional purine biosynthesis protein purh
VSAL_I2843	COG0151	Belongs to the GarS family
VSAL_I2844	COG3385	transposase activity
VSAL_I2847	COG1253	flavin adenine dinucleotide binding
VSAL_I2848	COG3068	Protein conserved in bacteria
VSAL_I2849	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VSAL_I2851	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VSAL_I2858	COG2197	response regulator
VSAL_I2865	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VSAL_I2866	COG0085	RNA polymerase activity
VSAL_I2867	COG0222	ribosome binding
VSAL_I2868	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VSAL_I2869	COG0081	regulation of translation
VSAL_I2870	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VSAL_I2871	COG0250	Participates in transcription elongation, termination and antitermination
VSAL_I2872	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VSAL_I2875	COG1072	(Pantothenic acid kinase))
VSAL_I2877	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VSAL_I2879	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VSAL_I2882	COG4372	Transposase
VSAL_I2884	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VSAL_I2887	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VSAL_I2889	COG1309	transcriptional regulator
VSAL_I2890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VSAL_I2891	COG0534	Mate efflux family protein
VSAL_I2893	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VSAL_I2894	COG2937	Belongs to the GPAT DAPAT family
VSAL_I2895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VSAL_I2896	COG3161	chorismate lyase activity
VSAL_I2898	COG0705	Rhomboid family
VSAL_I2899	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VSAL_I2901	COG2177	Part of the ABC transporter FtsEX involved in
VSAL_I2902	COG2884	Cell division ATP-binding protein ftsE
VSAL_I2903	COG0552	protein localization to endoplasmic reticulum
VSAL_I2904	COG0742	ribosomal rna small subunit methyltransferase
VSAL_I2910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VSAL_I2911	COG0316	Belongs to the HesB IscA family
VSAL_I2911	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
VSAL_I2912	COG1218	3'(2'),5'-bisphosphate nucleotidase
VSAL_I2913	COG0494	nUDIX hydrolase
VSAL_I2915	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VSAL_I2916	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VSAL_I2917	COG3156	type II secretion system protein K
VSAL_I2918	COG4795	General secretion pathway protein
VSAL_I2919	COG2165	general secretion pathway protein
VSAL_I2920	COG2165	general secretion pathway protein
VSAL_I2921	COG2165	general secretion pathway protein
VSAL_I2922	COG1459	type II secretion system
VSAL_I2923	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VSAL_I2925	COG3031	protein transport across the cell outer membrane
VSAL_I2926	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VSAL_I2927	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VSAL_I2928	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VSAL_I2930	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VSAL_I2931	COG2267	carboxylic ester hydrolase activity
VSAL_I2932	COG0561	phosphatase activity
VSAL_I2936	COG0456	acetyltransferase
VSAL_I2937	COG1490	D-aminoacyl-tRNA deacylase activity
VSAL_I2938	COG1295	ribonuclease BN
VSAL_I2940	COG0174	glutamine synthetase
VSAL_I2943	COG4372	Transposase
VSAL_I2944	COG1522	sequence-specific DNA binding
VSAL_I2945	COG0742	ribosomal rna small subunit methyltransferase
VSAL_I2946	COG0589	response to stress
VSAL_I2947	COG1528	Iron-storage protein
VSAL_I2949	COG2081	HI0933 family
VSAL_I2953	COG4372	Transposase
VSAL_I2956	COG0800	Aldolase
VSAL_I2961	COG0071	Belongs to the small heat shock protein (HSP20) family
VSAL_I2962	COG3385	transposase activity
VSAL_I2963	COG3977	Valine--pyruvate aminotransferase
VSAL_I2964	COG0752	glycyl-tRNA synthetase alpha subunit
VSAL_I2965	COG0751	glycine-tRNA ligase activity
VSAL_I2966	COG0366	Alpha amylase catalytic
VSAL_I2968	COG0425	Belongs to the sulfur carrier protein TusA family
VSAL_I2971	COG0583	DNA-binding transcription factor activity
VSAL_I2972	COG0604	alcohol dehydrogenase
VSAL_I2973	COG0183	Belongs to the thiolase family
VSAL_I2974	COG1024	Enoyl-CoA hydratase
VSAL_I2974	COG1250	3-hydroxyacyl-CoA dehydrogenase
VSAL_I2975	COG1739	Uncharacterized protein family UPF0029
VSAL_I2976	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VSAL_I2977	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
VSAL_I2979	COG0612	Peptidase, M16
VSAL_I2981	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VSAL_I2983	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VSAL_I2984	COG0352	thiamine-phosphate diphosphorylase activity
VSAL_I2985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VSAL_I2986	COG2104	thiamine diphosphate biosynthetic process
VSAL_I2987	COG2022	thiamine diphosphate biosynthetic process
VSAL_I2988	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VSAL_I2990	COG0006	proline dipeptidase activity
VSAL_I2990	COG0006	proline dipeptidase activity
VSAL_I2995	COG1322	Protein conserved in bacteria
VSAL_I2998	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VSAL_I2999	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VSAL_I3001	COG0805	protein transport
VSAL_I3003	COG0084	hydrolase, TatD family'
VSAL_I3009	COG5433	transposase activity
VSAL_I3011	COG2089	acid synthase
VSAL_I3014	COG2244	polysaccharide biosynthetic process
VSAL_I3024	COG1216	Glycosyl transferase, family 2
VSAL_I3027	COG0463	Glycosyl transferase, family 2
VSAL_I3030	COG4641	Protein conserved in bacteria
VSAL_I3030	COG0438	transferase activity, transferring glycosyl groups
VSAL_I3032	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VSAL_I3047	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VSAL_I3049	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VSAL_I3050	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VSAL_I3057	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VSAL_I3058	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VSAL_I3059	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VSAL_I3060	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VSAL_I3061	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VSAL_I3062	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VSAL_I3063	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VSAL_I3065	COG0356	it plays a direct role in the translocation of protons across the membrane
VSAL_I3066	COG3312	ion transport
VSAL_I3067	COG1475	DNA binding
VSAL_I3068	COG1192	Involved in chromosome partitioning
VSAL_I3069	COG0357	Ribosomal RNA small subunit methyltransferase G
VSAL_I3070	COG0445	tRNA wobble uridine modification
VSAL_II0002	COG0251	oxidation-reduction process
VSAL_II0011	COG0514	ATP-dependent DNA helicase (RecQ)
VSAL_II0021	COG0259	pyridoxamine-phosphate oxidase activity
VSAL_II0023	COG4372	Transposase
VSAL_II0026	COG4067	protein conserved in archaea
VSAL_II0026	COG0189	ligase activity
VSAL_II0027	COG0861	Integral membrane protein TerC family
VSAL_II0031	COG4372	Transposase
VSAL_II0038	COG0058	SHG alpha-glucan phosphorylase activity
VSAL_II0039	COG1640	4-alpha-glucanotransferase
VSAL_II0046	COG4372	Transposase
VSAL_II0052	COG2203	Gaf domain
VSAL_II0052	COG3706	GGDEF domain
VSAL_II0052	COG4251	negative regulation of phosphorylation
VSAL_II0052	COG5001	Diguanylate cyclase
VSAL_II0053	COG2205	protein histidine kinase activity
VSAL_II0053	COG5002	protein histidine kinase activity
VSAL_II0053	COG0784	Response regulator, receiver
VSAL_II0057	COG0745	RESPONSE REGULATOR receiver
VSAL_II0060	COG1132	(ABC) transporter
VSAL_II0064	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VSAL_II0069	COG4372	Transposase
VSAL_II0073	COG3724	N-succinylarginine dihydrolase activity
VSAL_II0077	COG2207	Transcriptional regulator
VSAL_II0077	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VSAL_II0078	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VSAL_II0079	COG2866	Carboxypeptidase
VSAL_II0080	COG4372	Transposase
VSAL_II0089	COG1609	Transcriptional regulator
VSAL_II0090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSAL_II0090	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSAL_II0091	COG1105	Belongs to the carbohydrate kinase PfkB family
VSAL_II0092	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSAL_II0092	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSAL_II0092	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VSAL_II0098	COG4372	Transposase
VSAL_II0101	COG2195	Cleaves the N-terminal amino acid of tripeptides
VSAL_II0102	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VSAL_II0102	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VSAL_II0103	COG1349	DNA-binding transcription factor activity
VSAL_II0104	COG2084	Dehydrogenase
VSAL_II0112	COG0811	peptide transport
VSAL_II0113	COG0811	peptide transport
VSAL_II0114	COG0848	biopolymer transport protein
VSAL_II0124	COG1121	(ABC) transporter
VSAL_II0134	COG3397	chitin binding
VSAL_II0136	COG1451	nucleotide metabolic process
VSAL_II0141	COG0217	transcriptional regulatory protein
VSAL_II0142	COG0513	Belongs to the DEAD box helicase family
VSAL_II0143	COG3706	GGDEF domain
VSAL_II0143	COG0745	RESPONSE REGULATOR receiver
VSAL_II0144	COG0745	RESPONSE REGULATOR receiver
VSAL_II0144	COG3706	GGDEF domain
VSAL_II0145	COG2814	Major facilitator Superfamily
VSAL_II0146	COG0513	Belongs to the DEAD box helicase family
VSAL_II0147	COG3706	GGDEF domain
VSAL_II0150	COG1120	ATPase activity
VSAL_II0151	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VSAL_II0152	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VSAL_II0155	COG0604	alcohol dehydrogenase
VSAL_II0159	COG0109	protoheme IX farnesyltransferase activity
VSAL_II0160	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
VSAL_II0161	COG1845	cytochrome c oxidase, subunit III
VSAL_II0163	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
VSAL_II0170	COG0840	transmembrane signaling receptor activity
VSAL_II0175	COG4372	Transposase
VSAL_II0178	COG0583	DNA-binding transcription factor activity
VSAL_II0179	COG1162	GTPase activity
VSAL_II0180	COG2239	Acts as a magnesium transporter
VSAL_II0182	COG0589	response to stress
VSAL_II0183	COG0659	secondary active sulfate transmembrane transporter activity
VSAL_II0194	COG2205	protein histidine kinase activity
VSAL_II0198	COG5002	protein histidine kinase activity
VSAL_II0200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VSAL_II0210	COG0235	Class ii aldolase
VSAL_II0211	COG3622	Belongs to the hyi family
VSAL_II0212	COG2610	gluconate transmembrane transporter activity
VSAL_II0213	COG3791	Glutathione-dependent formaldehyde-activating
VSAL_II0214	COG4667	esterase of the alpha-beta hydrolase superfamily
VSAL_II0215	COG0753	catalase activity
VSAL_II0218	COG0488	(ABC) transporter
VSAL_II0219	COG4372	Transposase
VSAL_II0222	COG2176	DNA-directed DNA polymerase activity
VSAL_II0225	COG0789	Transcriptional regulator
VSAL_II0229	COG4372	Transposase
VSAL_II0230	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VSAL_II0231	COG0784	Response regulator, receiver
VSAL_II0231	COG0835	chemotaxis
VSAL_II0236	COG4372	Transposase
VSAL_II0237	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VSAL_II0239	COG0297	glycogen (starch) synthase activity
VSAL_II0243	COG4372	Transposase
VSAL_II0245	COG2146	nitrite reductase [NAD(P)H] activity
VSAL_II0245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VSAL_II0247	COG2223	nitrite transmembrane transporter activity
VSAL_II0248	COG0515	serine threonine protein kinase
VSAL_II0248	COG2815	serine threonine protein kinase
VSAL_II0263	COG1028	Short-chain dehydrogenase reductase Sdr
VSAL_II0266	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VSAL_II0270	COG4372	Transposase
VSAL_II0280	COG0330	HflC and HflK could
VSAL_II0283	COG3385	transposase activity
VSAL_II0284	COG2084	Dehydrogenase
VSAL_II0286	COG4181	ATPase activity
VSAL_II0287	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VSAL_II0290	COG1028	Short-chain dehydrogenase reductase Sdr
VSAL_II0291	COG0583	DNA-binding transcription factor activity
VSAL_II0294	COG3300	MHYT domain
VSAL_II0294	COG5001	Diguanylate cyclase
VSAL_II0295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VSAL_II0296	COG1215	transferase activity, transferring glycosyl groups
VSAL_II0303	COG0438	transferase activity, transferring glycosyl groups
VSAL_II0305	COG0438	transferase activity, transferring glycosyl groups
VSAL_II0306	COG2204	response regulator
VSAL_II0308	COG0745	RESPONSE REGULATOR receiver
VSAL_II0311	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
VSAL_II0311	COG2885	chlorophyll binding
VSAL_II0319	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VSAL_II0320	COG3300	MHYT domain
VSAL_II0320	COG5001	Diguanylate cyclase
VSAL_II0321	COG1215	transferase activity, transferring glycosyl groups
VSAL_II0327	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
VSAL_II0328	COG1366	Belongs to the anti-sigma-factor antagonist family
VSAL_II0335	COG4372	Transposase
VSAL_II0337	COG0584	glycerophosphoryl diester phosphodiesterase
VSAL_II0339	COG0561	phosphatase activity
VSAL_II0341	COG2855	membrane
VSAL_II0352	COG2194	sulfuric ester hydrolase activity
VSAL_II0354	COG0745	RESPONSE REGULATOR receiver
VSAL_II0355	COG0642	Histidine kinase
VSAL_II0357	COG3119	arylsulfatase activity
VSAL_II0360	COG0583	DNA-binding transcription factor activity
VSAL_II0361	COG4134	Bacterial extracellular solute-binding protein
VSAL_II0363	COG2201	protein-glutamate methylesterase activity
VSAL_II0369	COG4964	Belongs to the GSP D family
VSAL_II0381	COG5002	protein histidine kinase activity
VSAL_II0381	COG2198	Histidine kinase
VSAL_II0381	COG0784	Response regulator, receiver
VSAL_II0383	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VSAL_II0384	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VSAL_II0385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VSAL_II0386	COG1349	DNA-binding transcription factor activity
VSAL_II0387	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VSAL_II0389	COG4372	Transposase
VSAL_II0393	COG0784	Response regulator, receiver
VSAL_II0393	COG2205	protein histidine kinase activity
VSAL_II0394	COG1858	cytochrome C peroxidase
VSAL_II0395	COG0247	lactate metabolic process
VSAL_II0396	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
VSAL_II0397	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VSAL_II0398	COG3383	formate dehydrogenase (NAD+) activity
VSAL_II0399	COG2195	Cleaves the N-terminal amino acid of tripeptides
VSAL_II0401	COG2207	Transcriptional regulator
VSAL_II0402	COG2315	Protein conserved in bacteria
VSAL_II0416	COG0633	Ferredoxin
VSAL_II0416	COG3217	Mosc domain protein beta barrel domain protein
VSAL_II0417	COG5002	protein histidine kinase activity
VSAL_II0421	COG2354	Protein conserved in bacteria
VSAL_II0426	COG2199	diguanylate cyclase activity
VSAL_II0426	COG2203	Gaf domain
VSAL_II0427	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VSAL_II0428	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VSAL_II0429	COG0513	Belongs to the DEAD box helicase family
VSAL_II0433	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VSAL_II0434	COG1566	PFAM secretion protein HlyD family protein
VSAL_II0436	COG3706	GGDEF domain
VSAL_II0439	COG0513	Belongs to the DEAD box helicase family
VSAL_II0440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VSAL_II0444	COG0765	amino acid transport
VSAL_II0447	COG1126	abc transporter atp-binding protein
VSAL_II0448	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VSAL_II0449	COG3593	DNA synthesis involved in DNA repair
VSAL_II0450	COG0737	Belongs to the 5'-nucleotidase family
VSAL_II0452	COG3706	GGDEF domain
VSAL_II0455	COG2390	Transcriptional regulator
VSAL_II0457	COG0813	purine-nucleoside phosphorylase activity
VSAL_II0458	COG0569	domain protein
VSAL_II0459	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VSAL_II0460	COG0668	transmembrane transport
VSAL_II0464	COG3530	Putative quorum-sensing-regulated virulence factor
VSAL_II0467	COG4989	oxidoreductase activity
VSAL_II0468	COG0418	dihydroorotase activity
VSAL_II0469	COG3036	rescue of stalled ribosome
VSAL_II0470	COG4372	Transposase
VSAL_II0475	COG4172	Belongs to the ABC transporter superfamily
VSAL_II0477	COG4171	peptide transport system, permease
VSAL_II0478	COG4168	peptide transport system, permease
VSAL_II0480	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VSAL_II0481	COG1842	Phage shock protein A
VSAL_II0484	COG3106	COG3106 Predicted ATPase
VSAL_II0486	COG0351	phosphomethylpyrimidine kinase
VSAL_II0487	COG1116	anion transmembrane transporter activity
VSAL_II0488	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VSAL_II0489	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VSAL_II0490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
VSAL_II0491	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
VSAL_II0496	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VSAL_II0498	COG0835	chemotaxis
VSAL_II0498	COG0784	Response regulator, receiver
VSAL_II0499	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VSAL_II0500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VSAL_II0501	COG0516	GMP reductase activity
VSAL_II0513	COG3706	GGDEF domain
VSAL_II0515	COG4372	Transposase
VSAL_II0518	COG1560	Kdo2-lipid A biosynthetic process
VSAL_II0520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VSAL_II0521	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VSAL_II0523	COG2304	oxidoreductase activity
VSAL_II0527	COG0714	Associated with various cellular activities
VSAL_II0531	COG2050	protein possibly involved in aromatic compounds catabolism
VSAL_II0546	COG2184	nucleotidyltransferase activity
VSAL_II0547	COG3041	Addiction module toxin RelE StbE family
VSAL_II0554	COG2161	toxin-antitoxin pair type II binding
VSAL_II0555	COG4115	mRNA cleavage
VSAL_II0565	COG0513	Belongs to the DEAD box helicase family
VSAL_II0567	COG0772	Belongs to the SEDS family
VSAL_II0569	COG0564	pseudouridine synthase activity
VSAL_II0570	COG0564	pseudouridine synthase activity
VSAL_II0572	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VSAL_II0574	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VSAL_II0576	COG1609	Transcriptional regulator
VSAL_II0577	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSAL_II0577	COG1263	PTS System
VSAL_II0578	COG0366	Alpha amylase catalytic
VSAL_II0580	COG0602	queuosine metabolic process
VSAL_II0581	COG1940	carbohydrate kinase activity
VSAL_II0582	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VSAL_II0591	COG3437	response regulator, receiver
VSAL_II0591	COG0784	Response regulator, receiver
VSAL_II0603	COG2926	Belongs to the UPF0265 family
VSAL_II0605	COG3132	Protein of unknown function, DUF480
VSAL_II0607	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VSAL_II0608	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VSAL_II0614	COG1278	Cold shock
VSAL_II0618	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VSAL_II0623	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VSAL_II0624	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VSAL_II0636	COG0023	Translation Initiation Factor
VSAL_II0641	COG0045	succinate-CoA ligase (ADP-forming) activity
VSAL_II0641	COG1042	CoA-binding domain protein
VSAL_II0641	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VSAL_II0646	COG0521	Mo-molybdopterin cofactor biosynthetic process
VSAL_II0648	COG3140	Belongs to the UPF0181 family
VSAL_II0650	COG0745	RESPONSE REGULATOR receiver
VSAL_II0653	COG4533	DNA binding
VSAL_II0656	COG3123	guanosine phosphorylase activity
VSAL_II0657	COG0513	Belongs to the DEAD box helicase family
VSAL_II0664	COG0800	Aldolase
VSAL_II0665	COG2610	gluconate transmembrane transporter activity
VSAL_II0666	COG3265	gluconokinase activity
VSAL_II0667	COG0129	dihydroxy-acid dehydratase activity
VSAL_II0668	COG1609	Transcriptional regulator
VSAL_II0670	COG0523	cobalamin synthesis protein
VSAL_II0671	COG1132	(ABC) transporter
VSAL_II0673	COG0786	glutamate:sodium symporter activity
VSAL_II0674	COG0786	glutamate:sodium symporter activity
VSAL_II0677	COG1216	Glycosyl transferase, family 2
VSAL_II0677	COG0463	Glycosyl transferase, family 2
VSAL_II0684	COG0586	Pfam SNARE associated Golgi protein
VSAL_II0685	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VSAL_II0686	COG0363	glucosamine-6-phosphate deaminase activity
VSAL_II0687	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VSAL_II0692	COG4591	ABC-type transport system involved in lipoprotein release permease component
VSAL_II0693	COG1136	(ABC) transporter
VSAL_II0694	COG4591	ABC-type transport system involved in lipoprotein release permease component
VSAL_II0696	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VSAL_II0702	COG0545	Peptidyl-prolyl cis-trans isomerase
VSAL_II0705	COG1228	amidohydrolase
VSAL_II0706	COG0010	Belongs to the arginase family
VSAL_II0707	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VSAL_II0708	COG2986	histidine ammonia-lyase
VSAL_II0714	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VSAL_II0721	COG2190	(PTS) system
VSAL_II0721	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSAL_II0721	COG1263	PTS System
VSAL_II0723	COG0745	RESPONSE REGULATOR receiver
VSAL_II0725	COG0484	heat shock protein binding
VSAL_II0727	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VSAL_II0728	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VSAL_II0729	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VSAL_II0730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VSAL_II0731	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VSAL_II0732	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VSAL_II0734	COG1663	tetraacyldisaccharide 4'-kinase activity
VSAL_II0735	COG1132	(ABC) transporter
VSAL_II0736	COG2333	competence protein COMEC
VSAL_II0736	COG0658	competence protein
VSAL_II0738	COG1227	inorganic diphosphatase activity
VSAL_II0751	COG4372	Transposase
VSAL_II0753	COG2885	chlorophyll binding
VSAL_II0758	COG4232	protein-disulfide reductase activity
VSAL_II0759	COG3118	belongs to the thioredoxin family
VSAL_II0764	COG0509	glycine decarboxylation via glycine cleavage system
VSAL_II0765	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VSAL_II0765	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VSAL_II0771	COG0840	transmembrane signaling receptor activity
VSAL_II0772	COG0243	molybdopterin cofactor binding
VSAL_II0773	COG3005	denitrification pathway
VSAL_II0774	COG4459	periplasmic nitrate reductase
VSAL_II0776	COG3122	Protein conserved in bacteria
VSAL_II0779	COG1011	Hydrolase
VSAL_II0780	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VSAL_II0781	COG4149	molybdate abc transporter
VSAL_II0782	COG0725	ABC transporter, periplasmic molybdate-binding protein
VSAL_II0783	COG1492	cobalamin metabolic process
VSAL_II0786	COG0741	lytic transglycosylase activity
VSAL_II0787	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VSAL_II0788	COG4067	protein conserved in archaea
VSAL_II0788	COG0189	ligase activity
VSAL_II0790	COG0602	queuosine metabolic process
VSAL_II0791	COG1328	CTP reductase activity
VSAL_II0794	COG0519	Catalyzes the synthesis of GMP from XMP
VSAL_II0796	COG1999	signal sequence binding
VSAL_II0798	COG0697	spore germination
VSAL_II0810	COG3842	ATPase activity
VSAL_II0811	COG1840	ABC-type Fe3 transport system, periplasmic component
VSAL_II0814	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VSAL_II0817	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VSAL_II0820	COG2207	Transcriptional regulator
VSAL_II0820	COG1917	Cupin 2, conserved barrel domain protein
VSAL_II0821	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VSAL_II0824	COG3037	sugar-specific permease SgaT UlaA
VSAL_II0825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSAL_II0826	COG0390	transport system, permease component
VSAL_II0833	COG4372	Transposase
VSAL_II0837	COG1063	alcohol dehydrogenase
VSAL_II0840	COG1067	ATP-dependent peptidase activity
VSAL_II0842	COG0673	inositol 2-dehydrogenase activity
VSAL_II0847	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VSAL_II0848	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VSAL_II0851	COG0745	RESPONSE REGULATOR receiver
VSAL_II0857	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VSAL_II0858	COG2226	methyltransferase
VSAL_II0859	COG0156	8-amino-7-oxononanoate synthase activity
VSAL_II0860	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VSAL_II0863	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VSAL_II0865	COG3272	Protein of unknown function (DUF1722)
VSAL_II0866	COG0415	Belongs to the DNA photolyase family
VSAL_II0876	COG4372	Transposase
VSAL_II0879	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VSAL_II0881	COG2814	Major facilitator Superfamily
VSAL_II0882	COG0583	DNA-binding transcription factor activity
VSAL_II0884	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VSAL_II0885	COG3706	GGDEF domain
VSAL_II0887	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VSAL_II0889	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
VSAL_II0893	COG2207	Transcriptional regulator
VSAL_II0894	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSAL_II0894	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSAL_II0894	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSAL_II0897	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSAL_II0897	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSAL_II0897	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSAL_II0902	COG0848	biopolymer transport protein
VSAL_II0903	COG0811	peptide transport
VSAL_II0904	COG0811	peptide transport
VSAL_II0908	COG1120	ATPase activity
VSAL_II0910	COG4977	sequence-specific DNA binding
VSAL_II0911	COG0488	(ABC) transporter
VSAL_II0913	COG1902	pentaerythritol trinitrate reductase activity
VSAL_II0914	COG2814	Major facilitator Superfamily
VSAL_II0915	COG0583	DNA-binding transcription factor activity
VSAL_II0921	COG3706	GGDEF domain
VSAL_II0922	COG2201	protein-glutamate methylesterase activity
VSAL_II0923	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VSAL_II0928	COG4372	Transposase
VSAL_II0932	COG1215	transferase activity, transferring glycosyl groups
VSAL_II0937	COG2194	sulfuric ester hydrolase activity
VSAL_II0938	COG2731	YhcH YjgK YiaL family protein
VSAL_II0944	COG2137	regulation of response to DNA damage stimulus
VSAL_II0946	COG0697	spore germination
VSAL_II0948	COG1131	(ABC) transporter
VSAL_II0950	COG5001	Diguanylate cyclase
VSAL_II0951	COG3706	GGDEF domain
VSAL_II0952	COG3706	GGDEF domain
VSAL_II0952	COG0745	RESPONSE REGULATOR receiver
VSAL_II0953	COG1253	flavin adenine dinucleotide binding
VSAL_II0954	COG0110	maltose O-acetyltransferase activity
VSAL_II0963	COG1073	alpha beta
VSAL_II0973	COG4372	Transposase
VSAL_II0980	COG4221	oxidoreductase activity
VSAL_II0991	COG4372	Transposase
VSAL_II0995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSAL_II0997	COG3706	GGDEF domain
VSAL_II0998	COG0123	including yeast histone deacetylase and acetoin utilization protein
VSAL_II1002	COG1115	amino acid carrier protein
VSAL_II1003	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VSAL_II1007	COG4372	Transposase
VSAL_II1012	COG2205	protein histidine kinase activity
VSAL_II1012	COG0784	Response regulator, receiver
VSAL_II1018	COG4372	Transposase
VSAL_II1020	COG0628	permease
VSAL_II1024	COG1486	melibiose metabolic process
VSAL_II1025	COG0583	DNA-binding transcription factor activity
VSAL_II1031	COG3842	ATPase activity
VSAL_II1032	COG2217	Heavy metal translocating P-type atpase
VSAL_II1034	COG1278	Cold shock
VSAL_II1036	COG0668	transmembrane transport
VSAL_II1050	COG4372	Transposase
VSAL_II1056	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VSAL_II1057	COG0446	pyridine nucleotide-disulphide oxidoreductase
VSAL_II1057	COG1902	pentaerythritol trinitrate reductase activity
VSAL_II1061	COG3706	GGDEF domain
VSAL_II1066	COG1982	Orn Lys Arg decarboxylase major
VSAL_II1067	COG0531	amino acid
VSAL_II1075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VSAL_II1077	COG1760	l-serine dehydratase
VSAL_II1080	COG2119	membrane
VSAL_II1084	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VSAL_II1090	COG4372	Transposase
VSAL_II1093	COG4067	protein conserved in archaea
VSAL_II1093	COG0189	ligase activity
VSAL_II1094	COG0861	Integral membrane protein TerC family
VSAL_II1098	COG2274	protein secretion by the type I secretion system
VSAL_II1102	COG1444	tRNA N-acetyltransferase activity
VSAL_p320_31	COG2801	Transposase and inactivated derivatives
VSAL_p54_03	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
VSAL_p54_03	COG2755	lipolytic protein G-D-S-L family
VSAL_p840_23	COG0741	lytic transglycosylase activity
VSAL_p840_33	COG2003	Belongs to the UPF0758 family
VSAL_p840_36	COG3501	Rhs element vgr protein
VSAL_p840_39	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VSAL_p840_64	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
VSAL_p840_70	COG1028	Short-chain dehydrogenase reductase Sdr