locus-tag	class	description
ABC0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABC0002	COG0592	DNA-directed DNA polymerase activity
ABC0003	COG2501	S4 domain
ABC0004	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ABC0006	COG0187	DNA topoisomerase II activity
ABC0007	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ABC0008	COG1028	Short-chain dehydrogenase reductase Sdr
ABC0011	COG0516	GMP reductase activity
ABC0011	COG0517	IMP dehydrogenase activity
ABC0013	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABC0014	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABC0015	COG2508	Transcriptional regulator
ABC0016	COG3829	transcription factor binding
ABC0017	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC0018	COG1757	Na H antiporter
ABC0020	COG0006	proline dipeptidase activity
ABC0024	COG1012	belongs to the aldehyde dehydrogenase family
ABC0026	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC0027	COG0765	amino acid transport
ABC0029	COG4608	Belongs to the ABC transporter superfamily
ABC0030	COG0444	Belongs to the ABC transporter superfamily
ABC0031	COG0601	transmembrane transport
ABC0032	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC0034	COG0590	tRNA wobble adenosine to inosine editing
ABC0035	COG0740	serine-type endopeptidase activity
ABC0037	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ABC0038	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ABC0039	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ABC0044	COG4191	Histidine kinase
ABC0045	COG2204	response regulator
ABC0047	COG1012	belongs to the aldehyde dehydrogenase family
ABC0049	COG1982	Orn Lys Arg decarboxylase major
ABC0050	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABC0051	COG3870	Protein conserved in bacteria
ABC0052	COG0470	DNA polymerase III
ABC0053	COG1774	PSP1 C-terminal conserved region
ABC0054	COG4467	Involved in initiation control of chromosome replication
ABC0055	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ABC0056	COG2827	Endonuclease containing a URI domain
ABC0057	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ABC0058	COG2002	toxin-antitoxin pair type II binding
ABC0061	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC0061	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC0064	COG0488	(ABC) transporter
ABC0067	COG0084	hydrolase, TatD family'
ABC0068	COG3583	domain protein
ABC0068	COG3584	3D domain protein
ABC0069	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ABC0070	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABC0072	COG4466	Protein conserved in bacteria
ABC0074	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ABC0075	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABC0076	COG0251	oxidation-reduction process
ABC0077	COG2088	sporulation resulting in formation of a cellular spore
ABC0078	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABC0079	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABC0080	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ABC0081	COG0193	aminoacyl-tRNA hydrolase activity
ABC0083	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABC0084	COG2002	toxin-antitoxin pair type II binding
ABC0086	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ABC0088	COG2244	polysaccharide biosynthetic process
ABC0089	COG3956	TIGRFAM MazG family protein
ABC0090	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ABC0091	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABC0092	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABC0093	COG1247	-acetyltransferase
ABC0094	COG0492	ferredoxin-NADP+ reductase activity
ABC0099	COG1098	S1 RNA binding domain
ABC0100	COG2851	Citrate transporter
ABC0101	COG2208	phosphoserine phosphatase activity
ABC0102	COG2304	oxidoreductase activity
ABC0103	COG0515	serine threonine protein kinase
ABC0104	COG0037	tRNA processing
ABC0105	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ABC0106	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABC0107	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ABC0108	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ABC0109	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABC0110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ABC0111	COG0512	Glutamine amidotransferase of anthranilate synthase
ABC0112	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ABC0113	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ABC0114	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ABC0115	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ABC0116	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABC0117	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ABC0119	COG3880	PFAM UvrB UvrC protein
ABC0120	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ABC0121	COG0542	response to heat
ABC0122	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ABC0123	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ABC0124	COG4956	integral membrane protein (PIN domain superfamily)
ABC0125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ABC0126	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ABC0127	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABC0128	COG1045	serine acetyltransferase
ABC0129	COG0215	cysteine-tRNA ligase activity
ABC0131	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABC0132	COG3688	RNA-binding protein containing a PIN domain
ABC0135	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABC0136	COG0250	Participates in transcription elongation, termination and antitermination
ABC0137	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ABC0138	COG0081	regulation of translation
ABC0139	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ABC0140	COG0222	ribosome binding
ABC0141	COG2813	Specifically methylates the guanine in position
ABC0142	COG0085	RNA polymerase activity
ABC0143	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ABC0144	COG1358	cellular component organization or biogenesis
ABC0145	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABC0146	COG0049	tRNA binding
ABC0147	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABC0148	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABC0149	COG0051	transcription antitermination factor activity, RNA binding
ABC0150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ABC0151	COG0088	Forms part of the polypeptide exit tunnel
ABC0152	COG0089	rRNA binding
ABC0153	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ABC0154	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ABC0155	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ABC0156	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABC0157	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ABC0158	COG0255	Belongs to the universal ribosomal protein uL29 family
ABC0159	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ABC0160	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABC0161	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ABC0162	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ABC0163	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ABC0164	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ABC0165	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABC0166	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ABC0167	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABC0168	COG1841	ribosomal large subunit assembly
ABC0169	COG0200	Binds to the 23S rRNA
ABC0170	COG0201	protein transport
ABC0171	COG0563	adenylate kinase activity
ABC0172	COG0024	Methionine aminopeptidase
ABC0173	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABC0174	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ABC0175	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABC0176	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ABC0177	COG0202	RNA polymerase activity
ABC0178	COG0203	ribosomal protein L17
ABC0179	COG1122	ATPase activity
ABC0181	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ABC0182	COG0101	tRNA pseudouridine synthase activity
ABC0183	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABC0184	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABC0188	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ABC0192	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABC0193	COG3711	transcriptional antiterminator
ABC0194	COG1263	PTS System
ABC0194	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC0194	COG2190	(PTS) system
ABC0195	COG0489	protein tyrosine kinase activity
ABC0202	COG0726	polysaccharide deacetylase
ABC0205	COG2226	methyltransferase
ABC0206	COG0789	Transcriptional regulator
ABC0210	COG0789	Transcriptional regulator
ABC0219	COG3181	Tripartite tricarboxylate transporter family receptor
ABC0221	COG1454	alcohol dehydrogenase
ABC0222	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC0224	COG2217	Heavy metal translocating P-type atpase
ABC0226	COG1999	signal sequence binding
ABC0231	COG4172	Belongs to the ABC transporter superfamily
ABC0233	COG0601	transmembrane transport
ABC0234	COG0747	negative chemotaxis
ABC0235	COG1063	alcohol dehydrogenase
ABC0236	COG2755	lipolytic protein G-D-S-L family
ABC0237	COG0747	negative chemotaxis
ABC0239	COG1595	DNA-templated transcription, initiation
ABC0240	COG5662	AntiSigma factor
ABC0241	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ABC0243	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABC0245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABC0246	COG1917	Cupin 2, conserved barrel domain protein
ABC0246	COG2207	Transcriptional regulator
ABC0248	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ABC0250	COG1396	sequence-specific DNA binding
ABC0251	COG1819	glycosyl
ABC0252	COG1136	(ABC) transporter
ABC0253	COG0577	efflux transmembrane transporter activity
ABC0254	COG0745	RESPONSE REGULATOR receiver
ABC0256	COG1309	transcriptional regulator
ABC0257	COG2814	Major facilitator Superfamily
ABC0259	COG1136	(ABC) transporter
ABC0263	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABC0270	COG2072	flavoprotein involved in K transport
ABC0273	COG2226	methyltransferase
ABC0274	COG0180	Tryptophanyl-tRNA synthetase
ABC0276	COG0697	spore germination
ABC0282	COG1051	belongs to the nudix hydrolase family
ABC0284	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABC0285	COG0569	domain protein
ABC0286	COG2267	carboxylic ester hydrolase activity
ABC0287	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ABC0290	COG1528	Iron-storage protein
ABC0291	COG0628	permease
ABC0292	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ABC0292	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABC0302	COG1609	Transcriptional regulator
ABC0303	COG0789	Transcriptional regulator
ABC0304	COG1132	(ABC) transporter
ABC0305	COG1737	Transcriptional regulator
ABC0306	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABC0311	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ABC0312	COG1263	PTS System
ABC0312	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC0314	COG1609	Transcriptional regulator
ABC0315	COG2723	6-phospho-beta-galactosidase activity
ABC0316	COG1940	carbohydrate kinase activity
ABC0317	COG1175	transmembrane transport
ABC0318	COG0395	ABC-type sugar transport system, permease component
ABC0323	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
ABC0326	COG3829	transcription factor binding
ABC0326	COG3290	protein histidine kinase activity
ABC0327	COG1454	alcohol dehydrogenase
ABC0328	COG2610	gluconate transmembrane transporter activity
ABC0329	COG2066	Belongs to the glutaminase family
ABC0330	COG1454	alcohol dehydrogenase
ABC0331	COG1012	belongs to the aldehyde dehydrogenase family
ABC0332	COG0697	spore germination
ABC0334	COG0456	acetyltransferase
ABC0335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABC0336	COG1917	Cupin 2, conserved barrel domain protein
ABC0339	COG1175	transmembrane transport
ABC0340	COG0395	ABC-type sugar transport system, permease component
ABC0341	COG3842	ATPase activity
ABC0343	COG0318	PFAM AMP-dependent synthetase and ligase
ABC0344	COG0318	PFAM AMP-dependent synthetase and ligase
ABC0345	COG0183	Belongs to the thiolase family
ABC0346	COG1028	Short-chain dehydrogenase reductase Sdr
ABC0348	COG2814	Major facilitator Superfamily
ABC0349	COG1959	2 iron, 2 sulfur cluster binding
ABC0350	COG1017	nitric oxide dioxygenase activity
ABC0350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABC0351	COG0584	glycerophosphoryl diester phosphodiesterase
ABC0352	COG3842	ATPase activity
ABC0353	COG1175	transmembrane transport
ABC0354	COG0395	ABC-type sugar transport system, permease component
ABC0355	COG1653	transport
ABC0356	COG0584	glycerophosphoryl diester phosphodiesterase
ABC0360	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ABC0361	COG4209	transmembrane transport
ABC0362	COG0395	ABC-type sugar transport system, permease component
ABC0365	COG0673	inositol 2-dehydrogenase activity
ABC0366	COG0726	polysaccharide deacetylase
ABC0368	COG1028	Short-chain dehydrogenase reductase Sdr
ABC0371	COG0010	Belongs to the arginase family
ABC0374	COG4806	L-rhamnose isomerase
ABC0374	COG1070	Carbohydrate kinase
ABC0375	COG3347	Dehydrogenase
ABC0375	COG1028	Short-chain dehydrogenase reductase Sdr
ABC0376	COG3254	rhamnose metabolic process
ABC0377	COG2814	Major facilitator Superfamily
ABC0378	COG2207	Transcriptional regulator
ABC0379	COG0673	inositol 2-dehydrogenase activity
ABC0383	COG2972	Histidine kinase
ABC0384	COG2207	Transcriptional regulator
ABC0384	COG4753	response regulator
ABC0385	COG1653	transport
ABC0386	COG1175	transmembrane transport
ABC0387	COG0395	ABC-type sugar transport system, permease component
ABC0389	COG5002	protein histidine kinase activity
ABC0390	COG0745	RESPONSE REGULATOR receiver
ABC0391	COG0583	DNA-binding transcription factor activity
ABC0393	COG3401	FG-GAP repeat protein
ABC0395	COG1175	transmembrane transport
ABC0396	COG0395	ABC-type sugar transport system, permease component
ABC0399	COG1175	transmembrane transport
ABC0400	COG0395	ABC-type sugar transport system, permease component
ABC0401	COG5578	integral membrane protein
ABC0403	COG2207	Transcriptional regulator
ABC0404	COG0647	UMP catabolic process
ABC0405	COG0371	Dehydrogenase
ABC0407	COG1069	ribulokinase activity
ABC0408	COG2160	L-arabinose isomerase activity
ABC0409	COG4213	ABC transporter substrate-binding protein
ABC0410	COG1129	ABC transporter
ABC0411	COG4214	carbohydrate transport
ABC0412	COG1486	melibiose metabolic process
ABC0416	COG3279	Response regulator of the LytR AlgR family
ABC0417	COG2076	Multidrug Resistance protein
ABC0418	COG2076	Multidrug Resistance protein
ABC0419	COG1309	transcriptional regulator
ABC0420	COG2814	Major facilitator Superfamily
ABC0421	COG1349	DNA-binding transcription factor activity
ABC0422	COG1012	belongs to the aldehyde dehydrogenase family
ABC0423	COG3718	enzyme involved in inositol metabolism
ABC0424	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABC0425	COG3962	Belongs to the TPP enzyme family
ABC0426	COG1082	Xylose isomerase domain protein TIM barrel
ABC0427	COG0673	inositol 2-dehydrogenase activity
ABC0428	COG0191	fructose-bisphosphate aldolase activity
ABC0429	COG0673	inositol 2-dehydrogenase activity
ABC0430	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABC0431	COG2323	membrane
ABC0432	COG2873	o-acetylhomoserine
ABC0435	COG1175	transmembrane transport
ABC0436	COG1653	transport
ABC0438	COG1063	alcohol dehydrogenase
ABC0439	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC0441	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC0442	COG2721	sulfolactate sulfo-lyase activity
ABC0443	COG0246	Mannitol dehydrogenase
ABC0444	COG3711	transcriptional antiterminator
ABC0445	COG0191	fructose-bisphosphate aldolase activity
ABC0446	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC0446	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC0446	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC0447	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC0448	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC0448	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC0449	COG1917	Cupin 2, conserved barrel domain protein
ABC0450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC0451	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ABC0452	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ABC0453	COG3829	transcription factor binding
ABC0453	COG3290	protein histidine kinase activity
ABC0456	COG2851	Citrate transporter
ABC0457	COG0840	transmembrane signaling receptor activity
ABC0466	COG1312	Catalyzes the dehydration of D-mannonate
ABC0470	COG1012	belongs to the aldehyde dehydrogenase family
ABC0471	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC0472	COG2186	Transcriptional regulator
ABC0474	COG0463	Glycosyl transferase, family 2
ABC0474	COG0457	Tetratricopeptide repeat
ABC0476	COG2807	transmembrane transport
ABC0480	COG1357	PFAM Pentapeptide repeats (8 copies)
ABC0481	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABC0482	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABC0483	COG1447	Phosphotransferase system cellobiose-specific component IIA
ABC0484	COG2723	6-phospho-beta-galactosidase activity
ABC0485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC0485	COG3711	transcriptional antiterminator
ABC0489	COG1388	LysM domain
ABC0489	COG3584	3D domain protein
ABC0491	COG2188	Transcriptional regulator
ABC0492	COG4821	SIS domain
ABC0495	COG3850	Histidine kinase
ABC0495	COG5002	protein histidine kinase activity
ABC0496	COG3212	peptidase
ABC0497	COG3212	peptidase
ABC0500	COG0535	radical SAM domain protein
ABC0501	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABC0503	COG2226	methyltransferase
ABC0509	COG0438	transferase activity, transferring glycosyl groups
ABC0512	COG0438	transferase activity, transferring glycosyl groups
ABC0519	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABC0520	COG2755	lipolytic protein G-D-S-L family
ABC0522	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABC0524	COG4948	Mandelate Racemase Muconate Lactonizing
ABC0528	COG2205	protein histidine kinase activity
ABC0529	COG0745	RESPONSE REGULATOR receiver
ABC0532	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC0534	COG0655	NAD(P)H dehydrogenase (quinone) activity
ABC0536	COG0710	3-dehydroquinate dehydratase activity
ABC0544	COG4145	pantothenate transmembrane transporter activity
ABC0545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC0546	COG2186	Transcriptional regulator
ABC0547	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABC0549	COG1473	amidohydrolase
ABC0550	COG1464	Belongs to the NlpA lipoprotein family
ABC0551	COG2011	ABC-type metal ion transport system permease component
ABC0552	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABC0553	COG2207	Transcriptional regulator
ABC0553	COG0662	Cupin 2, conserved barrel domain protein
ABC0554	COG3507	Belongs to the glycosyl hydrolase 43 family
ABC0556	COG4209	transmembrane transport
ABC0557	COG0395	ABC-type sugar transport system, permease component
ABC0562	COG1228	amidohydrolase
ABC0563	COG1228	amidohydrolase
ABC0564	COG0747	negative chemotaxis
ABC0566	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC0567	COG0444	Belongs to the ABC transporter superfamily
ABC0568	COG4608	Belongs to the ABC transporter superfamily
ABC0570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC0571	COG1414	Transcriptional regulator
ABC0572	COG2115	Belongs to the xylose isomerase family
ABC0573	COG1070	Carbohydrate kinase
ABC0575	COG1940	carbohydrate kinase activity
ABC0577	COG0673	inositol 2-dehydrogenase activity
ABC0578	COG2508	Transcriptional regulator
ABC0583	COG4126	flavin adenine dinucleotide binding
ABC0585	COG0477	Major facilitator Superfamily
ABC0586	COG1942	4-Oxalocrotonate Tautomerase
ABC0589	COG0318	PFAM AMP-dependent synthetase and ligase
ABC0594	COG2258	MOSC domain
ABC0596	COG5583	Uncharacterized small protein (DUF2292)
ABC0597	COG0431	NADPH-dependent FMN reductase
ABC0598	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABC0599	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABC0600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC0601	COG1116	anion transmembrane transporter activity
ABC0604	COG1802	Transcriptional regulator
ABC0609	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC0611	COG0175	sulfate reduction
ABC0612	COG2046	Belongs to the sulfate adenylyltransferase family
ABC0613	COG0306	phosphate transporter
ABC0614	COG0529	Catalyzes the synthesis of activated sulfate
ABC0615	COG1587	Uroporphyrinogen-III synthase
ABC0615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABC0618	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ABC0619	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABC0621	COG1131	(ABC) transporter
ABC0622	COG2188	Transcriptional regulator
ABC0627	COG0583	DNA-binding transcription factor activity
ABC0628	COG0473	3-isopropylmalate dehydrogenase activity
ABC0629	COG1053	succinate dehydrogenase
ABC0630	COG1063	alcohol dehydrogenase
ABC0631	COG1312	Catalyzes the dehydration of D-mannonate
ABC0632	COG1028	Short-chain dehydrogenase reductase Sdr
ABC0633	COG0163	prenyltransferase activity
ABC0635	COG2814	Major facilitator Superfamily
ABC0636	COG0798	PFAM Bile acid sodium symporter
ABC0638	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ABC0640	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABC0641	COG1447	Phosphotransferase system cellobiose-specific component IIA
ABC0642	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABC0643	COG1486	melibiose metabolic process
ABC0644	COG3394	polysaccharide catabolic process
ABC0645	COG2188	Transcriptional regulator
ABC0648	COG5294	Protein conserved in bacteria
ABC0649	COG2271	Major facilitator Superfamily
ABC0650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABC0651	COG3844	kynureninase activity
ABC0657	COG0697	spore germination
ABC0658	COG1349	DNA-binding transcription factor activity
ABC0659	COG3395	kinase activity
ABC0660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABC0661	COG2610	gluconate transmembrane transporter activity
ABC0665	COG2851	Citrate transporter
ABC0666	COG4565	transcriptional regulatory protein
ABC0667	COG3290	protein histidine kinase activity
ABC0668	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC0669	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ABC0675	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ABC0676	COG0626	cystathionine gamma-synthase activity
ABC0677	COG3457	Alanine racemase
ABC0678	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ABC0679	COG2214	Heat shock protein DnaJ domain protein
ABC0680	COG0443	Heat shock 70 kDa protein
ABC0681	COG1028	Short-chain dehydrogenase reductase Sdr
ABC0682	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABC0683	COG1119	ATPase activity
ABC0686	COG1175	transmembrane transport
ABC0687	COG0395	ABC-type sugar transport system, permease component
ABC0688	COG4842	Belongs to the WXG100 family
ABC0690	COG4499	WXG100 protein secretion system (Wss), protein YukC
ABC0691	COG1674	ftsk spoiiie
ABC0692	COG1511	domain protein
ABC0707	COG1136	(ABC) transporter
ABC0711	COG1737	Transcriptional regulator
ABC0712	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ABC0713	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC0713	COG2190	(PTS) system
ABC0713	COG1263	PTS System
ABC0714	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABC0715	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ABC0716	COG1140	nitrate reductase beta subunit
ABC0718	COG2181	nitrate reductase activity
ABC0721	COG2197	response regulator
ABC0722	COG2223	nitrite transmembrane transporter activity
ABC0725	COG2972	Histidine kinase
ABC0726	COG2207	Transcriptional regulator
ABC0726	COG4753	response regulator
ABC0727	COG4209	transmembrane transport
ABC0728	COG0395	ABC-type sugar transport system, permease component
ABC0730	COG1191	sigma factor activity
ABC0731	COG0586	Pfam SNARE associated Golgi protein
ABC0732	COG1486	melibiose metabolic process
ABC0733	COG2207	Transcriptional regulator
ABC0734	COG3239	Fatty acid desaturase
ABC0735	COG4585	Histidine kinase
ABC0736	COG2197	response regulator
ABC0737	COG2239	Acts as a magnesium transporter
ABC0738	COG1846	Transcriptional regulator
ABC0741	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC0742	COG0456	acetyltransferase
ABC0743	COG0024	Methionine aminopeptidase
ABC0745	COG1929	Belongs to the glycerate kinase type-1 family
ABC0746	COG3835	regulator
ABC0749	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABC0751	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ABC0752	COG1404	Belongs to the peptidase S8 family
ABC0755	COG2818	Glycosylase
ABC0756	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ABC0758	COG0861	Integral membrane protein TerC family
ABC0759	COG0596	Alpha beta hydrolase
ABC0760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ABC0761	COG1404	Belongs to the peptidase S8 family
ABC0763	COG1876	peptidase activity
ABC0764	COG0531	amino acid
ABC0766	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ABC0766	COG2508	Transcriptional regulator
ABC0767	COG0686	Belongs to the AlaDH PNT family
ABC0768	COG2706	6-phosphogluconolactonase activity
ABC0769	COG2962	Rard protein
ABC0771	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC0772	COG0765	amino acid transport
ABC0773	COG0765	amino acid transport
ABC0774	COG0784	Response regulator, receiver
ABC0775	COG4191	Histidine kinase
ABC0776	COG2362	D-Aminopeptidase
ABC0777	COG0601	transmembrane transport
ABC0778	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC0779	COG0444	Belongs to the ABC transporter superfamily
ABC0780	COG4166	transmembrane transport
ABC0781	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABC0782	COG0791	NLP P60 protein
ABC0783	COG4608	Belongs to the ABC transporter superfamily
ABC0784	COG1733	regulation of RNA biosynthetic process
ABC0786	COG2205	protein histidine kinase activity
ABC0787	COG2111	Na H antiporter
ABC0787	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABC0788	COG2111	Na H antiporter
ABC0789	COG1006	Multisubunit Na H antiporter MnhC subunit
ABC0790	COG0651	ATP synthesis coupled electron transport
ABC0791	COG1863	multisubunit Na H antiporter MnhE subunit
ABC0792	COG2212	antiporter activity
ABC0793	COG1320	monovalent cation:proton antiporter activity
ABC0795	COG1082	Xylose isomerase domain protein TIM barrel
ABC0796	COG0673	inositol 2-dehydrogenase activity
ABC0798	COG3214	Protein conserved in bacteria
ABC0799	COG5578	integral membrane protein
ABC0801	COG1876	peptidase activity
ABC0802	COG1368	sulfuric ester hydrolase activity
ABC0804	COG0705	Rhomboid family
ABC0805	COG0736	holo-[acyl-carrier-protein] synthase activity
ABC0806	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ABC0807	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABC0808	COG0864	Transcriptional regulator
ABC0809	COG2337	Toxic component of a toxin-antitoxin (TA) module
ABC0810	COG1366	Belongs to the anti-sigma-factor antagonist family
ABC0811	COG1366	Belongs to the anti-sigma-factor antagonist family
ABC0812	COG2172	sigma factor antagonist activity
ABC0813	COG2208	phosphoserine phosphatase activity
ABC0814	COG1366	Belongs to the anti-sigma-factor antagonist family
ABC0815	COG2172	sigma factor antagonist activity
ABC0816	COG1191	sigma factor activity
ABC0818	COG2183	response to ionizing radiation
ABC0820	COG3091	SprT-like family
ABC0823	COG3328	transposase activity
ABC0824	COG4282	regulation of fungal-type cell wall biogenesis
ABC0825	COG0662	Cupin 2, conserved barrel domain protein
ABC0826	COG2816	NAD+ diphosphatase activity
ABC0830	COG1278	Cold shock
ABC0831	COG1329	Transcriptional regulator
ABC0832	COG0640	Transcriptional regulator
ABC0834	COG0346	lactoylglutathione lyase activity
ABC0835	COG0640	Transcriptional regulator
ABC0836	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABC0837	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABC0838	COG2140	Oxalate decarboxylase
ABC0839	COG2514	catechol 2,3-dioxygenase activity
ABC0840	COG1802	Transcriptional regulator
ABC0841	COG0473	3-isopropylmalate dehydrogenase activity
ABC0849	COG5646	InterPro IPR014922
ABC0850	COG1687	branched-chain amino acid
ABC0851	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ABC0856	COG0384	phenazine biosynthesis protein PhzF
ABC0857	COG3711	transcriptional antiterminator
ABC0857	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC0859	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC0859	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC0859	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC0863	COG1285	pathogenesis
ABC0864	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABC0865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABC0866	COG0626	cystathionine gamma-synthase activity
ABC0867	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ABC0868	COG0802	atpase or kinase
ABC0869	COG1214	PFAM Peptidase M22, glycoprotease
ABC0870	COG0456	acetyltransferase
ABC0871	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ABC0872	COG0488	(ABC) transporter
ABC0873	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ABC0874	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABC0875	COG0805	protein transport
ABC0876	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABC0877	COG2011	ABC-type metal ion transport system permease component
ABC0878	COG1464	Belongs to the NlpA lipoprotein family
ABC0879	COG0371	Dehydrogenase
ABC0880	COG1266	CAAX protease self-immunity
ABC0881	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ABC0882	COG0459	protein refolding
ABC0887	COG4821	SIS domain
ABC0888	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ABC0889	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ABC0890	COG2368	4-hydroxyphenylacetate
ABC0891	COG0315	cyclic pyranopterin monophosphate synthase activity
ABC0892	COG0746	molybdenum cofactor guanylyltransferase activity
ABC0894	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABC0895	COG0303	'Molybdopterin
ABC0896	COG1763	Mo-molybdopterin cofactor biosynthetic process
ABC0897	COG0314	molybdopterin synthase activity
ABC0898	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ABC0899	COG2116	formate transmembrane transporter activity
ABC0900	COG3383	formate dehydrogenase (NAD+) activity
ABC0902	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ABC0905	COG4485	Bacterial membrane protein, YfhO
ABC0907	COG0463	Glycosyl transferase, family 2
ABC0911	COG0765	amino acid transport
ABC0912	COG0765	amino acid transport
ABC0913	COG1126	abc transporter atp-binding protein
ABC0914	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ABC0915	COG3290	protein histidine kinase activity
ABC0916	COG4565	transcriptional regulatory protein
ABC0917	COG3493	citrate carrier protein
ABC0918	COG0281	malic enzyme
ABC0926	COG4824	toxin secretion phage lysis holin
ABC0928	COG0778	Nitroreductase
ABC0929	COG0768	penicillin binding
ABC0931	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABC0933	COG0714	Associated with various cellular activities
ABC0934	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
ABC0935	COG1305	Transglutaminase-like
ABC0936	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABC0936	COG0519	Catalyzes the synthesis of GMP from XMP
ABC0943	COG1136	(ABC) transporter
ABC0944	COG0577	efflux transmembrane transporter activity
ABC0945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC0948	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABC0949	COG2814	Major facilitator Superfamily
ABC0950	COG1846	Transcriptional regulator
ABC0952	COG2376	Dihydroxyacetone kinase
ABC0954	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ABC0959	COG2252	PERMEase
ABC0962	COG1408	metallophosphoesterase
ABC0964	COG3290	protein histidine kinase activity
ABC0964	COG3829	transcription factor binding
ABC0965	COG1012	belongs to the aldehyde dehydrogenase family
ABC0966	COG0737	Belongs to the 5'-nucleotidase family
ABC0967	COG1476	TRANSCRIPTIONal
ABC0969	COG1335	isochorismatase
ABC0970	COG0326	Molecular chaperone. Has ATPase activity
ABC0971	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ABC0972	COG2124	cytochrome p450
ABC0974	COG1620	l-lactate permease
ABC0975	COG0247	lactate metabolic process
ABC0976	COG1139	Iron-sulfur cluster binding protein
ABC0977	COG1556	Lactate utilization protein
ABC0978	COG2186	Transcriptional regulator
ABC0979	COG1454	alcohol dehydrogenase
ABC0980	COG1012	belongs to the aldehyde dehydrogenase family
ABC0981	COG1510	regulation of RNA biosynthetic process
ABC0985	COG3764	Sortase (surface protein transpeptidase)
ABC0988	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABC0989	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ABC0990	COG2059	Chromate
ABC0991	COG2059	Chromate
ABC0992	COG1349	DNA-binding transcription factor activity
ABC0993	COG1028	Short-chain dehydrogenase reductase Sdr
ABC0994	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ABC0995	COG1904	glucuronate isomerase
ABC0996	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABC0997	COG0789	Transcriptional regulator
ABC0998	COG3424	synthase
ABC0999	COG1755	Isoprenylcysteine carboxyl methyltransferase
ABC1003	COG1132	(ABC) transporter
ABC1004	COG1132	(ABC) transporter
ABC1009	COG1191	sigma factor activity
ABC1010	COG0025	NhaP-type Na H and K H
ABC1011	COG3290	protein histidine kinase activity
ABC1012	COG4565	transcriptional regulatory protein
ABC1017	COG3654	unkown
ABC1024	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABC1025	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ABC1026	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABC1027	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ABC1028	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABC1029	COG0047	phosphoribosylformylglycinamidine synthase activity
ABC1030	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABC1031	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ABC1032	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ABC1033	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ABC1034	COG0138	bifunctional purine biosynthesis protein purh
ABC1035	COG0151	Belongs to the GarS family
ABC1037	COG1609	Transcriptional regulator
ABC1038	COG1028	Short-chain dehydrogenase reductase Sdr
ABC1039	COG1063	alcohol dehydrogenase
ABC1041	COG1028	Short-chain dehydrogenase reductase Sdr
ABC1044	COG4585	Histidine kinase
ABC1045	COG2197	response regulator
ABC1046	COG1131	(ABC) transporter
ABC1070	COG1510	regulation of RNA biosynthetic process
ABC1074	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABC1075	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ABC1076	COG4496	protein, YerC YecD
ABC1077	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ABC1082	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC1083	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC1084	COG1120	ATPase activity
ABC1085	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ABC1086	COG0210	DNA helicase
ABC1087	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABC1088	COG4851	CamS sex pheromone cAM373 precursor
ABC1089	COG1744	ABC transporter substrate-binding protein PnrA-like
ABC1090	COG3845	ABC transporter
ABC1091	COG4603	Belongs to the binding-protein-dependent transport system permease family
ABC1092	COG1079	Belongs to the binding-protein-dependent transport system permease family
ABC1095	COG2318	DinB family
ABC1096	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABC1097	COG0154	amidase activity
ABC1098	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABC1099	COG1597	lipid kinase activity
ABC1100	COG0716	FMN binding
ABC1101	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABC1103	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC1108	COG0789	Transcriptional regulator
ABC1110	COG0129	dihydroxy-acid dehydratase activity
ABC1111	COG1414	Transcriptional regulator
ABC1113	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC1114	COG1012	belongs to the aldehyde dehydrogenase family
ABC1115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABC1116	COG1121	(ABC) transporter
ABC1117	COG3443	Belongs to the bacterial solute-binding protein 9 family
ABC1117	COG0803	Belongs to the bacterial solute-binding protein 9 family
ABC1118	COG3443	Belongs to the bacterial solute-binding protein 9 family
ABC1119	COG0523	cobalamin synthesis protein
ABC1121	COG3340	Belongs to the peptidase S51 family
ABC1122	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABC1123	COG2207	Transcriptional regulator
ABC1124	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC1128	COG2721	sulfolactate sulfo-lyase activity
ABC1129	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ABC1130	COG1846	Transcriptional regulator
ABC1130	COG1940	carbohydrate kinase activity
ABC1132	COG1501	Belongs to the glycosyl hydrolase 31 family
ABC1133	COG2972	Histidine kinase
ABC1134	COG4753	response regulator
ABC1134	COG2207	Transcriptional regulator
ABC1135	COG4209	transmembrane transport
ABC1136	COG0395	ABC-type sugar transport system, permease component
ABC1139	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABC1141	COG3250	beta-galactosidase activity
ABC1141	COG5297	Belongs to the glycosyl hydrolase family 6
ABC1143	COG2207	Transcriptional regulator
ABC1144	COG1653	transport
ABC1145	COG4209	transmembrane transport
ABC1146	COG0395	ABC-type sugar transport system, permease component
ABC1149	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ABC1151	COG5578	integral membrane protein
ABC1152	COG0673	inositol 2-dehydrogenase activity
ABC1153	COG2721	sulfolactate sulfo-lyase activity
ABC1154	COG0246	Mannitol dehydrogenase
ABC1158	COG3732	PTS system glucitol sorbitol-specific
ABC1160	COG1028	Short-chain dehydrogenase reductase Sdr
ABC1161	COG3397	chitin binding
ABC1163	COG3328	transposase activity
ABC1164	COG3764	Sortase (surface protein transpeptidase)
ABC1166	COG2610	gluconate transmembrane transporter activity
ABC1168	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABC1169	COG0745	RESPONSE REGULATOR receiver
ABC1170	COG2205	protein histidine kinase activity
ABC1171	COG1131	(ABC) transporter
ABC1173	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABC1174	COG0640	Transcriptional regulator
ABC1175	COG1686	Belongs to the peptidase S11 family
ABC1178	COG0010	Belongs to the arginase family
ABC1181	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABC1182	COG2423	ornithine cyclodeaminase activity
ABC1183	COG5577	PFAM Coat F domain
ABC1184	COG1113	amino acid transport
ABC1185	COG1280	lysine exporter protein (LysE YggA)
ABC1186	COG3546	catalase activity
ABC1199	COG3011	Protein conserved in bacteria
ABC1200	COG2318	DinB family
ABC1201	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC1202	COG1279	arginine transmembrane transporter activity
ABC1203	COG1522	sequence-specific DNA binding
ABC1205	COG3328	transposase activity
ABC1210	COG1131	(ABC) transporter
ABC1214	COG1175	transmembrane transport
ABC1215	COG0395	ABC-type sugar transport system, permease component
ABC1217	COG1396	sequence-specific DNA binding
ABC1219	COG0747	negative chemotaxis
ABC1221	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABC1222	COG0385	Bile acid
ABC1223	COG0277	FAD linked oxidase domain protein
ABC1224	COG5002	protein histidine kinase activity
ABC1225	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ABC1226	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ABC1228	COG4208	sulfate ABC transporter
ABC1231	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABC1232	COG4120	Belongs to the binding-protein-dependent transport system permease family
ABC1234	COG2391	methyltransferase activity
ABC1235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABC1238	COG0444	Belongs to the ABC transporter superfamily
ABC1239	COG4608	Belongs to the ABC transporter superfamily
ABC1240	COG0747	negative chemotaxis
ABC1241	COG0601	transmembrane transport
ABC1242	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC1247	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ABC1248	COG3639	organic phosphonate transmembrane transporter activity
ABC1249	COG3639	organic phosphonate transmembrane transporter activity
ABC1250	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ABC1252	COG3973	AAA domain
ABC1253	COG1132	(ABC) transporter
ABC1254	COG1132	(ABC) transporter
ABC1257	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ABC1258	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ABC1259	COG1115	amino acid carrier protein
ABC1260	COG2244	polysaccharide biosynthetic process
ABC1261	COG1649	PFAM Uncharacterised BCR, COG1649
ABC1263	COG1263	PTS System
ABC1263	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC1264	COG0366	Alpha amylase catalytic
ABC1265	COG2188	Transcriptional regulator
ABC1267	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ABC1268	COG0488	(ABC) transporter
ABC1269	COG1349	DNA-binding transcription factor activity
ABC1270	COG1105	Belongs to the carbohydrate kinase PfkB family
ABC1271	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC1271	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC1271	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC1272	COG1077	Cell shape determining protein MreB Mrl
ABC1273	COG0733	neurotransmitter:sodium symporter activity
ABC1275	COG2002	toxin-antitoxin pair type II binding
ABC1278	COG3341	Caulimovirus viroplasmin
ABC1278	COG0328	RNA-DNA hybrid ribonuclease activity
ABC1279	COG1012	belongs to the aldehyde dehydrogenase family
ABC1283	COG0753	catalase activity
ABC1284	COG1164	Oligoendopeptidase f
ABC1286	COG1294	oxidase, subunit
ABC1287	COG1271	oxidase subunit
ABC1292	COG0535	radical SAM domain protein
ABC1294	COG1253	flavin adenine dinucleotide binding
ABC1296	COG0726	polysaccharide deacetylase
ABC1297	COG0445	tRNA wobble uridine modification
ABC1300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABC1301	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABC1303	COG1090	epimerase
ABC1304	COG2137	regulation of response to DNA damage stimulus
ABC1308	COG1988	membrane-bound metal-dependent
ABC1310	COG1028	Short-chain dehydrogenase reductase Sdr
ABC1313	COG1028	Short-chain dehydrogenase reductase Sdr
ABC1315	COG3557	Belongs to the UPF0374 family
ABC1316	COG1132	(ABC) transporter
ABC1317	COG4129	membrane
ABC1318	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABC1319	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABC1320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABC1322	COG0735	belongs to the Fur family
ABC1324	COG5434	Belongs to the glycosyl hydrolase 28 family
ABC1325	COG4974	Belongs to the 'phage' integrase family
ABC1341	COG3953	SLT domain
ABC1341	COG5280	Phage tail tape measure protein TP901
ABC1343	COG5434	Belongs to the glycosyl hydrolase 28 family
ABC1350	COG4824	toxin secretion phage lysis holin
ABC1351	COG3409	Peptidoglycan-binding domain 1 protein
ABC1351	COG5632	N-Acetylmuramoyl-L-alanine amidase
ABC1381	COG0640	Transcriptional regulator
ABC1382	COG2814	Major facilitator Superfamily
ABC1383	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABC1385	COG1846	Transcriptional regulator
ABC1386	COG0396	ATPase activity
ABC1387	COG0596	Alpha beta hydrolase
ABC1389	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABC1391	COG1959	2 iron, 2 sulfur cluster binding
ABC1392	COG0477	Major facilitator Superfamily
ABC1395	COG0789	Transcriptional regulator
ABC1396	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ABC1402	COG3328	transposase activity
ABC1407	COG3964	amidohydrolase
ABC1422	COG2267	carboxylic ester hydrolase activity
ABC1427	COG1733	regulation of RNA biosynthetic process
ABC1428	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABC1432	COG4585	Histidine kinase
ABC1433	COG2197	response regulator
ABC1434	COG1131	(ABC) transporter
ABC1437	COG1442	glycosyl transferase family 8
ABC1438	COG4894	glucomannan catabolic process
ABC1440	COG0584	glycerophosphoryl diester phosphodiesterase
ABC1443	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABC1445	COG0737	Belongs to the 5'-nucleotidase family
ABC1447	COG1405	negative regulation of cell septum assembly
ABC1447	COG3012	SEC-C Motif Domain Protein
ABC1448	COG0471	metal ion transport
ABC1450	COG1966	Carbon starvation protein
ABC1452	COG1012	belongs to the aldehyde dehydrogenase family
ABC1453	COG1263	PTS System
ABC1453	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC1455	COG1621	beta-fructofuranosidase activity
ABC1456	COG1917	Cupin 2, conserved barrel domain protein
ABC1456	COG2207	Transcriptional regulator
ABC1458	COG1131	(ABC) transporter
ABC1460	COG1725	Transcriptional regulator
ABC1461	COG1131	(ABC) transporter
ABC1463	COG1363	Peptidase, m42
ABC1464	COG0783	Belongs to the Dps family
ABC1467	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABC1470	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ABC1473	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABC1474	COG2766	serine protein kinase
ABC1477	COG2718	Belongs to the UPF0229 family
ABC1479	COG2814	Major facilitator Superfamily
ABC1484	COG1028	Short-chain dehydrogenase reductase Sdr
ABC1486	COG2188	Transcriptional regulator
ABC1487	COG0165	Argininosuccinate lyase
ABC1488	COG2188	Transcriptional regulator
ABC1489	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ABC1490	COG0363	glucosamine-6-phosphate deaminase activity
ABC1492	COG0436	Aminotransferase
ABC1493	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABC1494	COG0584	glycerophosphoryl diester phosphodiesterase
ABC1495	COG0438	transferase activity, transferring glycosyl groups
ABC1496	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABC1496	COG3153	acetyltransferase
ABC1497	COG1489	DNA binding
ABC1498	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ABC1499	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABC1500	COG2719	SpoVR family
ABC1501	COG1132	(ABC) transporter
ABC1502	COG1132	(ABC) transporter
ABC1503	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC1505	COG1704	LemA family
ABC1506	COG1960	acyl-CoA dehydrogenase activity
ABC1507	COG0439	Biotin carboxylase
ABC1508	COG0511	ligase activity, forming carbon-carbon bonds
ABC1509	COG1024	Enoyl-CoA hydratase
ABC1510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABC1514	COG3842	ATPase activity
ABC1515	COG2508	Transcriptional regulator
ABC1518	COG4399	Belongs to the UPF0754 family
ABC1519	COG3679	Belongs to the UPF0342 family
ABC1520	COG0561	phosphatase activity
ABC1523	COG0745	RESPONSE REGULATOR receiver
ABC1524	COG2205	protein histidine kinase activity
ABC1524	COG2770	Histidine kinase
ABC1525	COG3481	metal-dependent phosphohydrolase, HD sub domain
ABC1527	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABC1529	COG1846	Transcriptional regulator
ABC1531	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ABC1532	COG0537	adenosine 5'-monophosphoramidase activity
ABC1533	COG1131	(ABC) transporter
ABC1534	COG4473	ABC transporter
ABC1536	COG0785	Cytochrome C biogenesis protein
ABC1537	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABC1538	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ABC1539	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABC1540	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ABC1541	COG3290	protein histidine kinase activity
ABC1542	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABC1543	COG4492	Belongs to the UPF0735 family
ABC1544	COG0077	Prephenate dehydratase
ABC1545	COG1827	regulation of RNA biosynthetic process
ABC1546	COG1104	cysteine desulfurase activity
ABC1547	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ABC1548	COG0157	Belongs to the NadC ModD family
ABC1549	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ABC1550	COG1388	LysM domain
ABC1554	COG0632	four-way junction helicase activity
ABC1555	COG2255	four-way junction helicase activity
ABC1557	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABC1558	COG0343	queuine tRNA-ribosyltransferase activity
ABC1559	COG1862	Preprotein translocase
ABC1563	COG2244	polysaccharide biosynthetic process
ABC1565	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABC1565	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABC1566	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABC1566	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABC1567	COG5416	Lipopolysaccharide assembly protein A domain
ABC1568	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABC1568	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ABC1569	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABC1570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABC1571	COG1490	D-aminoacyl-tRNA deacylase activity
ABC1572	COG1609	Transcriptional regulator
ABC1574	COG0673	inositol 2-dehydrogenase activity
ABC1575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ABC1576	COG0124	histidyl-tRNA synthetase
ABC1577	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ABC1580	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ABC1581	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ABC1583	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABC1584	COG1959	2 iron, 2 sulfur cluster binding
ABC1585	COG1104	cysteine desulfurase activity
ABC1586	COG0482	sulfurtransferase activity
ABC1588	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABC1589	COG3881	PFAM PRC-barrel domain
ABC1591	COG0628	permease
ABC1592	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABC1593	COG4472	Bacterial protein of unknown function (DUF965)
ABC1594	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABC1595	COG3906	Belongs to the UPF0473 family
ABC1596	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ABC1597	COG4122	O-methyltransferase activity
ABC1598	COG0572	uridine kinase
ABC1599	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABC1601	COG1793	dna ligase
ABC1601	COG3285	dna ligase
ABC1602	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ABC1603	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABC1605	COG0747	negative chemotaxis
ABC1606	COG4608	Belongs to the ABC transporter superfamily
ABC1607	COG0444	Belongs to the ABC transporter superfamily
ABC1608	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC1609	COG0601	transmembrane transport
ABC1610	COG1309	transcriptional regulator
ABC1611	COG0366	Alpha amylase catalytic
ABC1613	COG0095	Lipoate-protein ligase
ABC1614	COG1288	antiporter activity
ABC1616	COG0385	Bile acid
ABC1620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABC1620	COG1587	Uroporphyrinogen-III synthase
ABC1621	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABC1622	COG2146	nitrite reductase [NAD(P)H] activity
ABC1623	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABC1624	COG0243	molybdopterin cofactor binding
ABC1625	COG2223	nitrite transmembrane transporter activity
ABC1626	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABC1628	COG0776	regulation of translation
ABC1629	COG1320	monovalent cation:proton antiporter activity
ABC1630	COG2212	antiporter activity
ABC1631	COG1863	multisubunit Na H antiporter MnhE subunit
ABC1632	COG0651	ATP synthesis coupled electron transport
ABC1633	COG1006	Multisubunit Na H antiporter MnhC subunit
ABC1634	COG2111	Na H antiporter
ABC1635	COG2111	Na H antiporter
ABC1635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABC1636	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ABC1637	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ABC1638	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ABC1639	COG1534	Rna-binding protein
ABC1640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ABC1641	COG1713	HD superfamily hydrolase involved in NAD metabolism
ABC1642	COG0799	negative regulation of ribosome biogenesis
ABC1643	COG2996	Protein conserved in bacteria
ABC1644	COG2226	methyltransferase
ABC1645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ABC1646	COG1555	photosystem II stabilization
ABC1646	COG1596	polysaccharide export
ABC1647	COG2131	deaminase
ABC1648	COG2333	competence protein COMEC
ABC1648	COG0658	competence protein
ABC1650	COG1466	dna polymerase III delta subunit
ABC1651	COG0268	Binds directly to 16S ribosomal RNA
ABC1652	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ABC1653	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABC1655	COG0481	GTPase activity
ABC1656	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABC1657	COG1420	regulation of RNA biosynthetic process
ABC1658	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ABC1659	COG0443	Heat shock 70 kDa protein
ABC1660	COG0484	heat shock protein binding
ABC1661	COG2264	protein methyltransferase activity
ABC1662	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABC1663	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABC1664	COG2226	methyltransferase
ABC1665	COG1301	dicarboxylic acid transport
ABC1666	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ABC1667	COG0667	Aldo Keto reductase
ABC1668	COG1283	sodium-dependent phosphate transmembrane transporter activity
ABC1669	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABC1670	COG1610	YqeY-like protein
ABC1671	COG1030	water channel activity
ABC1672	COG4864	UPF0365 protein
ABC1676	COG1702	phosphate starvation-inducible protein PhoH
ABC1677	COG1480	7TM receptor with intracellular HD hydrolase
ABC1678	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ABC1679	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ABC1680	COG0295	cytidine deaminase activity
ABC1681	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABC1683	COG1381	Involved in DNA repair and RecF pathway recombination
ABC1684	COG0752	glycyl-tRNA synthetase alpha subunit
ABC1685	COG0751	glycine-tRNA ligase activity
ABC1686	COG0517	IMP dehydrogenase activity
ABC1687	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ABC1688	COG1671	Belongs to the UPF0178 family
ABC1689	COG0358	DNA primase activity
ABC1690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABC1691	COG2010	Cytochrome c
ABC1692	COG2384	SAM-dependent methyltransferase
ABC1693	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABC1694	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ABC1695	COG1329	Transcriptional regulator
ABC1697	COG0513	Belongs to the DEAD box helicase family
ABC1698	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ABC1700	COG5002	protein histidine kinase activity
ABC1702	COG1121	(ABC) transporter
ABC1703	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABC1704	COG0735	belongs to the Fur family
ABC1706	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
ABC1707	COG4709	membrane
ABC1708	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ABC1710	COG2814	Major facilitator Superfamily
ABC1711	COG4086	secreted protein
ABC1714	COG0704	Plays a role in the regulation of phosphate uptake
ABC1715	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABC1716	COG0477	Major facilitator Superfamily
ABC1717	COG0768	penicillin binding
ABC1721	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ABC1722	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ABC1724	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ABC1725	COG1757	Na H antiporter
ABC1726	COG0705	Rhomboid family
ABC1726	COG0457	Tetratricopeptide repeat
ABC1727	COG0697	spore germination
ABC1731	COG1940	carbohydrate kinase activity
ABC1732	COG1027	Aspartate ammonia-lyase
ABC1733	COG0352	thiamine-phosphate diphosphorylase activity
ABC1735	COG2022	thiamine diphosphate biosynthetic process
ABC1736	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC1737	COG0351	phosphomethylpyrimidine kinase
ABC1737	COG0352	thiamine-phosphate diphosphorylase activity
ABC1739	COG0011	TIGRFAM Protein of
ABC1740	COG2153	protein acetylation
ABC1741	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ABC1742	COG2382	esterase
ABC1744	COG1396	sequence-specific DNA binding
ABC1745	COG1396	sequence-specific DNA binding
ABC1746	COG0114	fumarate hydratase activity
ABC1747	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABC1748	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABC1749	COG3852	Histidine kinase
ABC1750	COG4129	membrane
ABC1751	COG1376	ErfK ybiS ycfS ynhG family protein
ABC1752	COG0346	lactoylglutathione lyase activity
ABC1753	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABC1754	COG1728	Protein conserved in bacteria
ABC1756	COG0517	IMP dehydrogenase activity
ABC1759	COG2861	carbohydrate metabolic process
ABC1760	COG0789	Transcriptional regulator
ABC1763	COG0527	aspartate kinase activity
ABC1765	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ABC1766	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ABC1767	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABC1768	COG0367	asparagine synthase
ABC1772	COG1510	regulation of RNA biosynthetic process
ABC1773	COG2190	(PTS) system
ABC1774	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
ABC1775	COG1850	ribulose-bisphosphate carboxylase activity
ABC1776	COG1968	undecaprenyl-diphosphatase activity
ABC1777	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC1778	COG0494	nUDIX hydrolase
ABC1779	COG1300	Membrane
ABC1780	COG0735	belongs to the Fur family
ABC1782	COG4974	Belongs to the 'phage' integrase family
ABC1783	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ABC1785	COG1764	response to oxidative stress
ABC1787	COG2814	Major facilitator Superfamily
ABC1790	COG1988	membrane-bound metal-dependent
ABC1792	COG1686	Belongs to the peptidase S11 family
ABC1794	COG2172	sigma factor antagonist activity
ABC1797	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABC1800	COG0697	spore germination
ABC1801	COG0019	diaminopimelate decarboxylase activity
ABC1802	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABC1803	COG0583	DNA-binding transcription factor activity
ABC1805	COG0372	Belongs to the citrate synthase family
ABC1806	COG2079	MmgE PrpD family protein
ABC1807	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ABC1808	COG2084	Dehydrogenase
ABC1809	COG1012	belongs to the aldehyde dehydrogenase family
ABC1810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ABC1811	COG0307	riboflavin synthase, alpha
ABC1812	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABC1812	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABC1813	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABC1814	COG1547	Domain of unknown function (DUF309)
ABC1815	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ABC1816	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ABC1818	COG1012	belongs to the aldehyde dehydrogenase family
ABC1819	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABC1820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC1821	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABC1823	COG2323	membrane
ABC1826	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABC1828	COG1686	Belongs to the peptidase S11 family
ABC1829	COG2715	membrane protein required for spore maturation
ABC1830	COG0700	Nucleoside recognition
ABC1831	COG1187	pseudouridine synthase activity
ABC1832	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC1833	COG1333	cytochrome c biogenesis protein
ABC1834	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABC1835	COG0745	RESPONSE REGULATOR receiver
ABC1836	COG5002	protein histidine kinase activity
ABC1837	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC1838	COG1120	ATPase activity
ABC1841	COG0861	Integral membrane protein TerC family
ABC1842	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABC1843	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABC1845	COG4955	Helix-turn-helix domain
ABC1846	COG0514	ATP-dependent DNA helicase (RecQ)
ABC1847	COG1266	CAAX protease self-immunity
ABC1852	COG0438	transferase activity, transferring glycosyl groups
ABC1853	COG0438	transferase activity, transferring glycosyl groups
ABC1855	COG1473	amidohydrolase
ABC1856	COG1408	metallophosphoesterase
ABC1857	COG0789	Transcriptional regulator
ABC1858	COG4862	establishment of competence for transformation
ABC1859	COG0745	RESPONSE REGULATOR receiver
ABC1860	COG5002	protein histidine kinase activity
ABC1862	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABC1863	COG0492	ferredoxin-NADP+ reductase activity
ABC1865	COG2339	peptidase activity
ABC1867	COG0626	cystathionine gamma-synthase activity
ABC1868	COG0646	methionine synthase
ABC1868	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ABC1869	COG0646	methionine synthase
ABC1869	COG1410	methionine synthase
ABC1870	COG3409	Peptidoglycan-binding domain 1 protein
ABC1870	COG3773	Cell wall hydrolase
ABC1871	COG2959	enzyme of heme biosynthesis
ABC1872	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ABC1873	COG0204	Acyl-transferase
ABC1874	COG0539	negative regulation of cytoplasmic translation
ABC1876	COG1160	GTP binding
ABC1877	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ABC1878	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ABC1882	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ABC1883	COG0302	gtp cyclohydrolase
ABC1885	COG0142	geranyltranstransferase activity
ABC1886	COG2226	methyltransferase
ABC1887	COG0109	protoheme IX farnesyltransferase activity
ABC1889	COG0142	geranyltranstransferase activity
ABC1890	COG0105	UTP biosynthetic process
ABC1891	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ABC1892	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ABC1893	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ABC1894	COG4401	Chorismate mutase type I
ABC1896	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABC1897	COG0134	indole-3-glycerol-phosphate synthase activity
ABC1898	COG0135	phosphoribosylanthranilate isomerase activity
ABC1899	COG0133	tryptophan synthase activity
ABC1900	COG0159	tryptophan synthase activity
ABC1901	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABC1902	COG0287	Prephenate dehydrogenase
ABC1903	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABC1904	COG0457	Tetratricopeptide repeat
ABC1905	COG5582	Belongs to the UPF0302 family
ABC1907	COG0723	plastoquinol--plastocyanin reductase activity
ABC1908	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ABC1910	COG4347	Protein of unknown function (DUF1405)
ABC1912	COG2738	Putative neutral zinc metallopeptidase
ABC1913	COG2814	Major facilitator Superfamily
ABC1914	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABC1915	COG1694	Mazg nucleotide pyrophosphohydrolase
ABC1916	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ABC1917	COG1803	Methylglyoxal synthase
ABC1919	COG1690	Belongs to the RtcB family
ABC1921	COG2153	protein acetylation
ABC1924	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ABC1926	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ABC1927	COG2226	methyltransferase
ABC1928	COG1388	LysM domain
ABC1928	COG3584	3D domain protein
ABC1929	COG3584	3D domain protein
ABC1929	COG3583	domain protein
ABC1930	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ABC1931	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ABC1932	COG1011	Hydrolase
ABC1934	COG1122	ATPase activity
ABC1935	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ABC1936	COG2094	Belongs to the DNA glycosylase MPG family
ABC1938	COG0791	NLP P60 protein
ABC1938	COG1388	LysM domain
ABC1940	COG1309	transcriptional regulator
ABC1941	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABC1943	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABC1944	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABC1945	COG0626	cystathionine gamma-synthase activity
ABC1946	COG2329	Antibiotic biosynthesis monooxygenase
ABC1950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABC1952	COG1082	Xylose isomerase domain protein TIM barrel
ABC1953	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ABC1954	COG3048	D-serine ammonia-lyase activity
ABC1955	COG0708	Exodeoxyribonuclease III
ABC1956	COG0217	transcriptional regulatory protein
ABC1959	COG0697	spore germination
ABC1960	COG2151	metal-sulfur cluster biosynthetic enzyme
ABC1961	COG0733	neurotransmitter:sodium symporter activity
ABC1962	COG2207	Transcriptional regulator
ABC1962	COG3708	Transcriptional regulator
ABC1963	COG1695	Transcriptional regulator
ABC1965	COG2814	Major facilitator Superfamily
ABC1970	COG1131	(ABC) transporter
ABC1972	COG1595	DNA-templated transcription, initiation
ABC1974	COG0596	Alpha beta hydrolase
ABC1977	COG1413	lyase activity
ABC1979	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ABC1982	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABC1983	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ABC1984	COG1360	Flagellar Motor Protein
ABC1985	COG0628	permease
ABC1986	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ABC1988	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ABC1989	COG0187	DNA topoisomerase II activity
ABC1990	COG1832	CoA-binding protein
ABC1992	COG0517	IMP dehydrogenase activity
ABC1992	COG1125	glycine betaine transport
ABC1993	COG1028	Short-chain dehydrogenase reductase Sdr
ABC1995	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ABC2000	COG1070	Carbohydrate kinase
ABC2006	COG0840	transmembrane signaling receptor activity
ABC2006	COG3290	protein histidine kinase activity
ABC2008	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC2009	COG0028	Belongs to the TPP enzyme family
ABC2010	COG0673	inositol 2-dehydrogenase activity
ABC2011	COG0116	Belongs to the methyltransferase superfamily
ABC2014	COG0328	RNA-DNA hybrid ribonuclease activity
ABC2015	COG3599	regulation of cell shape
ABC2016	COG4474	Belongs to the UPF0398 family
ABC2018	COG3359	exonuclease
ABC2019	COG1111	helicase
ABC2019	COG1205	dead DEAH box helicase
ABC2021	COG0697	spore germination
ABC2022	COG0814	amino acid
ABC2025	COG0400	carboxylic ester hydrolase activity
ABC2026	COG0346	lactoylglutathione lyase activity
ABC2028	COG0561	phosphatase activity
ABC2034	COG0493	'glutamate synthase
ABC2035	COG0069	glutamate synthase activity
ABC2035	COG0070	glutamate synthase
ABC2035	COG0067	glutamate synthase
ABC2039	COG3428	Bacterial PH domain
ABC2040	COG3402	PFAM membrane-flanked domain
ABC2042	COG1413	lyase activity
ABC2047	COG1234	tRNA 3'-trailer cleavage
ABC2048	COG0693	protein deglycase activity
ABC2049	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABC2052	COG0789	Transcriptional regulator
ABC2054	COG3331	DNA recombination
ABC2055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABC2055	COG4499	WXG100 protein secretion system (Wss), protein YukC
ABC2056	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ABC2057	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABC2058	COG3935	DnaD domain protein
ABC2059	COG0017	Asparaginyl-tRNA synthetase
ABC2062	COG0402	S-adenosylhomocysteine deaminase activity
ABC2063	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABC2063	COG1199	ATP-dependent helicase activity
ABC2065	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ABC2066	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ABC2067	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ABC2069	COG0617	tRNA 3'-terminal CCA addition
ABC2070	COG0438	transferase activity, transferring glycosyl groups
ABC2075	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABC2075	COG2247	cell wall binding repeat
ABC2077	COG2188	Transcriptional regulator
ABC2078	COG1486	melibiose metabolic process
ABC2079	COG3394	polysaccharide catabolic process
ABC2080	COG1263	PTS System
ABC2080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC2086	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABC2087	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC2087	COG1263	PTS System
ABC2088	COG0561	phosphatase activity
ABC2091	COG0438	transferase activity, transferring glycosyl groups
ABC2098	COG3069	C4-dicarboxylate transmembrane transporter activity
ABC2099	COG1960	acyl-CoA dehydrogenase activity
ABC2101	COG4876	unkown
ABC2102	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABC2103	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ABC2104	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ABC2105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ABC2109	COG0514	ATP-dependent DNA helicase (RecQ)
ABC2110	COG0656	L-ascorbic acid biosynthetic process
ABC2111	COG0488	(ABC) transporter
ABC2113	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC2114	COG0567	Dehydrogenase, E1 component
ABC2116	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABC2118	COG1764	response to oxidative stress
ABC2119	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ABC2119	COG0551	DNA topoisomerase type I activity
ABC2121	COG1131	(ABC) transporter
ABC2124	COG4585	Histidine kinase
ABC2126	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABC2128	COG0720	synthase
ABC2129	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABC2130	COG2309	aminopeptidase activity
ABC2131	COG1115	amino acid carrier protein
ABC2132	COG1254	Belongs to the acylphosphatase family
ABC2134	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABC2136	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABC2140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABC2142	COG0784	Response regulator, receiver
ABC2142	COG0835	chemotaxis
ABC2147	COG2200	EAL domain
ABC2151	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ABC2152	COG0824	Thioesterase
ABC2153	COG0464	growth
ABC2157	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABC2160	COG1132	(ABC) transporter
ABC2161	COG1132	(ABC) transporter
ABC2162	COG3763	UPF0154 protein
ABC2164	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABC2165	COG4224	UPF0291 protein
ABC2166	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ABC2167	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ABC2168	COG2814	Major facilitator Superfamily
ABC2169	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ABC2172	COG1414	Transcriptional regulator
ABC2173	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABC2174	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ABC2175	COG0277	FAD linked oxidase domain protein
ABC2176	COG0247	lactate metabolic process
ABC2177	COG0277	FAD linked oxidase domain protein
ABC2179	COG0174	glutamine synthetase
ABC2180	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ABC2181	COG0464	growth
ABC2183	COG1923	regulation of RNA biosynthetic process
ABC2184	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ABC2186	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ABC2187	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABC2189	COG4550	Control of competence regulator ComK, YlbF/YmcA
ABC2190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABC2192	COG2359	stage V sporulation protein S
ABC2193	COG1692	metallophosphoesterase
ABC2194	COG1418	mRNA catabolic process
ABC2199	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABC2200	COG0513	Belongs to the DEAD box helicase family
ABC2201	COG1058	Belongs to the CinA family
ABC2201	COG1546	Belongs to the CinA family
ABC2202	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABC2203	COG1426	Protein conserved in bacteria
ABC2206	COG0300	oxidoreductase activity
ABC2207	COG0612	Peptidase, M16
ABC2208	COG0612	Peptidase, M16
ABC2209	COG2188	Transcriptional regulator
ABC2210	COG1674	ftsk spoiiie
ABC2212	COG0740	serine-type endopeptidase activity
ABC2213	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ABC2214	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC2215	COG0527	aspartate kinase activity
ABC2216	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ABC2217	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABC2218	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABC2220	COG0612	Peptidase, M16
ABC2221	COG0726	polysaccharide deacetylase
ABC2222	COG1185	polyribonucleotide nucleotidyltransferase activity
ABC2223	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ABC2224	COG0196	riboflavin kinase activity
ABC2225	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABC2226	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ABC2228	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABC2229	COG1358	cellular component organization or biogenesis
ABC2230	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ABC2231	COG0195	Participates in both transcription termination and antitermination
ABC2232	COG0779	Required for maturation of 30S ribosomal subunits
ABC2233	COG2176	DNA-directed DNA polymerase activity
ABC2234	COG0442	prolyl-tRNA aminoacylation
ABC2235	COG0750	zinc metalloprotease
ABC2236	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ABC2237	COG4589	Belongs to the CDS family
ABC2238	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABC2239	COG0233	cytoplasmic translational termination
ABC2240	COG0528	UMP kinase activity
ABC2241	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ABC2242	COG0052	Belongs to the universal ribosomal protein uS2 family
ABC2244	COG1191	sigma factor activity
ABC2245	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ABC2247	COG2201	protein-glutamate methylesterase activity
ABC2249	COG1419	protein localization to endoplasmic reticulum
ABC2250	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABC2251	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABC2252	COG1684	flagellar biosynthetic protein fliR
ABC2253	COG1987	bacterial-type flagellum assembly
ABC2254	COG1338	Plays a role in the flagellum-specific transport system
ABC2255	COG3190	flagellar
ABC2256	COG2201	protein-glutamate methylesterase activity
ABC2257	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABC2257	COG1776	CheC inhibitor of MCP methylation
ABC2258	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABC2261	COG4786	Flagellar basal body rod
ABC2262	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ABC2266	COG1157	protein secretion by the type III secretion system
ABC2267	COG1317	bacterial-type flagellum organization
ABC2268	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABC2269	COG1766	The M ring may be actively involved in energy transduction
ABC2270	COG1677	Flagellar hook-basal body complex protein FliE
ABC2271	COG1558	bacterial-type flagellum-dependent cell motility
ABC2272	COG1815	bacterial-type flagellum-dependent cell motility
ABC2273	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ABC2274	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ABC2275	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ABC2276	COG4974	Belongs to the 'phage' integrase family
ABC2277	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ABC2278	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ABC2279	COG0758	DNA mediated transformation
ABC2280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ABC2281	COG0045	succinate-CoA ligase (ADP-forming) activity
ABC2284	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABC2287	COG0335	large ribosomal subunit rRNA binding
ABC2288	COG0018	arginyl-trna synthetase
ABC2289	COG0336	Belongs to the RNA methyltransferase TrmD family
ABC2290	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABC2292	COG1837	Belongs to the UPF0109 family
ABC2293	COG0228	four-way junction DNA binding
ABC2294	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABC2295	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ABC2296	COG0552	protein localization to endoplasmic reticulum
ABC2297	COG1196	nuclear chromosome segregation
ABC2299	COG0571	ribonuclease III activity
ABC2300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABC2301	COG1028	Short-chain dehydrogenase reductase Sdr
ABC2302	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ABC2303	COG0416	fatty acid biosynthetic process
ABC2304	COG1349	DNA-binding transcription factor activity
ABC2305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ABC2306	COG1760	l-serine dehydratase
ABC2307	COG1760	l-serine dehydratase
ABC2308	COG1307	EDD domain protein, DegV family
ABC2309	COG1461	Dihydroxyacetone kinase
ABC2310	COG1302	Protein conserved in bacteria
ABC2311	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ABC2313	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABC2314	COG1162	GTPase activity
ABC2315	COG2815	serine threonine protein kinase
ABC2315	COG0515	serine threonine protein kinase
ABC2316	COG0631	protein serine/threonine phosphatase activity
ABC2317	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABC2317	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ABC2318	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABC2319	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABC2320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABC2321	COG1758	RNA polymerase activity
ABC2322	COG0194	GDP metabolic process
ABC2323	COG2052	Domain of unknown function (DUF370)
ABC2324	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABC2326	COG4485	Bacterial membrane protein, YfhO
ABC2329	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABC2330	COG0284	orotidine-5'-phosphate decarboxylase activity
ABC2331	COG0167	dihydroorotate dehydrogenase activity
ABC2332	COG0543	2 iron, 2 sulfur cluster binding
ABC2333	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABC2334	COG0505	Belongs to the CarA family
ABC2335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ABC2336	COG0540	Belongs to the ATCase OTCase family
ABC2337	COG2233	PERMEase
ABC2338	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ABC2339	COG0564	pseudouridine synthase activity
ABC2340	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ABC2341	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ABC2342	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABC2343	COG3599	regulation of cell shape
ABC2344	COG2302	S4 RNA-binding domain
ABC2345	COG0762	integral membrane protein
ABC2346	COG1799	cell septum assembly
ABC2347	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ABC2349	COG1873	PFAM PRC-barrel domain
ABC2350	COG1191	sigma factor activity
ABC2351	COG1191	sigma factor activity
ABC2353	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABC2354	COG0849	cell division
ABC2355	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ABC2356	COG0772	Belongs to the SEDS family
ABC2357	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ABC2358	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABC2359	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ABC2360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABC2361	COG0768	penicillin binding
ABC2362	COG0768	penicillin binding
ABC2363	COG4839	cell division protein FtsL
ABC2364	COG0275	rRNA processing
ABC2365	COG2001	Belongs to the MraZ family
ABC2366	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ABC2368	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ABC2369	COG0454	-acetyltransferase
ABC2371	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ABC2372	COG1399	metal-binding, possibly nucleic acid-binding protein
ABC2373	COG1323	Belongs to the UPF0348 family
ABC2374	COG3480	Lon protease (S16) C-terminal proteolytic domain
ABC2375	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABC2376	COG3314	Sporulation integral membrane protein YlbJ
ABC2377	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ABC2378	COG0742	ribosomal rna small subunit methyltransferase
ABC2380	COG4471	UPF0298 protein
ABC2386	COG2340	Cysteine-rich secretory protein family
ABC2389	COG2322	membrane
ABC2390	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABC2391	COG1845	cytochrome c oxidase, subunit III
ABC2392	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABC2393	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ABC2393	COG2010	Cytochrome c
ABC2394	COG1612	heme a metabolic process
ABC2395	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ABC2396	COG4838	Belongs to the UPF0358 family
ABC2397	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ABC2398	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ABC2399	COG4896	Protein conserved in bacteria
ABC2401	COG1217	gtp-binding protein TYPA
ABC2404	COG0483	inositol monophosphate 1-phosphatase activity
ABC2405	COG4493	Belongs to the UPF0637 family
ABC2407	COG1982	Orn Lys Arg decarboxylase major
ABC2410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABC2412	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC2413	COG0601	transmembrane transport
ABC2415	COG4608	Belongs to the ABC transporter superfamily
ABC2416	COG0444	Belongs to the ABC transporter superfamily
ABC2418	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC2419	COG0022	dehydrogenase e1 component
ABC2423	COG0242	peptide deformylase activity
ABC2424	COG5503	Protein of unknown function (DUF1447)
ABC2425	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ABC2426	COG0569	domain protein
ABC2427	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC2428	COG0450	alkyl hydroperoxide reductase
ABC2429	COG0668	transmembrane transport
ABC2431	COG1473	amidohydrolase
ABC2432	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC2433	COG2171	N-acyltransferase activity
ABC2436	COG0668	transmembrane transport
ABC2439	COG0702	epimerase
ABC2441	COG1902	pentaerythritol trinitrate reductase activity
ABC2443	COG2608	mercury ion transmembrane transporter activity
ABC2444	COG1937	Protein conserved in bacteria
ABC2446	COG0561	phosphatase activity
ABC2449	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC2450	COG0022	dehydrogenase e1 component
ABC2451	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ABC2452	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABC2454	COG3829	transcription factor binding
ABC2454	COG3290	protein histidine kinase activity
ABC2457	COG0745	RESPONSE REGULATOR receiver
ABC2458	COG0750	zinc metalloprotease
ABC2459	COG0497	DNA recombination
ABC2460	COG1438	arginine binding
ABC2461	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ABC2462	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ABC2463	COG0142	geranyltranstransferase activity
ABC2464	COG1722	exodeoxyribonuclease VII activity
ABC2465	COG1570	exodeoxyribonuclease VII activity
ABC2466	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABC2467	COG1302	Protein conserved in bacteria
ABC2468	COG0439	Biotin carboxylase
ABC2469	COG0511	ligase activity, forming carbon-carbon bonds
ABC2478	COG3854	ATPases associated with a variety of cellular activities
ABC2481	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ABC2482	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABC2483	COG0006	proline dipeptidase activity
ABC2486	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABC2487	COG1321	iron dependent repressor
ABC2488	COG1533	DNA photolyase activity
ABC2490	COG3973	AAA domain
ABC2491	COG0095	Lipoate-protein ligase
ABC2492	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABC2493	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABC2494	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABC2495	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ABC2496	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ABC2499	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABC2505	COG4537	Required for transformation and DNA binding
ABC2506	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ABC2508	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ABC2509	COG0210	DNA helicase
ABC2515	COG2226	methyltransferase
ABC2518	COG0564	pseudouridine synthase activity
ABC2519	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABC2520	COG2357	RelA SpoT domain protein
ABC2522	COG4116	CYTH
ABC2523	COG0741	lytic transglycosylase activity
ABC2524	COG2346	COG2346, Truncated hemoglobins
ABC2525	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ABC2527	COG4862	establishment of competence for transformation
ABC2528	COG1393	Belongs to the ArsC family
ABC2529	COG0456	acetyltransferase
ABC2532	COG1272	protein, Hemolysin III
ABC2533	COG1418	mRNA catabolic process
ABC2534	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC2535	COG0180	Tryptophanyl-tRNA synthetase
ABC2537	COG5504	Zn-dependent protease
ABC2538	COG2357	RelA SpoT domain protein
ABC2539	COG1072	(Pantothenic acid kinase))
ABC2540	COG2340	Cysteine-rich secretory protein family
ABC2541	COG3773	Cell wall hydrolase
ABC2541	COG3409	Peptidoglycan-binding domain 1 protein
ABC2543	COG0617	tRNA 3'-terminal CCA addition
ABC2546	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABC2547	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABC2549	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ABC2551	COG2267	carboxylic ester hydrolase activity
ABC2552	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABC2553	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABC2554	COG0505	Belongs to the CarA family
ABC2555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC2556	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABC2557	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ABC2558	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ABC2559	COG3336	cytochrome c oxidase
ABC2560	COG0561	phosphatase activity
ABC2564	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ABC2567	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABC2568	COG1073	alpha beta
ABC2570	COG0425	Belongs to the sulfur carrier protein TusA family
ABC2570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABC2572	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABC2573	COG1834	amidinotransferase
ABC2576	COG3209	COG3209 Rhs family protein
ABC2580	COG0367	asparagine synthase
ABC2581	COG0835	chemotaxis
ABC2582	COG0643	Histidine kinase
ABC2582	COG2198	Histidine kinase
ABC2587	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABC2588	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABC2589	COG0581	inorganic phosphate transmembrane transporter activity
ABC2590	COG0573	inorganic phosphate transmembrane transporter activity
ABC2591	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ABC2592	COG2318	DinB family
ABC2594	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ABC2595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC2596	COG1573	uracil-dna glycosylase
ABC2598	COG1228	amidohydrolase
ABC2599	COG2002	toxin-antitoxin pair type II binding
ABC2600	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ABC2601	COG2868	ribosomal protein
ABC2602	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABC2603	COG1530	ribonuclease E activity
ABC2604	COG1994	Peptidase M50
ABC2605	COG0739	heme binding
ABC2606	COG0667	Aldo Keto reductase
ABC2607	COG1268	BioY protein
ABC2608	COG0315	cyclic pyranopterin monophosphate synthase activity
ABC2609	COG0693	protein deglycase activity
ABC2610	COG2894	cell division
ABC2611	COG0850	regulation of cytokinetic process
ABC2612	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ABC2614	COG1077	Cell shape determining protein MreB Mrl
ABC2615	COG2003	Belongs to the UPF0758 family
ABC2616	COG0424	maF-like protein
ABC2617	COG0823	Involved in the tonB-independent uptake of proteins
ABC2617	COG1506	peptidase
ABC2617	COG4946	Tricorn protease homolog
ABC2619	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ABC2620	COG0285	dihydrofolate synthase activity
ABC2621	COG0525	valine-tRNA ligase activity
ABC2626	COG1388	LysM domain
ABC2626	COG1388	LysM domain
ABC2627	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABC2628	COG0113	porphobilinogen synthase activity
ABC2630	COG0181	hydroxymethylbilane synthase activity
ABC2631	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABC2632	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ABC2633	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ABC2634	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABC2635	COG0470	DNA polymerase III
ABC2635	COG1067	ATP-dependent peptidase activity
ABC2636	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ABC2637	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABC2638	COG0457	Tetratricopeptide repeat
ABC2638	COG1477	protein flavinylation
ABC2639	COG0066	3-isopropylmalate dehydratase activity
ABC2640	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABC2641	COG0473	3-isopropylmalate dehydrogenase activity
ABC2642	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABC2643	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABC2644	COG0440	acetolactate synthase activity
ABC2645	COG0028	Belongs to the TPP enzyme family
ABC2646	COG0129	dihydroxy-acid dehydratase activity
ABC2649	COG2132	Multicopper oxidase
ABC2650	COG0622	Phosphoesterase
ABC2651	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABC2652	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ABC2653	COG5401	PFAM Sporulation and spore germination
ABC2654	COG1054	Belongs to the UPF0176 family
ABC2656	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABC2657	COG1846	Transcriptional regulator
ABC2658	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ABC2659	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC2660	COG2197	response regulator
ABC2661	COG0824	Thioesterase
ABC2662	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABC2663	COG1053	succinate dehydrogenase
ABC2664	COG2009	succinate dehydrogenase
ABC2665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ABC2667	COG0322	excinuclease ABC activity
ABC2668	COG3118	belongs to the thioredoxin family
ABC2669	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ABC2670	COG2086	electron transfer activity
ABC2671	COG1024	Enoyl-CoA hydratase
ABC2672	COG1309	transcriptional regulator
ABC2673	COG0318	PFAM AMP-dependent synthetase and ligase
ABC2674	COG3766	membrane
ABC2675	COG1193	negative regulation of DNA recombination
ABC2676	COG1796	DNA polymerase
ABC2676	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ABC2677	COG1286	toxin biosynthetic process
ABC2678	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ABC2679	COG0072	phenylalanine-tRNA ligase activity
ABC2680	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ABC2681	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABC2683	COG1363	Peptidase, m42
ABC2685	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABC2686	COG3162	membrane
ABC2687	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ABC2688	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ABC2689	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABC2690	COG0577	efflux transmembrane transporter activity
ABC2691	COG1136	(ABC) transporter
ABC2694	COG2027	D-alanyl-D-alanine carboxypeptidase
ABC2697	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABC2699	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ABC2700	COG1484	DNA-dependent DNA replication
ABC2701	COG3611	Membrane attachment protein
ABC2702	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ABC2704	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ABC2705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABC2706	COG0237	dephospho-CoA kinase activity
ABC2707	COG1971	Probably functions as a manganese efflux pump
ABC2708	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ABC2709	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ABC2709	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ABC2710	COG5002	protein histidine kinase activity
ABC2711	COG0745	RESPONSE REGULATOR receiver
ABC2712	COG1522	sequence-specific DNA binding
ABC2713	COG0039	L-malate dehydrogenase activity
ABC2714	COG0538	isocitrate dehydrogenase activity
ABC2715	COG0372	Belongs to the citrate synthase family
ABC2716	COG2707	UPF0756 membrane protein
ABC2717	COG3030	protein affecting phage T7 exclusion by the F plasmid
ABC2719	COG0205	6-phosphofructokinase activity
ABC2720	COG0825	malonyl-CoA metabolic process
ABC2721	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ABC2722	COG2186	Transcriptional regulator
ABC2723	COG0281	malic enzyme
ABC2724	COG0587	DNA-directed DNA polymerase activity
ABC2727	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ABC2729	COG4109	DRTGG domain
ABC2731	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ABC2732	COG0006	proline dipeptidase activity
ABC2734	COG1028	Short-chain dehydrogenase reductase Sdr
ABC2736	COG0165	Argininosuccinate lyase
ABC2737	COG0137	argininosuccinate synthase activity
ABC2739	COG3481	metal-dependent phosphohydrolase, HD sub domain
ABC2740	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABC2741	COG0827	DNA restriction-modification system
ABC2742	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ABC2743	COG2814	Major facilitator Superfamily
ABC2744	COG3874	Sporulation protein YtfJ
ABC2746	COG1714	RDD family
ABC2747	COG0616	signal peptide processing
ABC2749	COG0301	tRNA thio-modification
ABC2750	COG1104	cysteine desulfurase activity
ABC2751	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ABC2752	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ABC2753	COG1309	transcriptional regulator
ABC2756	COG1956	GAF domain-containing protein
ABC2757	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABC2758	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ABC2759	COG4499	WXG100 protein secretion system (Wss), protein YukC
ABC2759	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABC2760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC2761	COG0454	-acetyltransferase
ABC2762	COG0517	IMP dehydrogenase activity
ABC2763	COG0123	including yeast histone deacetylase and acetoin utilization protein
ABC2765	COG1605	Chorismate mutase
ABC2765	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ABC2766	COG4980	gas vesicle protein
ABC2767	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ABC2768	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABC2769	COG1674	ftsk spoiiie
ABC2770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC2771	COG4848	Belongs to the UPF0354 family
ABC2772	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC2775	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ABC2776	COG1363	Peptidase, m42
ABC2778	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABC2780	COG0510	thiamine kinase activity
ABC2781	COG0788	formyltetrahydrofolate deformylase activity
ABC2784	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC2785	COG0022	dehydrogenase e1 component
ABC2786	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ABC2789	COG1346	cytolysis
ABC2790	COG1380	Effector of murein hydrolase LrgA
ABC2792	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABC2793	COG2207	Transcriptional regulator
ABC2793	COG3708	Transcriptional regulator
ABC2794	COG0789	Transcriptional regulator
ABC2795	COG0300	oxidoreductase activity
ABC2796	COG0346	lactoylglutathione lyase activity
ABC2797	COG1349	DNA-binding transcription factor activity
ABC2798	COG1187	pseudouridine synthase activity
ABC2799	COG0772	Belongs to the SEDS family
ABC2800	COG0772	Belongs to the SEDS family
ABC2801	COG2244	polysaccharide biosynthetic process
ABC2802	COG3386	PFAM SMP-30 Gluconolaconase
ABC2803	COG0432	Pfam Uncharacterised protein family UPF0047
ABC2804	COG1473	amidohydrolase
ABC2809	COG1793	dna ligase
ABC2822	COG5434	Belongs to the glycosyl hydrolase 28 family
ABC2824	COG5280	Phage tail tape measure protein TP901
ABC2824	COG3953	SLT domain
ABC2846	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ABC2847	COG0756	dUTP diphosphatase activity
ABC2855	COG3561	AntA/AntB antirepressor
ABC2864	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ABC2866	COG2081	HI0933 family
ABC2871	COG0495	leucyl-tRNA aminoacylation
ABC2872	COG0039	L-malate dehydrogenase activity
ABC2873	COG2814	Major facilitator Superfamily
ABC2874	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ABC2875	COG0288	reversible hydration of carbon dioxide
ABC2876	COG2267	carboxylic ester hydrolase activity
ABC2877	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ABC2878	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABC2879	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ABC2880	COG1506	peptidase
ABC2881	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABC2882	COG1116	anion transmembrane transporter activity
ABC2883	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC2884	COG0494	nUDIX hydrolase
ABC2885	COG2814	Major facilitator Superfamily
ABC2888	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ABC2889	COG1428	Deoxynucleoside kinase
ABC2890	COG1428	Deoxynucleoside kinase
ABC2893	COG4604	ABC transporter, ATP-binding protein
ABC2894	COG4605	iron ion homeostasis
ABC2895	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC2896	COG0671	phosphoesterase, PA-phosphatase related
ABC2897	COG1823	symporter activity
ABC2901	COG4846	Membrane protein involved in cytochrome C biogenesis
ABC2902	COG0109	protoheme IX farnesyltransferase activity
ABC2903	COG1227	inorganic diphosphatase activity
ABC2906	COG0166	Belongs to the GPI family
ABC2907	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABC2908	COG1979	alcohol dehydrogenase
ABC2909	COG2155	Conserved Protein
ABC2910	COG1098	S1 RNA binding domain
ABC2912	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ABC2913	COG0436	Aminotransferase
ABC2914	COG1522	sequence-specific DNA binding
ABC2915	COG1854	S-ribosylhomocysteine lyase activity
ABC2916	COG1295	ribonuclease BN
ABC2917	COG0776	regulation of translation
ABC2918	COG2056	Na+-H+ antiporter family
ABC2920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ABC2921	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ABC2922	COG3584	3D domain protein
ABC2924	COG1252	NADH dehydrogenase
ABC2925	COG0492	ferredoxin-NADP+ reductase activity
ABC2926	COG0246	Mannitol dehydrogenase
ABC2927	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC2928	COG3711	transcriptional antiterminator
ABC2930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC2931	COG0765	amino acid transport
ABC2932	COG0316	Belongs to the HesB IscA family
ABC2933	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ABC2934	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ABC2936	COG4844	belongs to the
ABC2937	COG1252	NADH dehydrogenase
ABC2938	COG4837	Protein of unknown function (DUF1462)
ABC2939	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ABC2940	COG0083	homoserine kinase activity
ABC2941	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ABC2942	COG0460	homoserine dehydrogenase
ABC2943	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ABC2944	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABC2945	COG0647	UMP catabolic process
ABC2946	COG2445	Protein of unknown function DUF86
ABC2948	COG4470	Protein conserved in bacteria
ABC2950	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABC2951	COG0739	heme binding
ABC2952	COG1757	Na H antiporter
ABC2955	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ABC2956	COG3377	Domain of unknown function (DUF1805)
ABC2957	COG0737	Belongs to the 5'-nucleotidase family
ABC2958	COG0730	response to heat
ABC2959	COG1801	Protein of unknown function DUF72
ABC2967	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ABC2968	COG2207	Transcriptional regulator
ABC2968	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABC2969	COG0667	Aldo Keto reductase
ABC2970	COG2226	methyltransferase
ABC2971	COG2723	6-phospho-beta-galactosidase activity
ABC2972	COG3711	transcriptional antiterminator
ABC2973	COG2224	Isocitrate lyase
ABC2974	COG0719	Fe-S assembly protein
ABC2975	COG0822	iron-sulfur transferase activity
ABC2976	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ABC2977	COG0719	Fe-S assembly protein
ABC2978	COG0396	ATPase activity
ABC2980	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC2981	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABC2983	COG1464	Belongs to the NlpA lipoprotein family
ABC2984	COG2011	ABC-type metal ion transport system permease component
ABC2985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABC2986	COG0509	glycine decarboxylation via glycine cleavage system
ABC2987	COG1393	Belongs to the ArsC family
ABC2988	COG1960	acyl-CoA dehydrogenase activity
ABC2989	COG0183	Belongs to the thiolase family
ABC2990	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC2990	COG1024	Enoyl-CoA hydratase
ABC2992	COG4533	DNA binding
ABC2996	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ABC2997	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABC2998	COG3314	Sporulation integral membrane protein YlbJ
ABC3002	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ABC3003	COG2259	Doxx family
ABC3004	COG0557	exoribonuclease II activity
ABC3005	COG1647	Serine aminopeptidase, S33
ABC3007	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABC3008	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABC3013	COG4948	Mandelate Racemase Muconate Lactonizing
ABC3014	COG1012	belongs to the aldehyde dehydrogenase family
ABC3015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC3016	COG1802	Transcriptional regulator
ABC3017	COG0148	phosphopyruvate hydratase activity
ABC3018	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ABC3019	COG0149	triose-phosphate isomerase activity
ABC3020	COG0126	phosphoglycerate kinase activity
ABC3025	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ABC3026	COG0740	serine-type endopeptidase activity
ABC3027	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC3029	COG1125	glycine betaine transport
ABC3029	COG0517	IMP dehydrogenase activity
ABC3030	COG1174	glycine betaine transport
ABC3031	COG1732	Glycine betaine
ABC3032	COG1174	glycine betaine transport
ABC3033	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC3034	COG1481	regulation of sporulation
ABC3035	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ABC3036	COG1660	Displays ATPase and GTPase activities
ABC3037	COG1051	belongs to the nudix hydrolase family
ABC3038	COG0492	ferredoxin-NADP+ reductase activity
ABC3040	COG2124	cytochrome p450
ABC3043	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABC3043	COG0140	phosphoribosyl-ATP diphosphatase activity
ABC3044	COG0107	imidazoleglycerol-phosphate synthase activity
ABC3045	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ABC3046	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABC3047	COG0131	Imidazoleglycerol-phosphate dehydratase
ABC3048	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABC3049	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ABC3050	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ABC3051	COG0110	maltose O-acetyltransferase activity
ABC3052	COG0546	phosphoglycolate phosphatase activity
ABC3053	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ABC3054	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ABC3055	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ABC3056	COG1950	PFAM Membrane protein of
ABC3057	COG3595	metallopeptidase activity
ABC3058	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ABC3059	COG0556	nucleotide-excision repair
ABC3062	COG0793	Belongs to the peptidase S41A family
ABC3062	COG3409	Peptidoglycan-binding domain 1 protein
ABC3063	COG0739	heme binding
ABC3064	COG2177	Part of the ABC transporter FtsEX involved in
ABC3065	COG2884	Cell division ATP-binding protein ftsE
ABC3066	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABC3067	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ABC3068	COG0653	protein targeting
ABC3069	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ABC3070	COG1278	Cold shock
ABC3073	COG1516	flagellar protein fliS
ABC3074	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ABC3075	COG1334	flagellar protein FlaG
ABC3076	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ABC3077	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ABC3078	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABC3079	COG1256	bacterial-type flagellum assembly
ABC3079	COG4786	Flagellar basal body rod
ABC3081	COG2747	anti-sigma28 factor FlgM
ABC3084	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ABC3085	COG1307	EDD domain protein, DegV family
ABC3088	COG1739	Uncharacterized protein family UPF0029
ABC3089	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ABC3090	COG4166	transmembrane transport
ABC3092	COG0601	transmembrane transport
ABC3093	COG4608	Belongs to the ABC transporter superfamily
ABC3096	COG1316	TRANSCRIPTIONal
ABC3097	COG4193	domain, Protein
ABC3098	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABC3099	COG1215	transferase activity, transferring glycosyl groups
ABC3099	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ABC3100	COG0463	Glycosyl transferase, family 2
ABC3100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ABC3101	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ABC3103	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ABC3104	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABC3105	COG1215	transferase activity, transferring glycosyl groups
ABC3107	COG1780	Probably involved in ribonucleotide reductase function
ABC3108	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABC3109	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABC3110	COG4112	unkown
ABC3111	COG1335	isochorismatase
ABC3113	COG3858	chitin binding
ABC3113	COG1388	LysM domain
ABC3114	COG1028	Short-chain dehydrogenase reductase Sdr
ABC3116	COG1621	beta-fructofuranosidase activity
ABC3118	COG0395	ABC-type sugar transport system, permease component
ABC3119	COG4209	transmembrane transport
ABC3120	COG1609	Transcriptional regulator
ABC3122	COG3842	ATPase activity
ABC3123	COG0395	ABC-type sugar transport system, permease component
ABC3124	COG1175	transmembrane transport
ABC3126	COG1472	Belongs to the glycosyl hydrolase 3 family
ABC3127	COG1396	sequence-specific DNA binding
ABC3132	COG1725	Transcriptional regulator
ABC3133	COG1131	(ABC) transporter
ABC3136	COG0800	Aldolase
ABC3138	COG1959	2 iron, 2 sulfur cluster binding
ABC3139	COG2112	serine threonine protein kinase
ABC3141	COG2203	Gaf domain
ABC3141	COG4585	Histidine kinase
ABC3142	COG2197	response regulator
ABC3144	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABC3145	COG1028	Short-chain dehydrogenase reductase Sdr
ABC3147	COG2378	regulation of single-species biofilm formation
ABC3148	COG2318	DinB family
ABC3149	COG0561	phosphatase activity
ABC3150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABC3151	COG0673	inositol 2-dehydrogenase activity
ABC3152	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ABC3153	COG2169	Transcriptional regulator
ABC3154	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABC3164	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABC3165	COG1215	transferase activity, transferring glycosyl groups
ABC3167	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ABC3170	COG0438	transferase activity, transferring glycosyl groups
ABC3179	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ABC3180	COG1473	amidohydrolase
ABC3185	COG1131	(ABC) transporter
ABC3186	COG0842	Transport permease protein
ABC3187	COG1309	transcriptional regulator
ABC3188	COG0655	NAD(P)H dehydrogenase (quinone) activity
ABC3189	COG0583	DNA-binding transcription factor activity
ABC3193	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABC3196	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC3196	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC3196	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC3197	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC3197	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC3197	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC3198	COG1105	Belongs to the carbohydrate kinase PfkB family
ABC3200	COG0589	response to stress
ABC3207	COG1177	transmembrane transport
ABC3208	COG3842	ATPase activity
ABC3209	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ABC3213	COG0395	ABC-type sugar transport system, permease component
ABC3216	COG0516	GMP reductase activity
ABC3217	COG1368	sulfuric ester hydrolase activity
ABC3219	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ABC3220	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ABC3221	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ABC3223	COG2814	Major facilitator Superfamily
ABC3224	COG4187	Peptidase family M20/M25/M40
ABC3225	COG1940	carbohydrate kinase activity
ABC3227	COG0745	RESPONSE REGULATOR receiver
ABC3228	COG5002	protein histidine kinase activity
ABC3229	COG1136	(ABC) transporter
ABC3230	COG0577	efflux transmembrane transporter activity
ABC3231	COG2217	Heavy metal translocating P-type atpase
ABC3235	COG3732	PTS system glucitol sorbitol-specific
ABC3236	COG3730	PTS system glucitol sorbitol-specific
ABC3239	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC3242	COG1846	Transcriptional regulator
ABC3243	COG0456	acetyltransferase
ABC3246	COG1116	anion transmembrane transporter activity
ABC3247	COG0247	lactate metabolic process
ABC3248	COG0277	FAD linked oxidase domain protein
ABC3249	COG3835	regulator
ABC3250	COG2270	Major facilitator Superfamily
ABC3251	COG1968	undecaprenyl-diphosphatase activity
ABC3253	COG1482	cell wall glycoprotein biosynthetic process
ABC3255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC3260	COG1177	transmembrane transport
ABC3261	COG1840	ABC-type Fe3 transport system, periplasmic component
ABC3262	COG3842	ATPase activity
ABC3263	COG0583	DNA-binding transcription factor activity
ABC3266	COG1309	transcriptional regulator
ABC3268	COG3420	alginic acid biosynthetic process
ABC3270	COG3328	transposase activity
ABC3272	COG0395	ABC-type sugar transport system, permease component
ABC3274	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ABC3276	COG0673	inositol 2-dehydrogenase activity
ABC3278	COG3708	Transcriptional regulator
ABC3278	COG2207	Transcriptional regulator
ABC3280	COG0395	ABC-type sugar transport system, permease component
ABC3281	COG1175	transmembrane transport
ABC3282	COG1653	transport
ABC3283	COG0673	inositol 2-dehydrogenase activity
ABC3285	COG1917	Cupin 2, conserved barrel domain protein
ABC3285	COG2207	Transcriptional regulator
ABC3286	COG0673	inositol 2-dehydrogenase activity
ABC3288	COG0384	phenazine biosynthesis protein PhzF
ABC3293	COG1368	sulfuric ester hydrolase activity
ABC3295	COG2247	cell wall binding repeat
ABC3295	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABC3296	COG5504	Zn-dependent protease
ABC3297	COG0501	Belongs to the peptidase M48B family
ABC3299	COG0395	ABC-type sugar transport system, permease component
ABC3301	COG1653	transport
ABC3305	COG0456	acetyltransferase
ABC3308	COG2261	transglycosylase associated protein
ABC3310	COG0124	histidyl-tRNA synthetase
ABC3311	COG1418	mRNA catabolic process
ABC3321	COG1078	dGTPase activity
ABC3323	COG0457	Tetratricopeptide repeat
ABC3326	COG3314	Sporulation integral membrane protein YlbJ
ABC3327	COG0402	S-adenosylhomocysteine deaminase activity
ABC3329	COG1228	amidohydrolase
ABC3330	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ABC3333	COG4585	Histidine kinase
ABC3334	COG2197	response regulator
ABC3336	COG3711	transcriptional antiterminator
ABC3337	COG1263	PTS System
ABC3337	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC3338	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABC3339	COG1388	LysM domain
ABC3341	COG0488	(ABC) transporter
ABC3342	COG1063	alcohol dehydrogenase
ABC3344	COG1063	alcohol dehydrogenase
ABC3345	COG3775	system Galactitol-specific IIC component
ABC3346	COG3414	Phosphotransferase system galactitol-specific IIB component
ABC3349	COG2217	Heavy metal translocating P-type atpase
ABC3351	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ABC3353	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ABC3354	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ABC3355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC3357	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC3358	COG1609	Transcriptional regulator
ABC3364	COG1694	Mazg nucleotide pyrophosphohydrolase
ABC3365	COG1134	teichoic acid transport
ABC3366	COG1682	transport, permease protein
ABC3368	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABC3369	COG3507	Belongs to the glycosyl hydrolase 43 family
ABC3371	COG3534	alpha-L-arabinofuranosidase
ABC3372	COG0725	ABC transporter, periplasmic molybdate-binding protein
ABC3373	COG4149	molybdate abc transporter
ABC3374	COG2197	response regulator
ABC3375	COG4585	Histidine kinase
ABC3382	COG1609	Transcriptional regulator
ABC3383	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ABC3385	COG1028	Short-chain dehydrogenase reductase Sdr
ABC3387	COG2032	superoxide dismutase activity
ABC3388	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABC3390	COG0640	Transcriptional regulator
ABC3391	COG0583	DNA-binding transcription factor activity
ABC3392	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABC3393	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC3394	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABC3395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABC3396	COG1116	anion transmembrane transporter activity
ABC3398	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABC3399	COG0431	NADPH-dependent FMN reductase
ABC3400	COG0583	DNA-binding transcription factor activity
ABC3402	COG2323	membrane
ABC3405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABC3406	COG1309	transcriptional regulator
ABC3408	COG1131	(ABC) transporter
ABC3411	COG1587	Uroporphyrinogen-III synthase
ABC3413	COG1063	alcohol dehydrogenase
ABC3414	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABC3415	COG3546	catalase activity
ABC3417	COG2113	Glycine betaine
ABC3418	COG1253	flavin adenine dinucleotide binding
ABC3419	COG4509	Sortase family
ABC3420	COG1120	ATPase activity
ABC3423	COG5386	Cell surface protein
ABC3424	COG5386	Cell surface protein
ABC3425	COG2329	Antibiotic biosynthesis monooxygenase
ABC3428	COG1063	alcohol dehydrogenase
ABC3429	COG2226	methyltransferase
ABC3430	COG1309	transcriptional regulator
ABC3431	COG0477	Major facilitator Superfamily
ABC3434	COG1028	Short-chain dehydrogenase reductase Sdr
ABC3436	COG0596	Alpha beta hydrolase
ABC3438	COG0673	inositol 2-dehydrogenase activity
ABC3439	COG0673	inositol 2-dehydrogenase activity
ABC3440	COG0395	ABC-type sugar transport system, permease component
ABC3441	COG1175	transmembrane transport
ABC3443	COG1940	carbohydrate kinase activity
ABC3444	COG2311	Membrane
ABC3448	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABC3449	COG0542	response to heat
ABC3455	COG2135	peptidase activity
ABC3456	COG2720	vancomycin resistance protein
ABC3461	COG1366	Belongs to the anti-sigma-factor antagonist family
ABC3466	COG2197	response regulator
ABC3468	COG1082	Xylose isomerase domain protein TIM barrel
ABC3469	COG0395	ABC-type sugar transport system, permease component
ABC3472	COG0673	inositol 2-dehydrogenase activity
ABC3473	COG1609	Transcriptional regulator
ABC3475	COG2207	Transcriptional regulator
ABC3476	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABC3478	COG1609	Transcriptional regulator
ABC3479	COG0840	transmembrane signaling receptor activity
ABC3481	COG2602	Beta-lactamase
ABC3484	COG2819	hydrolase of the alpha beta superfamily
ABC3485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC3486	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC3487	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABC3488	COG2207	Transcriptional regulator
ABC3488	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABC3491	COG0697	spore germination
ABC3492	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ABC3494	COG0577	efflux transmembrane transporter activity
ABC3495	COG1136	(ABC) transporter
ABC3496	COG1653	transport
ABC3497	COG1175	transmembrane transport
ABC3498	COG0395	ABC-type sugar transport system, permease component
ABC3501	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC3506	COG0693	protein deglycase activity
ABC3510	COG0789	Transcriptional regulator
ABC3511	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABC3512	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC3516	COG1874	Beta-galactosidase
ABC3518	COG3833	ABC-type maltose transport systems, permease component
ABC3519	COG1175	transmembrane transport
ABC3520	COG2182	Extracellular solute-binding protein
ABC3521	COG1609	Transcriptional regulator
ABC3525	COG0697	spore germination
ABC3526	COG1378	Sugar-specific transcriptional regulator TrmB
ABC3528	COG1131	(ABC) transporter
ABC3529	COG2207	Transcriptional regulator
ABC3532	COG1028	Short-chain dehydrogenase reductase Sdr
ABC3534	COG2312	Erythromycin esterase
ABC3535	COG1376	ErfK ybiS ycfS ynhG family protein
ABC3541	COG0300	oxidoreductase activity
ABC3544	COG1879	ABC-type sugar transport system periplasmic component
ABC3545	COG1172	Belongs to the binding-protein-dependent transport system permease family
ABC3546	COG1129	ABC transporter
ABC3547	COG1869	D-ribose catabolic process
ABC3548	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABC3549	COG1609	Transcriptional regulator
ABC3552	COG5002	protein histidine kinase activity
ABC3552	COG3850	Histidine kinase
ABC3553	COG0745	RESPONSE REGULATOR receiver
ABC3556	COG1131	(ABC) transporter
ABC3561	COG1132	(ABC) transporter
ABC3562	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ABC3563	COG1396	sequence-specific DNA binding
ABC3569	COG1063	alcohol dehydrogenase
ABC3570	COG3775	system Galactitol-specific IIC component
ABC3571	COG3414	Phosphotransferase system galactitol-specific IIB component
ABC3573	COG1349	DNA-binding transcription factor activity
ABC3579	COG1737	Transcriptional regulator
ABC3580	COG1263	PTS System
ABC3580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC3582	COG0445	tRNA wobble uridine modification
ABC3583	COG0395	ABC-type sugar transport system, permease component
ABC3584	COG1175	transmembrane transport
ABC3585	COG1653	transport
ABC3586	COG2972	Histidine kinase
ABC3587	COG2207	Transcriptional regulator
ABC3587	COG4753	response regulator
ABC3591	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ABC3592	COG1518	maintenance of DNA repeat elements
ABC3598	COG1794	racemase activity, acting on amino acids and derivatives
ABC3601	COG4682	membrane
ABC3602	COG1609	Transcriptional regulator
ABC3603	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABC3607	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC3608	COG1494	fructose-1,6-bisphosphatase
ABC3609	COG2376	Dihydroxyacetone kinase
ABC3610	COG2376	Dihydroxyacetone kinase
ABC3611	COG0698	ribose 5-phosphate isomerase
ABC3612	COG1349	DNA-binding transcription factor activity
ABC3613	COG1028	Short-chain dehydrogenase reductase Sdr
ABC3614	COG1063	alcohol dehydrogenase
ABC3615	COG2814	Major facilitator Superfamily
ABC3618	COG0318	PFAM AMP-dependent synthetase and ligase
ABC3620	COG1028	Short-chain dehydrogenase reductase Sdr
ABC3621	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC3621	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC3622	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC3623	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC3627	COG3546	catalase activity
ABC3630	COG0402	S-adenosylhomocysteine deaminase activity
ABC3631	COG1733	regulation of RNA biosynthetic process
ABC3632	COG1741	Belongs to the pirin family
ABC3640	COG1131	(ABC) transporter
ABC3641	COG0745	RESPONSE REGULATOR receiver
ABC3642	COG2205	protein histidine kinase activity
ABC3643	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABC3644	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ABC3646	COG4753	response regulator
ABC3646	COG2207	Transcriptional regulator
ABC3647	COG2972	Histidine kinase
ABC3649	COG3842	ATPase activity
ABC3650	COG1840	ABC-type Fe3 transport system, periplasmic component
ABC3653	COG1473	amidohydrolase
ABC3655	COG0471	metal ion transport
ABC3656	COG1473	amidohydrolase
ABC3657	COG4608	Belongs to the ABC transporter superfamily
ABC3658	COG0444	Belongs to the ABC transporter superfamily
ABC3659	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC3660	COG0601	transmembrane transport
ABC3661	COG0747	negative chemotaxis
ABC3662	COG0583	DNA-binding transcription factor activity
ABC3663	COG2971	BadF BadG BcrA BcrD
ABC3665	COG1447	Phosphotransferase system cellobiose-specific component IIA
ABC3666	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABC3666	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABC3669	COG1486	melibiose metabolic process
ABC3681	COG1733	regulation of RNA biosynthetic process
ABC3682	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABC3686	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ABC3687	COG2244	polysaccharide biosynthetic process
ABC3688	COG1091	dTDP-4-dehydrorhamnose reductase activity
ABC3691	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ABC3697	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABC3698	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABC3699	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABC3702	COG0814	amino acid
ABC3703	COG0697	spore germination
ABC3707	COG1028	Short-chain dehydrogenase reductase Sdr
ABC3708	COG1115	amino acid carrier protein
ABC3709	COG4122	O-methyltransferase activity
ABC3710	COG0583	DNA-binding transcription factor activity
ABC3711	COG0640	Transcriptional regulator
ABC3712	COG5658	integral membrane protein
ABC3716	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC3717	COG1116	anion transmembrane transporter activity
ABC3719	COG0693	protein deglycase activity
ABC3730	COG3361	conserved protein (COG2071)
ABC3731	COG0154	amidase activity
ABC3732	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ABC3733	COG1288	antiporter activity
ABC3735	COG3195	allantoin biosynthetic process
ABC3735	COG3648	Uricase
ABC3737	COG2508	Transcriptional regulator
ABC3738	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC3739	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABC3740	COG2080	2 iron, 2 sulfur cluster binding
ABC3741	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ABC3744	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ABC3746	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC3749	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC3750	COG1116	anion transmembrane transporter activity
ABC3753	COG0537	adenosine 5'-monophosphoramidase activity
ABC3754	COG1959	2 iron, 2 sulfur cluster binding
ABC3759	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABC3762	COG0300	oxidoreductase activity
ABC3764	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC3764	COG1263	PTS System
ABC3765	COG1621	beta-fructofuranosidase activity
ABC3766	COG1609	Transcriptional regulator
ABC3767	COG0778	Nitroreductase
ABC3770	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ABC3771	COG1914	H( )-stimulated, divalent metal cation uptake system
ABC3772	COG1984	allophanate hydrolase subunit 2
ABC3773	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ABC3775	COG1175	transmembrane transport
ABC3776	COG0395	ABC-type sugar transport system, permease component
ABC3786	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABC3788	COG2910	NAD(P)H-binding
ABC3789	COG1959	2 iron, 2 sulfur cluster binding
ABC3791	COG3711	transcriptional antiterminator
ABC3792	COG2723	6-phospho-beta-galactosidase activity
ABC3814	COG4464	protein tyrosine phosphatase activity
ABC3815	COG0489	protein tyrosine kinase activity
ABC3816	COG3944	biosynthesis protein
ABC3817	COG1316	TRANSCRIPTIONal
ABC3819	COG0590	tRNA wobble adenosine to inosine editing
ABC3820	COG0537	adenosine 5'-monophosphoramidase activity
ABC3821	COG0772	Belongs to the SEDS family
ABC3822	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABC3823	COG1316	TRANSCRIPTIONal
ABC3824	COG2388	GCN5-related N-acetyl-transferase
ABC3826	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ABC3827	COG0791	NLP P60 protein
ABC3827	COG1388	LysM domain
ABC3829	COG2318	DinB family
ABC3832	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ABC3834	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ABC3839	COG4786	Flagellar basal body rod
ABC3840	COG4786	Flagellar basal body rod
ABC3841	COG1077	Cell shape determining protein MreB Mrl
ABC3842	COG1609	Transcriptional regulator
ABC3843	COG2076	Multidrug Resistance protein
ABC3844	COG2076	Multidrug Resistance protein
ABC3845	COG0739	heme binding
ABC3846	COG2385	sporulation resulting in formation of a cellular spore
ABC3847	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABC3850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABC3851	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABC3852	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABC3853	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ABC3854	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABC3855	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABC3856	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABC3857	COG0356	it plays a direct role in the translocation of protons across the membrane
ABC3860	COG1404	Belongs to the peptidase S8 family
ABC3861	COG0456	acetyltransferase
ABC3862	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ABC3863	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABC3864	COG4475	Protein of unknown function (DUF436)
ABC3865	COG0698	ribose 5-phosphate isomerase
ABC3868	COG1971	Probably functions as a manganese efflux pump
ABC3870	COG0009	L-threonylcarbamoyladenylate synthase
ABC3874	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ABC3875	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABC3877	COG1435	thymidine kinase activity
ABC3878	COG0254	rRNA binding
ABC3879	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ABC3880	COG1494	fructose-1,6-bisphosphatase
ABC3881	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABC3882	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABC3883	COG0191	fructose-bisphosphate aldolase activity
ABC3886	COG0504	CTP synthase activity
ABC3887	COG3343	RNA polymerase activity
ABC3889	COG1960	acyl-CoA dehydrogenase activity
ABC3890	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC3891	COG0183	Belongs to the thiolase family
ABC3892	COG0247	lactate metabolic process
ABC3892	COG2181	nitrate reductase activity
ABC3893	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC3894	COG2839	Protein conserved in bacteria
ABC3895	COG0018	arginyl-trna synthetase
ABC3897	COG0010	Belongs to the arginase family
ABC3898	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ABC3899	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABC3901	COG1164	Oligoendopeptidase f
ABC3904	COG3764	Sortase (surface protein transpeptidase)
ABC3906	COG3465	dGTPase activity
ABC3907	COG1078	dGTPase activity
ABC3908	COG1301	dicarboxylic acid transport
ABC3909	COG0095	Lipoate-protein ligase
ABC3910	COG0280	phosphate acetyltransferase
ABC3911	COG1024	Enoyl-CoA hydratase
ABC3912	COG3253	May function as heme-dependent peroxidase
ABC3913	COG0706	membrane insertase activity
ABC3915	COG1668	transmembrane transport
ABC3916	COG4152	abc transporter atp-binding protein
ABC3917	COG1131	(ABC) transporter
ABC3918	COG2188	Transcriptional regulator
ABC3920	COG3773	Cell wall hydrolase
ABC3922	COG2363	Small membrane protein
ABC3923	COG0456	acetyltransferase
ABC3924	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABC3928	COG0004	ammonium transporteR
ABC3930	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ABC3931	COG3314	Sporulation integral membrane protein YlbJ
ABC3932	COG0351	phosphomethylpyrimidine kinase
ABC3933	COG2986	histidine ammonia-lyase
ABC3936	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC3943	COG0513	Belongs to the DEAD box helicase family
ABC3944	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC3945	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ABC3946	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC3946	COG0723	plastoquinol--plastocyanin reductase activity
ABC3949	COG2268	Band 7 protein
ABC3950	COG0024	Methionine aminopeptidase
ABC3952	COG1785	Belongs to the alkaline phosphatase family
ABC3953	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ABC3953	COG0551	DNA topoisomerase type I activity
ABC3954	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ABC3955	COG2814	Major facilitator Superfamily
ABC3958	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABC3959	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABC3959	COG1321	iron dependent repressor
ABC3960	COG1121	(ABC) transporter
ABC3961	COG0803	Belongs to the bacterial solute-binding protein 9 family
ABC3962	COG0561	phosphatase activity
ABC3963	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC3965	COG0840	transmembrane signaling receptor activity
ABC3966	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ABC3967	COG2814	Major facilitator Superfamily
ABC3969	COG0753	catalase activity
ABC3970	COG1132	(ABC) transporter
ABC3971	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ABC3972	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABC3973	COG2323	membrane
ABC3974	COG1597	lipid kinase activity
ABC3975	COG0789	Transcriptional regulator
ABC3976	COG5504	Zn-dependent protease
ABC3977	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ABC3978	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABC3979	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ABC3987	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABC3987	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABC3990	COG0745	RESPONSE REGULATOR receiver
ABC3990	COG2972	Histidine kinase
ABC3994	COG0471	metal ion transport
ABC3995	COG4565	transcriptional regulatory protein
ABC3996	COG3290	protein histidine kinase activity
ABC3997	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ABC4000	COG1114	Component of the transport system for branched-chain amino acids
ABC4005	COG0733	neurotransmitter:sodium symporter activity
ABC4006	COG2154	pterin-4-alpha-carbinolamine dehydratase
ABC4010	COG0745	RESPONSE REGULATOR receiver
ABC4012	COG2807	transmembrane transport
ABC4017	COG1307	EDD domain protein, DegV family
ABC4018	COG1193	negative regulation of DNA recombination
ABC4019	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ABC4020	COG0523	cobalamin synthesis protein
ABC4021	COG0813	purine-nucleoside phosphorylase activity
ABC4022	COG0346	lactoylglutathione lyase activity
ABC4024	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABC4025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ABC4026	COG2031	fatty acid transporter
ABC4027	COG1609	Transcriptional regulator
ABC4028	COG3833	ABC-type maltose transport systems, permease component
ABC4029	COG1175	transmembrane transport
ABC4030	COG2182	Extracellular solute-binding protein
ABC4032	COG0402	S-adenosylhomocysteine deaminase activity
ABC4033	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ABC4034	COG2508	Transcriptional regulator
ABC4035	COG0579	oxidoreductase
ABC4036	COG0247	lactate metabolic process
ABC4037	COG0277	FAD linked oxidase domain protein
ABC4038	COG2186	Transcriptional regulator
ABC4039	COG2186	Transcriptional regulator
ABC4042	COG0583	DNA-binding transcription factor activity
ABC4043	COG0372	Belongs to the citrate synthase family
ABC4046	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC4047	COG1802	Transcriptional regulator
ABC4048	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ABC4051	COG1595	DNA-templated transcription, initiation
ABC4056	COG1966	Carbon starvation protein
ABC4058	COG3275	phosphorelay sensor kinase activity
ABC4062	COG4608	Belongs to the ABC transporter superfamily
ABC4063	COG0444	Belongs to the ABC transporter superfamily
ABC4065	COG0601	transmembrane transport
ABC4069	COG1131	(ABC) transporter
ABC4073	COG3716	PTS system mannose fructose sorbose family IID component
ABC4075	COG3933	PFAM sigma-54 factor interaction domain-containing protein
ABC4075	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ABC4076	COG0235	Class ii aldolase
ABC4077	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC4077	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC4078	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC4079	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC4080	COG1063	alcohol dehydrogenase
ABC4085	COG2226	methyltransferase
ABC4086	COG0084	hydrolase, TatD family'
ABC4093	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ABC4094	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABC4095	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ABC4096	COG4853	Protein conserved in bacteria
ABC4098	COG5002	protein histidine kinase activity
ABC4099	COG0745	RESPONSE REGULATOR receiver
ABC4100	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ABC4101	COG0305	Participates in initiation and elongation during chromosome replication
ABC4102	COG0359	binds to the 23S rRNA
ABC4103	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ABC4105	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ABC4106	COG0629	single-stranded DNA binding
ABC4107	COG0360	Binds together with S18 to 16S ribosomal RNA
ABC4108	COG0012	GTP binding
ABC4109	COG3949	Membrane
ABC4111	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ABC4112	COG1475	DNA binding
ABC4113	COG1192	Involved in chromosome partitioning
ABC4114	COG1475	DNA binding
ABC4115	COG0357	Ribosomal RNA small subunit methyltransferase G
ABC4116	COG0445	tRNA wobble uridine modification
ABC4117	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABC4118	COG1847	R3H domain protein
ABC4119	COG0706	membrane insertase activity
ABC4120	COG0594	ribonuclease P activity
ABC4121	COG0230	Belongs to the bacterial ribosomal protein bL34 family