locus-tag	class	description
MM326_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MM326_00010	COG0592	DNA-directed DNA polymerase activity
MM326_00015	COG2501	S4 domain
MM326_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MM326_00030	COG0187	DNA topoisomerase II activity
MM326_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MM326_00045	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_00070	COG0516	GMP reductase activity
MM326_00070	COG0517	IMP dehydrogenase activity
MM326_00075	COG1686	Belongs to the peptidase S11 family
MM326_00085	COG2508	Transcriptional regulator
MM326_00090	COG0006	proline dipeptidase activity
MM326_00100	COG1473	amidohydrolase
MM326_00110	COG1012	belongs to the aldehyde dehydrogenase family
MM326_00115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM326_00120	COG0765	amino acid transport
MM326_00130	COG4608	Belongs to the ABC transporter superfamily
MM326_00135	COG0444	Belongs to the ABC transporter superfamily
MM326_00140	COG0601	transmembrane transport
MM326_00145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MM326_00150	COG0747	negative chemotaxis
MM326_00160	COG0590	tRNA wobble adenosine to inosine editing
MM326_00170	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MM326_00175	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MM326_00180	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MM326_00220	COG1982	Orn Lys Arg decarboxylase major
MM326_00225	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MM326_00230	COG3870	Protein conserved in bacteria
MM326_00235	COG0470	DNA polymerase III
MM326_00240	COG1774	PSP1 C-terminal conserved region
MM326_00245	COG4467	Involved in initiation control of chromosome replication
MM326_00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MM326_00255	COG2827	Endonuclease containing a URI domain
MM326_00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MM326_00265	COG2002	toxin-antitoxin pair type II binding
MM326_00280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MM326_00280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MM326_00285	COG0488	(ABC) transporter
MM326_00295	COG0084	hydrolase, TatD family'
MM326_00310	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MM326_00315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MM326_00325	COG4466	Protein conserved in bacteria
MM326_00335	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MM326_00340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MM326_00345	COG0251	oxidation-reduction process
MM326_00350	COG2088	sporulation resulting in formation of a cellular spore
MM326_00355	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MM326_00360	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MM326_00365	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MM326_00370	COG0193	aminoacyl-tRNA hydrolase activity
MM326_00380	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MM326_00385	COG2002	toxin-antitoxin pair type II binding
MM326_00395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MM326_00405	COG2244	polysaccharide biosynthetic process
MM326_00410	COG3956	TIGRFAM MazG family protein
MM326_00415	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MM326_00420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MM326_00425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MM326_00430	COG0492	ferredoxin-NADP+ reductase activity
MM326_00455	COG1098	S1 RNA binding domain
MM326_00465	COG2208	phosphoserine phosphatase activity
MM326_00470	COG2304	oxidoreductase activity
MM326_00475	COG0515	serine threonine protein kinase
MM326_00480	COG0037	tRNA processing
MM326_00485	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MM326_00490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MM326_00495	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MM326_00500	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MM326_00505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MM326_00510	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MM326_00515	COG0512	Glutamine amidotransferase of anthranilate synthase
MM326_00520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MM326_00525	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MM326_00530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MM326_00535	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MM326_00540	COG1396	sequence-specific DNA binding
MM326_00545	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MM326_00635	COG3880	PFAM UvrB UvrC protein
MM326_00640	COG3869	Catalyzes the specific phosphorylation of arginine residues in
MM326_00645	COG0542	response to heat
MM326_00650	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MM326_00655	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MM326_00660	COG4956	integral membrane protein (PIN domain superfamily)
MM326_00665	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MM326_00670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MM326_00675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MM326_00680	COG1045	serine acetyltransferase
MM326_00685	COG0215	cysteine-tRNA ligase activity
MM326_00695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MM326_00700	COG3688	RNA-binding protein containing a PIN domain
MM326_00715	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MM326_00720	COG0250	Participates in transcription elongation, termination and antitermination
MM326_00725	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MM326_00730	COG0081	regulation of translation
MM326_00735	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MM326_00740	COG0222	ribosome binding
MM326_00745	COG2813	Specifically methylates the guanine in position
MM326_00750	COG0085	RNA polymerase activity
MM326_00755	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MM326_00760	COG1358	cellular component organization or biogenesis
MM326_00765	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MM326_00770	COG0049	tRNA binding
MM326_00775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MM326_00780	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MM326_00790	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MM326_00795	COG0088	Forms part of the polypeptide exit tunnel
MM326_00800	COG0089	rRNA binding
MM326_00805	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MM326_00810	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MM326_00815	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MM326_00820	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MM326_00825	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MM326_00830	COG0255	Belongs to the universal ribosomal protein uL29 family
MM326_00835	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MM326_00840	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MM326_00845	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MM326_00850	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MM326_00855	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MM326_00860	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MM326_00865	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MM326_00870	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MM326_00875	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MM326_00880	COG1841	ribosomal large subunit assembly
MM326_00885	COG0200	Binds to the 23S rRNA
MM326_00890	COG0201	protein transport
MM326_00895	COG0563	adenylate kinase activity
MM326_00900	COG0024	Methionine aminopeptidase
MM326_00905	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MM326_00910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MM326_00915	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MM326_00920	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MM326_00925	COG0202	RNA polymerase activity
MM326_00930	COG0203	ribosomal protein L17
MM326_00935	COG1122	ATPase activity
MM326_00940	COG1122	ATPase activity
MM326_00950	COG0101	tRNA pseudouridine synthase activity
MM326_00955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MM326_00960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MM326_00965	COG2133	pyrroloquinoline quinone binding
MM326_00980	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM326_00985	COG3711	transcriptional antiterminator
MM326_00990	COG2190	(PTS) system
MM326_00990	COG1263	PTS System
MM326_00990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MM326_00995	COG0489	protein tyrosine kinase activity
MM326_01005	COG2194	sulfuric ester hydrolase activity
MM326_01010	COG0726	polysaccharide deacetylase
MM326_01065	COG2814	Major facilitator Superfamily
MM326_01085	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MM326_01145	COG1595	DNA-templated transcription, initiation
MM326_01150	COG5662	AntiSigma factor
MM326_01155	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MM326_01160	COG4856	YbbR-like protein
MM326_01165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MM326_01170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MM326_01185	COG1316	TRANSCRIPTIONal
MM326_01210	COG1280	lysine exporter protein (LysE YggA)
MM326_01235	COG2226	methyltransferase
MM326_01240	COG1349	DNA-binding transcription factor activity
MM326_01245	COG0110	maltose O-acetyltransferase activity
MM326_01250	COG1115	amino acid carrier protein
MM326_01265	COG1078	dGTPase activity
MM326_01270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MM326_01280	COG1012	belongs to the aldehyde dehydrogenase family
MM326_01285	COG0789	Transcriptional regulator
MM326_01295	COG0655	NAD(P)H dehydrogenase (quinone) activity
MM326_01335	COG2358	TRAP transporter, solute receptor (TAXI family
MM326_01340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MM326_01345	COG2267	carboxylic ester hydrolase activity
MM326_01350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MM326_01365	COG0628	permease
MM326_01370	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MM326_01370	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MM326_01385	COG0456	acetyltransferase
MM326_01395	COG0789	Transcriptional regulator
MM326_01400	COG1132	(ABC) transporter
MM326_01430	COG0640	Transcriptional regulator
MM326_01435	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MM326_01440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MM326_01450	COG1846	Transcriptional regulator
MM326_01465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MM326_01475	COG1396	sequence-specific DNA binding
MM326_01500	COG0640	Transcriptional regulator
MM326_01505	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MM326_01535	COG0640	Transcriptional regulator
MM326_01545	COG0604	alcohol dehydrogenase
MM326_01550	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_01555	COG3290	protein histidine kinase activity
MM326_01555	COG3829	transcription factor binding
MM326_01565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MM326_01570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MM326_01575	COG0427	acetyl-CoA hydrolase
MM326_01580	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MM326_01585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MM326_01585	COG1263	PTS System
MM326_01625	COG4841	protein insertion into membrane
MM326_01640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MM326_01645	COG1116	anion transmembrane transporter activity
MM326_01650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MM326_01655	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MM326_01660	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MM326_01665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MM326_01670	COG2080	2 iron, 2 sulfur cluster binding
MM326_01675	COG3195	allantoin biosynthetic process
MM326_01675	COG3648	Uricase
MM326_01680	COG3195	allantoin biosynthetic process
MM326_01680	COG3648	Uricase
MM326_01685	COG2351	hydroxyisourate hydrolase activity
MM326_01700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MM326_01705	COG1984	allophanate hydrolase subunit 2
MM326_01710	COG4336	lyase activity
MM326_01715	COG1914	H( )-stimulated, divalent metal cation uptake system
MM326_01720	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MM326_01725	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MM326_01745	COG2066	Belongs to the glutaminase family
MM326_01750	COG0556	nucleotide-excision repair
MM326_01765	COG1063	alcohol dehydrogenase
MM326_01775	COG3829	transcription factor binding
MM326_01775	COG3290	protein histidine kinase activity
MM326_01780	COG1454	alcohol dehydrogenase
MM326_01790	COG1012	belongs to the aldehyde dehydrogenase family
MM326_01795	COG0456	acetyltransferase
MM326_01810	COG2318	DinB family
MM326_01840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM326_01860	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MM326_01875	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_01885	COG3634	alkyl hydroperoxide reductase activity
MM326_01890	COG0450	alkyl hydroperoxide reductase
MM326_01920	COG0179	Fumarylacetoacetate (FAA) hydrolase
MM326_01925	COG0583	DNA-binding transcription factor activity
MM326_01935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MM326_01940	COG1012	belongs to the aldehyde dehydrogenase family
MM326_01965	COG0697	spore germination
MM326_01975	COG0456	acetyltransferase
MM326_01980	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MM326_01985	COG1917	Cupin 2, conserved barrel domain protein
MM326_01995	COG0584	glycerophosphoryl diester phosphodiesterase
MM326_02020	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_02025	COG0655	NAD(P)H dehydrogenase (quinone) activity
MM326_02030	COG1064	alcohol dehydrogenase
MM326_02045	COG0673	inositol 2-dehydrogenase activity
MM326_02050	COG1228	amidohydrolase
MM326_02055	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MM326_02065	COG0402	S-adenosylhomocysteine deaminase activity
MM326_02070	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
MM326_02075	COG0628	permease
MM326_02085	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MM326_02100	COG3655	Transcriptional regulator
MM326_02110	COG0604	alcohol dehydrogenase
MM326_02115	COG2226	methyltransferase
MM326_02130	COG1309	transcriptional regulator
MM326_02155	COG0586	Pfam SNARE associated Golgi protein
MM326_02170	COG0494	nUDIX hydrolase
MM326_02180	COG1366	Belongs to the anti-sigma-factor antagonist family
MM326_02185	COG1937	Protein conserved in bacteria
MM326_02190	COG2210	Belongs to the sulfur carrier protein TusA family
MM326_02195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MM326_02195	COG0425	Belongs to the sulfur carrier protein TusA family
MM326_02200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM326_02200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MM326_02205	COG0425	Belongs to the sulfur carrier protein TusA family
MM326_02205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MM326_02210	COG0730	response to heat
MM326_02215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MM326_02220	COG2011	ABC-type metal ion transport system permease component
MM326_02225	COG1464	Belongs to the NlpA lipoprotein family
MM326_02230	COG1473	amidohydrolase
MM326_02235	COG3285	dna ligase
MM326_02235	COG1793	dna ligase
MM326_02240	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MM326_02275	COG1823	symporter activity
MM326_02315	COG1250	3-hydroxyacyl-CoA dehydrogenase
MM326_02315	COG1024	Enoyl-CoA hydratase
MM326_02320	COG0473	3-isopropylmalate dehydrogenase activity
MM326_02355	COG2972	Histidine kinase
MM326_02360	COG2207	Transcriptional regulator
MM326_02360	COG4753	response regulator
MM326_02370	COG1175	transmembrane transport
MM326_02375	COG0395	ABC-type sugar transport system, permease component
MM326_02380	COG1609	Transcriptional regulator
MM326_02385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MM326_02390	COG1869	D-ribose catabolic process
MM326_02395	COG1129	ABC transporter
MM326_02400	COG1172	Belongs to the binding-protein-dependent transport system permease family
MM326_02405	COG1879	ABC-type sugar transport system periplasmic component
MM326_02425	COG2135	peptidase activity
MM326_02435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MM326_02440	COG0456	acetyltransferase
MM326_02465	COG0346	lactoylglutathione lyase activity
MM326_02475	COG1966	Carbon starvation protein
MM326_02480	COG0366	Alpha amylase catalytic
MM326_02485	COG2112	serine threonine protein kinase
MM326_02495	COG0471	metal ion transport
MM326_02500	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MM326_02530	COG2301	Belongs to the HpcH HpaI aldolase family
MM326_02535	COG0697	spore germination
MM326_02540	COG2207	Transcriptional regulator
MM326_02540	COG1917	Cupin 2, conserved barrel domain protein
MM326_02555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MM326_02560	COG0697	spore germination
MM326_02565	COG0531	amino acid
MM326_02590	COG2076	Multidrug Resistance protein
MM326_02595	COG2076	Multidrug Resistance protein
MM326_02600	COG0010	Belongs to the arginase family
MM326_02610	COG1115	amino acid carrier protein
MM326_02640	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM326_02650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM326_02660	COG0583	DNA-binding transcription factor activity
MM326_02665	COG2249	NAD(P)H dehydrogenase (quinone) activity
MM326_02725	COG2188	Transcriptional regulator
MM326_02730	COG1486	melibiose metabolic process
MM326_02735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MM326_02740	COG1447	Phosphotransferase system cellobiose-specific component IIA
MM326_02800	COG3409	Peptidoglycan-binding domain 1 protein
MM326_02800	COG5632	N-Acetylmuramoyl-L-alanine amidase
MM326_02815	COG1253	flavin adenine dinucleotide binding
MM326_02820	COG1253	flavin adenine dinucleotide binding
MM326_02845	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
MM326_02860	COG0483	inositol monophosphate 1-phosphatase activity
MM326_02875	COG3093	addiction module antidote protein HigA
MM326_02920	COG3588	fructose-bisphosphate aldolase
MM326_02930	COG0124	histidyl-tRNA synthetase
MM326_02955	COG3279	Response regulator of the LytR AlgR family
MM326_02960	COG1131	(ABC) transporter
MM326_02970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MM326_02975	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MM326_02980	COG0640	Transcriptional regulator
MM326_02985	COG0346	lactoylglutathione lyase activity
MM326_02990	COG0640	Transcriptional regulator
MM326_03010	COG1301	dicarboxylic acid transport
MM326_03020	COG0583	DNA-binding transcription factor activity
MM326_03035	COG1228	amidohydrolase
MM326_03045	COG2508	Transcriptional regulator
MM326_03050	COG4821	SIS domain
MM326_03070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM326_03070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM326_03085	COG1811	Na channel or pump
MM326_03100	COG3173	Aminoglycoside phosphotransferase
MM326_03105	COG0402	S-adenosylhomocysteine deaminase activity
MM326_03140	COG1982	Orn Lys Arg decarboxylase major
MM326_03145	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MM326_03160	COG1175	transmembrane transport
MM326_03165	COG0395	ABC-type sugar transport system, permease component
MM326_03180	COG2226	methyltransferase
MM326_03205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MM326_03230	COG3279	Response regulator of the LytR AlgR family
MM326_03260	COG2851	Citrate transporter
MM326_03270	COG0471	metal ion transport
MM326_03275	COG0561	phosphatase activity
MM326_03295	COG1131	(ABC) transporter
MM326_03310	COG1131	(ABC) transporter
MM326_03325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM326_03345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MM326_03360	COG1131	(ABC) transporter
MM326_03425	COG4335	DNA alkylation repair
MM326_03430	COG3239	Fatty acid desaturase
MM326_03435	COG4585	Histidine kinase
MM326_03440	COG2197	response regulator
MM326_03450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM326_03550	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MM326_03555	COG4208	sulfate ABC transporter
MM326_03565	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MM326_03575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM326_03580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MM326_03585	COG1960	acyl-CoA dehydrogenase activity
MM326_03605	COG1960	acyl-CoA dehydrogenase activity
MM326_03610	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MM326_03615	COG0318	PFAM AMP-dependent synthetase and ligase
MM326_03620	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_03630	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_03640	COG2030	dehydratase
MM326_03660	COG1309	transcriptional regulator
MM326_03665	COG2814	Major facilitator Superfamily
MM326_03675	COG0154	amidase activity
MM326_03710	COG0789	Transcriptional regulator
MM326_03730	COG1193	negative regulation of DNA recombination
MM326_03735	COG0446	pyridine nucleotide-disulphide oxidoreductase
MM326_03750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MM326_03790	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_03805	COG0456	acetyltransferase
MM326_03830	COG2378	regulation of single-species biofilm formation
MM326_03845	COG0346	lactoylglutathione lyase activity
MM326_03850	COG1959	2 iron, 2 sulfur cluster binding
MM326_03870	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MM326_03895	COG1012	belongs to the aldehyde dehydrogenase family
MM326_03915	COG1988	membrane-bound metal-dependent
MM326_03920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MM326_03925	COG0390	transport system, permease component
MM326_03930	COG0778	Nitroreductase
MM326_03960	COG4536	flavin adenine dinucleotide binding
MM326_03965	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MM326_03970	COG1074	ATP-dependent DNA helicase activity
MM326_03980	COG2807	transmembrane transport
MM326_03990	COG0494	nUDIX hydrolase
MM326_04005	COG1846	Transcriptional regulator
MM326_04010	COG2153	protein acetylation
MM326_04015	COG2814	Major facilitator Superfamily
MM326_04020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM326_04035	COG3584	3D domain protein
MM326_04035	COG1388	LysM domain
MM326_04050	COG1309	transcriptional regulator
MM326_04055	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_04060	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_04065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MM326_04070	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MM326_04080	COG1175	transmembrane transport
MM326_04085	COG0395	ABC-type sugar transport system, permease component
MM326_04090	COG5578	integral membrane protein
MM326_04100	COG0693	protein deglycase activity
MM326_04110	COG2971	BadF BadG BcrA BcrD
MM326_04115	COG0277	FAD linked oxidase domain protein
MM326_04120	COG0247	lactate metabolic process
MM326_04125	COG1737	Transcriptional regulator
MM326_04130	COG3876	Protein conserved in bacteria
MM326_04135	COG1472	Belongs to the glycosyl hydrolase 3 family
MM326_04140	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MM326_04145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MM326_04150	COG2188	Transcriptional regulator
MM326_04155	COG1131	(ABC) transporter
MM326_04175	COG0673	inositol 2-dehydrogenase activity
MM326_04180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MM326_04185	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MM326_04190	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MM326_04190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MM326_04200	COG1012	belongs to the aldehyde dehydrogenase family
MM326_04210	COG0028	Belongs to the TPP enzyme family
MM326_04215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MM326_04220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MM326_04230	COG2182	Extracellular solute-binding protein
MM326_04235	COG1175	transmembrane transport
MM326_04240	COG3833	ABC-type maltose transport systems, permease component
MM326_04245	COG0366	Alpha amylase catalytic
MM326_04250	COG1609	Transcriptional regulator
MM326_04255	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM326_04260	COG0395	ABC-type sugar transport system, permease component
MM326_04265	COG1175	transmembrane transport
MM326_04275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MM326_04280	COG0569	domain protein
MM326_04285	COG0673	inositol 2-dehydrogenase activity
MM326_04320	COG1302	Protein conserved in bacteria
MM326_04325	COG0175	sulfate reduction
MM326_04330	COG2046	Belongs to the sulfate adenylyltransferase family
MM326_04335	COG0529	Catalyzes the synthesis of activated sulfate
MM326_04340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MM326_04340	COG1587	Uroporphyrinogen-III synthase
MM326_04350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MM326_04350	COG1648	precorrin-2 dehydrogenase activity
MM326_04355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MM326_04360	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MM326_04380	COG1051	belongs to the nudix hydrolase family
MM326_04415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MM326_04420	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MM326_04425	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
MM326_04430	COG0492	ferredoxin-NADP+ reductase activity
MM326_04440	COG3396	Phenylacetate-CoA oxygenase
MM326_04465	COG1024	Enoyl-CoA hydratase
MM326_04470	COG1024	Enoyl-CoA hydratase
MM326_04475	COG1250	3-hydroxyacyl-CoA dehydrogenase
MM326_04480	COG0183	Belongs to the thiolase family
MM326_04485	COG3327	negative regulation of DNA-templated transcription, initiation
MM326_04490	COG2070	2-Nitropropane dioxygenase
MM326_04495	COG0659	secondary active sulfate transmembrane transporter activity
MM326_04500	COG0733	neurotransmitter:sodium symporter activity
MM326_04545	COG0406	alpha-ribazole phosphatase activity
MM326_04550	COG2333	competence protein COMEC
MM326_04550	COG0658	competence protein
MM326_04650	COG2323	membrane
MM326_04675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MM326_04700	COG0583	DNA-binding transcription factor activity
MM326_04705	COG2855	membrane
MM326_04725	COG4585	Histidine kinase
MM326_04730	COG2197	response regulator
MM326_04735	COG3142	Participates in the control of copper homeostasis
MM326_04745	COG1682	transport, permease protein
MM326_04750	COG1134	teichoic acid transport
MM326_04755	COG1363	Peptidase, m42
MM326_04775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM326_04785	COG3414	Phosphotransferase system galactitol-specific IIB component
MM326_04790	COG3775	system Galactitol-specific IIC component
MM326_04795	COG1063	alcohol dehydrogenase
MM326_04805	COG1063	alcohol dehydrogenase
MM326_04815	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_04820	COG0583	DNA-binding transcription factor activity
MM326_04825	COG0488	(ABC) transporter
MM326_04840	COG3448	diguanylate cyclase activity
MM326_04840	COG4175	Glycine betaine
MM326_04845	COG2050	protein possibly involved in aromatic compounds catabolism
MM326_04850	COG1619	proteins homologs of microcin C7 resistance protein MccF
MM326_04895	COG1366	Belongs to the anti-sigma-factor antagonist family
MM326_04895	COG2202	Pas domain
MM326_04905	COG1418	mRNA catabolic process
MM326_04920	COG0395	ABC-type sugar transport system, permease component
MM326_04930	COG0438	transferase activity, transferring glycosyl groups
MM326_04930	COG1216	Glycosyl transferase, family 2
MM326_04940	COG2814	Major facilitator Superfamily
MM326_04950	COG0500	methyltransferase
MM326_04970	COG0501	Belongs to the peptidase M48B family
MM326_04975	COG4989	oxidoreductase activity
MM326_04980	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM326_04980	COG2247	cell wall binding repeat
MM326_04985	COG1368	sulfuric ester hydrolase activity
MM326_04990	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MM326_05000	COG1309	transcriptional regulator
MM326_05025	COG0673	inositol 2-dehydrogenase activity
MM326_05030	COG2207	Transcriptional regulator
MM326_05030	COG1917	Cupin 2, conserved barrel domain protein
MM326_05040	COG0673	inositol 2-dehydrogenase activity
MM326_05045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MM326_05050	COG1482	cell wall glycoprotein biosynthetic process
MM326_05060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MM326_05095	COG1091	dTDP-4-dehydrorhamnose reductase activity
MM326_05110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM326_05160	COG1940	carbohydrate kinase activity
MM326_05165	COG4187	Peptidase family M20/M25/M40
MM326_05170	COG2814	Major facilitator Superfamily
MM326_05185	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MM326_05190	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MM326_05205	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MM326_05215	COG2252	PERMEase
MM326_05245	COG2217	Heavy metal translocating P-type atpase
MM326_05255	COG2217	Heavy metal translocating P-type atpase
MM326_05265	COG0506	proline dehydrogenase activity
MM326_05275	COG1012	belongs to the aldehyde dehydrogenase family
MM326_05290	COG0737	Belongs to the 5'-nucleotidase family
MM326_05295	COG1073	alpha beta
MM326_05300	COG0326	Molecular chaperone. Has ATPase activity
MM326_05305	COG2124	cytochrome p450
MM326_05310	COG1335	isochorismatase
MM326_05315	COG2031	fatty acid transporter
MM326_05320	COG1454	alcohol dehydrogenase
MM326_05325	COG1012	belongs to the aldehyde dehydrogenase family
MM326_05330	COG1510	regulation of RNA biosynthetic process
MM326_05340	COG1620	l-lactate permease
MM326_05345	COG0247	lactate metabolic process
MM326_05350	COG1139	Iron-sulfur cluster binding protein
MM326_05355	COG1556	Lactate utilization protein
MM326_05360	COG2186	Transcriptional regulator
MM326_05375	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MM326_05380	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
MM326_05385	COG2059	Chromate
MM326_05390	COG2059	Chromate
MM326_05400	COG0789	Transcriptional regulator
MM326_05415	COG1695	Transcriptional regulator
MM326_05420	COG3424	synthase
MM326_05425	COG1755	Isoprenylcysteine carboxyl methyltransferase
MM326_05430	COG3949	Membrane
MM326_05445	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MM326_05450	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MM326_05455	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MM326_05460	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MM326_05465	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MM326_05470	COG0047	phosphoribosylformylglycinamidine synthase activity
MM326_05475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MM326_05480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MM326_05485	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MM326_05490	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MM326_05495	COG0138	bifunctional purine biosynthesis protein purh
MM326_05500	COG0151	Belongs to the GarS family
MM326_05545	COG4585	Histidine kinase
MM326_05550	COG2197	response regulator
MM326_05555	COG1131	(ABC) transporter
MM326_05580	COG1510	regulation of RNA biosynthetic process
MM326_05600	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MM326_05605	COG2224	Isocitrate lyase
MM326_05620	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MM326_05625	COG4496	protein, YerC YecD
MM326_05630	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MM326_05645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MM326_05655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM326_05660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM326_05665	COG1120	ATPase activity
MM326_05675	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MM326_05680	COG0210	DNA helicase
MM326_05685	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MM326_05690	COG4851	CamS sex pheromone cAM373 precursor
MM326_05700	COG2318	DinB family
MM326_05705	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MM326_05715	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MM326_05720	COG0154	amidase activity
MM326_05725	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MM326_05730	COG1597	lipid kinase activity
MM326_05735	COG1349	DNA-binding transcription factor activity
MM326_05745	COG3414	Phosphotransferase system galactitol-specific IIB component
MM326_05765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MM326_05775	COG1960	acyl-CoA dehydrogenase activity
MM326_05785	COG0196	riboflavin kinase activity
MM326_05795	COG2267	carboxylic ester hydrolase activity
MM326_05825	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MM326_05830	COG0686	Belongs to the AlaDH PNT family
MM326_05835	COG2508	Transcriptional regulator
MM326_05835	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MM326_05840	COG1115	amino acid carrier protein
MM326_05845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MM326_05860	COG1070	Carbohydrate kinase
MM326_05870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MM326_05890	COG1012	belongs to the aldehyde dehydrogenase family
MM326_05920	COG1595	DNA-templated transcription, initiation
MM326_05925	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MM326_05955	COG0398	Pfam SNARE associated Golgi protein
MM326_05960	COG0456	acetyltransferase
MM326_05980	COG3181	Tripartite tricarboxylate transporter family receptor
MM326_05990	COG1414	Transcriptional regulator
MM326_05995	COG0710	3-dehydroquinate dehydratase activity
MM326_06000	COG1733	regulation of RNA biosynthetic process
MM326_06010	COG0431	NADPH-dependent FMN reductase
MM326_06015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MM326_06020	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MM326_06025	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MM326_06045	COG2814	Major facilitator Superfamily
MM326_06050	COG1378	Sugar-specific transcriptional regulator TrmB
MM326_06065	COG0659	secondary active sulfate transmembrane transporter activity
MM326_06075	COG1380	Effector of murein hydrolase LrgA
MM326_06080	COG1346	cytolysis
MM326_06090	COG1131	(ABC) transporter
MM326_06110	COG1078	dGTPase activity
MM326_06120	COG1752	Esterase of the alpha-beta hydrolase superfamily
MM326_06130	COG0583	DNA-binding transcription factor activity
MM326_06135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MM326_06150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM326_06155	COG1595	DNA-templated transcription, initiation
MM326_06175	COG1131	(ABC) transporter
MM326_06180	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MM326_06185	COG5002	protein histidine kinase activity
MM326_06195	COG2391	methyltransferase activity
MM326_06200	COG2113	Glycine betaine
MM326_06215	COG1597	lipid kinase activity
MM326_06230	COG0444	Belongs to the ABC transporter superfamily
MM326_06235	COG4608	Belongs to the ABC transporter superfamily
MM326_06240	COG0747	negative chemotaxis
MM326_06245	COG0601	transmembrane transport
MM326_06250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MM326_06270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MM326_06275	COG3973	AAA domain
MM326_06280	COG2755	lipolytic protein G-D-S-L family
MM326_06290	COG1132	(ABC) transporter
MM326_06295	COG1132	(ABC) transporter
MM326_06305	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_06310	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MM326_06315	COG1115	amino acid carrier protein
MM326_06320	COG2244	polysaccharide biosynthetic process
MM326_06330	COG1263	PTS System
MM326_06330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MM326_06335	COG2188	Transcriptional regulator
MM326_06340	COG0386	Belongs to the glutathione peroxidase family
MM326_06345	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MM326_06350	COG0488	(ABC) transporter
MM326_06355	COG1349	DNA-binding transcription factor activity
MM326_06360	COG1105	Belongs to the carbohydrate kinase PfkB family
MM326_06365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MM326_06365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM326_06365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MM326_06385	COG1077	Cell shape determining protein MreB Mrl
MM326_06390	COG3011	Protein conserved in bacteria
MM326_06405	COG0328	RNA-DNA hybrid ribonuclease activity
MM326_06405	COG3341	Caulimovirus viroplasmin
MM326_06410	COG1012	belongs to the aldehyde dehydrogenase family
MM326_06420	COG0753	catalase activity
MM326_06435	COG1164	Oligoendopeptidase f
MM326_06445	COG1294	oxidase, subunit
MM326_06450	COG1271	oxidase subunit
MM326_06475	COG0535	radical SAM domain protein
MM326_06485	COG0406	alpha-ribazole phosphatase activity
MM326_06490	COG1253	flavin adenine dinucleotide binding
MM326_06500	COG0726	polysaccharide deacetylase
MM326_06510	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MM326_06525	COG1619	proteins homologs of microcin C7 resistance protein MccF
MM326_06535	COG1090	epimerase
MM326_06540	COG2137	regulation of response to DNA damage stimulus
MM326_06560	COG1988	membrane-bound metal-dependent
MM326_06565	COG1194	a g-specific adenine glycosylase
MM326_06570	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_06585	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_06595	COG3557	Belongs to the UPF0374 family
MM326_06600	COG1132	(ABC) transporter
MM326_06605	COG4129	membrane
MM326_06610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MM326_06615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MM326_06620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MM326_06630	COG0735	belongs to the Fur family
MM326_06745	COG4974	Belongs to the 'phage' integrase family
MM326_06835	COG0582	viral genome integration into host DNA
MM326_06870	COG2814	Major facilitator Superfamily
MM326_06875	COG1063	alcohol dehydrogenase
MM326_06880	COG1349	DNA-binding transcription factor activity
MM326_06885	COG0698	ribose 5-phosphate isomerase
MM326_06890	COG2376	Dihydroxyacetone kinase
MM326_06895	COG1461	Dihydroxyacetone kinase
MM326_06900	COG1494	fructose-1,6-bisphosphatase
MM326_06905	COG4894	glucomannan catabolic process
MM326_06920	COG0584	glycerophosphoryl diester phosphodiesterase
MM326_06945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MM326_06960	COG1405	negative regulation of cell septum assembly
MM326_06960	COG3012	SEC-C Motif Domain Protein
MM326_06965	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MM326_06970	COG1966	Carbon starvation protein
MM326_06980	COG1012	belongs to the aldehyde dehydrogenase family
MM326_06985	COG1131	(ABC) transporter
MM326_06995	COG1725	Transcriptional regulator
MM326_07000	COG1131	(ABC) transporter
MM326_07010	COG1363	Peptidase, m42
MM326_07015	COG0783	Belongs to the Dps family
MM326_07025	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MM326_07030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MM326_07055	COG2329	Antibiotic biosynthesis monooxygenase
MM326_07060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MM326_07065	COG2766	serine protein kinase
MM326_07080	COG2718	Belongs to the UPF0229 family
MM326_07085	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MM326_07090	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MM326_07100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM326_07110	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_07115	COG2188	Transcriptional regulator
MM326_07120	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MM326_07125	COG0363	glucosamine-6-phosphate deaminase activity
MM326_07130	COG2311	Membrane
MM326_07135	COG0778	Nitroreductase
MM326_07140	COG0179	Fumarylacetoacetate (FAA) hydrolase
MM326_07145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MM326_07145	COG3153	acetyltransferase
MM326_07155	COG1489	DNA binding
MM326_07160	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MM326_07165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MM326_07170	COG2719	SpoVR family
MM326_07175	COG1132	(ABC) transporter
MM326_07180	COG1132	(ABC) transporter
MM326_07185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MM326_07190	COG0501	Belongs to the peptidase M48B family
MM326_07195	COG1704	LemA family
MM326_07200	COG1960	acyl-CoA dehydrogenase activity
MM326_07205	COG0439	Biotin carboxylase
MM326_07210	COG0511	ligase activity, forming carbon-carbon bonds
MM326_07215	COG1024	Enoyl-CoA hydratase
MM326_07220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MM326_07230	COG3842	ATPase activity
MM326_07235	COG2508	Transcriptional regulator
MM326_07250	COG4399	Belongs to the UPF0754 family
MM326_07255	COG3679	Belongs to the UPF0342 family
MM326_07260	COG0561	phosphatase activity
MM326_07275	COG0745	RESPONSE REGULATOR receiver
MM326_07280	COG2770	Histidine kinase
MM326_07280	COG2205	protein histidine kinase activity
MM326_07285	COG3481	metal-dependent phosphohydrolase, HD sub domain
MM326_07295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MM326_07310	COG1846	Transcriptional regulator
MM326_07315	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MM326_07320	COG0537	adenosine 5'-monophosphoramidase activity
MM326_07325	COG1131	(ABC) transporter
MM326_07330	COG4473	ABC transporter
MM326_07340	COG0785	Cytochrome C biogenesis protein
MM326_07345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MM326_07350	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MM326_07355	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MM326_07360	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MM326_07370	COG3290	protein histidine kinase activity
MM326_07375	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MM326_07380	COG4492	Belongs to the UPF0735 family
MM326_07385	COG0077	Prephenate dehydratase
MM326_07390	COG1827	regulation of RNA biosynthetic process
MM326_07395	COG1104	cysteine desulfurase activity
MM326_07400	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MM326_07405	COG0157	Belongs to the NadC ModD family
MM326_07410	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MM326_07415	COG1388	LysM domain
MM326_07435	COG0632	four-way junction helicase activity
MM326_07440	COG2255	four-way junction helicase activity
MM326_07450	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MM326_07455	COG0343	queuine tRNA-ribosyltransferase activity
MM326_07460	COG1862	Preprotein translocase
MM326_07480	COG2244	polysaccharide biosynthetic process
MM326_07490	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MM326_07490	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MM326_07495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MM326_07495	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MM326_07500	COG5416	Lipopolysaccharide assembly protein A domain
MM326_07505	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MM326_07505	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MM326_07510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MM326_07515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MM326_07520	COG1490	D-aminoacyl-tRNA deacylase activity
MM326_07525	COG1609	Transcriptional regulator
MM326_07535	COG0673	inositol 2-dehydrogenase activity
MM326_07545	COG0124	histidyl-tRNA synthetase
MM326_07550	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MM326_07555	COG0460	homoserine dehydrogenase
MM326_07570	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MM326_07580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MM326_07585	COG1959	2 iron, 2 sulfur cluster binding
MM326_07590	COG1104	cysteine desulfurase activity
MM326_07595	COG0482	sulfurtransferase activity
MM326_07605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MM326_07610	COG3881	PFAM PRC-barrel domain
MM326_07625	COG0628	permease
MM326_07630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MM326_07635	COG4472	Bacterial protein of unknown function (DUF965)
MM326_07640	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MM326_07645	COG3906	Belongs to the UPF0473 family
MM326_07650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MM326_07655	COG4122	O-methyltransferase activity
MM326_07660	COG0572	uridine kinase
MM326_07665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MM326_07675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MM326_07685	COG0494	nUDIX hydrolase
MM326_07690	COG0095	Lipoate-protein ligase
MM326_07700	COG1587	Uroporphyrinogen-III synthase
MM326_07705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MM326_07720	COG0776	regulation of translation
MM326_07725	COG1183	phosphatidylcholine synthase activity
MM326_07730	COG0688	phosphatidylethanolamine metabolic process
MM326_07735	COG1320	monovalent cation:proton antiporter activity
MM326_07740	COG2212	antiporter activity
MM326_07745	COG1863	multisubunit Na H antiporter MnhE subunit
MM326_07750	COG0651	ATP synthesis coupled electron transport
MM326_07755	COG1006	Multisubunit Na H antiporter MnhC subunit
MM326_07760	COG2111	Na H antiporter
MM326_07765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MM326_07765	COG2111	Na H antiporter
MM326_07780	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MM326_07785	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MM326_07790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MM326_07795	COG1534	Rna-binding protein
MM326_07800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MM326_07805	COG1713	HD superfamily hydrolase involved in NAD metabolism
MM326_07810	COG0799	negative regulation of ribosome biogenesis
MM326_07815	COG2996	Protein conserved in bacteria
MM326_07820	COG2226	methyltransferase
MM326_07825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MM326_07830	COG1596	polysaccharide export
MM326_07830	COG1555	photosystem II stabilization
MM326_07835	COG2131	deaminase
MM326_07840	COG0658	competence protein
MM326_07840	COG2333	competence protein COMEC
MM326_07850	COG1466	dna polymerase III delta subunit
MM326_07855	COG0268	Binds directly to 16S ribosomal RNA
MM326_07860	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MM326_07870	COG0481	GTPase activity
MM326_07875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MM326_07880	COG1420	regulation of RNA biosynthetic process
MM326_07885	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MM326_07890	COG0443	Heat shock 70 kDa protein
MM326_07895	COG0484	heat shock protein binding
MM326_07900	COG2264	protein methyltransferase activity
MM326_07905	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MM326_07910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MM326_07915	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MM326_07920	COG0667	Aldo Keto reductase
MM326_07930	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MM326_07935	COG1610	YqeY-like protein
MM326_07940	COG1030	water channel activity
MM326_07945	COG4864	UPF0365 protein
MM326_07965	COG1702	phosphate starvation-inducible protein PhoH
MM326_07970	COG1480	7TM receptor with intracellular HD hydrolase
MM326_07975	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MM326_07980	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MM326_07985	COG0295	cytidine deaminase activity
MM326_07990	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MM326_08000	COG1381	Involved in DNA repair and RecF pathway recombination
MM326_08005	COG0752	glycyl-tRNA synthetase alpha subunit
MM326_08010	COG0751	glycine-tRNA ligase activity
MM326_08015	COG0517	IMP dehydrogenase activity
MM326_08020	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MM326_08025	COG1671	Belongs to the UPF0178 family
MM326_08030	COG0358	DNA primase activity
MM326_08035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MM326_08040	COG2010	Cytochrome c
MM326_08045	COG2384	SAM-dependent methyltransferase
MM326_08050	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MM326_08055	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MM326_08060	COG1329	Transcriptional regulator
MM326_08070	COG0513	Belongs to the DEAD box helicase family
MM326_08075	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MM326_08085	COG4191	Histidine kinase
MM326_08095	COG1121	(ABC) transporter
MM326_08100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MM326_08105	COG0735	belongs to the Fur family
MM326_08115	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
MM326_08125	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MM326_08135	COG4086	secreted protein
MM326_08145	COG0704	Plays a role in the regulation of phosphate uptake
MM326_08175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MM326_08185	COG0477	Major facilitator Superfamily
MM326_08195	COG0768	penicillin binding
MM326_08200	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MM326_08215	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MM326_08220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MM326_08230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MM326_08240	COG0457	Tetratricopeptide repeat
MM326_08240	COG0705	Rhomboid family
MM326_08245	COG0697	spore germination
MM326_08260	COG4483	Protein conserved in bacteria
MM326_08265	COG1940	carbohydrate kinase activity
MM326_08270	COG1027	Aspartate ammonia-lyase
MM326_08275	COG0352	thiamine-phosphate diphosphorylase activity
MM326_08285	COG2022	thiamine diphosphate biosynthetic process
MM326_08290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MM326_08295	COG0351	phosphomethylpyrimidine kinase
MM326_08310	COG0011	TIGRFAM Protein of
MM326_08315	COG2153	protein acetylation
MM326_08320	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MM326_08325	COG2382	esterase
MM326_08340	COG1396	sequence-specific DNA binding
MM326_08345	COG0114	fumarate hydratase activity
MM326_08350	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MM326_08360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MM326_08365	COG4191	Histidine kinase
MM326_08375	COG3403	YqcI/YcgG family
MM326_08380	COG4129	membrane
MM326_08385	COG1376	ErfK ybiS ycfS ynhG family protein
MM326_08395	COG0346	lactoylglutathione lyase activity
MM326_08400	COG2195	Cleaves the N-terminal amino acid of tripeptides
MM326_08420	COG0517	IMP dehydrogenase activity
MM326_08430	COG2861	carbohydrate metabolic process
MM326_08435	COG0789	Transcriptional regulator
MM326_08450	COG0527	aspartate kinase activity
MM326_08460	COG0300	oxidoreductase activity
MM326_08465	COG0367	asparagine synthase
MM326_08470	COG0398	Pfam SNARE associated Golgi protein
MM326_08490	COG1562	ergosterol biosynthetic process
MM326_08515	COG2190	(PTS) system
MM326_08520	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
MM326_08525	COG1850	ribulose-bisphosphate carboxylase activity
MM326_08530	COG1968	undecaprenyl-diphosphatase activity
MM326_08535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM326_08545	COG0494	nUDIX hydrolase
MM326_08550	COG1300	Membrane
MM326_08555	COG0735	belongs to the Fur family
MM326_08560	COG1250	3-hydroxyacyl-CoA dehydrogenase
MM326_08560	COG0824	Thioesterase
MM326_08570	COG3246	L-lysine catabolic process to acetate
MM326_08575	COG1510	regulation of RNA biosynthetic process
MM326_08580	COG0517	IMP dehydrogenase activity
MM326_08580	COG1125	glycine betaine transport
MM326_08585	COG1174	glycine betaine transport
MM326_08590	COG1732	Glycine betaine
MM326_08595	COG1174	glycine betaine transport
MM326_08630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MM326_08640	COG1082	Xylose isomerase domain protein TIM barrel
MM326_08650	COG4974	Belongs to the 'phage' integrase family
MM326_08655	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MM326_08665	COG3871	stress protein (general stress protein 26)
MM326_08670	COG1764	response to oxidative stress
MM326_08680	COG2814	Major facilitator Superfamily
MM326_08690	COG1686	Belongs to the peptidase S11 family
MM326_08700	COG2172	sigma factor antagonist activity
MM326_08715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MM326_08730	COG0697	spore germination
MM326_08735	COG0019	diaminopimelate decarboxylase activity
MM326_08740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MM326_08745	COG0583	DNA-binding transcription factor activity
MM326_08755	COG2079	MmgE PrpD family protein
MM326_08760	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MM326_08770	COG1012	belongs to the aldehyde dehydrogenase family
MM326_08775	COG0488	(ABC) transporter
MM326_08780	COG0656	L-ascorbic acid biosynthetic process
MM326_08805	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MM326_08810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MM326_08815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MM326_08820	COG2202	Pas domain
MM326_08820	COG1366	Belongs to the anti-sigma-factor antagonist family
MM326_08825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MM326_08830	COG4876	unkown
MM326_08835	COG1960	acyl-CoA dehydrogenase activity
MM326_08850	COG1366	Belongs to the anti-sigma-factor antagonist family
MM326_08865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MM326_08870	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MM326_08875	COG2226	methyltransferase
MM326_08880	COG3583	domain protein
MM326_08880	COG3584	3D domain protein
MM326_08885	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MM326_08890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MM326_08895	COG1011	Hydrolase
MM326_08905	COG1122	ATPase activity
MM326_08910	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MM326_08915	COG2094	Belongs to the DNA glycosylase MPG family
MM326_08930	COG3844	kynureninase activity
MM326_08935	COG0542	response to heat
MM326_08945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM326_08960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM326_08965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MM326_08970	COG0626	cystathionine gamma-synthase activity
MM326_08975	COG0708	Exodeoxyribonuclease III
MM326_08985	COG0217	transcriptional regulatory protein
MM326_09015	COG2151	metal-sulfur cluster biosynthetic enzyme
MM326_09020	COG0702	epimerase
MM326_09025	COG1757	Na H antiporter
MM326_09035	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MM326_09045	COG1175	transmembrane transport
MM326_09050	COG0395	ABC-type sugar transport system, permease component
MM326_09055	COG1472	Belongs to the glycosyl hydrolase 3 family
MM326_09065	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MM326_09070	COG1473	amidohydrolase
MM326_09090	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MM326_09100	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MM326_09105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MM326_09110	COG2508	Transcriptional regulator
MM326_09120	COG1288	antiporter activity
MM326_09125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MM326_09130	COG1366	Belongs to the anti-sigma-factor antagonist family
MM326_09130	COG2202	Pas domain
MM326_09145	COG1414	Transcriptional regulator
MM326_09150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MM326_09160	COG4948	Mandelate Racemase Muconate Lactonizing
MM326_09165	COG2610	gluconate transmembrane transporter activity
MM326_09220	COG0673	inositol 2-dehydrogenase activity
MM326_09245	COG3708	Transcriptional regulator
MM326_09245	COG2207	Transcriptional regulator
MM326_09260	COG1757	Na H antiporter
MM326_09280	COG3711	transcriptional antiterminator
MM326_09285	COG1263	PTS System
MM326_09285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MM326_09290	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MM326_09295	COG1522	sequence-specific DNA binding
MM326_09300	COG1335	isochorismatase
MM326_09305	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MM326_09310	COG3842	ATPase activity
MM326_09315	COG1176	ABC-type spermidine putrescine transport system, permease component I
MM326_09320	COG3275	phosphorelay sensor kinase activity
MM326_09325	COG4753	response regulator
MM326_09325	COG2207	Transcriptional regulator
MM326_09330	COG2130	NADP-dependent
MM326_09335	COG2814	Major facilitator Superfamily
MM326_09340	COG1714	RDD family
MM326_09345	COG0488	(ABC) transporter
MM326_09355	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MM326_09370	COG1119	ATPase activity
MM326_09400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM326_09405	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM326_09410	COG1120	ATPase activity
MM326_09420	COG0733	neurotransmitter:sodium symporter activity
MM326_09425	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MM326_09430	COG1131	(ABC) transporter
MM326_09435	COG1279	arginine transmembrane transporter activity
MM326_09440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MM326_09445	COG1253	flavin adenine dinucleotide binding
MM326_09450	COG3842	ATPase activity
MM326_09455	COG1175	transmembrane transport
MM326_09465	COG1653	transport
MM326_09470	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MM326_09475	COG3842	ATPase activity
MM326_09480	COG1177	transmembrane transport
MM326_09485	COG1176	ABC-type spermidine putrescine transport system, permease component I
MM326_09505	COG3964	amidohydrolase
MM326_09525	COG2188	Transcriptional regulator
MM326_09590	COG0067	glutamate synthase
MM326_09590	COG0070	glutamate synthase
MM326_09590	COG0069	glutamate synthase activity
MM326_09595	COG0493	'glutamate synthase
MM326_09620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MM326_09640	COG0400	carboxylic ester hydrolase activity
MM326_09680	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MM326_09680	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MM326_09685	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MM326_09690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MM326_09695	COG0277	FAD linked oxidase domain protein
MM326_09710	COG0318	PFAM AMP-dependent synthetase and ligase
MM326_09725	COG1414	Transcriptional regulator
MM326_09765	COG0436	Aminotransferase
MM326_09785	COG0460	homoserine dehydrogenase
MM326_09810	COG0513	Belongs to the DEAD box helicase family
MM326_09825	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_09830	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MM326_09830	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MM326_09840	COG1388	LysM domain
MM326_09845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM326_09850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MM326_09855	COG1360	Flagellar Motor Protein
MM326_09860	COG0628	permease
MM326_09865	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MM326_09870	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MM326_09875	COG1131	(ABC) transporter
MM326_09880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MM326_09885	COG0187	DNA topoisomerase II activity
MM326_09890	COG1832	CoA-binding protein
MM326_09895	COG1174	glycine betaine transport
MM326_09900	COG1125	glycine betaine transport
MM326_09900	COG0517	IMP dehydrogenase activity
MM326_09905	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_09910	COG4974	Belongs to the 'phage' integrase family
MM326_09920	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MM326_09935	COG1070	Carbohydrate kinase
MM326_09945	COG0116	Belongs to the methyltransferase superfamily
MM326_09960	COG0328	RNA-DNA hybrid ribonuclease activity
MM326_09965	COG3599	regulation of cell shape
MM326_09970	COG4474	Belongs to the UPF0398 family
MM326_09980	COG3359	exonuclease
MM326_09985	COG1111	helicase
MM326_09985	COG1205	dead DEAH box helicase
MM326_10000	COG0400	carboxylic ester hydrolase activity
MM326_10020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MM326_10045	COG0493	'glutamate synthase
MM326_10050	COG0069	glutamate synthase activity
MM326_10050	COG0070	glutamate synthase
MM326_10050	COG0067	glutamate synthase
MM326_10070	COG3428	Bacterial PH domain
MM326_10075	COG3402	PFAM membrane-flanked domain
MM326_10085	COG1413	lyase activity
MM326_10110	COG1234	tRNA 3'-trailer cleavage
MM326_10115	COG0693	protein deglycase activity
MM326_10120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MM326_10135	COG0789	Transcriptional regulator
MM326_10150	COG3331	DNA recombination
MM326_10155	COG4499	WXG100 protein secretion system (Wss), protein YukC
MM326_10155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MM326_10160	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MM326_10170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MM326_10175	COG3935	DnaD domain protein
MM326_10180	COG0017	Asparaginyl-tRNA synthetase
MM326_10200	COG0402	S-adenosylhomocysteine deaminase activity
MM326_10205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MM326_10205	COG1199	ATP-dependent helicase activity
MM326_10215	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MM326_10220	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MM326_10225	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MM326_10235	COG0617	tRNA 3'-terminal CCA addition
MM326_10240	COG0438	transferase activity, transferring glycosyl groups
MM326_10245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MM326_10255	COG1803	Methylglyoxal synthase
MM326_10260	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MM326_10265	COG1694	Mazg nucleotide pyrophosphohydrolase
MM326_10270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM326_10275	COG2738	Putative neutral zinc metallopeptidase
MM326_10285	COG4347	Protein of unknown function (DUF1405)
MM326_10290	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MM326_10290	COG2010	Cytochrome c
MM326_10295	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MM326_10300	COG0723	plastoquinol--plastocyanin reductase activity
MM326_10310	COG5582	Belongs to the UPF0302 family
MM326_10315	COG0457	Tetratricopeptide repeat
MM326_10320	COG0287	Prephenate dehydrogenase
MM326_10325	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MM326_10330	COG0159	tryptophan synthase activity
MM326_10335	COG0133	tryptophan synthase activity
MM326_10345	COG0134	indole-3-glycerol-phosphate synthase activity
MM326_10350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MM326_10360	COG4401	Chorismate mutase type I
MM326_10365	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MM326_10370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MM326_10375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MM326_10380	COG0105	UTP biosynthetic process
MM326_10385	COG0142	geranyltranstransferase activity
MM326_10390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MM326_10395	COG2226	methyltransferase
MM326_10410	COG0302	gtp cyclohydrolase
MM326_10415	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MM326_10435	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MM326_10440	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MM326_10445	COG1160	GTP binding
MM326_10455	COG0539	negative regulation of cytoplasmic translation
MM326_10460	COG0204	Acyl-transferase
MM326_10465	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MM326_10470	COG2959	enzyme of heme biosynthesis
MM326_10475	COG3773	Cell wall hydrolase
MM326_10475	COG3409	Peptidoglycan-binding domain 1 protein
MM326_10480	COG0646	methionine synthase
MM326_10480	COG1410	methionine synthase
MM326_10485	COG0646	methionine synthase
MM326_10485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MM326_10490	COG0626	cystathionine gamma-synthase activity
MM326_10500	COG2339	peptidase activity
MM326_10510	COG0492	ferredoxin-NADP+ reductase activity
MM326_10515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MM326_10525	COG3850	Histidine kinase
MM326_10525	COG5002	protein histidine kinase activity
MM326_10530	COG0745	RESPONSE REGULATOR receiver
MM326_10535	COG4862	establishment of competence for transformation
MM326_10545	COG1473	amidohydrolase
MM326_10560	COG1396	sequence-specific DNA binding
MM326_10575	COG0514	ATP-dependent DNA helicase (RecQ)
MM326_10585	COG1141	Ferredoxin
MM326_10590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MM326_10600	COG2096	Adenosyltransferase
MM326_10605	COG1120	ATPase activity
MM326_10610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM326_10615	COG5002	protein histidine kinase activity
MM326_10620	COG0745	RESPONSE REGULATOR receiver
MM326_10625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MM326_10630	COG1333	cytochrome c biogenesis protein
MM326_10635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM326_10640	COG1187	pseudouridine synthase activity
MM326_10645	COG0700	Nucleoside recognition
MM326_10650	COG2715	membrane protein required for spore maturation
MM326_10655	COG1686	Belongs to the peptidase S11 family
MM326_10670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MM326_10685	COG2323	membrane
MM326_10695	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MM326_10700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MM326_10705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MM326_10710	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MM326_10715	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MM326_10725	COG2116	formate transmembrane transporter activity
MM326_10730	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MM326_10735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MM326_10735	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MM326_10740	COG0307	riboflavin synthase, alpha
MM326_10745	COG1024	Enoyl-CoA hydratase
MM326_10755	COG0508	dehydrogenase complex catalyzes the overall conversion of
MM326_10760	COG0567	Dehydrogenase, E1 component
MM326_10790	COG1764	response to oxidative stress
MM326_10795	COG1305	Transglutaminase-like
MM326_10805	COG2308	Evidence 4 Homologs of previously reported genes of
MM326_10815	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MM326_10820	COG0602	queuosine metabolic process
MM326_10825	COG0720	synthase
MM326_10830	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MM326_10835	COG2309	aminopeptidase activity
MM326_10845	COG1254	Belongs to the acylphosphatase family
MM326_10865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MM326_10885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MM326_10900	COG0835	chemotaxis
MM326_10900	COG0784	Response regulator, receiver
MM326_10925	COG2200	EAL domain
MM326_10930	COG2267	carboxylic ester hydrolase activity
MM326_10945	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MM326_10950	COG0824	Thioesterase
MM326_10980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MM326_11010	COG1132	(ABC) transporter
MM326_11015	COG1132	(ABC) transporter
MM326_11020	COG3763	UPF0154 protein
MM326_11030	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MM326_11035	COG4224	UPF0291 protein
MM326_11040	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MM326_11050	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MM326_11055	COG2814	Major facilitator Superfamily
MM326_11110	COG4974	Belongs to the 'phage' integrase family
MM326_11115	COG0174	glutamine synthetase
MM326_11120	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MM326_11125	COG0464	growth
MM326_11135	COG1923	regulation of RNA biosynthetic process
MM326_11145	COG2521	methyltransferase
MM326_11145	COG2136	Putative SAM-dependent methyltransferase
MM326_11150	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MM326_11155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MM326_11165	COG4550	Control of competence regulator ComK, YlbF/YmcA
MM326_11170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MM326_11180	COG2359	stage V sporulation protein S
MM326_11185	COG1692	metallophosphoesterase
MM326_11190	COG1418	mRNA catabolic process
MM326_11215	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MM326_11220	COG0513	Belongs to the DEAD box helicase family
MM326_11225	COG1546	Belongs to the CinA family
MM326_11225	COG1058	Belongs to the CinA family
MM326_11230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MM326_11235	COG1426	Protein conserved in bacteria
MM326_11250	COG0300	oxidoreductase activity
MM326_11255	COG0612	Peptidase, M16
MM326_11260	COG0612	Peptidase, M16
MM326_11265	COG1674	ftsk spoiiie
MM326_11275	COG0740	serine-type endopeptidase activity
MM326_11280	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MM326_11285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MM326_11290	COG0527	aspartate kinase activity
MM326_11295	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MM326_11300	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MM326_11305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MM326_11310	COG1873	PFAM PRC-barrel domain
MM326_11315	COG0612	Peptidase, M16
MM326_11320	COG0726	polysaccharide deacetylase
MM326_11325	COG1185	polyribonucleotide nucleotidyltransferase activity
MM326_11330	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MM326_11335	COG0196	riboflavin kinase activity
MM326_11340	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MM326_11345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MM326_11350	COG1550	Protein conserved in bacteria
MM326_11355	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MM326_11360	COG1358	cellular component organization or biogenesis
MM326_11365	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MM326_11370	COG0195	Participates in both transcription termination and antitermination
MM326_11375	COG0779	Required for maturation of 30S ribosomal subunits
MM326_11380	COG2176	DNA-directed DNA polymerase activity
MM326_11385	COG0442	prolyl-tRNA aminoacylation
MM326_11390	COG0750	zinc metalloprotease
MM326_11395	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MM326_11400	COG4589	Belongs to the CDS family
MM326_11405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MM326_11410	COG0233	cytoplasmic translational termination
MM326_11415	COG0528	UMP kinase activity
MM326_11420	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MM326_11425	COG0052	Belongs to the universal ribosomal protein uS2 family
MM326_11435	COG1191	sigma factor activity
MM326_11440	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MM326_11445	COG1776	CheC inhibitor of MCP methylation
MM326_11450	COG2201	protein-glutamate methylesterase activity
MM326_11460	COG1419	protein localization to endoplasmic reticulum
MM326_11465	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MM326_11470	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MM326_11475	COG1684	flagellar biosynthetic protein fliR
MM326_11480	COG1987	bacterial-type flagellum assembly
MM326_11485	COG1338	Plays a role in the flagellum-specific transport system
MM326_11490	COG3190	flagellar
MM326_11495	COG2201	protein-glutamate methylesterase activity
MM326_11500	COG1776	CheC inhibitor of MCP methylation
MM326_11500	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MM326_11505	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MM326_11520	COG4786	Flagellar basal body rod
MM326_11545	COG1157	protein secretion by the type III secretion system
MM326_11550	COG1317	bacterial-type flagellum organization
MM326_11555	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MM326_11560	COG1766	The M ring may be actively involved in energy transduction
MM326_11565	COG1677	Flagellar hook-basal body complex protein FliE
MM326_11570	COG1558	bacterial-type flagellum-dependent cell motility
MM326_11575	COG1815	bacterial-type flagellum-dependent cell motility
MM326_11580	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MM326_11585	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MM326_11590	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MM326_11595	COG4974	Belongs to the 'phage' integrase family
MM326_11600	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MM326_11605	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MM326_11610	COG0758	DNA mediated transformation
MM326_11615	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MM326_11620	COG0045	succinate-CoA ligase (ADP-forming) activity
MM326_11635	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MM326_11660	COG0335	large ribosomal subunit rRNA binding
MM326_11665	COG0018	arginyl-trna synthetase
MM326_11670	COG0336	Belongs to the RNA methyltransferase TrmD family
MM326_11675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MM326_11685	COG1837	Belongs to the UPF0109 family
MM326_11690	COG0228	four-way junction DNA binding
MM326_11695	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MM326_11700	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MM326_11705	COG0552	protein localization to endoplasmic reticulum
MM326_11710	COG1196	nuclear chromosome segregation
MM326_11720	COG0571	ribonuclease III activity
MM326_11725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MM326_11730	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_11735	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MM326_11740	COG0416	fatty acid biosynthetic process
MM326_11745	COG1349	DNA-binding transcription factor activity
MM326_11750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MM326_11755	COG1760	l-serine dehydratase
MM326_11760	COG1760	l-serine dehydratase
MM326_11765	COG1307	EDD domain protein, DegV family
MM326_11770	COG1461	Dihydroxyacetone kinase
MM326_11775	COG1302	Protein conserved in bacteria
MM326_11780	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MM326_11790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MM326_11795	COG1162	GTPase activity
MM326_11800	COG0515	serine threonine protein kinase
MM326_11800	COG2815	serine threonine protein kinase
MM326_11810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MM326_11810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MM326_11815	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MM326_11820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MM326_11825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MM326_11830	COG1758	RNA polymerase activity
MM326_11835	COG0194	GDP metabolic process
MM326_11840	COG2052	Domain of unknown function (DUF370)
MM326_11845	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MM326_11860	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MM326_11865	COG0284	orotidine-5'-phosphate decarboxylase activity
MM326_11870	COG0167	dihydroorotate dehydrogenase activity
MM326_11875	COG0543	2 iron, 2 sulfur cluster binding
MM326_11880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MM326_11885	COG0505	Belongs to the CarA family
MM326_11890	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MM326_11895	COG0540	Belongs to the ATCase OTCase family
MM326_11900	COG2233	PERMEase
MM326_11905	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MM326_11910	COG0564	pseudouridine synthase activity
MM326_11915	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MM326_11920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MM326_11925	COG3599	regulation of cell shape
MM326_11930	COG2302	S4 RNA-binding domain
MM326_11935	COG0762	integral membrane protein
MM326_11940	COG1799	cell septum assembly
MM326_11945	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MM326_11950	COG1496	oxidoreductase activity
MM326_11955	COG1873	PFAM PRC-barrel domain
MM326_11960	COG1191	sigma factor activity
MM326_11965	COG1191	sigma factor activity
MM326_11975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MM326_11980	COG0849	cell division
MM326_11985	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MM326_11990	COG0772	Belongs to the SEDS family
MM326_11995	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MM326_12000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MM326_12005	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MM326_12010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MM326_12015	COG0768	penicillin binding
MM326_12020	COG0768	penicillin binding
MM326_12030	COG0275	rRNA processing
MM326_12035	COG2001	Belongs to the MraZ family
MM326_12040	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MM326_12045	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MM326_12050	COG0454	-acetyltransferase
MM326_12060	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MM326_12065	COG1399	metal-binding, possibly nucleic acid-binding protein
MM326_12070	COG1323	Belongs to the UPF0348 family
MM326_12075	COG3480	Lon protease (S16) C-terminal proteolytic domain
MM326_12080	COG1752	Esterase of the alpha-beta hydrolase superfamily
MM326_12085	COG3314	Sporulation integral membrane protein YlbJ
MM326_12090	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MM326_12095	COG0742	ribosomal rna small subunit methyltransferase
MM326_12105	COG4471	UPF0298 protein
MM326_12110	COG3679	Belongs to the UPF0342 family
MM326_12135	COG2340	Cysteine-rich secretory protein family
MM326_12150	COG2322	membrane
MM326_12155	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MM326_12160	COG1845	cytochrome c oxidase, subunit III
MM326_12165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MM326_12170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MM326_12170	COG2010	Cytochrome c
MM326_12175	COG1612	heme a metabolic process
MM326_12180	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MM326_12185	COG4838	Belongs to the UPF0358 family
MM326_12190	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MM326_12195	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MM326_12200	COG4896	Protein conserved in bacteria
MM326_12210	COG1217	gtp-binding protein TYPA
MM326_12225	COG0483	inositol monophosphate 1-phosphatase activity
MM326_12235	COG4493	Belongs to the UPF0637 family
MM326_12240	COG4476	Belongs to the UPF0223 family
MM326_12245	COG1982	Orn Lys Arg decarboxylase major
MM326_12255	COG0726	polysaccharide deacetylase
MM326_12260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MM326_12270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MM326_12275	COG0601	transmembrane transport
MM326_12285	COG4608	Belongs to the ABC transporter superfamily
MM326_12290	COG0444	Belongs to the ABC transporter superfamily
MM326_12300	COG0508	dehydrogenase complex catalyzes the overall conversion of
MM326_12305	COG0022	dehydrogenase e1 component
MM326_12315	COG0497	DNA recombination
MM326_12325	COG0242	peptide deformylase activity
MM326_12330	COG5503	Protein of unknown function (DUF1447)
MM326_12335	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MM326_12340	COG0668	transmembrane transport
MM326_12350	COG1473	amidohydrolase
MM326_12355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MM326_12360	COG2171	N-acyltransferase activity
MM326_12375	COG0668	transmembrane transport
MM326_12390	COG0628	permease
MM326_12395	COG0702	epimerase
MM326_12400	COG1902	pentaerythritol trinitrate reductase activity
MM326_12415	COG2608	mercury ion transmembrane transporter activity
MM326_12420	COG1937	Protein conserved in bacteria
MM326_12425	COG0561	phosphatase activity
MM326_12445	COG0508	dehydrogenase complex catalyzes the overall conversion of
MM326_12450	COG0022	dehydrogenase e1 component
MM326_12455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MM326_12460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MM326_12470	COG3290	protein histidine kinase activity
MM326_12470	COG3829	transcription factor binding
MM326_12485	COG0745	RESPONSE REGULATOR receiver
MM326_12490	COG0750	zinc metalloprotease
MM326_12495	COG0497	DNA recombination
MM326_12500	COG1438	arginine binding
MM326_12505	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MM326_12510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MM326_12515	COG0142	geranyltranstransferase activity
MM326_12520	COG1722	exodeoxyribonuclease VII activity
MM326_12525	COG1570	exodeoxyribonuclease VII activity
MM326_12530	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MM326_12535	COG1302	Protein conserved in bacteria
MM326_12540	COG0439	Biotin carboxylase
MM326_12545	COG0511	ligase activity, forming carbon-carbon bonds
MM326_12590	COG3854	ATPases associated with a variety of cellular activities
MM326_12600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MM326_12605	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MM326_12610	COG0006	proline dipeptidase activity
MM326_12625	COG1752	Esterase of the alpha-beta hydrolase superfamily
MM326_12630	COG1321	iron dependent repressor
MM326_12635	COG1533	DNA photolyase activity
MM326_12645	COG3973	AAA domain
MM326_12650	COG0095	Lipoate-protein ligase
MM326_12655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MM326_12660	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MM326_12665	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MM326_12670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MM326_12675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MM326_12690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM326_12720	COG4537	Required for transformation and DNA binding
MM326_12725	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MM326_12775	COG1459	type II secretion system
MM326_12780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MM326_12785	COG1403	HNH endonuclease
MM326_12790	COG0210	DNA helicase
MM326_12795	COG1216	Glycosyl transferase, family 2
MM326_12800	COG0463	Glycosyl transferase, family 2
MM326_12800	COG0457	Tetratricopeptide repeat
MM326_12805	COG0463	Glycosyl transferase, family 2
MM326_12815	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MM326_12815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MM326_12835	COG4641	Protein conserved in bacteria
MM326_12855	COG0564	pseudouridine synthase activity
MM326_12860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MM326_12865	COG2357	RelA SpoT domain protein
MM326_12880	COG0741	lytic transglycosylase activity
MM326_12885	COG2346	COG2346, Truncated hemoglobins
MM326_12890	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MM326_12900	COG1164	Oligoendopeptidase f
MM326_12910	COG4862	establishment of competence for transformation
MM326_12915	COG1393	Belongs to the ArsC family
MM326_12925	COG0456	acetyltransferase
MM326_12940	COG1272	protein, Hemolysin III
MM326_12945	COG1418	mRNA catabolic process
MM326_12950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM326_12960	COG0180	Tryptophanyl-tRNA synthetase
MM326_12965	COG1846	Transcriptional regulator
MM326_12975	COG5504	Zn-dependent protease
MM326_12980	COG1072	(Pantothenic acid kinase))
MM326_12985	COG2340	Cysteine-rich secretory protein family
MM326_12990	COG3773	Cell wall hydrolase
MM326_12990	COG3409	Peptidoglycan-binding domain 1 protein
MM326_13000	COG0617	tRNA 3'-terminal CCA addition
MM326_13000	COG3620	sequence-specific DNA binding
MM326_13000	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MM326_13005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MM326_13010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MM326_13025	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MM326_13045	COG2267	carboxylic ester hydrolase activity
MM326_13055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MM326_13060	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MM326_13065	COG0505	Belongs to the CarA family
MM326_13070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MM326_13075	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MM326_13080	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MM326_13085	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MM326_13095	COG3336	cytochrome c oxidase
MM326_13100	COG0561	phosphatase activity
MM326_13115	COG4715	Zinc finger, swim domain protein
MM326_13120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MM326_13135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM326_13140	COG1073	alpha beta
MM326_13150	COG0301	tRNA thio-modification
MM326_13150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MM326_13160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MM326_13165	COG1834	amidinotransferase
MM326_13175	COG0367	asparagine synthase
MM326_13185	COG2198	Histidine kinase
MM326_13185	COG0643	Histidine kinase
MM326_13195	COG0704	Plays a role in the regulation of phosphate uptake
MM326_13200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MM326_13205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MM326_13210	COG0581	inorganic phosphate transmembrane transporter activity
MM326_13215	COG0573	inorganic phosphate transmembrane transporter activity
MM326_13220	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MM326_13225	COG2318	DinB family
MM326_13235	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MM326_13240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MM326_13255	COG1228	amidohydrolase
MM326_13260	COG2002	toxin-antitoxin pair type II binding
MM326_13265	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MM326_13270	COG2868	ribosomal protein
MM326_13275	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MM326_13280	COG1530	ribonuclease E activity
MM326_13285	COG1994	Peptidase M50
MM326_13295	COG0667	Aldo Keto reductase
MM326_13300	COG1268	BioY protein
MM326_13305	COG0315	cyclic pyranopterin monophosphate synthase activity
MM326_13310	COG2894	cell division
MM326_13315	COG0850	regulation of cytokinetic process
MM326_13320	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MM326_13330	COG1077	Cell shape determining protein MreB Mrl
MM326_13335	COG2003	Belongs to the UPF0758 family
MM326_13340	COG0424	maF-like protein
MM326_13345	COG0823	Involved in the tonB-independent uptake of proteins
MM326_13345	COG4946	Tricorn protease homolog
MM326_13345	COG1506	peptidase
MM326_13355	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MM326_13360	COG0285	dihydrofolate synthase activity
MM326_13365	COG0525	valine-tRNA ligase activity
MM326_13390	COG1388	LysM domain
MM326_13390	COG1388	LysM domain
MM326_13395	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MM326_13400	COG0113	porphobilinogen synthase activity
MM326_13410	COG0181	hydroxymethylbilane synthase activity
MM326_13415	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MM326_13420	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MM326_13425	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MM326_13430	COG1067	ATP-dependent peptidase activity
MM326_13430	COG0470	DNA polymerase III
MM326_13435	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MM326_13440	COG0544	peptidyl-prolyl cis-trans isomerase activity
MM326_13445	COG1477	protein flavinylation
MM326_13445	COG0457	Tetratricopeptide repeat
MM326_13450	COG0066	3-isopropylmalate dehydratase activity
MM326_13455	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MM326_13460	COG0473	3-isopropylmalate dehydrogenase activity
MM326_13465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MM326_13470	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MM326_13475	COG0440	acetolactate synthase activity
MM326_13480	COG0028	Belongs to the TPP enzyme family
MM326_13485	COG0129	dihydroxy-acid dehydratase activity
MM326_13505	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MM326_13570	COG5434	Belongs to the glycosyl hydrolase 28 family
MM326_13675	COG0582	viral genome integration into host DNA
MM326_13745	COG1793	dna ligase
MM326_13770	COG3584	3D domain protein
MM326_13780	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
MM326_13785	COG0756	dUTP diphosphatase activity
MM326_13820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MM326_13825	COG1780	Probably involved in ribonucleotide reductase function
MM326_13835	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MM326_13850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MM326_13850	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MM326_13965	COG1475	DNA binding
MM326_13990	COG4974	Belongs to the 'phage' integrase family
MM326_14005	COG0622	Phosphoesterase
MM326_14010	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MM326_14015	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MM326_14020	COG5401	PFAM Sporulation and spore germination
MM326_14025	COG1054	Belongs to the UPF0176 family
MM326_14035	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MM326_14040	COG1846	Transcriptional regulator
MM326_14045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MM326_14050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM326_14055	COG2197	response regulator
MM326_14065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MM326_14070	COG1053	succinate dehydrogenase
MM326_14075	COG2009	succinate dehydrogenase
MM326_14085	COG0322	excinuclease ABC activity
MM326_14090	COG3118	belongs to the thioredoxin family
MM326_14095	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MM326_14100	COG2086	electron transfer activity
MM326_14105	COG1024	Enoyl-CoA hydratase
MM326_14110	COG1309	transcriptional regulator
MM326_14115	COG0318	PFAM AMP-dependent synthetase and ligase
MM326_14120	COG3766	membrane
MM326_14125	COG1193	negative regulation of DNA recombination
MM326_14130	COG1796	DNA polymerase
MM326_14130	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MM326_14135	COG1286	toxin biosynthetic process
MM326_14140	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MM326_14145	COG0072	phenylalanine-tRNA ligase activity
MM326_14150	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MM326_14155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MM326_14175	COG1363	Peptidase, m42
MM326_14185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MM326_14190	COG3162	membrane
MM326_14195	COG0398	Pfam SNARE associated Golgi protein
MM326_14205	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MM326_14210	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MM326_14215	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MM326_14220	COG0577	efflux transmembrane transporter activity
MM326_14225	COG1136	(ABC) transporter
MM326_14230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MM326_14245	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MM326_14245	COG0456	acetyltransferase
MM326_14255	COG0656	L-ascorbic acid biosynthetic process
MM326_14265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MM326_14275	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MM326_14280	COG1484	DNA-dependent DNA replication
MM326_14285	COG3611	Membrane attachment protein
MM326_14290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MM326_14300	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MM326_14305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MM326_14310	COG0237	dephospho-CoA kinase activity
MM326_14315	COG1971	Probably functions as a manganese efflux pump
MM326_14320	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MM326_14325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MM326_14325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MM326_14330	COG5002	protein histidine kinase activity
MM326_14335	COG0745	RESPONSE REGULATOR receiver
MM326_14340	COG1522	sequence-specific DNA binding
MM326_14350	COG0039	L-malate dehydrogenase activity
MM326_14355	COG0538	isocitrate dehydrogenase activity
MM326_14360	COG0372	Belongs to the citrate synthase family
MM326_14365	COG3030	protein affecting phage T7 exclusion by the F plasmid
MM326_14375	COG0205	6-phosphofructokinase activity
MM326_14380	COG0825	malonyl-CoA metabolic process
MM326_14385	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MM326_14390	COG2186	Transcriptional regulator
MM326_14395	COG0281	malic enzyme
MM326_14400	COG0587	DNA-directed DNA polymerase activity
MM326_14415	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MM326_14425	COG4109	DRTGG domain
MM326_14435	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MM326_14440	COG0006	proline dipeptidase activity
MM326_14450	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_14460	COG0165	Argininosuccinate lyase
MM326_14465	COG0137	argininosuccinate synthase activity
MM326_14480	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MM326_14485	COG0827	DNA restriction-modification system
MM326_14490	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MM326_14495	COG3874	Sporulation protein YtfJ
MM326_14505	COG1714	RDD family
MM326_14510	COG0616	signal peptide processing
MM326_14515	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MM326_14525	COG0301	tRNA thio-modification
MM326_14530	COG1104	cysteine desulfurase activity
MM326_14535	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MM326_14540	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MM326_14545	COG1309	transcriptional regulator
MM326_14550	COG1956	GAF domain-containing protein
MM326_14555	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MM326_14560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MM326_14565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MM326_14570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MM326_14575	COG0454	-acetyltransferase
MM326_14580	COG0517	IMP dehydrogenase activity
MM326_14585	COG0123	including yeast histone deacetylase and acetoin utilization protein
MM326_14595	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_14610	COG1960	acyl-CoA dehydrogenase activity
MM326_14620	COG0410	ABC transporter
MM326_14635	COG0559	Belongs to the binding-protein-dependent transport system permease family
MM326_14640	COG0318	PFAM AMP-dependent synthetase and ligase
MM326_14645	COG0183	Belongs to the thiolase family
MM326_14655	COG1605	Chorismate mutase
MM326_14655	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MM326_14660	COG4980	gas vesicle protein
MM326_14670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MM326_14675	COG1674	ftsk spoiiie
MM326_14680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MM326_14685	COG4848	Belongs to the UPF0354 family
MM326_14690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM326_14705	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
MM326_14710	COG1363	Peptidase, m42
MM326_14720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MM326_14730	COG0510	thiamine kinase activity
MM326_14735	COG0788	formyltetrahydrofolate deformylase activity
MM326_14740	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_14750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MM326_14755	COG1349	DNA-binding transcription factor activity
MM326_14760	COG1187	pseudouridine synthase activity
MM326_14765	COG0772	Belongs to the SEDS family
MM326_14770	COG0772	Belongs to the SEDS family
MM326_14775	COG2244	polysaccharide biosynthetic process
MM326_14780	COG3386	PFAM SMP-30 Gluconolaconase
MM326_14785	COG0432	Pfam Uncharacterised protein family UPF0047
MM326_14790	COG1473	amidohydrolase
MM326_14795	COG2081	HI0933 family
MM326_14800	COG0495	leucyl-tRNA aminoacylation
MM326_14805	COG2814	Major facilitator Superfamily
MM326_14810	COG1242	4 iron, 4 sulfur cluster binding
MM326_14815	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MM326_14820	COG0288	reversible hydration of carbon dioxide
MM326_14830	COG2267	carboxylic ester hydrolase activity
MM326_14835	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MM326_14840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MM326_14845	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MM326_14850	COG1506	peptidase
MM326_14855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MM326_14860	COG1116	anion transmembrane transporter activity
MM326_14865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MM326_14870	COG0494	nUDIX hydrolase
MM326_14875	COG2814	Major facilitator Superfamily
MM326_14885	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MM326_14890	COG1428	Deoxynucleoside kinase
MM326_14895	COG1428	Deoxynucleoside kinase
MM326_14905	COG4607	ABC-type enterochelin transport system periplasmic component
MM326_14910	COG4604	ABC transporter, ATP-binding protein
MM326_14915	COG4605	iron ion homeostasis
MM326_14920	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM326_14925	COG0671	phosphoesterase, PA-phosphatase related
MM326_14945	COG4846	Membrane protein involved in cytochrome C biogenesis
MM326_14950	COG0109	protoheme IX farnesyltransferase activity
MM326_14955	COG1227	inorganic diphosphatase activity
MM326_14975	COG2610	gluconate transmembrane transporter activity
MM326_14980	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MM326_14985	COG3395	kinase activity
MM326_14990	COG1349	DNA-binding transcription factor activity
MM326_15190	COG4824	toxin secretion phage lysis holin
MM326_15225	COG0739	heme binding
MM326_15225	COG0741	lytic transglycosylase activity
MM326_15225	COG1196	nuclear chromosome segregation
MM326_15270	COG0740	serine-type endopeptidase activity
MM326_15285	COG1802	Transcriptional regulator
MM326_15285	COG4626	Terminase
MM326_15315	COG0582	viral genome integration into host DNA
MM326_15345	COG0166	Belongs to the GPI family
MM326_15350	COG1181	Belongs to the D-alanine--D-alanine ligase family
MM326_15355	COG1979	alcohol dehydrogenase
MM326_15360	COG2155	Conserved Protein
MM326_15365	COG1098	S1 RNA binding domain
MM326_15375	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MM326_15380	COG0436	Aminotransferase
MM326_15385	COG1522	sequence-specific DNA binding
MM326_15390	COG1335	isochorismatase
MM326_15395	COG1854	S-ribosylhomocysteine lyase activity
MM326_15400	COG1295	ribonuclease BN
MM326_15405	COG0776	regulation of translation
MM326_15410	COG2056	Na+-H+ antiporter family
MM326_15420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MM326_15425	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
MM326_15430	COG3584	3D domain protein
MM326_15440	COG1252	NADH dehydrogenase
MM326_15445	COG0492	ferredoxin-NADP+ reductase activity
MM326_15450	COG0246	Mannitol dehydrogenase
MM326_15455	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM326_15460	COG3711	transcriptional antiterminator
MM326_15470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM326_15475	COG0765	amino acid transport
MM326_15480	COG0316	Belongs to the HesB IscA family
MM326_15490	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MM326_15495	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MM326_15505	COG4844	belongs to the
MM326_15515	COG1252	NADH dehydrogenase
MM326_15520	COG4837	Protein of unknown function (DUF1462)
MM326_15525	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MM326_15540	COG0083	homoserine kinase activity
MM326_15545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MM326_15550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MM326_15555	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MM326_15565	COG2445	Protein of unknown function DUF86
MM326_15575	COG4470	Protein conserved in bacteria
MM326_15585	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MM326_15590	COG0739	heme binding
MM326_15595	COG1757	Na H antiporter
MM326_15610	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MM326_15615	COG3377	Domain of unknown function (DUF1805)
MM326_15620	COG0737	Belongs to the 5'-nucleotidase family
MM326_15625	COG0730	response to heat
MM326_15630	COG1801	Protein of unknown function DUF72
MM326_15640	COG0719	Fe-S assembly protein
MM326_15645	COG0822	iron-sulfur transferase activity
MM326_15650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MM326_15655	COG0719	Fe-S assembly protein
MM326_15660	COG0396	ATPase activity
MM326_15670	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MM326_15675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MM326_15685	COG1464	Belongs to the NlpA lipoprotein family
MM326_15690	COG2011	ABC-type metal ion transport system permease component
MM326_15695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MM326_15700	COG2814	Major facilitator Superfamily
MM326_15710	COG0509	glycine decarboxylation via glycine cleavage system
MM326_15715	COG1393	Belongs to the ArsC family
MM326_15720	COG1960	acyl-CoA dehydrogenase activity
MM326_15725	COG0183	Belongs to the thiolase family
MM326_15730	COG1024	Enoyl-CoA hydratase
MM326_15730	COG1250	3-hydroxyacyl-CoA dehydrogenase
MM326_15740	COG5577	PFAM Coat F domain
MM326_15745	COG0753	catalase activity
MM326_15755	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MM326_15760	COG3314	Sporulation integral membrane protein YlbJ
MM326_15775	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MM326_15780	COG2259	Doxx family
MM326_15785	COG0557	exoribonuclease II activity
MM326_15790	COG1647	Serine aminopeptidase, S33
MM326_15800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM326_15805	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MM326_15815	COG0163	prenyltransferase activity
MM326_15820	COG1785	Belongs to the alkaline phosphatase family
MM326_15825	COG0148	phosphopyruvate hydratase activity
MM326_15830	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MM326_15835	COG0149	triose-phosphate isomerase activity
MM326_15840	COG0126	phosphoglycerate kinase activity
MM326_15845	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MM326_15860	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MM326_15865	COG0740	serine-type endopeptidase activity
MM326_15875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MM326_15880	COG1481	regulation of sporulation
MM326_15885	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MM326_15890	COG1660	Displays ATPase and GTPase activities
MM326_15895	COG1051	belongs to the nudix hydrolase family
MM326_15900	COG0492	ferredoxin-NADP+ reductase activity
MM326_15910	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MM326_15910	COG0140	phosphoribosyl-ATP diphosphatase activity
MM326_15915	COG0107	imidazoleglycerol-phosphate synthase activity
MM326_15920	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MM326_15925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MM326_15930	COG0131	Imidazoleglycerol-phosphate dehydratase
MM326_15935	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MM326_15940	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MM326_15945	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MM326_15950	COG0110	maltose O-acetyltransferase activity
MM326_15960	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MM326_15965	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MM326_15970	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MM326_15975	COG1950	PFAM Membrane protein of
MM326_15980	COG1983	PspC domain protein
MM326_15985	COG3595	metallopeptidase activity
MM326_15990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MM326_15995	COG0556	nucleotide-excision repair
MM326_16010	COG0793	Belongs to the peptidase S41A family
MM326_16010	COG3409	Peptidoglycan-binding domain 1 protein
MM326_16015	COG0739	heme binding
MM326_16020	COG2177	Part of the ABC transporter FtsEX involved in
MM326_16025	COG2884	Cell division ATP-binding protein ftsE
MM326_16030	COG2010	Cytochrome c
MM326_16040	COG0653	protein targeting
MM326_16045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MM326_16050	COG1278	Cold shock
MM326_16065	COG1516	flagellar protein fliS
MM326_16070	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MM326_16080	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MM326_16085	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MM326_16090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MM326_16095	COG4786	Flagellar basal body rod
MM326_16095	COG1256	bacterial-type flagellum assembly
MM326_16120	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MM326_16125	COG1307	EDD domain protein, DegV family
MM326_16140	COG1739	Uncharacterized protein family UPF0029
MM326_16145	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MM326_16150	COG2860	membrane
MM326_16165	COG0601	transmembrane transport
MM326_16170	COG4608	Belongs to the ABC transporter superfamily
MM326_16180	COG1522	sequence-specific DNA binding
MM326_16190	COG4193	domain, Protein
MM326_16200	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MM326_16200	COG1215	transferase activity, transferring glycosyl groups
MM326_16205	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MM326_16215	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MM326_16220	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MM326_16240	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MM326_16245	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MM326_16250	COG4112	unkown
MM326_16260	COG1388	LysM domain
MM326_16260	COG3858	chitin binding
MM326_16290	COG1131	(ABC) transporter
MM326_16300	COG1959	2 iron, 2 sulfur cluster binding
MM326_16305	COG1408	metallophosphoesterase
MM326_16315	COG0561	phosphatase activity
MM326_16320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MM326_16350	COG3275	phosphorelay sensor kinase activity
MM326_16355	COG3279	Response regulator of the LytR AlgR family
MM326_16360	COG1966	Carbon starvation protein
MM326_16365	COG3961	Belongs to the TPP enzyme family
MM326_16370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MM326_16370	COG0519	Catalyzes the synthesis of GMP from XMP
MM326_16375	COG1305	Transglutaminase-like
MM326_16380	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
MM326_16385	COG0714	Associated with various cellular activities
MM326_16395	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MM326_16410	COG0768	penicillin binding
MM326_16415	COG0778	Nitroreductase
MM326_16420	COG1126	abc transporter atp-binding protein
MM326_16425	COG0765	amino acid transport
MM326_16430	COG0765	amino acid transport
MM326_16435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM326_16445	COG0463	Glycosyl transferase, family 2
MM326_16455	COG4485	Bacterial membrane protein, YfhO
MM326_16475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MM326_16480	COG2427	Protein of unknown function (DUF1641)
MM326_16485	COG3383	formate dehydrogenase (NAD+) activity
MM326_16490	COG2116	formate transmembrane transporter activity
MM326_16495	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MM326_16500	COG0314	molybdopterin synthase activity
MM326_16505	COG1763	Mo-molybdopterin cofactor biosynthetic process
MM326_16510	COG0303	'Molybdopterin
MM326_16515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MM326_16520	COG0521	Mo-molybdopterin cofactor biosynthetic process
MM326_16525	COG0746	molybdenum cofactor guanylyltransferase activity
MM326_16530	COG0315	cyclic pyranopterin monophosphate synthase activity
MM326_16535	COG2368	4-hydroxyphenylacetate
MM326_16540	COG2267	carboxylic ester hydrolase activity
MM326_16545	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MM326_16555	COG0459	protein refolding
MM326_16560	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MM326_16565	COG1266	CAAX protease self-immunity
MM326_16580	COG1174	glycine betaine transport
MM326_16585	COG1125	glycine betaine transport
MM326_16585	COG0517	IMP dehydrogenase activity
MM326_16595	COG0805	protein transport
MM326_16600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MM326_16605	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MM326_16610	COG0488	(ABC) transporter
MM326_16615	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MM326_16620	COG0456	acetyltransferase
MM326_16625	COG1214	PFAM Peptidase M22, glycoprotease
MM326_16630	COG0802	atpase or kinase
MM326_16635	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MM326_16655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MM326_16660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MM326_16665	COG1285	pathogenesis
MM326_16670	COG0586	Pfam SNARE associated Golgi protein
MM326_16765	COG3091	SprT-like family
MM326_16775	COG2183	response to ionizing radiation
MM326_16785	COG1191	sigma factor activity
MM326_16790	COG2172	sigma factor antagonist activity
MM326_16795	COG1366	Belongs to the anti-sigma-factor antagonist family
MM326_16800	COG2208	phosphoserine phosphatase activity
MM326_16805	COG2172	sigma factor antagonist activity
MM326_16810	COG1366	Belongs to the anti-sigma-factor antagonist family
MM326_16815	COG1366	Belongs to the anti-sigma-factor antagonist family
MM326_16820	COG2337	Toxic component of a toxin-antitoxin (TA) module
MM326_16825	COG0864	Transcriptional regulator
MM326_16830	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MM326_16835	COG0736	holo-[acyl-carrier-protein] synthase activity
MM326_16840	COG0705	Rhomboid family
MM326_16850	COG1368	sulfuric ester hydrolase activity
MM326_16855	COG1876	peptidase activity
MM326_16865	COG5578	integral membrane protein
MM326_16875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MM326_16885	COG0673	inositol 2-dehydrogenase activity
MM326_16890	COG1082	Xylose isomerase domain protein TIM barrel
MM326_16895	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_16905	COG1320	monovalent cation:proton antiporter activity
MM326_16910	COG2212	antiporter activity
MM326_16915	COG1863	multisubunit Na H antiporter MnhE subunit
MM326_16920	COG0651	ATP synthesis coupled electron transport
MM326_16925	COG1006	Multisubunit Na H antiporter MnhC subunit
MM326_16930	COG2111	Na H antiporter
MM326_16935	COG2111	Na H antiporter
MM326_16935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MM326_16940	COG2205	protein histidine kinase activity
MM326_16950	COG2514	catechol 2,3-dioxygenase activity
MM326_16955	COG1733	regulation of RNA biosynthetic process
MM326_16970	COG4608	Belongs to the ABC transporter superfamily
MM326_16975	COG0791	NLP P60 protein
MM326_16980	COG1619	proteins homologs of microcin C7 resistance protein MccF
MM326_16985	COG4166	transmembrane transport
MM326_16990	COG0444	Belongs to the ABC transporter superfamily
MM326_16995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MM326_17000	COG0601	transmembrane transport
MM326_17005	COG2362	D-Aminopeptidase
MM326_17010	COG2962	Rard protein
MM326_17015	COG2706	6-phosphogluconolactonase activity
MM326_17020	COG0686	Belongs to the AlaDH PNT family
MM326_17025	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MM326_17025	COG2508	Transcriptional regulator
MM326_17030	COG0415	Belongs to the DNA photolyase family
MM326_17040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MM326_17045	COG0531	amino acid
MM326_17070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MM326_17075	COG0596	Alpha beta hydrolase
MM326_17080	COG0861	Integral membrane protein TerC family
MM326_17085	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MM326_17105	COG1404	Belongs to the peptidase S8 family
MM326_17110	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MM326_17115	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MM326_17120	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MM326_17125	COG3639	organic phosphonate transmembrane transporter activity
MM326_17130	COG3639	organic phosphonate transmembrane transporter activity
MM326_17135	COG0604	alcohol dehydrogenase
MM326_17145	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MM326_17165	COG0024	Methionine aminopeptidase
MM326_17175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MM326_17190	COG1846	Transcriptional regulator
MM326_17200	COG2239	Acts as a magnesium transporter
MM326_17205	COG1304	FMN binding
MM326_17215	COG1917	Cupin 2, conserved barrel domain protein
MM326_17215	COG4977	sequence-specific DNA binding
MM326_17220	COG1486	melibiose metabolic process
MM326_17235	COG0395	ABC-type sugar transport system, permease component
MM326_17240	COG4209	transmembrane transport
MM326_17245	COG4753	response regulator
MM326_17245	COG2207	Transcriptional regulator
MM326_17250	COG2972	Histidine kinase
MM326_17255	COG1653	transport
MM326_17265	COG2195	Cleaves the N-terminal amino acid of tripeptides
MM326_17270	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MM326_17275	COG1136	(ABC) transporter
MM326_17280	COG0577	efflux transmembrane transporter activity
MM326_17295	COG0395	ABC-type sugar transport system, permease component
MM326_17310	COG2207	Transcriptional regulator
MM326_17320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MM326_17330	COG0183	Belongs to the thiolase family
MM326_17335	COG1250	3-hydroxyacyl-CoA dehydrogenase
MM326_17340	COG0045	succinate-CoA ligase (ADP-forming) activity
MM326_17340	COG1042	CoA-binding domain protein
MM326_17340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM326_17345	COG1960	acyl-CoA dehydrogenase activity
MM326_17355	COG1012	belongs to the aldehyde dehydrogenase family
MM326_17360	COG1063	alcohol dehydrogenase
MM326_17370	COG2271	Major facilitator Superfamily
MM326_17375	COG0431	NADPH-dependent FMN reductase
MM326_17390	COG1012	belongs to the aldehyde dehydrogenase family
MM326_17395	COG1024	Enoyl-CoA hydratase
MM326_17400	COG3829	transcription factor binding
MM326_17400	COG3290	protein histidine kinase activity
MM326_17405	COG0028	Belongs to the TPP enzyme family
MM326_17425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MM326_17430	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MM326_17440	COG2258	MOSC domain
MM326_17465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MM326_17475	COG2084	Dehydrogenase
MM326_17485	COG1737	Transcriptional regulator
MM326_17495	COG0697	spore germination
MM326_17520	COG0577	efflux transmembrane transporter activity
MM326_17520	COG1136	(ABC) transporter
MM326_17525	COG0577	efflux transmembrane transporter activity
MM326_17525	COG1136	(ABC) transporter
MM326_17530	COG5002	protein histidine kinase activity
MM326_17530	COG3850	Histidine kinase
MM326_17535	COG0745	RESPONSE REGULATOR receiver
MM326_17555	COG1309	transcriptional regulator
MM326_17560	COG0477	Major facilitator Superfamily
MM326_17580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MM326_17590	COG2340	Cysteine-rich secretory protein family
MM326_17610	COG1376	ErfK ybiS ycfS ynhG family protein
MM326_17660	COG2217	Heavy metal translocating P-type atpase
MM326_17665	COG1113	amino acid transport
MM326_17705	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_17735	COG5504	Zn-dependent protease
MM326_17760	COG3842	ATPase activity
MM326_17765	COG0395	ABC-type sugar transport system, permease component
MM326_17770	COG1175	transmembrane transport
MM326_17780	COG0385	Bile acid
MM326_17790	COG1686	Belongs to the peptidase S11 family
MM326_17795	COG0716	FMN binding
MM326_17805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MM326_17805	COG0551	DNA topoisomerase type I activity
MM326_17815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM326_17830	COG3192	ethanolamine utilization protein
MM326_17835	COG1609	Transcriptional regulator
MM326_17845	COG1621	beta-fructofuranosidase activity
MM326_17855	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MM326_17860	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_17865	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MM326_17865	COG0512	Glutamine amidotransferase of anthranilate synthase
MM326_17875	COG3069	C4-dicarboxylate transmembrane transporter activity
MM326_17880	COG0372	Belongs to the citrate synthase family
MM326_17885	COG0583	DNA-binding transcription factor activity
MM326_17920	COG2897	thiosulfate sulfurtransferase activity
MM326_17925	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_17930	COG0693	protein deglycase activity
MM326_17945	COG1131	(ABC) transporter
MM326_17985	COG1302	Protein conserved in bacteria
MM326_18010	COG0667	Aldo Keto reductase
MM326_18020	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MM326_18035	COG2226	methyltransferase
MM326_18040	COG0456	acetyltransferase
MM326_18045	COG0248	Ppx GppA phosphatase
MM326_18050	COG3639	organic phosphonate transmembrane transporter activity
MM326_18055	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MM326_18065	COG2814	Major facilitator Superfamily
MM326_18080	COG0456	acetyltransferase
MM326_18085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MM326_18110	COG1132	(ABC) transporter
MM326_18115	COG1132	(ABC) transporter
MM326_18155	COG0300	oxidoreductase activity
MM326_18160	COG1280	lysine exporter protein (LysE YggA)
MM326_18165	COG1690	Belongs to the RtcB family
MM326_18170	COG3340	Belongs to the peptidase S51 family
MM326_18175	COG0346	lactoylglutathione lyase activity
MM326_18230	COG2814	Major facilitator Superfamily
MM326_18245	COG2357	RelA SpoT domain protein
MM326_18275	COG2226	methyltransferase
MM326_18280	COG1366	Belongs to the anti-sigma-factor antagonist family
MM326_18290	COG1942	4-Oxalocrotonate Tautomerase
MM326_18300	COG0583	DNA-binding transcription factor activity
MM326_18315	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MM326_18320	COG0583	DNA-binding transcription factor activity
MM326_18325	COG1063	alcohol dehydrogenase
MM326_18335	COG2261	transglycosylase associated protein
MM326_18340	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MM326_18360	COG2388	GCN5-related N-acetyl-transferase
MM326_18370	COG1335	isochorismatase
MM326_18395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MM326_18415	COG0640	Transcriptional regulator
MM326_18430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MM326_18445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MM326_18450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MM326_18490	COG1929	Belongs to the glycerate kinase type-1 family
MM326_18495	COG3835	regulator
MM326_18500	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_18505	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MM326_18515	COG2197	response regulator
MM326_18520	COG2203	Gaf domain
MM326_18520	COG4585	Histidine kinase
MM326_18525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MM326_18530	COG3443	Belongs to the bacterial solute-binding protein 9 family
MM326_18535	COG0803	Belongs to the bacterial solute-binding protein 9 family
MM326_18540	COG1121	(ABC) transporter
MM326_18545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MM326_18570	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_18575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MM326_18580	COG1850	ribulose-bisphosphate carboxylase activity
MM326_18590	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MM326_18590	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MM326_18595	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MM326_18600	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MM326_18625	COG1396	sequence-specific DNA binding
MM326_18630	COG1396	sequence-specific DNA binding
MM326_18650	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MM326_18655	COG2843	Capsule synthesis protein
MM326_18670	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MM326_18670	COG0662	Cupin 2, conserved barrel domain protein
MM326_18690	COG0438	transferase activity, transferring glycosyl groups
MM326_18695	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MM326_18700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MM326_18710	COG4978	Transcriptional regulator
MM326_18710	COG0789	Transcriptional regulator
MM326_18715	COG2249	NAD(P)H dehydrogenase (quinone) activity
MM326_18725	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MM326_18745	COG3177	Filamentation induced by cAMP protein fic
MM326_18795	COG1595	DNA-templated transcription, initiation
MM326_18870	COG5632	N-Acetylmuramoyl-L-alanine amidase
MM326_18870	COG3409	Peptidoglycan-binding domain 1 protein
MM326_18880	COG4824	toxin secretion phage lysis holin
MM326_18900	COG1396	sequence-specific DNA binding
MM326_18920	COG0697	spore germination
MM326_18965	COG1063	alcohol dehydrogenase
MM326_18970	COG4978	Transcriptional regulator
MM326_18970	COG0789	Transcriptional regulator
MM326_18975	COG1266	CAAX protease self-immunity
MM326_19010	COG2202	Pas domain
MM326_19010	COG1366	Belongs to the anti-sigma-factor antagonist family
MM326_19015	COG1511	domain protein
MM326_19015	COG1511	domain protein
MM326_19065	COG0653	protein targeting
MM326_19100	COG0318	PFAM AMP-dependent synthetase and ligase
MM326_19115	COG4565	transcriptional regulatory protein
MM326_19120	COG3290	protein histidine kinase activity
MM326_19125	COG0671	phosphoesterase, PA-phosphatase related
MM326_19145	COG0439	Biotin carboxylase
MM326_19160	COG0531	amino acid
MM326_19170	COG1366	Belongs to the anti-sigma-factor antagonist family
MM326_19175	COG3620	sequence-specific DNA binding
MM326_19185	COG2207	Transcriptional regulator
MM326_19190	COG1388	LysM domain
MM326_19200	COG0753	catalase activity
MM326_19230	COG0569	domain protein
MM326_19235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MM326_19240	COG0628	permease
MM326_19250	COG2755	lipolytic protein G-D-S-L family
MM326_19305	COG2182	Extracellular solute-binding protein
MM326_19310	COG1175	transmembrane transport
MM326_19315	COG3833	ABC-type maltose transport systems, permease component
MM326_19330	COG2814	Major facilitator Superfamily
MM326_19355	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MM326_19355	COG0165	Argininosuccinate lyase
MM326_19370	COG3250	beta-galactosidase activity
MM326_19385	COG1175	transmembrane transport
MM326_19390	COG0395	ABC-type sugar transport system, permease component
MM326_19395	COG1657	PFAM Prenyltransferase squalene oxidase
MM326_19415	COG3181	Tripartite tricarboxylate transporter family receptor
MM326_19420	COG4565	transcriptional regulatory protein
MM326_19425	COG3290	protein histidine kinase activity
MM326_19430	COG0318	PFAM AMP-dependent synthetase and ligase
MM326_19435	COG4464	protein tyrosine phosphatase activity
MM326_19440	COG0489	protein tyrosine kinase activity
MM326_19445	COG3944	biosynthesis protein
MM326_19450	COG1316	TRANSCRIPTIONal
MM326_19455	COG2076	Multidrug Resistance protein
MM326_19460	COG2076	Multidrug Resistance protein
MM326_19470	COG0702	epimerase
MM326_19475	COG0772	Belongs to the SEDS family
MM326_19480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MM326_19495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MM326_19500	COG0791	NLP P60 protein
MM326_19500	COG1388	LysM domain
MM326_19505	COG0010	Belongs to the arginase family
MM326_19515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MM326_19525	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MM326_19550	COG4786	Flagellar basal body rod
MM326_19555	COG4786	Flagellar basal body rod
MM326_19560	COG1077	Cell shape determining protein MreB Mrl
MM326_19565	COG1609	Transcriptional regulator
MM326_19570	COG0739	heme binding
MM326_19575	COG2385	sporulation resulting in formation of a cellular spore
MM326_19580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MM326_19595	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MM326_19600	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MM326_19605	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MM326_19610	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MM326_19615	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MM326_19620	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MM326_19625	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MM326_19630	COG0356	it plays a direct role in the translocation of protons across the membrane
MM326_19650	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MM326_19655	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MM326_19660	COG4475	Protein of unknown function (DUF436)
MM326_19665	COG0698	ribose 5-phosphate isomerase
MM326_19680	COG1971	Probably functions as a manganese efflux pump
MM326_19690	COG0009	L-threonylcarbamoyladenylate synthase
MM326_19710	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MM326_19715	COG0446	pyridine nucleotide-disulphide oxidoreductase
MM326_19725	COG1435	thymidine kinase activity
MM326_19730	COG0254	rRNA binding
MM326_19735	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MM326_19740	COG1494	fructose-1,6-bisphosphatase
MM326_19745	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MM326_19750	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MM326_19755	COG0191	fructose-bisphosphate aldolase activity
MM326_19770	COG1305	Transglutaminase-like
MM326_19775	COG0504	CTP synthase activity
MM326_19780	COG3343	RNA polymerase activity
MM326_19790	COG1960	acyl-CoA dehydrogenase activity
MM326_19795	COG1250	3-hydroxyacyl-CoA dehydrogenase
MM326_19800	COG0183	Belongs to the thiolase family
MM326_19805	COG0247	lactate metabolic process
MM326_19805	COG2181	nitrate reductase activity
MM326_19810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MM326_19815	COG2839	Protein conserved in bacteria
MM326_19820	COG0018	arginyl-trna synthetase
MM326_19830	COG0010	Belongs to the arginase family
MM326_19835	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MM326_19840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MM326_19845	COG0456	acetyltransferase
MM326_19860	COG1164	Oligoendopeptidase f
MM326_19880	COG1942	4-Oxalocrotonate Tautomerase
MM326_19890	COG3465	dGTPase activity
MM326_19895	COG1078	dGTPase activity
MM326_19900	COG1301	dicarboxylic acid transport
MM326_19905	COG0095	Lipoate-protein ligase
MM326_19910	COG0280	phosphate acetyltransferase
MM326_19915	COG1024	Enoyl-CoA hydratase
MM326_19920	COG3253	May function as heme-dependent peroxidase
MM326_19925	COG0706	membrane insertase activity
MM326_19935	COG1668	transmembrane transport
MM326_19940	COG4152	abc transporter atp-binding protein
MM326_19945	COG3773	Cell wall hydrolase
MM326_19955	COG2363	Small membrane protein
MM326_19960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MM326_19960	COG3153	acetyltransferase
MM326_19980	COG0004	ammonium transporteR
MM326_19985	COG5577	PFAM Coat F domain
MM326_19995	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MM326_20000	COG3314	Sporulation integral membrane protein YlbJ
MM326_20005	COG0840	transmembrane signaling receptor activity
MM326_20005	COG3290	protein histidine kinase activity
MM326_20010	COG0351	phosphomethylpyrimidine kinase
MM326_20015	COG2986	histidine ammonia-lyase
MM326_20040	COG0513	Belongs to the DEAD box helicase family
MM326_20055	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MM326_20060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MM326_20060	COG0723	plastoquinol--plastocyanin reductase activity
MM326_20090	COG1785	Belongs to the alkaline phosphatase family
MM326_20095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MM326_20095	COG0551	DNA topoisomerase type I activity
MM326_20100	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MM326_20110	COG2814	Major facilitator Superfamily
MM326_20120	COG5582	Belongs to the UPF0302 family
MM326_20125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MM326_20130	COG1321	iron dependent repressor
MM326_20130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MM326_20135	COG1121	(ABC) transporter
MM326_20140	COG0803	Belongs to the bacterial solute-binding protein 9 family
MM326_20145	COG0561	phosphatase activity
MM326_20150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MM326_20175	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MM326_20180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MM326_20185	COG2814	Major facilitator Superfamily
MM326_20215	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM326_20220	COG0753	catalase activity
MM326_20225	COG1132	(ABC) transporter
MM326_20235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MM326_20240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MM326_20245	COG2323	membrane
MM326_20250	COG1597	lipid kinase activity
MM326_20255	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MM326_20260	COG1028	Short-chain dehydrogenase reductase Sdr
MM326_20265	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MM326_20265	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MM326_20275	COG0577	efflux transmembrane transporter activity
MM326_20275	COG1136	(ABC) transporter
MM326_20300	COG1114	Component of the transport system for branched-chain amino acids
MM326_20305	COG2154	pterin-4-alpha-carbinolamine dehydratase
MM326_20320	COG5002	protein histidine kinase activity
MM326_20325	COG0745	RESPONSE REGULATOR receiver
MM326_20335	COG2807	transmembrane transport
MM326_20340	COG1012	belongs to the aldehyde dehydrogenase family
MM326_20345	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MM326_20350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MM326_20360	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MM326_20370	COG0471	metal ion transport
MM326_20375	COG4565	transcriptional regulatory protein
MM326_20380	COG3290	protein histidine kinase activity
MM326_20425	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MM326_20435	COG1215	transferase activity, transferring glycosyl groups
MM326_20440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MM326_20445	COG0668	transmembrane transport
MM326_20450	COG1366	Belongs to the anti-sigma-factor antagonist family
MM326_20455	COG0813	purine-nucleoside phosphorylase activity
MM326_20460	COG0346	lactoylglutathione lyase activity
MM326_20475	COG0577	efflux transmembrane transporter activity
MM326_20480	COG1136	(ABC) transporter
MM326_20485	COG0642	Histidine kinase
MM326_20490	COG0745	RESPONSE REGULATOR receiver
MM326_20495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MM326_20500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MM326_20515	COG1657	PFAM Prenyltransferase squalene oxidase
MM326_20525	COG4149	molybdate abc transporter
MM326_20530	COG0725	ABC transporter, periplasmic molybdate-binding protein
MM326_20535	COG1910	domain protein
MM326_20565	COG0640	Transcriptional regulator
MM326_20580	COG1033	growth of symbiont in host cell
MM326_20580	COG2409	Drug exporters of the RND superfamily
MM326_20635	COG0579	oxidoreductase
MM326_20650	COG1164	Oligoendopeptidase f
MM326_20665	COG3829	transcription factor binding
MM326_20665	COG3290	protein histidine kinase activity
MM326_20670	COG1454	alcohol dehydrogenase
MM326_20675	COG2610	gluconate transmembrane transporter activity
MM326_20700	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MM326_20710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MM326_20715	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MM326_20720	COG4853	Protein conserved in bacteria
MM326_20730	COG5002	protein histidine kinase activity
MM326_20735	COG0745	RESPONSE REGULATOR receiver
MM326_20765	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MM326_20770	COG0305	Participates in initiation and elongation during chromosome replication
MM326_20775	COG0359	binds to the 23S rRNA
MM326_20780	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MM326_20790	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MM326_20795	COG0629	single-stranded DNA binding
MM326_20800	COG0360	Binds together with S18 to 16S ribosomal RNA
MM326_20805	COG0012	GTP binding
MM326_20810	COG4481	Protein conserved in bacteria
MM326_20815	COG3949	Membrane
MM326_20825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MM326_20830	COG1475	DNA binding
MM326_20835	COG1192	Involved in chromosome partitioning
MM326_20840	COG1475	DNA binding
MM326_20845	COG0357	Ribosomal RNA small subunit methyltransferase G
MM326_20850	COG0445	tRNA wobble uridine modification
MM326_20855	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MM326_20860	COG1847	R3H domain protein
MM326_20865	COG0706	membrane insertase activity
MM326_20870	COG0594	ribonuclease P activity
MM326_20875	COG0230	Belongs to the bacterial ribosomal protein bL34 family