locus-tag	class	description
LVQ62_00025	COG2755	lipolytic protein G-D-S-L family
LVQ62_00030	COG0183	Belongs to the thiolase family
LVQ62_00055	COG4585	Histidine kinase
LVQ62_00060	COG1131	(ABC) transporter
LVQ62_00090	COG0148	phosphopyruvate hydratase activity
LVQ62_00115	COG0193	aminoacyl-tRNA hydrolase activity
LVQ62_00120	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LVQ62_00125	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LVQ62_00130	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LVQ62_00150	COG4106	trans-aconitate 2-methyltransferase activity
LVQ62_00155	COG1846	Transcriptional regulator
LVQ62_00160	COG0488	(ABC) transporter
LVQ62_00165	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LVQ62_00170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LVQ62_00175	COG0084	hydrolase, TatD family'
LVQ62_00180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LVQ62_00230	COG4221	oxidoreductase activity
LVQ62_00250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LVQ62_00255	COG0521	Mo-molybdopterin cofactor biosynthetic process
LVQ62_00260	COG0315	cyclic pyranopterin monophosphate synthase activity
LVQ62_00270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LVQ62_00275	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LVQ62_00290	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LVQ62_00350	COG0318	PFAM AMP-dependent synthetase and ligase
LVQ62_00365	COG1960	acyl-CoA dehydrogenase activity
LVQ62_00375	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_00385	COG0183	Belongs to the thiolase family
LVQ62_00395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LVQ62_00400	COG1349	DNA-binding transcription factor activity
LVQ62_00410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LVQ62_00415	COG4214	carbohydrate transport
LVQ62_00430	COG0406	alpha-ribazole phosphatase activity
LVQ62_00435	COG1070	Carbohydrate kinase
LVQ62_00455	COG0791	NLP P60 protein
LVQ62_00455	COG1388	LysM domain
LVQ62_00455	COG3103	Sh3 type 3 domain protein
LVQ62_00465	COG0259	pyridoxamine-phosphate oxidase activity
LVQ62_00475	COG0701	Predicted permease
LVQ62_00500	COG0745	RESPONSE REGULATOR receiver
LVQ62_00505	COG2205	protein histidine kinase activity
LVQ62_00510	COG2205	protein histidine kinase activity
LVQ62_00515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LVQ62_00525	COG1902	pentaerythritol trinitrate reductase activity
LVQ62_00525	COG0446	pyridine nucleotide-disulphide oxidoreductase
LVQ62_00535	COG1595	DNA-templated transcription, initiation
LVQ62_00550	COG3158	transport of potassium into the cell
LVQ62_00560	COG0459	protein refolding
LVQ62_00605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LVQ62_00630	COG1960	acyl-CoA dehydrogenase activity
LVQ62_00640	COG2017	converts alpha-aldose to the beta-anomer
LVQ62_00645	COG0318	PFAM AMP-dependent synthetase and ligase
LVQ62_00655	COG3590	peptidase
LVQ62_00690	COG1061	Type III restriction enzyme res subunit
LVQ62_00700	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LVQ62_00720	COG1278	Cold shock
LVQ62_00735	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LVQ62_00745	COG4948	Mandelate Racemase Muconate Lactonizing
LVQ62_00765	COG1575	Belongs to the MenA family. Type 1 subfamily
LVQ62_00805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LVQ62_00815	COG0785	Cytochrome C biogenesis protein
LVQ62_00825	COG0406	alpha-ribazole phosphatase activity
LVQ62_00830	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LVQ62_00840	COG0113	porphobilinogen synthase activity
LVQ62_00845	COG1648	precorrin-2 dehydrogenase activity
LVQ62_00845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LVQ62_00850	COG0181	hydroxymethylbilane synthase activity
LVQ62_00855	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LVQ62_00860	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LVQ62_00890	COG0123	including yeast histone deacetylase and acetoin utilization protein
LVQ62_00900	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LVQ62_00905	COG0506	proline dehydrogenase activity
LVQ62_00910	COG1305	Transglutaminase-like
LVQ62_00935	COG2318	DinB family
LVQ62_00940	COG1285	pathogenesis
LVQ62_00950	COG1082	Xylose isomerase domain protein TIM barrel
LVQ62_00955	COG0248	Ppx GppA phosphatase
LVQ62_00965	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LVQ62_00970	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LVQ62_00980	COG3265	gluconokinase activity
LVQ62_01005	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LVQ62_01025	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LVQ62_01030	COG1793	dna ligase
LVQ62_01030	COG3285	dna ligase
LVQ62_01060	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LVQ62_01095	COG0649	NAD binding
LVQ62_01105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LVQ62_01110	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LVQ62_01115	COG0302	gtp cyclohydrolase
LVQ62_01120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LVQ62_01130	COG0037	tRNA processing
LVQ62_01140	COG2272	Belongs to the type-B carboxylesterase lipase family
LVQ62_01150	COG2027	D-alanyl-D-alanine carboxypeptidase
LVQ62_01155	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LVQ62_01165	COG0596	Alpha beta hydrolase
LVQ62_01185	COG0513	Belongs to the DEAD box helicase family
LVQ62_01200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LVQ62_01230	COG1609	Transcriptional regulator
LVQ62_01275	COG1074	ATP-dependent DNA helicase activity
LVQ62_01360	COG0470	DNA polymerase III
LVQ62_01365	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LVQ62_01380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LVQ62_01380	COG1754	DNA topoisomerase type I activity
LVQ62_01385	COG2890	protein-(glutamine-N5) methyltransferase activity
LVQ62_01390	COG1366	Belongs to the anti-sigma-factor antagonist family
LVQ62_01395	COG1111	helicase
LVQ62_01395	COG1205	dead DEAH box helicase
LVQ62_01450	COG3263	regulation of cellular component size
LVQ62_01475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LVQ62_01520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LVQ62_01565	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LVQ62_01575	COG1715	Restriction endonuclease
LVQ62_01580	COG3311	Transcriptional regulator
LVQ62_01585	COG1569	PIN domain
LVQ62_01590	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LVQ62_01635	COG2268	Band 7 protein
LVQ62_01640	COG1960	acyl-CoA dehydrogenase activity
LVQ62_01645	COG1126	abc transporter atp-binding protein
LVQ62_01650	COG0765	amino acid transport
LVQ62_01680	COG0577	efflux transmembrane transporter activity
LVQ62_01680	COG1136	(ABC) transporter
LVQ62_01690	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LVQ62_01715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LVQ62_01725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LVQ62_01730	COG0798	PFAM Bile acid sodium symporter
LVQ62_01735	COG2226	methyltransferase
LVQ62_01740	COG0640	Transcriptional regulator
LVQ62_01785	COG0405	Gamma-glutamyltransferase
LVQ62_01790	COG0656	L-ascorbic acid biosynthetic process
LVQ62_01830	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LVQ62_01835	COG0154	amidase activity
LVQ62_01845	COG0433	COG0433 Predicted ATPase
LVQ62_01870	COG0477	Major facilitator Superfamily
LVQ62_01875	COG0531	amino acid
LVQ62_01885	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LVQ62_01900	COG0242	peptide deformylase activity
LVQ62_01955	COG0598	Magnesium transport protein CorA
LVQ62_01975	COG0406	alpha-ribazole phosphatase activity
LVQ62_01980	COG1492	cobalamin metabolic process
LVQ62_01990	COG3844	kynureninase activity
LVQ62_02000	COG0778	Nitroreductase
LVQ62_02060	COG1797	cobyrinic acid a,c-diamide synthase activity
LVQ62_02070	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LVQ62_02090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LVQ62_02095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LVQ62_02100	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LVQ62_02110	COG2267	carboxylic ester hydrolase activity
LVQ62_02120	COG0745	RESPONSE REGULATOR receiver
LVQ62_02125	COG2205	protein histidine kinase activity
LVQ62_02135	COG1349	DNA-binding transcription factor activity
LVQ62_02140	COG0149	triose-phosphate isomerase activity
LVQ62_02145	COG0698	ribose 5-phosphate isomerase
LVQ62_02160	COG1172	Belongs to the binding-protein-dependent transport system permease family
LVQ62_02185	COG1316	TRANSCRIPTIONal
LVQ62_02190	COG1278	Cold shock
LVQ62_02200	COG2197	response regulator
LVQ62_02205	COG4585	Histidine kinase
LVQ62_02215	COG1131	(ABC) transporter
LVQ62_02245	COG0776	regulation of translation
LVQ62_02255	COG2197	response regulator
LVQ62_02270	COG0667	Aldo Keto reductase
LVQ62_02280	COG1595	DNA-templated transcription, initiation
LVQ62_02290	COG1045	serine acetyltransferase
LVQ62_02300	COG0247	lactate metabolic process
LVQ62_02300	COG2181	nitrate reductase activity
LVQ62_02340	COG0717	Belongs to the dCTP deaminase family
LVQ62_02350	COG4585	Histidine kinase
LVQ62_02370	COG1881	PFAM PEBP family protein
LVQ62_02385	COG3191	aminopeptidase activity
LVQ62_02390	COG1960	acyl-CoA dehydrogenase activity
LVQ62_02395	COG0247	lactate metabolic process
LVQ62_02400	COG1139	Iron-sulfur cluster binding protein
LVQ62_02405	COG1556	Lactate utilization protein
LVQ62_02440	COG2814	Major facilitator Superfamily
LVQ62_02445	COG0247	lactate metabolic process
LVQ62_02445	COG0277	FAD linked oxidase domain protein
LVQ62_02450	COG0508	dehydrogenase complex catalyzes the overall conversion of
LVQ62_02455	COG0022	dehydrogenase e1 component
LVQ62_02470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LVQ62_02530	COG0640	Transcriptional regulator
LVQ62_02580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LVQ62_02585	COG0018	arginyl-trna synthetase
LVQ62_02595	COG1968	undecaprenyl-diphosphatase activity
LVQ62_02615	COG2116	formate transmembrane transporter activity
LVQ62_02620	COG0596	Alpha beta hydrolase
LVQ62_02630	COG0488	(ABC) transporter
LVQ62_02640	COG0477	Major facilitator Superfamily
LVQ62_02665	COG1309	transcriptional regulator
LVQ62_02670	COG0702	epimerase
LVQ62_02680	COG2226	methyltransferase
LVQ62_02705	COG0582	viral genome integration into host DNA
LVQ62_02725	COG1271	oxidase subunit
LVQ62_02730	COG1294	oxidase, subunit
LVQ62_02735	COG4988	ABC transporter
LVQ62_02750	COG0501	Belongs to the peptidase M48B family
LVQ62_02755	COG2409	Drug exporters of the RND superfamily
LVQ62_02770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LVQ62_02775	COG0156	8-amino-7-oxononanoate synthase activity
LVQ62_02780	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LVQ62_02805	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LVQ62_02810	COG1937	Protein conserved in bacteria
LVQ62_02830	COG4214	carbohydrate transport
LVQ62_02845	COG2115	Belongs to the xylose isomerase family
LVQ62_02865	COG1309	transcriptional regulator
LVQ62_02885	COG0561	phosphatase activity
LVQ62_02900	COG1597	lipid kinase activity
LVQ62_02950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LVQ62_02965	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LVQ62_02965	COG1918	ferrous iron import across plasma membrane
LVQ62_02970	COG0531	amino acid
LVQ62_02980	COG0114	fumarate hydratase activity
LVQ62_02985	COG3046	protein related to deoxyribodipyrimidine photolyase
LVQ62_02990	COG0500	methyltransferase
LVQ62_02995	COG0667	Aldo Keto reductase
LVQ62_03000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LVQ62_03005	COG1584	GPR1 FUN34 yaaH family protein
LVQ62_03015	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LVQ62_03020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LVQ62_03070	COG1136	(ABC) transporter
LVQ62_03070	COG0577	efflux transmembrane transporter activity
LVQ62_03085	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LVQ62_03090	COG0425	Belongs to the sulfur carrier protein TusA family
LVQ62_03090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LVQ62_03100	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LVQ62_03110	COG2814	Major facilitator Superfamily
LVQ62_03115	COG1846	Transcriptional regulator
LVQ62_03125	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LVQ62_03155	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LVQ62_03180	COG0596	Alpha beta hydrolase
LVQ62_03180	COG0508	dehydrogenase complex catalyzes the overall conversion of
LVQ62_03205	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LVQ62_03210	COG1063	alcohol dehydrogenase
LVQ62_03240	COG0154	amidase activity
LVQ62_03280	COG2310	stress, protein
LVQ62_03295	COG0583	DNA-binding transcription factor activity
LVQ62_03310	COG0431	NADPH-dependent FMN reductase
LVQ62_03315	COG3795	YCII-related domain
LVQ62_03360	COG3835	regulator
LVQ62_03425	COG1012	belongs to the aldehyde dehydrogenase family
LVQ62_03450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LVQ62_03475	COG0438	transferase activity, transferring glycosyl groups
LVQ62_03490	COG1216	Glycosyl transferase, family 2
LVQ62_03510	COG0702	epimerase
LVQ62_03515	COG0783	Belongs to the Dps family
LVQ62_03530	COG2376	Dihydroxyacetone kinase
LVQ62_03535	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LVQ62_03540	COG2154	pterin-4-alpha-carbinolamine dehydratase
LVQ62_03555	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_03580	COG1063	alcohol dehydrogenase
LVQ62_03585	COG0156	8-amino-7-oxononanoate synthase activity
LVQ62_03590	COG0477	Major facilitator Superfamily
LVQ62_03615	COG0667	Aldo Keto reductase
LVQ62_03620	COG0531	amino acid
LVQ62_03625	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LVQ62_03635	COG2860	membrane
LVQ62_03655	COG0745	RESPONSE REGULATOR receiver
LVQ62_03660	COG2205	protein histidine kinase activity
LVQ62_03670	COG4656	Part of a membrane complex involved in electron transport
LVQ62_03695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LVQ62_03730	COG0662	Cupin 2, conserved barrel domain protein
LVQ62_03735	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_03770	COG0768	penicillin binding
LVQ62_03775	COG0515	serine threonine protein kinase
LVQ62_03790	COG0515	serine threonine protein kinase
LVQ62_03865	COG0701	Predicted permease
LVQ62_03870	COG2132	Multicopper oxidase
LVQ62_03885	COG1132	(ABC) transporter
LVQ62_03890	COG1215	transferase activity, transferring glycosyl groups
LVQ62_03910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LVQ62_03915	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LVQ62_03945	COG0438	transferase activity, transferring glycosyl groups
LVQ62_03960	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LVQ62_03975	COG4941	Belongs to the sigma-70 factor family
LVQ62_04025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LVQ62_04040	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
LVQ62_04045	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LVQ62_04055	COG0592	DNA-directed DNA polymerase activity
LVQ62_04060	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LVQ62_04065	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LVQ62_04070	COG0594	ribonuclease P activity
LVQ62_04075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LVQ62_04080	COG0706	membrane insertase activity
LVQ62_04090	COG0357	Ribosomal RNA small subunit methyltransferase G
LVQ62_04100	COG1475	DNA binding
LVQ62_04105	COG3118	belongs to the thioredoxin family
LVQ62_04110	COG0492	ferredoxin-NADP+ reductase activity
LVQ62_04130	COG1595	DNA-templated transcription, initiation
LVQ62_04135	COG0515	serine threonine protein kinase
LVQ62_04135	COG2815	serine threonine protein kinase
LVQ62_04150	COG2816	NAD+ diphosphatase activity
LVQ62_04155	COG0617	tRNA 3'-terminal CCA addition
LVQ62_04160	COG2124	cytochrome p450
LVQ62_04165	COG0297	glycogen (starch) synthase activity
LVQ62_04180	COG3795	YCII-related domain
LVQ62_04185	COG4941	Belongs to the sigma-70 factor family
LVQ62_04205	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LVQ62_04215	COG1309	transcriptional regulator
LVQ62_04260	COG1302	Protein conserved in bacteria
LVQ62_04355	COG1260	myo-inositol-1-phosphate synthase
LVQ62_04360	COG1695	Transcriptional regulator
LVQ62_04365	COG1764	response to oxidative stress
LVQ62_04370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LVQ62_04375	COG3665	Urea carboxylase-associated protein
LVQ62_04395	COG0360	Binds together with S18 to 16S ribosomal RNA
LVQ62_04405	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LVQ62_04410	COG0359	binds to the 23S rRNA
LVQ62_04445	COG0791	NLP P60 protein
LVQ62_04445	COG3103	Sh3 type 3 domain protein
LVQ62_04445	COG1388	LysM domain
LVQ62_04450	COG0305	Participates in initiation and elongation during chromosome replication
LVQ62_04480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LVQ62_04510	COG3942	CHAP domain
LVQ62_04510	COG1388	LysM domain
LVQ62_04515	COG0402	S-adenosylhomocysteine deaminase activity
LVQ62_04525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LVQ62_04535	COG2233	PERMEase
LVQ62_04555	COG1414	Transcriptional regulator
LVQ62_04570	COG3622	Belongs to the hyi family
LVQ62_04575	COG2084	Dehydrogenase
LVQ62_04580	COG3960	tartronate-semialdehyde synthase activity
LVQ62_04585	COG1929	Belongs to the glycerate kinase type-1 family
LVQ62_04590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LVQ62_04595	COG4266	Belongs to the allantoicase family
LVQ62_04600	COG1216	Glycosyl transferase, family 2
LVQ62_04625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LVQ62_04630	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LVQ62_04640	COG1396	sequence-specific DNA binding
LVQ62_04660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LVQ62_04690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LVQ62_04700	COG0667	Aldo Keto reductase
LVQ62_04730	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_04730	COG0604	alcohol dehydrogenase
LVQ62_04730	COG3321	synthase
LVQ62_04745	COG0667	Aldo Keto reductase
LVQ62_04760	COG3340	Belongs to the peptidase S51 family
LVQ62_04785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LVQ62_04825	COG0596	Alpha beta hydrolase
LVQ62_04845	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LVQ62_04850	COG4221	oxidoreductase activity
LVQ62_04880	COG1620	l-lactate permease
LVQ62_04885	COG0247	lactate metabolic process
LVQ62_04895	COG0277	FAD linked oxidase domain protein
LVQ62_04900	COG0277	FAD linked oxidase domain protein
LVQ62_04930	COG0438	transferase activity, transferring glycosyl groups
LVQ62_04960	COG0693	protein deglycase activity
LVQ62_04965	COG0531	amino acid
LVQ62_04970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LVQ62_04995	COG1024	Enoyl-CoA hydratase
LVQ62_05000	COG0494	nUDIX hydrolase
LVQ62_05020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LVQ62_05020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LVQ62_05030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LVQ62_05050	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LVQ62_05050	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LVQ62_05070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LVQ62_05090	COG1191	sigma factor activity
LVQ62_05095	COG0318	PFAM AMP-dependent synthetase and ligase
LVQ62_05110	COG0406	alpha-ribazole phosphatase activity
LVQ62_05115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LVQ62_05120	COG2267	carboxylic ester hydrolase activity
LVQ62_05145	COG0494	nUDIX hydrolase
LVQ62_05175	COG2986	histidine ammonia-lyase
LVQ62_05180	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LVQ62_05185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LVQ62_05195	COG1228	amidohydrolase
LVQ62_05240	COG3842	ATPase activity
LVQ62_05275	COG1136	(ABC) transporter
LVQ62_05285	COG0318	PFAM AMP-dependent synthetase and ligase
LVQ62_05310	COG1172	Belongs to the binding-protein-dependent transport system permease family
LVQ62_05315	COG1172	Belongs to the binding-protein-dependent transport system permease family
LVQ62_05320	COG1129	ABC transporter
LVQ62_05325	COG1879	ABC-type sugar transport system periplasmic component
LVQ62_05340	COG3384	dioxygenase
LVQ62_05345	COG1846	Transcriptional regulator
LVQ62_05395	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LVQ62_05445	COG2233	PERMEase
LVQ62_05475	COG0596	Alpha beta hydrolase
LVQ62_05495	COG0443	Heat shock 70 kDa protein
LVQ62_05500	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LVQ62_05505	COG0484	heat shock protein binding
LVQ62_05510	COG0789	Transcriptional regulator
LVQ62_05515	COG1619	proteins homologs of microcin C7 resistance protein MccF
LVQ62_05535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LVQ62_05555	COG2755	lipolytic protein G-D-S-L family
LVQ62_05620	COG2226	methyltransferase
LVQ62_05630	COG0604	alcohol dehydrogenase
LVQ62_05630	COG3321	synthase
LVQ62_05635	COG2197	response regulator
LVQ62_05645	COG1454	alcohol dehydrogenase
LVQ62_05650	COG2755	lipolytic protein G-D-S-L family
LVQ62_05665	COG0542	response to heat
LVQ62_05680	COG0477	Major facilitator Superfamily
LVQ62_05685	COG2072	flavoprotein involved in K transport
LVQ62_05740	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LVQ62_05790	COG4552	Acetyltransferase involved in intracellular survival and related
LVQ62_05820	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LVQ62_05830	COG2814	Major facilitator Superfamily
LVQ62_05835	COG2814	Major facilitator Superfamily
LVQ62_05840	COG2084	Dehydrogenase
LVQ62_05845	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LVQ62_05850	COG1605	Chorismate mutase
LVQ62_05850	COG0287	Prephenate dehydrogenase
LVQ62_05865	COG0151	Belongs to the GarS family
LVQ62_05875	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LVQ62_05880	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LVQ62_05885	COG0047	phosphoribosylformylglycinamidine synthase activity
LVQ62_05890	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LVQ62_05895	COG3467	pyridoxamine 5'-phosphate
LVQ62_05900	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LVQ62_05935	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LVQ62_05965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LVQ62_05965	COG1796	DNA polymerase
LVQ62_06000	COG0702	epimerase
LVQ62_06015	COG0667	Aldo Keto reductase
LVQ62_06020	COG1876	peptidase activity
LVQ62_06025	COG0246	Mannitol dehydrogenase
LVQ62_06030	COG1904	glucuronate isomerase
LVQ62_06040	COG1606	tRNA processing
LVQ62_06045	COG1691	(AIR) carboxylase
LVQ62_06050	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LVQ62_06085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LVQ62_06095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LVQ62_06100	COG0581	inorganic phosphate transmembrane transporter activity
LVQ62_06135	COG2376	Dihydroxyacetone kinase
LVQ62_06145	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LVQ62_06150	COG0456	acetyltransferase
LVQ62_06165	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_06185	COG0745	RESPONSE REGULATOR receiver
LVQ62_06200	COG3485	protocatechuate 3,4-dioxygenase
LVQ62_06210	COG0354	folic acid binding
LVQ62_06215	COG2226	methyltransferase
LVQ62_06235	COG1490	D-aminoacyl-tRNA deacylase activity
LVQ62_06255	COG0438	transferase activity, transferring glycosyl groups
LVQ62_06265	COG0588	phosphoglycerate mutase activity
LVQ62_06280	COG5002	protein histidine kinase activity
LVQ62_06285	COG0745	RESPONSE REGULATOR receiver
LVQ62_06295	COG1329	Transcriptional regulator
LVQ62_06315	COG0667	Aldo Keto reductase
LVQ62_06330	COG0215	cysteine-tRNA ligase activity
LVQ62_06340	COG1473	amidohydrolase
LVQ62_06355	COG1073	alpha beta
LVQ62_06410	COG0561	phosphatase activity
LVQ62_06410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LVQ62_06425	COG0515	serine threonine protein kinase
LVQ62_06425	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LVQ62_06435	COG1652	LysM domain
LVQ62_06460	COG1116	anion transmembrane transporter activity
LVQ62_06475	COG4191	Histidine kinase
LVQ62_06480	COG4565	transcriptional regulatory protein
LVQ62_06500	COG1132	(ABC) transporter
LVQ62_06510	COG0644	oxidoreductase
LVQ62_06535	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LVQ62_06540	COG2808	Putative FMN-binding domain
LVQ62_06545	COG0386	Belongs to the glutathione peroxidase family
LVQ62_06550	COG1169	isochorismate synthase
LVQ62_06555	COG1073	alpha beta
LVQ62_06560	COG2226	methyltransferase
LVQ62_06580	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LVQ62_06585	COG0649	NAD binding
LVQ62_06600	COG1034	ATP synthesis coupled electron transport
LVQ62_06605	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LVQ62_06610	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LVQ62_06615	COG0839	Belongs to the complex I subunit 6 family
LVQ62_06640	COG0142	geranyltranstransferase activity
LVQ62_06670	COG2197	response regulator
LVQ62_06705	COG1013	pyruvate-flavodoxin oxidoreductase activity
LVQ62_06710	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LVQ62_06710	COG0674	pyruvate-flavodoxin oxidoreductase activity
LVQ62_06720	COG0829	nickel cation binding
LVQ62_06725	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LVQ62_06735	COG0804	urea catabolic process
LVQ62_06750	COG0686	Belongs to the AlaDH PNT family
LVQ62_06755	COG1522	sequence-specific DNA binding
LVQ62_06770	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LVQ62_06775	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LVQ62_06780	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LVQ62_06785	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LVQ62_06795	COG0713	ATP synthesis coupled electron transport
LVQ62_06810	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LVQ62_06815	COG1007	ATP synthesis coupled electron transport
LVQ62_06820	COG0501	Belongs to the peptidase M48B family
LVQ62_06885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LVQ62_06890	COG1666	GTP binding
LVQ62_06900	COG0477	Major facilitator Superfamily
LVQ62_06920	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_06925	COG2030	dehydratase
LVQ62_06940	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LVQ62_06945	COG2030	dehydratase
LVQ62_06955	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LVQ62_06975	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LVQ62_06980	COG0508	dehydrogenase complex catalyzes the overall conversion of
LVQ62_06985	COG0022	dehydrogenase e1 component
LVQ62_06995	COG1522	sequence-specific DNA binding
LVQ62_07015	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LVQ62_07030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LVQ62_07035	COG0222	ribosome binding
LVQ62_07045	COG0085	RNA polymerase activity
LVQ62_07050	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LVQ62_07075	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LVQ62_07080	COG0049	tRNA binding
LVQ62_07085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LVQ62_07090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LVQ62_07110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LVQ62_07115	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LVQ62_07135	COG0546	phosphoglycolate phosphatase activity
LVQ62_07140	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LVQ62_07160	COG1181	Belongs to the D-alanine--D-alanine ligase family
LVQ62_07165	COG2409	Drug exporters of the RND superfamily
LVQ62_07170	COG1309	transcriptional regulator
LVQ62_07175	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_07195	COG1131	(ABC) transporter
LVQ62_07210	COG0051	transcription antitermination factor activity, RNA binding
LVQ62_07215	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LVQ62_07220	COG0088	Forms part of the polypeptide exit tunnel
LVQ62_07225	COG0089	rRNA binding
LVQ62_07230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LVQ62_07235	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LVQ62_07240	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LVQ62_07245	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LVQ62_07250	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LVQ62_07260	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LVQ62_07265	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LVQ62_07270	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LVQ62_07275	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LVQ62_07280	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LVQ62_07285	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LVQ62_07290	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LVQ62_07295	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LVQ62_07305	COG1841	ribosomal large subunit assembly
LVQ62_07310	COG0200	Binds to the 23S rRNA
LVQ62_07320	COG0563	adenylate kinase activity
LVQ62_07335	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LVQ62_07340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LVQ62_07345	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LVQ62_07350	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LVQ62_07360	COG0202	RNA polymerase activity
LVQ62_07365	COG0203	ribosomal protein L17
LVQ62_07375	COG0738	Major facilitator superfamily
LVQ62_07380	COG0101	tRNA pseudouridine synthase activity
LVQ62_07385	COG1984	allophanate hydrolase subunit 2
LVQ62_07395	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LVQ62_07400	COG2318	DinB family
LVQ62_07405	COG0488	(ABC) transporter
LVQ62_07440	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LVQ62_07445	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LVQ62_07450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LVQ62_07455	COG1764	response to oxidative stress
LVQ62_07490	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LVQ62_07490	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LVQ62_07520	COG0300	oxidoreductase activity
LVQ62_07540	COG0477	Major facilitator Superfamily
LVQ62_07545	COG1722	exodeoxyribonuclease VII activity
LVQ62_07550	COG1570	exodeoxyribonuclease VII activity
LVQ62_07555	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LVQ62_07560	COG1322	Protein conserved in bacteria
LVQ62_07575	COG1595	DNA-templated transcription, initiation
LVQ62_07630	COG3654	unkown
LVQ62_07675	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LVQ62_07680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LVQ62_07690	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LVQ62_07710	COG2197	response regulator
LVQ62_07720	COG2409	Drug exporters of the RND superfamily
LVQ62_07725	COG2409	Drug exporters of the RND superfamily
LVQ62_07735	COG0789	Transcriptional regulator
LVQ62_07745	COG1217	gtp-binding protein TYPA
LVQ62_07750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LVQ62_07760	COG2720	vancomycin resistance protein
LVQ62_07765	COG2814	Major facilitator Superfamily
LVQ62_07775	COG0456	acetyltransferase
LVQ62_07775	COG0454	-acetyltransferase
LVQ62_07815	COG0138	bifunctional purine biosynthesis protein purh
LVQ62_07820	COG0432	Pfam Uncharacterised protein family UPF0047
LVQ62_07835	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LVQ62_07845	COG0039	L-malate dehydrogenase activity
LVQ62_07865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LVQ62_07880	COG2244	polysaccharide biosynthetic process
LVQ62_07885	COG0489	protein tyrosine kinase activity
LVQ62_07920	COG0673	inositol 2-dehydrogenase activity
LVQ62_07985	COG0708	Exodeoxyribonuclease III
LVQ62_08040	COG0110	maltose O-acetyltransferase activity
LVQ62_08070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LVQ62_08075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LVQ62_08080	COG1086	Polysaccharide biosynthesis protein
LVQ62_08085	COG0489	protein tyrosine kinase activity
LVQ62_08085	COG3206	protein involved in exopolysaccharide biosynthesis
LVQ62_08090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LVQ62_08100	COG1349	DNA-binding transcription factor activity
LVQ62_08105	COG0180	Tryptophanyl-tRNA synthetase
LVQ62_08120	COG1053	succinate dehydrogenase
LVQ62_08130	COG0438	transferase activity, transferring glycosyl groups
LVQ62_08135	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LVQ62_08135	COG0662	Cupin 2, conserved barrel domain protein
LVQ62_08140	COG0167	dihydroorotate dehydrogenase activity
LVQ62_08150	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LVQ62_08150	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LVQ62_08170	COG1473	amidohydrolase
LVQ62_08170	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LVQ62_08175	COG1744	ABC transporter substrate-binding protein PnrA-like
LVQ62_08185	COG3845	ABC transporter
LVQ62_08190	COG4603	Belongs to the binding-protein-dependent transport system permease family
LVQ62_08195	COG1079	Belongs to the binding-protein-dependent transport system permease family
LVQ62_08215	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LVQ62_08240	COG0714	Associated with various cellular activities
LVQ62_08260	COG1012	belongs to the aldehyde dehydrogenase family
LVQ62_08265	COG1012	belongs to the aldehyde dehydrogenase family
LVQ62_08270	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LVQ62_08280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LVQ62_08305	COG4770	biotin carboxylase activity
LVQ62_08310	COG0656	L-ascorbic acid biosynthetic process
LVQ62_08325	COG0542	response to heat
LVQ62_08345	COG0765	amino acid transport
LVQ62_08385	COG0604	alcohol dehydrogenase
LVQ62_08405	COG0508	dehydrogenase complex catalyzes the overall conversion of
LVQ62_08405	COG0567	Dehydrogenase, E1 component
LVQ62_08420	COG1253	flavin adenine dinucleotide binding
LVQ62_08435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LVQ62_08440	COG2151	metal-sulfur cluster biosynthetic enzyme
LVQ62_08445	COG3396	Phenylacetate-CoA oxygenase
LVQ62_08450	COG3460	Phenylacetate-CoA oxygenase
LVQ62_08455	COG3396	Phenylacetate-CoA oxygenase
LVQ62_08465	COG2050	protein possibly involved in aromatic compounds catabolism
LVQ62_08470	COG1309	transcriptional regulator
LVQ62_08475	COG1942	4-Oxalocrotonate Tautomerase
LVQ62_08500	COG0460	homoserine dehydrogenase
LVQ62_08505	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LVQ62_08510	COG0083	homoserine kinase activity
LVQ62_08520	COG0477	Major facilitator Superfamily
LVQ62_08525	COG0254	rRNA binding
LVQ62_08530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LVQ62_08535	COG2890	protein-(glutamine-N5) methyltransferase activity
LVQ62_08545	COG1012	belongs to the aldehyde dehydrogenase family
LVQ62_08550	COG2226	methyltransferase
LVQ62_08560	COG0531	amino acid
LVQ62_08580	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LVQ62_08590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LVQ62_08600	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LVQ62_08605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LVQ62_08615	COG0356	it plays a direct role in the translocation of protons across the membrane
LVQ62_08620	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LVQ62_08625	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LVQ62_08630	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LVQ62_08635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LVQ62_08640	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LVQ62_08645	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LVQ62_08685	COG1595	DNA-templated transcription, initiation
LVQ62_08700	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LVQ62_08705	COG1250	3-hydroxyacyl-CoA dehydrogenase
LVQ62_08715	COG0861	Integral membrane protein TerC family
LVQ62_08720	COG0346	lactoylglutathione lyase activity
LVQ62_08725	COG0183	Belongs to the thiolase family
LVQ62_08755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LVQ62_08760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LVQ62_08770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LVQ62_08770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LVQ62_08770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LVQ62_08775	COG1105	Belongs to the carbohydrate kinase PfkB family
LVQ62_08780	COG1349	DNA-binding transcription factor activity
LVQ62_08785	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LVQ62_08785	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LVQ62_08825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LVQ62_08835	COG0366	Alpha amylase catalytic
LVQ62_08845	COG0028	Belongs to the TPP enzyme family
LVQ62_08850	COG0069	glutamate synthase activity
LVQ62_08855	COG3619	membrane
LVQ62_08895	COG2086	electron transfer activity
LVQ62_08900	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LVQ62_08910	COG3467	pyridoxamine 5'-phosphate
LVQ62_08925	COG0482	sulfurtransferase activity
LVQ62_08945	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LVQ62_08960	COG1024	Enoyl-CoA hydratase
LVQ62_08970	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LVQ62_08975	COG0154	amidase activity
LVQ62_08980	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LVQ62_09010	COG0477	Major facilitator Superfamily
LVQ62_09020	COG0129	dihydroxy-acid dehydratase activity
LVQ62_09025	COG1131	(ABC) transporter
LVQ62_09045	COG0440	acetolactate synthase activity
LVQ62_09050	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LVQ62_09055	COG0473	3-isopropylmalate dehydrogenase activity
LVQ62_09060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LVQ62_09065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LVQ62_09070	COG0179	Fumarylacetoacetate (FAA) hydrolase
LVQ62_09075	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LVQ62_09080	COG1234	tRNA 3'-trailer cleavage
LVQ62_09085	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LVQ62_09090	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LVQ62_09155	COG1295	ribonuclease BN
LVQ62_09210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LVQ62_09270	COG1946	Acyl-CoA thioesterase
LVQ62_09285	COG0366	Alpha amylase catalytic
LVQ62_09295	COG0668	transmembrane transport
LVQ62_09315	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LVQ62_09345	COG0544	peptidyl-prolyl cis-trans isomerase activity
LVQ62_09350	COG0740	serine-type endopeptidase activity
LVQ62_09355	COG0740	serine-type endopeptidase activity
LVQ62_09365	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LVQ62_09380	COG0714	Associated with various cellular activities
LVQ62_09395	COG0525	valine-tRNA ligase activity
LVQ62_09410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LVQ62_09420	COG0285	dihydrofolate synthase activity
LVQ62_09430	COG1968	undecaprenyl-diphosphatase activity
LVQ62_09435	COG0105	UTP biosynthetic process
LVQ62_09445	COG2267	carboxylic ester hydrolase activity
LVQ62_09455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LVQ62_09490	COG0702	epimerase
LVQ62_09495	COG2814	Major facilitator Superfamily
LVQ62_09500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LVQ62_09505	COG2764	glyoxalase bleomycin resistance protein dioxygenase
LVQ62_09525	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LVQ62_09530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LVQ62_09535	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LVQ62_09565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LVQ62_09580	COG1674	ftsk spoiiie
LVQ62_09600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LVQ62_09610	COG1546	Belongs to the CinA family
LVQ62_09610	COG1058	Belongs to the CinA family
LVQ62_09615	COG1396	sequence-specific DNA binding
LVQ62_09620	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LVQ62_09625	COG1201	RNA secondary structure unwinding
LVQ62_09630	COG2957	Belongs to the agmatine deiminase family
LVQ62_09635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LVQ62_09645	COG1305	Transglutaminase-like
LVQ62_09650	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LVQ62_09660	COG1280	lysine exporter protein (LysE YggA)
LVQ62_09665	COG0277	FAD linked oxidase domain protein
LVQ62_09675	COG2814	Major facilitator Superfamily
LVQ62_09695	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LVQ62_09700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LVQ62_09715	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LVQ62_09720	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LVQ62_09725	COG2813	Specifically methylates the guanine in position
LVQ62_09735	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LVQ62_09760	COG0268	Binds directly to 16S ribosomal RNA
LVQ62_09770	COG1307	EDD domain protein, DegV family
LVQ62_09775	COG2183	response to ionizing radiation
LVQ62_09780	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LVQ62_09780	COG0321	lipoyl(octanoyl) transferase activity
LVQ62_09790	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LVQ62_09795	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LVQ62_09805	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LVQ62_09810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LVQ62_09865	COG0489	protein tyrosine kinase activity
LVQ62_09875	COG0438	transferase activity, transferring glycosyl groups
LVQ62_09910	COG2089	acid synthase
LVQ62_09915	COG1083	cytidylyl-transferase
LVQ62_09940	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LVQ62_09955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LVQ62_09965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LVQ62_09975	COG1401	restriction endodeoxyribonuclease activity
LVQ62_10005	COG2733	membrane
LVQ62_10030	COG1643	Atp-dependent helicase
LVQ62_10040	COG0537	adenosine 5'-monophosphoramidase activity
LVQ62_10095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LVQ62_10100	COG0589	response to stress
LVQ62_10105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LVQ62_10120	COG0714	Associated with various cellular activities
LVQ62_10130	COG0275	rRNA processing
LVQ62_10140	COG0768	penicillin binding
LVQ62_10145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LVQ62_10150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LVQ62_10155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LVQ62_10165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LVQ62_10170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LVQ62_10175	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LVQ62_10190	COG1799	cell septum assembly
LVQ62_10215	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LVQ62_10220	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LVQ62_10245	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LVQ62_10265	COG2409	Drug exporters of the RND superfamily
LVQ62_10295	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LVQ62_10300	COG1335	isochorismatase
LVQ62_10305	COG0321	lipoyl(octanoyl) transferase activity
LVQ62_10310	COG0372	Belongs to the citrate synthase family
LVQ62_10320	COG0515	serine threonine protein kinase
LVQ62_10320	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LVQ62_10355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LVQ62_10360	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LVQ62_10365	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LVQ62_10395	COG0435	Glutathione S-transferase
LVQ62_10425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LVQ62_10430	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LVQ62_10435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LVQ62_10440	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LVQ62_10450	COG2130	NADP-dependent
LVQ62_10455	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LVQ62_10460	COG0723	plastoquinol--plastocyanin reductase activity
LVQ62_10465	COG2010	Cytochrome c
LVQ62_10470	COG1845	cytochrome c oxidase, subunit III
LVQ62_10480	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LVQ62_10520	COG1940	carbohydrate kinase activity
LVQ62_10525	COG1940	carbohydrate kinase activity
LVQ62_10550	COG0393	Putative heavy-metal-binding
LVQ62_10560	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LVQ62_10565	COG0515	serine threonine protein kinase
LVQ62_10565	COG2815	serine threonine protein kinase
LVQ62_10575	COG0142	geranyltranstransferase activity
LVQ62_10605	COG0187	DNA topoisomerase II activity
LVQ62_10610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LVQ62_10625	COG1196	nuclear chromosome segregation
LVQ62_10630	COG2318	DinB family
LVQ62_10650	COG0673	inositol 2-dehydrogenase activity
LVQ62_10660	COG1609	Transcriptional regulator
LVQ62_10670	COG1175	transmembrane transport
LVQ62_10685	COG3842	ATPase activity
LVQ62_10705	COG0778	Nitroreductase
LVQ62_10710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LVQ62_10715	COG1595	DNA-templated transcription, initiation
LVQ62_10725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LVQ62_10725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LVQ62_10740	COG1435	thymidine kinase activity
LVQ62_10745	COG2814	Major facilitator Superfamily
LVQ62_10755	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LVQ62_10770	COG0756	dUTP diphosphatase activity
LVQ62_10790	COG0569	domain protein
LVQ62_10795	COG0531	amino acid
LVQ62_10800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LVQ62_10805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LVQ62_10830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LVQ62_10835	COG1063	alcohol dehydrogenase
LVQ62_10845	COG1396	sequence-specific DNA binding
LVQ62_10850	COG0740	serine-type endopeptidase activity
LVQ62_10855	COG0740	serine-type endopeptidase activity
LVQ62_10870	COG1024	Enoyl-CoA hydratase
LVQ62_10870	COG1250	3-hydroxyacyl-CoA dehydrogenase
LVQ62_10875	COG0183	Belongs to the thiolase family
LVQ62_10900	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LVQ62_10905	COG2364	Membrane
LVQ62_10910	COG0436	Aminotransferase
LVQ62_10920	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LVQ62_10925	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LVQ62_10930	COG3253	May function as heme-dependent peroxidase
LVQ62_10935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LVQ62_10945	COG3285	dna ligase
LVQ62_10945	COG1793	dna ligase
LVQ62_10975	COG2326	polyphosphate kinase activity
LVQ62_11100	COG0437	4 iron, 4 sulfur cluster binding
LVQ62_11115	COG0688	phosphatidylethanolamine metabolic process
LVQ62_11160	COG0444	Belongs to the ABC transporter superfamily
LVQ62_11180	COG4948	Mandelate Racemase Muconate Lactonizing
LVQ62_11225	COG0667	Aldo Keto reductase
LVQ62_11260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LVQ62_11265	COG1193	negative regulation of DNA recombination
LVQ62_11280	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LVQ62_11285	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LVQ62_11355	COG0038	chloride channel
LVQ62_11365	COG2188	Transcriptional regulator
LVQ62_11370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LVQ62_11375	COG0446	pyridine nucleotide-disulphide oxidoreductase
LVQ62_11420	COG3608	succinylglutamate desuccinylase aspartoacylase
LVQ62_11435	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_11455	COG0601	transmembrane transport
LVQ62_11460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LVQ62_11465	COG0444	Belongs to the ABC transporter superfamily
LVQ62_11470	COG4608	Belongs to the ABC transporter superfamily
LVQ62_11490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LVQ62_11495	COG0589	response to stress
LVQ62_11500	COG2814	Major facilitator Superfamily
LVQ62_11550	COG2197	response regulator
LVQ62_11555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LVQ62_11570	COG4221	oxidoreductase activity
LVQ62_11580	COG3384	dioxygenase
LVQ62_11600	COG0640	Transcriptional regulator
LVQ62_11635	COG4221	oxidoreductase activity
LVQ62_11645	COG2115	Belongs to the xylose isomerase family
LVQ62_11655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LVQ62_11665	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LVQ62_11700	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LVQ62_11705	COG1560	Kdo2-lipid A biosynthetic process
LVQ62_11720	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LVQ62_11730	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LVQ62_11730	COG2755	lipolytic protein G-D-S-L family
LVQ62_11740	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LVQ62_11740	COG2755	lipolytic protein G-D-S-L family
LVQ62_11745	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LVQ62_11745	COG2755	lipolytic protein G-D-S-L family
LVQ62_11775	COG0438	transferase activity, transferring glycosyl groups
LVQ62_11825	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LVQ62_11835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LVQ62_11840	COG2226	methyltransferase
LVQ62_11865	COG3842	ATPase activity
LVQ62_11875	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LVQ62_11875	COG0237	dephospho-CoA kinase activity
LVQ62_11900	COG0556	nucleotide-excision repair
LVQ62_11930	COG0791	NLP P60 protein
LVQ62_11935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LVQ62_11940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LVQ62_11955	COG1660	Displays ATPase and GTPase activities
LVQ62_11965	COG1481	regulation of sporulation
LVQ62_11970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LVQ62_11975	COG0126	phosphoglycerate kinase activity
LVQ62_11980	COG0149	triose-phosphate isomerase activity
LVQ62_12005	COG0363	glucosamine-6-phosphate deaminase activity
LVQ62_12025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LVQ62_12035	COG0109	protoheme IX farnesyltransferase activity
LVQ62_12040	COG1612	heme a metabolic process
LVQ62_12070	COG0719	Fe-S assembly protein
LVQ62_12080	COG0396	ATPase activity
LVQ62_12095	COG2151	metal-sulfur cluster biosynthetic enzyme
LVQ62_12145	COG2271	Major facilitator Superfamily
LVQ62_12155	COG0488	(ABC) transporter
LVQ62_12170	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LVQ62_12185	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_12195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LVQ62_12195	COG0189	ligase activity
LVQ62_12200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LVQ62_12200	COG1181	Belongs to the D-alanine--D-alanine ligase family
LVQ62_12205	COG4242	Belongs to the peptidase S51 family
LVQ62_12210	COG0560	Phosphoserine phosphatase
LVQ62_12210	COG3830	Belongs to the UPF0237 family
LVQ62_12215	COG0560	Phosphoserine phosphatase
LVQ62_12215	COG3830	Belongs to the UPF0237 family
LVQ62_12220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LVQ62_12225	COG0297	glycogen (starch) synthase activity
LVQ62_12235	COG1119	ATPase activity
LVQ62_12255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LVQ62_12280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LVQ62_12300	COG0076	glutamate decarboxylase activity
LVQ62_12325	COG1793	dna ligase
LVQ62_12345	COG0667	Aldo Keto reductase
LVQ62_12350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LVQ62_12370	COG0215	cysteine-tRNA ligase activity
LVQ62_12390	COG0456	acetyltransferase
LVQ62_12440	COG1276	copper resistance
LVQ62_12440	COG2372	response to copper ion
LVQ62_12445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LVQ62_12495	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LVQ62_12530	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LVQ62_12545	COG1335	isochorismatase
LVQ62_12590	COG1216	Glycosyl transferase, family 2
LVQ62_12595	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LVQ62_12605	COG1522	sequence-specific DNA binding
LVQ62_12625	COG0805	protein transport
LVQ62_12665	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LVQ62_12670	COG1132	(ABC) transporter
LVQ62_12675	COG1132	(ABC) transporter
LVQ62_12685	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LVQ62_12690	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LVQ62_12700	COG4122	O-methyltransferase activity
LVQ62_12725	COG0330	HflC and HflK could
LVQ62_12740	COG0277	FAD linked oxidase domain protein
LVQ62_12755	COG1222	aaa ATPase
LVQ62_12765	COG1994	Peptidase M50
LVQ62_12765	COG0517	IMP dehydrogenase activity
LVQ62_12775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LVQ62_12790	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LVQ62_12805	COG0318	PFAM AMP-dependent synthetase and ligase
LVQ62_12810	COG1960	acyl-CoA dehydrogenase activity
LVQ62_12820	COG1960	acyl-CoA dehydrogenase activity
LVQ62_12840	COG1011	Hydrolase
LVQ62_12850	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_12855	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_12860	COG0183	Belongs to the thiolase family
LVQ62_12870	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LVQ62_12870	COG2755	lipolytic protein G-D-S-L family
LVQ62_12895	COG0009	L-threonylcarbamoyladenylate synthase
LVQ62_12910	COG0406	alpha-ribazole phosphatase activity
LVQ62_12925	COG0420	3'-5' exonuclease activity
LVQ62_12930	COG0419	ATPase involved in DNA repair
LVQ62_12940	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LVQ62_12940	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LVQ62_12960	COG1716	ATPase activity
LVQ62_12990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LVQ62_13045	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_13065	COG1160	GTP binding
LVQ62_13075	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LVQ62_13090	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LVQ62_13095	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LVQ62_13120	COG0124	histidyl-tRNA synthetase
LVQ62_13135	COG1196	nuclear chromosome segregation
LVQ62_13140	COG1362	aminopeptidase activity
LVQ62_13150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LVQ62_13155	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LVQ62_13160	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LVQ62_13165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LVQ62_13180	COG0632	four-way junction helicase activity
LVQ62_13185	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LVQ62_13190	COG0217	transcriptional regulatory protein
LVQ62_13195	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LVQ62_13210	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
LVQ62_13220	COG1120	ATPase activity
LVQ62_13225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LVQ62_13235	COG1116	anion transmembrane transporter activity
LVQ62_13245	COG2050	protein possibly involved in aromatic compounds catabolism
LVQ62_13270	COG0559	Belongs to the binding-protein-dependent transport system permease family
LVQ62_13275	COG0683	leucine binding
LVQ62_13295	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LVQ62_13345	COG0159	tryptophan synthase activity
LVQ62_13350	COG0133	tryptophan synthase activity
LVQ62_13355	COG0134	indole-3-glycerol-phosphate synthase activity
LVQ62_13375	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LVQ62_13400	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LVQ62_13405	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LVQ62_13425	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LVQ62_13430	COG1132	(ABC) transporter
LVQ62_13435	COG1132	(ABC) transporter
LVQ62_13445	COG0107	imidazoleglycerol-phosphate synthase activity
LVQ62_13460	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LVQ62_13465	COG0140	phosphoribosyl-ATP diphosphatase activity
LVQ62_13470	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LVQ62_13475	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LVQ62_13475	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LVQ62_13480	COG3201	nicotinamide mononucleotide transporter
LVQ62_13495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LVQ62_13505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LVQ62_13510	COG0242	peptide deformylase activity
LVQ62_13540	COG1758	RNA polymerase activity
LVQ62_13545	COG0194	GDP metabolic process
LVQ62_13555	COG0284	orotidine-5'-phosphate decarboxylase activity
LVQ62_13565	COG0505	Belongs to the CarA family
LVQ62_13570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LVQ62_13580	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LVQ62_13590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LVQ62_13595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LVQ62_13600	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LVQ62_13605	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LVQ62_13610	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LVQ62_13615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LVQ62_13625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LVQ62_13630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LVQ62_13635	COG4608	Belongs to the ABC transporter superfamily
LVQ62_13645	COG0601	transmembrane transport
LVQ62_13655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LVQ62_13660	COG0747	negative chemotaxis
LVQ62_13695	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LVQ62_13700	COG3012	SEC-C Motif Domain Protein
LVQ62_13710	COG0137	argininosuccinate synthase activity
LVQ62_13725	COG0436	Aminotransferase
LVQ62_13730	COG0494	nUDIX hydrolase
LVQ62_13735	COG0504	CTP synthase activity
LVQ62_13740	COG0497	DNA recombination
LVQ62_13745	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LVQ62_13770	COG0647	UMP catabolic process
LVQ62_13805	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LVQ62_13810	COG2094	Belongs to the DNA glycosylase MPG family
LVQ62_13815	COG0165	Argininosuccinate lyase
LVQ62_13820	COG1438	arginine binding
LVQ62_13835	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LVQ62_13840	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LVQ62_13845	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LVQ62_13855	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LVQ62_13860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LVQ62_13865	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LVQ62_13870	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LVQ62_13875	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LVQ62_13905	COG1070	Carbohydrate kinase
LVQ62_13915	COG0395	ABC-type sugar transport system, permease component
LVQ62_13940	COG0672	)-iron permease
LVQ62_13950	COG2837	iron assimilation
LVQ62_13985	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LVQ62_13990	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LVQ62_14000	COG0131	Imidazoleglycerol-phosphate dehydratase
LVQ62_14005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LVQ62_14010	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LVQ62_14015	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LVQ62_14025	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LVQ62_14035	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LVQ62_14040	COG0477	Major facilitator Superfamily
LVQ62_14125	COG3022	response to hydroperoxide
LVQ62_14130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LVQ62_14155	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LVQ62_14185	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LVQ62_14190	COG0584	glycerophosphoryl diester phosphodiesterase
LVQ62_14205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LVQ62_14210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LVQ62_14230	COG1316	TRANSCRIPTIONal
LVQ62_14250	COG1876	peptidase activity
LVQ62_14280	COG2205	protein histidine kinase activity
LVQ62_14285	COG0745	RESPONSE REGULATOR receiver
LVQ62_14315	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LVQ62_14320	COG1970	mechanosensitive ion channel activity
LVQ62_14325	COG0038	chloride channel
LVQ62_14330	COG1024	Enoyl-CoA hydratase
LVQ62_14335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LVQ62_14340	COG1250	3-hydroxyacyl-CoA dehydrogenase
LVQ62_14355	COG1846	Transcriptional regulator
LVQ62_14390	COG3485	protocatechuate 3,4-dioxygenase
LVQ62_14395	COG3485	protocatechuate 3,4-dioxygenase
LVQ62_14400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LVQ62_14405	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LVQ62_14435	COG1192	Involved in chromosome partitioning
LVQ62_14480	COG1846	Transcriptional regulator
LVQ62_14495	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_14505	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_14530	COG3387	PFAM Glycoside hydrolase 15-related
LVQ62_14535	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_14585	COG2070	2-Nitropropane dioxygenase
LVQ62_14590	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LVQ62_14620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LVQ62_14625	COG2197	response regulator
LVQ62_14630	COG4585	Histidine kinase
LVQ62_14640	COG1131	(ABC) transporter
LVQ62_14660	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LVQ62_14665	COG1381	Involved in DNA repair and RecF pathway recombination
LVQ62_14675	COG1960	acyl-CoA dehydrogenase activity
LVQ62_14680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LVQ62_14690	COG2124	cytochrome p450
LVQ62_14700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LVQ62_14705	COG3119	arylsulfatase activity
LVQ62_14710	COG1403	HNH endonuclease
LVQ62_14735	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LVQ62_14740	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LVQ62_14750	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LVQ62_14765	COG0484	heat shock protein binding
LVQ62_14770	COG1420	regulation of RNA biosynthetic process
LVQ62_14785	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LVQ62_14790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LVQ62_14795	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LVQ62_14815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LVQ62_14820	COG0481	GTPase activity
LVQ62_14830	COG2814	Major facilitator Superfamily
LVQ62_14840	COG2986	histidine ammonia-lyase
LVQ62_14845	COG1414	Transcriptional regulator
LVQ62_14850	COG1125	glycine betaine transport
LVQ62_14850	COG0517	IMP dehydrogenase activity
LVQ62_14855	COG1174	glycine betaine transport
LVQ62_14875	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LVQ62_14885	COG1960	acyl-CoA dehydrogenase activity
LVQ62_14900	COG1960	acyl-CoA dehydrogenase activity
LVQ62_14910	COG0640	Transcriptional regulator
LVQ62_14925	COG0667	Aldo Keto reductase
LVQ62_14945	COG0406	alpha-ribazole phosphatase activity
LVQ62_14950	COG0799	negative regulation of ribosome biogenesis
LVQ62_14955	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LVQ62_14965	COG0463	Glycosyl transferase, family 2
LVQ62_14970	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LVQ62_14980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LVQ62_14985	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LVQ62_14990	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LVQ62_14995	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LVQ62_15000	COG1530	ribonuclease E activity
LVQ62_15010	COG1215	transferase activity, transferring glycosyl groups
LVQ62_15030	COG1022	Amp-dependent synthetase and ligase
LVQ62_15035	COG0196	riboflavin kinase activity
LVQ62_15040	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LVQ62_15045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LVQ62_15050	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LVQ62_15060	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LVQ62_15060	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LVQ62_15075	COG0779	Required for maturation of 30S ribosomal subunits
LVQ62_15080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LVQ62_15085	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LVQ62_15105	COG0529	Catalyzes the synthesis of activated sulfate
LVQ62_15110	COG0175	sulfate reduction
LVQ62_15120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LVQ62_15130	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
LVQ62_15150	COG0442	prolyl-tRNA aminoacylation
LVQ62_15155	COG1960	acyl-CoA dehydrogenase activity
LVQ62_15165	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LVQ62_15175	COG0456	acetyltransferase
LVQ62_15175	COG0454	-acetyltransferase
LVQ62_15190	COG0750	zinc metalloprotease
LVQ62_15195	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LVQ62_15225	COG1012	belongs to the aldehyde dehydrogenase family
LVQ62_15230	COG1760	l-serine dehydratase
LVQ62_15240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LVQ62_15250	COG3268	Saccharopine dehydrogenase
LVQ62_15270	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LVQ62_15280	COG0233	cytoplasmic translational termination
LVQ62_15285	COG0528	UMP kinase activity
LVQ62_15290	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LVQ62_15295	COG0052	Belongs to the universal ribosomal protein uS2 family
LVQ62_15315	COG4991	sh3 domain protein
LVQ62_15330	COG4974	Belongs to the 'phage' integrase family
LVQ62_15345	COG0792	nuclease activity
LVQ62_15360	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LVQ62_15370	COG0681	Belongs to the peptidase S26 family
LVQ62_15375	COG0335	large ribosomal subunit rRNA binding
LVQ62_15380	COG0336	Belongs to the RNA methyltransferase TrmD family
LVQ62_15385	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LVQ62_15400	COG0738	Major facilitator superfamily
LVQ62_15405	COG1837	Belongs to the UPF0109 family
LVQ62_15410	COG0228	four-way junction DNA binding
LVQ62_15415	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LVQ62_15435	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LVQ62_15550	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LVQ62_15570	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LVQ62_15600	COG0789	Transcriptional regulator
LVQ62_15605	COG0038	chloride channel
LVQ62_15615	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_15620	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_15625	COG3387	PFAM Glycoside hydrolase 15-related
LVQ62_15630	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_15640	COG3883	PFAM NLP P60 protein
LVQ62_15640	COG0791	NLP P60 protein
LVQ62_15675	COG0552	protein localization to endoplasmic reticulum
LVQ62_15690	COG1196	nuclear chromosome segregation
LVQ62_15700	COG2197	response regulator
LVQ62_15725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LVQ62_15730	COG0571	ribonuclease III activity
LVQ62_15735	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LVQ62_15745	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LVQ62_15750	COG0742	ribosomal rna small subunit methyltransferase
LVQ62_15755	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LVQ62_15760	COG1461	Dihydroxyacetone kinase
LVQ62_15765	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LVQ62_15775	COG1381	Involved in DNA repair and RecF pathway recombination
LVQ62_15815	COG1181	Belongs to the D-alanine--D-alanine ligase family
LVQ62_15825	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LVQ62_15835	COG1920	GTP binding
LVQ62_15845	COG0776	regulation of translation
LVQ62_15850	COG0066	3-isopropylmalate dehydratase activity
LVQ62_15855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LVQ62_15860	COG1414	Transcriptional regulator
LVQ62_15900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LVQ62_15910	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LVQ62_15920	COG1335	isochorismatase
LVQ62_15935	COG1714	RDD family
LVQ62_15970	COG0513	Belongs to the DEAD box helicase family
LVQ62_15995	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LVQ62_16015	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LVQ62_16055	COG1012	belongs to the aldehyde dehydrogenase family
LVQ62_16095	COG0653	protein targeting
LVQ62_16115	COG2197	response regulator
LVQ62_16120	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LVQ62_16125	COG5401	PFAM Sporulation and spore germination
LVQ62_16130	COG5002	protein histidine kinase activity
LVQ62_16135	COG0745	RESPONSE REGULATOR receiver
LVQ62_16140	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LVQ62_16170	COG3483	tryptophan 2,3-dioxygenase activity
LVQ62_16180	COG1663	tetraacyldisaccharide 4'-kinase activity
LVQ62_16180	COG2835	tetraacyldisaccharide 4'-kinase activity
LVQ62_16185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LVQ62_16225	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LVQ62_16230	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
LVQ62_16230	COG0778	Nitroreductase
LVQ62_16260	COG3579	cysteine-type endopeptidase activity
LVQ62_16270	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_16275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LVQ62_16290	COG2089	acid synthase
LVQ62_16295	COG1216	Glycosyl transferase, family 2
LVQ62_16325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LVQ62_16330	COG1086	Polysaccharide biosynthesis protein
LVQ62_16345	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
LVQ62_16385	COG1316	TRANSCRIPTIONal
LVQ62_16415	COG3850	Histidine kinase
LVQ62_16415	COG5002	protein histidine kinase activity
LVQ62_16420	COG0745	RESPONSE REGULATOR receiver
LVQ62_16430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LVQ62_16455	COG0424	maF-like protein
LVQ62_16465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LVQ62_16470	COG1960	acyl-CoA dehydrogenase activity
LVQ62_16505	COG1595	DNA-templated transcription, initiation
LVQ62_16510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LVQ62_16520	COG2135	peptidase activity
LVQ62_16525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LVQ62_16530	COG1162	GTPase activity
LVQ62_16535	COG1289	transmembrane transporter activity
LVQ62_16540	COG0483	inositol monophosphate 1-phosphatase activity
LVQ62_16575	COG1252	NADH dehydrogenase
LVQ62_16585	COG1131	(ABC) transporter
LVQ62_16585	COG1716	ATPase activity
LVQ62_16585	COG0842	Transport permease protein
LVQ62_16590	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LVQ62_16595	COG0739	heme binding
LVQ62_16595	COG0741	lytic transglycosylase activity
LVQ62_16595	COG1196	nuclear chromosome segregation
LVQ62_16605	COG2884	Cell division ATP-binding protein ftsE
LVQ62_16620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LVQ62_16685	COG1615	UPF0182 protein
LVQ62_16695	COG3480	Lon protease (S16) C-terminal proteolytic domain
LVQ62_16735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LVQ62_16800	COG0513	Belongs to the DEAD box helicase family
LVQ62_16820	COG0613	PHP domain protein
LVQ62_16835	COG0006	proline dipeptidase activity
LVQ62_16850	COG2239	Acts as a magnesium transporter
LVQ62_16865	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LVQ62_16875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LVQ62_16885	COG1595	DNA-templated transcription, initiation
LVQ62_16900	COG1024	Enoyl-CoA hydratase
LVQ62_16920	COG0519	Catalyzes the synthesis of GMP from XMP
LVQ62_16935	COG1611	Belongs to the LOG family
LVQ62_16940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LVQ62_16950	COG0667	Aldo Keto reductase
LVQ62_16975	COG0045	succinate-CoA ligase (ADP-forming) activity
LVQ62_16980	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LVQ62_16985	COG0739	heme binding
LVQ62_17030	COG2154	pterin-4-alpha-carbinolamine dehydratase
LVQ62_17070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LVQ62_17075	COG1657	PFAM Prenyltransferase squalene oxidase
LVQ62_17085	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LVQ62_17100	COG3835	regulator
LVQ62_17120	COG0300	oxidoreductase activity
LVQ62_17125	COG0519	Catalyzes the synthesis of GMP from XMP
LVQ62_17125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LVQ62_17145	COG1132	(ABC) transporter
LVQ62_17155	COG0516	GMP reductase activity
LVQ62_17170	COG1595	DNA-templated transcription, initiation
LVQ62_17180	COG0459	protein refolding
LVQ62_17185	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LVQ62_17200	COG1472	Belongs to the glycosyl hydrolase 3 family
LVQ62_17205	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LVQ62_17215	COG0456	acetyltransferase
LVQ62_17215	COG1214	PFAM Peptidase M22, glycoprotease
LVQ62_17220	COG0802	atpase or kinase
LVQ62_17230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LVQ62_17245	COG0736	holo-[acyl-carrier-protein] synthase activity
LVQ62_17250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LVQ62_17255	COG1072	(Pantothenic acid kinase))
LVQ62_17280	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LVQ62_17285	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LVQ62_17300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LVQ62_17310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LVQ62_17335	COG0751	glycine-tRNA ligase activity
LVQ62_17335	COG0752	glycyl-tRNA synthetase alpha subunit
LVQ62_17340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LVQ62_17350	COG0477	Major facilitator Superfamily
LVQ62_17350	COG2814	Major facilitator Superfamily
LVQ62_17355	COG1528	Iron-storage protein
LVQ62_17375	COG0587	DNA-directed DNA polymerase activity
LVQ62_17380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LVQ62_17385	COG1028	Short-chain dehydrogenase reductase Sdr
LVQ62_17390	COG1012	belongs to the aldehyde dehydrogenase family
LVQ62_17400	COG2186	Transcriptional regulator
LVQ62_17420	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LVQ62_17425	COG1331	Highly conserved protein containing a thioredoxin domain
LVQ62_17435	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LVQ62_17435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms