locus-tag	class	description
Mic7113_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Mic7113_0003	COG0592	DNA-directed DNA polymerase activity
Mic7113_0004	COG1672	PFAM Archaeal ATPase
Mic7113_0004	COG2319	Wd-40 repeat
Mic7113_0007	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Mic7113_0008	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Mic7113_0009	COG1830	Aldolase
Mic7113_0013	COG0436	Aminotransferase
Mic7113_0016	COG0589	response to stress
Mic7113_0018	COG1309	transcriptional regulator
Mic7113_0020	COG1610	YqeY-like protein
Mic7113_0021	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Mic7113_0022	COG1254	Belongs to the acylphosphatase family
Mic7113_0024	COG0697	spore germination
Mic7113_0025	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Mic7113_0036	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Mic7113_0037	COG0583	DNA-binding transcription factor activity
Mic7113_0039	COG0194	GDP metabolic process
Mic7113_0040	COG2052	Domain of unknown function (DUF370)
Mic7113_0043	COG1116	anion transmembrane transporter activity
Mic7113_0044	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Mic7113_0048	COG0375	protein maturation
Mic7113_0049	COG0010	Belongs to the arginase family
Mic7113_0051	COG1122	ATPase activity
Mic7113_0052	COG0357	Ribosomal RNA small subunit methyltransferase G
Mic7113_0053	COG0667	Aldo Keto reductase
Mic7113_0054	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Mic7113_0057	COG2183	response to ionizing radiation
Mic7113_0062	COG3386	PFAM SMP-30 Gluconolaconase
Mic7113_0064	COG0788	formyltetrahydrofolate deformylase activity
Mic7113_0067	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Mic7113_0069	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
Mic7113_0070	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Mic7113_0071	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Mic7113_0072	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Mic7113_0073	COG1773	rubredoxin
Mic7113_0074	COG4447	cellulose binding
Mic7113_0080	COG0124	histidyl-tRNA synthetase
Mic7113_0085	COG1191	sigma factor activity
Mic7113_0088	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Mic7113_0089	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Mic7113_0092	COG1501	Belongs to the glycosyl hydrolase 31 family
Mic7113_0093	COG0489	protein tyrosine kinase activity
Mic7113_0094	COG0438	transferase activity, transferring glycosyl groups
Mic7113_0096	COG1132	(ABC) transporter
Mic7113_0098	COG1216	Glycosyl transferase, family 2
Mic7113_0099	COG1216	Glycosyl transferase, family 2
Mic7113_0100	COG0438	transferase activity, transferring glycosyl groups
Mic7113_0107	COG0438	transferase activity, transferring glycosyl groups
Mic7113_0108	COG0438	transferase activity, transferring glycosyl groups
Mic7113_0115	COG0489	protein tyrosine kinase activity
Mic7113_0116	COG0772	Belongs to the SEDS family
Mic7113_0120	COG0475	glutathione-regulated potassium exporter activity
Mic7113_0120	COG0589	response to stress
Mic7113_0122	COG0525	valine-tRNA ligase activity
Mic7113_0123	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Mic7113_0123	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Mic7113_0126	COG0243	molybdopterin cofactor binding
Mic7113_0128	COG2223	nitrite transmembrane transporter activity
Mic7113_0129	COG1116	anion transmembrane transporter activity
Mic7113_0130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Mic7113_0130	COG1116	anion transmembrane transporter activity
Mic7113_0131	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Mic7113_0132	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Mic7113_0139	COG0730	response to heat
Mic7113_0143	COG0730	response to heat
Mic7113_0145	COG0824	Thioesterase
Mic7113_0146	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Mic7113_0148	COG0477	Major facilitator Superfamily
Mic7113_0149	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Mic7113_0153	COG0667	Aldo Keto reductase
Mic7113_0159	COG4106	trans-aconitate 2-methyltransferase activity
Mic7113_0173	COG1196	nuclear chromosome segregation
Mic7113_0173	COG3264	Mechanosensitive ion channel
Mic7113_0176	COG0159	tryptophan synthase activity
Mic7113_0180	COG2226	methyltransferase
Mic7113_0181	COG0515	serine threonine protein kinase
Mic7113_0181	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_0183	COG5002	protein histidine kinase activity
Mic7113_0184	COG0515	serine threonine protein kinase
Mic7113_0185	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Mic7113_0189	COG1253	flavin adenine dinucleotide binding
Mic7113_0190	COG0515	serine threonine protein kinase
Mic7113_0191	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Mic7113_0192	COG0673	inositol 2-dehydrogenase activity
Mic7113_0195	COG1253	flavin adenine dinucleotide binding
Mic7113_0204	COG0438	transferase activity, transferring glycosyl groups
Mic7113_0205	COG0668	transmembrane transport
Mic7113_0212	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Mic7113_0219	COG0454	-acetyltransferase
Mic7113_0222	COG2890	protein-(glutamine-N5) methyltransferase activity
Mic7113_0223	COG0009	L-threonylcarbamoyladenylate synthase
Mic7113_0224	COG2198	Histidine kinase
Mic7113_0224	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Mic7113_0224	COG0784	Response regulator, receiver
Mic7113_0224	COG2205	protein histidine kinase activity
Mic7113_0225	COG1042	CoA-binding domain protein
Mic7113_0225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Mic7113_0225	COG0045	succinate-CoA ligase (ADP-forming) activity
Mic7113_0227	COG0113	porphobilinogen synthase activity
Mic7113_0228	COG2205	protein histidine kinase activity
Mic7113_0228	COG0784	Response regulator, receiver
Mic7113_0229	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Mic7113_0230	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Mic7113_0235	COG0701	Predicted permease
Mic7113_0239	COG3118	belongs to the thioredoxin family
Mic7113_0241	COG0516	GMP reductase activity
Mic7113_0242	COG1012	belongs to the aldehyde dehydrogenase family
Mic7113_0246	COG0038	chloride channel
Mic7113_0249	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Mic7113_0250	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Mic7113_0257	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Mic7113_0259	COG0314	molybdopterin synthase activity
Mic7113_0260	COG4251	negative regulation of phosphorylation
Mic7113_0261	COG0784	Response regulator, receiver
Mic7113_0262	COG0596	Alpha beta hydrolase
Mic7113_0263	COG5002	protein histidine kinase activity
Mic7113_0263	COG0784	Response regulator, receiver
Mic7113_0263	COG2205	protein histidine kinase activity
Mic7113_0264	COG4251	negative regulation of phosphorylation
Mic7113_0269	COG1160	GTP binding
Mic7113_0271	COG2205	protein histidine kinase activity
Mic7113_0273	COG4251	negative regulation of phosphorylation
Mic7113_0274	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Mic7113_0284	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Mic7113_0285	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Mic7113_0293	COG1309	transcriptional regulator
Mic7113_0299	COG5001	Diguanylate cyclase
Mic7113_0299	COG1716	ATPase activity
Mic7113_0301	COG0006	proline dipeptidase activity
Mic7113_0306	COG2197	response regulator
Mic7113_0313	COG4249	Peptidase C14 caspase catalytic subunit p20
Mic7113_0313	COG2319	Wd-40 repeat
Mic7113_0314	COG2239	Acts as a magnesium transporter
Mic7113_0317	COG0386	Belongs to the glutathione peroxidase family
Mic7113_0320	COG0025	NhaP-type Na H and K H
Mic7113_0329	COG0180	Tryptophanyl-tRNA synthetase
Mic7113_0331	COG0521	Mo-molybdopterin cofactor biosynthetic process
Mic7113_0333	COG1404	Belongs to the peptidase S8 family
Mic7113_0333	COG4935	Belongs to the peptidase S8 family
Mic7113_0334	COG0793	Belongs to the peptidase S41A family
Mic7113_0337	COG3829	transcription factor binding
Mic7113_0339	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_0339	COG0515	serine threonine protein kinase
Mic7113_0341	COG1047	Peptidyl-prolyl cis-trans
Mic7113_0344	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Mic7113_0344	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Mic7113_0345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Mic7113_0345	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Mic7113_0346	COG0840	transmembrane signaling receptor activity
Mic7113_0346	COG2203	Gaf domain
Mic7113_0350	COG0392	lysyltransferase activity
Mic7113_0350	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Mic7113_0356	COG0515	serine threonine protein kinase
Mic7113_0356	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_0358	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Mic7113_0360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Mic7113_0361	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Mic7113_0362	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Mic7113_0365	COG1968	undecaprenyl-diphosphatase activity
Mic7113_0368	COG0321	lipoyl(octanoyl) transferase activity
Mic7113_0369	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Mic7113_0370	COG0438	transferase activity, transferring glycosyl groups
Mic7113_0372	COG1381	Involved in DNA repair and RecF pathway recombination
Mic7113_0373	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Mic7113_0374	COG0803	Belongs to the bacterial solute-binding protein 9 family
Mic7113_0375	COG1121	(ABC) transporter
Mic7113_0376	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Mic7113_0380	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Mic7113_0382	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Mic7113_0390	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Mic7113_0391	COG1234	tRNA 3'-trailer cleavage
Mic7113_0395	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Mic7113_0396	COG0577	efflux transmembrane transporter activity
Mic7113_0396	COG1136	(ABC) transporter
Mic7113_0405	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Mic7113_0406	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Mic7113_0407	COG2080	2 iron, 2 sulfur cluster binding
Mic7113_0417	COG0625	glutathione transferase activity
Mic7113_0422	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Mic7113_0423	COG0860	N-Acetylmuramoyl-L-alanine amidase
Mic7113_0423	COG3409	Peptidoglycan-binding domain 1 protein
Mic7113_0424	COG0463	Glycosyl transferase, family 2
Mic7113_0424	COG0457	Tetratricopeptide repeat
Mic7113_0429	COG2319	Wd-40 repeat
Mic7113_0429	COG1672	PFAM Archaeal ATPase
Mic7113_0431	COG3903	Transcriptional regulator
Mic7113_0431	COG2319	Wd-40 repeat
Mic7113_0432	COG1649	PFAM Uncharacterised BCR, COG1649
Mic7113_0437	COG1672	PFAM Archaeal ATPase
Mic7113_0437	COG2319	Wd-40 repeat
Mic7113_0440	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Mic7113_0442	COG0784	Response regulator, receiver
Mic7113_0442	COG2205	protein histidine kinase activity
Mic7113_0443	COG0824	Thioesterase
Mic7113_0445	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Mic7113_0445	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Mic7113_0448	COG2119	membrane
Mic7113_0449	COG2119	membrane
Mic7113_0456	COG4249	Peptidase C14 caspase catalytic subunit p20
Mic7113_0456	COG2319	Wd-40 repeat
Mic7113_0464	COG1192	Involved in chromosome partitioning
Mic7113_0469	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Mic7113_0469	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Mic7113_0470	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Mic7113_0471	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Mic7113_0478	COG1846	Transcriptional regulator
Mic7113_0479	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Mic7113_0485	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
Mic7113_0486	COG0800	Aldolase
Mic7113_0490	COG0463	Glycosyl transferase, family 2
Mic7113_0492	COG0668	transmembrane transport
Mic7113_0494	COG2912	Transglutaminase-like superfamily
Mic7113_0501	COG0859	PFAM glycosyl transferase family 9
Mic7113_0502	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Mic7113_0504	COG1515	deoxyribonuclease V activity
Mic7113_0508	COG3621	Patatin-like phospholipase
Mic7113_0509	COG3903	Transcriptional regulator
Mic7113_0509	COG2319	Wd-40 repeat
Mic7113_0516	COG2885	chlorophyll binding
Mic7113_0518	COG2885	chlorophyll binding
Mic7113_0521	COG4251	negative regulation of phosphorylation
Mic7113_0524	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Mic7113_0526	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Mic7113_0527	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Mic7113_0528	COG3118	belongs to the thioredoxin family
Mic7113_0530	COG0583	DNA-binding transcription factor activity
Mic7113_0531	COG0515	serine threonine protein kinase
Mic7113_0539	COG0531	amino acid
Mic7113_0547	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Mic7113_0549	COG1316	TRANSCRIPTIONal
Mic7113_0550	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_0557	COG1741	Belongs to the pirin family
Mic7113_0558	COG1733	regulation of RNA biosynthetic process
Mic7113_0560	COG0517	IMP dehydrogenase activity
Mic7113_0560	COG1994	Peptidase M50
Mic7113_0566	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Mic7113_0570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Mic7113_0577	COG1215	transferase activity, transferring glycosyl groups
Mic7113_0580	COG1216	Glycosyl transferase, family 2
Mic7113_0587	COG4178	(ABC) transporter
Mic7113_0591	COG0438	transferase activity, transferring glycosyl groups
Mic7113_0592	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Mic7113_0593	COG5001	Diguanylate cyclase
Mic7113_0593	COG3447	MASE1 domain protein
Mic7113_0593	COG5002	protein histidine kinase activity
Mic7113_0594	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Mic7113_0596	COG0505	Belongs to the CarA family
Mic7113_0598	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
Mic7113_0599	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Mic7113_0601	COG0596	Alpha beta hydrolase
Mic7113_0612	COG2319	Wd-40 repeat
Mic7113_0612	COG3903	Transcriptional regulator
Mic7113_0613	COG0154	amidase activity
Mic7113_0614	COG0587	DNA-directed DNA polymerase activity
Mic7113_0620	COG3657	addiction module killer protein
Mic7113_0622	COG2337	Toxic component of a toxin-antitoxin (TA) module
Mic7113_0636	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Mic7113_0640	COG4191	Histidine kinase
Mic7113_0641	COG0440	acetolactate synthase activity
Mic7113_0644	COG3659	wide pore channel activity
Mic7113_0647	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Mic7113_0653	COG0612	Peptidase, M16
Mic7113_0654	COG0612	Peptidase, M16
Mic7113_0659	COG3842	ATPase activity
Mic7113_0660	COG0210	DNA helicase
Mic7113_0665	COG0259	pyridoxamine-phosphate oxidase activity
Mic7113_0667	COG4399	Belongs to the UPF0754 family
Mic7113_0668	COG2226	methyltransferase
Mic7113_0669	COG2204	response regulator
Mic7113_0673	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Mic7113_0674	COG2022	thiamine diphosphate biosynthetic process
Mic7113_0674	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Mic7113_0684	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Mic7113_0689	COG0811	peptide transport
Mic7113_0691	COG1032	radical SAM domain protein
Mic7113_0692	COG1994	Peptidase M50
Mic7113_0700	COG0495	leucyl-tRNA aminoacylation
Mic7113_0702	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Mic7113_0706	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Mic7113_0716	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_0716	COG0515	serine threonine protein kinase
Mic7113_0718	COG1376	ErfK ybiS ycfS ynhG family protein
Mic7113_0719	COG0515	serine threonine protein kinase
Mic7113_0719	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_0721	COG1473	amidohydrolase
Mic7113_0727	COG4294	response to UV
Mic7113_0729	COG0784	Response regulator, receiver
Mic7113_0729	COG2198	Histidine kinase
Mic7113_0729	COG2205	protein histidine kinase activity
Mic7113_0730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Mic7113_0737	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Mic7113_0738	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Mic7113_0742	COG0138	bifunctional purine biosynthesis protein purh
Mic7113_0745	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Mic7113_0746	COG2267	carboxylic ester hydrolase activity
Mic7113_0750	COG1191	sigma factor activity
Mic7113_0751	COG0670	Belongs to the BI1 family
Mic7113_0754	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Mic7113_0755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Mic7113_0756	COG0512	Glutamine amidotransferase of anthranilate synthase
Mic7113_0756	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Mic7113_0760	COG0006	proline dipeptidase activity
Mic7113_0762	COG3237	CsbD-like
Mic7113_0763	COG3609	addiction module antidote protein, CC2985 family
Mic7113_0768	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Mic7113_0772	COG1606	tRNA processing
Mic7113_0774	COG4172	Belongs to the ABC transporter superfamily
Mic7113_0775	COG0542	response to heat
Mic7113_0778	COG4249	Peptidase C14 caspase catalytic subunit p20
Mic7113_0778	COG2319	Wd-40 repeat
Mic7113_0779	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Mic7113_0792	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Mic7113_0793	COG2211	Major facilitator Superfamily
Mic7113_0794	COG0438	transferase activity, transferring glycosyl groups
Mic7113_0803	COG2885	chlorophyll binding
Mic7113_0803	COG3047	cAMP biosynthetic process
Mic7113_0804	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Mic7113_0807	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Mic7113_0808	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Mic7113_0816	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Mic7113_0820	COG2815	serine threonine protein kinase
Mic7113_0820	COG0515	serine threonine protein kinase
Mic7113_0834	COG0004	ammonium transporteR
Mic7113_0851	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Mic7113_0852	COG0438	transferase activity, transferring glycosyl groups
Mic7113_0854	COG1193	negative regulation of DNA recombination
Mic7113_0861	COG1748	Saccharopine dehydrogenase
Mic7113_0863	COG1459	type II secretion system
Mic7113_0865	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Mic7113_0866	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Mic7113_0867	COG0443	Heat shock 70 kDa protein
Mic7113_0868	COG0484	heat shock protein binding
Mic7113_0870	COG1162	GTPase activity
Mic7113_0872	COG0745	RESPONSE REGULATOR receiver
Mic7113_0873	COG0483	inositol monophosphate 1-phosphatase activity
Mic7113_0878	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Mic7113_0883	COG0745	RESPONSE REGULATOR receiver
Mic7113_0883	COG2205	protein histidine kinase activity
Mic7113_0883	COG3292	Two component regulator propeller
Mic7113_0891	COG0515	serine threonine protein kinase
Mic7113_0891	COG3266	domain, Protein
Mic7113_0894	COG3266	domain, Protein
Mic7113_0894	COG1361	Conserved repeat domain
Mic7113_0894	COG2911	Protein conserved in bacteria
Mic7113_0895	COG1131	(ABC) transporter
Mic7113_0900	COG1185	polyribonucleotide nucleotidyltransferase activity
Mic7113_0901	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Mic7113_0905	COG0123	including yeast histone deacetylase and acetoin utilization protein
Mic7113_0906	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Mic7113_0907	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Mic7113_0909	COG0739	heme binding
Mic7113_0912	COG0450	alkyl hydroperoxide reductase
Mic7113_0913	COG2177	Part of the ABC transporter FtsEX involved in
Mic7113_0918	COG5001	Diguanylate cyclase
Mic7113_0918	COG4251	negative regulation of phosphorylation
Mic7113_0918	COG2203	Gaf domain
Mic7113_0918	COG3706	GGDEF domain
Mic7113_0920	COG2166	iron-sulfur cluster assembly
Mic7113_0925	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Mic7113_0929	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Mic7113_0934	COG0793	Belongs to the peptidase S41A family
Mic7113_0935	COG2319	Wd-40 repeat
Mic7113_0935	COG4249	Peptidase C14 caspase catalytic subunit p20
Mic7113_0939	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Mic7113_0940	COG0351	phosphomethylpyrimidine kinase
Mic7113_0943	COG5002	protein histidine kinase activity
Mic7113_0945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Mic7113_0946	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Mic7113_0947	COG2203	Gaf domain
Mic7113_0957	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Mic7113_0964	COG3852	Histidine kinase
Mic7113_0968	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
Mic7113_0970	COG3237	CsbD-like
Mic7113_0973	COG0556	nucleotide-excision repair
Mic7113_0979	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
Mic7113_0981	COG0123	including yeast histone deacetylase and acetoin utilization protein
Mic7113_0982	COG0284	orotidine-5'-phosphate decarboxylase activity
Mic7113_0982	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Mic7113_0989	COG0789	Transcriptional regulator
Mic7113_0992	COG0686	Belongs to the AlaDH PNT family
Mic7113_0994	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Mic7113_0994	COG2205	protein histidine kinase activity
Mic7113_0994	COG0784	Response regulator, receiver
Mic7113_0994	COG2198	Histidine kinase
Mic7113_0995	COG0724	RNA recognition motif
Mic7113_0996	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Mic7113_0997	COG2135	peptidase activity
Mic7113_1002	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Mic7113_1005	COG3937	granule-associated protein
Mic7113_1008	COG0672	)-iron permease
Mic7113_1012	COG2132	Multicopper oxidase
Mic7113_1016	COG2226	methyltransferase
Mic7113_1017	COG2720	vancomycin resistance protein
Mic7113_1018	COG1122	ATPase activity
Mic7113_1019	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Mic7113_1030	COG0515	serine threonine protein kinase
Mic7113_1032	COG2204	response regulator
Mic7113_1033	COG2205	protein histidine kinase activity
Mic7113_1033	COG0784	Response regulator, receiver
Mic7113_1034	COG0735	belongs to the Fur family
Mic7113_1035	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Mic7113_1036	COG1819	glycosyl
Mic7113_1037	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Mic7113_1041	COG0581	inorganic phosphate transmembrane transporter activity
Mic7113_1042	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Mic7113_1043	COG0438	transferase activity, transferring glycosyl groups
Mic7113_1050	COG1216	Glycosyl transferase, family 2
Mic7113_1051	COG2894	cell division
Mic7113_1057	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Mic7113_1058	COG2884	Cell division ATP-binding protein ftsE
Mic7113_1073	COG0366	Alpha amylase catalytic
Mic7113_1074	COG0587	DNA-directed DNA polymerase activity
Mic7113_1075	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_1075	COG0515	serine threonine protein kinase
Mic7113_1082	COG0336	Belongs to the RNA methyltransferase TrmD family
Mic7113_1083	COG4242	Belongs to the peptidase S51 family
Mic7113_1084	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Mic7113_1084	COG0189	ligase activity
Mic7113_1085	COG3659	wide pore channel activity
Mic7113_1087	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Mic7113_1092	COG1361	Conserved repeat domain
Mic7113_1096	COG0848	biopolymer transport protein
Mic7113_1097	COG0811	peptide transport
Mic7113_1100	COG2205	protein histidine kinase activity
Mic7113_1102	COG0745	RESPONSE REGULATOR receiver
Mic7113_1103	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Mic7113_1108	COG2201	protein-glutamate methylesterase activity
Mic7113_1110	COG1404	Belongs to the peptidase S8 family
Mic7113_1112	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Mic7113_1113	COG1131	(ABC) transporter
Mic7113_1117	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Mic7113_1121	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Mic7113_1127	COG0135	phosphoribosylanthranilate isomerase activity
Mic7113_1130	COG1994	Peptidase M50
Mic7113_1130	COG0517	IMP dehydrogenase activity
Mic7113_1131	COG0095	Lipoate-protein ligase
Mic7113_1133	COG2205	protein histidine kinase activity
Mic7113_1133	COG0784	Response regulator, receiver
Mic7113_1135	COG0174	glutamine synthetase
Mic7113_1139	COG0515	serine threonine protein kinase
Mic7113_1139	COG2815	serine threonine protein kinase
Mic7113_1146	COG4680	protein conserved in bacteria
Mic7113_1148	COG2814	Major facilitator Superfamily
Mic7113_1152	COG3185	4-Hydroxyphenylpyruvate dioxygenase
Mic7113_1155	COG0315	cyclic pyranopterin monophosphate synthase activity
Mic7113_1159	COG0728	peptidoglycan biosynthetic process
Mic7113_1160	COG5002	protein histidine kinase activity
Mic7113_1163	COG1489	DNA binding
Mic7113_1164	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Mic7113_1166	COG1132	(ABC) transporter
Mic7113_1168	COG1716	ATPase activity
Mic7113_1168	COG5001	Diguanylate cyclase
Mic7113_1170	COG4106	trans-aconitate 2-methyltransferase activity
Mic7113_1171	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Mic7113_1172	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Mic7113_1173	COG0456	acetyltransferase
Mic7113_1178	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Mic7113_1180	COG1950	PFAM Membrane protein of
Mic7113_1189	COG4636	protein conserved in cyanobacteria
Mic7113_1193	COG1754	DNA topoisomerase type I activity
Mic7113_1193	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Mic7113_1194	COG0784	Response regulator, receiver
Mic7113_1194	COG2198	Histidine kinase
Mic7113_1194	COG5002	protein histidine kinase activity
Mic7113_1196	COG1007	ATP synthesis coupled electron transport
Mic7113_1198	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Mic7113_1199	COG1408	metallophosphoesterase
Mic7113_1210	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Mic7113_1219	COG1496	oxidoreductase activity
Mic7113_1220	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Mic7113_1220	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Mic7113_1221	COG0739	heme binding
Mic7113_1229	COG5002	protein histidine kinase activity
Mic7113_1229	COG2205	protein histidine kinase activity
Mic7113_1229	COG0784	Response regulator, receiver
Mic7113_1230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Mic7113_1231	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Mic7113_1233	COG0860	N-Acetylmuramoyl-L-alanine amidase
Mic7113_1237	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Mic7113_1241	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Mic7113_1242	COG0306	phosphate transporter
Mic7113_1244	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Mic7113_1253	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Mic7113_1255	COG0784	Response regulator, receiver
Mic7113_1258	COG0840	transmembrane signaling receptor activity
Mic7113_1258	COG2203	Gaf domain
Mic7113_1259	COG0643	Histidine kinase
Mic7113_1259	COG0784	Response regulator, receiver
Mic7113_1259	COG2198	Histidine kinase
Mic7113_1263	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Mic7113_1265	COG0121	glutamine amidotransferase
Mic7113_1266	COG5635	Nacht domain
Mic7113_1266	COG2319	Wd-40 repeat
Mic7113_1269	COG4636	protein conserved in cyanobacteria
Mic7113_1270	COG2373	Large extracellular alpha-helical protein
Mic7113_1271	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Mic7113_1272	COG4149	molybdate abc transporter
Mic7113_1273	COG0725	ABC transporter, periplasmic molybdate-binding protein
Mic7113_1274	COG3585	molybdate ion transport
Mic7113_1280	COG0316	Belongs to the HesB IscA family
Mic7113_1282	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Mic7113_1284	COG5420	small protein containing a coiled-coil domain
Mic7113_1287	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Mic7113_1288	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Mic7113_1290	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Mic7113_1294	COG1104	cysteine desulfurase activity
Mic7113_1295	COG0535	radical SAM domain protein
Mic7113_1295	COG1433	Dinitrogenase iron-molybdenum cofactor
Mic7113_1296	COG1045	serine acetyltransferase
Mic7113_1298	COG0783	Belongs to the Dps family
Mic7113_1300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Mic7113_1301	COG5554	nitrogen fixation
Mic7113_1308	COG0347	Belongs to the P(II) protein family
Mic7113_1311	COG0402	S-adenosylhomocysteine deaminase activity
Mic7113_1312	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Mic7113_1313	COG0596	Alpha beta hydrolase
Mic7113_1314	COG0515	serine threonine protein kinase
Mic7113_1315	COG0363	glucosamine-6-phosphate deaminase activity
Mic7113_1316	COG2223	nitrite transmembrane transporter activity
Mic7113_1328	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
Mic7113_1330	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Mic7113_1334	COG1882	Formate acetyltransferase
Mic7113_1335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Mic7113_1337	COG1012	belongs to the aldehyde dehydrogenase family
Mic7113_1337	COG1454	alcohol dehydrogenase
Mic7113_1341	COG0735	belongs to the Fur family
Mic7113_1342	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Mic7113_1343	COG0047	phosphoribosylformylglycinamidine synthase activity
Mic7113_1345	COG2319	Wd-40 repeat
Mic7113_1346	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Mic7113_1348	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Mic7113_1349	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Mic7113_1351	COG1716	ATPase activity
Mic7113_1352	COG0363	glucosamine-6-phosphate deaminase activity
Mic7113_1355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Mic7113_1356	COG0552	protein localization to endoplasmic reticulum
Mic7113_1357	COG0745	RESPONSE REGULATOR receiver
Mic7113_1359	COG4636	protein conserved in cyanobacteria
Mic7113_1362	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Mic7113_1366	COG0632	four-way junction helicase activity
Mic7113_1367	COG0561	phosphatase activity
Mic7113_1368	COG2319	Wd-40 repeat
Mic7113_1368	COG4249	Peptidase C14 caspase catalytic subunit p20
Mic7113_1372	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Mic7113_1373	COG0515	serine threonine protein kinase
Mic7113_1373	COG3266	domain, Protein
Mic7113_1376	COG3659	wide pore channel activity
Mic7113_1377	COG3659	wide pore channel activity
Mic7113_1378	COG0640	Transcriptional regulator
Mic7113_1386	COG2082	Precorrin-8x methylmutase
Mic7113_1388	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Mic7113_1391	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Mic7113_1392	COG0187	DNA topoisomerase II activity
Mic7113_1392	COG1372	Participates in initiation and elongation during chromosome replication
Mic7113_1398	COG5398	heme oxygenase
Mic7113_1402	COG0222	ribosome binding
Mic7113_1403	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Mic7113_1404	COG0081	regulation of translation
Mic7113_1405	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Mic7113_1406	COG0250	Participates in transcription elongation, termination and antitermination
Mic7113_1407	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Mic7113_1409	COG0335	large ribosomal subunit rRNA binding
Mic7113_1410	COG3659	wide pore channel activity
Mic7113_1411	COG3659	wide pore channel activity
Mic7113_1412	COG3659	wide pore channel activity
Mic7113_1413	COG0704	Plays a role in the regulation of phosphate uptake
Mic7113_1414	COG5002	protein histidine kinase activity
Mic7113_1415	COG0745	RESPONSE REGULATOR receiver
Mic7113_1416	COG1402	creatininase
Mic7113_1417	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Mic7113_1418	COG0745	RESPONSE REGULATOR receiver
Mic7113_1421	COG3239	Fatty acid desaturase
Mic7113_1423	COG0493	'glutamate synthase
Mic7113_1425	COG0067	glutamate synthase
Mic7113_1425	COG0070	glutamate synthase
Mic7113_1425	COG0069	glutamate synthase activity
Mic7113_1435	COG0616	signal peptide processing
Mic7113_1436	COG1304	FMN binding
Mic7113_1437	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Mic7113_1438	COG3409	Peptidoglycan-binding domain 1 protein
Mic7113_1438	COG3773	Cell wall hydrolase
Mic7113_1439	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Mic7113_1441	COG1959	2 iron, 2 sulfur cluster binding
Mic7113_1447	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Mic7113_1449	COG0745	RESPONSE REGULATOR receiver
Mic7113_1450	COG5002	protein histidine kinase activity
Mic7113_1451	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Mic7113_1454	COG0515	serine threonine protein kinase
Mic7113_1459	COG0537	adenosine 5'-monophosphoramidase activity
Mic7113_1460	COG0606	chelatase, subunit chli
Mic7113_1462	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Mic7113_1463	COG0574	Belongs to the PEP-utilizing enzyme family
Mic7113_1463	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Mic7113_1466	COG0484	heat shock protein binding
Mic7113_1467	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Mic7113_1469	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Mic7113_1472	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Mic7113_1476	COG2852	Protein conserved in bacteria
Mic7113_1478	COG2084	Dehydrogenase
Mic7113_1479	COG0039	L-malate dehydrogenase activity
Mic7113_1483	COG3047	cAMP biosynthetic process
Mic7113_1483	COG2885	chlorophyll binding
Mic7113_1486	COG1187	pseudouridine synthase activity
Mic7113_1488	COG3266	domain, Protein
Mic7113_1488	COG0515	serine threonine protein kinase
Mic7113_1491	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Mic7113_1495	COG4636	protein conserved in cyanobacteria
Mic7113_1496	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Mic7113_1498	COG0745	RESPONSE REGULATOR receiver
Mic7113_1500	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Mic7113_1501	COG0271	Belongs to the BolA IbaG family
Mic7113_1503	COG1404	Belongs to the peptidase S8 family
Mic7113_1503	COG4935	Belongs to the peptidase S8 family
Mic7113_1505	COG4689	acetoacetate decarboxylase
Mic7113_1507	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Mic7113_1510	COG1253	flavin adenine dinucleotide binding
Mic7113_1511	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Mic7113_1512	COG0542	response to heat
Mic7113_1516	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Mic7113_1520	COG0170	dolichyl monophosphate biosynthetic process
Mic7113_1521	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Mic7113_1522	COG2197	response regulator
Mic7113_1525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Mic7113_1527	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
Mic7113_1533	COG2205	protein histidine kinase activity
Mic7113_1533	COG2202	Pas domain
Mic7113_1542	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Mic7113_1547	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Mic7113_1548	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Mic7113_1551	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Mic7113_1556	COG4636	protein conserved in cyanobacteria
Mic7113_1559	COG1136	(ABC) transporter
Mic7113_1559	COG0577	efflux transmembrane transporter activity
Mic7113_1561	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Mic7113_1569	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Mic7113_1572	COG1012	belongs to the aldehyde dehydrogenase family
Mic7113_1573	COG0237	dephospho-CoA kinase activity
Mic7113_1574	COG4636	protein conserved in cyanobacteria
Mic7113_1576	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Mic7113_1585	COG3903	Transcriptional regulator
Mic7113_1585	COG2319	Wd-40 repeat
Mic7113_1588	COG5398	heme oxygenase
Mic7113_1589	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
Mic7113_1593	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Mic7113_1594	COG0501	Belongs to the peptidase M48B family
Mic7113_1597	COG4974	Belongs to the 'phage' integrase family
Mic7113_1601	COG0110	maltose O-acetyltransferase activity
Mic7113_1603	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Mic7113_1604	COG1690	Belongs to the RtcB family
Mic7113_1605	COG2226	methyltransferase
Mic7113_1610	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Mic7113_1610	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Mic7113_1616	COG0515	serine threonine protein kinase
Mic7113_1616	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_1620	COG1077	Cell shape determining protein MreB Mrl
Mic7113_1621	COG0629	single-stranded DNA binding
Mic7113_1624	COG0475	glutathione-regulated potassium exporter activity
Mic7113_1625	COG0860	N-Acetylmuramoyl-L-alanine amidase
Mic7113_1626	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Mic7113_1628	COG0142	geranyltranstransferase activity
Mic7113_1635	COG5001	Diguanylate cyclase
Mic7113_1635	COG1716	ATPase activity
Mic7113_1636	COG0398	Pfam SNARE associated Golgi protein
Mic7113_1639	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Mic7113_1641	COG0573	inorganic phosphate transmembrane transporter activity
Mic7113_1642	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Mic7113_1650	COG0848	biopolymer transport protein
Mic7113_1651	COG0811	peptide transport
Mic7113_1652	COG4771	TonB-dependent receptor
Mic7113_1657	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Mic7113_1658	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Mic7113_1659	COG1120	ATPase activity
Mic7113_1663	COG0640	Transcriptional regulator
Mic7113_1664	COG2226	methyltransferase
Mic7113_1666	COG0515	serine threonine protein kinase
Mic7113_1668	COG0745	RESPONSE REGULATOR receiver
Mic7113_1668	COG3292	Two component regulator propeller
Mic7113_1668	COG2205	protein histidine kinase activity
Mic7113_1673	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Mic7113_1674	COG0798	PFAM Bile acid sodium symporter
Mic7113_1675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Mic7113_1676	COG0640	Transcriptional regulator
Mic7113_1679	COG5002	protein histidine kinase activity
Mic7113_1680	COG0784	Response regulator, receiver
Mic7113_1683	COG0484	heat shock protein binding
Mic7113_1686	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Mic7113_1690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Mic7113_1708	COG0352	thiamine-phosphate diphosphorylase activity
Mic7113_1711	COG3852	Histidine kinase
Mic7113_1712	COG0745	RESPONSE REGULATOR receiver
Mic7113_1713	COG2205	protein histidine kinase activity
Mic7113_1714	COG2875	Belongs to the precorrin methyltransferase family
Mic7113_1725	COG0515	serine threonine protein kinase
Mic7113_1725	COG2815	serine threonine protein kinase
Mic7113_1726	COG4585	Histidine kinase
Mic7113_1727	COG2197	response regulator
Mic7113_1733	COG1266	CAAX protease self-immunity
Mic7113_1743	COG2124	cytochrome p450
Mic7113_1746	COG0076	glutamate decarboxylase activity
Mic7113_1750	COG1960	acyl-CoA dehydrogenase activity
Mic7113_1752	COG1250	3-hydroxyacyl-CoA dehydrogenase
Mic7113_1755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Mic7113_1756	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Mic7113_1757	COG0736	holo-[acyl-carrier-protein] synthase activity
Mic7113_1760	COG0736	holo-[acyl-carrier-protein] synthase activity
Mic7113_1762	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Mic7113_1765	COG2217	Heavy metal translocating P-type atpase
Mic7113_1774	COG4251	negative regulation of phosphorylation
Mic7113_1774	COG5001	Diguanylate cyclase
Mic7113_1774	COG3706	GGDEF domain
Mic7113_1774	COG2203	Gaf domain
Mic7113_1775	COG0784	Response regulator, receiver
Mic7113_1775	COG2205	protein histidine kinase activity
Mic7113_1775	COG2198	Histidine kinase
Mic7113_1775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Mic7113_1776	COG1028	Short-chain dehydrogenase reductase Sdr
Mic7113_1780	COG2319	Wd-40 repeat
Mic7113_1780	COG3903	Transcriptional regulator
Mic7113_1782	COG0514	ATP-dependent DNA helicase (RecQ)
Mic7113_1787	COG2319	Wd-40 repeat
Mic7113_1787	COG1672	PFAM Archaeal ATPase
Mic7113_1796	COG1028	Short-chain dehydrogenase reductase Sdr
Mic7113_1801	COG1040	competence protein
Mic7113_1803	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_1803	COG0515	serine threonine protein kinase
Mic7113_1806	COG1266	CAAX protease self-immunity
Mic7113_1810	COG2076	Multidrug Resistance protein
Mic7113_1812	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Mic7113_1813	COG0697	spore germination
Mic7113_1817	COG1446	asparaginase
Mic7113_1821	COG1196	nuclear chromosome segregation
Mic7113_1824	COG1595	DNA-templated transcription, initiation
Mic7113_1827	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Mic7113_1828	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Mic7113_1829	COG3903	Transcriptional regulator
Mic7113_1829	COG2319	Wd-40 repeat
Mic7113_1830	COG2205	protein histidine kinase activity
Mic7113_1831	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Mic7113_1832	COG0435	Glutathione S-transferase
Mic7113_1833	COG0649	NAD binding
Mic7113_1834	COG2124	cytochrome p450
Mic7113_1836	COG0390	transport system, permease component
Mic7113_1839	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_1839	COG0515	serine threonine protein kinase
Mic7113_1841	COG3239	Fatty acid desaturase
Mic7113_1854	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Mic7113_1855	COG2205	protein histidine kinase activity
Mic7113_1857	COG0489	protein tyrosine kinase activity
Mic7113_1860	COG2226	methyltransferase
Mic7113_1862	COG1215	transferase activity, transferring glycosyl groups
Mic7113_1867	COG0726	polysaccharide deacetylase
Mic7113_1870	COG0628	permease
Mic7113_1874	COG0628	permease
Mic7113_1876	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Mic7113_1877	COG0631	protein serine/threonine phosphatase activity
Mic7113_1878	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Mic7113_1879	COG3937	granule-associated protein
Mic7113_1880	COG0515	serine threonine protein kinase
Mic7113_1880	COG2815	serine threonine protein kinase
Mic7113_1882	COG0517	IMP dehydrogenase activity
Mic7113_1882	COG0617	tRNA 3'-terminal CCA addition
Mic7113_1882	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Mic7113_1885	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Mic7113_1888	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Mic7113_1890	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Mic7113_1893	COG2205	protein histidine kinase activity
Mic7113_1893	COG3292	Two component regulator propeller
Mic7113_1893	COG0745	RESPONSE REGULATOR receiver
Mic7113_1894	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_1894	COG0515	serine threonine protein kinase
Mic7113_1900	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Mic7113_1902	COG0643	Histidine kinase
Mic7113_1902	COG0784	Response regulator, receiver
Mic7113_1902	COG2198	Histidine kinase
Mic7113_1903	COG0840	transmembrane signaling receptor activity
Mic7113_1903	COG2203	Gaf domain
Mic7113_1908	COG0830	nickel cation binding
Mic7113_1909	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
Mic7113_1914	COG2082	Precorrin-8x methylmutase
Mic7113_1917	COG0439	Biotin carboxylase
Mic7113_1920	COG0515	serine threonine protein kinase
Mic7113_1923	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Mic7113_1924	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Mic7113_1937	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Mic7113_1943	COG1429	ligase activity, forming nitrogen-metal bonds
Mic7113_1954	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Mic7113_1955	COG0431	NADPH-dependent FMN reductase
Mic7113_1960	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Mic7113_1962	COG0330	HflC and HflK could
Mic7113_1972	COG2124	cytochrome p450
Mic7113_1973	COG1032	radical SAM domain protein
Mic7113_1976	COG4638	Rieske (2fe-2S)
Mic7113_1977	COG0156	8-amino-7-oxononanoate synthase activity
Mic7113_1985	COG0861	Integral membrane protein TerC family
Mic7113_1986	COG0105	UTP biosynthetic process
Mic7113_1987	COG1181	Belongs to the D-alanine--D-alanine ligase family
Mic7113_1989	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Mic7113_1995	COG0509	glycine decarboxylation via glycine cleavage system
Mic7113_2002	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Mic7113_2003	COG0574	Belongs to the PEP-utilizing enzyme family
Mic7113_2003	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Mic7113_2005	COG0316	Belongs to the HesB IscA family
Mic7113_2008	COG0501	Belongs to the peptidase M48B family
Mic7113_2016	COG0561	phosphatase activity
Mic7113_2017	COG0018	arginyl-trna synthetase
Mic7113_2018	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Mic7113_2020	COG0432	Pfam Uncharacterised protein family UPF0047
Mic7113_2023	COG5002	protein histidine kinase activity
Mic7113_2024	COG0745	RESPONSE REGULATOR receiver
Mic7113_2061	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
Mic7113_2076	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Mic7113_2080	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Mic7113_2084	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Mic7113_2086	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Mic7113_2087	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Mic7113_2088	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Mic7113_2089	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Mic7113_2091	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Mic7113_2093	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Mic7113_2095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Mic7113_2096	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Mic7113_2097	COG0511	ligase activity, forming carbon-carbon bonds
Mic7113_2098	COG0640	Transcriptional regulator
Mic7113_2102	COG0442	prolyl-tRNA aminoacylation
Mic7113_2103	COG2154	pterin-4-alpha-carbinolamine dehydratase
Mic7113_2111	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Mic7113_2115	COG1285	pathogenesis
Mic7113_2119	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Mic7113_2146	COG1575	Belongs to the MenA family. Type 1 subfamily
Mic7113_2147	COG4948	Mandelate Racemase Muconate Lactonizing
Mic7113_2148	COG0318	PFAM AMP-dependent synthetase and ligase
Mic7113_2152	COG0667	Aldo Keto reductase
Mic7113_2154	COG0745	RESPONSE REGULATOR receiver
Mic7113_2160	COG0432	Pfam Uncharacterised protein family UPF0047
Mic7113_2162	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Mic7113_2168	COG4372	Transposase
Mic7113_2169	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Mic7113_2170	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Mic7113_2171	COG0131	Imidazoleglycerol-phosphate dehydratase
Mic7113_2172	COG3903	Transcriptional regulator
Mic7113_2172	COG2319	Wd-40 repeat
Mic7113_2182	COG0542	response to heat
Mic7113_2186	COG0330	HflC and HflK could
Mic7113_2187	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Mic7113_2188	COG0149	triose-phosphate isomerase activity
Mic7113_2192	COG1070	Carbohydrate kinase
Mic7113_2197	COG0235	Class ii aldolase
Mic7113_2198	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
Mic7113_2204	COG2205	protein histidine kinase activity
Mic7113_2204	COG2198	Histidine kinase
Mic7113_2204	COG0784	Response regulator, receiver
Mic7113_2210	COG0484	heat shock protein binding
Mic7113_2217	COG1401	restriction endodeoxyribonuclease activity
Mic7113_2218	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Mic7113_2219	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
Mic7113_2220	COG0483	inositol monophosphate 1-phosphatase activity
Mic7113_2221	COG0628	permease
Mic7113_2222	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Mic7113_2223	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Mic7113_2227	COG2203	Gaf domain
Mic7113_2227	COG3706	GGDEF domain
Mic7113_2227	COG4251	negative regulation of phosphorylation
Mic7113_2227	COG5001	Diguanylate cyclase
Mic7113_2238	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Mic7113_2241	COG0438	transferase activity, transferring glycosyl groups
Mic7113_2242	COG0438	transferase activity, transferring glycosyl groups
Mic7113_2243	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Mic7113_2246	COG0668	transmembrane transport
Mic7113_2256	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Mic7113_2256	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Mic7113_2258	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Mic7113_2259	COG0129	dihydroxy-acid dehydratase activity
Mic7113_2263	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Mic7113_2271	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Mic7113_2272	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
Mic7113_2273	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Mic7113_2274	COG2205	protein histidine kinase activity
Mic7113_2275	COG0148	phosphopyruvate hydratase activity
Mic7113_2276	COG0346	lactoylglutathione lyase activity
Mic7113_2277	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Mic7113_2278	COG1028	Short-chain dehydrogenase reductase Sdr
Mic7113_2279	COG4221	oxidoreductase activity
Mic7113_2280	COG0492	ferredoxin-NADP+ reductase activity
Mic7113_2282	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Mic7113_2284	COG0697	spore germination
Mic7113_2286	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Mic7113_2288	COG0483	inositol monophosphate 1-phosphatase activity
Mic7113_2289	COG0484	heat shock protein binding
Mic7113_2290	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Mic7113_2291	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Mic7113_2292	COG0515	serine threonine protein kinase
Mic7113_2292	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_2296	COG0752	glycyl-tRNA synthetase alpha subunit
Mic7113_2302	COG0193	aminoacyl-tRNA hydrolase activity
Mic7113_2303	COG1672	PFAM Archaeal ATPase
Mic7113_2304	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Mic7113_2312	COG5002	protein histidine kinase activity
Mic7113_2312	COG2198	Histidine kinase
Mic7113_2312	COG0784	Response regulator, receiver
Mic7113_2314	COG5002	protein histidine kinase activity
Mic7113_2314	COG5001	Diguanylate cyclase
Mic7113_2314	COG3447	MASE1 domain protein
Mic7113_2321	COG3240	lipase activity
Mic7113_2323	COG0681	Belongs to the peptidase S26 family
Mic7113_2325	COG0284	orotidine-5'-phosphate decarboxylase activity
Mic7113_2326	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Mic7113_2328	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Mic7113_2332	COG0515	serine threonine protein kinase
Mic7113_2332	COG2815	serine threonine protein kinase
Mic7113_2334	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Mic7113_2336	COG1850	ribulose-bisphosphate carboxylase activity
Mic7113_2338	COG4451	ribulose bisphosphate carboxylase, small
Mic7113_2340	COG4451	ribulose bisphosphate carboxylase, small
Mic7113_2340	COG0464	growth
Mic7113_2344	COG1222	aaa ATPase
Mic7113_2348	COG3266	domain, Protein
Mic7113_2348	COG0515	serine threonine protein kinase
Mic7113_2349	COG0484	heat shock protein binding
Mic7113_2350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Mic7113_2359	COG0287	Prephenate dehydrogenase
Mic7113_2360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Mic7113_2361	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Mic7113_2362	COG3128	pkhd-type hydroxylase
Mic7113_2364	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Mic7113_2366	COG0443	Heat shock 70 kDa protein
Mic7113_2370	COG0318	PFAM AMP-dependent synthetase and ligase
Mic7113_2371	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Mic7113_2374	COG2091	lysine biosynthetic process via aminoadipic acid
Mic7113_2380	COG3903	Transcriptional regulator
Mic7113_2380	COG2319	Wd-40 repeat
Mic7113_2381	COG1403	HNH endonuclease
Mic7113_2382	COG0561	phosphatase activity
Mic7113_2386	COG0783	Belongs to the Dps family
Mic7113_2388	COG0783	Belongs to the Dps family
Mic7113_2390	COG1505	serine-type exopeptidase activity
Mic7113_2392	COG0557	exoribonuclease II activity
Mic7113_2393	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Mic7113_2394	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Mic7113_2396	COG0303	'Molybdopterin
Mic7113_2397	COG0515	serine threonine protein kinase
Mic7113_2397	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_2398	COG0072	phenylalanine-tRNA ligase activity
Mic7113_2398	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Mic7113_2400	COG0515	serine threonine protein kinase
Mic7113_2401	COG3266	domain, Protein
Mic7113_2401	COG0515	serine threonine protein kinase
Mic7113_2402	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Mic7113_2404	COG3546	catalase activity
Mic7113_2405	COG0515	serine threonine protein kinase
Mic7113_2405	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_2408	COG4251	negative regulation of phosphorylation
Mic7113_2408	COG3706	GGDEF domain
Mic7113_2408	COG2203	Gaf domain
Mic7113_2408	COG5001	Diguanylate cyclase
Mic7113_2409	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Mic7113_2412	COG0745	RESPONSE REGULATOR receiver
Mic7113_2421	COG0745	RESPONSE REGULATOR receiver
Mic7113_2423	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Mic7113_2425	COG0312	modulator of DNA gyrase
Mic7113_2433	COG5592	hemerythrin HHE cation binding domain
Mic7113_2435	COG2205	protein histidine kinase activity
Mic7113_2435	COG0784	Response regulator, receiver
Mic7113_2435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Mic7113_2435	COG2198	Histidine kinase
Mic7113_2446	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Mic7113_2450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Mic7113_2450	COG2022	thiamine diphosphate biosynthetic process
Mic7113_2451	COG2205	protein histidine kinase activity
Mic7113_2451	COG2202	Pas domain
Mic7113_2452	COG0784	Response regulator, receiver
Mic7113_2453	COG5001	Diguanylate cyclase
Mic7113_2454	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Mic7113_2455	COG4245	von Willebrand factor, type A
Mic7113_2459	COG0596	Alpha beta hydrolase
Mic7113_2467	COG0288	reversible hydration of carbon dioxide
Mic7113_2468	COG0277	FAD linked oxidase domain protein
Mic7113_2473	COG1333	cytochrome c biogenesis protein
Mic7113_2475	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Mic7113_2480	COG0312	modulator of DNA gyrase
Mic7113_2484	COG2319	Wd-40 repeat
Mic7113_2484	COG3903	Transcriptional regulator
Mic7113_2493	COG2319	Wd-40 repeat
Mic7113_2493	COG1672	PFAM Archaeal ATPase
Mic7113_2498	COG0653	protein targeting
Mic7113_2512	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Mic7113_2514	COG0693	protein deglycase activity
Mic7113_2515	COG0157	Belongs to the NadC ModD family
Mic7113_2521	COG1028	Short-chain dehydrogenase reductase Sdr
Mic7113_2522	COG1028	Short-chain dehydrogenase reductase Sdr
Mic7113_2528	COG3655	Transcriptional regulator
Mic7113_2530	COG0534	Mate efflux family protein
Mic7113_2534	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Mic7113_2536	COG0515	serine threonine protein kinase
Mic7113_2542	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Mic7113_2542	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Mic7113_2545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Mic7113_2546	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Mic7113_2546	COG1116	anion transmembrane transporter activity
Mic7113_2547	COG1116	anion transmembrane transporter activity
Mic7113_2553	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Mic7113_2554	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Mic7113_2558	COG0110	maltose O-acetyltransferase activity
Mic7113_2567	COG1215	transferase activity, transferring glycosyl groups
Mic7113_2573	COG4191	Histidine kinase
Mic7113_2582	COG0564	pseudouridine synthase activity
Mic7113_2583	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Mic7113_2591	COG0237	dephospho-CoA kinase activity
Mic7113_2592	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Mic7113_2593	COG1413	lyase activity
Mic7113_2597	COG0784	Response regulator, receiver
Mic7113_2597	COG2205	protein histidine kinase activity
Mic7113_2601	COG0513	Belongs to the DEAD box helicase family
Mic7113_2603	COG1476	TRANSCRIPTIONal
Mic7113_2628	COG4636	protein conserved in cyanobacteria
Mic7113_2634	COG2264	protein methyltransferase activity
Mic7113_2635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Mic7113_2640	COG0515	serine threonine protein kinase
Mic7113_2640	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_2645	COG0469	pyruvate kinase activity
Mic7113_2653	COG1872	DUF167
Mic7113_2654	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Mic7113_2655	COG1132	(ABC) transporter
Mic7113_2656	COG0300	oxidoreductase activity
Mic7113_2658	COG1028	Short-chain dehydrogenase reductase Sdr
Mic7113_2675	COG0515	serine threonine protein kinase
Mic7113_2675	COG2815	serine threonine protein kinase
Mic7113_2678	COG0501	Belongs to the peptidase M48B family
Mic7113_2684	COG1012	belongs to the aldehyde dehydrogenase family
Mic7113_2689	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Mic7113_2696	COG5002	protein histidine kinase activity
Mic7113_2701	COG0724	RNA recognition motif
Mic7113_2702	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Mic7113_2704	COG1562	ergosterol biosynthetic process
Mic7113_2705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Mic7113_2705	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Mic7113_2707	COG2201	protein-glutamate methylesterase activity
Mic7113_2710	COG0835	chemotaxis
Mic7113_2713	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Mic7113_2716	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Mic7113_2724	COG4948	Mandelate Racemase Muconate Lactonizing
Mic7113_2725	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Mic7113_2728	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Mic7113_2732	COG1063	alcohol dehydrogenase
Mic7113_2734	COG2205	protein histidine kinase activity
Mic7113_2734	COG2202	Pas domain
Mic7113_2736	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Mic7113_2737	COG0438	transferase activity, transferring glycosyl groups
Mic7113_2740	COG2267	carboxylic ester hydrolase activity
Mic7113_2747	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Mic7113_2748	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Mic7113_2757	COG0411	ABC transporter
Mic7113_2763	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_2764	COG0829	nickel cation binding
Mic7113_2765	COG0831	urea catabolic process
Mic7113_2767	COG0832	Belongs to the urease beta subunit family
Mic7113_2771	COG0804	urea catabolic process
Mic7113_2773	COG1653	transport
Mic7113_2775	COG0395	ABC-type sugar transport system, permease component
Mic7113_2776	COG3264	Mechanosensitive ion channel
Mic7113_2776	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Mic7113_2777	COG1316	TRANSCRIPTIONal
Mic7113_2784	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Mic7113_2785	COG2205	protein histidine kinase activity
Mic7113_2785	COG0784	Response regulator, receiver
Mic7113_2789	COG0584	glycerophosphoryl diester phosphodiesterase
Mic7113_2792	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Mic7113_2797	COG0430	RNA-3'-phosphate cyclase activity
Mic7113_2803	COG0484	heat shock protein binding
Mic7113_2805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Mic7113_2806	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Mic7113_2808	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Mic7113_2810	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Mic7113_2812	COG2319	Wd-40 repeat
Mic7113_2812	COG1672	PFAM Archaeal ATPase
Mic7113_2813	COG1672	PFAM Archaeal ATPase
Mic7113_2813	COG2319	Wd-40 repeat
Mic7113_2814	COG1672	PFAM Archaeal ATPase
Mic7113_2814	COG2319	Wd-40 repeat
Mic7113_2822	COG0714	Associated with various cellular activities
Mic7113_2824	COG3903	Transcriptional regulator
Mic7113_2824	COG2319	Wd-40 repeat
Mic7113_2828	COG5002	protein histidine kinase activity
Mic7113_2828	COG0784	Response regulator, receiver
Mic7113_2829	COG4251	negative regulation of phosphorylation
Mic7113_2833	COG0167	dihydroorotate dehydrogenase activity
Mic7113_2835	COG0745	RESPONSE REGULATOR receiver
Mic7113_2842	COG0646	methionine synthase
Mic7113_2842	COG1410	methionine synthase
Mic7113_2847	COG1473	amidohydrolase
Mic7113_2848	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Mic7113_2849	COG3266	domain, Protein
Mic7113_2849	COG0515	serine threonine protein kinase
Mic7113_2851	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Mic7113_2859	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Mic7113_2860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Mic7113_2861	COG2376	Dihydroxyacetone kinase
Mic7113_2863	COG0270	DNA (cytosine-5-)-methyltransferase activity
Mic7113_2869	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Mic7113_2870	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Mic7113_2873	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
Mic7113_2874	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Mic7113_2875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Mic7113_2880	COG0589	response to stress
Mic7113_2882	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Mic7113_2888	COG3659	wide pore channel activity
Mic7113_2889	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
Mic7113_2891	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Mic7113_2895	COG4251	negative regulation of phosphorylation
Mic7113_2895	COG5001	Diguanylate cyclase
Mic7113_2895	COG3706	GGDEF domain
Mic7113_2895	COG2203	Gaf domain
Mic7113_2899	COG0463	Glycosyl transferase, family 2
Mic7113_2902	COG1091	dTDP-4-dehydrorhamnose reductase activity
Mic7113_2905	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Mic7113_2905	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Mic7113_2910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Mic7113_2912	COG2124	cytochrome p450
Mic7113_2914	COG3956	TIGRFAM MazG family protein
Mic7113_2917	COG1295	ribonuclease BN
Mic7113_2917	COG1959	2 iron, 2 sulfur cluster binding
Mic7113_2919	COG5002	protein histidine kinase activity
Mic7113_2921	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Mic7113_2932	COG4251	negative regulation of phosphorylation
Mic7113_2933	COG2129	metallophosphoesterase
Mic7113_2936	COG1253	flavin adenine dinucleotide binding
Mic7113_2937	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Mic7113_2943	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Mic7113_2945	COG0025	NhaP-type Na H and K H
Mic7113_2947	COG3437	response regulator, receiver
Mic7113_2948	COG5002	protein histidine kinase activity
Mic7113_2948	COG0784	Response regulator, receiver
Mic7113_2949	COG0784	Response regulator, receiver
Mic7113_2949	COG2205	protein histidine kinase activity
Mic7113_2950	COG0435	Glutathione S-transferase
Mic7113_2951	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Mic7113_2952	COG0457	Tetratricopeptide repeat
Mic7113_2955	COG2255	four-way junction helicase activity
Mic7113_2956	COG0107	imidazoleglycerol-phosphate synthase activity
Mic7113_2960	COG0643	Histidine kinase
Mic7113_2960	COG0784	Response regulator, receiver
Mic7113_2960	COG2198	Histidine kinase
Mic7113_2960	COG0643	Histidine kinase
Mic7113_2960	COG0784	Response regulator, receiver
Mic7113_2960	COG2198	Histidine kinase
Mic7113_2961	COG2385	sporulation resulting in formation of a cellular spore
Mic7113_2961	COG2247	cell wall binding repeat
Mic7113_2964	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Mic7113_2970	COG0297	glycogen (starch) synthase activity
Mic7113_2978	COG2124	cytochrome p450
Mic7113_2979	COG2124	cytochrome p450
Mic7113_2981	COG0745	RESPONSE REGULATOR receiver
Mic7113_2982	COG1366	Belongs to the anti-sigma-factor antagonist family
Mic7113_2986	COG2205	protein histidine kinase activity
Mic7113_2992	COG3629	intracellular signal transduction
Mic7113_2992	COG3903	Transcriptional regulator
Mic7113_2996	COG3659	wide pore channel activity
Mic7113_3010	COG3659	wide pore channel activity
Mic7113_3013	COG0113	porphobilinogen synthase activity
Mic7113_3015	COG1121	(ABC) transporter
Mic7113_3016	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Mic7113_3021	COG0523	cobalamin synthesis protein
Mic7113_3022	COG0302	gtp cyclohydrolase
Mic7113_3023	COG0523	cobalamin synthesis protein
Mic7113_3026	COG4451	ribulose bisphosphate carboxylase, small
Mic7113_3026	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Mic7113_3027	COG0215	cysteine-tRNA ligase activity
Mic7113_3032	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Mic7113_3034	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Mic7113_3050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Mic7113_3051	COG1845	cytochrome c oxidase, subunit III
Mic7113_3066	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Mic7113_3067	COG3259	Nickel-dependent hydrogenase
Mic7113_3070	COG0375	protein maturation
Mic7113_3071	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Mic7113_3072	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Mic7113_3073	COG0298	carbon dioxide binding
Mic7113_3074	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Mic7113_3074	COG1013	pyruvate-flavodoxin oxidoreductase activity
Mic7113_3074	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Mic7113_3074	COG0674	pyruvate-flavodoxin oxidoreductase activity
Mic7113_3078	COG0205	6-phosphofructokinase activity
Mic7113_3081	COG4941	Belongs to the sigma-70 factor family
Mic7113_3082	COG3795	YCII-related domain
Mic7113_3090	COG3848	Pyruvate phosphate dikinase
Mic7113_3090	COG0574	Belongs to the PEP-utilizing enzyme family
Mic7113_3094	COG0745	RESPONSE REGULATOR receiver
Mic7113_3095	COG0745	RESPONSE REGULATOR receiver
Mic7113_3096	COG4251	negative regulation of phosphorylation
Mic7113_3097	COG5002	protein histidine kinase activity
Mic7113_3098	COG0745	RESPONSE REGULATOR receiver
Mic7113_3104	COG0501	Belongs to the peptidase M48B family
Mic7113_3106	COG2010	Cytochrome c
Mic7113_3108	COG4771	TonB-dependent receptor
Mic7113_3109	COG2807	transmembrane transport
Mic7113_3116	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Mic7113_3123	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Mic7113_3137	COG0523	cobalamin synthesis protein
Mic7113_3140	COG1136	(ABC) transporter
Mic7113_3144	COG2815	serine threonine protein kinase
Mic7113_3144	COG0515	serine threonine protein kinase
Mic7113_3145	COG0626	cystathionine gamma-synthase activity
Mic7113_3147	COG5634	Uncharacterized conserved protein (DUF2278)
Mic7113_3148	COG1691	(AIR) carboxylase
Mic7113_3150	COG0747	negative chemotaxis
Mic7113_3160	COG1136	(ABC) transporter
Mic7113_3165	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Mic7113_3166	COG1028	Short-chain dehydrogenase reductase Sdr
Mic7113_3169	COG0613	PHP domain protein
Mic7113_3175	COG4636	protein conserved in cyanobacteria
Mic7113_3187	COG0508	dehydrogenase complex catalyzes the overall conversion of
Mic7113_3193	COG1022	Amp-dependent synthetase and ligase
Mic7113_3196	COG1051	belongs to the nudix hydrolase family
Mic7113_3198	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Mic7113_3205	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Mic7113_3210	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Mic7113_3213	COG3118	belongs to the thioredoxin family
Mic7113_3215	COG0312	modulator of DNA gyrase
Mic7113_3218	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Mic7113_3218	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Mic7113_3223	COG0463	Glycosyl transferase, family 2
Mic7113_3229	COG0156	8-amino-7-oxononanoate synthase activity
Mic7113_3232	COG0772	Belongs to the SEDS family
Mic7113_3236	COG0237	dephospho-CoA kinase activity
Mic7113_3236	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Mic7113_3237	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Mic7113_3241	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Mic7113_3242	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Mic7113_3243	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Mic7113_3244	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Mic7113_3245	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Mic7113_3246	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Mic7113_3247	COG0356	it plays a direct role in the translocation of protons across the membrane
Mic7113_3249	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Mic7113_3252	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Mic7113_3254	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Mic7113_3255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Mic7113_3260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Mic7113_3261	COG0003	Pfam Anion-transporting ATPase
Mic7113_3286	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Mic7113_3289	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Mic7113_3301	COG0166	Belongs to the GPI family
Mic7113_3302	COG0745	RESPONSE REGULATOR receiver
Mic7113_3303	COG2205	protein histidine kinase activity
Mic7113_3314	COG3344	reverse transcriptase
Mic7113_3317	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Mic7113_3318	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Mic7113_3320	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Mic7113_3321	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Mic7113_3322	COG2223	nitrite transmembrane transporter activity
Mic7113_3331	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Mic7113_3332	COG2894	cell division
Mic7113_3333	COG0850	regulation of cytokinetic process
Mic7113_3340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Mic7113_3343	COG2319	Wd-40 repeat
Mic7113_3343	COG3903	Transcriptional regulator
Mic7113_3345	COG4603	Belongs to the binding-protein-dependent transport system permease family
Mic7113_3346	COG1079	Belongs to the binding-protein-dependent transport system permease family
Mic7113_3349	COG3845	ABC transporter
Mic7113_3351	COG1335	isochorismatase
Mic7113_3352	COG3659	wide pore channel activity
Mic7113_3356	COG1404	Belongs to the peptidase S8 family
Mic7113_3357	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Mic7113_3360	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Mic7113_3361	COG1518	maintenance of DNA repeat elements
Mic7113_3362	COG1468	defense response to virus
Mic7113_3362	COG1518	maintenance of DNA repeat elements
Mic7113_3370	COG0515	serine threonine protein kinase
Mic7113_3370	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_3372	COG0133	tryptophan synthase activity
Mic7113_3375	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Mic7113_3377	COG0784	Response regulator, receiver
Mic7113_3377	COG2205	protein histidine kinase activity
Mic7113_3382	COG1653	transport
Mic7113_3383	COG1175	transmembrane transport
Mic7113_3385	COG3842	ATPase activity
Mic7113_3386	COG3852	Histidine kinase
Mic7113_3387	COG0745	RESPONSE REGULATOR receiver
Mic7113_3389	COG0745	RESPONSE REGULATOR receiver
Mic7113_3390	COG3659	wide pore channel activity
Mic7113_3391	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Mic7113_3397	COG2095	MarC family integral membrane protein
Mic7113_3411	COG0463	Glycosyl transferase, family 2
Mic7113_3414	COG0515	serine threonine protein kinase
Mic7113_3416	COG0784	Response regulator, receiver
Mic7113_3416	COG2205	protein histidine kinase activity
Mic7113_3418	COG0482	sulfurtransferase activity
Mic7113_3419	COG2046	Belongs to the sulfate adenylyltransferase family
Mic7113_3423	COG2326	polyphosphate kinase activity
Mic7113_3428	COG1361	Conserved repeat domain
Mic7113_3430	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Mic7113_3436	COG0129	dihydroxy-acid dehydratase activity
Mic7113_3440	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Mic7113_3445	COG0779	Required for maturation of 30S ribosomal subunits
Mic7113_3446	COG0195	Participates in both transcription termination and antitermination
Mic7113_3448	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Mic7113_3448	COG3266	domain, Protein
Mic7113_3454	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Mic7113_3458	COG2385	sporulation resulting in formation of a cellular spore
Mic7113_3459	COG1234	tRNA 3'-trailer cleavage
Mic7113_3464	COG0501	Belongs to the peptidase M48B family
Mic7113_3471	COG0529	Catalyzes the synthesis of activated sulfate
Mic7113_3481	COG0270	DNA (cytosine-5-)-methyltransferase activity
Mic7113_3491	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Mic7113_3492	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Mic7113_3493	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Mic7113_3503	COG1649	PFAM Uncharacterised BCR, COG1649
Mic7113_3506	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Mic7113_3508	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Mic7113_3510	COG0745	RESPONSE REGULATOR receiver
Mic7113_3512	COG5002	protein histidine kinase activity
Mic7113_3515	COG0475	glutathione-regulated potassium exporter activity
Mic7113_3516	COG0659	secondary active sulfate transmembrane transporter activity
Mic7113_3521	COG0602	queuosine metabolic process
Mic7113_3522	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Mic7113_3526	COG0297	glycogen (starch) synthase activity
Mic7113_3528	COG0799	negative regulation of ribosome biogenesis
Mic7113_3532	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Mic7113_3534	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Mic7113_3542	COG1429	ligase activity, forming nitrogen-metal bonds
Mic7113_3544	COG0785	Cytochrome C biogenesis protein
Mic7113_3545	COG0753	catalase activity
Mic7113_3558	COG0746	molybdenum cofactor guanylyltransferase activity
Mic7113_3560	COG4251	negative regulation of phosphorylation
Mic7113_3560	COG3706	GGDEF domain
Mic7113_3560	COG2203	Gaf domain
Mic7113_3560	COG5001	Diguanylate cyclase
Mic7113_3562	COG5002	protein histidine kinase activity
Mic7113_3565	COG1252	NADH dehydrogenase
Mic7113_3569	COG1215	transferase activity, transferring glycosyl groups
Mic7113_3572	COG1192	Involved in chromosome partitioning
Mic7113_3573	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Mic7113_3574	COG2985	domain, Protein
Mic7113_3574	COG0569	domain protein
Mic7113_3575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Mic7113_3577	COG1104	cysteine desulfurase activity
Mic7113_3578	COG0534	Mate efflux family protein
Mic7113_3582	COG1752	Esterase of the alpha-beta hydrolase superfamily
Mic7113_3586	COG1166	arginine decarboxylase activity
Mic7113_3595	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Mic7113_3599	COG0768	penicillin binding
Mic7113_3600	COG0768	penicillin binding
Mic7113_3601	COG3842	ATPase activity
Mic7113_3603	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Mic7113_3604	COG1176	ABC-type spermidine putrescine transport system, permease component I
Mic7113_3605	COG1177	transmembrane transport
Mic7113_3606	COG2205	protein histidine kinase activity
Mic7113_3607	COG0438	transferase activity, transferring glycosyl groups
Mic7113_3612	COG3307	-O-antigen
Mic7113_3614	COG1408	metallophosphoesterase
Mic7113_3632	COG1012	belongs to the aldehyde dehydrogenase family
Mic7113_3633	COG0745	RESPONSE REGULATOR receiver
Mic7113_3636	COG1063	alcohol dehydrogenase
Mic7113_3638	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Mic7113_3639	COG0673	inositol 2-dehydrogenase activity
Mic7113_3642	COG0732	type I restriction modification DNA specificity domain
Mic7113_3645	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
Mic7113_3650	COG2003	Belongs to the UPF0758 family
Mic7113_3651	COG0572	uridine kinase
Mic7113_3653	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Mic7113_3654	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Mic7113_3655	COG0640	Transcriptional regulator
Mic7113_3660	COG1216	Glycosyl transferase, family 2
Mic7113_3662	COG0488	(ABC) transporter
Mic7113_3665	COG0667	Aldo Keto reductase
Mic7113_3668	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Mic7113_3669	COG0745	RESPONSE REGULATOR receiver
Mic7113_3675	COG1216	Glycosyl transferase, family 2
Mic7113_3677	COG3320	Male sterility
Mic7113_3677	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Mic7113_3678	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Mic7113_3679	COG1619	proteins homologs of microcin C7 resistance protein MccF
Mic7113_3680	COG0457	Tetratricopeptide repeat
Mic7113_3682	COG0438	transferase activity, transferring glycosyl groups
Mic7113_3683	COG0697	spore germination
Mic7113_3684	COG0616	signal peptide processing
Mic7113_3690	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Mic7113_3694	COG0416	fatty acid biosynthetic process
Mic7113_3695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Mic7113_3696	COG3850	Histidine kinase
Mic7113_3696	COG4999	Histidine kinase
Mic7113_3696	COG2205	protein histidine kinase activity
Mic7113_3696	COG3437	response regulator, receiver
Mic7113_3699	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Mic7113_3699	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Mic7113_3701	COG3266	domain, Protein
Mic7113_3701	COG2911	Protein conserved in bacteria
Mic7113_3701	COG1361	Conserved repeat domain
Mic7113_3702	COG2205	protein histidine kinase activity
Mic7113_3710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Mic7113_3711	COG0750	zinc metalloprotease
Mic7113_3713	COG4251	negative regulation of phosphorylation
Mic7113_3714	COG5002	protein histidine kinase activity
Mic7113_3715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Mic7113_3716	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Mic7113_3720	COG0473	3-isopropylmalate dehydrogenase activity
Mic7113_3722	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Mic7113_3724	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Mic7113_3726	COG2010	Cytochrome c
Mic7113_3727	COG2010	Cytochrome c
Mic7113_3732	COG0109	protoheme IX farnesyltransferase activity
Mic7113_3734	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Mic7113_3735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Mic7113_3736	COG1845	cytochrome c oxidase, subunit III
Mic7113_3737	COG0366	Alpha amylase catalytic
Mic7113_3738	COG0366	Alpha amylase catalytic
Mic7113_3739	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Mic7113_3745	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Mic7113_3747	COG0154	amidase activity
Mic7113_3750	COG1554	hydrolase, family 65, central catalytic
Mic7113_3751	COG0438	transferase activity, transferring glycosyl groups
Mic7113_3753	COG0024	Methionine aminopeptidase
Mic7113_3755	COG0612	Peptidase, M16
Mic7113_3764	COG1672	PFAM Archaeal ATPase
Mic7113_3764	COG2319	Wd-40 repeat
Mic7113_3765	COG0628	permease
Mic7113_3769	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Mic7113_3773	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Mic7113_3774	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Mic7113_3778	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Mic7113_3782	COG0066	3-isopropylmalate dehydratase activity
Mic7113_3783	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Mic7113_3784	COG2954	triphosphatase activity
Mic7113_3785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Mic7113_3786	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Mic7113_3787	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Mic7113_3788	COG1597	lipid kinase activity
Mic7113_3793	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Mic7113_3795	COG5002	protein histidine kinase activity
Mic7113_3800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Mic7113_3805	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Mic7113_3806	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Mic7113_3808	COG0163	prenyltransferase activity
Mic7113_3809	COG0557	exoribonuclease II activity
Mic7113_3811	COG0740	serine-type endopeptidase activity
Mic7113_3814	COG0393	Putative heavy-metal-binding
Mic7113_3827	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Mic7113_3828	COG1132	(ABC) transporter
Mic7113_3830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Mic7113_3833	COG0297	glycogen (starch) synthase activity
Mic7113_3835	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Mic7113_3836	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Mic7113_3844	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Mic7113_3845	COG0395	ABC-type sugar transport system, permease component
Mic7113_3848	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
Mic7113_3849	COG0649	NAD binding
Mic7113_3850	COG0275	rRNA processing
Mic7113_3853	COG0343	queuine tRNA-ribosyltransferase activity
Mic7113_3856	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Mic7113_3859	COG4581	dead DEAH box helicase
Mic7113_3860	COG2124	cytochrome p450
Mic7113_3861	COG1309	transcriptional regulator
Mic7113_3863	COG0360	Binds together with S18 to 16S ribosomal RNA
Mic7113_3864	COG0179	Fumarylacetoacetate (FAA) hydrolase
Mic7113_3867	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Mic7113_3869	COG1546	Belongs to the CinA family
Mic7113_3869	COG1058	Belongs to the CinA family
Mic7113_3871	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Mic7113_3875	COG1480	7TM receptor with intracellular HD hydrolase
Mic7113_3876	COG0039	L-malate dehydrogenase activity
Mic7113_3878	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Mic7113_3884	COG2304	oxidoreductase activity
Mic7113_3886	COG2310	stress, protein
Mic7113_3891	COG0372	Belongs to the citrate synthase family
Mic7113_3892	COG2062	phosphohistidine phosphatase, SixA
Mic7113_3896	COG3706	GGDEF domain
Mic7113_3896	COG4251	negative regulation of phosphorylation
Mic7113_3896	COG2203	Gaf domain
Mic7113_3896	COG5001	Diguanylate cyclase
Mic7113_3897	COG5002	protein histidine kinase activity
Mic7113_3897	COG2198	Histidine kinase
Mic7113_3897	COG0784	Response regulator, receiver
Mic7113_3898	COG0501	Belongs to the peptidase M48B family
Mic7113_3907	COG0863	Belongs to the N(4) N(6)-methyltransferase family
Mic7113_3908	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Mic7113_3917	COG2124	cytochrome p450
Mic7113_3920	COG0515	serine threonine protein kinase
Mic7113_3920	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_3923	COG0745	RESPONSE REGULATOR receiver
Mic7113_3928	COG0723	plastoquinol--plastocyanin reductase activity
Mic7113_3930	COG0784	Response regulator, receiver
Mic7113_3930	COG5002	protein histidine kinase activity
Mic7113_3931	COG1131	(ABC) transporter
Mic7113_3934	COG0751	glycine-tRNA ligase activity
Mic7113_3935	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Mic7113_3941	COG5001	Diguanylate cyclase
Mic7113_3941	COG4251	negative regulation of phosphorylation
Mic7113_3941	COG2203	Gaf domain
Mic7113_3941	COG3706	GGDEF domain
Mic7113_3947	COG0515	serine threonine protein kinase
Mic7113_3949	COG0575	Belongs to the CDS family
Mic7113_3951	COG1982	Orn Lys Arg decarboxylase major
Mic7113_3953	COG0012	GTP binding
Mic7113_3954	COG4953	penicillin-binding protein 1C
Mic7113_3962	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Mic7113_3964	COG0045	succinate-CoA ligase (ADP-forming) activity
Mic7113_3965	COG0300	oxidoreductase activity
Mic7113_3971	COG2066	Belongs to the glutaminase family
Mic7113_3974	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Mic7113_3980	COG0571	ribonuclease III activity
Mic7113_3984	COG2205	protein histidine kinase activity
Mic7113_3984	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Mic7113_3987	COG2172	sigma factor antagonist activity
Mic7113_3988	COG1366	Belongs to the anti-sigma-factor antagonist family
Mic7113_3989	COG1366	Belongs to the anti-sigma-factor antagonist family
Mic7113_3999	COG0494	nUDIX hydrolase
Mic7113_4000	COG0667	Aldo Keto reductase
Mic7113_4004	COG0643	Histidine kinase
Mic7113_4004	COG0784	Response regulator, receiver
Mic7113_4004	COG2198	Histidine kinase
Mic7113_4005	COG0840	transmembrane signaling receptor activity
Mic7113_4005	COG2203	Gaf domain
Mic7113_4015	COG1174	glycine betaine transport
Mic7113_4018	COG4636	protein conserved in cyanobacteria
Mic7113_4021	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Mic7113_4022	COG4783	chaperone-mediated protein folding
Mic7113_4030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Mic7113_4031	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Mic7113_4035	COG2199	diguanylate cyclase activity
Mic7113_4035	COG2203	Gaf domain
Mic7113_4043	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Mic7113_4046	COG0515	serine threonine protein kinase
Mic7113_4046	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_4048	COG0515	serine threonine protein kinase
Mic7113_4048	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_4051	COG1566	PFAM secretion protein HlyD family protein
Mic7113_4053	COG2267	carboxylic ester hydrolase activity
Mic7113_4057	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Mic7113_4059	COG2852	Protein conserved in bacteria
Mic7113_4062	COG2081	HI0933 family
Mic7113_4063	COG1773	rubredoxin
Mic7113_4064	COG4572	Cation transport regulator
Mic7113_4070	COG4106	trans-aconitate 2-methyltransferase activity
Mic7113_4071	COG0583	DNA-binding transcription factor activity
Mic7113_4073	COG2205	protein histidine kinase activity
Mic7113_4073	COG0784	Response regulator, receiver
Mic7113_4081	COG0516	GMP reductase activity
Mic7113_4081	COG0517	IMP dehydrogenase activity
Mic7113_4085	COG1573	uracil-dna glycosylase
Mic7113_4088	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Mic7113_4089	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Mic7113_4092	COG4191	Histidine kinase
Mic7113_4092	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Mic7113_4094	COG0515	serine threonine protein kinase
Mic7113_4095	COG3266	domain, Protein
Mic7113_4095	COG0515	serine threonine protein kinase
Mic7113_4100	COG0745	RESPONSE REGULATOR receiver
Mic7113_4104	COG3773	Cell wall hydrolase
Mic7113_4104	COG3409	Peptidoglycan-binding domain 1 protein
Mic7113_4105	COG0673	inositol 2-dehydrogenase activity
Mic7113_4106	COG1201	RNA secondary structure unwinding
Mic7113_4107	COG0312	modulator of DNA gyrase
Mic7113_4108	COG0312	modulator of DNA gyrase
Mic7113_4111	COG1619	proteins homologs of microcin C7 resistance protein MccF
Mic7113_4112	COG1461	Dihydroxyacetone kinase
Mic7113_4115	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Mic7113_4119	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Mic7113_4123	COG2048	Heterodisulfide reductase, subunit B
Mic7113_4124	COG4221	oxidoreductase activity
Mic7113_4125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Mic7113_4128	COG2244	polysaccharide biosynthetic process
Mic7113_4130	COG1216	Glycosyl transferase, family 2
Mic7113_4130	COG0463	Glycosyl transferase, family 2
Mic7113_4131	COG1216	Glycosyl transferase, family 2
Mic7113_4131	COG0463	Glycosyl transferase, family 2
Mic7113_4132	COG0438	transferase activity, transferring glycosyl groups
Mic7113_4133	COG0463	Glycosyl transferase, family 2
Mic7113_4133	COG1216	Glycosyl transferase, family 2
Mic7113_4135	COG4447	cellulose binding
Mic7113_4137	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Mic7113_4141	COG0826	peptidase U32
Mic7113_4142	COG0628	permease
Mic7113_4146	COG0784	Response regulator, receiver
Mic7113_4146	COG5002	protein histidine kinase activity
Mic7113_4148	COG4251	negative regulation of phosphorylation
Mic7113_4149	COG4251	negative regulation of phosphorylation
Mic7113_4150	COG2197	response regulator
Mic7113_4151	COG2204	response regulator
Mic7113_4154	COG0659	secondary active sulfate transmembrane transporter activity
Mic7113_4158	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Mic7113_4162	COG0745	RESPONSE REGULATOR receiver
Mic7113_4164	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Mic7113_4170	COG0424	maF-like protein
Mic7113_4174	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Mic7113_4178	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_4178	COG0515	serine threonine protein kinase
Mic7113_4181	COG0497	DNA recombination
Mic7113_4182	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Mic7113_4185	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_4185	COG0515	serine threonine protein kinase
Mic7113_4187	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_4187	COG0515	serine threonine protein kinase
Mic7113_4188	COG0484	heat shock protein binding
Mic7113_4190	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Mic7113_4191	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Mic7113_4192	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Mic7113_4193	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Mic7113_4195	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
Mic7113_4196	COG4451	ribulose bisphosphate carboxylase, small
Mic7113_4196	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Mic7113_4197	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Mic7113_4198	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Mic7113_4200	COG0583	DNA-binding transcription factor activity
Mic7113_4201	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Mic7113_4211	COG2045	Belongs to the ComB family
Mic7113_4212	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Mic7113_4213	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Mic7113_4214	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Mic7113_4214	COG2199	diguanylate cyclase activity
Mic7113_4215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Mic7113_4217	COG0488	(ABC) transporter
Mic7113_4218	COG4106	trans-aconitate 2-methyltransferase activity
Mic7113_4219	COG0384	phenazine biosynthesis protein PhzF
Mic7113_4220	COG0671	phosphoesterase, PA-phosphatase related
Mic7113_4222	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Mic7113_4222	COG0426	domain, Protein
Mic7113_4226	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Mic7113_4226	COG0426	domain, Protein
Mic7113_4228	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Mic7113_4229	COG0508	dehydrogenase complex catalyzes the overall conversion of
Mic7113_4229	COG0596	Alpha beta hydrolase
Mic7113_4232	COG0165	Argininosuccinate lyase
Mic7113_4234	COG2208	phosphoserine phosphatase activity
Mic7113_4235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Mic7113_4237	COG5002	protein histidine kinase activity
Mic7113_4237	COG2198	Histidine kinase
Mic7113_4237	COG0784	Response regulator, receiver
Mic7113_4238	COG0784	Response regulator, receiver
Mic7113_4238	COG4191	Histidine kinase
Mic7113_4239	COG1070	Carbohydrate kinase
Mic7113_4244	COG3621	Patatin-like phospholipase
Mic7113_4247	COG1028	Short-chain dehydrogenase reductase Sdr
Mic7113_4250	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Mic7113_4250	COG0758	DNA mediated transformation
Mic7113_4257	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Mic7113_4258	COG0745	RESPONSE REGULATOR receiver
Mic7113_4261	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Mic7113_4262	COG0581	inorganic phosphate transmembrane transporter activity
Mic7113_4263	COG0573	inorganic phosphate transmembrane transporter activity
Mic7113_4264	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Mic7113_4268	COG0848	biopolymer transport protein
Mic7113_4269	COG0811	peptide transport
Mic7113_4271	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Mic7113_4272	COG3781	membrane
Mic7113_4273	COG3781	membrane
Mic7113_4275	COG1028	Short-chain dehydrogenase reductase Sdr
Mic7113_4278	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Mic7113_4283	COG1490	D-aminoacyl-tRNA deacylase activity
Mic7113_4284	COG5001	Diguanylate cyclase
Mic7113_4284	COG4251	negative regulation of phosphorylation
Mic7113_4284	COG3706	GGDEF domain
Mic7113_4284	COG2203	Gaf domain
Mic7113_4285	COG0523	cobalamin synthesis protein
Mic7113_4286	COG0215	cysteine-tRNA ligase activity
Mic7113_4295	COG1324	tolerance protein
Mic7113_4299	COG0629	single-stranded DNA binding
Mic7113_4300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Mic7113_4302	COG2099	Precorrin-6x reductase
Mic7113_4305	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Mic7113_4306	COG0740	serine-type endopeptidase activity
Mic7113_4307	COG0544	peptidyl-prolyl cis-trans isomerase activity
Mic7113_4308	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Mic7113_4309	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Mic7113_4310	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Mic7113_4314	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Mic7113_4319	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Mic7113_4320	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Mic7113_4321	COG4208	sulfate ABC transporter
Mic7113_4322	COG0784	Response regulator, receiver
Mic7113_4322	COG5002	protein histidine kinase activity
Mic7113_4325	COG0784	Response regulator, receiver
Mic7113_4328	COG2201	protein-glutamate methylesterase activity
Mic7113_4329	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Mic7113_4331	COG0436	Aminotransferase
Mic7113_4334	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Mic7113_4336	COG1845	cytochrome c oxidase, subunit III
Mic7113_4337	COG2815	serine threonine protein kinase
Mic7113_4337	COG0515	serine threonine protein kinase
Mic7113_4346	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Mic7113_4347	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Mic7113_4349	COG1595	DNA-templated transcription, initiation
Mic7113_4350	COG0784	Response regulator, receiver
Mic7113_4351	COG1376	ErfK ybiS ycfS ynhG family protein
Mic7113_4353	COG0739	heme binding
Mic7113_4356	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Mic7113_4358	COG0412	Dienelactone hydrolase
Mic7113_4362	COG1215	transferase activity, transferring glycosyl groups
Mic7113_4363	COG0463	Glycosyl transferase, family 2
Mic7113_4366	COG0840	transmembrane signaling receptor activity
Mic7113_4366	COG2203	Gaf domain
Mic7113_4367	COG2202	Pas domain
Mic7113_4367	COG1366	Belongs to the anti-sigma-factor antagonist family
Mic7113_4368	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Mic7113_4369	COG0589	response to stress
Mic7113_4370	COG0126	phosphoglycerate kinase activity
Mic7113_4382	COG0719	Fe-S assembly protein
Mic7113_4383	COG0396	ATPase activity
Mic7113_4384	COG0719	Fe-S assembly protein
Mic7113_4385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Mic7113_4401	COG1702	phosphate starvation-inducible protein PhoH
Mic7113_4402	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Mic7113_4403	COG0228	four-way junction DNA binding
Mic7113_4404	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Mic7113_4406	COG0784	Response regulator, receiver
Mic7113_4406	COG0835	chemotaxis
Mic7113_4410	COG2226	methyltransferase
Mic7113_4410	COG1073	alpha beta
Mic7113_4412	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Mic7113_4412	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Mic7113_4414	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Mic7113_4415	COG4095	Psort location CytoplasmicMembrane, score
Mic7113_4420	COG1472	Belongs to the glycosyl hydrolase 3 family
Mic7113_4421	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Mic7113_4422	COG0009	L-threonylcarbamoyladenylate synthase
Mic7113_4424	COG0587	DNA-directed DNA polymerase activity
Mic7113_4428	COG0463	Glycosyl transferase, family 2
Mic7113_4432	COG0515	serine threonine protein kinase
Mic7113_4432	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_4438	COG2205	protein histidine kinase activity
Mic7113_4445	COG0463	Glycosyl transferase, family 2
Mic7113_4450	COG1361	Conserved repeat domain
Mic7113_4451	COG1596	polysaccharide export
Mic7113_4452	COG0489	protein tyrosine kinase activity
Mic7113_4453	COG0023	Translation Initiation Factor
Mic7113_4455	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Mic7113_4457	COG2205	protein histidine kinase activity
Mic7113_4457	COG3437	response regulator, receiver
Mic7113_4457	COG3850	Histidine kinase
Mic7113_4457	COG4999	Histidine kinase
Mic7113_4459	COG0481	GTPase activity
Mic7113_4460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Mic7113_4461	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Mic7113_4462	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Mic7113_4463	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Mic7113_4465	COG3852	Histidine kinase
Mic7113_4470	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Mic7113_4478	COG1598	PFAM Uncharacterised protein family UPF0150
Mic7113_4482	COG0459	protein refolding
Mic7113_4483	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Mic7113_4484	COG3411	Ferredoxin
Mic7113_4485	COG0745	RESPONSE REGULATOR receiver
Mic7113_4488	COG1085	galactose-1-phosphate uridylyltransferase
Mic7113_4491	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Mic7113_4495	COG0371	Dehydrogenase
Mic7113_4496	COG0436	Aminotransferase
Mic7113_4498	COG3788	relative of glutathione S-transferase, MAPEG superfamily
Mic7113_4500	COG0784	Response regulator, receiver
Mic7113_4501	COG4251	negative regulation of phosphorylation
Mic7113_4502	COG0784	Response regulator, receiver
Mic7113_4503	COG0697	spore germination
Mic7113_4508	COG2770	Histidine kinase
Mic7113_4508	COG2208	phosphoserine phosphatase activity
Mic7113_4511	COG0667	Aldo Keto reductase
Mic7113_4513	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Mic7113_4516	COG4555	ABC transporter
Mic7113_4517	COG0724	RNA recognition motif
Mic7113_4518	COG0024	Methionine aminopeptidase
Mic7113_4519	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Mic7113_4520	COG0022	dehydrogenase e1 component
Mic7113_4520	COG0508	dehydrogenase complex catalyzes the overall conversion of
Mic7113_4521	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Mic7113_4522	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Mic7113_4525	COG1295	ribonuclease BN
Mic7113_4529	COG0058	SHG alpha-glucan phosphorylase activity
Mic7113_4534	COG0395	ABC-type sugar transport system, permease component
Mic7113_4535	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
Mic7113_4537	COG5322	oxidoreductase activity
Mic7113_4538	COG0825	malonyl-CoA metabolic process
Mic7113_4539	COG1028	Short-chain dehydrogenase reductase Sdr
Mic7113_4540	COG0302	gtp cyclohydrolase
Mic7113_4541	COG5002	protein histidine kinase activity
Mic7113_4547	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Mic7113_4548	COG1570	exodeoxyribonuclease VII activity
Mic7113_4551	COG4991	sh3 domain protein
Mic7113_4551	COG0515	serine threonine protein kinase
Mic7113_4551	COG3064	Membrane
Mic7113_4556	COG1722	exodeoxyribonuclease VII activity
Mic7113_4564	COG0589	response to stress
Mic7113_4564	COG0475	glutathione-regulated potassium exporter activity
Mic7113_4578	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Mic7113_4579	COG0513	Belongs to the DEAD box helicase family
Mic7113_4580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Mic7113_4581	COG0434	BtpA family
Mic7113_4582	COG4243	Vitamin k epoxide reductase
Mic7113_4587	COG0405	Gamma-glutamyltransferase
Mic7113_4589	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Mic7113_4591	COG0450	alkyl hydroperoxide reductase
Mic7113_4596	COG3447	MASE1 domain protein
Mic7113_4596	COG5002	protein histidine kinase activity
Mic7113_4596	COG5001	Diguanylate cyclase
Mic7113_4597	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Mic7113_4601	COG0346	lactoylglutathione lyase activity
Mic7113_4606	COG0563	adenylate kinase activity
Mic7113_4607	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Mic7113_4609	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Mic7113_4612	COG1836	PFAM Integral membrane protein DUF92
Mic7113_4616	COG0724	RNA recognition motif
Mic7113_4617	COG1803	Methylglyoxal synthase
Mic7113_4617	COG1597	lipid kinase activity
Mic7113_4620	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Mic7113_4620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Mic7113_4623	COG1492	cobalamin metabolic process
Mic7113_4625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Mic7113_4630	COG2131	deaminase
Mic7113_4638	COG0668	transmembrane transport
Mic7113_4641	COG0668	transmembrane transport
Mic7113_4642	COG0668	transmembrane transport
Mic7113_4651	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Mic7113_4653	COG0628	permease
Mic7113_4661	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Mic7113_4663	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Mic7113_4664	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Mic7113_4665	COG0776	regulation of translation
Mic7113_4666	COG1450	Type ii and iii secretion system protein
Mic7113_4673	COG3266	domain, Protein
Mic7113_4673	COG1361	Conserved repeat domain
Mic7113_4673	COG2911	Protein conserved in bacteria
Mic7113_4674	COG1361	Conserved repeat domain
Mic7113_4678	COG1316	TRANSCRIPTIONal
Mic7113_4680	COG0010	Belongs to the arginase family
Mic7113_4682	COG0528	UMP kinase activity
Mic7113_4683	COG0233	cytoplasmic translational termination
Mic7113_4687	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Mic7113_4688	COG0546	phosphoglycolate phosphatase activity
Mic7113_4690	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Mic7113_4696	COG2161	toxin-antitoxin pair type II binding
Mic7113_4701	COG0714	Associated with various cellular activities
Mic7113_4702	COG0196	riboflavin kinase activity
Mic7113_4703	COG1234	tRNA 3'-trailer cleavage
Mic7113_4705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Mic7113_4706	COG0189	ligase activity
Mic7113_4711	COG0339	signal peptide processing
Mic7113_4715	COG0285	dihydrofolate synthase activity
Mic7113_4717	COG1397	ADP-ribosylglycohydrolase
Mic7113_4730	COG1049	propionate catabolic process, 2-methylcitrate cycle
Mic7113_4732	COG2010	Cytochrome c
Mic7113_4734	COG0742	ribosomal rna small subunit methyltransferase
Mic7113_4735	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Mic7113_4736	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Mic7113_4754	COG0237	dephospho-CoA kinase activity
Mic7113_4760	COG0436	Aminotransferase
Mic7113_4764	COG1696	Membrane protein involved in D-alanine export
Mic7113_4767	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Mic7113_4768	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Mic7113_4768	COG0574	Belongs to the PEP-utilizing enzyme family
Mic7113_4769	COG4191	Histidine kinase
Mic7113_4771	COG2205	protein histidine kinase activity
Mic7113_4771	COG0784	Response regulator, receiver
Mic7113_4775	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Mic7113_4776	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Mic7113_4777	COG4208	sulfate ABC transporter
Mic7113_4781	COG3848	Pyruvate phosphate dikinase
Mic7113_4781	COG0574	Belongs to the PEP-utilizing enzyme family
Mic7113_4784	COG1361	Conserved repeat domain
Mic7113_4784	COG3266	domain, Protein
Mic7113_4784	COG2911	Protein conserved in bacteria
Mic7113_4788	COG1175	transmembrane transport
Mic7113_4792	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Mic7113_4792	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Mic7113_4796	COG0024	Methionine aminopeptidase
Mic7113_4800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Mic7113_4800	COG0140	phosphoribosyl-ATP diphosphatase activity
Mic7113_4804	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Mic7113_4806	COG1666	GTP binding
Mic7113_4814	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Mic7113_4816	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Mic7113_4828	COG1278	Cold shock
Mic7113_4830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Mic7113_4831	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Mic7113_4832	COG1116	anion transmembrane transporter activity
Mic7113_4832	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Mic7113_4833	COG1116	anion transmembrane transporter activity
Mic7113_4835	COG4251	negative regulation of phosphorylation
Mic7113_4836	COG5002	protein histidine kinase activity
Mic7113_4836	COG5001	Diguanylate cyclase
Mic7113_4836	COG3447	MASE1 domain protein
Mic7113_4838	COG5002	protein histidine kinase activity
Mic7113_4840	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Mic7113_4840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Mic7113_4843	COG2988	succinylglutamate desuccinylase activity
Mic7113_4846	COG0405	Gamma-glutamyltransferase
Mic7113_4848	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Mic7113_4852	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Mic7113_4860	COG1716	ATPase activity
Mic7113_4861	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
Mic7113_4865	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Mic7113_4871	COG0538	isocitrate dehydrogenase activity
Mic7113_4872	COG0745	RESPONSE REGULATOR receiver
Mic7113_4873	COG0515	serine threonine protein kinase
Mic7113_4874	COG2202	Pas domain
Mic7113_4874	COG2205	protein histidine kinase activity
Mic7113_4876	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Mic7113_4878	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_4878	COG0515	serine threonine protein kinase
Mic7113_4880	COG0429	hydrolase of the alpha beta-hydrolase fold
Mic7113_4881	COG0745	RESPONSE REGULATOR receiver
Mic7113_4883	COG0644	oxidoreductase
Mic7113_4884	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Mic7113_4885	COG0747	negative chemotaxis
Mic7113_4886	COG2385	sporulation resulting in formation of a cellular spore
Mic7113_4889	COG0181	hydroxymethylbilane synthase activity
Mic7113_4890	COG5398	heme oxygenase
Mic7113_4891	COG2197	response regulator
Mic7113_4892	COG0297	glycogen (starch) synthase activity
Mic7113_4893	COG0784	Response regulator, receiver
Mic7113_4893	COG2205	protein histidine kinase activity
Mic7113_4904	COG0460	homoserine dehydrogenase
Mic7113_4909	COG0438	transferase activity, transferring glycosyl groups
Mic7113_4921	COG1192	Involved in chromosome partitioning
Mic7113_4934	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Mic7113_4936	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Mic7113_4936	COG0426	domain, Protein
Mic7113_4942	COG0426	domain, Protein
Mic7113_4942	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Mic7113_4945	COG4251	negative regulation of phosphorylation
Mic7113_4947	COG1132	(ABC) transporter
Mic7113_4949	COG2264	protein methyltransferase activity
Mic7113_4950	COG3239	Fatty acid desaturase
Mic7113_4957	COG0586	Pfam SNARE associated Golgi protein
Mic7113_4958	COG3932	Exopolysaccharide synthesis, ExoD
Mic7113_4960	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Mic7113_4963	COG0668	transmembrane transport
Mic7113_4971	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Mic7113_4973	COG3781	membrane
Mic7113_4975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Mic7113_4978	COG0288	reversible hydration of carbon dioxide
Mic7113_4982	COG0419	ATPase involved in DNA repair
Mic7113_4991	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Mic7113_4993	COG3103	Sh3 type 3 domain protein
Mic7113_4993	COG0860	N-Acetylmuramoyl-L-alanine amidase
Mic7113_4993	COG4991	sh3 domain protein
Mic7113_4995	COG0463	Glycosyl transferase, family 2
Mic7113_4995	COG1216	Glycosyl transferase, family 2
Mic7113_4996	COG1216	Glycosyl transferase, family 2
Mic7113_4997	COG0463	Glycosyl transferase, family 2
Mic7113_4997	COG1216	Glycosyl transferase, family 2
Mic7113_4998	COG0463	Glycosyl transferase, family 2
Mic7113_4998	COG1216	Glycosyl transferase, family 2
Mic7113_5000	COG0542	response to heat
Mic7113_5001	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Mic7113_5004	COG0004	ammonium transporteR
Mic7113_5005	COG3266	domain, Protein
Mic7113_5005	COG2911	Protein conserved in bacteria
Mic7113_5005	COG1361	Conserved repeat domain
Mic7113_5006	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Mic7113_5007	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Mic7113_5010	COG1994	Peptidase M50
Mic7113_5011	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Mic7113_5018	COG2363	Small membrane protein
Mic7113_5027	COG0017	Asparaginyl-tRNA synthetase
Mic7113_5032	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Mic7113_5042	COG0492	ferredoxin-NADP+ reductase activity
Mic7113_5044	COG0463	Glycosyl transferase, family 2
Mic7113_5044	COG0457	Tetratricopeptide repeat
Mic7113_5045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Mic7113_5046	COG1940	carbohydrate kinase activity
Mic7113_5051	COG0504	CTP synthase activity
Mic7113_5052	COG0482	sulfurtransferase activity
Mic7113_5055	COG0326	Molecular chaperone. Has ATPase activity
Mic7113_5056	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Mic7113_5061	COG4968	Prepilin-type N-terminal cleavage methylation domain
Mic7113_5063	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Mic7113_5069	COG1331	Highly conserved protein containing a thioredoxin domain
Mic7113_5071	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Mic7113_5072	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Mic7113_5076	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
Mic7113_5079	COG0643	Histidine kinase
Mic7113_5079	COG2198	Histidine kinase
Mic7113_5083	COG0745	RESPONSE REGULATOR receiver
Mic7113_5086	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Mic7113_5087	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Mic7113_5088	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Mic7113_5089	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Mic7113_5090	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Mic7113_5098	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Mic7113_5099	COG0398	Pfam SNARE associated Golgi protein
Mic7113_5101	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
Mic7113_5103	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Mic7113_5105	COG2897	thiosulfate sulfurtransferase activity
Mic7113_5107	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Mic7113_5109	COG2226	methyltransferase
Mic7113_5112	COG0514	ATP-dependent DNA helicase (RecQ)
Mic7113_5114	COG0515	serine threonine protein kinase
Mic7113_5114	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_5116	COG0702	epimerase
Mic7113_5117	COG0071	Belongs to the small heat shock protein (HSP20) family
Mic7113_5120	COG1045	serine acetyltransferase
Mic7113_5121	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Mic7113_5122	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Mic7113_5127	COG5635	Nacht domain
Mic7113_5127	COG2319	Wd-40 repeat
Mic7113_5129	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
Mic7113_5130	COG0519	Catalyzes the synthesis of GMP from XMP
Mic7113_5130	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Mic7113_5132	COG0037	tRNA processing
Mic7113_5135	COG0408	coproporphyrinogen oxidase activity
Mic7113_5136	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Mic7113_5137	COG0583	DNA-binding transcription factor activity
Mic7113_5139	COG2264	protein methyltransferase activity
Mic7113_5140	COG0531	amino acid
Mic7113_5141	COG1653	transport
Mic7113_5146	COG3706	GGDEF domain
Mic7113_5146	COG2203	Gaf domain
Mic7113_5146	COG5001	Diguanylate cyclase
Mic7113_5146	COG4251	negative regulation of phosphorylation
Mic7113_5147	COG5002	protein histidine kinase activity
Mic7113_5152	COG2319	Wd-40 repeat
Mic7113_5153	COG0358	DNA primase activity
Mic7113_5155	COG0792	nuclease activity
Mic7113_5157	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Mic7113_5159	COG0569	domain protein
Mic7113_5160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Mic7113_5161	COG2226	methyltransferase
Mic7113_5163	COG1006	Multisubunit Na H antiporter MnhC subunit
Mic7113_5164	COG0651	ATP synthesis coupled electron transport
Mic7113_5173	COG0778	Nitroreductase
Mic7113_5175	COG0412	Dienelactone hydrolase
Mic7113_5176	COG0539	negative regulation of cytoplasmic translation
Mic7113_5179	COG0612	Peptidase, M16
Mic7113_5180	COG3001	Fructosamine kinase
Mic7113_5183	COG1420	regulation of RNA biosynthetic process
Mic7113_5184	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Mic7113_5184	COG0425	Belongs to the sulfur carrier protein TusA family
Mic7113_5188	COG0135	phosphoribosylanthranilate isomerase activity
Mic7113_5194	COG2361	Protein of unknown function DUF86
Mic7113_5195	COG2723	6-phospho-beta-galactosidase activity
Mic7113_5199	COG4178	(ABC) transporter
Mic7113_5202	COG0116	Belongs to the methyltransferase superfamily
Mic7113_5203	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Mic7113_5205	COG2267	carboxylic ester hydrolase activity
Mic7113_5209	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Mic7113_5210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Mic7113_5213	COG1797	cobyrinic acid a,c-diamide synthase activity
Mic7113_5214	COG3409	Peptidoglycan-binding domain 1 protein
Mic7113_5214	COG3429	Glucose-6-phosphate dehydrogenase subunit
Mic7113_5215	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Mic7113_5216	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Mic7113_5217	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Mic7113_5218	COG0205	6-phosphofructokinase activity
Mic7113_5219	COG0724	RNA recognition motif
Mic7113_5224	COG1045	serine acetyltransferase
Mic7113_5227	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Mic7113_5229	COG1376	ErfK ybiS ycfS ynhG family protein
Mic7113_5230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Mic7113_5231	COG0741	lytic transglycosylase activity
Mic7113_5232	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Mic7113_5234	COG1120	ATPase activity
Mic7113_5235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Mic7113_5236	COG0805	protein transport
Mic7113_5239	COG0723	plastoquinol--plastocyanin reductase activity
Mic7113_5240	COG3258	Cytochrome c
Mic7113_5245	COG0297	glycogen (starch) synthase activity
Mic7113_5247	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Mic7113_5248	COG0003	Pfam Anion-transporting ATPase
Mic7113_5251	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Mic7113_5253	COG0438	transferase activity, transferring glycosyl groups
Mic7113_5255	COG0367	asparagine synthase
Mic7113_5262	COG0728	peptidoglycan biosynthetic process
Mic7113_5264	COG1086	Polysaccharide biosynthesis protein
Mic7113_5276	COG0438	transferase activity, transferring glycosyl groups
Mic7113_5278	COG0745	RESPONSE REGULATOR receiver
Mic7113_5279	COG1160	GTP binding
Mic7113_5280	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Mic7113_5289	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Mic7113_5292	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Mic7113_5293	COG1799	cell septum assembly
Mic7113_5294	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Mic7113_5295	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Mic7113_5298	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Mic7113_5299	COG0840	transmembrane signaling receptor activity
Mic7113_5302	COG0784	Response regulator, receiver
Mic7113_5304	COG0037	tRNA processing
Mic7113_5306	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Mic7113_5310	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Mic7113_5312	COG0398	Pfam SNARE associated Golgi protein
Mic7113_5313	COG0463	Glycosyl transferase, family 2
Mic7113_5321	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
Mic7113_5323	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Mic7113_5333	COG0484	heat shock protein binding
Mic7113_5335	COG0740	serine-type endopeptidase activity
Mic7113_5336	COG0740	serine-type endopeptidase activity
Mic7113_5337	COG2304	oxidoreductase activity
Mic7113_5338	COG0784	Response regulator, receiver
Mic7113_5341	COG2203	Gaf domain
Mic7113_5341	COG0840	transmembrane signaling receptor activity
Mic7113_5342	COG2198	Histidine kinase
Mic7113_5342	COG0784	Response regulator, receiver
Mic7113_5342	COG0643	Histidine kinase
Mic7113_5343	COG4956	integral membrane protein (PIN domain superfamily)
Mic7113_5344	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Mic7113_5346	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Mic7113_5348	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Mic7113_5350	COG0443	Heat shock 70 kDa protein
Mic7113_5351	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Mic7113_5352	COG0724	RNA recognition motif
Mic7113_5353	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Mic7113_5354	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Mic7113_5357	COG0563	adenylate kinase activity
Mic7113_5358	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Mic7113_5359	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Mic7113_5360	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Mic7113_5361	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Mic7113_5362	COG3842	ATPase activity
Mic7113_5363	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Mic7113_5370	COG1484	DNA-dependent DNA replication
Mic7113_5373	COG3850	Histidine kinase
Mic7113_5373	COG4999	Histidine kinase
Mic7113_5373	COG2205	protein histidine kinase activity
Mic7113_5373	COG3437	response regulator, receiver
Mic7113_5374	COG0571	ribonuclease III activity
Mic7113_5378	COG0598	Magnesium transport protein CorA
Mic7113_5380	COG0459	protein refolding
Mic7113_5381	COG0640	Transcriptional regulator
Mic7113_5382	COG3118	belongs to the thioredoxin family
Mic7113_5384	COG0625	glutathione transferase activity
Mic7113_5385	COG1902	pentaerythritol trinitrate reductase activity
Mic7113_5386	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Mic7113_5388	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Mic7113_5389	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Mic7113_5393	COG0328	RNA-DNA hybrid ribonuclease activity
Mic7113_5394	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Mic7113_5395	COG1215	transferase activity, transferring glycosyl groups
Mic7113_5396	COG0300	oxidoreductase activity
Mic7113_5396	COG3000	fatty acid hydroxylase
Mic7113_5397	COG1217	gtp-binding protein TYPA
Mic7113_5399	COG0408	coproporphyrinogen oxidase activity
Mic7113_5403	COG3118	belongs to the thioredoxin family
Mic7113_5404	COG1028	Short-chain dehydrogenase reductase Sdr
Mic7113_5412	COG0415	Belongs to the DNA photolyase family
Mic7113_5413	COG0747	negative chemotaxis
Mic7113_5414	COG1216	Glycosyl transferase, family 2
Mic7113_5414	COG0463	Glycosyl transferase, family 2
Mic7113_5415	COG0601	transmembrane transport
Mic7113_5416	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Mic7113_5418	COG0577	efflux transmembrane transporter activity
Mic7113_5418	COG1136	(ABC) transporter
Mic7113_5422	COG0251	oxidation-reduction process
Mic7113_5424	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Mic7113_5430	COG0438	transferase activity, transferring glycosyl groups
Mic7113_5432	COG1178	ABC-type Fe3 transport system permease component
Mic7113_5434	COG1840	ABC-type Fe3 transport system, periplasmic component
Mic7113_5435	COG1840	ABC-type Fe3 transport system, periplasmic component
Mic7113_5436	COG0251	oxidation-reduction process
Mic7113_5438	COG1640	4-alpha-glucanotransferase
Mic7113_5440	COG1187	pseudouridine synthase activity
Mic7113_5447	COG0277	FAD linked oxidase domain protein
Mic7113_5448	COG0247	lactate metabolic process
Mic7113_5452	COG2217	Heavy metal translocating P-type atpase
Mic7113_5454	COG1716	ATPase activity
Mic7113_5454	COG5001	Diguanylate cyclase
Mic7113_5456	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Mic7113_5457	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Mic7113_5458	COG0529	Catalyzes the synthesis of activated sulfate
Mic7113_5461	COG0110	maltose O-acetyltransferase activity
Mic7113_5469	COG1126	abc transporter atp-binding protein
Mic7113_5470	COG0765	amino acid transport
Mic7113_5471	COG3237	CsbD-like
Mic7113_5473	COG2205	protein histidine kinase activity
Mic7113_5478	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Mic7113_5480	COG0720	synthase
Mic7113_5481	COG0484	heat shock protein binding
Mic7113_5482	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Mic7113_5483	COG1959	2 iron, 2 sulfur cluster binding
Mic7113_5484	COG3659	wide pore channel activity
Mic7113_5485	COG3659	wide pore channel activity
Mic7113_5486	COG2154	pterin-4-alpha-carbinolamine dehydratase
Mic7113_5489	COG1122	ATPase activity
Mic7113_5490	COG3688	RNA-binding protein containing a PIN domain
Mic7113_5494	COG0762	integral membrane protein
Mic7113_5496	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Mic7113_5506	COG3850	Histidine kinase
Mic7113_5506	COG5002	protein histidine kinase activity
Mic7113_5507	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Mic7113_5508	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Mic7113_5512	COG0540	Belongs to the ATCase OTCase family
Mic7113_5513	COG2239	Acts as a magnesium transporter
Mic7113_5516	COG2094	Belongs to the DNA glycosylase MPG family
Mic7113_5518	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Mic7113_5524	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Mic7113_5526	COG3631	Ketosteroid isomerase-related protein
Mic7113_5531	COG1136	(ABC) transporter
Mic7113_5532	COG1136	(ABC) transporter
Mic7113_5532	COG0577	efflux transmembrane transporter activity
Mic7113_5533	COG1566	PFAM secretion protein HlyD family protein
Mic7113_5537	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Mic7113_5542	COG4636	protein conserved in cyanobacteria
Mic7113_5544	COG0515	serine threonine protein kinase
Mic7113_5545	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Mic7113_5548	COG0142	geranyltranstransferase activity
Mic7113_5550	COG1819	glycosyl
Mic7113_5553	COG0406	alpha-ribazole phosphatase activity
Mic7113_5556	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Mic7113_5557	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Mic7113_5558	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Mic7113_5559	COG0085	RNA polymerase activity
Mic7113_5560	COG0084	hydrolase, TatD family'
Mic7113_5561	COG0268	Binds directly to 16S ribosomal RNA
Mic7113_5562	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Mic7113_5563	COG0589	response to stress
Mic7113_5567	COG2274	protein secretion by the type I secretion system
Mic7113_5568	COG1404	Belongs to the peptidase S8 family
Mic7113_5570	COG0702	epimerase
Mic7113_5573	COG0666	response to abiotic stimulus
Mic7113_5577	COG3751	2OG-Fe(II) oxygenase superfamily
Mic7113_5579	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Mic7113_5585	COG1252	NADH dehydrogenase
Mic7113_5589	COG0494	nUDIX hydrolase
Mic7113_5592	COG2119	membrane
Mic7113_5594	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Mic7113_5598	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Mic7113_5600	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Mic7113_5601	COG0052	Belongs to the universal ribosomal protein uS2 family
Mic7113_5602	COG3852	Histidine kinase
Mic7113_5603	COG1216	Glycosyl transferase, family 2
Mic7113_5608	COG1842	Phage shock protein A
Mic7113_5609	COG1842	Phage shock protein A
Mic7113_5610	COG3118	belongs to the thioredoxin family
Mic7113_5611	COG0436	Aminotransferase
Mic7113_5613	COG1164	Oligoendopeptidase f
Mic7113_5614	COG0322	excinuclease ABC activity
Mic7113_5615	COG1943	Transposase
Mic7113_5620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Mic7113_5623	COG0297	glycogen (starch) synthase activity
Mic7113_5624	COG0572	uridine kinase
Mic7113_5629	COG0667	Aldo Keto reductase
Mic7113_5633	COG0322	excinuclease ABC activity
Mic7113_5636	COG1649	PFAM Uncharacterised BCR, COG1649
Mic7113_5638	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Mic7113_5640	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Mic7113_5648	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Mic7113_5653	COG0724	RNA recognition motif
Mic7113_5654	COG3119	arylsulfatase activity
Mic7113_5655	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Mic7113_5659	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Mic7113_5661	COG0702	epimerase
Mic7113_5662	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Mic7113_5664	COG0784	Response regulator, receiver
Mic7113_5664	COG2205	protein histidine kinase activity
Mic7113_5672	COG3781	membrane
Mic7113_5676	COG0668	transmembrane transport
Mic7113_5677	COG2319	Wd-40 repeat
Mic7113_5677	COG1672	PFAM Archaeal ATPase
Mic7113_5679	COG0534	Mate efflux family protein
Mic7113_5682	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
Mic7113_5685	COG0784	Response regulator, receiver
Mic7113_5686	COG3447	MASE1 domain protein
Mic7113_5686	COG5001	Diguanylate cyclase
Mic7113_5686	COG5002	protein histidine kinase activity
Mic7113_5687	COG0745	RESPONSE REGULATOR receiver
Mic7113_5693	COG0134	indole-3-glycerol-phosphate synthase activity
Mic7113_5694	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Mic7113_5696	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Mic7113_5702	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Mic7113_5703	COG1090	epimerase
Mic7113_5709	COG2205	protein histidine kinase activity
Mic7113_5710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Mic7113_5711	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Mic7113_5715	COG5001	Diguanylate cyclase
Mic7113_5715	COG4251	negative regulation of phosphorylation
Mic7113_5715	COG3706	GGDEF domain
Mic7113_5715	COG2203	Gaf domain
Mic7113_5716	COG0745	RESPONSE REGULATOR receiver
Mic7113_5720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Mic7113_5722	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Mic7113_5723	COG1494	fructose-1,6-bisphosphatase
Mic7113_5724	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Mic7113_5725	COG1615	UPF0182 protein
Mic7113_5727	COG0463	Glycosyl transferase, family 2
Mic7113_5729	COG0438	transferase activity, transferring glycosyl groups
Mic7113_5730	COG0297	glycogen (starch) synthase activity
Mic7113_5733	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Mic7113_5741	COG2226	methyltransferase
Mic7113_5744	COG0297	glycogen (starch) synthase activity
Mic7113_5745	COG1215	transferase activity, transferring glycosyl groups
Mic7113_5749	COG2264	protein methyltransferase activity
Mic7113_5758	COG0489	protein tyrosine kinase activity
Mic7113_5759	COG0438	transferase activity, transferring glycosyl groups
Mic7113_5761	COG0438	transferase activity, transferring glycosyl groups
Mic7113_5762	COG0438	transferase activity, transferring glycosyl groups
Mic7113_5769	COG0189	ligase activity
Mic7113_5769	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Mic7113_5772	COG4242	Belongs to the peptidase S51 family
Mic7113_5774	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Mic7113_5779	COG1151	hydroxylamine reductase activity
Mic7113_5781	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Mic7113_5792	COG1733	regulation of RNA biosynthetic process
Mic7113_5800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Mic7113_5801	COG1803	Methylglyoxal synthase
Mic7113_5801	COG1597	lipid kinase activity
Mic7113_5802	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Mic7113_5805	COG4172	Belongs to the ABC transporter superfamily
Mic7113_5806	COG0848	biopolymer transport protein
Mic7113_5809	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Mic7113_5810	COG0601	transmembrane transport
Mic7113_5815	COG0515	serine threonine protein kinase
Mic7113_5815	COG3266	domain, Protein
Mic7113_5816	COG0515	serine threonine protein kinase
Mic7113_5817	COG0515	serine threonine protein kinase
Mic7113_5817	COG2815	serine threonine protein kinase
Mic7113_5818	COG0438	transferase activity, transferring glycosyl groups
Mic7113_5825	COG1028	Short-chain dehydrogenase reductase Sdr
Mic7113_5826	COG3631	Ketosteroid isomerase-related protein
Mic7113_5828	COG0693	protein deglycase activity
Mic7113_5834	COG4251	negative regulation of phosphorylation
Mic7113_5835	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Mic7113_5843	COG1842	Phage shock protein A
Mic7113_5844	COG0484	heat shock protein binding
Mic7113_5847	COG0542	response to heat
Mic7113_5848	COG0456	acetyltransferase
Mic7113_5849	COG0019	diaminopimelate decarboxylase activity
Mic7113_5850	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Mic7113_5851	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Mic7113_5856	COG0493	'glutamate synthase
Mic7113_5856	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Mic7113_5857	COG0617	tRNA 3'-terminal CCA addition
Mic7113_5859	COG0586	Pfam SNARE associated Golgi protein
Mic7113_5861	COG3706	GGDEF domain
Mic7113_5861	COG4251	negative regulation of phosphorylation
Mic7113_5861	COG5001	Diguanylate cyclase
Mic7113_5861	COG2203	Gaf domain
Mic7113_5862	COG1981	membrane
Mic7113_5864	COG2198	Histidine kinase
Mic7113_5864	COG0784	Response regulator, receiver
Mic7113_5864	COG0643	Histidine kinase
Mic7113_5865	COG2203	Gaf domain
Mic7113_5865	COG0840	transmembrane signaling receptor activity
Mic7113_5871	COG0709	Synthesizes selenophosphate from selenide and ATP
Mic7113_5873	COG0601	transmembrane transport
Mic7113_5877	COG3266	domain, Protein
Mic7113_5877	COG0515	serine threonine protein kinase
Mic7113_5881	COG0438	transferase activity, transferring glycosyl groups
Mic7113_5883	COG0071	Belongs to the small heat shock protein (HSP20) family
Mic7113_5890	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Mic7113_5904	COG0418	dihydroorotase activity
Mic7113_5908	COG2197	response regulator
Mic7113_5911	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Mic7113_5916	COG0438	transferase activity, transferring glycosyl groups
Mic7113_5920	COG5002	protein histidine kinase activity
Mic7113_5921	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Mic7113_5922	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Mic7113_5924	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Mic7113_5925	COG2204	response regulator
Mic7113_5927	COG5002	protein histidine kinase activity
Mic7113_5929	COG2205	protein histidine kinase activity
Mic7113_5931	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Mic7113_5933	COG0515	serine threonine protein kinase
Mic7113_5938	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Mic7113_5939	COG0594	ribonuclease P activity
Mic7113_5941	COG0706	membrane insertase activity
Mic7113_5945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Mic7113_5947	COG0463	Glycosyl transferase, family 2
Mic7113_5949	COG1657	PFAM Prenyltransferase squalene oxidase
Mic7113_5954	COG2831	hemolysin activation secretion protein
Mic7113_5965	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Mic7113_5980	COG0137	argininosuccinate synthase activity
Mic7113_5984	COG2197	response regulator
Mic7113_5985	COG4191	Histidine kinase
Mic7113_6008	COG2321	neutral zinc metallopeptidase
Mic7113_6012	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Mic7113_6014	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Mic7113_6015	COG0564	pseudouridine synthase activity
Mic7113_6020	COG2319	Wd-40 repeat
Mic7113_6020	COG1672	PFAM Archaeal ATPase
Mic7113_6026	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Mic7113_6027	COG5001	Diguanylate cyclase
Mic7113_6027	COG1716	ATPase activity
Mic7113_6031	COG0793	Belongs to the peptidase S41A family
Mic7113_6032	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Mic7113_6034	COG0438	transferase activity, transferring glycosyl groups
Mic7113_6040	COG0739	heme binding
Mic7113_6043	COG0628	permease
Mic7113_6047	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Mic7113_6048	COG0402	S-adenosylhomocysteine deaminase activity
Mic7113_6050	COG2124	cytochrome p450
Mic7113_6052	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Mic7113_6053	COG1695	Transcriptional regulator
Mic7113_6054	COG0857	belongs to the CobB CobQ family
Mic7113_6058	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Mic7113_6059	COG1802	Transcriptional regulator
Mic7113_6064	COG0222	ribosome binding
Mic7113_6075	COG1131	(ABC) transporter
Mic7113_6078	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Mic7113_6081	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Mic7113_6086	COG0723	plastoquinol--plastocyanin reductase activity
Mic7113_6094	COG1192	Involved in chromosome partitioning
Mic7113_6095	COG0028	Belongs to the TPP enzyme family
Mic7113_6098	COG0628	permease
Mic7113_6103	COG5002	protein histidine kinase activity
Mic7113_6105	COG1027	Aspartate ammonia-lyase
Mic7113_6109	COG0596	Alpha beta hydrolase
Mic7113_6115	COG4572	Cation transport regulator
Mic7113_6117	COG0668	transmembrane transport
Mic7113_6127	COG3842	ATPase activity
Mic7113_6129	COG0783	Belongs to the Dps family
Mic7113_6130	COG0612	Peptidase, M16
Mic7113_6133	COG0612	Peptidase, M16
Mic7113_6137	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Mic7113_6140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Mic7113_6141	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Mic7113_6142	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Mic7113_6143	COG0802	atpase or kinase
Mic7113_6144	COG2319	Wd-40 repeat
Mic7113_6144	COG3903	Transcriptional regulator
Mic7113_6148	COG0515	serine threonine protein kinase
Mic7113_6148	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_6149	COG0189	ligase activity
Mic7113_6150	COG4067	protein conserved in archaea
Mic7113_6150	COG0189	ligase activity
Mic7113_6152	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
Mic7113_6157	COG0596	Alpha beta hydrolase
Mic7113_6163	COG2843	Capsule synthesis protein
Mic7113_6164	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Mic7113_6165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Mic7113_6166	COG0572	uridine kinase
Mic7113_6176	COG1404	Belongs to the peptidase S8 family
Mic7113_6177	COG2319	Wd-40 repeat
Mic7113_6177	COG4249	Peptidase C14 caspase catalytic subunit p20
Mic7113_6181	COG0445	tRNA wobble uridine modification
Mic7113_6186	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Mic7113_6187	COG0539	negative regulation of cytoplasmic translation
Mic7113_6189	COG1132	(ABC) transporter
Mic7113_6191	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Mic7113_6193	COG0359	binds to the 23S rRNA
Mic7113_6194	COG1372	Participates in initiation and elongation during chromosome replication
Mic7113_6194	COG0305	Participates in initiation and elongation during chromosome replication
Mic7113_6194	COG1372	Participates in initiation and elongation during chromosome replication
Mic7113_6194	COG0305	Participates in initiation and elongation during chromosome replication
Mic7113_6199	COG5002	protein histidine kinase activity
Mic7113_6200	COG0151	Belongs to the GarS family
Mic7113_6201	COG0415	Belongs to the DNA photolyase family
Mic7113_6203	COG0494	nUDIX hydrolase
Mic7113_6204	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Mic7113_6205	COG0525	valine-tRNA ligase activity
Mic7113_6207	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_6207	COG0515	serine threonine protein kinase
Mic7113_6208	COG0515	serine threonine protein kinase
Mic7113_6208	COG1357	PFAM Pentapeptide repeats (8 copies)
Mic7113_6209	COG0515	serine threonine protein kinase
Mic7113_6209	COG3266	domain, Protein
Mic7113_6214	COG1104	cysteine desulfurase activity
Mic7113_6215	COG1530	ribonuclease E activity
Mic7113_6216	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Mic7113_6219	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Mic7113_6220	COG0051	transcription antitermination factor activity, RNA binding
Mic7113_6221	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Mic7113_6222	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Mic7113_6224	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Mic7113_6225	COG0316	Belongs to the HesB IscA family
Mic7113_6228	COG0067	glutamate synthase
Mic7113_6228	COG0069	glutamate synthase activity
Mic7113_6228	COG0070	glutamate synthase
Mic7113_6231	COG0489	protein tyrosine kinase activity
Mic7113_6236	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Mic7113_6237	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Mic7113_6239	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Mic7113_6243	COG0217	transcriptional regulatory protein
Mic7113_6244	COG0745	RESPONSE REGULATOR receiver
Mic7113_6246	COG5002	protein histidine kinase activity
Mic7113_6246	COG3850	Histidine kinase
Mic7113_6247	COG0745	RESPONSE REGULATOR receiver
Mic7113_6250	COG0837	glucose binding
Mic7113_6253	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Mic7113_6255	COG1194	a g-specific adenine glycosylase
Mic7113_6256	COG2205	protein histidine kinase activity
Mic7113_6257	COG1543	Belongs to the glycosyl hydrolase 57 family
Mic7113_6269	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Mic7113_6271	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
Mic7113_6272	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Mic7113_6273	COG2203	Gaf domain
Mic7113_6273	COG5001	Diguanylate cyclase
Mic7113_6273	COG4251	negative regulation of phosphorylation
Mic7113_6273	COG3706	GGDEF domain
Mic7113_6274	COG2217	Heavy metal translocating P-type atpase
Mic7113_6278	COG4585	Histidine kinase
Mic7113_6279	COG2197	response regulator
Mic7113_6285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Mic7113_6287	COG3536	Protein conserved in bacteria
Mic7113_6288	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Mic7113_6289	COG0556	nucleotide-excision repair
Mic7113_6295	COG3977	Valine--pyruvate aminotransferase
Mic7113_6301	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Mic7113_6302	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Mic7113_6306	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Mic7113_6310	COG3854	ATPases associated with a variety of cellular activities
Mic7113_6317	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Mic7113_6318	COG0088	Forms part of the polypeptide exit tunnel
Mic7113_6319	COG0089	rRNA binding
Mic7113_6320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Mic7113_6321	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Mic7113_6322	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Mic7113_6323	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Mic7113_6324	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Mic7113_6325	COG0255	Belongs to the universal ribosomal protein uL29 family
Mic7113_6326	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Mic7113_6327	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Mic7113_6328	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Mic7113_6329	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Mic7113_6330	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Mic7113_6331	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Mic7113_6332	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Mic7113_6333	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Mic7113_6334	COG0200	Binds to the 23S rRNA
Mic7113_6335	COG0201	protein transport
Mic7113_6336	COG0563	adenylate kinase activity
Mic7113_6337	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Mic7113_6339	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Mic7113_6340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Mic7113_6341	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Mic7113_6342	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Mic7113_6343	COG0202	RNA polymerase activity
Mic7113_6344	COG0203	ribosomal protein L17
Mic7113_6345	COG0101	tRNA pseudouridine synthase activity
Mic7113_6346	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Mic7113_6347	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Mic7113_6348	COG0254	rRNA binding
Mic7113_6349	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Mic7113_6353	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Mic7113_6354	COG2211	Major facilitator Superfamily
Mic7113_6355	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Mic7113_6363	COG1695	Transcriptional regulator
Mic7113_6364	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Mic7113_6366	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Mic7113_6367	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Mic7113_6367	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Mic7113_6369	COG2319	Wd-40 repeat
Mic7113_6369	COG3903	Transcriptional regulator
Mic7113_6374	COG2723	6-phospho-beta-galactosidase activity
Mic7113_6375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Mic7113_6377	COG0488	(ABC) transporter
Mic7113_6380	COG2066	Belongs to the glutaminase family
Mic7113_6383	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Mic7113_6384	COG0443	Heat shock 70 kDa protein
Mic7113_6385	COG0484	heat shock protein binding
Mic7113_6390	COG0018	arginyl-trna synthetase
Mic7113_6392	COG0242	peptide deformylase activity
Mic7113_6419	COG1475	DNA binding
Mic7113_6420	COG1192	Involved in chromosome partitioning
Mic7113_6429	COG4974	Belongs to the 'phage' integrase family
Mic7113_6436	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Mic7113_6438	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Mic7113_6440	COG0515	serine threonine protein kinase
Mic7113_6440	COG2815	serine threonine protein kinase
Mic7113_6445	COG1061	Type III restriction enzyme res subunit
Mic7113_6450	COG0189	ligase activity
Mic7113_6453	COG4249	Peptidase C14 caspase catalytic subunit p20
Mic7113_6453	COG2319	Wd-40 repeat
Mic7113_6464	COG1111	helicase
Mic7113_6464	COG1205	dead DEAH box helicase
Mic7113_6470	COG0592	DNA-directed DNA polymerase activity
Mic7113_6498	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Mic7113_6506	COG4974	Belongs to the 'phage' integrase family
Mic7113_6510	COG4115	mRNA cleavage
Mic7113_6511	COG2161	toxin-antitoxin pair type II binding
Mic7113_6521	COG1215	transferase activity, transferring glycosyl groups
Mic7113_6522	COG0784	Response regulator, receiver
Mic7113_6525	COG2203	Gaf domain
Mic7113_6525	COG0840	transmembrane signaling receptor activity
Mic7113_6526	COG2198	Histidine kinase
Mic7113_6526	COG0784	Response regulator, receiver
Mic7113_6526	COG0643	Histidine kinase
Mic7113_6539	COG0438	transferase activity, transferring glycosyl groups
Mic7113_6540	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Mic7113_6544	COG1192	Involved in chromosome partitioning
Mic7113_6559	COG1091	dTDP-4-dehydrorhamnose reductase activity
Mic7113_6573	COG0489	protein tyrosine kinase activity
Mic7113_6575	COG4221	oxidoreductase activity
Mic7113_6624	COG1468	defense response to virus
Mic7113_6624	COG1518	maintenance of DNA repeat elements
Mic7113_6629	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Mic7113_6632	COG0270	DNA (cytosine-5-)-methyltransferase activity
Mic7113_6649	COG2319	Wd-40 repeat
Mic7113_6649	COG1672	PFAM Archaeal ATPase
Mic7113_6650	COG1672	PFAM Archaeal ATPase
Mic7113_6650	COG2319	Wd-40 repeat
Mic7113_6651	COG2319	Wd-40 repeat
Mic7113_6651	COG1672	PFAM Archaeal ATPase
Mic7113_6672	COG1192	Involved in chromosome partitioning
Mic7113_6673	COG0367	asparagine synthase
Mic7113_6676	COG0071	Belongs to the small heat shock protein (HSP20) family
Mic7113_6677	COG4974	Belongs to the 'phage' integrase family
Mic7113_6684	COG2329	Antibiotic biosynthesis monooxygenase
Mic7113_6699	COG4249	Peptidase C14 caspase catalytic subunit p20
Mic7113_6699	COG2319	Wd-40 repeat
Mic7113_6704	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Mic7113_6711	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Mic7113_6715	COG1032	radical SAM domain protein
Mic7113_6717	COG1192	Involved in chromosome partitioning
Mic7113_6738	COG1695	Transcriptional regulator
Mic7113_6740	COG1160	GTP binding
Mic7113_6741	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Mic7113_6745	COG0732	type I restriction modification DNA specificity domain
Mic7113_6747	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Mic7113_6753	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Mic7113_6754	COG4974	Belongs to the 'phage' integrase family
Mic7113_6783	COG0720	synthase
Mic7113_6791	COG1694	Mazg nucleotide pyrophosphohydrolase
Mic7113_6800	COG1475	DNA binding
Mic7113_6801	COG1192	Involved in chromosome partitioning