locus-tag	class	description
IPI58_00030	COG3299	homolog of phage Mu protein gp47
IPI58_00035	COG3778	Protein conserved in bacteria
IPI58_00100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IPI58_00135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IPI58_00145	COG2857	Cytochrome c1
IPI58_00145	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IPI58_00150	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPI58_00155	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IPI58_00165	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IPI58_00170	COG1227	inorganic diphosphatase activity
IPI58_00175	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IPI58_00180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IPI58_00195	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IPI58_00225	COG2989	Protein conserved in bacteria
IPI58_00240	COG0563	adenylate kinase activity
IPI58_00245	COG1131	(ABC) transporter
IPI58_00275	COG0416	fatty acid biosynthetic process
IPI58_00280	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IPI58_00320	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IPI58_00325	COG0483	inositol monophosphate 1-phosphatase activity
IPI58_00340	COG0488	(ABC) transporter
IPI58_00345	COG0356	it plays a direct role in the translocation of protons across the membrane
IPI58_00355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IPI58_00375	COG0494	nUDIX hydrolase
IPI58_00390	COG0024	Methionine aminopeptidase
IPI58_00395	COG2003	Belongs to the UPF0758 family
IPI58_00400	COG0384	phenazine biosynthesis protein PhzF
IPI58_00415	COG1595	DNA-templated transcription, initiation
IPI58_00450	COG0776	regulation of translation
IPI58_00455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IPI58_00475	COG0556	nucleotide-excision repair
IPI58_00490	COG0463	Glycosyl transferase, family 2
IPI58_00495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IPI58_00500	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IPI58_00515	COG1749	Flagellar hook protein flgE
IPI58_00520	COG0528	UMP kinase activity
IPI58_00525	COG2264	protein methyltransferase activity
IPI58_00575	COG1061	Type III restriction enzyme res subunit
IPI58_00820	COG0582	viral genome integration into host DNA
IPI58_00830	COG2274	protein secretion by the type I secretion system
IPI58_00870	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IPI58_00890	COG1132	(ABC) transporter
IPI58_00895	COG1073	alpha beta
IPI58_00900	COG4172	Belongs to the ABC transporter superfamily
IPI58_00910	COG2124	cytochrome p450
IPI58_00930	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IPI58_00960	COG2945	thiolester hydrolase activity
IPI58_00965	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IPI58_00970	COG0124	histidyl-tRNA synthetase
IPI58_00980	COG1684	flagellar biosynthetic protein fliR
IPI58_00985	COG1987	bacterial-type flagellum assembly
IPI58_00995	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPI58_01000	COG0564	pseudouridine synthase activity
IPI58_01010	COG0717	Belongs to the dCTP deaminase family
IPI58_01030	COG2988	succinylglutamate desuccinylase activity
IPI58_01060	COG0250	Participates in transcription elongation, termination and antitermination
IPI58_01075	COG0840	transmembrane signaling receptor activity
IPI58_01075	COG0840	transmembrane signaling receptor activity
IPI58_01125	COG0126	phosphoglycerate kinase activity
IPI58_01130	COG3243	poly(R)-hydroxyalkanoic acid synthase
IPI58_01145	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPI58_01150	COG1250	3-hydroxyacyl-CoA dehydrogenase
IPI58_01165	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPI58_01200	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IPI58_01210	COG0646	methionine synthase
IPI58_01210	COG1410	methionine synthase
IPI58_01225	COG0513	Belongs to the DEAD box helicase family
IPI58_01245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IPI58_01270	COG0400	carboxylic ester hydrolase activity
IPI58_01285	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IPI58_01290	COG1846	Transcriptional regulator
IPI58_01320	COG2096	Adenosyltransferase
IPI58_01330	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IPI58_01335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPI58_01340	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPI58_01350	COG0649	NAD binding
IPI58_01355	COG0651	ATP synthesis coupled electron transport
IPI58_01365	COG0650	Formate hydrogenlyase subunit 4
IPI58_01370	COG0651	ATP synthesis coupled electron transport
IPI58_01395	COG2204	response regulator
IPI58_01465	COG2201	protein-glutamate methylesterase activity
IPI58_01470	COG2201	protein-glutamate methylesterase activity
IPI58_01475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IPI58_01480	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IPI58_01495	COG0492	ferredoxin-NADP+ reductase activity
IPI58_01505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IPI58_01515	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IPI58_01520	COG2885	chlorophyll binding
IPI58_01555	COG0784	Response regulator, receiver
IPI58_01555	COG5002	protein histidine kinase activity
IPI58_01555	COG2205	protein histidine kinase activity
IPI58_01565	COG0552	protein localization to endoplasmic reticulum
IPI58_01580	COG0552	protein localization to endoplasmic reticulum
IPI58_01595	COG1131	(ABC) transporter
IPI58_01605	COG1674	ftsk spoiiie
IPI58_01620	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IPI58_01620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IPI58_01630	COG0511	ligase activity, forming carbon-carbon bonds
IPI58_01650	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IPI58_01655	COG0330	HflC and HflK could
IPI58_01670	COG0741	lytic transglycosylase activity
IPI58_01675	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IPI58_01680	COG1034	ATP synthesis coupled electron transport
IPI58_01695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IPI58_01700	COG0204	Acyl-transferase
IPI58_01700	COG0318	PFAM AMP-dependent synthetase and ligase
IPI58_01715	COG0497	DNA recombination
IPI58_01720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IPI58_01725	COG0469	pyruvate kinase activity
IPI58_01740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPI58_01750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPI58_01755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPI58_01790	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IPI58_01795	COG1420	regulation of RNA biosynthetic process
IPI58_01820	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IPI58_01830	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IPI58_01855	COG0268	Binds directly to 16S ribosomal RNA
IPI58_01860	COG0242	peptide deformylase activity
IPI58_01870	COG1678	Uncharacterized ACR, COG1678
IPI58_01880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IPI58_01885	COG2116	formate transmembrane transporter activity
IPI58_01940	COG1185	polyribonucleotide nucleotidyltransferase activity
IPI58_01945	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IPI58_01955	COG0793	Belongs to the peptidase S41A family
IPI58_01960	COG0628	permease
IPI58_01980	COG0803	Belongs to the bacterial solute-binding protein 9 family
IPI58_01990	COG1121	(ABC) transporter
IPI58_02005	COG0745	RESPONSE REGULATOR receiver
IPI58_02010	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IPI58_02020	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IPI58_02025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPI58_02030	COG0805	protein transport
IPI58_02040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPI58_02065	COG1192	Involved in chromosome partitioning
IPI58_02070	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IPI58_02080	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IPI58_02085	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IPI58_02105	COG2927	DNA polymerase III (CHI subunit)
IPI58_02115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IPI58_02130	COG2274	protein secretion by the type I secretion system
IPI58_02135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IPI58_02140	COG0649	NAD binding
IPI58_02150	COG0281	malic enzyme
IPI58_02150	COG0280	phosphate acetyltransferase
IPI58_02155	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IPI58_02160	COG2202	Pas domain
IPI58_02160	COG2205	protein histidine kinase activity
IPI58_02165	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IPI58_02180	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IPI58_02190	COG5001	Diguanylate cyclase
IPI58_02190	COG3706	GGDEF domain
IPI58_02190	COG2203	Gaf domain
IPI58_02190	COG4251	negative regulation of phosphorylation
IPI58_02200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IPI58_02215	COG0792	nuclease activity
IPI58_02220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IPI58_02235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IPI58_02260	COG0463	Glycosyl transferase, family 2
IPI58_02270	COG1758	RNA polymerase activity
IPI58_02280	COG0736	holo-[acyl-carrier-protein] synthase activity
IPI58_02285	COG0681	Belongs to the peptidase S26 family
IPI58_02290	COG0571	ribonuclease III activity
IPI58_02300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IPI58_02305	COG1322	Protein conserved in bacteria
IPI58_02325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IPI58_02355	COG0835	chemotaxis
IPI58_02360	COG0643	Histidine kinase
IPI58_02360	COG2198	Histidine kinase
IPI58_02360	COG0784	Response regulator, receiver
IPI58_02385	COG0439	Biotin carboxylase
IPI58_02405	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IPI58_02420	COG0071	Belongs to the small heat shock protein (HSP20) family
IPI58_02425	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IPI58_02435	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IPI58_02455	COG1028	Short-chain dehydrogenase reductase Sdr
IPI58_02465	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPI58_02470	COG0085	RNA polymerase activity
IPI58_02475	COG0222	ribosome binding
IPI58_02480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IPI58_02500	COG0745	RESPONSE REGULATOR receiver
IPI58_02505	COG2198	Histidine kinase
IPI58_02505	COG0643	Histidine kinase
IPI58_02515	COG0840	transmembrane signaling receptor activity
IPI58_02520	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IPI58_02525	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
IPI58_02535	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IPI58_02540	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IPI58_02550	COG1558	bacterial-type flagellum-dependent cell motility
IPI58_02555	COG1677	Flagellar hook-basal body complex protein FliE
IPI58_02560	COG0590	tRNA wobble adenosine to inosine editing
IPI58_02565	COG0745	RESPONSE REGULATOR receiver
IPI58_02575	COG1657	PFAM Prenyltransferase squalene oxidase
IPI58_02590	COG0443	Heat shock 70 kDa protein
IPI58_02600	COG0012	GTP binding
IPI58_02605	COG0193	aminoacyl-tRNA hydrolase activity
IPI58_02610	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IPI58_02625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IPI58_02630	COG2967	ApaG domain
IPI58_02635	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IPI58_02645	COG4786	Flagellar basal body rod
IPI58_02650	COG4786	Flagellar basal body rod
IPI58_02655	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPI58_02665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPI58_02705	COG3956	TIGRFAM MazG family protein
IPI58_02710	COG0596	Alpha beta hydrolase
IPI58_02715	COG0443	Heat shock 70 kDa protein
IPI58_02740	COG0284	orotidine-5'-phosphate decarboxylase activity
IPI58_02745	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IPI58_02775	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IPI58_02780	COG0006	proline dipeptidase activity
IPI58_02785	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IPI58_02800	COG0189	ligase activity
IPI58_02800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IPI58_02805	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IPI58_02805	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IPI58_02845	COG0415	Belongs to the DNA photolyase family
IPI58_02860	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IPI58_02880	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IPI58_02885	COG0101	tRNA pseudouridine synthase activity
IPI58_02890	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IPI58_02905	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IPI58_02935	COG0629	single-stranded DNA binding
IPI58_02955	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IPI58_02965	COG0539	negative regulation of cytoplasmic translation
IPI58_02970	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IPI58_02980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IPI58_02985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPI58_02990	COG1214	PFAM Peptidase M22, glycoprotease
IPI58_02995	COG1704	LemA family
IPI58_03000	COG0501	Belongs to the peptidase M48B family
IPI58_03010	COG1217	gtp-binding protein TYPA
IPI58_03020	COG0799	negative regulation of ribosome biogenesis
IPI58_03025	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IPI58_03030	COG1338	Plays a role in the flagellum-specific transport system
IPI58_03100	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IPI58_03105	COG0688	phosphatidylethanolamine metabolic process
IPI58_03150	COG1381	Involved in DNA repair and RecF pathway recombination
IPI58_03155	COG1132	(ABC) transporter
IPI58_03170	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IPI58_03180	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IPI58_03185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IPI58_03190	COG0653	protein targeting
IPI58_03215	COG1137	ATPase activity
IPI58_03220	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IPI58_03250	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IPI58_03280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IPI58_03290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPI58_03295	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IPI58_03310	COG1160	GTP binding
IPI58_03325	COG0204	Acyl-transferase
IPI58_03340	COG4999	Histidine kinase
IPI58_03340	COG3850	Histidine kinase
IPI58_03340	COG3437	response regulator, receiver
IPI58_03340	COG2205	protein histidine kinase activity
IPI58_03375	COG0488	(ABC) transporter
IPI58_03400	COG0564	pseudouridine synthase activity
IPI58_03410	COG0612	Peptidase, M16
IPI58_03415	COG0612	Peptidase, M16
IPI58_03425	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IPI58_03430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IPI58_03435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IPI58_03445	COG0138	bifunctional purine biosynthesis protein purh
IPI58_03450	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IPI58_03455	COG1702	phosphate starvation-inducible protein PhoH
IPI58_03480	COG1472	Belongs to the glycosyl hydrolase 3 family
IPI58_03485	COG1994	Peptidase M50
IPI58_03490	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IPI58_03495	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IPI58_03500	COG4953	penicillin-binding protein 1C
IPI58_03505	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IPI58_03510	COG4957	zinc ion binding
IPI58_03515	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IPI58_03525	COG1007	ATP synthesis coupled electron transport
IPI58_03535	COG0713	ATP synthesis coupled electron transport
IPI58_03545	COG0513	Belongs to the DEAD box helicase family
IPI58_03550	COG0849	cell division
IPI58_03555	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IPI58_03560	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IPI58_03565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IPI58_03570	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IPI58_03580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPI58_03585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IPI58_03605	COG2001	Belongs to the MraZ family
IPI58_03615	COG0752	glycyl-tRNA synthetase alpha subunit
IPI58_03620	COG0751	glycine-tRNA ligase activity
IPI58_03640	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IPI58_03645	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IPI58_03650	COG0202	RNA polymerase activity
IPI58_03655	COG0203	ribosomal protein L17
IPI58_03685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPI58_03695	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPI58_03700	COG0482	sulfurtransferase activity
IPI58_03755	COG0859	PFAM glycosyl transferase family 9
IPI58_03760	COG0438	transferase activity, transferring glycosyl groups
IPI58_03775	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IPI58_03790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IPI58_03795	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPI58_03800	COG0154	amidase activity
IPI58_03810	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
IPI58_03815	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IPI58_03825	COG0842	Transport permease protein
IPI58_03845	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IPI58_03855	COG1923	regulation of RNA biosynthetic process
IPI58_03860	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IPI58_03880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IPI58_03920	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IPI58_03925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IPI58_03930	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IPI58_03935	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPI58_03970	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IPI58_03975	COG2204	response regulator
IPI58_03985	COG1538	Outer membrane efflux protein
IPI58_03995	COG2771	luxR family
IPI58_04020	COG0840	transmembrane signaling receptor activity
IPI58_04025	COG0784	Response regulator, receiver
IPI58_04025	COG2205	protein histidine kinase activity
IPI58_04025	COG5002	protein histidine kinase activity
IPI58_04030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IPI58_04035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IPI58_04040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPI58_04050	COG3932	Exopolysaccharide synthesis, ExoD
IPI58_04055	COG0316	Belongs to the HesB IscA family
IPI58_04060	COG2151	metal-sulfur cluster biosynthetic enzyme
IPI58_04065	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IPI58_04080	COG3750	Belongs to the UPF0335 family
IPI58_04090	COG1132	(ABC) transporter
IPI58_04095	COG0822	iron-sulfur transferase activity
IPI58_04115	COG0768	penicillin binding
IPI58_04120	COG1214	PFAM Peptidase M22, glycoprotease
IPI58_04120	COG0456	acetyltransferase
IPI58_04140	COG4174	ABC transporter (Permease)
IPI58_04145	COG2867	negative regulation of translational initiation
IPI58_04160	COG4695	Portal protein
IPI58_04255	COG3550	peptidyl-serine autophosphorylation
IPI58_04260	COG1396	sequence-specific DNA binding
IPI58_04285	COG1238	metal cluster binding
IPI58_04290	COG4239	(ABC) transporter, permease
IPI58_04300	COG2070	2-Nitropropane dioxygenase
IPI58_04310	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPI58_04330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPI58_04355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IPI58_04420	COG0308	aminopeptidase N
IPI58_04435	COG1294	oxidase, subunit
IPI58_04440	COG1271	oxidase subunit
IPI58_04445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IPI58_04460	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IPI58_04470	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IPI58_04485	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IPI58_04490	COG1196	nuclear chromosome segregation
IPI58_04495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IPI58_04505	COG1194	a g-specific adenine glycosylase
IPI58_04510	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IPI58_04515	COG1215	transferase activity, transferring glycosyl groups
IPI58_04520	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IPI58_04530	COG1573	uracil-dna glycosylase
IPI58_04535	COG4974	Belongs to the 'phage' integrase family
IPI58_04545	COG0772	Belongs to the SEDS family
IPI58_04555	COG0803	Belongs to the bacterial solute-binding protein 9 family
IPI58_04560	COG0443	Heat shock 70 kDa protein
IPI58_04580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IPI58_04660	COG1061	Type III restriction enzyme res subunit
IPI58_04780	COG0488	(ABC) transporter
IPI58_04785	COG0588	phosphoglycerate mutase activity
IPI58_04860	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IPI58_04875	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IPI58_04905	COG3210	domain, Protein
IPI58_04940	COG1309	transcriptional regulator
IPI58_04955	COG0577	efflux transmembrane transporter activity
IPI58_04955	COG1136	(ABC) transporter
IPI58_04970	COG2827	Endonuclease containing a URI domain
IPI58_05000	COG0210	DNA helicase
IPI58_05040	COG0742	ribosomal rna small subunit methyltransferase
IPI58_05045	COG1187	pseudouridine synthase activity
IPI58_05050	COG0217	transcriptional regulatory protein
IPI58_05060	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IPI58_05080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IPI58_05095	COG0180	Tryptophanyl-tRNA synthetase
IPI58_05105	COG0180	Tryptophanyl-tRNA synthetase
IPI58_05120	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IPI58_05135	COG0706	membrane insertase activity
IPI58_05140	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IPI58_05145	COG0594	ribonuclease P activity
IPI58_05170	COG0776	regulation of translation
IPI58_05185	COG0328	RNA-DNA hybrid ribonuclease activity
IPI58_05215	COG2835	tetraacyldisaccharide 4'-kinase activity
IPI58_05235	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IPI58_05245	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPI58_05270	COG0233	cytoplasmic translational termination
IPI58_05305	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IPI58_05310	COG0459	protein refolding
IPI58_05340	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IPI58_05370	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IPI58_05380	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IPI58_05390	COG0052	Belongs to the universal ribosomal protein uS2 family
IPI58_05400	COG0215	cysteine-tRNA ligase activity
IPI58_05415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPI58_05420	COG0456	acetyltransferase
IPI58_05420	COG0454	-acetyltransferase
IPI58_05430	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IPI58_05455	COG0640	Transcriptional regulator
IPI58_05485	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IPI58_05495	COG0778	Nitroreductase
IPI58_05510	COG0438	transferase activity, transferring glycosyl groups
IPI58_05515	COG1519	Transferase
IPI58_05520	COG1663	tetraacyldisaccharide 4'-kinase activity
IPI58_05530	COG1570	exodeoxyribonuclease VII activity
IPI58_05555	COG0670	Belongs to the BI1 family
IPI58_05575	COG0783	Belongs to the Dps family
IPI58_05585	COG0287	Prephenate dehydrogenase
IPI58_05585	COG1605	Chorismate mutase
IPI58_05590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IPI58_05600	COG0312	modulator of DNA gyrase
IPI58_05630	COG5442	Flagellar protein FlaF
IPI58_05640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IPI58_05645	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPI58_05655	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IPI58_05670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IPI58_05680	COG3040	lipid binding
IPI58_05695	COG3177	Filamentation induced by cAMP protein fic
IPI58_05700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IPI58_05760	COG0124	histidyl-tRNA synthetase
IPI58_05765	COG0124	histidyl-tRNA synthetase
IPI58_05780	COG1957	nucleoside hydrolase
IPI58_05785	COG0483	inositol monophosphate 1-phosphatase activity
IPI58_05790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPI58_05800	COG2988	succinylglutamate desuccinylase activity
IPI58_05810	COG3772	lysozyme
IPI58_06015	COG1061	Type III restriction enzyme res subunit
IPI58_06105	COG0825	malonyl-CoA metabolic process
IPI58_06135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPI58_06140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPI58_06150	COG5001	Diguanylate cyclase
IPI58_06150	COG3300	MHYT domain
IPI58_06170	COG0037	tRNA processing
IPI58_06190	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IPI58_06215	COG0300	oxidoreductase activity
IPI58_06230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IPI58_06265	COG0779	Required for maturation of 30S ribosomal subunits
IPI58_06280	COG1181	Belongs to the D-alanine--D-alanine ligase family
IPI58_06310	COG2226	methyltransferase
IPI58_06315	COG1573	uracil-dna glycosylase
IPI58_06320	COG0859	PFAM glycosyl transferase family 9
IPI58_06325	COG0438	transferase activity, transferring glycosyl groups
IPI58_06330	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IPI58_06335	COG3494	Protein of unknown function (DUF1009)
IPI58_06345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IPI58_06355	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IPI58_06360	COG0750	zinc metalloprotease
IPI58_06365	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IPI58_06370	COG1040	competence protein
IPI58_06375	COG0494	nUDIX hydrolase
IPI58_06400	COG0167	dihydroorotate dehydrogenase activity
IPI58_06405	COG1981	membrane
IPI58_06415	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IPI58_06420	COG0237	dephospho-CoA kinase activity
IPI58_06425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IPI58_06455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IPI58_06460	COG3023	N-Acetylmuramoyl-L-alanine amidase
IPI58_06475	COG0445	tRNA wobble uridine modification
IPI58_06530	COG0318	PFAM AMP-dependent synthetase and ligase
IPI58_06535	COG1278	Cold shock
IPI58_06550	COG0105	UTP biosynthetic process
IPI58_06555	COG1051	belongs to the nudix hydrolase family
IPI58_06560	COG1686	Belongs to the peptidase S11 family
IPI58_06565	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IPI58_06700	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IPI58_06705	COG2204	response regulator
IPI58_06710	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IPI58_06720	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IPI58_06725	COG1766	The M ring may be actively involved in energy transduction
IPI58_06735	COG0758	DNA mediated transformation
IPI58_06740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IPI58_06750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPI58_06800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IPI58_06805	COG0022	dehydrogenase e1 component
IPI58_06805	COG0508	dehydrogenase complex catalyzes the overall conversion of
IPI58_06820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IPI58_06850	COG2205	protein histidine kinase activity
IPI58_06870	COG2951	lytic endotransglycosylase activity
IPI58_06910	COG0616	signal peptide processing
IPI58_06930	COG3206	protein involved in exopolysaccharide biosynthesis
IPI58_06930	COG0489	protein tyrosine kinase activity
IPI58_06935	COG1596	polysaccharide export
IPI58_06955	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IPI58_06985	COG3340	Belongs to the peptidase S51 family
IPI58_06990	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IPI58_06995	COG1562	ergosterol biosynthetic process
IPI58_07000	COG1562	ergosterol biosynthetic process
IPI58_07005	COG3158	transport of potassium into the cell
IPI58_07010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IPI58_07015	COG2373	Large extracellular alpha-helical protein
IPI58_07025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IPI58_07035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IPI58_07065	COG1253	flavin adenine dinucleotide binding
IPI58_07095	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IPI58_07105	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPI58_07115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IPI58_07120	COG0581	inorganic phosphate transmembrane transporter activity
IPI58_07125	COG0573	inorganic phosphate transmembrane transporter activity
IPI58_07130	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IPI58_07155	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPI58_07165	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IPI58_07175	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IPI58_07205	COG4591	ABC-type transport system involved in lipoprotein release permease component
IPI58_07220	COG0343	queuine tRNA-ribosyltransferase activity
IPI58_07225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IPI58_07230	COG3177	Filamentation induced by cAMP protein fic
IPI58_07240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IPI58_07255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IPI58_07260	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IPI58_07295	COG0322	excinuclease ABC activity
IPI58_07305	COG0248	Ppx GppA phosphatase
IPI58_07310	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IPI58_07325	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IPI58_07395	COG0739	heme binding
IPI58_07430	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IPI58_07435	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IPI58_07450	COG3243	poly(R)-hydroxyalkanoic acid synthase
IPI58_07475	COG0438	transferase activity, transferring glycosyl groups
IPI58_07485	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IPI58_07490	COG0501	Belongs to the peptidase M48B family
IPI58_07500	COG0824	Thioesterase
IPI58_07520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IPI58_07550	COG2885	chlorophyll binding
IPI58_07550	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IPI58_07555	COG0009	L-threonylcarbamoyladenylate synthase
IPI58_07585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IPI58_07595	COG0658	competence protein
IPI58_07595	COG2333	competence protein COMEC
IPI58_07605	COG1028	Short-chain dehydrogenase reductase Sdr
IPI58_07645	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IPI58_07650	COG0084	hydrolase, TatD family'
IPI58_07665	COG0481	GTPase activity
IPI58_07690	COG0745	RESPONSE REGULATOR receiver
IPI58_07695	COG1660	Displays ATPase and GTPase activities
IPI58_07700	COG2255	four-way junction helicase activity
IPI58_07705	COG0632	four-way junction helicase activity
IPI58_07710	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IPI58_07715	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IPI58_07720	COG0741	lytic transglycosylase activity
IPI58_07750	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IPI58_07760	COG1530	ribonuclease E activity
IPI58_07765	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IPI58_07780	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IPI58_07780	COG0662	Cupin 2, conserved barrel domain protein
IPI58_07785	COG1872	DUF167
IPI58_07795	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IPI58_07800	COG0049	tRNA binding
IPI58_07810	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IPI58_07815	COG0051	transcription antitermination factor activity, RNA binding
IPI58_07835	COG0089	rRNA binding
IPI58_07840	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IPI58_07845	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IPI58_07850	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IPI58_07855	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IPI58_07860	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IPI58_07865	COG0255	Belongs to the universal ribosomal protein uL29 family
IPI58_07870	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IPI58_07875	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IPI58_07880	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IPI58_07890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPI58_07895	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IPI58_07900	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IPI58_07910	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IPI58_07915	COG1841	ribosomal large subunit assembly
IPI58_07920	COG0200	Binds to the 23S rRNA
IPI58_07935	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IPI58_07945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPI58_07950	COG0719	Fe-S assembly protein
IPI58_07955	COG0396	ATPase activity
IPI58_07970	COG0719	Fe-S assembly protein
IPI58_07995	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IPI58_08035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IPI58_08085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IPI58_08110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IPI58_08125	COG0542	response to heat
IPI58_08130	COG2884	Cell division ATP-binding protein ftsE
IPI58_08135	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IPI58_08160	COG1496	oxidoreductase activity
IPI58_08165	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IPI58_08180	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IPI58_08180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IPI58_08190	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IPI58_08210	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPI58_08220	COG0330	HflC and HflK could
IPI58_08225	COG0330	HflC and HflK could
IPI58_08235	COG1692	metallophosphoesterase
IPI58_08255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IPI58_08260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IPI58_08270	COG4166	transmembrane transport
IPI58_08275	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IPI58_08280	COG1360	Flagellar Motor Protein
IPI58_08285	COG0745	RESPONSE REGULATOR receiver
IPI58_08300	COG0436	Aminotransferase
IPI58_08330	COG1862	Preprotein translocase
IPI58_08335	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPI58_08340	COG0612	Peptidase, M16
IPI58_08355	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IPI58_08485	COG0616	signal peptide processing
IPI58_08590	COG2217	Heavy metal translocating P-type atpase
IPI58_08595	COG1937	Protein conserved in bacteria
IPI58_08640	COG1595	DNA-templated transcription, initiation
IPI58_08695	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IPI58_08810	COG0124	histidyl-tRNA synthetase
IPI58_08815	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IPI58_08820	COG1518	maintenance of DNA repeat elements
IPI58_08860	COG0071	Belongs to the small heat shock protein (HSP20) family
IPI58_08865	COG0678	peroxiredoxin activity
IPI58_08875	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IPI58_08880	COG0142	geranyltranstransferase activity
IPI58_08885	COG1722	exodeoxyribonuclease VII activity
IPI58_08895	COG0248	Ppx GppA phosphatase
IPI58_08895	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IPI58_08905	COG4520	surface antigen
IPI58_08915	COG0861	Integral membrane protein TerC family
IPI58_08920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IPI58_08930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IPI58_08935	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IPI58_08940	COG0081	regulation of translation
IPI58_08965	COG3827	peptidoglycan binding
IPI58_08980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPI58_08980	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPI58_09000	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
IPI58_09005	COG1024	Enoyl-CoA hydratase
IPI58_09020	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPI58_09025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IPI58_09030	COG0228	four-way junction DNA binding
IPI58_09040	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IPI58_09045	COG0336	Belongs to the RNA methyltransferase TrmD family
IPI58_09050	COG0335	large ribosomal subunit rRNA binding
IPI58_09070	COG0187	DNA topoisomerase II activity
IPI58_09085	COG0442	prolyl-tRNA aminoacylation
IPI58_09090	COG0714	Associated with various cellular activities
IPI58_09095	COG1126	abc transporter atp-binding protein
IPI58_09110	COG0495	leucyl-tRNA aminoacylation
IPI58_09115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPI58_09140	COG1619	proteins homologs of microcin C7 resistance protein MccF
IPI58_09150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IPI58_09175	COG0196	riboflavin kinase activity
IPI58_09200	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IPI58_09205	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IPI58_09210	COG4974	Belongs to the 'phage' integrase family
IPI58_09230	COG3108	Peptidase M15
IPI58_09260	COG3852	Histidine kinase
IPI58_09290	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IPI58_09295	COG1530	ribonuclease E activity
IPI58_09300	COG0424	maF-like protein
IPI58_09340	COG0642	Histidine kinase
IPI58_09345	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IPI58_09350	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IPI58_09355	COG2861	carbohydrate metabolic process
IPI58_09360	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IPI58_09365	COG1136	(ABC) transporter
IPI58_09370	COG1136	(ABC) transporter
IPI58_09370	COG0577	efflux transmembrane transporter activity
IPI58_09395	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IPI58_09400	COG2205	protein histidine kinase activity
IPI58_09420	COG0318	PFAM AMP-dependent synthetase and ligase
IPI58_09445	COG0574	Belongs to the PEP-utilizing enzyme family
IPI58_09445	COG3848	Pyruvate phosphate dikinase
IPI58_09450	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPI58_09460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IPI58_09475	COG3107	peptidoglycan biosynthetic process
IPI58_09480	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IPI58_09505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IPI58_09520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IPI58_09530	COG1253	flavin adenine dinucleotide binding
IPI58_09535	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IPI58_09540	COG1396	sequence-specific DNA binding
IPI58_09550	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IPI58_09555	COG3178	'Phosphotransferase
IPI58_09565	COG0494	nUDIX hydrolase
IPI58_09570	COG0181	hydroxymethylbilane synthase activity
IPI58_09595	COG1074	ATP-dependent DNA helicase activity
IPI58_09635	COG4964	Belongs to the GSP D family
IPI58_09650	COG0142	geranyltranstransferase activity
IPI58_09660	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IPI58_09665	COG0668	transmembrane transport
IPI58_09670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IPI58_09760	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
IPI58_09825	COG1475	DNA binding
IPI58_09830	COG3969	phosphoadenosine phosphosulfate
IPI58_09910	COG4386	tail sheath protein