locus-tag	class	description
H6849_00005	COG0187	DNA topoisomerase II activity
H6849_00020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H6849_00025	COG1121	(ABC) transporter
H6849_00035	COG1322	Protein conserved in bacteria
H6849_00040	COG4166	transmembrane transport
H6849_00045	COG4174	ABC transporter (Permease)
H6849_00050	COG4239	(ABC) transporter, permease
H6849_00055	COG4172	Belongs to the ABC transporter superfamily
H6849_00065	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H6849_00070	COG0571	ribonuclease III activity
H6849_00085	COG1007	ATP synthesis coupled electron transport
H6849_00090	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H6849_00095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H6849_00120	COG0463	Glycosyl transferase, family 2
H6849_00125	COG2271	Major facilitator Superfamily
H6849_00130	COG0113	porphobilinogen synthase activity
H6849_00165	COG0697	spore germination
H6849_00200	COG4695	Portal protein
H6849_00215	COG0330	HflC and HflK could
H6849_00250	COG0633	Ferredoxin
H6849_00270	COG0316	Belongs to the HesB IscA family
H6849_00275	COG0822	iron-sulfur transferase activity
H6849_00280	COG1104	cysteine desulfurase activity
H6849_00295	COG2945	thiolester hydrolase activity
H6849_00305	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H6849_00310	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H6849_00315	COG0517	IMP dehydrogenase activity
H6849_00315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H6849_00330	COG1137	ATPase activity
H6849_00335	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H6849_00345	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H6849_00355	COG0497	DNA recombination
H6849_00360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H6849_00365	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H6849_00370	COG0488	(ABC) transporter
H6849_00375	COG1722	exodeoxyribonuclease VII activity
H6849_00385	COG1496	oxidoreductase activity
H6849_00395	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H6849_00425	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H6849_00440	COG2271	Major facilitator Superfamily
H6849_00450	COG0670	Belongs to the BI1 family
H6849_00455	COG0544	peptidyl-prolyl cis-trans isomerase activity
H6849_00465	COG2814	Major facilitator Superfamily
H6849_00485	COG1132	(ABC) transporter
H6849_00500	COG0271	Belongs to the BolA IbaG family
H6849_00505	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H6849_00510	COG0022	dehydrogenase e1 component
H6849_00510	COG0508	dehydrogenase complex catalyzes the overall conversion of
H6849_00515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H6849_00520	COG0335	large ribosomal subunit rRNA binding
H6849_00535	COG0228	four-way junction DNA binding
H6849_00560	COG1324	tolerance protein
H6849_00570	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H6849_00580	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H6849_00585	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H6849_00590	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H6849_00605	COG0750	zinc metalloprotease
H6849_00610	COG4589	Belongs to the CDS family
H6849_00615	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H6849_00620	COG0233	cytoplasmic translational termination
H6849_00625	COG0528	UMP kinase activity
H6849_00630	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H6849_00635	COG0052	Belongs to the universal ribosomal protein uS2 family
H6849_00640	COG0037	tRNA processing
H6849_00645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H6849_00660	COG0745	RESPONSE REGULATOR receiver
H6849_00665	COG3202	ADP transmembrane transporter activity
H6849_00675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H6849_00680	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H6849_00685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H6849_00700	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H6849_00705	COG0193	aminoacyl-tRNA hydrolase activity
H6849_00710	COG0012	GTP binding
H6849_00715	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H6849_00720	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H6849_00725	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H6849_00730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H6849_00735	COG0330	HflC and HflK could
H6849_00740	COG0330	HflC and HflK could
H6849_00745	COG0489	protein tyrosine kinase activity
H6849_00790	COG0321	lipoyl(octanoyl) transferase activity
H6849_00885	COG5444	nuclease activity
H6849_00930	COG5444	nuclease activity
H6849_00945	COG2239	Acts as a magnesium transporter
H6849_00950	COG2885	chlorophyll binding
H6849_00970	COG0811	peptide transport
H6849_00980	COG0525	valine-tRNA ligase activity
H6849_01030	COG0736	holo-[acyl-carrier-protein] synthase activity
H6849_01040	COG0686	Belongs to the AlaDH PNT family
H6849_01045	COG2814	Major facilitator Superfamily
H6849_01080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H6849_01095	COG3118	belongs to the thioredoxin family
H6849_01100	COG0006	proline dipeptidase activity
H6849_01105	COG0793	Belongs to the peptidase S41A family
H6849_01105	COG4946	Tricorn protease homolog
H6849_01110	COG0567	Dehydrogenase, E1 component
H6849_01120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H6849_01130	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H6849_01140	COG2003	Belongs to the UPF0758 family
H6849_01150	COG0483	inositol monophosphate 1-phosphatase activity
H6849_01155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H6849_01175	COG0484	heat shock protein binding
H6849_01180	COG0647	UMP catabolic process
H6849_01205	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H6849_01215	COG0752	glycyl-tRNA synthetase alpha subunit
H6849_01220	COG0504	CTP synthase activity
H6849_01225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H6849_01235	COG1286	toxin biosynthetic process
H6849_01260	COG0142	geranyltranstransferase activity
H6849_01275	COG1968	undecaprenyl-diphosphatase activity
H6849_01290	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H6849_01295	COG1674	ftsk spoiiie
H6849_01315	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
H6849_01320	COG0343	queuine tRNA-ribosyltransferase activity
H6849_01330	COG2204	response regulator
H6849_01365	COG1435	thymidine kinase activity
H6849_01375	COG1570	exodeoxyribonuclease VII activity
H6849_01420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H6849_01440	COG3202	ADP transmembrane transporter activity
H6849_01445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H6849_01450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H6849_01455	COG1862	Preprotein translocase
H6849_01460	COG0739	heme binding
H6849_01460	COG0741	lytic transglycosylase activity
H6849_01460	COG1196	nuclear chromosome segregation
H6849_01465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H6849_01470	COG0776	regulation of translation
H6849_01475	COG0024	Methionine aminopeptidase
H6849_01485	COG1546	Belongs to the CinA family
H6849_01485	COG1058	Belongs to the CinA family
H6849_01500	COG0814	amino acid
H6849_01505	COG1217	gtp-binding protein TYPA
H6849_01530	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H6849_01540	COG4535	Mg2 and Co2 transporter CorC
H6849_01545	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H6849_01550	COG1702	phosphate starvation-inducible protein PhoH
H6849_01555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H6849_01560	COG4957	zinc ion binding
H6849_01570	COG2989	Protein conserved in bacteria
H6849_01580	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H6849_01615	COG0166	Belongs to the GPI family
H6849_01625	COG0612	Peptidase, M16
H6849_01640	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H6849_01645	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H6849_01655	COG0492	ferredoxin-NADP+ reductase activity
H6849_01660	COG0471	metal ion transport
H6849_01695	COG0508	dehydrogenase complex catalyzes the overall conversion of
H6849_01700	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
H6849_01720	COG0531	amino acid
H6849_01725	COG2814	Major facilitator Superfamily
H6849_01730	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H6849_01740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H6849_01745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H6849_01780	COG0653	protein targeting
H6849_01805	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H6849_01820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H6849_01865	COG0482	sulfurtransferase activity
H6849_01875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H6849_01885	COG1573	uracil-dna glycosylase
H6849_01905	COG0126	phosphoglycerate kinase activity
H6849_01910	COG0493	'glutamate synthase
H6849_01910	COG0543	2 iron, 2 sulfur cluster binding
H6849_01920	COG0194	GDP metabolic process
H6849_01950	COG0045	succinate-CoA ligase (ADP-forming) activity
H6849_01960	COG0606	chelatase, subunit chli
H6849_01975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H6849_01980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H6849_02010	COG0569	domain protein
H6849_02020	COG0316	Belongs to the HesB IscA family
H6849_02045	COG0217	transcriptional regulatory protein
H6849_02055	COG0632	four-way junction helicase activity
H6849_02060	COG2255	four-way junction helicase activity
H6849_02080	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H6849_02085	COG0792	nuclease activity
H6849_02095	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H6849_02100	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H6849_02125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H6849_02140	COG4974	Belongs to the 'phage' integrase family
H6849_02145	COG0101	tRNA pseudouridine synthase activity
H6849_02150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H6849_02155	COG0242	peptide deformylase activity
H6849_02160	COG1297	OPT oligopeptide transporter protein
H6849_02165	COG1530	ribonuclease E activity
H6849_02170	COG0357	Ribosomal RNA small subunit methyltransferase G
H6849_02180	COG1475	DNA binding
H6849_02185	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H6849_02190	COG1132	(ABC) transporter
H6849_02195	COG2121	Domain of unknown function (DUF374)
H6849_02200	COG1519	Transferase
H6849_02205	COG1663	tetraacyldisaccharide 4'-kinase activity
H6849_02230	COG0629	single-stranded DNA binding
H6849_02235	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H6849_02240	COG2205	protein histidine kinase activity
H6849_02245	COG0772	Belongs to the SEDS family
H6849_02250	COG0768	penicillin binding
H6849_02270	COG4783	chaperone-mediated protein folding
H6849_02280	COG0393	Putative heavy-metal-binding
H6849_02285	COG1450	Type ii and iii secretion system protein
H6849_02290	COG3842	ATPase activity
H6849_02295	COG1176	ABC-type spermidine putrescine transport system, permease component I
H6849_02300	COG1177	transmembrane transport
H6849_02315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H6849_02320	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H6849_02325	COG1420	regulation of RNA biosynthetic process
H6849_02340	COG0438	transferase activity, transferring glycosyl groups
H6849_02355	COG0495	leucyl-tRNA aminoacylation
H6849_02365	COG0750	zinc metalloprotease
H6849_02370	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H6849_02375	COG0616	signal peptide processing
H6849_02380	COG0697	spore germination
H6849_02400	COG3738	Protein conserved in bacteria
H6849_02405	COG0322	excinuclease ABC activity
H6849_02415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H6849_02435	COG2205	protein histidine kinase activity
H6849_02440	COG0745	RESPONSE REGULATOR receiver
H6849_02445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H6849_02450	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H6849_02465	COG0459	protein refolding
H6849_02470	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H6849_02510	COG1278	Cold shock
H6849_02575	COG1757	Na H antiporter
H6849_02600	COG1187	pseudouridine synthase activity
H6849_02605	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H6849_02620	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H6849_02625	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H6849_02630	COG3202	ADP transmembrane transporter activity
H6849_02635	COG0537	adenosine 5'-monophosphoramidase activity
H6849_02640	COG3750	Belongs to the UPF0335 family
H6849_02660	COG0739	heme binding
H6849_02660	COG1388	LysM domain
H6849_02670	COG0805	protein transport
H6849_02675	COG0415	Belongs to the DNA photolyase family
H6849_02685	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
H6849_02730	COG1194	a g-specific adenine glycosylase
H6849_02735	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H6849_02750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H6849_02755	COG0248	Ppx GppA phosphatase
H6849_02760	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
H6849_02765	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H6849_02765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H6849_02780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H6849_02785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H6849_02805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H6849_02820	COG4536	flavin adenine dinucleotide binding
H6849_02835	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H6849_02840	COG0557	exoribonuclease II activity
H6849_02845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H6849_02850	COG0758	DNA mediated transformation
H6849_02855	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H6849_02860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H6849_02905	COG0081	regulation of translation
H6849_02910	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H6849_02915	COG0222	ribosome binding
H6849_02925	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H6849_02930	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H6849_02935	COG0049	tRNA binding
H6849_02950	COG0051	transcription antitermination factor activity, RNA binding
H6849_02955	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H6849_02960	COG0088	Forms part of the polypeptide exit tunnel
H6849_02965	COG0089	rRNA binding
H6849_02975	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H6849_02980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H6849_02990	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H6849_02995	COG0255	Belongs to the universal ribosomal protein uL29 family
H6849_03000	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H6849_03005	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H6849_03010	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H6849_03015	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H6849_03020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H6849_03025	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H6849_03030	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H6849_03035	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H6849_03040	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H6849_03045	COG1841	ribosomal large subunit assembly
H6849_03050	COG0200	Binds to the 23S rRNA
H6849_03060	COG0563	adenylate kinase activity
H6849_03065	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H6849_03070	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H6849_03075	COG0202	RNA polymerase activity
H6849_03085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H6849_03090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H6849_03100	COG0105	UTP biosynthetic process
H6849_03120	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H6849_03125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H6849_03130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H6849_03150	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H6849_03155	COG0356	it plays a direct role in the translocation of protons across the membrane
H6849_03160	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H6849_03165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H6849_03170	COG0552	protein localization to endoplasmic reticulum
H6849_03205	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H6849_03220	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H6849_03230	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H6849_03235	COG0706	membrane insertase activity
H6849_03240	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H6849_03250	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H6849_03255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H6849_03270	COG1074	ATP-dependent DNA helicase activity
H6849_03300	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H6849_03320	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H6849_03325	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H6849_03335	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H6849_03345	COG0519	Catalyzes the synthesis of GMP from XMP
H6849_03350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H6849_03370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H6849_03430	COG0210	DNA helicase
H6849_03435	COG2264	protein methyltransferase activity
H6849_03445	COG1214	PFAM Peptidase M22, glycoprotease
H6849_03475	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H6849_03480	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H6849_03485	COG0181	hydroxymethylbilane synthase activity
H6849_03505	COG0071	Belongs to the small heat shock protein (HSP20) family
H6849_03510	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H6849_03515	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H6849_03520	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H6849_03525	COG0799	negative regulation of ribosome biogenesis
H6849_03550	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
H6849_03565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H6849_03580	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H6849_03585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H6849_03595	COG1692	metallophosphoesterase
H6849_03600	COG1160	GTP binding
H6849_03630	COG0354	folic acid binding
H6849_03635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H6849_03640	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H6849_03645	COG1040	competence protein
H6849_03665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H6849_03675	COG0849	cell division
H6849_03680	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H6849_03685	COG1181	Belongs to the D-alanine--D-alanine ligase family
H6849_03690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H6849_03695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H6849_03700	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H6849_03710	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H6849_03715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H6849_03725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H6849_03730	COG0768	penicillin binding
H6849_03740	COG0275	rRNA processing
H6849_03745	COG2001	Belongs to the MraZ family
H6849_03765	COG2271	Major facilitator Superfamily
H6849_03770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H6849_03770	COG2169	Transcriptional regulator
H6849_03775	COG0367	asparagine synthase
H6849_03790	COG0439	Biotin carboxylase
H6849_03795	COG0511	ligase activity, forming carbon-carbon bonds
H6849_03830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H6849_03840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H6849_03845	COG0564	pseudouridine synthase activity
H6849_03880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H6849_03885	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H6849_03885	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H6849_03890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H6849_03895	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H6849_03900	COG1758	RNA polymerase activity
H6849_03905	COG1686	Belongs to the peptidase S11 family
H6849_03910	COG0359	binds to the 23S rRNA
H6849_03915	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H6849_03925	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H6849_03930	COG3023	N-Acetylmuramoyl-L-alanine amidase
H6849_03940	COG0473	3-isopropylmalate dehydrogenase activity
H6849_03945	COG1923	regulation of RNA biosynthetic process
H6849_03950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H6849_04015	COG1054	Belongs to the UPF0176 family
H6849_04030	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H6849_04040	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H6849_04045	COG5505	Protein of unknown function (DUF819)
H6849_04050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H6849_04060	COG0779	Required for maturation of 30S ribosomal subunits
H6849_04070	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H6849_04095	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H6849_04110	COG0649	NAD binding
H6849_04120	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H6849_04125	COG1034	ATP synthesis coupled electron transport
H6849_04130	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
H6849_04150	COG0539	negative regulation of cytoplasmic translation
H6849_04160	COG0583	DNA-binding transcription factor activity
H6849_04165	COG2009	succinate dehydrogenase
H6849_04175	COG1053	succinate dehydrogenase
H6849_04185	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
H6849_04200	COG5265	(ABC) transporter
H6849_04205	COG1611	Belongs to the LOG family
H6849_04220	COG1132	(ABC) transporter
H6849_04230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H6849_04235	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H6849_04240	COG2089	acid synthase
H6849_04250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H6849_04255	COG1083	cytidylyl-transferase
H6849_04290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H6849_04300	COG0482	sulfurtransferase activity
H6849_04320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H6849_04335	COG0564	pseudouridine synthase activity
H6849_04345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H6849_04360	COG0438	transferase activity, transferring glycosyl groups
H6849_04365	COG0556	nucleotide-excision repair
H6849_04370	COG0583	DNA-binding transcription factor activity
H6849_04410	COG0698	ribose 5-phosphate isomerase
H6849_04420	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
H6849_04440	COG0148	phosphopyruvate hydratase activity
H6849_04445	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H6849_04455	COG0494	nUDIX hydrolase
H6849_04460	COG0793	Belongs to the peptidase S41A family
H6849_04470	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H6849_04475	COG1114	Component of the transport system for branched-chain amino acids
H6849_04480	COG0386	Belongs to the glutathione peroxidase family
H6849_04485	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
H6849_04485	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
H6849_04515	COG0438	transferase activity, transferring glycosyl groups
H6849_04560	COG0756	dUTP diphosphatase activity
H6849_04565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H6849_04565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H6849_04575	COG0358	DNA primase activity
H6849_04580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H6849_04585	COG0328	RNA-DNA hybrid ribonuclease activity
H6849_04595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H6849_04600	COG0416	fatty acid biosynthetic process
H6849_04605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H6849_04610	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H6849_04620	COG1472	Belongs to the glycosyl hydrolase 3 family
H6849_04655	COG0617	tRNA 3'-terminal CCA addition
H6849_04660	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
H6849_04690	COG0717	Belongs to the dCTP deaminase family
H6849_04695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H6849_04700	COG0438	transferase activity, transferring glycosyl groups
H6849_04715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H6849_04740	COG1846	Transcriptional regulator
H6849_04750	COG1329	Transcriptional regulator
H6849_04755	COG0009	L-threonylcarbamoyladenylate synthase
H6849_04765	COG0235	Class ii aldolase
H6849_04785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H6849_04795	COG2226	methyltransferase
H6849_04810	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H6849_04820	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H6849_04825	COG2890	protein-(glutamine-N5) methyltransferase activity
H6849_04830	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H6849_04835	COG0124	histidyl-tRNA synthetase
H6849_04845	COG1183	phosphatidylcholine synthase activity
H6849_04865	COG0400	carboxylic ester hydrolase activity
H6849_04870	COG0039	L-malate dehydrogenase activity
H6849_04885	COG0084	hydrolase, TatD family'
H6849_04890	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H6849_04900	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H6849_04905	COG1686	Belongs to the peptidase S11 family
H6849_04910	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H6849_04920	COG2884	Cell division ATP-binding protein ftsE
H6849_04945	COG0442	prolyl-tRNA aminoacylation
H6849_04955	COG1136	(ABC) transporter
H6849_04960	COG1426	Protein conserved in bacteria
H6849_04965	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H6849_04970	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H6849_05020	COG0590	tRNA wobble adenosine to inosine editing
H6849_05025	COG0114	fumarate hydratase activity
H6849_05035	COG0450	alkyl hydroperoxide reductase
H6849_05040	COG1185	polyribonucleotide nucleotidyltransferase activity
H6849_05045	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H6849_05050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H6849_05055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H6849_05060	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H6849_05065	COG0154	amidase activity
H6849_05070	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H6849_05075	COG2226	methyltransferase
H6849_05080	COG0268	Binds directly to 16S ribosomal RNA
H6849_05090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H6849_05100	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H6849_05140	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H6849_05155	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant