locus-tag	class	description
D5400_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
D5400_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
D5400_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
D5400_00030	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
D5400_00035	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
D5400_00060	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
D5400_00070	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
D5400_00080	ENOG4105CAU	Arsenical resistance protein, ArsH
D5400_00110	ENOG4105BZU	Histidine kinase
D5400_00115	ENOG41083MR	nifu domain-containing protein
D5400_00125	ENOG4105C31	Tryptophanyl-tRNA synthetase
D5400_00135	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
D5400_00140	ENOG4105DU0	nucleoside hydrolase
D5400_00145	ENOG4108ZNX	Heat shock protein
D5400_00155	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
D5400_00160	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
D5400_00170	ENOG4108IUZ	ABC transporter
D5400_00175	ENOG4105RF0	OstA family
D5400_00190	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D5400_00200	ENOG4105CIF	Ornithine Cyclodeaminase
D5400_00220	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
D5400_00225	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
D5400_00240	ENOG41090R7	Ferric uptake
D5400_00245	ENOG4108Z20	Acyl-transferase
D5400_00250	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
D5400_00255	ENOG4105C9A	Phoh family
D5400_00260	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
D5400_00265	ENOG4108JU5	Magnesium and cobalt efflux protein
D5400_00270	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
D5400_00275	ENOG4108WRK	Transcriptional regulator
D5400_00280	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
D5400_00285	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
D5400_00290	ENOG4105CHC	glucokinase (EC 2.7.1.2)
D5400_00295	ENOG4108Z5K	methylglyoxal synthase
D5400_00300	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
D5400_00310	ENOG410838F	Glycosyl transferase family 2
D5400_00335	ENOG4105CSM	endonuclease III
D5400_00340	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
D5400_00345	ENOG4105C6K	Malic enzyme
D5400_00350	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D5400_00355	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D5400_00360	ENOG4105EN6	Membrane
D5400_00370	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
D5400_00375	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
D5400_00380	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
D5400_00390	ENOG4108RVA	ribokinase
D5400_00395	ENOG4105CPF	Cell wall formation (By similarity)
D5400_00405	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
D5400_00410	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
D5400_00420	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
D5400_00425	ENOG4105CSA	Coproporphyrinogen iii oxidase
D5400_00430	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
D5400_00435	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
D5400_00440	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
D5400_00510	ENOG4107SZR	mannose-6-phosphate isomerase
D5400_00515	ENOG41090KN	UPF0303 protein
D5400_00520	ENOG4105DKQ	ROK family
D5400_00525	ENOG4108IJ9	(ABC) transporter
D5400_00530	ENOG4105DRS	transport system, permease
D5400_00535	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
D5400_00540	ENOG4108JP0	extracellular solute-binding protein family 1
D5400_00545	ENOG4105FKQ	transcriptional regulator
D5400_00555	ENOG4105CFU	surface antigen
D5400_00580	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D5400_00595	ENOG4107QP3	malate synthase g
D5400_00605	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
D5400_00615	ENOG4108UYB	regulatoR
D5400_00620	ENOG4105TX3	Histidine kinase
D5400_00625	ENOG4105CQ7	ATP-dependent helicase
D5400_00630	ENOG4108VGW	abc transporter atp-binding protein
D5400_00635	ENOG4105CXZ	ABC transporter, permease
D5400_00640	ENOG4105VNH	ABC transporter solute-binding protein
D5400_00645	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
D5400_00650	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
D5400_00655	ENOG4105KK3	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
D5400_00675	ENOG4105BZU	Histidine kinase
D5400_00745	ENOG4108UUM	single-stranded DNA-binding protein
D5400_00755	ENOG4108VSE	mercuric transport protein
D5400_00845	ENOG4105E4C	Lytic transglycosylase catalytic
D5400_00865	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
D5400_00875	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
D5400_00880	ENOG4107QIV	Cytochrome c biogenesis protein
D5400_00890	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
D5400_00905	ENOG4105H3G	oxidoreductase
D5400_00910	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
D5400_00915	ENOG41085KW	ppic-type peptidyL-prolyl cis-trans isomerase
D5400_00925	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
D5400_00935	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
D5400_00970	ENOG4105C59	p-type ATPase
D5400_00980	ENOG4108ZX6	Electron transport protein SCO1 SenC
D5400_00995	ENOG4105PGM	cation diffusion facilitator family transporter
D5400_01010	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D5400_01020	ENOG4105W1Y	Transcriptional regulator
D5400_01030	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
D5400_01040	ENOG4105E4C	Lytic transglycosylase catalytic
D5400_01055	ENOG4105DA4	cytochrome c-type biogenesis protein
D5400_01060	ENOG4107ZT5	Thiol disulfide interchange protein
D5400_01070	ENOG4108KSA	LysR family transcriptional regulator
D5400_01175	ENOG4105DUM	transcriptional regulator, lysR family
D5400_01180	ENOG4105HMI	Membrane
D5400_01185	ENOG4105E0X	reductase
D5400_01200	ENOG4105CAS	nag kinase
D5400_01220	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
D5400_01230	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
D5400_01235	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
D5400_01255	ENOG4108JQC	penicillin-binding protein 1A
D5400_01260	ENOG4105CFG	Acts as a chaperone (By similarity)
D5400_01265	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D5400_01280	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
D5400_01295	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
D5400_01305	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
D5400_01315	ENOG4105K6T	rare lipoprotein A
D5400_01320	ENOG4105UT3	Methyl-accepting chemotaxis
D5400_01325	ENOG4108JQ6	ABC transporter
D5400_01330	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D5400_01340	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
D5400_01345	ENOG4107S4Y	M20 DapE family protein YgeY
D5400_01360	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
D5400_01365	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
D5400_01370	ENOG4107QMP	dna polymerase iii subunits gamma and tau
D5400_01385	ENOG4105E09	nadh pyrophosphatase
D5400_01395	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
D5400_01400	ENOG4105G9V	cytochrome C
D5400_01415	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
D5400_01420	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
D5400_01435	ENOG4108JQ5	ABC transporter
D5400_01440	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
D5400_01445	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
D5400_01465	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D5400_01475	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
D5400_01485	ENOG4105ECK	Fatty Acid Desaturase
D5400_01500	ENOG4105DRP	amino acid AbC transporter
D5400_01505	ENOG4105EAB	amino acid AbC transporter
D5400_01510	ENOG4105DRR	Transcriptional regulator, GntR family
D5400_01515	ENOG4105CHR	reductase
D5400_01525	ENOG4105CHM	Aminotransferase
D5400_01540	ENOG4105DFI	Membrane
D5400_01545	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
D5400_01550	ENOG4105C2M	dna polymerase I
D5400_01600	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
D5400_01605	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
D5400_01610	ENOG410903D	sensor protein
D5400_01615	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
D5400_01620	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
D5400_01625	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
D5400_01640	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
D5400_01650	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
D5400_01655	ENOG4105ZDB	Protein slyX homolog
D5400_01665	ENOG4108JQ9	ABC transporter
D5400_01690	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
D5400_01695	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
D5400_01705	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
D5400_01715	ENOG4105C26	Dehydrogenase
D5400_01720	ENOG4105C5F	glutamine synthetase
D5400_01730	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_01750	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
D5400_01755	ENOG41082FP	UPF0102 protein
D5400_01760	ENOG4105D7Z	glutathione synthase
D5400_01765	ENOG4105C0P	Mg chelatase subunit ChlI
D5400_01775	ENOG4105MIR	Phenylalanine 4-monooxygenase
D5400_01780	ENOG4105EW9	transcriptional regulator AsnC family
D5400_01785	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
D5400_01790	ENOG4105C4M	(Ubiquinol oxidase) subunit I
D5400_01830	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D5400_01835	ENOG41082BR	50S ribosomal protein L35
D5400_01840	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
D5400_01850	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
D5400_01870	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
D5400_01875	ENOG4107SDU	Methyl-accepting chemotaxis
D5400_01880	ENOG4105DIH	basic membrane
D5400_01885	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D5400_01905	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D5400_01915	ENOG4106IPI	cyclase, family
D5400_01935	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D5400_01950	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
D5400_01955	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
D5400_01960	ENOG4105WH1	Two component transcriptional regulator luxr family
D5400_01965	ENOG4105NNS	Autoinducer synthesis protein
D5400_01980	ENOG4108UT2	hemolysin iii
D5400_01985	ENOG4107EJG	GntR family transcriptional regulator
D5400_01995	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D5400_02005	ENOG4105CHR	reductase
D5400_02040	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
D5400_02045	ENOG4105CXK	mandelate racemase muconate lactonizing
D5400_02070	ENOG4105CHR	reductase
D5400_02075	ENOG4108KK1	membrane protein AbrB duplication
D5400_02080	ENOG4105CMJ	mandelate racemase muconate lactonizing
D5400_02105	ENOG4108M9J	MaoC like domain protein
D5400_02115	ENOG4105C1G	acyl-Coa dehydrogenase
D5400_02120	ENOG4108PGP	mmge prpd family protein
D5400_02130	ENOG4107U9H	DNA polymerase
D5400_02140	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
D5400_02145	ENOG4105CAT	Cytidine monophosphate kinase
D5400_02150	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
D5400_02170	ENOG4105CHR	reductase
D5400_02175	ENOG4105C6F	GntR Family Transcriptional Regulator
D5400_02185	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
D5400_02190	ENOG4108IY8	ABC, transporter
D5400_02195	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
D5400_02210	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
D5400_02215	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D5400_02225	ENOG4108UQ8	endoribonuclease L-psp
D5400_02255	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_02260	ENOG4108K1J	Transporter DctQ
D5400_02265	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
D5400_02270	ENOG4107SZR	mannose-6-phosphate isomerase
D5400_02275	ENOG4107XBN	GntR Family Transcriptional Regulator
D5400_02280	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
D5400_02285	ENOG4105DEI	Mannitol dehydrogenase
D5400_02290	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
D5400_02305	ENOG410830R	acetyltransferase
D5400_02310	ENOG4105EUB	pirin domain protein
D5400_02315	ENOG4105JQN	Transcriptional regulator
D5400_02335	ENOG4108IJ9	(ABC) transporter
D5400_02360	ENOG4105D38	putrescine abc transporter
D5400_02365	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D5400_02370	ENOG410642W	LysR family Transcriptional regulator
D5400_02375	ENOG4105E1F	short-chain dehydrogenase reductase
D5400_02405	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
D5400_02410	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
D5400_02415	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
D5400_02420	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
D5400_02425	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
D5400_02435	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
D5400_02445	ENOG4108S0S	Nucleotidyl transferase
D5400_02450	ENOG4105EHM	Aminoglycoside phosphotransferase
D5400_02455	ENOG4105I8F	Histidine kinase
D5400_02460	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
D5400_02470	ENOG4108EQA	pts system
D5400_02480	ENOG4105EB3	Histidine kinase
D5400_02485	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D5400_02490	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
D5400_02495	ENOG4108YZN	class I peptide chain release factor
D5400_02500	ENOG4105CF1	Alkylated DNA repair protein
D5400_02510	ENOG4105CS9	pantothenic acid kinase
D5400_02515	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
D5400_02520	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
D5400_02525	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
D5400_02530	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
D5400_02540	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
D5400_02545	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
D5400_02550	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
D5400_02580	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
D5400_02585	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
D5400_02590	ENOG4107RZZ	dna polymerase iii epsilon subunit
D5400_02595	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
D5400_02600	ENOG4105E2X	shikimate dehydrogenase
D5400_02605	ENOG4108UHJ	MAF-like protein
D5400_02610	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
D5400_02615	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
D5400_02620	ENOG4108YXA	Membrane
D5400_02625	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
D5400_02630	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
D5400_02635	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
D5400_02640	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
D5400_02645	ENOG4107QJE	Chromosome Partitioning Protein
D5400_02650	ENOG4105FA0	parb-like partition protein
D5400_02665	ENOG4105C8T	Leucyl-tRNA synthetase
D5400_02670	ENOG4105DFA	alanine racemase domain protein
D5400_02690	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
D5400_02695	ENOG4105D0M	Protease HtpX homolog
D5400_02715	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D5400_02725	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
D5400_02730	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D5400_02735	ENOG4105C7I	Dehydrogenase
D5400_02755	ENOG4107B2H	carbonic anhydrase
D5400_02765	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
D5400_02770	ENOG4105T0Z	Conserved Protein
D5400_02775	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D5400_02785	ENOG4108YZA	Nitrogen regulatory protein pii
D5400_02790	ENOG4105C29	acyl-CoA thioesterase
D5400_02800	ENOG4105W49	UPF0434 protein
D5400_02805	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
D5400_02810	ENOG4105K63	Thioredoxin
D5400_02825	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D5400_02830	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
D5400_02835	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
D5400_02875	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D5400_02885	ENOG4105CNU	cell division protein FtsK
D5400_02890	ENOG4107TMZ	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
D5400_02900	ENOG4108TPP	exopolysaccharide synthesis
D5400_02915	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D5400_02925	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
D5400_02940	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
D5400_02945	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D5400_02950	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
D5400_02975	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
D5400_02985	ENOG4105F0N	pyrophosphate phospho-hydrolase
D5400_02990	ENOG4108Z7F	N-acetyltransferase
D5400_03000	ENOG4105DGW	oligopeptidase A
D5400_03010	ENOG4105CNH	Multidrug resistance protein MdtL
D5400_03015	ENOG4105CDH	Citrulline--aspartate ligase
D5400_03030	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
D5400_03040	ENOG4105K6V	RNA polymerase
D5400_03050	ENOG4105KZX	Pterin carbinolamine dehydratase
D5400_03055	ENOG4105M7V	2'-5' rna ligase
D5400_03065	ENOG4108I0Y	(ABC) transporter
D5400_03070	ENOG4105CV6	ABC transporter, permease
D5400_03075	ENOG4105HFZ	Membrane
D5400_03095	ENOG4107QM5	aconitate hydratase
D5400_03100	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
D5400_03105	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
D5400_03110	ENOG41060IM	Heme exporter protein
D5400_03120	ENOG4107QX9	Thiol disulfide interChange protein
D5400_03130	ENOG4105X54	addiction module antidote protein
D5400_03135	ENOG4107835	probably involved in intracellular septation (By similarity)
D5400_03140	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
D5400_03145	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
D5400_03150	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
D5400_03165	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D5400_03170	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
D5400_03175	ENOG4105K5M	30s ribosomal protein S16
D5400_03180	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
D5400_03185	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
D5400_03190	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
D5400_03195	ENOG4106PMH	Extracellular solute-binding protein family 3
D5400_03200	ENOG4105E5Q	amino acid AbC transporter
D5400_03205	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D5400_03210	ENOG4106TD9	Diguanylate cyclase
D5400_03230	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
D5400_03240	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
D5400_03245	ENOG4105E33	succinate dehydrogenase
D5400_03255	ENOG4108Z9K	Osmotically inducible protein
D5400_03260	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D5400_03265	ENOG4105YU5	Outer membrane lipoprotein
D5400_03270	ENOG4105D6Z	AFG1 family ATPase
D5400_03275	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
D5400_03280	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
D5400_03290	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
D5400_03295	ENOG4105C7S	Dehydrogenase
D5400_03300	ENOG4107QN2	dihydrolipoyl dehydrogenase
D5400_03320	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D5400_03335	ENOG4105DHQ	Histidine kinase
D5400_03355	ENOG4107R0V	Pyruvate dehydrogenase
D5400_03360	ENOG4105CPP	Dehydrogenase, E1 component
D5400_03365	ENOG4107QSN	dihydrolipoamide acetyltransferase
D5400_03370	ENOG4107QN2	dihydrolipoyl dehydrogenase
D5400_03375	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
D5400_03380	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
D5400_03385	ENOG4105C25	Primosomal protein n'
D5400_03395	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D5400_03400	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
D5400_03405	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
D5400_03410	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
D5400_03415	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
D5400_03430	ENOG4105CN1	protease
D5400_03445	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
D5400_03450	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D5400_03455	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
D5400_03460	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
D5400_03465	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
D5400_03485	ENOG4105K46	50S ribosomal protein l27
D5400_03490	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
D5400_03530	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
D5400_03540	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_03555	ENOG4106517	Short-chain dehydrogenase reductase Sdr
D5400_03565	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
D5400_03575	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
D5400_03585	ENOG4108V3W	Chemotaxis protein, CheW
D5400_03600	ENOG4107PP3	Acetylornithine deacetylase
D5400_03605	ENOG4108JQ7	(ABC) transporter
D5400_03615	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D5400_03620	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
D5400_03625	ENOG4105CWC	Acetylornithine deacetylase
D5400_03640	ENOG4105CHM	Aminotransferase
D5400_03695	ENOG4107BVJ	4,5-dihydroxyphthalate decarboxylase
D5400_03705	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_03715	ENOG4108S8N	class II Aldolase
D5400_03720	ENOG4105EJC	lysr family transcriptional regulator
D5400_03725	ENOG4105C7K	acetolactate synthase
D5400_03735	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_03760	ENOG4105CHR	reductase
D5400_03770	ENOG4107RUY	(E1 component), alpha subunit
D5400_03775	ENOG4105CPP	Dehydrogenase, E1 component
D5400_03780	ENOG4107R0V	Pyruvate dehydrogenase
D5400_03830	ENOG4105QPS	Monooxygenase
D5400_03855	ENOG4105CG5	Glycosyl transferase (Group 1
D5400_03865	ENOG41082I2	s4 domain protein
D5400_03880	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
D5400_03890	ENOG4105EXG	Transcriptional regulator
D5400_03895	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
D5400_03905	ENOG4107U9T	Pfam:Ribonuclease_BN
D5400_03910	ENOG410870F	Cyclic nucleotide-binding protein
D5400_03915	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D5400_03965	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
D5400_03970	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
D5400_03980	ENOG4105C0Z	ABC transporter
D5400_03985	ENOG4108IV0	ABC, transporter
D5400_03995	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
D5400_04000	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
D5400_04045	ENOG4105DZG	Dehydrogenase
D5400_04050	ENOG4108U4V	Cytochrome c protein
D5400_04055	ENOG4108Q1J	Extracellular solute-binding protein, family 3
D5400_04075	ENOG4105CJ1	ABC, transporter
D5400_04085	ENOG4105C4W	S-formylglutathione hydrolase
D5400_04090	ENOG4107QPD	alcohol dehydrogenase
D5400_04125	ENOG4105BZU	Histidine kinase
D5400_04135	ENOG4105C94	Transporter
D5400_04140	ENOG4105C5Q	Transcriptional regulator
D5400_04160	ENOG4105DZG	Dehydrogenase
D5400_04180	ENOG4105F04	LysR family Transcriptional regulator
D5400_04200	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D5400_04205	ENOG4107EFR	Flavocytochrome c
D5400_04240	ENOG4105DG4	malate L-lactate dehydrogenase
D5400_04250	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
D5400_04270	ENOG4105CBX	hi0933 family
D5400_04275	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
D5400_04280	ENOG4107URF	beta-phospho-glucomutase
D5400_04285	ENOG4105DEI	Mannitol dehydrogenase
D5400_04290	ENOG4105CHR	reductase
D5400_04295	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D5400_04325	ENOG4105DKT	Transcriptional regulator
D5400_04335	ENOG4105D5T	phosphonate abc transporter
D5400_04340	ENOG4105S7S	phosphonate abc transporter
D5400_04350	ENOG4105FDP	GntR family transcriptional regulator
D5400_04360	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
D5400_04385	ENOG4105CHR	reductase
D5400_04390	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
D5400_04400	ENOG4105C1G	acyl-Coa dehydrogenase
D5400_04405	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
D5400_04415	ENOG4105C59	p-type ATPase
D5400_04425	ENOG4105VP2	Transcriptional regulator, Crp Fnr family
D5400_04440	ENOG4108ZJ4	polysaccharide deacetylase
D5400_04470	ENOG4108VX5	3-methyladenine DNA glycosylase
D5400_04530	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
D5400_04535	ENOG4107TTD	cytosine deaminase
D5400_04545	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
D5400_04555	ENOG4105C5H	ABC transporter
D5400_04575	ENOG4107T0D	ABC, transporter
D5400_04585	ENOG4108Z4U	Ferredoxin
D5400_04590	ENOG4108VJ1	Transcriptional regulator (CarD family
D5400_04595	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D5400_04610	ENOG4105C26	Dehydrogenase
D5400_04630	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
D5400_04635	ENOG4105BZU	Histidine kinase
D5400_04640	ENOG4105CTB	Polyprenyl synthetase
D5400_04645	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
D5400_04650	ENOG4108TGY	Glutathione S-transferase
D5400_04690	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_04700	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
D5400_04705	ENOG4106UW1	Major Facilitator superfamily
D5400_04710	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
D5400_04720	ENOG4107R7Y	intracellular protease Pfpi family
D5400_04760	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
D5400_04780	ENOG4105E2V	Glycosyltransferase 36
D5400_04790	ENOG4105J6N	PhotosynthetiC reaction center cytochrome c subunit
D5400_04825	ENOG41060GA	Chlorophyllide reductase subunit Y
D5400_04830	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
D5400_04835	ENOG4107XHQ	chlorophyll synthesis pathway, bchC
D5400_04840	ENOG4107EPK	O-methyltransferase, family 2
D5400_04845	ENOG4105CTB	Polyprenyl synthetase
D5400_04865	ENOG4105FE1	phytoene synthase
D5400_04870	ENOG4105EWK	phytoene
D5400_04880	ENOG4107SV1	subunit D
D5400_04890	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
D5400_04910	ENOG4105CH2	amidohydrolase
D5400_04915	ENOG4105DZ1	carboxypeptidase
D5400_04920	ENOG4105CKI	cobalamin synthesis protein
D5400_04930	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
D5400_04935	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
D5400_04940	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D5400_04965	ENOG4105BZU	Histidine kinase
D5400_04975	ENOG4105BZ1	(ABC) transporter
D5400_04985	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D5400_04990	ENOG4108TF2	Photosynthetic complex assembly protein 2
D5400_04995	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
D5400_05020	ENOG4105XCI	PucC protein
D5400_05025	ENOG4108MIC	Mg-protoporphyrin IX methyl transferase
D5400_05030	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
D5400_05035	ENOG4105CTK	cobaltochelatase, cobn subunit
D5400_05040	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
D5400_05045	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
D5400_05050	ENOG4108VJI	2-vinyl bacteriochlorophyllide hydratase
D5400_05060	ENOG4105D4D	transcriptional regulator
D5400_05065	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
D5400_05070	ENOG4105SS7	PucC protein
D5400_05075	ENOG4107QZT	geranylgeranyl reductase
D5400_05085	ENOG4105KAV	tspo and mbr like protein
D5400_05100	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
D5400_05105	ENOG4108JPW	Aminotransferase
D5400_05110	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
D5400_05115	ENOG4105CZK	Aspartate kinase
D5400_05120	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
D5400_05125	ENOG4105C2J	ABC transporter
D5400_05130	ENOG4105CNN	ABC, transporter
D5400_05135	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
D5400_05145	ENOG4105C8Y	Acetylornithine aminotransferase
D5400_05160	ENOG4105ENR	peptidase, M24
D5400_05180	ENOG4105DTD	Dehydrogenase
D5400_05185	ENOG4105EKE	dihydroorotase
D5400_05190	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
D5400_05210	ENOG4107QP8	phosphohexose isomerase
D5400_05225	ENOG4105CEY	Amp-dependent synthetase and ligase
D5400_05235	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
D5400_05240	ENOG4105C0B	DNA polymerase III (alpha subunit)
D5400_05280	ENOG4105CSR	polyphosphate kinase 2
D5400_05285	ENOG4105BZU	Histidine kinase
D5400_05295	ENOG4105C8U	phosphate abc transporter
D5400_05305	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
D5400_05310	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
D5400_05315	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D5400_05325	ENOG4105C8Y	Acetylornithine aminotransferase
D5400_05330	ENOG4105DBV	ornithine carbamoyltransferase
D5400_05335	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
D5400_05345	ENOG4105BZS	acriflavin resistance protein
D5400_05350	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
D5400_05355	ENOG4105NWN	ApaG protein
D5400_05370	ENOG4105DHP	deoxycytidine triphosphate deaminase
D5400_05405	ENOG4105DK7	lysyl-tRNA synthetase
D5400_05415	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
D5400_05430	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D5400_05435	ENOG4105CHU	acetyl-coa acetyltransferase
D5400_05440	ENOG4105C1G	acyl-Coa dehydrogenase
D5400_05445	ENOG4105CSU	acyl-Coa dehydrogenase
D5400_05475	ENOG4107QRT	dEAD DEAH box helicase
D5400_05480	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
D5400_05495	ENOG4107T0X	DNA ligase
D5400_05515	ENOG4105DGU	Histone deacetylase
D5400_05520	ENOG4107R73	Mate efflux family protein
D5400_05525	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
D5400_05555	ENOG4105BZU	Histidine kinase
D5400_05560	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
D5400_05580	ENOG4105KHC	sulfurtransferase
D5400_05585	ENOG41066VF	YeeE YedE family protein
D5400_05600	ENOG4107W75	Flagellin
D5400_05620	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
D5400_05630	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
D5400_05635	ENOG4108ZTZ	UPF0262 protein
D5400_05645	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
D5400_05650	ENOG4108Z03	MAF-like protein
D5400_05670	ENOG4105EW9	transcriptional regulator AsnC family
D5400_05685	ENOG4105UT3	Methyl-accepting chemotaxis
D5400_05695	ENOG4108VYJ	response regulator receiver protein
D5400_05700	ENOG4105CBS	Chea signal transduction histidine kinase
D5400_05705	ENOG4108V3W	Chemotaxis protein, CheW
D5400_05710	ENOG4105BZU	Histidine kinase
D5400_05715	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D5400_05720	ENOG4108VYJ	response regulator receiver protein
D5400_05725	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
D5400_05735	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
D5400_05755	ENOG4105QDQ	
D5400_05760	ENOG4105D00	flagellar biosynthetic protein flhB
D5400_05765	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
D5400_05770	ENOG4105DD5	Flagellar motor switch protein
D5400_05780	ENOG4107RD7	Flagellar Motor Protein, MotA
D5400_05790	ENOG4105KTQ	flagellar basal-body rod protein
D5400_05795	ENOG4108JIR	Flagellum-specific ATP synthase
D5400_05805	ENOG4105SFI	flagellar basal-body rod protein
D5400_05810	ENOG4108ZC9	flagellar basal-body rod protein flgc
D5400_05815	ENOG4105X50	flagellar hook-basal body complex protein fliE
D5400_05820	ENOG4105CGA	flagellar basal-body rod protein FlgG
D5400_05825	ENOG4105XZC	flagellar basal body P-ring biosynthesis protein FlgA
D5400_05830	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D5400_05840	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D5400_05850	ENOG4105CN7	Flagellar biosynthetic protein FliP
D5400_05855	ENOG4107W75	Flagellin
D5400_05860	ENOG4107W75	Flagellin
D5400_05870	ENOG4105D2T	synthase
D5400_05885	ENOG4105F0R	Cytidylyltransferase
D5400_05890	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D5400_05895	ENOG4105C5E	polysaccharide biosynthesis protein
D5400_05905	ENOG4105ER2	Ompa motb domain protein
D5400_05910	ENOG4108S15	chemotaxis, protein
D5400_05930	ENOG4105BZE	flagellar hook protein, FlgE
D5400_05950	ENOG4105KHD	Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK mRNA and promotes its degradation (By similarity)
D5400_05955	ENOG410822I	Flagellar hook capping protein
D5400_05965	ENOG4105D7B	Flagellar biosynthesis protein flha
D5400_05970	ENOG4108TN6	type iii secretion
D5400_05995	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
D5400_06000	ENOG4105FKQ	transcriptional regulator
D5400_06010	ENOG4105EPJ	extracellular solute-binding protein family 1
D5400_06015	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
D5400_06020	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
D5400_06025	ENOG4105CG3	alpha amylase, catalytic region
D5400_06030	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D5400_06035	ENOG4105C01	Dihydroxy-acid dehydratase
D5400_06040	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
D5400_06045	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
D5400_06050	ENOG4105CJP	fad dependent oxidoreductase
D5400_06055	ENOG4105CFQ	glutamine synthetase
D5400_06075	ENOG410841Q	phosphoesterase PA-phosphatase related protein
D5400_06100	ENOG4105CFF	transcriptional regulator
D5400_06110	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D5400_06115	ENOG4105F38	ABC transporter, permease
D5400_06120	ENOG4105D38	putrescine abc transporter
D5400_06130	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D5400_06135	ENOG4105BZU	Histidine kinase
D5400_06215	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
D5400_06220	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
D5400_06250	ENOG4105D65	subunit l
D5400_06255	ENOG4105GND	monovalent cation H antiporter subunit B
D5400_06260	ENOG4105MKQ	Monovalent cation H antiporter subunit C
D5400_06265	ENOG4108JPZ	Monovalent cation H antiporter subunit D
D5400_06280	ENOG4105KJM	monovalent cation h antiporter subunit g
D5400_06285	ENOG4105BZU	Histidine kinase
D5400_06290	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D5400_06300	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
D5400_06305	ENOG4108JQ5	ABC transporter
D5400_06310	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D5400_06315	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
D5400_06320	ENOG4107QSI	ABC, transporter
D5400_06330	ENOG4107QN1	sodium solute
D5400_06345	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
D5400_06350	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D5400_06360	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
D5400_06365	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
D5400_06370	ENOG4105C3Q	Glycosyl transferase, family 2
D5400_06375	ENOG4107QW3	Sucrose phosphorylase
D5400_06405	ENOG41080HT	Transcriptional regulator, arsr family
D5400_06410	ENOG4107QPB	Beta-lactamase domain protein
D5400_06420	ENOG4108IV0	ABC, transporter
D5400_06425	ENOG4105C0Z	ABC transporter
D5400_06435	ENOG4105C32	Amino acid ABC transporter (Permease)
D5400_06445	ENOG4108ES0	acetoacetyl-CoA synthetase
D5400_06485	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
D5400_06490	ENOG4108UKI	Enoyl-CoA hydratase
D5400_06495	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D5400_06510	ENOG4105CYM	Glutathione S-transferase
D5400_06540	ENOG4105G4C	Periplasmic ligand-binding sensor protein
D5400_06555	ENOG4105TAV	cytochrome C
D5400_06560	ENOG4108S01	response regulator
D5400_06565	ENOG4105BZU	Histidine kinase
D5400_06600	ENOG4105D7Q	type ii secretion system
D5400_06605	ENOG4108VAU	general secretion pathway protein G
D5400_06645	ENOG4107QHF	type ii secretion system protein e
D5400_06650	ENOG4105GVR	general secretion pathway protein D
D5400_06660	ENOG4105BZU	Histidine kinase
D5400_06665	ENOG4105WH1	Two component transcriptional regulator luxr family
D5400_06675	ENOG4107VRP	DNA repair exonuclease
D5400_06680	ENOG4106D4I	domain protein
D5400_06685	ENOG4105RAK	Histidine kinase
D5400_06690	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
D5400_06705	ENOG4108DEF	Globin
D5400_06715	ENOG4105BZ9	Cytochrome C oxidase, subunit I
D5400_06720	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
D5400_06745	ENOG4105XEA	Tetr family transcriptional regulator
D5400_06760	ENOG4108RMU	ferritin dps family protein
D5400_06765	ENOG4105CH5	extracellular solute-binding protein, family 7
D5400_06775	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_06780	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D5400_06785	ENOG4105DRR	Transcriptional regulator, GntR family
D5400_06795	ENOG4105RQF	LysR family Transcriptional regulator
D5400_06805	ENOG4108XM1	transcriptional regulator AsnC family
D5400_06815	ENOG4105CFF	transcriptional regulator
D5400_06820	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D5400_06825	ENOG4105CPQ	Dehydrogenase
D5400_06830	ENOG4105E1J	oxidoreductase
D5400_06850	ENOG4107RUE	extracellular solute-binding protein family 1
D5400_06855	ENOG4105F38	ABC transporter, permease
D5400_06860	ENOG4105D38	putrescine abc transporter
D5400_06865	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D5400_06875	ENOG4105CUC	YeeE YedE family protein
D5400_06895	ENOG4107S7U	Sulfide dehydrogenase
D5400_06915	ENOG4105F38	ABC transporter, permease
D5400_06920	ENOG4105D38	putrescine abc transporter
D5400_06925	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D5400_06940	ENOG4105CYW	agmatinase
D5400_06955	ENOG4108MEK	Metal-binding protein YodA
D5400_06965	ENOG4105HDK	L-asparaginase
D5400_06970	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
D5400_06995	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
D5400_07000	ENOG4105E2X	shikimate dehydrogenase
D5400_07005	ENOG4108PVQ	transcriptional regulator
D5400_07010	ENOG4108PVQ	transcriptional regulator
D5400_07015	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
D5400_07025	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_07030	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
D5400_07050	ENOG4107RNG	ABC transporter
D5400_07060	ENOG4105DFW	ABC transporter
D5400_07065	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
D5400_07070	ENOG41062B0	ABC transporter, permease
D5400_07075	ENOG4107R9N	ABC transporter
D5400_07080	ENOG4105C2J	ABC transporter
D5400_07085	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
D5400_07095	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
D5400_07135	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
D5400_07140	ENOG4105HRV	phosphonate c-p lyase system protein phnl
D5400_07150	ENOG4106ZX3	phosphonate ABC transporter, periplasmic phosphonate-binding protein
D5400_07155	ENOG4105D5T	phosphonate abc transporter
D5400_07175	ENOG4108T58	Mg2 transport protein CorA
D5400_07190	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
D5400_07195	ENOG4105BZU	Histidine kinase
D5400_07205	ENOG4105C5H	ABC transporter
D5400_07225	ENOG4105SCY	DNAK suppressor
D5400_07260	ENOG4105BZU	Histidine kinase
D5400_07265	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D5400_07270	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
D5400_07285	ENOG4105D7T	ABC transporter
D5400_07305	ENOG4108IND	Tetr family transcriptional regulator
D5400_07310	ENOG4105CPC	Aldo Keto reductase
D5400_07345	ENOG4105E98	transcriptional regulator DeoR family
D5400_07350	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
D5400_07355	ENOG4108IJ9	(ABC) transporter
D5400_07360	ENOG4108IJ9	(ABC) transporter
D5400_07365	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
D5400_07370	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
D5400_07385	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
D5400_07395	ENOG4105BZU	Histidine kinase
D5400_07405	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
D5400_07410	ENOG4105KPV	Transcriptional regulator
D5400_07415	ENOG41080HT	Transcriptional regulator, arsr family
D5400_07425	ENOG4107104	thymidine kinase
D5400_07430	ENOG4105G9V	cytochrome C
D5400_07440	ENOG4105EW9	transcriptional regulator AsnC family
D5400_07445	ENOG4105C26	Dehydrogenase
D5400_07450	ENOG4105CKU	formyltetrahydrofolate synthetase
D5400_07465	ENOG4105CRQ	synthase (Component I)
D5400_07475	ENOG4105FDT	acyl-CoA dehydrogenase
D5400_07480	ENOG4105KVH	Transcriptional regulator
D5400_07490	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
D5400_07495	ENOG4108JJB	ABC transporter
D5400_07535	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
D5400_07540	ENOG4107TTQ	Alpha beta hydrolase fold
D5400_07560	ENOG4105CHF	Glutathione S-transferase
D5400_07585	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D5400_07595	ENOG4105P8F	nudix hydrolase
D5400_07600	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
D5400_07610	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
D5400_07620	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
D5400_07625	ENOG4105BZ1	(ABC) transporter
D5400_07630	ENOG4105BZ1	(ABC) transporter
D5400_07635	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
D5400_07645	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
D5400_07650	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
D5400_07665	ENOG4105C3G	gtp-binding protein
D5400_07670	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
D5400_07675	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
D5400_07685	ENOG4105C01	Dihydroxy-acid dehydratase
D5400_07690	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
D5400_07705	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
D5400_07715	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
D5400_07730	ENOG4105II7	pyrroline-5-carboxylate reductase
D5400_07735	ENOG4108Z7R	Chaperone CsaA
D5400_07740	ENOG4105BZU	Histidine kinase
D5400_07745	ENOG4105E0F	Histidine kinase
D5400_07750	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D5400_07755	ENOG41090HR	transcriptional regulator
D5400_07760	ENOG4105CM2	brancheD-chain amino acid aminotransferase
D5400_07770	ENOG4105C5X	domain protein
D5400_07780	ENOG4105VEQ	Cold shock protein
D5400_07800	ENOG4105EPM	Diguanylate phosphodiesterase
D5400_07805	ENOG4105CHM	Aminotransferase
D5400_07810	ENOG4105CBN	LysR family transcriptional regulator
D5400_07815	ENOG4105C3M	thioredoxin reductase
D5400_07820	ENOG4105F7P	transcriptional regulator AsnC family
D5400_07825	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
D5400_07830	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
D5400_07840	ENOG4105CGZ	zinc metallopeptidase
D5400_07850	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
D5400_07870	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D5400_07875	ENOG4108Q5F	Tetr family transcriptional regulator
D5400_07885	ENOG4105BZU	Histidine kinase
D5400_07910	ENOG4105MPN	Membrane
D5400_07925	ENOG4105CF7	AraC family transcriptional regulator
D5400_07930	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
D5400_07945	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5400_07950	ENOG4105BZU	Histidine kinase
D5400_07960	ENOG4105CHR	reductase
D5400_07965	ENOG4106IPI	cyclase, family
D5400_07970	ENOG4105E1F	short-chain dehydrogenase reductase
D5400_07980	ENOG4105CEY	Amp-dependent synthetase and ligase
D5400_07985	ENOG4108UKV	benzoate 1,2-dioxygenase
D5400_07990	ENOG4105FUY	alpha subunit
D5400_08010	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_08025	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D5400_08040	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_08055	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
D5400_08060	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
D5400_08065	ENOG4105C7W	Xanthine dehydrogenase
D5400_08075	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_08085	ENOG4108NDG	TRAP dicarboxylate
D5400_08110	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
D5400_08115	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
D5400_08120	ENOG4108IJ8	ABC transporter
D5400_08125	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
D5400_08130	ENOG4105CNG	UPF0061 protein
D5400_08135	ENOG4108TXN	phosphonate metabolism protein
D5400_08140	ENOG4105FD8	phosphonate metabolism protein PhnM
D5400_08150	ENOG4108IJ7	Glycine betaine
D5400_08165	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
D5400_08170	ENOG4105CBG	Sulfatase
D5400_08175	ENOG4105C26	Dehydrogenase
D5400_08180	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
D5400_08185	ENOG4105NWF	RbsD or FucU transport
D5400_08195	ENOG4105C7K	acetolactate synthase
D5400_08200	ENOG4105E5G	Alpha beta hydrolase fold
D5400_08215	ENOG4108VNY	MOSC domain protein
D5400_08225	ENOG4105SYT	Methylenetetrahydrofolate reductase
D5400_08235	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
D5400_08255	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
D5400_08280	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
D5400_08285	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
D5400_08300	ENOG4108206	Cell division protein mraZ
D5400_08305	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
D5400_08320	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
D5400_08330	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
D5400_08335	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
D5400_08345	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
D5400_08350	ENOG4105DFU	Cell wall formation (By similarity)
D5400_08355	ENOG4105D4A	Cell wall formation (By similarity)
D5400_08360	ENOG4105CPF	Cell wall formation (By similarity)
D5400_08365	ENOG4108UFP	Essential cell division protein (By similarity)
D5400_08370	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
D5400_08375	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
D5400_08380	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D5400_08385	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D5400_08395	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
D5400_08410	ENOG4105DC7	peptidase M24
D5400_08415	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
D5400_08430	ENOG4105C26	Dehydrogenase
D5400_08440	ENOG4105N7H	Cytochrome
D5400_08445	ENOG4105DKB	L-sorbosone dehydrogenase
D5400_08460	ENOG4105C4R	Atp-dependent dna helicase
D5400_08475	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
D5400_08480	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
D5400_08490	ENOG4105KT7	mgtC SapB transporter
D5400_08500	ENOG4105FDF	Could be involved in DNA repair (By similarity)
D5400_08505	ENOG4105DQE	DNA ligase
D5400_08520	ENOG4105CMQ	Chloride channel
D5400_08530	ENOG4105CQB	FAD linked oxidase domain protein
D5400_08570	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
D5400_08580	ENOG4107RIZ	hflk protein
D5400_08585	ENOG4105EPW	hflc protein
D5400_08605	ENOG4105EAC	phosphoserine phosphatase
D5400_08610	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
D5400_08615	ENOG4105BZU	Histidine kinase
D5400_08625	ENOG4105C7K	acetolactate synthase
D5400_08630	ENOG4108ZP8	Acetolactate synthase small subunit
D5400_08640	ENOG4106CSM	Rv0623-like transcription factor
D5400_08645	ENOG4108BI7	Toxic component of a toxin-antitoxin (TA) module. A
D5400_08650	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
D5400_08655	ENOG4105EEF	Alkane 1-monooxygenase
D5400_08660	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
D5400_08665	ENOG4105XA0	heptosyltransferase ii
D5400_08670	ENOG4105D16	lipopolysaccharide heptosyltransferase i
D5400_08675	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
D5400_08685	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
D5400_08690	ENOG4105K56	Transcriptional regulator
D5400_08695	ENOG4108ZHJ	Organic hydroperoxide resistance protein
D5400_08700	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
D5400_08705	ENOG4105C8P	)-transporter
D5400_08725	ENOG4105W6J	BA14K family
D5400_08735	ENOG4105JAB	phenazine biosynthesis protein, phzf family
D5400_08775	ENOG4108RW8	Universal stress protein F
D5400_08800	ENOG4107VMU	Membrane
D5400_08805	ENOG4105EXU	Membrane
D5400_08810	ENOG4105CHH	sulfate transporter
D5400_08840	ENOG4105P8Q	Curli production assembly transport component CsgG
D5400_08880	ENOG4105C1G	acyl-Coa dehydrogenase
D5400_08885	ENOG4105ETT	transcriptional Regulator, LysR family
D5400_08905	ENOG4107RJ7	Glycosyl transferase (Group 1
D5400_08910	ENOG4107RJ7	Glycosyl transferase (Group 1
D5400_08920	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
D5400_08925	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
D5400_08930	ENOG41087SS	fad dependent oxidoreductase
D5400_08935	ENOG4107SET	aldo keto reductase
D5400_08965	ENOG4105C1G	acyl-Coa dehydrogenase
D5400_08980	ENOG4107QX3	carboxylase
D5400_09020	ENOG4105ECQ	AraC Family Transcriptional Regulator
D5400_09035	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
D5400_09050	ENOG4105DAE	Methylenetetrahydrofolate reductase
D5400_09070	ENOG4108Q52	Methyltransferase cognate corrinoid protein
D5400_09075	ENOG4105F5V	trimethylamine methyltransferase
D5400_09080	ENOG4105C3R	Methionine synthase
D5400_09100	ENOG4108IEG	Formate dehydrogenase Alpha subunit
D5400_09105	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
D5400_09155	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
D5400_09160	ENOG41081F0	Precorrin-8x methylmutase
D5400_09165	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
D5400_09170	ENOG4105DVK	Precorrin-2 c20-methyltransferase
D5400_09225	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D5400_09235	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
D5400_09240	ENOG4105J3Q	acyl carrier protein
D5400_09245	ENOG4105CPN	adenine deaminase
D5400_09250	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
D5400_09255	ENOG4105BZ8	glutamate synthase
D5400_09265	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
D5400_09270	ENOG4107SJI	Dehydrogenase
D5400_09285	ENOG4108R86	Transcriptional regulator
D5400_09290	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
D5400_09295	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
D5400_09305	ENOG4105CD3	dihydroorotase
D5400_09315	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
D5400_09320	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
D5400_09340	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
D5400_09360	ENOG41074H6	response regulator
D5400_09365	ENOG4105VDW	Csbd family
D5400_09390	ENOG4105C1G	acyl-Coa dehydrogenase
D5400_09395	ENOG4105CHR	reductase
D5400_09410	ENOG4105F4R	Transcriptional regulator mode
D5400_09415	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
D5400_09420	ENOG4105E0C	molybdate abc transporter
D5400_09425	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
D5400_09435	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
D5400_09440	ENOG4105DZ1	carboxypeptidase
D5400_09460	ENOG4105BZU	Histidine kinase
D5400_09530	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
D5400_09540	ENOG4108MVM	Transposase
D5400_09580	ENOG410841Q	phosphoesterase PA-phosphatase related protein
D5400_09655	ENOG4108IJF	Heavy metal efflux pump, CzcA
D5400_09740	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
D5400_09745	ENOG4105KST	dependent repressor
D5400_09750	ENOG4105W1Y	Transcriptional regulator
D5400_09760	ENOG4108ZX6	Electron transport protein SCO1 SenC
D5400_09785	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
D5400_09790	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
D5400_09800	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
D5400_09820	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
D5400_09840	ENOG4105PGM	cation diffusion facilitator family transporter
D5400_09850	ENOG4105C59	p-type ATPase
D5400_09865	ENOG4107Y80	Major Facilitator superfamily
D5400_09905	ENOG4107STQ	Multicopper oxidase
D5400_09930	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
D5400_09950	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
D5400_09960	ENOG4105JZC	GHMP kinase
D5400_09965	ENOG4105DUM	transcriptional regulator, lysR family
D5400_10000	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D5400_10010	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
D5400_10015	ENOG4105FB2	class II Aldolase
D5400_10020	ENOG4105G63	Type III effector Hrp-dependent
D5400_10025	ENOG4105ZXK	Dehydrogenase
D5400_10030	ENOG4105EXW	epimerase dehydratase
D5400_10040	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_10050	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
D5400_10055	ENOG41073TP	transcriptional regulator
D5400_10060	ENOG4105C26	Dehydrogenase
D5400_10065	ENOG4108QBF	Transcriptional regulator
D5400_10070	ENOG4106J7G	oxidoreductase
D5400_10075	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
D5400_10090	ENOG4105D65	subunit l
D5400_10095	ENOG4108ZE9	Monovalent cation H antiporter subunit C
D5400_10100	ENOG4107R4Z	monovalent cation h antiporter subunit d
D5400_10105	ENOG4105SC1	monovalent cation H antiporter subunit E
D5400_10110	ENOG4105W4C	monovalent cation H antiporter subunit F
D5400_10115	ENOG4105KJM	monovalent cation h antiporter subunit g
D5400_10135	ENOG4108UYE	Lactoylglutathione lyase
D5400_10145	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
D5400_10150	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
D5400_10165	ENOG4105RD8	TRAP dicarboxylate transporter
D5400_10195	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
D5400_10200	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D5400_10205	ENOG4105C32	Amino acid ABC transporter (Permease)
D5400_10210	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
D5400_10215	ENOG4105C0Z	ABC transporter
D5400_10220	ENOG4108IV0	ABC, transporter
D5400_10250	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D5400_10255	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
D5400_10265	ENOG4105P0T	Usg family
D5400_10275	ENOG4107QI1	Mate efflux family protein
D5400_10280	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
D5400_10285	ENOG4108YZ9	Urea amidohydrolase subunit gamma
D5400_10290	ENOG4105KI2	Urea amidohydrolase subunit beta
D5400_10300	ENOG4105CQM	Urea amidohydrolase subunit alpha
D5400_10315	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
D5400_10325	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
D5400_10355	ENOG4105C1J	atp-dependent rna helicase
D5400_10360	ENOG4105CP9	extracellular ligand-binding receptor
D5400_10365	ENOG4105BZU	Histidine kinase
D5400_10375	ENOG4105C32	Amino acid ABC transporter (Permease)
D5400_10380	ENOG4108IV0	ABC, transporter
D5400_10385	ENOG4105C0Z	ABC transporter
D5400_10390	ENOG4105GIJ	Glycine betaine
D5400_10395	ENOG4108HQS	Glycine betaine
D5400_10400	ENOG4108IJ7	Glycine betaine
D5400_10405	ENOG4105BZU	Histidine kinase
D5400_10410	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
D5400_10415	ENOG4108DN8	FAD dependent oxidoreductase
D5400_10430	ENOG4105DHG	Allantoate amidinohydrolase
D5400_10440	ENOG4105VT2	5-hydroxyisourate hydrolase
D5400_10445	ENOG4107QUY	Guanine deaminase
D5400_10455	ENOG4105ETT	transcriptional Regulator, LysR family
D5400_10470	ENOG4105C7W	Xanthine dehydrogenase
D5400_10495	ENOG4105C32	Amino acid ABC transporter (Permease)
D5400_10505	ENOG4105C0Z	ABC transporter
D5400_10510	ENOG4108IV0	ABC, transporter
D5400_10515	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D5400_10530	ENOG4105F1J	Homogentisate 1,2-dioxygenase
D5400_10560	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
D5400_10570	ENOG4105CPC	Aldo Keto reductase
D5400_10580	ENOG4105NXV	High-affinity zinc uptake system protein
D5400_10585	ENOG4105FDK	ABC transporter
D5400_10590	ENOG4105FAV	ABC, transporter
D5400_10595	ENOG4105MYN	Zinc uptake regulation protein
D5400_10600	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
D5400_10605	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D5400_10615	ENOG4105VEQ	Cold shock protein
D5400_10630	ENOG4105BZU	Histidine kinase
D5400_10635	ENOG4108K3A	Glutathione S-transferase
D5400_10640	ENOG4108RG0	uracil-dna glycosylase
D5400_10645	ENOG4108XM1	transcriptional regulator AsnC family
D5400_10655	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D5400_10665	ENOG4105BZU	Histidine kinase
D5400_10670	ENOG41074H6	response regulator
D5400_10675	ENOG410903D	sensor protein
D5400_10690	ENOG4106PMH	Extracellular solute-binding protein family 3
D5400_10695	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
D5400_10705	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
D5400_10710	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
D5400_10715	ENOG4105C2C	drug resistance transporter, Bcr CflA
D5400_10750	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
D5400_10765	ENOG4105BZU	Histidine kinase
D5400_10775	ENOG4105BZU	Histidine kinase
D5400_10780	ENOG4105NAU	thioesterase Superfamily protein
D5400_10800	ENOG4105PGM	cation diffusion facilitator family transporter
D5400_10805	ENOG4105CHH	sulfate transporter
D5400_10810	ENOG4107SDU	Methyl-accepting chemotaxis
D5400_10825	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
D5400_10845	ENOG4105CHP	RNA polymerase
D5400_10850	ENOG4105GRZ	Ycii-related protein
D5400_10860	ENOG4105EV8	ectoine hydroxylase
D5400_10865	ENOG4105HF0	Membrane
D5400_10880	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
D5400_10885	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
D5400_10895	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
D5400_10900	ENOG41080IJ	Diacylglycerol kinase
D5400_10910	ENOG4105C4K	Nad synthetase
D5400_10920	ENOG4105E3A	(ABC) transporter
D5400_10925	ENOG4105DA5	(ABC) transporter
D5400_10930	ENOG4105K5G	30S ribosomal protein S21
D5400_10945	ENOG4105C6K	Malic enzyme
D5400_10950	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
D5400_10960	ENOG4105D8G	Major Facilitator superfamily
D5400_10970	ENOG4105DHJ	ABC, transporter
D5400_10980	ENOG4108SNX	Mammalian cell entry related domain protein
D5400_10995	ENOG4107Z7P	Ferredoxin
D5400_11000	ENOG4105CAY	ferredoxin--nadp reductase
D5400_11010	ENOG4105EEI	dihydropteroate synthase
D5400_11020	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D5400_11030	ENOG4106K28	UPF0283 membrane protein
D5400_11035	ENOG4105CM6	amino acid regulated cytosolic protein
D5400_11045	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D5400_11070	ENOG4108ZG0	Ompa motb domain protein
D5400_11080	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
D5400_11090	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
D5400_11095	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
D5400_11105	ENOG4105CSV	Glutaminase
D5400_11130	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
D5400_11140	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
D5400_11150	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
D5400_11155	ENOG4105C2C	drug resistance transporter, Bcr CflA
D5400_11160	ENOG4105C2C	drug resistance transporter, Bcr CflA
D5400_11175	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
D5400_11200	ENOG410839H	phosphoribosylformylglycinamidine synthase
D5400_11205	ENOG4107QPR	SAICAR synthetase
D5400_11230	ENOG4105C83	adenylosuccinate lyase
D5400_11235	ENOG4105DJV	ribulose-phosphate 3-epimerase
D5400_11240	ENOG4105KXX	peptidase s58 dmpa
D5400_11250	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
D5400_11255	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
D5400_11270	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
D5400_11290	ENOG4105C0B	DNA polymerase III (alpha subunit)
D5400_11300	ENOG4105C0H	protease
D5400_11305	ENOG4105D1H	recombination factor protein RarA
D5400_11320	ENOG4105BZU	Histidine kinase
D5400_11330	ENOG4105BZU	Histidine kinase
D5400_11340	ENOG41082CG	Protein CrcB homolog
D5400_11345	ENOG4105EI2	Pseudouridine synthase
D5400_11355	ENOG4107QX3	carboxylase
D5400_11380	ENOG4105C4W	S-formylglutathione hydrolase
D5400_11385	ENOG4108UPT	UPF0178 protein
D5400_11390	ENOG4105E66	phosphoriboisomerase A
D5400_11400	ENOG4105DC8	reductase
D5400_11415	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
D5400_11450	ENOG4105RK9	auxin efflux carrier
D5400_11460	ENOG4105VE1	Phosphatidylcholine synthase
D5400_11465	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
D5400_11470	ENOG4108JQ9	ABC transporter
D5400_11475	ENOG4105UIB	(ABC) transporter
D5400_11490	ENOG4105BZS	acriflavin resistance protein
D5400_11505	ENOG4105D78	K07001 NTE family protein
D5400_11510	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
D5400_11515	ENOG4105EUJ	GTP cyclohydrolase i
D5400_11525	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
D5400_11530	ENOG4105C22	threonyL-tRNA synthetase
D5400_11545	ENOG4105EW6	flavin reductase domain protein, FMN-binding
D5400_11550	ENOG4105CI0	Citrate lyase
D5400_11565	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D5400_11665	ENOG4105Y2X	UPF0335 protein
D5400_11805	ENOG4105KPY	Small multidrug resistance protein
D5400_11810	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
D5400_11815	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
D5400_11825	ENOG4105DHZ	alpha beta
D5400_11830	ENOG4105C3J	Cysteine desulfurase
D5400_11840	ENOG4105C3K	feS assembly ATPase SufC
D5400_11845	ENOG4105JRK	feS assembly protein SufD
D5400_11855	ENOG4105VG1	fes assembly suf system protein
D5400_11860	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
D5400_11870	ENOG4105CH5	extracellular solute-binding protein, family 7
D5400_11875	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_11890	ENOG4105C1J	atp-dependent rna helicase
D5400_11895	ENOG4105DR5	peptidase
D5400_11900	ENOG4105ED9	Protein of unknown function (DUF455)
D5400_11905	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D5400_11915	ENOG4105C2N	RNA methyltransferase TrmH family group 3
D5400_11945	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D5400_11960	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
D5400_11980	ENOG4105VN1	Heat shock protein
D5400_12010	ENOG4105C0H	protease
D5400_12020	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
D5400_12030	ENOG4105FDP	GntR family transcriptional regulator
D5400_12035	ENOG4105CP9	extracellular ligand-binding receptor
D5400_12040	ENOG4105C32	Amino acid ABC transporter (Permease)
D5400_12045	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
D5400_12050	ENOG4105C0Z	ABC transporter
D5400_12055	ENOG4108IV0	ABC, transporter
D5400_12060	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D5400_12065	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D5400_12085	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
D5400_12090	ENOG4107EFR	Flavocytochrome c
D5400_12100	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
D5400_12120	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
D5400_12125	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
D5400_12130	ENOG4108VZM	50s ribosomal protein L10
D5400_12135	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
D5400_12140	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D5400_12145	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D5400_12155	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
D5400_12160	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
D5400_12165	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
D5400_12170	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
D5400_12175	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
D5400_12180	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
D5400_12185	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
D5400_12190	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
D5400_12195	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D5400_12200	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
D5400_12205	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
D5400_12210	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
D5400_12215	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
D5400_12220	ENOG41083MP	50s ribosomal protein l29
D5400_12225	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
D5400_12230	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
D5400_12235	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
D5400_12240	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D5400_12245	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
D5400_12250	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
D5400_12255	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
D5400_12260	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
D5400_12265	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
D5400_12270	ENOG41084HQ	50S ribosomal protein L30
D5400_12275	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
D5400_12285	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
D5400_12290	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D5400_12295	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
D5400_12300	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D5400_12305	ENOG4108ZT0	50S ribosomal protein l17
D5400_12325	ENOG4107RTZ	reductase
D5400_12335	ENOG4105CJ3	phosphate transporter
D5400_12345	ENOG4105CHR	reductase
D5400_12350	ENOG4105CF7	AraC family transcriptional regulator
D5400_12355	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
D5400_12360	ENOG4107TH8	cina domain protein
D5400_12390	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D5400_12400	ENOG4105BZU	Histidine kinase
D5400_12405	ENOG4107GFK	fumarate
D5400_12410	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
D5400_12415	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D5400_12420	ENOG4107QPD	alcohol dehydrogenase
D5400_12435	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D5400_12440	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
D5400_12535	ENOG4105Y2X	UPF0335 protein
D5400_12590	ENOG4105D07	Signal peptide peptidase, SppA
D5400_12735	ENOG4105CJW	magnesium transporter
D5400_12750	ENOG4105CV8	reductase
D5400_12760	ENOG4105EJQ	L-serine dehydratase
D5400_12790	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
D5400_12810	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
D5400_12820	ENOG4105CUX	Signal transduction histidine kinase
D5400_12825	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D5400_12830	ENOG4105ES5	Histidine kinase
D5400_12835	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D5400_12865	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D5400_12885	ENOG4105GRZ	Ycii-related protein
D5400_12910	ENOG4105DZ1	carboxypeptidase
D5400_12915	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
D5400_12925	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
D5400_12930	ENOG4105F8V	Hydrolase, tatD family
D5400_12935	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
D5400_12945	ENOG4105DXN	mazG family
D5400_12950	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
D5400_12955	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
D5400_12960	ENOG4105F0I	Aminotransferase
D5400_12965	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
D5400_12970	ENOG4105C1A	potassium transporter peripheral membrane
D5400_12975	ENOG4105JVC	membrAne
D5400_12985	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
D5400_12990	ENOG4108UUM	single-stranded DNA-binding protein
D5400_12995	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
D5400_13000	ENOG4108U78	Glutathione S-transferase
D5400_13015	ENOG4105C5F	glutamine synthetase
D5400_13025	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D5400_13035	ENOG4108V0P	LemA family
D5400_13045	ENOG4105D8X	mechanosensitive ion channel
D5400_13055	ENOG4105C26	Dehydrogenase
D5400_13075	ENOG4105C1G	acyl-Coa dehydrogenase
D5400_13090	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
D5400_13100	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D5400_13110	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
D5400_13115	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
D5400_13125	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D5400_13130	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D5400_13135	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
D5400_13145	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D5400_13150	ENOG4105GYT	Protein of unknown function (DUF1009)
D5400_13155	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D5400_13160	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
D5400_13165	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D5400_13170	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D5400_13175	ENOG4105DZP	Membrane-associated zinc metalloprotease
D5400_13185	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
D5400_13190	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
D5400_13195	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
D5400_13200	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
D5400_13205	ENOG4105CE9	30S ribosomal protein S2
D5400_13210	ENOG4105BZU	Histidine kinase
D5400_13230	ENOG4108NWD	Cytochrome
D5400_13235	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
D5400_13265	ENOG4105K59	histidine triad (HIT) protein
D5400_13270	ENOG4108Z1B	Cyclase dehydrase
D5400_13275	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
D5400_13285	ENOG4107QN2	dihydrolipoyl dehydrogenase
D5400_13295	ENOG4105C7S	Dehydrogenase
D5400_13300	ENOG4105CPP	Dehydrogenase, E1 component
D5400_13305	ENOG4108JYK	Dehydrogenase
D5400_13340	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
D5400_13350	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D5400_13370	ENOG4108Z0R	Transferase
D5400_13385	ENOG4105D7W	serine acetyltransferase
D5400_13395	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
D5400_13410	ENOG4105CDA	abc transporter atp-binding protein
D5400_13415	ENOG4105DRP	amino acid AbC transporter
D5400_13420	ENOG4105EZ7	amino acid ABC transporter
D5400_13425	ENOG4107QXX	ABC transporter
D5400_13430	ENOG4105C28	cystathionine
D5400_13445	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
D5400_13455	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
D5400_13465	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
D5400_13475	ENOG4105CP7	Triose-phosphate isomerase
D5400_13480	ENOG4105EIN	peptidylprolyl cis-trans isomerase
D5400_13485	ENOG4107QYG	anthranilate phosphoribosyltransferase
D5400_13490	ENOG4105DK0	Indole-3-glycerol phosphate synthase
D5400_13495	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D5400_13500	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
D5400_13505	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
D5400_13510	ENOG4108EC8	DNA internalization-related competence protein ComEC
D5400_13525	ENOG41081FY	multiple antibiotic resistance (MarC)-related
D5400_13550	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
D5400_13555	ENOG4105C03	ribonuclease
D5400_13555	ENOG4105C03	ribonuclease
D5400_13575	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
D5400_13580	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
D5400_13585	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D5400_13590	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
D5400_13615	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
D5400_13620	ENOG4105PW4	Sugar fermentation stimulation protein homolog
D5400_13625	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
D5400_13630	ENOG4105W5Q	DNA repair protein (RadC
D5400_13635	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
D5400_13640	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
D5400_13665	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
D5400_13710	ENOG4108K5P	(LipO)protein
D5400_13715	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
D5400_13720	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
D5400_13725	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
D5400_13730	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
D5400_13740	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
D5400_13745	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
D5400_13750	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
D5400_13755	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
D5400_13765	ENOG4105C75	arginyL-tRNA synthetase
D5400_13770	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
D5400_13785	ENOG4105CGK	Exodeoxyribonuclease III
D5400_13795	ENOG4108P7N	Exopolysaccharide production negative regulator
D5400_13800	ENOG4105C01	Dihydroxy-acid dehydratase
D5400_13810	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
D5400_13825	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
D5400_13840	ENOG4107QMS	site-determining protein
D5400_13865	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D5400_13880	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
D5400_13885	ENOG4105CT4	transporter
D5400_13890	ENOG4105EMU	Dehydrogenase
D5400_13895	ENOG4108NIX	Factor ChrR
D5400_13900	ENOG4105C6T	cysteine synthase
D5400_13910	ENOG4105KHC	sulfurtransferase
D5400_13920	ENOG4105DCF	alanine dehydrogenase
D5400_13925	ENOG4108YXU	transcriptional regulator AsnC family
D5400_13930	ENOG4107SFI	Major Facilitator superfamily
D5400_13940	ENOG4105CGH	5'-nucleotidase
D5400_13950	ENOG4107NKQ	Flavinator of succinate dehydrogenase
D5400_13955	ENOG4105CB5	ATP-dependent DNA helicase recG
D5400_13965	ENOG4107QIV	Cytochrome c biogenesis protein
D5400_14185	ENOG4105Y2X	UPF0335 protein
D5400_14300	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
D5400_14310	ENOG4105VEQ	Cold shock protein
D5400_14315	ENOG4108UYE	Lactoylglutathione lyase
D5400_14330	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
D5400_14335	ENOG4105D6E	homoserine dehydrogenase
D5400_14340	ENOG4105CHM	Aminotransferase
D5400_14350	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
D5400_14360	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
D5400_14370	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
D5400_14375	ENOG4105BZU	Histidine kinase
D5400_14380	ENOG4107T8T	UPF0173 metal-dependent hydrolase
D5400_14385	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
D5400_14405	ENOG4105CSU	acyl-Coa dehydrogenase
D5400_14410	ENOG4105CXT	aspartate transcarbamylase
D5400_14425	ENOG4105C79	DNA protecting protein DprA
D5400_14435	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
D5400_14440	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
D5400_14460	ENOG4105W0E	50S ribosomal protein L33
D5400_14465	ENOG4105BZU	Histidine kinase
D5400_14470	ENOG4108UXN	response regulator
D5400_14485	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
D5400_14500	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D5400_14505	ENOG4105D60	lipoprotein releasing system transmembrane protein
D5400_14510	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
D5400_14535	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D5400_14540	ENOG4105C8S	subunit m
D5400_14545	ENOG4105D65	subunit l
D5400_14550	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D5400_14555	ENOG4105DF2	NADH dehydrogenase subunit j
D5400_14560	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D5400_14565	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
D5400_14570	ENOG4107R0R	NADH dehydrogenase subunit g
D5400_14580	ENOG4107QIZ	NADH dehydrogenase
D5400_14585	ENOG4105GKE	subunit e
D5400_14595	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D5400_14600	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D5400_14605	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D5400_14610	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D5400_14635	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
D5400_14645	ENOG4105EU8	FAD linked oxidase domain protein
D5400_14650	ENOG4105CQB	FAD linked oxidase domain protein
D5400_14655	ENOG4105HEI	LysR family (Transcriptional regulator
D5400_14665	ENOG41073TP	transcriptional regulator
D5400_14670	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
D5400_14675	ENOG4107QR9	Iron-sulfur cluster binding protein
D5400_14680	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
D5400_14715	ENOG4107NQ8	LysR family Transcriptional regulator
D5400_14720	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D5400_14725	ENOG4105CKW	Inner membrane protein yedI
D5400_14735	ENOG4107S8C	mandelate racemase muconate lactonizing
D5400_14740	ENOG4105DEF	Extracellular solute-binding protein, family 5
D5400_14745	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
D5400_14750	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D5400_14755	ENOG4105C3U	ABC transporter
D5400_14760	ENOG4108JQ7	(ABC) transporter
D5400_14765	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D5400_14775	ENOG4105K70	DNA-binding protein
D5400_14780	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
D5400_14785	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
D5400_14790	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
D5400_14800	ENOG4106A3M	Cytochrome p-450
D5400_14815	ENOG4105K4P	CoA-binding domain protein
D5400_14825	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
D5400_14830	ENOG4105D7T	ABC transporter
D5400_14845	ENOG4105JSC	dimethylmenaquinone methyltransferase
D5400_14850	ENOG4105E39	Enoyl-CoA hydratase
D5400_14860	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
D5400_14865	ENOG4108UJD	30S ribosomal protein S9
D5400_14875	ENOG4107SQ0	N-acetyl-gamma-glutamyl-phosphate reductase
D5400_14880	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
D5400_14910	ENOG4105D3Q	Sugar transferase
D5400_14925	ENOG4105CPC	Aldo Keto reductase
D5400_14940	ENOG4105WJX	transcriptional regulator MERR family
D5400_14945	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D5400_14950	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D5400_14955	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
D5400_14975	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
D5400_14980	ENOG4105DXI	Major Facilitator superfamily
D5400_14985	ENOG4107XZX	Involved in the transcription termination process (By similarity)
D5400_14990	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
D5400_15000	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
D5400_15010	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
D5400_15015	ENOG41075H3	AraC family transcriptional regulator
D5400_15030	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
D5400_15045	ENOG4105D52	delta-aminolevulinic acid dehydratase
D5400_15055	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
D5400_15060	ENOG41069B0	Membrane-bound lysozyme-inhibitor of c-type lysozyme
D5400_15065	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D5400_15075	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
D5400_15080	ENOG4105C9M	aspartyl-trna synthetase
D5400_15085	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
D5400_15100	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
D5400_15110	ENOG4105C02	permease
D5400_15120	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
D5400_15125	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
D5400_15130	ENOG4107QY8	reductase
D5400_15135	ENOG4105D6S	protein involved in catabolism of external DNA
D5400_15150	ENOG4108U78	Glutathione S-transferase
D5400_15155	ENOG4105JVC	membrAne
D5400_15165	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
D5400_15185	ENOG4108ZAF	Molybdopterin
D5400_15190	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
D5400_15195	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
D5400_15205	ENOG4105C5H	ABC transporter
D5400_15215	ENOG4107QUT	magnesium and cobalt transport protein CorA
D5400_15225	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D5400_15240	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
D5400_15250	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
D5400_15255	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
D5400_15260	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
D5400_15265	ENOG4105DSJ	YicC domain protein
D5400_15270	ENOG4105HHA	aminodeoxychorismate lyase
D5400_15275	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D5400_15280	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D5400_15290	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
D5400_15300	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
D5400_15305	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
D5400_15315	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
D5400_15320	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
D5400_15330	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
D5400_15345	ENOG4105X54	addiction module antidote protein
D5400_15370	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
D5400_15375	ENOG4105PDP	Short chain dehydrogenase
D5400_15380	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
D5400_15385	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
D5400_15390	ENOG4108JJ7	ABC transporter
D5400_15405	ENOG4108URH	decarboxylase
D5400_15410	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
D5400_15420	ENOG4105FR1	rard protein
D5400_15425	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
D5400_15445	ENOG4105C8N	cysteinyl-tRNA synthetase
D5400_15485	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
D5400_15490	ENOG4108R7K	Metal Dependent Phosphohydrolase
D5400_15510	ENOG4108WQI	RNA Polymerase
D5400_15520	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
D5400_15525	ENOG4108IYU	L-aspartate oxidase
D5400_15530	ENOG4105T4X	n-acetylmuramoyl-l-alanine amidase
D5400_15535	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
D5400_15555	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
D5400_15560	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
D5400_15565	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
D5400_15570	ENOG4105C3F	Signal peptidase i
D5400_15575	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
D5400_15590	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
D5400_15600	ENOG4105E50	uracil-dna glycosylase
D5400_15615	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
D5400_15620	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D5400_15625	ENOG4107SC1	transglycosylase
D5400_15640	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
D5400_15645	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
D5400_15650	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D5400_15690	ENOG4105BZ1	(ABC) transporter
D5400_15695	ENOG4105CQZ	Histidine kinase
D5400_15700	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D5400_15725	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D5400_15735	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
D5400_15740	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
D5400_15750	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
D5400_15800	ENOG4105EMU	Dehydrogenase
D5400_15810	ENOG41084CK	capsule polysaccharide
D5400_15890	ENOG4105CFI	type iii restriction protein res subunit
D5400_15925	ENOG4108ES9	ParB domain protein nuclease
D5400_16075	ENOG4107QPB	Beta-lactamase domain protein
D5400_16080	ENOG4107QPB	Beta-lactamase domain protein
D5400_16090	ENOG4105DHQ	Histidine kinase
D5400_16095	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
D5400_16100	ENOG4108PXI	ErfK YbiS YcfS YnhG
D5400_16105	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
D5400_16110	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D5400_16135	ENOG4105CPU	Monooxygenase
D5400_16140	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
D5400_16145	ENOG4105E2Y	ABC, transporter
D5400_16150	ENOG4108HW3	(ABC) transporter
D5400_16155	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
D5400_16160	ENOG4108UMI	ABC transporter, permease
D5400_16165	ENOG4105D01	(LipO)protein
D5400_16170	ENOG4108UZX	fmn reductase
D5400_16195	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
D5400_16200	ENOG4108UZX	fmn reductase
D5400_16205	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
D5400_16320	ENOG4105CHR	reductase
D5400_16330	ENOG410642W	LysR family Transcriptional regulator
D5400_16340	ENOG4107QZ7	Cellulose synthase catalytic subunit
D5400_16350	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
D5400_16365	ENOG4107VXZ	Hydrolase
D5400_16380	ENOG4105BZU	Histidine kinase
D5400_16385	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
D5400_16395	ENOG4105E0A	ABC, transporter
D5400_16400	ENOG4105E0K	tonB-dependent siderophore receptor
D5400_16405	ENOG4105RK9	auxin efflux carrier
D5400_16410	ENOG4105W39	Membrane
D5400_16415	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D5400_16435	ENOG4105CYM	Glutathione S-transferase
D5400_16440	ENOG4105DSF	transport protein
D5400_16450	ENOG4105FYV	Amp nucleosidase
D5400_16470	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
D5400_16475	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
D5400_16485	ENOG4105RAK	Histidine kinase
D5400_16490	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D5400_16505	ENOG4105CD8	aminopeptidase N
D5400_16510	ENOG4105BZU	Histidine kinase
D5400_16520	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
D5400_16525	ENOG4105GR3	Histidine kinase
D5400_16535	ENOG4105C0H	protease
D5400_16540	ENOG4105KWW	Biogenesis protein
D5400_16545	ENOG4105DA4	cytochrome c-type biogenesis protein
D5400_16550	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
D5400_16555	ENOG4106FI7	cytochrome c-type biogenesis protein
D5400_16565	ENOG4105DHQ	Histidine kinase
D5400_16570	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
D5400_16610	ENOG4108ZZ3	UPF0260 protein
D5400_16615	ENOG4108JQC	penicillin-binding protein 1A
D5400_16645	ENOG4105BZU	Histidine kinase
D5400_16650	ENOG4105WZR	
D5400_16655	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
D5400_16670	ENOG4108YXV	Transcriptional regulator
D5400_16675	ENOG4105KJM	monovalent cation h antiporter subunit g
D5400_16680	ENOG41080TA	Multiple resistance and ph regulation protein f
D5400_16685	ENOG4105SC1	monovalent cation H antiporter subunit E
D5400_16690	ENOG4108JPZ	Monovalent cation H antiporter subunit D
D5400_16695	ENOG4108ZE9	Monovalent cation H antiporter subunit C
D5400_16700	ENOG4105GND	monovalent cation H antiporter subunit B
D5400_16705	ENOG4105D65	subunit l
D5400_16710	ENOG4105E0X	reductase
D5400_16725	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
D5400_16735	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D5400_16740	ENOG4105CM2	brancheD-chain amino acid aminotransferase
D5400_16750	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
D5400_16755	ENOG4105D7A	ATP-binding protein
D5400_16785	ENOG4108Z9Z	response to DNA damage stimulus
D5400_16805	ENOG4105CHR	reductase
D5400_16820	ENOG4105F38	ABC transporter, permease
D5400_16825	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D5400_16830	ENOG4107RUE	extracellular solute-binding protein family 1
D5400_16835	ENOG4105CQZ	Histidine kinase
D5400_17010	ENOG4105EFC	phage portal protein HK97 family
D5400_17070	ENOG4105Y2X	UPF0335 protein
D5400_17145	ENOG4105DJG	MaoC domain protein dehydratase
D5400_17155	ENOG4108PXI	ErfK YbiS YcfS YnhG
D5400_17170	ENOG4105VKD	bioY protein
D5400_17200	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
D5400_17210	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
D5400_17215	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
D5400_17225	ENOG4105CEN	a g-specific adenine glycosylase
D5400_17235	ENOG4105CEC	DNA methylase N-4 N-6
D5400_17240	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
D5400_17250	ENOG4105D98	threonine synthase
D5400_17255	ENOG4105C1V	Peptidase, M16
D5400_17260	ENOG4105D9U	N-acetyltransferase
D5400_17265	ENOG4105BZU	Histidine kinase
D5400_17270	ENOG4108UJU	UPF0301 protein
D5400_17280	ENOG4105EHV	domain protein
D5400_17285	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D5400_17290	ENOG4105CUV	Homoserine Kinase
D5400_17295	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
D5400_17310	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
D5400_17315	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
D5400_17320	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
D5400_17325	ENOG4105BZ9	Cytochrome C oxidase, subunit I
D5400_17330	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
D5400_17340	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
D5400_17345	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
D5400_17355	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
D5400_17365	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D5400_17370	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
D5400_17375	ENOG4107TB6	phosphoglycerate mutase
D5400_17380	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
D5400_17385	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
D5400_17395	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D5400_17400	ENOG4105BZU	Histidine kinase
D5400_17405	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
D5400_17420	ENOG4107QS4	23S rRNA
D5400_17425	ENOG4105E39	Enoyl-CoA hydratase
D5400_17430	ENOG4105CSU	acyl-Coa dehydrogenase
D5400_17435	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D5400_17455	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
D5400_17460	ENOG4105C12	Phosphoribosylglycinamide synthetase
D5400_17470	ENOG4105KWG	Pfam:DUF1696
D5400_17475	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
D5400_17505	ENOG4105EAH	synthase
D5400_17515	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
D5400_17520	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
D5400_17535	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D5400_17540	ENOG4105N5Q	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
D5400_17545	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D5400_17550	ENOG4105VD1	ATP synthase subunit C
D5400_17555	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
D5400_17560	ENOG4107PQ6	Inherit from NOG: atp synthase
D5400_17570	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
D5400_17590	ENOG4105CBP	Major Facilitator
D5400_17610	ENOG4105DU1	integral membrane protein, terc
D5400_17635	ENOG4105VP2	Transcriptional regulator, Crp Fnr family
D5400_17645	ENOG4108ZXC	Two component transcriptional regulator, luxr family
D5400_17650	ENOG4105BZU	Histidine kinase
D5400_17655	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D5400_17675	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
D5400_17695	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
D5400_17700	ENOG4105C9X	ppx gppa phosphatase
D5400_17720	ENOG4105C4R	Atp-dependent dna helicase
D5400_17730	ENOG4105BZU	Histidine kinase
D5400_17770	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_17780	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
D5400_17800	ENOG4107S9F	NmrA family
D5400_17805	ENOG41062KD	Inherit from COG: ketosteroid isomerase-like protein
D5400_17810	ENOG4108JGH	Tetr family transcriptional regulator
D5400_17820	ENOG4108IXY	short-chain dehydrogenase reductase
D5400_17835	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
D5400_17845	ENOG4105EQ2	LysR family Transcriptional regulator
D5400_17850	ENOG4105EMU	Dehydrogenase
D5400_17860	ENOG4105KBX	Transcriptional regulator, TetR family
D5400_17870	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
D5400_17875	ENOG4105DHQ	Histidine kinase
D5400_17885	ENOG4105F6J	Alpha beta hydrolase fold
D5400_17890	ENOG4108QBF	Transcriptional regulator
D5400_17895	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
D5400_17905	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_17915	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
D5400_17935	ENOG4108IXY	short-chain dehydrogenase reductase
D5400_17995	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
D5400_18000	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
D5400_18005	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
D5400_18010	ENOG4105C08	Histidine kinase
D5400_18015	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
D5400_18020	ENOG4107QWB	Ornithine cyclodeaminase
D5400_18030	ENOG4105EW9	transcriptional regulator AsnC family
D5400_18065	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D5400_18105	ENOG4108JUA	Transcriptional regulator
D5400_18125	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
D5400_18145	ENOG4105E39	Enoyl-CoA hydratase
D5400_18175	ENOG4105ETE	Transcriptional regulator (LacI family
D5400_18180	ENOG4105C2J	ABC transporter
D5400_18185	ENOG4105D4B	ABC, transporter
D5400_18190	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
D5400_18195	ENOG4105CNN	ABC, transporter
D5400_18200	ENOG4105D7K	pfkb domain protein
D5400_18210	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D5400_18215	ENOG4105H3G	oxidoreductase
D5400_18235	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
D5400_18250	ENOG4107SQD	Transcriptional regulator, GntR family
D5400_18280	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
D5400_18285	ENOG4105EAB	amino acid AbC transporter
D5400_18290	ENOG4105E5Q	amino acid AbC transporter
D5400_18300	ENOG4108UDW	Transcriptional regulator, luxr family
D5400_18315	ENOG4105CGK	Exodeoxyribonuclease III
D5400_18330	ENOG4105WH1	Two component transcriptional regulator luxr family
D5400_18345	ENOG4107SET	aldo keto reductase
D5400_18355	ENOG4105CMT	Dihydroxyacetone kinase
D5400_18360	ENOG4105CNN	ABC, transporter
D5400_18365	ENOG4105C2J	ABC transporter
D5400_18370	ENOG4105D4B	ABC, transporter
D5400_18375	ENOG4108EMV	Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity)
D5400_18380	ENOG4105CN9	Peptidase m42 family protein
D5400_18385	ENOG4105F5R	ABC transporter
D5400_18390	ENOG4106P19	photosystem i assembly btpa
D5400_18395	ENOG4105E98	transcriptional regulator DeoR family
D5400_18400	ENOG41073TP	transcriptional regulator
D5400_18405	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
D5400_18420	ENOG4108YZG	isomerase
D5400_18485	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
D5400_18500	ENOG4108IV0	ABC, transporter
D5400_18505	ENOG4105C0Z	ABC transporter
D5400_18515	ENOG4105C32	Amino acid ABC transporter (Permease)
D5400_18530	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
D5400_18540	ENOG4105C26	Dehydrogenase
D5400_18570	ENOG4108IV0	ABC, transporter
D5400_18575	ENOG4108IUZ	ABC transporter
D5400_18585	ENOG4107RQ0	Maleylacetate reductase
D5400_18595	ENOG4105W6J	BA14K family
D5400_18605	ENOG4108QDE	fad dependent oxidoreductase
D5400_18610	ENOG4105CHU	acetyl-coa acetyltransferase
D5400_18625	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
D5400_18630	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_18640	ENOG4105CH5	extracellular solute-binding protein, family 7
D5400_18650	ENOG4108MG3	formate dehydrogenase
D5400_18655	ENOG4105QAX	Iron-sulfur
D5400_18660	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
D5400_18710	ENOG4106S2D	Transcriptional regulator
D5400_18715	ENOG4105BZU	Histidine kinase
D5400_18740	ENOG4108I0Y	(ABC) transporter
D5400_18755	ENOG4105D6J	arsenicaL-resistance protein
D5400_18760	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
D5400_18775	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D5400_18790	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
D5400_18795	ENOG4105CHU	acetyl-coa acetyltransferase
D5400_18810	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
D5400_18815	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
D5400_18820	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
D5400_18825	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
D5400_18830	ENOG4105DDW	LysR family Transcriptional regulator
D5400_18835	ENOG4107WYG	Transcriptional regulator, luxr family
D5400_18840	ENOG4105CEY	Amp-dependent synthetase and ligase
D5400_18850	ENOG4105BZU	Histidine kinase
D5400_18860	ENOG4105CC5	ABC transporter
D5400_18865	ENOG4105CC5	ABC transporter
D5400_18870	ENOG4105DIK	(ABC) transporter
D5400_18875	ENOG4105DSE	periplasmic solute binding protein
D5400_18880	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
D5400_18890	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
D5400_18895	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
D5400_18910	ENOG4105ECY	inositol monophosphatase
D5400_18915	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
D5400_18930	ENOG4106H78	methyltransferase
D5400_18935	ENOG4105FE9	pseudouridine synthase
D5400_18940	ENOG4108Z6B	deaminase
D5400_18950	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
D5400_18955	ENOG4105DTN	riboflavin biosynthesis protein ribF
D5400_18965	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
D5400_18970	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
D5400_18975	ENOG4105KVH	Transcriptional regulator
D5400_18990	ENOG4105BZU	Histidine kinase
D5400_18995	ENOG4105CYM	Glutathione S-transferase
D5400_19000	ENOG410635A	Membrane
D5400_19005	ENOG4105C9Q	fumarate hydratase class II
D5400_19015	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
D5400_19020	ENOG4105P5X	ATP phosphoribosyltransferase regulatory subunit
D5400_19025	ENOG4105CUT	histidyl-tRNA synthetase
D5400_19045	ENOG4108R3E	Dna-3-methyladenine glycosylase i
D5400_19050	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
D5400_19055	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
D5400_19060	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
D5400_19080	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
D5400_19105	ENOG4105FCS	tRNA rRNA methyltransferase
D5400_19120	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D5400_19130	ENOG4105CPW	cytochrome b561
D5400_19145	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
D5400_19170	ENOG4108YZY	peptidylprolyl cis-trans isomerase
D5400_19220	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
D5400_19225	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
D5400_19230	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
D5400_19240	ENOG4105KCK	Peptidoglycan-associated lipoprotein
D5400_19245	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
D5400_19255	ENOG4108ZZF	transport protein (ExbD)
D5400_19260	ENOG4105E02	MotA TolQ exbB proton channel
D5400_19265	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
D5400_19270	ENOG4107YD3	Thioesterase
D5400_19295	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
D5400_19300	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
D5400_19305	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
D5400_19310	ENOG4105DEN	Luciferase family
D5400_19320	ENOG4105CDY	transcriptional regulatory protein
D5400_19340	ENOG4105EE5	Membrane protein terC
D5400_19345	ENOG4105D48	metallophosphoesterase
D5400_19380	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D5400_19385	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
D5400_19390	ENOG4105BZA	Phosphoglycerate kinase
D5400_19395	ENOG4107R1Y	fructose-bisphosphate aldolase
D5400_19410	ENOG4105M0T	TPR Repeat-Containing Protein
D5400_19415	ENOG4105YK5	50S ribosomal protein L36
D5400_19420	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
D5400_19440	ENOG4105MHT	Transcriptional regulator, ARSR family
D5400_19445	ENOG4105CEY	Amp-dependent synthetase and ligase
D5400_19470	ENOG4105ECY	inositol monophosphatase
D5400_19480	ENOG4105UYK	outer membrane protein a
D5400_19485	ENOG4105BZ1	(ABC) transporter
D5400_19490	ENOG41082FS	50S ribosomal protein L31
D5400_19515	ENOG4105CA9	Pyruvate kinase
D5400_19530	ENOG4105Y2X	UPF0335 protein
D5400_19535	ENOG4108TEB	UPF0114 protein
D5400_19545	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D5400_19570	ENOG4105FE5	Homospermidine synthase
D5400_19580	ENOG4105CGH	5'-nucleotidase
D5400_19585	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
D5400_19590	ENOG4105C2X	Arabinose 5-phosphate isomerase
D5400_19605	ENOG4105CVE	Lytic murein transglycosylase
D5400_19625	ENOG4105C5W	Aldolase
D5400_19635	ENOG4108ZNX	Heat shock protein
D5400_19640	ENOG4108EUD	Lysophospholipase
D5400_19685	ENOG4108HWW	ABC transporter
D5400_19690	ENOG4105C32	Amino acid ABC transporter (Permease)
D5400_19700	ENOG4108IV0	ABC, transporter
D5400_19705	ENOG4105C0Z	ABC transporter
D5400_19725	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
D5400_19735	ENOG4105DDR	sarcosine oxidase (Beta subunit)
D5400_19740	ENOG4105K5G	30S ribosomal protein S21
D5400_19750	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
D5400_19755	ENOG4105W8H	transhydrogenase (subunit alpha
D5400_19760	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
D5400_19775	ENOG4105BZU	Histidine kinase
D5400_19785	ENOG4105CHR	reductase
D5400_19790	ENOG4105CH5	extracellular solute-binding protein, family 7
D5400_19795	ENOG4108Z86	Glutamine amidotransferase
D5400_19800	ENOG4105C5I	Dehydrogenase
D5400_19805	ENOG4105ETE	Transcriptional regulator (LacI family
D5400_19825	ENOG4105CKI	cobalamin synthesis protein
D5400_19855	ENOG4105CC0	LysR family Transcriptional regulator
D5400_19910	ENOG4108UHU	Aldolase
D5400_19920	ENOG4105C72	UPF0176 protein
D5400_19930	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
D5400_19935	ENOG4105CNN	ABC, transporter
D5400_19940	ENOG4105C2J	ABC transporter
D5400_19955	ENOG4105ETE	Transcriptional regulator (LacI family
D5400_19960	ENOG4105C93	Xylose Isomerase
D5400_19965	ENOG4105CMG	Carbohydrate kinase
D5400_19970	ENOG4105ETE	Transcriptional regulator (LacI family
D5400_20000	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
D5400_20015	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D5400_20025	ENOG4105EHG	Permease protein
D5400_20030	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
D5400_20075	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
D5400_20115	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
D5400_20120	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
D5400_20125	ENOG4108I5D	sulfate abc transporter
D5400_20130	ENOG4105ECW	sulfate abc transporter
D5400_20135	ENOG4108IJ6	ABC transporter
D5400_20155	ENOG4105ZGE	Toxic component of a toxin-antitoxin (TA) module. A
D5400_20160	ENOG4105VJK	Transcription factor
D5400_20195	ENOG4108JJB	ABC transporter
D5400_20200	ENOG4107ZYJ	bioY protein
D5400_20215	ENOG4105C7K	acetolactate synthase
D5400_20220	ENOG4108S8N	class II Aldolase
D5400_20230	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_20240	ENOG4107BVJ	4,5-dihydroxyphthalate decarboxylase
D5400_20305	ENOG4107HP6	Transcriptional regulator
D5400_20310	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
D5400_20320	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D5400_20325	ENOG4107QSA	Oxaloacetate decarboxylase
D5400_20330	ENOG4105CH5	extracellular solute-binding protein, family 7
D5400_20340	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5400_20345	ENOG4108KEZ	Dehydrogenase
D5400_20350	ENOG4108UAU	isochorismatase
D5400_20365	ENOG4108JNI	Alpha beta hydrolase
D5400_20370	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
D5400_20375	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
D5400_20385	ENOG4105VQD	rieske 2fe-2S domain-containing protein
D5400_20395	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
D5400_20420	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
D5400_20435	ENOG4107HP6	Transcriptional regulator
D5400_20445	ENOG4108MVM	Transposase
D5400_20555	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
D5400_20560	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
D5400_20570	ENOG4108UVJ	appr-1-p processing domain protein
D5400_20610	ENOG4105CHH	sulfate transporter
D5400_20625	ENOG4105EXC	Acyl-transferase
D5400_20655	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
D5400_20705	ENOG4105DR5	peptidase
D5400_20710	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
D5400_20715	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D5400_20725	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
D5400_20730	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
D5400_20735	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
D5400_20740	ENOG4105CFH	Aspartokinase
D5400_20745	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D5400_20760	ENOG4105VW4	glutaredoxin 3
D5400_20765	ENOG4105MJ2	Competence protein
D5400_20785	ENOG4105M6F	mutator MutT protein
D5400_20795	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
D5400_20805	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
D5400_20820	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D5400_20825	ENOG4105BZU	Histidine kinase
D5400_20840	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
D5400_20855	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
D5400_20865	ENOG4107U9T	Pfam:Ribonuclease_BN
D5400_20870	ENOG4105E1F	short-chain dehydrogenase reductase
D5400_20890	ENOG4105BZJ	Electron transfer flavoprotein
D5400_20895	ENOG4105C10	Electron transfer flavoprotein
D5400_20900	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D5400_20905	ENOG4107ZT5	Thiol disulfide interchange protein
D5400_20910	ENOG4105CH7	arginosuccinase
D5400_20920	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
D5400_20925	ENOG4105BZU	Histidine kinase
D5400_20940	ENOG4105BZU	Histidine kinase
D5400_20945	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
D5400_20955	ENOG4105CAK	Cell division ATP-binding protein ftsE
D5400_20990	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D5400_20995	ENOG4105DWV	Homoserine O-trans-acetylase
D5400_21000	ENOG4105DWV	Homoserine O-trans-acetylase
D5400_21015	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
D5400_21025	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
D5400_21045	ENOG4105KDC	50s ribosomal protein l28
D5400_21050	ENOG4105EX9	Membrane
D5400_21080	ENOG4108JU6	CBS domain protein
D5400_21085	ENOG4105D49	3-dehydroquinate synthase
D5400_21090	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
D5400_21100	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D5400_21105	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
D5400_21125	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D5400_21140	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D5400_21145	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
D5400_21155	ENOG4105D3R	alkyl hydroperoxide reductase
D5400_21165	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
D5400_21175	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
D5400_21180	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
D5400_21185	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
D5400_21190	ENOG4105E39	Enoyl-CoA hydratase
D5400_21195	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)