locus-tag	class	description
WYH_00003	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
WYH_00007	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
WYH_00010	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
WYH_00013	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
WYH_00022	ENOG41087YS	Phage shock protein A
WYH_00024	ENOG4105E51	psp operon transcriptional activator
WYH_00025	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
WYH_00027	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
WYH_00030	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
WYH_00031	ENOG4107104	thymidine kinase
WYH_00033	ENOG4108Z4T	Peptidase M50
WYH_00034	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
WYH_00035	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
WYH_00036	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
WYH_00039	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
WYH_00041	ENOG4108SC4	)-transporter
WYH_00042	ENOG4105D6J	arsenicaL-resistance protein
WYH_00045	ENOG4108ZG0	Ompa motb domain protein
WYH_00047	ENOG4105E3A	(ABC) transporter
WYH_00050	ENOG4105NI3	Protein of unknown function (DUF3237)
WYH_00051	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
WYH_00053	ENOG4105DVW	rieske (2Fe-2S)
WYH_00055	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
WYH_00056	ENOG4107SCA	Formamidase (EC 3.5.1.49)
WYH_00058	ENOG4105E2B	Taurine dioxygenase
WYH_00059	ENOG4105ECQ	AraC Family Transcriptional Regulator
WYH_00063	ENOG4105D3W	isochorismatase
WYH_00064	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
WYH_00066	ENOG4108IXY	short-chain dehydrogenase reductase
WYH_00067	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
WYH_00068	ENOG4105FG0	Nitroreductase
WYH_00074	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
WYH_00075	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
WYH_00076	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
WYH_00077	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
WYH_00078	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
WYH_00079	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
WYH_00080	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
WYH_00081	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
WYH_00082	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WYH_00083	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
WYH_00084	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
WYH_00085	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
WYH_00086	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
WYH_00087	ENOG41083MP	50s ribosomal protein l29
WYH_00088	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
WYH_00089	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
WYH_00090	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
WYH_00091	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WYH_00092	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
WYH_00093	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
WYH_00094	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
WYH_00095	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
WYH_00097	ENOG41084HQ	50S ribosomal protein L30
WYH_00098	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
WYH_00099	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
WYH_00100	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
WYH_00102	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WYH_00103	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
WYH_00104	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
WYH_00105	ENOG4108ZT0	50S ribosomal protein l17
WYH_00109	ENOG4105EN6	Membrane
WYH_00112	ENOG4107QN2	dihydrolipoyl dehydrogenase
WYH_00113	ENOG4105C7S	Dehydrogenase
WYH_00114	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
WYH_00115	ENOG4105VC4	domain protein
WYH_00116	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
WYH_00117	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
WYH_00122	ENOG41081HM	2'-5' rna ligase
WYH_00130	ENOG4105K6T	rare lipoprotein A
WYH_00131	ENOG4105CDH	Citrulline--aspartate ligase
WYH_00132	ENOG4107R73	Mate efflux family protein
WYH_00133	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
WYH_00134	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
WYH_00135	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
WYH_00136	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
WYH_00137	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
WYH_00142	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
WYH_00143	ENOG4105KVH	Transcriptional regulator
WYH_00144	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
WYH_00148	ENOG4107S78	Band 7 protein
WYH_00151	ENOG4108RRZ	Transcription elongation factor GreB
WYH_00152	ENOG4107SC1	transglycosylase
WYH_00153	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
WYH_00154	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
WYH_00160	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
WYH_00161	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
WYH_00163	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
WYH_00164	ENOG4105CK7	Sodium proline symporter
WYH_00165	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
WYH_00169	ENOG4105D05	Receptor
WYH_00184	ENOG4106H78	methyltransferase
WYH_00187	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
WYH_00188	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
WYH_00189	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
WYH_00190	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
WYH_00191	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
WYH_00192	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
WYH_00194	ENOG4105C83	adenylosuccinate lyase
WYH_00198	ENOG4105W5Q	DNA repair protein (RadC
WYH_00203	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
WYH_00204	ENOG4105VD1	ATP synthase subunit C
WYH_00205	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
WYH_00206	ENOG4108733	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
WYH_00207	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
WYH_00209	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
WYH_00210	ENOG4105CAT	Cytidine monophosphate kinase
WYH_00212	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
WYH_00215	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WYH_00216	ENOG4105K5M	30s ribosomal protein S16
WYH_00217	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
WYH_00222	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
WYH_00223	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
WYH_00226	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
WYH_00230	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
WYH_00231	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
WYH_00232	ENOG4105FYV	Amp nucleosidase
WYH_00233	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
WYH_00235	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
WYH_00236	ENOG4105DFU	Cell wall formation (By similarity)
WYH_00238	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
WYH_00240	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
WYH_00241	ENOG4105EQH	reductase
WYH_00242	ENOG4105BZU	Histidine kinase
WYH_00243	ENOG4105BZU	Histidine kinase
WYH_00244	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
WYH_00245	ENOG4105FAT	Acyl-transferase
WYH_00251	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WYH_00255	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
WYH_00258	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
WYH_00261	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
WYH_00263	ENOG4105CHR	reductase
WYH_00266	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
WYH_00267	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
WYH_00268	ENOG4105KPV	Transcriptional regulator
WYH_00272	ENOG4105NA0	Transcriptional regulator
WYH_00275	ENOG4105CGZ	zinc metallopeptidase
WYH_00279	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
WYH_00281	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
WYH_00282	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
WYH_00283	ENOG4105DQU	oxidoreductase, subunit beta
WYH_00285	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
WYH_00286	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
WYH_00288	ENOG4105PDP	Short chain dehydrogenase
WYH_00289	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
WYH_00293	ENOG4105D75	Capsular exopolysaccharide family
WYH_00296	ENOG4105DQ6	Transposase
WYH_00302	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
WYH_00310	ENOG4108KQ5	Integrase catalytic subunit
WYH_00316	ENOG4105H37	Glyoxalase Bleomycin resistance protein (Dioxygenase
WYH_00317	ENOG41061H0	Monooxygenase
WYH_00323	ENOG4105DNH	Major Facilitator
WYH_00327	ENOG4105FBW	Monooxygenase
WYH_00328	ENOG4105DNH	Major Facilitator
WYH_00330	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
WYH_00333	ENOG4107ZSV	Receptor
WYH_00340	ENOG41060NJ	transcriptional regulator
WYH_00345	ENOG4105EDQ	levansucrase EC 2.4.1.10
WYH_00346	ENOG4105EVU	fructokinase
WYH_00347	ENOG4107R0V	Pyruvate dehydrogenase
WYH_00348	ENOG4105CPP	Dehydrogenase, E1 component
WYH_00349	ENOG4107QSN	dihydrolipoamide acetyltransferase
WYH_00353	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
WYH_00356	ENOG4105CV1	Transketolase (EC 2.2.1.1)
WYH_00359	ENOG4105BZA	Phosphoglycerate kinase
WYH_00360	ENOG4105WYW	fructose-bisphosphate aldolase
WYH_00362	ENOG4106HMZ	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
WYH_00364	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
WYH_00365	ENOG4105ECY	inositol monophosphatase
WYH_00368	ENOG4105CH2	amidohydrolase
WYH_00371	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
WYH_00374	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
WYH_00375	ENOG4105C8J	)-transporter
WYH_00379	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
WYH_00381	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
WYH_00383	ENOG4105C8U	phosphate abc transporter
WYH_00385	ENOG4106MAR	Phosphate-selective porin O and P
WYH_00386	ENOG4105BZU	Histidine kinase
WYH_00389	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
WYH_00392	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
WYH_00393	ENOG4108YYC	ycei family
WYH_00394	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
WYH_00395	ENOG4108ZP8	Acetolactate synthase small subunit
WYH_00396	ENOG4105C7K	acetolactate synthase
WYH_00397	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
WYH_00398	ENOG4105EAC	phosphoserine phosphatase
WYH_00399	ENOG4105DHF	Membrane
WYH_00400	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
WYH_00401	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
WYH_00402	ENOG4105CTB	Polyprenyl synthetase
WYH_00403	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
WYH_00404	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
WYH_00405	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
WYH_00406	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
WYH_00407	ENOG4105DA5	(ABC) transporter
WYH_00408	ENOG4105E3A	(ABC) transporter
WYH_00410	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
WYH_00411	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
WYH_00414	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
WYH_00415	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
WYH_00416	ENOG4108YZG	isomerase
WYH_00419	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
WYH_00421	ENOG4105KTH	gatB Yqey
WYH_00425	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
WYH_00431	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
WYH_00432	ENOG4107SET	aldo keto reductase
WYH_00433	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
WYH_00434	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
WYH_00435	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
WYH_00438	ENOG4105DMF	Dehydrogenase
WYH_00439	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
WYH_00442	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
WYH_00443	ENOG4108ISG	Major Facilitator
WYH_00444	ENOG4107XBN	GntR Family Transcriptional Regulator
WYH_00445	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
WYH_00445	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
WYH_00448	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
WYH_00456	ENOG4105C7K	acetolactate synthase
WYH_00465	ENOG4105D05	Receptor
WYH_00477	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
WYH_00482	ENOG4105C3G	gtp-binding protein
WYH_00484	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
WYH_00485	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
WYH_00488	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
WYH_00489	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
WYH_00490	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
WYH_00492	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
WYH_00493	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
WYH_00494	ENOG4105CSU	acyl-Coa dehydrogenase
WYH_00498	ENOG4105E8G	Major facilitator Superfamily
WYH_00500	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
WYH_00502	ENOG4105EHZ	conserved protein UCP016719
WYH_00503	ENOG4105DC7	peptidase M24
WYH_00505	ENOG4108W2P	Methyl-accepting chemotaxis
WYH_00507	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
WYH_00509	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
WYH_00510	ENOG41082FP	UPF0102 protein
WYH_00511	ENOG4105D7Z	glutathione synthase
WYH_00512	ENOG4107T5V	SNARE associated Golgi
WYH_00513	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
WYH_00514	ENOG4105CSA	Coproporphyrinogen iii oxidase
WYH_00515	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
WYH_00516	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
WYH_00517	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
WYH_00518	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WYH_00522	ENOG4105CFG	Acts as a chaperone (By similarity)
WYH_00527	ENOG4105CSH	Transporter
WYH_00528	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
WYH_00530	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
WYH_00531	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
WYH_00538	ENOG4105CYC	Transferase
WYH_00541	ENOG4105CVE	Lytic murein transglycosylase
WYH_00542	ENOG4105K6T	rare lipoprotein A
WYH_00543	ENOG4105DZ1	carboxypeptidase
WYH_00544	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
WYH_00545	ENOG4107QRG	dna polymerase iii
WYH_00547	ENOG4105F8V	Hydrolase, tatD family
WYH_00548	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
WYH_00550	ENOG4105DXN	mazG family
WYH_00551	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
WYH_00552	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
WYH_00553	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
WYH_00554	ENOG4105ES5	Histidine kinase
WYH_00555	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
WYH_00556	ENOG4105CUX	Signal transduction histidine kinase
WYH_00558	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
WYH_00559	ENOG4107TH8	cina domain protein
WYH_00560	ENOG4108Z1B	Cyclase dehydrase
WYH_00561	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
WYH_00562	ENOG4108V9Q	carbonic anhydrase
WYH_00567	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
WYH_00569	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
WYH_00572	ENOG4105CNI	cell division protein FtsW
WYH_00585	ENOG4107ZVI	PhiRv2 prophage protein
WYH_00586	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
WYH_00588	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
WYH_00594	ENOG4108ZNX	Heat shock protein
WYH_00595	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
WYH_00597	ENOG4105CP7	Triose-phosphate isomerase
WYH_00599	ENOG4105CRQ	synthase (Component I)
WYH_00600	ENOG4105DDQ	anthranilate synthase
WYH_00601	ENOG4108I0Q	anthranilate phosphoribosyltransferase
WYH_00602	ENOG4105DK0	Indole-3-glycerol phosphate synthase
WYH_00604	ENOG4108Z7R	Chaperone CsaA
WYH_00605	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
WYH_00606	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
WYH_00607	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
WYH_00608	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
WYH_00609	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
WYH_00610	ENOG4105BZN	citrate synthase
WYH_00612	ENOG4105BZU	Histidine kinase
WYH_00619	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
WYH_00620	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
WYH_00621	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
WYH_00622	ENOG4105C8S	subunit m
WYH_00623	ENOG4105D65	subunit l
WYH_00624	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
WYH_00625	ENOG4105DF2	NADH dehydrogenase subunit j
WYH_00626	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
WYH_00627	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
WYH_00628	ENOG4108IEH	NADH dehydrogenase subunit g
WYH_00630	ENOG4107QIZ	NADH dehydrogenase
WYH_00632	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
WYH_00633	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
WYH_00634	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
WYH_00635	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
WYH_00636	ENOG4105CHU	acetyl-coa acetyltransferase
WYH_00640	ENOG41089UC	methyltransferase, type 11
WYH_00641	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
WYH_00642	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WYH_00643	ENOG4108JQC	penicillin-binding protein 1A
WYH_00644	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
WYH_00645	ENOG4105C03	ribonuclease
WYH_00647	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
WYH_00649	ENOG4105CPF	Cell wall formation (By similarity)
WYH_00651	ENOG4105E33	succinate dehydrogenase
WYH_00652	ENOG4105D6Z	AFG1 family ATPase
WYH_00670	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
WYH_00672	ENOG4105C01	Dihydroxy-acid dehydratase
WYH_00674	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
WYH_00675	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
WYH_00678	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
WYH_00679	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
WYH_00684	ENOG4105C0B	DNA polymerase III (alpha subunit)
WYH_00687	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
WYH_00688	ENOG4105D60	lipoprotein releasing system transmembrane protein
WYH_00689	ENOG4105CB5	ATP-dependent DNA helicase recG
WYH_00691	ENOG4108JA2	transcriptioN-repair coupling factor
WYH_00693	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
WYH_00699	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
WYH_00702	ENOG4107TK4	histidinol-phosphate phosphatase
WYH_00704	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
WYH_00706	ENOG4108S0S	Nucleotidyl transferase
WYH_00707	ENOG4105EHM	Aminoglycoside phosphotransferase
WYH_00708	ENOG4105K8N	protein family UPF0079, ATPase
WYH_00709	ENOG4105I8F	Histidine kinase
WYH_00710	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
WYH_00711	ENOG4105EHV	domain protein
WYH_00712	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
WYH_00713	ENOG4105EUJ	GTP cyclohydrolase i
WYH_00714	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
WYH_00717	ENOG4105M6F	mutator MutT protein
WYH_00720	ENOG4105ERG	peptidase m48, ste24p
WYH_00721	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
WYH_00722	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
WYH_00725	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
WYH_00730	ENOG4107QX3	carboxylase
WYH_00732	ENOG4105C1J	atp-dependent rna helicase
WYH_00735	ENOG4107QP8	phosphohexose isomerase
WYH_00736	ENOG4105C3F	Signal peptidase i
WYH_00738	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
WYH_00739	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
WYH_00742	ENOG4105C79	DNA protecting protein DprA
WYH_00743	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
WYH_00744	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
WYH_00745	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
WYH_00754	ENOG4105E3Q	saccharopine dehydrogenase
WYH_00757	ENOG4105BZP	glycoside hydrolase 15-related
WYH_00762	ENOG4105D9N	nucleoside
WYH_00771	ENOG4105CMI	transporter
WYH_00772	ENOG4105CJ1	ABC, transporter
WYH_00773	ENOG4105D0S	secretion protein (HlyD
WYH_00777	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
WYH_00779	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
WYH_00780	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
WYH_00790	ENOG4105C0D	helicase
WYH_00796	ENOG4105E4C	Lytic transglycosylase catalytic
WYH_00797	ENOG4105DFP	Integrase
WYH_00799	ENOG4105HHA	aminodeoxychorismate lyase
WYH_00800	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
WYH_00801	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
WYH_00802	ENOG4105C9M	aspartyl-trna synthetase
WYH_00803	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
WYH_00804	ENOG4105C5Q	Transcriptional regulator
WYH_00810	ENOG4105BZU	Histidine kinase
WYH_00811	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
WYH_00812	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
WYH_00813	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
WYH_00814	ENOG4107835	probably involved in intracellular septation (By similarity)
WYH_00816	ENOG4105DFH	Transport of potassium into the cell (By similarity)
WYH_00818	ENOG4105KWW	Biogenesis protein
WYH_00819	ENOG4107QX9	Thiol disulfide interChange protein
WYH_00820	ENOG4105DA4	cytochrome c-type biogenesis protein
WYH_00821	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
WYH_00823	ENOG41060IM	Heme exporter protein
WYH_00828	ENOG41082FS	50S ribosomal protein L31
WYH_00829	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
WYH_00832	ENOG4105DZP	Membrane-associated zinc metalloprotease
WYH_00835	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
WYH_00836	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
WYH_00837	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
WYH_00838	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
WYH_00839	ENOG4105CE9	30S ribosomal protein S2
WYH_00842	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
WYH_00843	ENOG4106CY5	excisionase
WYH_00856	ENOG4105DFP	Integrase
WYH_00858	ENOG4105C2N	RNA methyltransferase TrmH family group 3
WYH_00861	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
WYH_00863	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
WYH_00864	ENOG4107QMP	dna polymerase iii subunits gamma and tau
WYH_00866	ENOG4105CQ7	ATP-dependent helicase
WYH_00868	ENOG4105EAH	synthase
WYH_00869	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
WYH_00871	ENOG4105IFJ	Histidine kinase
WYH_00872	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
WYH_00875	ENOG4105C5H	ABC transporter
WYH_00877	ENOG4105JNK	Glycosyl transferase (Group 1
WYH_00878	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
WYH_00879	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
WYH_00883	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
WYH_00884	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
WYH_00885	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
WYH_00887	ENOG4105F7P	transcriptional regulator AsnC family
WYH_00888	ENOG4105BZU	Histidine kinase
WYH_00894	ENOG4105CK2	sodium dicarboxylate symporter
WYH_00898	ENOG4107S8C	mandelate racemase muconate lactonizing
WYH_00901	ENOG4105D05	Receptor
WYH_00903	ENOG4105ETE	Transcriptional regulator (LacI family
WYH_00906	ENOG4105R0I	Feruloyl esterase
WYH_00909	ENOG4108PGP	mmge prpd family protein
WYH_00917	ENOG41084X4	Acylphosphatase (EC 3.6.1.7)
WYH_00921	ENOG4105DK7	lysyl-tRNA synthetase
WYH_00926	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
WYH_00928	ENOG4105DVT	helicase
WYH_00930	ENOG4105WJX	transcriptional regulator MERR family
WYH_00931	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
WYH_00932	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
WYH_00933	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
WYH_00934	ENOG4105C5X	domain protein
WYH_00938	ENOG4105C5I	Dehydrogenase
WYH_00939	ENOG4105C8N	cysteinyl-tRNA synthetase
WYH_00940	ENOG4105VAW	lrga family
WYH_00941	ENOG41067MG	lrgb family
WYH_00944	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
WYH_00946	ENOG4105C25	Primosomal protein n'
WYH_00948	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
WYH_00950	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
WYH_00951	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
WYH_00952	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
WYH_00953	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
WYH_00954	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
WYH_00963	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
WYH_00968	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
WYH_00969	ENOG4105W8H	transhydrogenase (subunit alpha
WYH_00970	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
WYH_00975	ENOG4105CEC	DNA methylase N-4 N-6
WYH_00977	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
WYH_00982	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
WYH_00984	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
WYH_00985	ENOG4107RKG	DJ-1/PfpI family
WYH_00987	ENOG4105C3J	Cysteine desulfurase
WYH_00988	ENOG4107QI6	Cysteine desulfurase
WYH_00989	ENOG4105DHZ	alpha beta
WYH_00995	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
WYH_00996	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
WYH_00997	ENOG4105EB3	Histidine kinase
WYH_00999	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
WYH_01000	ENOG4108EQA	pts system
WYH_01002	ENOG4108RWN	rrna methyltransferase
WYH_01005	ENOG4105CKU	formyltetrahydrofolate synthetase
WYH_01006	ENOG4107S2Z	UPF0761 membrane protein
WYH_01008	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
WYH_01009	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
WYH_01010	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
WYH_01012	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
WYH_01013	ENOG4105BZ4	penicillin-binding protein
WYH_01016	ENOG4105CYM	Glutathione S-transferase
WYH_01017	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
WYH_01021	ENOG4105EUB	pirin domain protein
WYH_01024	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
WYH_01028	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
WYH_01029	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
WYH_01033	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
WYH_01034	ENOG4105CBX	hi0933 family
WYH_01036	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
WYH_01037	ENOG4108Z03	MAF-like protein
WYH_01041	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
WYH_01043	ENOG4105D4P	Coproporphyrinogen iii oxidase
WYH_01049	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
WYH_01050	ENOG4105D05	Receptor
WYH_01052	ENOG4107QPR	SAICAR synthetase
WYH_01053	ENOG4107RAN	Peptidase, M16
WYH_01054	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
WYH_01055	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
WYH_01058	ENOG4105W4C	monovalent cation H antiporter subunit F
WYH_01060	ENOG4107R4Z	monovalent cation h antiporter subunit d
WYH_01061	ENOG4108ZE9	Monovalent cation H antiporter subunit C
WYH_01062	ENOG4105D65	subunit l
WYH_01064	ENOG4105CY0	Metallo-Beta-Lactamase
WYH_01066	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
WYH_01069	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
WYH_01070	ENOG4105VN1	Heat shock protein
WYH_01076	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
WYH_01079	ENOG4105D05	Receptor
WYH_01081	ENOG4105BZU	Histidine kinase
WYH_01082	ENOG4105CNV	Aldolase
WYH_01083	ENOG4108Z0R	Transferase
WYH_01084	ENOG4105C0A	alcohol dehydrogenase
WYH_01085	ENOG4107RGD	Major Facilitator superfamily
WYH_01086	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
WYH_01089	ENOG4105C26	Dehydrogenase
WYH_01090	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
WYH_01091	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
WYH_01107	ENOG4105E3B	Multicopper oxidase
WYH_01108	ENOG4105VPX	protein, conserved in bacteria
WYH_01110	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
WYH_01111	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
WYH_01113	ENOG4105D7W	serine acetyltransferase
WYH_01114	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
WYH_01116	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
WYH_01117	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
WYH_01119	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
WYH_01122	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
WYH_01124	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
WYH_01125	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
WYH_01126	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
WYH_01128	ENOG4107QP3	malate synthase g
WYH_01129	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
WYH_01131	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
WYH_01134	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
WYH_01140	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
WYH_01143	ENOG4105DBI	uridine monophosphokinase
WYH_01145	ENOG4105DZG	Dehydrogenase
WYH_01151	ENOG4105DZG	Dehydrogenase
WYH_01157	ENOG4105DZG	Dehydrogenase
WYH_01160	ENOG4105NWN	ApaG protein
WYH_01161	ENOG410903D	sensor protein
WYH_01167	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
WYH_01168	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
WYH_01172	ENOG4105DX0	Hemolysin A
WYH_01174	ENOG4105CM2	brancheD-chain amino acid aminotransferase
WYH_01180	ENOG4105CHF	Glutathione S-transferase
WYH_01181	ENOG4105CYM	Glutathione S-transferase
WYH_01186	ENOG4108KQ5	Integrase catalytic subunit
WYH_01189	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
WYH_01192	ENOG4105C26	Dehydrogenase
WYH_01196	ENOG4105D2S	major facilitator superfamily
WYH_01200	ENOG4105CJ2	(LipO)protein
WYH_01201	ENOG4107E2E	PKHD-type hydroxylase
WYH_01202	ENOG4108ESX	Receptor
WYH_01207	ENOG4105CBG	Sulfatase
WYH_01208	ENOG4107ZSV	Receptor
WYH_01210	ENOG41067HS	methyltransferase
WYH_01211	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
WYH_01212	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
WYH_01213	ENOG4107RAN	Peptidase, M16
WYH_01214	ENOG41083MR	nifu domain-containing protein
WYH_01215	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
WYH_01216	ENOG41072GX	Peptidase M22 Glycoprotease
WYH_01217	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
WYH_01218	ENOG4108YXV	Transcriptional regulator
WYH_01219	ENOG41090R7	Ferric uptake
WYH_01221	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
WYH_01225	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
WYH_01226	ENOG4107RCQ	(CBS) domain
WYH_01230	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
WYH_01231	ENOG4105CJW	magnesium transporter
WYH_01236	ENOG4105E09	nadh pyrophosphatase
WYH_01239	ENOG4105CEN	a g-specific adenine glycosylase
WYH_01243	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
WYH_01244	ENOG4108Z4X	TRANSCRIPTIONal
WYH_01249	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
WYH_01256	ENOG4105C26	Dehydrogenase
WYH_01259	ENOG4105FR1	rard protein
WYH_01260	ENOG4105EKE	dihydroorotase
WYH_01262	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
WYH_01265	ENOG4105K46	50S ribosomal protein l27
WYH_01266	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
WYH_01268	ENOG4108ZAF	Molybdopterin
WYH_01270	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
WYH_01275	ENOG4105D98	threonine synthase
WYH_01278	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
WYH_01279	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
WYH_01281	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
WYH_01282	ENOG4105BZ9	Cytochrome C oxidase, subunit I
WYH_01284	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
WYH_01286	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
WYH_01287	ENOG4105C3F	Signal peptidase i
WYH_01288	ENOG4105C02	permease
WYH_01290	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
WYH_01291	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
WYH_01294	ENOG4105CH7	arginosuccinase
WYH_01295	ENOG4105K63	Thioredoxin
WYH_01306	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
WYH_01307	ENOG4108UJV	acyl-CoA thioesterase i
WYH_01308	ENOG4108I0Y	(ABC) transporter
WYH_01310	ENOG4105D05	Receptor
WYH_01311	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
WYH_01313	ENOG4105NTW	Transcriptional regulator
WYH_01314	ENOG4105D1H	recombination factor protein RarA
WYH_01319	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
WYH_01321	ENOG4105KHC	sulfurtransferase
WYH_01322	ENOG4105C28	cystathionine
WYH_01323	ENOG4105D64	Mechanosensitive ion channel
WYH_01324	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
WYH_01326	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
WYH_01328	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
WYH_01330	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
WYH_01331	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WYH_01334	ENOG4105HFZ	Membrane
WYH_01335	ENOG4105II7	pyrroline-5-carboxylate reductase
WYH_01338	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
WYH_01339	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
WYH_01340	ENOG4108UFP	Essential cell division protein (By similarity)
WYH_01341	ENOG4105CPF	Cell wall formation (By similarity)
WYH_01342	ENOG4105D4A	Cell wall formation (By similarity)
WYH_01343	ENOG4105DFU	Cell wall formation (By similarity)
WYH_01344	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
WYH_01346	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
WYH_01347	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
WYH_01352	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
WYH_01353	ENOG4107YUR	Cell division protein mraZ
WYH_01356	ENOG4105C6T	cysteine synthase
WYH_01360	ENOG4105KZX	Pterin carbinolamine dehydratase
WYH_01361	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
WYH_01362	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
WYH_01364	ENOG4107RDJ	Sulfotransferase
WYH_01367	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
WYH_01369	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
WYH_01371	ENOG4107SQ0	N-acetyl-gamma-glutamyl-phosphate reductase
WYH_01372	ENOG4108YZA	Nitrogen regulatory protein pii
WYH_01373	ENOG4105C5F	glutamine synthetase
WYH_01377	ENOG4105CFU	surface antigen
WYH_01378	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
WYH_01379	ENOG4105C7B	Threonine dehydratase
WYH_01380	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
WYH_01381	ENOG4105EFZ	amidohydrolase
WYH_01383	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
WYH_01384	ENOG41081BE	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
WYH_01385	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
WYH_01386	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
WYH_01387	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
WYH_01388	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
WYH_01391	ENOG4105C75	arginyL-tRNA synthetase
WYH_01393	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
WYH_01394	ENOG4105CUV	Homoserine Kinase
WYH_01395	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
WYH_01396	ENOG4105HFZ	Membrane
WYH_01397	ENOG4105C5Q	Transcriptional regulator
WYH_01401	ENOG4106YAV	Domain of unknown function (DUF1508)
WYH_01402	ENOG4105FC8	fad dependent oxidoreductase
WYH_01412	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
WYH_01414	ENOG4108KPZ	tonB-dependent Receptor
WYH_01415	ENOG4107RDJ	Sulfotransferase
WYH_01420	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
WYH_01422	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
WYH_01423	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
WYH_01427	ENOG41082CG	Protein CrcB homolog
WYH_01428	ENOG4105EI2	Pseudouridine synthase
WYH_01435	ENOG4105CY3	ABC transporter, permease
WYH_01436	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
WYH_01438	ENOG4107QJQ	Mate efflux family protein
WYH_01439	ENOG4108UXN	response regulator
WYH_01445	ENOG410802X	bacteriophage n4 adsorption protein b
WYH_01449	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
WYH_01451	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
WYH_01452	ENOG4105DNH	Major Facilitator
WYH_01454	ENOG4108ESX	Receptor
WYH_01455	ENOG4105PF9	Transcriptional regulator
WYH_01456	ENOG4105K56	Transcriptional regulator
WYH_01459	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
WYH_01460	ENOG4105C5H	ABC transporter
WYH_01461	ENOG4105BZU	Histidine kinase
WYH_01463	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
WYH_01464	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
WYH_01465	ENOG4105PGM	cation diffusion facilitator family transporter
WYH_01466	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
WYH_01472	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
WYH_01473	ENOG4108R1E	Serine threonine protein phosphatase 1
WYH_01477	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
WYH_01479	ENOG4108UQY	Iron-storage protein
WYH_01481	ENOG4105DHF	Membrane
WYH_01483	ENOG4107QJE	Chromosome Partitioning Protein
WYH_01486	ENOG4105CD3	dihydroorotase
WYH_01487	ENOG4105CXT	aspartate transcarbamylase
WYH_01488	ENOG4105D07	Signal peptide peptidase, SppA
WYH_01494	ENOG4105CEV	competence damage-inducible protein
WYH_01495	ENOG4105C7W	Xanthine dehydrogenase
WYH_01496	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
WYH_01497	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
WYH_01498	ENOG4105EIG	urea carboxylase-associated protein 1
WYH_01505	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
WYH_01506	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
WYH_01510	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
WYH_01511	ENOG4105D05	Receptor
WYH_01522	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
WYH_01532	ENOG4105EXU	Membrane
WYH_01536	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
WYH_01540	ENOG4108XHQ	(2Fe-2S)-binding domain protein
WYH_01541	ENOG4105MP9	class II Aldolase
WYH_01543	ENOG4108I5G	Major Facilitator superfamily
WYH_01544	ENOG4108WFR	AraC Family Transcriptional Regulator
WYH_01548	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
WYH_01550	ENOG4105CPQ	Dehydrogenase
WYH_01551	ENOG4105F4R	Transcriptional regulator mode
WYH_01552	ENOG41074H6	response regulator
WYH_01560	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
WYH_01561	ENOG4105CHM	Aminotransferase
WYH_01563	ENOG4105C01	Dihydroxy-acid dehydratase
WYH_01568	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
WYH_01577	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
WYH_01578	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
WYH_01580	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
WYH_01580	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
WYH_01581	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
WYH_01585	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
WYH_01586	ENOG4105E0C	molybdate abc transporter
WYH_01587	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
WYH_01588	ENOG410903D	sensor protein
WYH_01593	ENOG4105E2B	Taurine dioxygenase
WYH_01594	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
WYH_01596	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
WYH_01598	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
WYH_01600	ENOG4105DWF	phosphomethylpyrimidine kinase
WYH_01603	ENOG4105C72	UPF0176 protein
WYH_01604	ENOG4105C1J	atp-dependent rna helicase
WYH_01607	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
WYH_01608	ENOG4105G9V	cytochrome C
WYH_01609	ENOG4105CQC	Prephenate dehydratase
WYH_01612	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
WYH_01616	ENOG4105I4A	GCN5-related N-acetyltransferase
WYH_01624	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
WYH_01627	ENOG4108I0Z	Aconitate hydratase
WYH_01629	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
WYH_01630	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
WYH_01631	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
WYH_01633	ENOG4108JU3	Alkyl hydroperoxide reductase
WYH_01638	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
WYH_01639	ENOG4105CJR	Integral membrane protein (MviN
WYH_01640	ENOG4105C31	Tryptophanyl-tRNA synthetase
WYH_01642	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
WYH_01643	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
WYH_01645	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
WYH_01648	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
WYH_01649	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
WYH_01650	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
WYH_01652	ENOG4105D06	uba thif-type nad fad binding protein
WYH_01653	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
WYH_01657	ENOG4107QJT	sodium dicarboxylate symporter
WYH_01658	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
WYH_01659	ENOG4108TGY	Glutathione S-transferase
WYH_01663	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
WYH_01665	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
WYH_01666	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
WYH_01667	ENOG4105VG0	50S ribosomal protein l34
WYH_01669	ENOG4105C0P	Mg chelatase subunit ChlI
WYH_01670	ENOG4105DZG	Dehydrogenase
WYH_01672	ENOG4105BZ9	Cytochrome C oxidase, subunit I
WYH_01673	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
WYH_01677	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
WYH_01688	ENOG4108ZHJ	Organic hydroperoxide resistance protein
WYH_01689	ENOG4105K56	Transcriptional regulator
WYH_01695	ENOG4105JJR	Histidine kinase
WYH_01697	ENOG4105D64	Mechanosensitive ion channel
WYH_01698	ENOG4107RZC	phospholipase d
WYH_01701	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
WYH_01702	ENOG4105BZS	acriflavin resistance protein
WYH_01703	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
WYH_01704	ENOG4105CEP	NADH dehydrogenase
WYH_01710	ENOG4105C0P	Mg chelatase subunit ChlI
WYH_01713	ENOG4105YK5	50S ribosomal protein L36
WYH_01719	ENOG4107THD	Involved in phosphonate degradation (By similarity)
WYH_01721	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
WYH_01722	ENOG4105KG3	cytidine deaminase
WYH_01724	ENOG4108ZTZ	UPF0262 protein
WYH_01727	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
WYH_01728	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
WYH_01738	ENOG4105CIH	Imidazole acetol-phosphate transaminase
WYH_01739	ENOG4105HF0	Membrane
WYH_01741	ENOG4105DG6	mannose-6-phosphate isomerase
WYH_01750	ENOG4105BZ1	(ABC) transporter
WYH_01753	ENOG4105CKK	Glycosyl transferase, family 2
WYH_01754	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
WYH_01767	ENOG4105D3Q	Sugar transferase
WYH_01777	ENOG4108VCT	Sulfite exporter TauE/SafE
WYH_01778	ENOG4107QPB	Beta-lactamase domain protein
WYH_01780	ENOG4105D3R	alkyl hydroperoxide reductase
WYH_01781	ENOG41080HT	Transcriptional regulator, arsr family
WYH_01782	ENOG4105K63	Thioredoxin
WYH_01785	ENOG41082J7	Rhodanese domain protein
WYH_01786	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
WYH_01789	ENOG4108JJ8	(ABC) transporter
WYH_01790	ENOG4108JJ9	ABC, transporter
WYH_01791	ENOG4105C4M	(Ubiquinol oxidase) subunit I
WYH_01792	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
WYH_01794	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
WYH_01795	ENOG4105D05	Receptor
WYH_01798	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
WYH_01804	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
WYH_01805	ENOG4107TAE	Glycosyl transferase (Group 1
WYH_01806	ENOG4108I69	Glycosyl transferases group 1
WYH_01808	ENOG4107YJ4	chain length determinant protein
WYH_01809	ENOG4105WH1	Two component transcriptional regulator luxr family
WYH_01810	ENOG4107RUY	(E1 component), alpha subunit
WYH_01811	ENOG4105CPP	Dehydrogenase, E1 component
WYH_01815	ENOG4105EXC	Acyl-transferase
WYH_01819	ENOG4105CGN	Glycosyl transferase (Group 1
WYH_01821	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
WYH_01822	ENOG4105WH1	Two component transcriptional regulator luxr family
WYH_01823	ENOG4105D3Q	Sugar transferase
WYH_01826	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
WYH_01829	ENOG4105YA8	Transcriptional regulator
WYH_01831	ENOG4105BZS	acriflavin resistance protein
WYH_01832	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
WYH_01833	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
WYH_01837	ENOG4105CTK	cobaltochelatase, cobn subunit
WYH_01841	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
WYH_01844	ENOG4108W6C	Dehydrogenase
WYH_01846	ENOG4107ZSV	Receptor
WYH_01848	ENOG41061H0	Monooxygenase
WYH_01854	ENOG4105JHE	Major Facilitator Superfamily
WYH_01855	ENOG4105C26	Dehydrogenase
WYH_01861	ENOG4107RSM	transcriptional regulator
WYH_01862	ENOG4105E3J	oxidoreductase
WYH_01865	ENOG4107ZSV	Receptor
WYH_01867	ENOG4108R85	Short chain dehydrogenase
WYH_01869	ENOG4105FUY	alpha subunit
WYH_01870	ENOG410811B	TRANSCRIPTIONal
WYH_01881	ENOG4105CHU	acetyl-coa acetyltransferase
WYH_01882	ENOG4107QNJ	CoA-transferase subunit B
WYH_01884	ENOG4107HP6	Transcriptional regulator
WYH_01888	ENOG4105WH1	Two component transcriptional regulator luxr family
WYH_01891	ENOG4105DC8	reductase
WYH_01894	ENOG4108KQ5	Integrase catalytic subunit
WYH_01895	ENOG4105DFP	Integrase
WYH_01898	ENOG4105D8V	Glucose sorbosone dehydrogenase
WYH_01902	ENOG4105GAK	amidohydrolase 2
WYH_01904	ENOG4105JSC	dimethylmenaquinone methyltransferase
WYH_01906	ENOG4105KHM	amidohydrolase 2
WYH_01915	ENOG4105K5X	acetyltransferase
WYH_01919	ENOG4105CNM	Receptor
WYH_01922	ENOG4105C26	Dehydrogenase
WYH_01924	ENOG4105CHR	reductase
WYH_01927	ENOG4105E2B	Taurine dioxygenase
WYH_01929	ENOG4105CNQ	glycine cleavage T protein, aminomethyl transferase
WYH_01935	ENOG4107QWG	2-Nitropropane dioxygenase
WYH_01937	ENOG4105CFH	Aspartokinase
WYH_01938	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
WYH_01939	ENOG4105FFC	UPF0187 protein
WYH_01940	ENOG4105Q26	Siderophore-interacting protein
WYH_01941	ENOG4105KUZ	arsenate reductase
WYH_01943	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
WYH_01944	ENOG4105CDY	transcriptional regulatory protein
WYH_01946	ENOG4105K8R	UPF0145 protein
WYH_01947	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
WYH_01948	ENOG4105Y2X	UPF0335 protein
WYH_01950	ENOG4105CA9	Pyruvate kinase
WYH_01951	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
WYH_01959	ENOG4105C5Q	Transcriptional regulator
WYH_01973	ENOG4105VV5	Plasmid stabilization system
WYH_01989	ENOG4105E4C	Lytic transglycosylase catalytic
WYH_01992	ENOG4105E4C	Lytic transglycosylase catalytic
WYH_01995	ENOG4105E4C	Lytic transglycosylase catalytic
WYH_02009	ENOG4105KK4	UPF0060 membrane protein
WYH_02013	ENOG4107QR8	Thioredoxin
WYH_02015	ENOG41081FY	multiple antibiotic resistance (MarC)-related
WYH_02019	ENOG4105CAS	nag kinase
WYH_02020	ENOG4105CSR	polyphosphate kinase 2
WYH_02025	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
WYH_02030	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
WYH_02033	ENOG4108IYU	L-aspartate oxidase
WYH_02034	ENOG4105DA5	(ABC) transporter
WYH_02042	ENOG4105CC0	LysR family Transcriptional regulator
WYH_02047	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
WYH_02050	ENOG4107QX3	carboxylase
WYH_02052	ENOG4105C1G	acyl-Coa dehydrogenase
WYH_02054	ENOG4108IJ8	ABC transporter
WYH_02057	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
WYH_02058	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
WYH_02061	ENOG4105DFA	alanine racemase domain protein
WYH_02063	ENOG4105CNU	cell division protein FtsK
WYH_02065	ENOG4107ZSV	Receptor
WYH_02070	ENOG4105DCF	alanine dehydrogenase
WYH_02071	ENOG4105BZU	Histidine kinase
WYH_02077	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
WYH_02078	ENOG4105JJR	Histidine kinase
WYH_02080	ENOG4105D7A	ATP-binding protein
WYH_02082	ENOG4105CHM	Aminotransferase
WYH_02084	ENOG4108YZN	class I peptide chain release factor
WYH_02085	ENOG4105W0E	50S ribosomal protein L33
WYH_02088	ENOG4107QJN	gtp cyclohydrolase ii
WYH_02093	ENOG4105C9U	ATP-dependent DNA helicase RecQ
WYH_02096	ENOG4105MIR	Phenylalanine 4-monooxygenase
WYH_02098	ENOG4105C9K	Endothelin-converting enzyme 1
WYH_02099	ENOG4105BZ1	(ABC) transporter
WYH_02111	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
WYH_02115	ENOG4105C22	threonyL-tRNA synthetase
WYH_02117	ENOG4105C26	Dehydrogenase
WYH_02118	ENOG4105DWY	Agmatine deiminase
WYH_02120	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
WYH_02121	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WYH_02122	ENOG4105ED9	Protein of unknown function (DUF455)
WYH_02123	ENOG4105DR5	peptidase
WYH_02128	ENOG4105CHR	reductase
WYH_02131	ENOG4105C8T	Leucyl-tRNA synthetase
WYH_02136	ENOG4105DEN	Luciferase family
WYH_02137	ENOG4105C7I	Dehydrogenase
WYH_02139	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
WYH_02140	ENOG4108IUX	(ABC) transporter
WYH_02142	ENOG4105E0X	reductase
WYH_02145	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
WYH_02148	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
WYH_02150	ENOG4105Q56	cytochrome P450
WYH_02152	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
WYH_02155	ENOG4105KSC	Transcriptional regulator, TraR DksA family
WYH_02160	ENOG4105FQP	Beta-lactamase
WYH_02161	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
WYH_02163	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
WYH_02167	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
WYH_02168	ENOG4105FDP	GntR family transcriptional regulator
WYH_02169	ENOG4105DUX	Transporter
WYH_02170	ENOG4105CI2	imidazolone-5-propionate hydrolase
WYH_02172	ENOG4108V1T	peptidylprolyl cis-trans isomerase
WYH_02173	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
WYH_02175	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
WYH_02179	ENOG4105DJV	ribulose-phosphate 3-epimerase
WYH_02183	ENOG4105CH2	amidohydrolase
WYH_02186	ENOG4107RNH	Outer membrane receptor FepA
WYH_02189	ENOG4106Z5D	Glycoside Hydrolase Family 43
WYH_02193	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
WYH_02194	ENOG4105C93	Xylose Isomerase
WYH_02195	ENOG4105CMG	Carbohydrate kinase
WYH_02196	ENOG4105DT9	hydrolase family 43
WYH_02197	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
WYH_02199	ENOG4105EMF	GntR family transcriptional regulator
WYH_02209	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
WYH_02211	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
WYH_02212	ENOG4105ETE	Transcriptional regulator (LacI family
WYH_02217	ENOG4105DSG	hydrolase family 43
WYH_02219	ENOG4105C01	Dihydroxy-acid dehydratase
WYH_02221	ENOG4105BZU	Histidine kinase
WYH_02224	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
WYH_02235	ENOG4105D0M	Protease HtpX homolog
WYH_02237	ENOG4108HRK	Histidine kinase
WYH_02238	ENOG4105DY9	regulatoR
WYH_02239	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
WYH_02242	ENOG4108Z6B	deaminase
WYH_02243	ENOG4105KDC	50s ribosomal protein l28
WYH_02247	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
WYH_02248	ENOG4105C12	Phosphoribosylglycinamide synthetase
WYH_02253	ENOG4108Z4V	iron-sulfur cluster assembly
WYH_02255	ENOG4105VG1	fes assembly suf system protein
WYH_02256	ENOG4105C9B	Cysteine desulfurase
WYH_02257	ENOG4105JRK	feS assembly protein SufD
WYH_02262	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
WYH_02263	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
WYH_02264	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
WYH_02267	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
WYH_02269	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
WYH_02271	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
WYH_02272	ENOG4108UJD	30S ribosomal protein S9
WYH_02279	ENOG4108NEV	two component transcriptional regulator, LytTR family
WYH_02280	ENOG4108HRK	Histidine kinase
WYH_02281	ENOG4107GFK	fumarate
WYH_02287	ENOG41080XP	Cbs domain
WYH_02288	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
WYH_02293	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
WYH_02294	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
WYH_02295	ENOG4107RZZ	dna polymerase iii epsilon subunit
WYH_02296	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
WYH_02297	ENOG4105E2X	shikimate dehydrogenase
WYH_02298	ENOG4108UHJ	MAF-like protein
WYH_02299	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
WYH_02300	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
WYH_02301	ENOG4108YXA	Membrane
WYH_02302	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
WYH_02305	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
WYH_02306	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
WYH_02307	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
WYH_02308	ENOG4107QJE	Chromosome Partitioning Protein
WYH_02309	ENOG4105FA0	parb-like partition protein
WYH_02314	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
WYH_02317	ENOG4108VJ1	Transcriptional regulator (CarD family
WYH_02318	ENOG4108Z4U	Ferredoxin
WYH_02319	ENOG4105CB5	ATP-dependent DNA helicase recG
WYH_02320	ENOG4105DR5	peptidase
WYH_02321	ENOG4105D52	delta-aminolevulinic acid dehydratase
WYH_02323	ENOG4108Z0R	Transferase
WYH_02324	ENOG410856B	UPF0235 protein
WYH_02325	ENOG4105CHH	sulfate transporter
WYH_02326	ENOG4107T0X	DNA ligase
WYH_02331	ENOG4105DQ4	alcohol dehydrogenase
WYH_02334	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
WYH_02337	ENOG4105DR5	peptidase
WYH_02338	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
WYH_02339	ENOG4105CPC	Aldo Keto reductase
WYH_02340	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
WYH_02342	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
WYH_02344	ENOG4105CN1	protease
WYH_02350	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
WYH_02351	ENOG4107U9T	Pfam:Ribonuclease_BN
WYH_02352	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
WYH_02353	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
WYH_02355	ENOG4105JAB	phenazine biosynthesis protein, phzf family
WYH_02358	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
WYH_02362	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
WYH_02364	ENOG4106BRA	Membrane
WYH_02367	ENOG4105C10	Electron transfer flavoprotein
WYH_02368	ENOG4105BZJ	Electron transfer flavoprotein
WYH_02369	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
WYH_02370	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
WYH_02371	ENOG4108ZG0	Ompa motb domain protein
WYH_02374	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
WYH_02376	ENOG4105DTN	riboflavin biosynthesis protein ribF
WYH_02378	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
WYH_02379	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
WYH_02380	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
WYH_02389	ENOG4105CD8	aminopeptidase N
WYH_02390	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
WYH_02391	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
WYH_02392	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
WYH_02393	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
WYH_02394	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
WYH_02396	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
WYH_02399	ENOG4105CA0	peroxidase
WYH_02400	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
WYH_02403	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
WYH_02405	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
WYH_02409	ENOG4107QRT	dEAD DEAH box helicase
WYH_02415	ENOG4105D6E	homoserine dehydrogenase
WYH_02416	ENOG4105CBT	Fructose-1,6-bisphosphatase
WYH_02421	ENOG41082BR	50S ribosomal protein L35
WYH_02422	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
WYH_02424	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
WYH_02425	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
WYH_02426	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
WYH_02429	ENOG4108YZA	Nitrogen regulatory protein pii
WYH_02430	ENOG4105BZU	Histidine kinase
WYH_02431	ENOG4105BZU	Histidine kinase
WYH_02432	ENOG4108YZA	Nitrogen regulatory protein pii
WYH_02435	ENOG4107S76	domain protein
WYH_02436	ENOG4105EE5	Membrane protein terC
WYH_02438	ENOG4105C8Y	Acetylornithine aminotransferase
WYH_02439	ENOG4105DBV	ornithine carbamoyltransferase
WYH_02440	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
WYH_02442	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
WYH_02443	ENOG4105D2S	major facilitator superfamily
WYH_02456	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
WYH_02458	ENOG4108UXN	response regulator
WYH_02464	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WYH_02468	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
WYH_02471	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
WYH_02472	ENOG4108WBT	adenosyltransferase
WYH_02474	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
WYH_02476	ENOG4105C6K	Malic enzyme
WYH_02497	ENOG4105PGM	cation diffusion facilitator family transporter
WYH_02509	ENOG4107SJW	iron permease, FTR1
WYH_02512	ENOG4105CJ1	ABC, transporter
WYH_02513	ENOG4107QWP	ABC-2 type transporter
WYH_02514	ENOG4107QWP	ABC-2 type transporter
WYH_02515	ENOG4105CSR	polyphosphate kinase 2
WYH_02518	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
WYH_02519	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
WYH_02520	ENOG4105CY0	Metallo-Beta-Lactamase
WYH_02523	ENOG4105CSU	acyl-Coa dehydrogenase
WYH_02524	ENOG4105CSU	acyl-Coa dehydrogenase
WYH_02525	ENOG4105C59	p-type ATPase
WYH_02527	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
WYH_02528	ENOG4105DAA	L-lactate
WYH_02529	ENOG4107RWR	Sodium hydrogen exchanger
WYH_02531	ENOG4105C5I	Dehydrogenase
WYH_02533	ENOG4105E9Q	Acyl-transferase
WYH_02536	ENOG4105E2V	Glycosyltransferase 36
WYH_02543	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
WYH_02544	ENOG4105HFZ	Membrane
WYH_02546	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
WYH_02548	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
WYH_02551	ENOG4105BZA	Phosphoglycerate kinase
WYH_02552	ENOG4108KQ5	Integrase catalytic subunit
WYH_02556	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
WYH_02559	ENOG4105CAF	HipA N-terminal domain protein
WYH_02569	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
WYH_02572	ENOG4105VPX	protein, conserved in bacteria
WYH_02583	ENOG4105C5X	domain protein
WYH_02586	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
WYH_02587	ENOG4108IJF	Heavy metal efflux pump, CzcA
WYH_02589	ENOG4105E3B	Multicopper oxidase
WYH_02595	ENOG4108KQ5	Integrase catalytic subunit
WYH_02597	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
WYH_02599	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
WYH_02600	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
WYH_02601	ENOG4108IUZ	ABC transporter
WYH_02603	ENOG4105D8X	mechanosensitive ion channel
WYH_02604	ENOG4105F0N	pyrophosphate phospho-hydrolase
WYH_02607	ENOG4105CUT	histidyl-tRNA synthetase
WYH_02608	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
WYH_02609	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
WYH_02611	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
WYH_02612	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
WYH_02613	ENOG4105DHF	Membrane
WYH_02615	ENOG4107QNJ	CoA-transferase subunit B
WYH_02618	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
WYH_02620	ENOG4105C2M	dna polymerase I
WYH_02625	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
WYH_02626	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
WYH_02627	ENOG4107QI1	Mate efflux family protein
WYH_02629	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
WYH_02630	ENOG4108VZM	50s ribosomal protein L10
WYH_02631	ENOG4105VMP	Transcriptional regulator
WYH_02634	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
WYH_02635	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
WYH_02636	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
WYH_02639	ENOG4105DHP	deoxycytidine triphosphate deaminase
WYH_02640	ENOG4105C26	Dehydrogenase
WYH_02642	ENOG4105C7K	acetolactate synthase
WYH_02643	ENOG4105CBS	Chea signal transduction histidine kinase
WYH_02645	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
WYH_02646	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
WYH_02647	ENOG4105BZU	Histidine kinase
WYH_02649	ENOG4108W2P	Methyl-accepting chemotaxis
WYH_02651	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
WYH_02653	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
WYH_02654	ENOG4105C26	Dehydrogenase
WYH_02658	ENOG4105BZU	Histidine kinase
WYH_02659	ENOG4108ZXC	Two component transcriptional regulator, luxr family
WYH_02662	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
WYH_02664	ENOG4108ZNX	Heat shock protein
WYH_02665	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
WYH_02671	ENOG4105VN1	Heat shock protein
WYH_02672	ENOG4108ZNX	Heat shock protein
WYH_02674	ENOG4105DU1	integral membrane protein, terc
WYH_02681	ENOG4105VN1	Heat shock protein
WYH_02682	ENOG4108ZNX	Heat shock protein
WYH_02683	ENOG4107RZC	phospholipase d
WYH_02684	ENOG4105CS1	NAD(P)H quinone oxidoreductase
WYH_02686	ENOG4105C0H	protease
WYH_02687	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
WYH_02689	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
WYH_02693	ENOG4106NZI	LysR family Transcriptional regulator
WYH_02716	ENOG4105E4C	Lytic transglycosylase catalytic
WYH_02730	ENOG4105P0T	Usg family
WYH_02732	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
WYH_02733	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
WYH_02734	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
WYH_02736	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
WYH_02739	ENOG4105D0M	Protease HtpX homolog
WYH_02741	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
WYH_02745	ENOG4105FDF	Could be involved in DNA repair (By similarity)
WYH_02746	ENOG4105DQE	DNA ligase
WYH_02747	ENOG4105CUY	Mechanosensitive ion channel
WYH_02764	ENOG4105CAK	Cell division ATP-binding protein ftsE
WYH_02769	ENOG4105CIH	Imidazole acetol-phosphate transaminase
WYH_02771	ENOG4105DWV	Homoserine O-trans-acetylase
WYH_02772	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
WYH_02774	ENOG4108IEG	Formate dehydrogenase Alpha subunit
WYH_02778	ENOG4105C4W	S-formylglutathione hydrolase
WYH_02781	ENOG4107QPD	alcohol dehydrogenase
WYH_02782	ENOG4105D2S	major facilitator superfamily
WYH_02787	ENOG4105NI3	Protein of unknown function (DUF3237)
WYH_02789	ENOG4105FP9	thiamine pyrophosphate
WYH_02790	ENOG4105DNH	Major Facilitator
WYH_02791	ENOG4105ECR	NmrA family
WYH_02798	ENOG4105E0X	reductase
WYH_02799	ENOG4105BZ4	penicillin-binding protein
WYH_02801	ENOG4105EPW	hflc protein
WYH_02802	ENOG4107QJR	hflk protein
WYH_02804	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
WYH_02805	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
WYH_02807	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
WYH_02809	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
WYH_02813	ENOG4105KPV	Transcriptional regulator
WYH_02816	ENOG410635A	Membrane
WYH_02817	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
WYH_02820	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WYH_02821	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WYH_02822	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
WYH_02823	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
WYH_02824	ENOG4105BZS	acriflavin resistance protein
WYH_02825	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
WYH_02834	ENOG4105BZU	Histidine kinase
WYH_02840	ENOG4107RCI	amp-dependent synthetase and ligase
WYH_02844	ENOG4106ECF	Uncharacterized protein conserved in bacteria (DUF2155)
WYH_02845	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
WYH_02848	ENOG4105BZG	amino acid carrier protein
WYH_02849	ENOG41062BN	Preprotein translocase SecE subunit
WYH_02850	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
WYH_02856	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
WYH_02857	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
WYH_02859	ENOG4105CEV	competence damage-inducible protein
WYH_02860	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
WYH_02862	ENOG4105DAE	Methylenetetrahydrofolate reductase
WYH_02864	ENOG410800I	Aminomethyltransferase
WYH_02869	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
WYH_02871	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
WYH_02878	ENOG4108VHT	MarR family transcriptional regulator
WYH_02880	ENOG4107QNK	)-transporter
WYH_02894	ENOG4105ECQ	AraC Family Transcriptional Regulator
WYH_02897	ENOG4105C26	Dehydrogenase
WYH_02905	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
WYH_02906	ENOG4108EHY	type IV secretion system
WYH_02910	ENOG4105EJX	conjugal transfer ATPase
WYH_02913	ENOG4105E4C	Lytic transglycosylase catalytic
WYH_02917	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
WYH_02921	ENOG4108ESX	Receptor
WYH_02929	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
WYH_02930	ENOG4105E2V	Glycosyltransferase 36
WYH_02932	ENOG4105C5I	Dehydrogenase
WYH_02938	ENOG4105CGF	Aromatic amino acid aminotransferase
WYH_02942	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
WYH_02945	ENOG4108ZZ3	UPF0260 protein
WYH_02950	ENOG4105CE1	Ferrous iron transport protein b
WYH_02951	ENOG4108UUM	single-stranded DNA-binding protein
WYH_02956	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
WYH_02959	ENOG4105CHH	sulfate transporter
WYH_02962	ENOG4108JJ7	ABC transporter
WYH_02965	ENOG41090RK	glycosyl transferase
WYH_02973	ENOG4105C9Q	fumarate hydratase class II
WYH_02977	ENOG4105KT7	mgtC SapB transporter
WYH_02980	ENOG4105KJF	protein tyrosine phosphatase
WYH_02981	ENOG4105FGM	Fructosamine kinase
WYH_02983	ENOG4108RM3	Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can serve as a key regulator of the sulfate assimilation pathway by controlling the pools of PAP and PAPS in the cell. To a lesser extent, is also able to hydrolyze inositol 1-phosphate (I- 1-P), fructose 1,6-bisphosphate (FBP) (to fructose 6-phosphate (F- 6-P)) and AMP in vitro, but this might has no significance in vivo
WYH_02985	ENOG4105C11	sulfate adenylyltransferase), subunit 2
WYH_02986	ENOG4108UKI	Enoyl-CoA hydratase
WYH_02987	ENOG4105C1G	acyl-Coa dehydrogenase
WYH_02989	ENOG4105KME	endoribonuclease L-psp
WYH_02992	ENOG4105DJG	MaoC domain protein dehydratase
WYH_02994	ENOG4105CMT	Dihydroxyacetone kinase
WYH_02996	ENOG4107YBY	Hydrolase
WYH_02997	ENOG4105D2N	Aldolase
WYH_03000	ENOG4105DFP	Integrase
WYH_03002	ENOG4107S1Q	Phosphatase
WYH_03012	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
WYH_03015	ENOG4107RDB	Major Facilitator
WYH_03018	ENOG4108URH	decarboxylase
WYH_03021	ENOG4108VRQ	UPF0314 protein
WYH_03023	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
WYH_03029	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
WYH_03032	ENOG4108UPT	UPF0178 protein
WYH_03033	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
WYH_03041	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
WYH_03042	ENOG4108V1U	phospholipid-binding protein
WYH_03046	ENOG4105VZ8	Transcriptional regulator
WYH_03055	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
WYH_03057	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
WYH_03060	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
WYH_03062	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
WYH_03064	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
WYH_03065	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
WYH_03066	ENOG4105K59	histidine triad (HIT) protein
WYH_03067	ENOG4107YD3	Thioesterase
WYH_03068	ENOG4105E02	MotA TolQ exbB proton channel
WYH_03069	ENOG4105SG9	biopolymer transport protein, ExbD
WYH_03071	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
WYH_03072	ENOG4105KCK	Peptidoglycan-associated lipoprotein
WYH_03074	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
WYH_03075	ENOG4105C28	cystathionine
WYH_03076	ENOG4105C8P	)-transporter
WYH_03080	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
WYH_03090	ENOG4105D05	Receptor
WYH_03096	ENOG4108XFH	Transcriptional regulator
WYH_03097	ENOG4105HDK	L-asparaginase
WYH_03102	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
WYH_03103	ENOG4105E0F	Histidine kinase
WYH_03104	ENOG4107B2H	carbonic anhydrase
WYH_03120	ENOG4105EUB	pirin domain protein
WYH_03125	ENOG4105DHU	Bile acid
WYH_03126	ENOG4105BZU	Histidine kinase
WYH_03130	ENOG4105BZU	Histidine kinase
WYH_03131	ENOG4108ZXC	Two component transcriptional regulator, luxr family
WYH_03134	ENOG4105D00	flagellar biosynthetic protein flhB
WYH_03135	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
WYH_03136	ENOG4105VS8	Flagellar biosynthetic protein fliq
WYH_03137	ENOG4105CN7	Flagellar biosynthetic protein FliP
WYH_03139	ENOG4105DD5	Flagellar motor switch protein
WYH_03144	ENOG4108JIR	Flagellum-specific ATP synthase
WYH_03146	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
WYH_03147	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
WYH_03148	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
WYH_03149	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
WYH_03153	ENOG4105ER2	Ompa motb domain protein
WYH_03154	ENOG4107RD7	Flagellar Motor Protein, MotA
WYH_03155	ENOG4105DTJ	flagellar hook-associated protein
WYH_03156	ENOG4105E1Q	flagellar hook-associated protein
WYH_03158	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
WYH_03160	ENOG4105CGA	flagellar basal-body rod protein FlgG
WYH_03161	ENOG4108KPB	Flagellar basal-body rod protein FlgF
WYH_03162	ENOG4105CGA	flagellar basal-body rod protein FlgG
WYH_03163	ENOG4105W00	Flagellar hook capping protein
WYH_03166	ENOG4105E14	MotA TolQ exbB proton channel
WYH_03172	ENOG4105D7B	Flagellar biosynthesis protein flha
WYH_03173	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
WYH_03175	ENOG4107QWP	ABC-2 type transporter
WYH_03176	ENOG4107QWP	ABC-2 type transporter
WYH_03177	ENOG4105CJ1	ABC, transporter
WYH_03179	ENOG4107MVR	Transcriptional regulator
WYH_03180	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
WYH_03181	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
WYH_03182	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
WYH_03188	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
WYH_03197	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
WYH_03201	ENOG4105VC4	domain protein
WYH_03205	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
WYH_03209	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
WYH_03212	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
WYH_03219	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
WYH_03220	ENOG4105K56	Transcriptional regulator
WYH_03221	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
WYH_03222	ENOG4105CD5	CoA-binding domain protein
WYH_03225	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
WYH_03226	ENOG4105C1G	acyl-Coa dehydrogenase
WYH_03228	ENOG4105CE9	30S ribosomal protein S2
WYH_03232	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
WYH_03233	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
WYH_03234	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
WYH_03237	ENOG4105D0A	hydroxylase
WYH_03244	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
WYH_03253	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
WYH_03280	ENOG4107QPD	alcohol dehydrogenase
WYH_03284	ENOG4105C26	Dehydrogenase
WYH_03285	ENOG4105C26	Dehydrogenase
WYH_03286	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
WYH_03288	ENOG4106JGA	Chromosome (Plasmid) partitioning protein, ParB
WYH_03297	ENOG4105KCK	Peptidoglycan-associated lipoprotein
WYH_03301	ENOG4108RW8	Universal stress protein F
WYH_03302	ENOG4107R3N	Filamentation induced by cAMP protein fic
WYH_03312	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
WYH_03313	ENOG4107R37	Glutamate dehydrogenase
WYH_03314	ENOG4105JVC	membrAne
WYH_03315	ENOG410841Q	phosphoesterase PA-phosphatase related protein
WYH_03326	ENOG4105DZ2	Transcriptional regulator
WYH_03328	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
WYH_03330	ENOG4105D05	Receptor
WYH_03333	ENOG41073TP	transcriptional regulator
WYH_03334	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
WYH_03335	ENOG4105DDW	LysR family Transcriptional regulator
WYH_03336	ENOG4105C26	Dehydrogenase
WYH_03337	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
WYH_03343	ENOG4108R85	Short chain dehydrogenase
WYH_03344	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
WYH_03345	ENOG4105C10	Electron transfer flavoprotein
WYH_03346	ENOG4105BZJ	Electron transfer flavoprotein
WYH_03347	ENOG4105C1G	acyl-Coa dehydrogenase