locus-tag	class	description
AMC99_00001	COG0217	transcriptional regulatory protein
AMC99_00002	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AMC99_00003	COG1393	Belongs to the ArsC family
AMC99_00004	COG3201	nicotinamide mononucleotide transporter
AMC99_00006	COG0584	glycerophosphoryl diester phosphodiesterase
AMC99_00007	COG0590	tRNA wobble adenosine to inosine editing
AMC99_00008	COG2814	Major facilitator Superfamily
AMC99_00009	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMC99_00010	COG0527	aspartate kinase activity
AMC99_00013	COG2070	2-Nitropropane dioxygenase
AMC99_00020	COG0330	HflC and HflK could
AMC99_00024	COG0582	viral genome integration into host DNA
AMC99_00030	COG1475	DNA binding
AMC99_00032	COG1476	TRANSCRIPTIONal
AMC99_00035	COG0758	DNA mediated transformation
AMC99_00037	COG0758	DNA mediated transformation
AMC99_00042	COG4227	nucleotidyltransferase activity
AMC99_00046	COG0629	single-stranded DNA binding
AMC99_00056	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMC99_00071	COG0681	Belongs to the peptidase S26 family
AMC99_00100	COG2217	Heavy metal translocating P-type atpase
AMC99_00111	COG0745	RESPONSE REGULATOR receiver
AMC99_00116	COG0129	dihydroxy-acid dehydratase activity
AMC99_00119	COG1959	2 iron, 2 sulfur cluster binding
AMC99_00123	COG0288	reversible hydration of carbon dioxide
AMC99_00128	COG2223	nitrite transmembrane transporter activity
AMC99_00129	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AMC99_00130	COG1140	nitrate reductase beta subunit
AMC99_00131	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AMC99_00132	COG2181	nitrate reductase activity
AMC99_00133	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMC99_00134	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMC99_00137	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMC99_00138	COG0303	'Molybdopterin
AMC99_00140	COG0746	molybdenum cofactor guanylyltransferase activity
AMC99_00141	COG0259	pyridoxamine-phosphate oxidase activity
AMC99_00142	COG1960	acyl-CoA dehydrogenase activity
AMC99_00147	COG0798	PFAM Bile acid sodium symporter
AMC99_00150	COG0583	DNA-binding transcription factor activity
AMC99_00153	COG1960	acyl-CoA dehydrogenase activity
AMC99_00157	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AMC99_00158	COG3383	formate dehydrogenase (NAD+) activity
AMC99_00168	COG1132	(ABC) transporter
AMC99_00172	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMC99_00172	COG2755	lipolytic protein G-D-S-L family
AMC99_00179	COG0438	transferase activity, transferring glycosyl groups
AMC99_00180	COG3206	protein involved in exopolysaccharide biosynthesis
AMC99_00180	COG0489	protein tyrosine kinase activity
AMC99_00183	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AMC99_00184	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AMC99_00189	COG3932	Exopolysaccharide synthesis, ExoD
AMC99_00191	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMC99_00192	COG1136	(ABC) transporter
AMC99_00192	COG4591	ABC-type transport system involved in lipoprotein release permease component
AMC99_00199	COG0489	protein tyrosine kinase activity
AMC99_00200	COG1758	RNA polymerase activity
AMC99_00201	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMC99_00203	COG5328	Belongs to the UPF0262 family
AMC99_00205	COG0295	cytidine deaminase activity
AMC99_00206	COG2323	membrane
AMC99_00207	COG2866	Carboxypeptidase
AMC99_00210	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AMC99_00218	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AMC99_00219	COG0594	ribonuclease P activity
AMC99_00220	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AMC99_00221	COG0706	membrane insertase activity
AMC99_00222	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AMC99_00224	COG0625	glutathione transferase activity
AMC99_00227	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMC99_00228	COG1301	dicarboxylic acid transport
AMC99_00230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AMC99_00232	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMC99_00233	COG2267	carboxylic ester hydrolase activity
AMC99_00234	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMC99_00236	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMC99_00238	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AMC99_00239	COG0268	Binds directly to 16S ribosomal RNA
AMC99_00240	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMC99_00241	COG2226	methyltransferase
AMC99_00242	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMC99_00245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AMC99_00246	COG0756	dUTP diphosphatase activity
AMC99_00250	COG0180	Tryptophanyl-tRNA synthetase
AMC99_00251	COG0728	peptidoglycan biosynthetic process
AMC99_00252	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AMC99_00253	COG4395	Tim44
AMC99_00260	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AMC99_00262	COG0450	alkyl hydroperoxide reductase
AMC99_00263	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMC99_00264	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AMC99_00266	COG0632	four-way junction helicase activity
AMC99_00267	COG2255	four-way junction helicase activity
AMC99_00273	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AMC99_00277	COG2989	Protein conserved in bacteria
AMC99_00279	COG0123	including yeast histone deacetylase and acetoin utilization protein
AMC99_00280	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AMC99_00284	COG0668	transmembrane transport
AMC99_00286	COG2367	Beta-lactamase
AMC99_00287	COG0454	-acetyltransferase
AMC99_00291	COG0714	Associated with various cellular activities
AMC99_00294	COG0077	Prephenate dehydratase
AMC99_00296	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AMC99_00297	COG0248	Ppx GppA phosphatase
AMC99_00303	COG3813	Protein conserved in bacteria
AMC99_00304	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMC99_00306	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AMC99_00310	COG3920	Histidine kinase
AMC99_00311	COG0784	Response regulator, receiver
AMC99_00320	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AMC99_00322	COG3243	poly(R)-hydroxyalkanoic acid synthase
AMC99_00323	COG0436	Aminotransferase
AMC99_00327	COG0745	RESPONSE REGULATOR receiver
AMC99_00328	COG1024	Enoyl-CoA hydratase
AMC99_00335	COG0646	methionine synthase
AMC99_00335	COG1410	methionine synthase
AMC99_00337	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMC99_00338	COG0509	glycine decarboxylation via glycine cleavage system
AMC99_00339	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMC99_00340	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMC99_00342	COG1024	Enoyl-CoA hydratase
AMC99_00343	COG1024	Enoyl-CoA hydratase
AMC99_00344	COG0346	lactoylglutathione lyase activity
AMC99_00347	COG0251	oxidation-reduction process
AMC99_00349	COG1609	Transcriptional regulator
AMC99_00350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMC99_00360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMC99_00363	COG1960	acyl-CoA dehydrogenase activity
AMC99_00364	COG1960	acyl-CoA dehydrogenase activity
AMC99_00367	COG0783	Belongs to the Dps family
AMC99_00369	COG0494	nUDIX hydrolase
AMC99_00387	COG2070	2-Nitropropane dioxygenase
AMC99_00391	COG1309	transcriptional regulator
AMC99_00392	COG2072	flavoprotein involved in K transport
AMC99_00394	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AMC99_00400	COG3040	lipid binding
AMC99_00401	COG1278	Cold shock
AMC99_00404	COG3384	dioxygenase
AMC99_00406	COG2824	Alkylphosphonate utilization operon protein PhnA
AMC99_00418	COG2171	N-acyltransferase activity
AMC99_00421	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AMC99_00422	COG1960	acyl-CoA dehydrogenase activity
AMC99_00423	COG2211	Major facilitator Superfamily
AMC99_00424	COG1960	acyl-CoA dehydrogenase activity
AMC99_00425	COG1960	acyl-CoA dehydrogenase activity
AMC99_00427	COG0194	GDP metabolic process
AMC99_00430	COG0131	Imidazoleglycerol-phosphate dehydratase
AMC99_00431	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AMC99_00432	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AMC99_00434	COG0107	imidazoleglycerol-phosphate synthase activity
AMC99_00435	COG0140	phosphoribosyl-ATP diphosphatase activity
AMC99_00437	COG0824	Thioesterase
AMC99_00441	COG0823	Involved in the tonB-independent uptake of proteins
AMC99_00442	COG2885	chlorophyll binding
AMC99_00448	COG0471	metal ion transport
AMC99_00449	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AMC99_00451	COG0408	coproporphyrinogen oxidase activity
AMC99_00464	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_00465	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_00471	COG2272	Belongs to the type-B carboxylesterase lipase family
AMC99_00472	COG4771	TonB-dependent receptor
AMC99_00473	COG4771	TonB-dependent receptor
AMC99_00474	COG2272	Belongs to the type-B carboxylesterase lipase family
AMC99_00475	COG2814	Major facilitator Superfamily
AMC99_00476	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMC99_00476	COG1024	Enoyl-CoA hydratase
AMC99_00478	COG0183	Belongs to the thiolase family
AMC99_00479	COG0318	PFAM AMP-dependent synthetase and ligase
AMC99_00480	COG1309	transcriptional regulator
AMC99_00483	COG1960	acyl-CoA dehydrogenase activity
AMC99_00484	COG2211	Major facilitator Superfamily
AMC99_00485	COG1960	acyl-CoA dehydrogenase activity
AMC99_00489	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_00491	COG2272	Belongs to the type-B carboxylesterase lipase family
AMC99_00497	COG3507	Belongs to the glycosyl hydrolase 43 family
AMC99_00498	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMC99_00501	COG2721	sulfolactate sulfo-lyase activity
AMC99_00502	COG1904	glucuronate isomerase
AMC99_00503	COG0246	Mannitol dehydrogenase
AMC99_00508	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMC99_00510	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMC99_00511	COG2205	protein histidine kinase activity
AMC99_00511	COG0784	Response regulator, receiver
AMC99_00513	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMC99_00519	COG0424	maF-like protein
AMC99_00520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMC99_00524	COG2081	HI0933 family
AMC99_00525	COG2197	response regulator
AMC99_00526	COG0322	excinuclease ABC activity
AMC99_00528	COG0513	Belongs to the DEAD box helicase family
AMC99_00533	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AMC99_00535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMC99_00536	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AMC99_00537	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AMC99_00540	COG1741	Belongs to the pirin family
AMC99_00541	COG0271	Belongs to the BolA IbaG family
AMC99_00546	COG5507	3-demethylubiquinone-9 3-methyltransferase
AMC99_00557	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AMC99_00559	COG0628	permease
AMC99_00560	COG0681	Belongs to the peptidase S26 family
AMC99_00561	COG0736	holo-[acyl-carrier-protein] synthase activity
AMC99_00562	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AMC99_00563	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMC99_00564	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMC99_00565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMC99_00567	COG0109	protoheme IX farnesyltransferase activity
AMC99_00569	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AMC99_00577	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMC99_00579	COG0314	molybdopterin synthase activity
AMC99_00580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMC99_00582	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AMC99_00583	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AMC99_00589	COG0418	dihydroorotase activity
AMC99_00593	COG1012	belongs to the aldehyde dehydrogenase family
AMC99_00594	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AMC99_00598	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMC99_00600	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AMC99_00604	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AMC99_00607	COG0789	Transcriptional regulator
AMC99_00611	COG1522	sequence-specific DNA binding
AMC99_00620	COG1278	Cold shock
AMC99_00623	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMC99_00632	COG1047	Peptidyl-prolyl cis-trans
AMC99_00634	COG0640	Transcriptional regulator
AMC99_00636	COG3706	GGDEF domain
AMC99_00642	COG1522	sequence-specific DNA binding
AMC99_00646	COG0439	Biotin carboxylase
AMC99_00647	COG0511	ligase activity, forming carbon-carbon bonds
AMC99_00648	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMC99_00653	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMC99_00654	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMC99_00658	COG1573	uracil-dna glycosylase
AMC99_00662	COG0745	RESPONSE REGULATOR receiver
AMC99_00663	COG2205	protein histidine kinase activity
AMC99_00665	COG1605	Chorismate mutase
AMC99_00665	COG0287	Prephenate dehydrogenase
AMC99_00666	COG0142	geranyltranstransferase activity
AMC99_00667	COG0667	Aldo Keto reductase
AMC99_00668	COG1643	Atp-dependent helicase
AMC99_00672	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AMC99_00675	COG0776	regulation of translation
AMC99_00677	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMC99_00681	COG0688	phosphatidylethanolamine metabolic process
AMC99_00682	COG1183	phosphatidylcholine synthase activity
AMC99_00684	COG0052	Belongs to the universal ribosomal protein uS2 family
AMC99_00685	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AMC99_00686	COG0528	UMP kinase activity
AMC99_00687	COG0233	cytoplasmic translational termination
AMC99_00688	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AMC99_00689	COG0575	Belongs to the CDS family
AMC99_00690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AMC99_00691	COG0750	zinc metalloprotease
AMC99_00694	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMC99_00695	COG0254	rRNA binding
AMC99_00701	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMC99_00703	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AMC99_00704	COG1138	Cytochrome C-type biogenesis protein
AMC99_00706	COG3088	subunit of a heme lyase
AMC99_00708	COG3158	transport of potassium into the cell
AMC99_00710	COG2917	probably involved in intracellular septation
AMC99_00711	COG0552	protein localization to endoplasmic reticulum
AMC99_00712	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMC99_00713	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AMC99_00714	COG5001	Diguanylate cyclase
AMC99_00714	COG3300	MHYT domain
AMC99_00719	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMC99_00722	COG0583	DNA-binding transcription factor activity
AMC99_00723	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AMC99_00724	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMC99_00725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMC99_00726	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMC99_00727	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AMC99_00734	COG2989	Protein conserved in bacteria
AMC99_00735	COG1435	thymidine kinase activity
AMC99_00736	COG1994	Peptidase M50
AMC99_00738	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AMC99_00739	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AMC99_00740	COG1185	polyribonucleotide nucleotidyltransferase activity
AMC99_00745	COG0842	Transport permease protein
AMC99_00749	COG1024	Enoyl-CoA hydratase
AMC99_00752	COG4771	TonB-dependent receptor
AMC99_00753	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_00759	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMC99_00763	COG3118	belongs to the thioredoxin family
AMC99_00765	COG0450	alkyl hydroperoxide reductase
AMC99_00772	COG0640	Transcriptional regulator
AMC99_00773	COG0509	glycine decarboxylation via glycine cleavage system
AMC99_00775	COG2048	Heterodisulfide reductase, subunit B
AMC99_00778	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMC99_00783	COG0095	Lipoate-protein ligase
AMC99_00786	COG0123	including yeast histone deacetylase and acetoin utilization protein
AMC99_00787	COG2210	Belongs to the sulfur carrier protein TusA family
AMC99_00788	COG0425	Belongs to the sulfur carrier protein TusA family
AMC99_00790	COG0243	molybdopterin cofactor binding
AMC99_00791	COG0437	4 iron, 4 sulfur cluster binding
AMC99_00792	COG3302	dmso reductase anchor subunit
AMC99_00793	COG0489	protein tyrosine kinase activity
AMC99_00795	COG0450	alkyl hydroperoxide reductase
AMC99_00796	COG1271	oxidase subunit
AMC99_00797	COG1294	oxidase, subunit
AMC99_00799	COG2030	dehydratase
AMC99_00801	COG0686	Belongs to the AlaDH PNT family
AMC99_00802	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AMC99_00804	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AMC99_00806	COG0625	glutathione transferase activity
AMC99_00812	COG2304	oxidoreductase activity
AMC99_00814	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AMC99_00815	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AMC99_00816	COG0181	hydroxymethylbilane synthase activity
AMC99_00819	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMC99_00820	COG4232	protein-disulfide reductase activity
AMC99_00822	COG0556	nucleotide-excision repair
AMC99_00824	COG2226	methyltransferase
AMC99_00824	COG0596	Alpha beta hydrolase
AMC99_00824	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMC99_00825	COG2308	Evidence 4 Homologs of previously reported genes of
AMC99_00831	COG0640	Transcriptional regulator
AMC99_00838	COG4771	TonB-dependent receptor
AMC99_00839	COG3152	Membrane
AMC99_00841	COG4181	ATPase activity
AMC99_00843	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AMC99_00852	COG1970	mechanosensitive ion channel activity
AMC99_00855	COG3724	N-succinylarginine dihydrolase activity
AMC99_00856	COG3138	arginine N-succinyltransferase
AMC99_00858	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AMC99_00860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMC99_00861	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AMC99_00862	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMC99_00863	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AMC99_00864	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMC99_00868	COG0105	UTP biosynthetic process
AMC99_00871	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AMC99_00872	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AMC99_00875	COG1045	serine acetyltransferase
AMC99_00877	COG1218	3'(2'),5'-bisphosphate nucleotidase
AMC99_00880	COG0175	sulfate reduction
AMC99_00881	COG1877	trehalose-phosphatase activity
AMC99_00882	COG3387	PFAM Glycoside hydrolase 15-related
AMC99_00883	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AMC99_00884	COG0745	RESPONSE REGULATOR receiver
AMC99_00886	COG0492	ferredoxin-NADP+ reductase activity
AMC99_00890	COG1748	Saccharopine dehydrogenase
AMC99_00897	COG2175	clavaminate synthase activity
AMC99_00899	COG0156	8-amino-7-oxononanoate synthase activity
AMC99_00900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AMC99_00901	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AMC99_00902	COG0758	DNA mediated transformation
AMC99_00904	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AMC99_00904	COG1754	DNA topoisomerase type I activity
AMC99_00909	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AMC99_00910	COG0571	ribonuclease III activity
AMC99_00911	COG0681	Belongs to the peptidase S26 family
AMC99_00912	COG0166	Belongs to the GPI family
AMC99_00915	COG0513	Belongs to the DEAD box helicase family
AMC99_00917	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMC99_00918	COG1396	sequence-specific DNA binding
AMC99_00918	COG3800	Transcriptional regulator
AMC99_00919	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMC99_00921	COG1024	Enoyl-CoA hydratase
AMC99_00924	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMC99_00927	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMC99_00929	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AMC99_00930	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMC99_00931	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AMC99_00934	COG4974	Belongs to the 'phage' integrase family
AMC99_00935	COG0825	malonyl-CoA metabolic process
AMC99_00939	COG0494	nUDIX hydrolase
AMC99_00943	COG0302	gtp cyclohydrolase
AMC99_00945	COG0678	peroxiredoxin activity
AMC99_00945	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AMC99_00946	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AMC99_00947	COG2205	protein histidine kinase activity
AMC99_00948	COG0802	atpase or kinase
AMC99_00949	COG3178	'Phosphotransferase
AMC99_00950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMC99_00952	COG1074	ATP-dependent DNA helicase activity
AMC99_00954	COG0483	inositol monophosphate 1-phosphatase activity
AMC99_00955	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AMC99_00958	COG0653	protein targeting
AMC99_00962	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMC99_00963	COG2203	Gaf domain
AMC99_00963	COG3706	GGDEF domain
AMC99_00963	COG5001	Diguanylate cyclase
AMC99_00963	COG4251	negative regulation of phosphorylation
AMC99_00964	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AMC99_00967	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AMC99_00968	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMC99_00970	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_00973	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AMC99_00979	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AMC99_00983	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AMC99_00984	COG0126	phosphoglycerate kinase activity
AMC99_00989	COG0352	thiamine-phosphate diphosphorylase activity
AMC99_00990	COG1376	ErfK ybiS ycfS ynhG family protein
AMC99_00991	COG4942	peptidase
AMC99_00993	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMC99_00995	COG0483	inositol monophosphate 1-phosphatase activity
AMC99_00997	COG1196	nuclear chromosome segregation
AMC99_00997	COG3264	Mechanosensitive ion channel
AMC99_00998	COG3273	potassium ion transport
AMC99_00998	COG0471	metal ion transport
AMC99_01002	COG1396	sequence-specific DNA binding
AMC99_01002	COG3800	Transcriptional regulator
AMC99_01004	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMC99_01006	COG2204	response regulator
AMC99_01008	COG0385	Bile acid
AMC99_01010	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AMC99_01011	COG0733	neurotransmitter:sodium symporter activity
AMC99_01014	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMC99_01017	COG1573	uracil-dna glycosylase
AMC99_01020	COG2814	Major facilitator Superfamily
AMC99_01021	COG0745	RESPONSE REGULATOR receiver
AMC99_01022	COG0704	Plays a role in the regulation of phosphate uptake
AMC99_01023	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMC99_01025	COG0573	inorganic phosphate transmembrane transporter activity
AMC99_01028	COG3746	phosphate-selective porin O and P
AMC99_01031	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AMC99_01031	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AMC99_01040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMC99_01042	COG0596	Alpha beta hydrolase
AMC99_01045	COG2353	YceI-like domain
AMC99_01046	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AMC99_01048	COG0028	Belongs to the TPP enzyme family
AMC99_01049	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMC99_01050	COG0560	Phosphoserine phosphatase
AMC99_01053	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMC99_01056	COG1722	exodeoxyribonuclease VII activity
AMC99_01057	COG0142	geranyltranstransferase activity
AMC99_01058	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AMC99_01059	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMC99_01060	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AMC99_01061	COG1131	(ABC) transporter
AMC99_01062	COG0842	Transport permease protein
AMC99_01064	COG0343	queuine tRNA-ribosyltransferase activity
AMC99_01068	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AMC99_01071	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMC99_01073	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMC99_01074	COG0698	ribose 5-phosphate isomerase
AMC99_01075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMC99_01076	COG0358	DNA primase activity
AMC99_01079	COG0505	Belongs to the CarA family
AMC99_01081	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMC99_01088	COG0148	phosphopyruvate hydratase activity
AMC99_01091	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMC99_01095	COG0772	Belongs to the SEDS family
AMC99_01100	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AMC99_01104	COG0012	GTP binding
AMC99_01105	COG4221	oxidoreductase activity
AMC99_01106	COG0193	aminoacyl-tRNA hydrolase activity
AMC99_01107	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AMC99_01113	COG0752	glycyl-tRNA synthetase alpha subunit
AMC99_01116	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMC99_01116	COG0574	Belongs to the PEP-utilizing enzyme family
AMC99_01119	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AMC99_01120	COG0789	Transcriptional regulator
AMC99_01121	COG1960	acyl-CoA dehydrogenase activity
AMC99_01127	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMC99_01129	COG3876	Protein conserved in bacteria
AMC99_01133	COG0840	transmembrane signaling receptor activity
AMC99_01134	COG0840	transmembrane signaling receptor activity
AMC99_01135	COG0840	transmembrane signaling receptor activity
AMC99_01136	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMC99_01141	COG0187	DNA topoisomerase II activity
AMC99_01143	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AMC99_01144	COG0792	nuclease activity
AMC99_01145	COG0189	ligase activity
AMC99_01146	COG0586	Pfam SNARE associated Golgi protein
AMC99_01147	COG4974	Belongs to the 'phage' integrase family
AMC99_01148	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMC99_01150	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AMC99_01151	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AMC99_01152	COG1420	regulation of RNA biosynthetic process
AMC99_01153	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMC99_01158	COG0443	Heat shock 70 kDa protein
AMC99_01159	COG0484	heat shock protein binding
AMC99_01161	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMC99_01166	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMC99_01168	COG0442	prolyl-tRNA aminoacylation
AMC99_01169	COG0557	exoribonuclease II activity
AMC99_01171	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMC99_01173	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMC99_01176	COG2951	lytic endotransglycosylase activity
AMC99_01177	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMC99_01178	COG1686	Belongs to the peptidase S11 family
AMC99_01179	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AMC99_01182	COG0084	hydrolase, TatD family'
AMC99_01183	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AMC99_01183	COG0321	lipoyl(octanoyl) transferase activity
AMC99_01185	COG3956	TIGRFAM MazG family protein
AMC99_01186	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AMC99_01187	COG1923	regulation of RNA biosynthetic process
AMC99_01188	COG2204	response regulator
AMC99_01190	COG2204	response regulator
AMC99_01191	COG3852	Histidine kinase
AMC99_01193	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AMC99_01193	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AMC99_01194	COG1546	Belongs to the CinA family
AMC99_01196	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMC99_01197	COG0288	reversible hydration of carbon dioxide
AMC99_01203	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AMC99_01209	COG0022	dehydrogenase e1 component
AMC99_01209	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMC99_01210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AMC99_01213	COG0668	transmembrane transport
AMC99_01214	COG2814	Major facilitator Superfamily
AMC99_01217	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMC99_01218	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AMC99_01219	COG0071	Belongs to the small heat shock protein (HSP20) family
AMC99_01220	COG0504	CTP synthase activity
AMC99_01222	COG0149	triose-phosphate isomerase activity
AMC99_01224	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMC99_01228	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMC99_01229	COG0134	indole-3-glycerol-phosphate synthase activity
AMC99_01230	COG0315	cyclic pyranopterin monophosphate synthase activity
AMC99_01231	COG0303	'Molybdopterin
AMC99_01232	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMC99_01233	COG2333	competence protein COMEC
AMC99_01233	COG0658	competence protein
AMC99_01234	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMC99_01235	COG0372	Belongs to the citrate synthase family
AMC99_01237	COG2205	protein histidine kinase activity
AMC99_01244	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AMC99_01246	COG1007	ATP synthesis coupled electron transport
AMC99_01249	COG0713	ATP synthesis coupled electron transport
AMC99_01251	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMC99_01252	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMC99_01253	COG1034	ATP synthesis coupled electron transport
AMC99_01255	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AMC99_01257	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AMC99_01258	COG0649	NAD binding
AMC99_01259	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMC99_01260	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMC99_01261	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMC99_01262	COG1012	belongs to the aldehyde dehydrogenase family
AMC99_01263	COG0183	Belongs to the thiolase family
AMC99_01268	COG0004	ammonium transporteR
AMC99_01274	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AMC99_01275	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMC99_01276	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMC99_01277	COG1530	ribonuclease E activity
AMC99_01278	COG2226	methyltransferase
AMC99_01283	COG2244	polysaccharide biosynthetic process
AMC99_01285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AMC99_01287	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AMC99_01290	COG0367	asparagine synthase
AMC99_01294	COG0726	polysaccharide deacetylase
AMC99_01295	COG3267	Type II secretory pathway component ExeA
AMC99_01295	COG3409	Peptidoglycan-binding domain 1 protein
AMC99_01307	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMC99_01308	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AMC99_01308	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMC99_01310	COG0129	dihydroxy-acid dehydratase activity
AMC99_01312	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AMC99_01316	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMC99_01322	COG0587	DNA-directed DNA polymerase activity
AMC99_01323	COG2311	Membrane
AMC99_01324	COG0386	Belongs to the glutathione peroxidase family
AMC99_01326	COG1136	(ABC) transporter
AMC99_01328	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AMC99_01329	COG4221	oxidoreductase activity
AMC99_01332	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMC99_01333	COG0415	Belongs to the DNA photolyase family
AMC99_01335	COG0671	phosphoesterase, PA-phosphatase related
AMC99_01336	COG1013	pyruvate-flavodoxin oxidoreductase activity
AMC99_01337	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AMC99_01337	COG0674	pyruvate-flavodoxin oxidoreductase activity
AMC99_01339	COG1051	belongs to the nudix hydrolase family
AMC99_01341	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMC99_01341	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMC99_01344	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_01345	COG2321	neutral zinc metallopeptidase
AMC99_01347	COG4452	Inner membrane protein CreD
AMC99_01349	COG3682	Transcriptional regulator
AMC99_01350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMC99_01354	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AMC99_01356	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_01357	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMC99_01358	COG2264	protein methyltransferase activity
AMC99_01359	COG1024	Enoyl-CoA hydratase
AMC99_01361	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMC99_01364	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMC99_01371	COG0481	GTPase activity
AMC99_01372	COG5001	Diguanylate cyclase
AMC99_01373	COG3300	MHYT domain
AMC99_01373	COG5001	Diguanylate cyclase
AMC99_01376	COG0493	'glutamate synthase
AMC99_01378	COG0596	Alpha beta hydrolase
AMC99_01380	COG1064	alcohol dehydrogenase
AMC99_01382	COG0592	DNA-directed DNA polymerase activity
AMC99_01385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AMC99_01386	COG1619	proteins homologs of microcin C7 resistance protein MccF
AMC99_01387	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMC99_01389	COG2354	Protein conserved in bacteria
AMC99_01390	COG0360	Binds together with S18 to 16S ribosomal RNA
AMC99_01391	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AMC99_01392	COG0359	binds to the 23S rRNA
AMC99_01394	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AMC99_01395	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_01396	COG3920	Histidine kinase
AMC99_01397	COG0189	ligase activity
AMC99_01398	COG4067	protein conserved in archaea
AMC99_01398	COG0189	ligase activity
AMC99_01405	COG1566	PFAM secretion protein HlyD family protein
AMC99_01406	COG2814	Major facilitator Superfamily
AMC99_01408	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AMC99_01410	COG0335	large ribosomal subunit rRNA binding
AMC99_01411	COG0336	Belongs to the RNA methyltransferase TrmD family
AMC99_01412	COG0492	ferredoxin-NADP+ reductase activity
AMC99_01414	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AMC99_01415	COG0228	four-way junction DNA binding
AMC99_01416	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AMC99_01419	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AMC99_01421	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AMC99_01422	COG3647	Membrane
AMC99_01424	COG0539	negative regulation of cytoplasmic translation
AMC99_01425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMC99_01427	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMC99_01428	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMC99_01429	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMC99_01430	COG0356	it plays a direct role in the translocation of protons across the membrane
AMC99_01436	COG2003	Belongs to the UPF0758 family
AMC99_01437	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMC99_01439	COG0284	orotidine-5'-phosphate decarboxylase activity
AMC99_01440	COG0135	phosphoribosylanthranilate isomerase activity
AMC99_01441	COG0133	tryptophan synthase activity
AMC99_01443	COG0159	tryptophan synthase activity
AMC99_01444	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AMC99_01445	COG0285	dihydrofolate synthase activity
AMC99_01446	COG2223	nitrite transmembrane transporter activity
AMC99_01447	COG4638	Rieske (2fe-2S)
AMC99_01448	COG1187	pseudouridine synthase activity
AMC99_01449	COG0742	ribosomal rna small subunit methyltransferase
AMC99_01455	COG0277	FAD linked oxidase domain protein
AMC99_01460	COG0538	isocitrate dehydrogenase activity
AMC99_01461	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMC99_01461	COG3153	acetyltransferase
AMC99_01462	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMC99_01465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMC99_01466	COG4106	trans-aconitate 2-methyltransferase activity
AMC99_01467	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AMC99_01470	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMC99_01471	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMC99_01472	COG0741	lytic transglycosylase activity
AMC99_01476	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMC99_01478	COG2258	MOSC domain
AMC99_01480	COG0384	phenazine biosynthesis protein PhzF
AMC99_01482	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AMC99_01483	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMC99_01486	COG0137	argininosuccinate synthase activity
AMC99_01487	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMC99_01492	COG0222	ribosome binding
AMC99_01494	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMC99_01498	COG0339	signal peptide processing
AMC99_01499	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AMC99_01504	COG5001	Diguanylate cyclase
AMC99_01504	COG3300	MHYT domain
AMC99_01505	COG0039	L-malate dehydrogenase activity
AMC99_01506	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AMC99_01508	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMC99_01509	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMC99_01514	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMC99_01515	COG0154	amidase activity
AMC99_01516	COG2860	membrane
AMC99_01519	COG0203	ribosomal protein L17
AMC99_01520	COG0202	RNA polymerase activity
AMC99_01521	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AMC99_01522	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AMC99_01524	COG0563	adenylate kinase activity
AMC99_01525	COG0201	protein transport
AMC99_01526	COG0200	Binds to the 23S rRNA
AMC99_01528	COG1841	ribosomal large subunit assembly
AMC99_01529	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AMC99_01530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AMC99_01531	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AMC99_01532	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AMC99_01533	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AMC99_01534	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AMC99_01535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AMC99_01536	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AMC99_01537	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AMC99_01538	COG0255	Belongs to the universal ribosomal protein uL29 family
AMC99_01539	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AMC99_01540	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AMC99_01541	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AMC99_01542	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AMC99_01543	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AMC99_01544	COG0089	rRNA binding
AMC99_01545	COG0088	Forms part of the polypeptide exit tunnel
AMC99_01546	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AMC99_01547	COG0051	transcription antitermination factor activity, RNA binding
AMC99_01548	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMC99_01549	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMC99_01550	COG0049	tRNA binding
AMC99_01551	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AMC99_01558	COG1538	Outer membrane efflux protein
AMC99_01563	COG4964	Belongs to the GSP D family
AMC99_01575	COG0583	DNA-binding transcription factor activity
AMC99_01576	COG2967	ApaG domain
AMC99_01584	COG0473	3-isopropylmalate dehydrogenase activity
AMC99_01585	COG1381	Involved in DNA repair and RecF pathway recombination
AMC99_01588	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AMC99_01590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMC99_01595	COG0625	glutathione transferase activity
AMC99_01598	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AMC99_01599	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMC99_01600	COG3706	GGDEF domain
AMC99_01600	COG0745	RESPONSE REGULATOR receiver
AMC99_01601	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AMC99_01602	COG0612	Peptidase, M16
AMC99_01603	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AMC99_01604	COG0778	Nitroreductase
AMC99_01610	COG0583	DNA-binding transcription factor activity
AMC99_01611	COG1253	flavin adenine dinucleotide binding
AMC99_01612	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AMC99_01616	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMC99_01619	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMC99_01620	COG2239	Acts as a magnesium transporter
AMC99_01622	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AMC99_01623	COG2816	NAD+ diphosphatase activity
AMC99_01630	COG1196	nuclear chromosome segregation
AMC99_01633	COG0776	regulation of translation
AMC99_01634	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMC99_01635	COG0416	fatty acid biosynthetic process
AMC99_01637	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMC99_01642	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMC99_01644	COG0215	cysteine-tRNA ligase activity
AMC99_01649	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AMC99_01652	COG1733	regulation of RNA biosynthetic process
AMC99_01654	COG3046	protein related to deoxyribodipyrimidine photolyase
AMC99_01660	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMC99_01662	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AMC99_01663	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AMC99_01664	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AMC99_01665	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AMC99_01669	COG1505	serine-type exopeptidase activity
AMC99_01672	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AMC99_01673	COG0546	phosphoglycolate phosphatase activity
AMC99_01674	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_01678	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AMC99_01681	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AMC99_01684	COG0779	Required for maturation of 30S ribosomal subunits
AMC99_01688	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AMC99_01690	COG1842	Phage shock protein A
AMC99_01698	COG2166	iron-sulfur cluster assembly
AMC99_01701	COG0824	Thioesterase
AMC99_01704	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AMC99_01706	COG0066	3-isopropylmalate dehydratase activity
AMC99_01710	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AMC99_01714	COG0248	Ppx GppA phosphatase
AMC99_01715	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AMC99_01716	COG0667	Aldo Keto reductase
AMC99_01717	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_01718	COG1960	acyl-CoA dehydrogenase activity
AMC99_01720	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMC99_01722	COG0612	Peptidase, M16
AMC99_01724	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMC99_01725	COG0047	phosphoribosylformylglycinamidine synthase activity
AMC99_01727	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMC99_01728	COG0697	spore germination
AMC99_01729	COG1215	transferase activity, transferring glycosyl groups
AMC99_01738	COG0318	PFAM AMP-dependent synthetase and ligase
AMC99_01740	COG0385	Bile acid
AMC99_01741	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMC99_01742	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AMC99_01743	COG1794	racemase activity, acting on amino acids and derivatives
AMC99_01746	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AMC99_01747	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AMC99_01749	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AMC99_01751	COG2204	response regulator
AMC99_01752	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_01754	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AMC99_01757	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AMC99_01758	COG2133	pyrroloquinoline quinone binding
AMC99_01761	COG0494	nUDIX hydrolase
AMC99_01762	COG0617	tRNA 3'-terminal CCA addition
AMC99_01766	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AMC99_01767	COG0693	protein deglycase activity
AMC99_01769	COG1104	cysteine desulfurase activity
AMC99_01770	COG1104	cysteine desulfurase activity
AMC99_01771	COG2945	thiolester hydrolase activity
AMC99_01776	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AMC99_01777	COG0745	RESPONSE REGULATOR receiver
AMC99_01778	COG2205	protein histidine kinase activity
AMC99_01779	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AMC99_01780	COG1660	Displays ATPase and GTPase activities
AMC99_01781	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMC99_01781	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMC99_01783	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMC99_01785	COG1322	Protein conserved in bacteria
AMC99_01787	COG0242	peptide deformylase activity
AMC99_01788	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AMC99_01789	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMC99_01791	COG0101	tRNA pseudouridine synthase activity
AMC99_01793	COG0252	asparaginase activity
AMC99_01797	COG0165	Argininosuccinate lyase
AMC99_01799	COG0019	diaminopimelate decarboxylase activity
AMC99_01800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMC99_01800	COG1648	precorrin-2 dehydrogenase activity
AMC99_01803	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AMC99_01809	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AMC99_01810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMC99_01812	COG0438	transferase activity, transferring glycosyl groups
AMC99_01815	COG1695	Transcriptional regulator
AMC99_01817	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AMC99_01835	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMC99_01838	COG2897	thiosulfate sulfurtransferase activity
AMC99_01839	COG0626	cystathionine gamma-synthase activity
AMC99_01841	COG1648	precorrin-2 dehydrogenase activity
AMC99_01841	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMC99_01845	COG0175	sulfate reduction
AMC99_01847	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMC99_01848	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AMC99_01849	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AMC99_01854	COG0670	Belongs to the BI1 family
AMC99_01855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AMC99_01858	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AMC99_01860	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AMC99_01861	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMC99_01863	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AMC99_01864	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMC99_01865	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AMC99_01867	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMC99_01868	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMC99_01869	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AMC99_01870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AMC99_01873	COG0275	rRNA processing
AMC99_01874	COG2001	Belongs to the MraZ family
AMC99_01877	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMC99_01882	COG2154	pterin-4-alpha-carbinolamine dehydratase
AMC99_01883	COG0531	amino acid
AMC99_01884	COG4133	protoheme IX ABC transporter activity
AMC99_01885	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMC99_01886	COG0024	Methionine aminopeptidase
AMC99_01888	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMC99_01890	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AMC99_01892	COG0347	Belongs to the P(II) protein family
AMC99_01893	COG0174	glutamine synthetase
AMC99_01902	COG0729	surface antigen
AMC99_01903	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AMC99_01904	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMC99_01905	COG2084	Dehydrogenase
AMC99_01906	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AMC99_01908	COG0805	protein transport
AMC99_01909	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMC99_01910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMC99_01911	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AMC99_01912	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AMC99_01913	COG1472	Belongs to the glycosyl hydrolase 3 family
AMC99_01915	COG0018	arginyl-trna synthetase
AMC99_01917	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AMC99_01918	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AMC99_01919	COG0328	RNA-DNA hybrid ribonuclease activity
AMC99_01920	COG3422	double-strand break repair
AMC99_01925	COG4964	Belongs to the GSP D family
AMC99_01931	COG1024	Enoyl-CoA hydratase
AMC99_01936	COG0183	Belongs to the thiolase family
AMC99_01939	COG0457	Tetratricopeptide repeat
AMC99_01941	COG1960	acyl-CoA dehydrogenase activity
AMC99_01956	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMC99_01959	COG0154	amidase activity
AMC99_01960	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMC99_01962	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AMC99_01963	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AMC99_01964	COG0564	pseudouridine synthase activity
AMC99_01966	COG0546	phosphoglycolate phosphatase activity
AMC99_01971	COG1127	ABC transporter
AMC99_01972	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMC99_01973	COG0525	valine-tRNA ligase activity
AMC99_01977	COG0730	response to heat
AMC99_01979	COG1215	transferase activity, transferring glycosyl groups
AMC99_01980	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMC99_01986	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AMC99_01991	COG0564	pseudouridine synthase activity
AMC99_01992	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMC99_01993	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMC99_02000	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AMC99_02002	COG0740	serine-type endopeptidase activity
AMC99_02004	COG0154	amidase activity
AMC99_02005	COG0544	peptidyl-prolyl cis-trans isomerase activity
AMC99_02008	COG1160	GTP binding
AMC99_02010	COG2311	Membrane
AMC99_02016	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMC99_02017	COG0540	Belongs to the ATCase OTCase family
AMC99_02018	COG0616	signal peptide processing
AMC99_02020	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMC99_02022	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AMC99_02026	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMC99_02027	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AMC99_02030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMC99_02031	COG0432	Pfam Uncharacterised protein family UPF0047
AMC99_02034	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AMC99_02035	COG0129	dihydroxy-acid dehydratase activity
AMC99_02036	COG0837	glucose binding
AMC99_02037	COG0800	Aldolase
AMC99_02040	COG0037	tRNA processing
AMC99_02047	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMC99_02051	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AMC99_02053	COG4325	translation initiation factor activity
AMC99_02056	COG1902	pentaerythritol trinitrate reductase activity
AMC99_02058	COG0321	lipoyl(octanoyl) transferase activity
AMC99_02063	COG4774	siderophore transport
AMC99_02064	COG2080	2 iron, 2 sulfur cluster binding
AMC99_02065	COG0235	Class ii aldolase
AMC99_02067	COG2198	Histidine kinase
AMC99_02067	COG0643	Histidine kinase
AMC99_02069	COG0745	RESPONSE REGULATOR receiver
AMC99_02070	COG2201	protein-glutamate methylesterase activity
AMC99_02071	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMC99_02072	COG5001	Diguanylate cyclase
AMC99_02076	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMC99_02079	COG2072	flavoprotein involved in K transport
AMC99_02080	COG0604	alcohol dehydrogenase
AMC99_02083	COG4774	siderophore transport
AMC99_02086	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AMC99_02089	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_02093	COG0745	RESPONSE REGULATOR receiver
AMC99_02094	COG1063	alcohol dehydrogenase
AMC99_02095	COG1960	acyl-CoA dehydrogenase activity
AMC99_02096	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_02104	COG0745	RESPONSE REGULATOR receiver
AMC99_02105	COG5002	protein histidine kinase activity
AMC99_02110	COG5001	Diguanylate cyclase
AMC99_02124	COG5265	(ABC) transporter
AMC99_02125	COG0612	Peptidase, M16
AMC99_02126	COG0659	secondary active sulfate transmembrane transporter activity
AMC99_02128	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AMC99_02129	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AMC99_02133	COG0629	single-stranded DNA binding
AMC99_02138	COG1999	signal sequence binding
AMC99_02139	COG2983	Belongs to the UPF0260 family
AMC99_02143	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMC99_02143	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMC99_02147	COG2885	chlorophyll binding
AMC99_02149	COG1448	Aminotransferase
AMC99_02152	COG0582	viral genome integration into host DNA
AMC99_02153	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMC99_02157	COG1538	Outer membrane efflux protein
AMC99_02161	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AMC99_02161	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AMC99_02162	COG1002	Type II restriction enzyme, methylase subunits
AMC99_02164	COG3550	peptidyl-serine autophosphorylation
AMC99_02165	COG1396	sequence-specific DNA binding
AMC99_02168	COG1937	Protein conserved in bacteria
AMC99_02169	COG2132	Multicopper oxidase
AMC99_02171	COG1482	cell wall glycoprotein biosynthetic process
AMC99_02175	COG0183	Belongs to the thiolase family
AMC99_02176	COG1024	Enoyl-CoA hydratase
AMC99_02178	COG4774	siderophore transport
AMC99_02178	COG1629	transport
AMC99_02179	COG2072	flavoprotein involved in K transport
AMC99_02181	COG1058	Belongs to the CinA family
AMC99_02181	COG1546	Belongs to the CinA family
AMC99_02184	COG0081	regulation of translation
AMC99_02185	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AMC99_02193	COG1696	Membrane protein involved in D-alanine export
AMC99_02196	COG1115	amino acid carrier protein
AMC99_02204	COG0318	PFAM AMP-dependent synthetase and ligase
AMC99_02210	COG4251	negative regulation of phosphorylation
AMC99_02213	COG0784	Response regulator, receiver
AMC99_02213	COG2205	protein histidine kinase activity
AMC99_02216	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AMC99_02218	COG0531	amino acid
AMC99_02219	COG4638	Rieske (2fe-2S)
AMC99_02221	COG4566	intracellular signal transduction
AMC99_02225	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AMC99_02227	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMC99_02227	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AMC99_02229	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMC99_02235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AMC99_02237	COG0489	protein tyrosine kinase activity
AMC99_02239	COG0330	HflC and HflK could
AMC99_02240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMC99_02241	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMC99_02242	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMC99_02247	COG2813	Specifically methylates the guanine in position
AMC99_02247	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMC99_02248	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMC99_02249	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMC99_02250	COG0287	Prephenate dehydrogenase
AMC99_02254	COG2884	Cell division ATP-binding protein ftsE
AMC99_02260	COG1522	sequence-specific DNA binding
AMC99_02262	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AMC99_02266	COG0717	Belongs to the dCTP deaminase family
AMC99_02268	COG3268	Saccharopine dehydrogenase
AMC99_02269	COG4206	TonB-dependent receptor
AMC99_02273	COG2095	MarC family integral membrane protein
AMC99_02275	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AMC99_02276	COG0762	integral membrane protein
AMC99_02277	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMC99_02282	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMC99_02282	COG1372	Participates in initiation and elongation during chromosome replication
AMC99_02287	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMC99_02287	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMC99_02294	COG1131	(ABC) transporter
AMC99_02300	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AMC99_02303	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMC99_02303	COG0519	Catalyzes the synthesis of GMP from XMP
AMC99_02306	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMC99_02309	COG0187	DNA topoisomerase II activity
AMC99_02314	COG0204	Acyl-transferase
AMC99_02316	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMC99_02318	COG1960	acyl-CoA dehydrogenase activity
AMC99_02319	COG3920	Histidine kinase
AMC99_02321	COG1125	glycine betaine transport
AMC99_02321	COG0517	IMP dehydrogenase activity
AMC99_02324	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AMC99_02325	COG0318	PFAM AMP-dependent synthetase and ligase
AMC99_02326	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AMC99_02327	COG3284	Transcriptional regulator
AMC99_02327	COG3284	Transcriptional regulator
AMC99_02328	COG1012	belongs to the aldehyde dehydrogenase family
AMC99_02331	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AMC99_02332	COG0352	thiamine-phosphate diphosphorylase activity
AMC99_02333	COG1674	ftsk spoiiie
AMC99_02334	COG3706	GGDEF domain
AMC99_02340	COG0745	RESPONSE REGULATOR receiver
AMC99_02341	COG2205	protein histidine kinase activity
AMC99_02342	COG0433	COG0433 Predicted ATPase
AMC99_02344	COG0564	pseudouridine synthase activity
AMC99_02346	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AMC99_02348	COG1785	Belongs to the alkaline phosphatase family
AMC99_02359	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMC99_02360	COG0183	Belongs to the thiolase family
AMC99_02361	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AMC99_02363	COG3186	Phenylalanine-4-hydroxylase
AMC99_02366	COG1968	undecaprenyl-diphosphatase activity
AMC99_02367	COG3590	peptidase
AMC99_02368	COG1132	(ABC) transporter
AMC99_02370	COG0531	amino acid
AMC99_02372	COG0183	Belongs to the thiolase family
AMC99_02378	COG0070	glutamate synthase
AMC99_02378	COG0069	glutamate synthase activity
AMC99_02378	COG0067	glutamate synthase
AMC99_02382	COG1024	Enoyl-CoA hydratase
AMC99_02383	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AMC99_02390	COG0495	leucyl-tRNA aminoacylation
AMC99_02393	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_02396	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AMC99_02400	COG0739	heme binding
AMC99_02401	COG2833	Protein of unknown function (DUF455)
AMC99_02402	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AMC99_02403	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AMC99_02405	COG2957	Belongs to the agmatine deiminase family
AMC99_02408	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AMC99_02412	COG1476	TRANSCRIPTIONal
AMC99_02413	COG0596	Alpha beta hydrolase
AMC99_02417	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMC99_02422	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AMC99_02423	COG4152	abc transporter atp-binding protein
AMC99_02429	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
AMC99_02432	COG0776	regulation of translation
AMC99_02433	COG2188	Transcriptional regulator
AMC99_02434	COG3104	oligopeptide transport
AMC99_02435	COG0804	urea catabolic process
AMC99_02436	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AMC99_02440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMC99_02442	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMC99_02444	COG0138	bifunctional purine biosynthesis protein purh
AMC99_02467	COG2272	Belongs to the type-B carboxylesterase lipase family
AMC99_02472	COG3275	phosphorelay sensor kinase activity
AMC99_02473	COG3279	Response regulator of the LytR AlgR family
AMC99_02477	COG0590	tRNA wobble adenosine to inosine editing
AMC99_02478	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AMC99_02482	COG0151	Belongs to the GarS family
AMC99_02483	COG1570	exodeoxyribonuclease VII activity
AMC99_02485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMC99_02489	COG0316	Belongs to the HesB IscA family
AMC99_02492	COG2151	metal-sulfur cluster biosynthetic enzyme
AMC99_02493	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMC99_02494	COG0719	Fe-S assembly protein
AMC99_02495	COG0396	ATPase activity
AMC99_02498	COG0719	Fe-S assembly protein
AMC99_02499	COG1959	2 iron, 2 sulfur cluster binding
AMC99_02504	COG0167	dihydroorotate dehydrogenase activity
AMC99_02505	COG0405	Gamma-glutamyltransferase
AMC99_02506	COG1022	Amp-dependent synthetase and ligase
AMC99_02508	COG2022	thiamine diphosphate biosynthetic process
AMC99_02510	COG1612	heme a metabolic process
AMC99_02513	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AMC99_02514	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AMC99_02522	COG3275	phosphorelay sensor kinase activity
AMC99_02524	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMC99_02530	COG0316	Belongs to the HesB IscA family
AMC99_02535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMC99_02536	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AMC99_02537	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMC99_02538	COG0237	dephospho-CoA kinase activity
AMC99_02539	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AMC99_02540	COG0424	maF-like protein
AMC99_02541	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AMC99_02542	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AMC99_02544	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AMC99_02547	COG0069	glutamate synthase activity
AMC99_02550	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AMC99_02551	COG0445	tRNA wobble uridine modification
AMC99_02552	COG0357	Ribosomal RNA small subunit methyltransferase G
AMC99_02553	COG1192	Involved in chromosome partitioning
AMC99_02554	COG1475	DNA binding
AMC99_02559	COG1956	GAF domain-containing protein
AMC99_02562	COG1960	acyl-CoA dehydrogenase activity
AMC99_02563	COG0009	L-threonylcarbamoyladenylate synthase
AMC99_02565	COG1329	Transcriptional regulator
AMC99_02569	COG0741	lytic transglycosylase activity
AMC99_02569	COG0739	heme binding
AMC99_02569	COG1196	nuclear chromosome segregation
AMC99_02570	COG0113	porphobilinogen synthase activity
AMC99_02574	COG1872	DUF167
AMC99_02576	COG1793	dna ligase
AMC99_02584	COG0318	PFAM AMP-dependent synthetase and ligase
AMC99_02586	COG0739	heme binding
AMC99_02587	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMC99_02588	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AMC99_02589	COG0799	negative regulation of ribosome biogenesis
AMC99_02590	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AMC99_02592	COG0793	Belongs to the peptidase S41A family
AMC99_02594	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AMC99_02596	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMC99_02597	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMC99_02600	COG1091	dTDP-4-dehydrorhamnose reductase activity
AMC99_02601	COG1088	dTDP-glucose 4,6-dehydratase activity
AMC99_02602	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AMC99_02608	COG0297	glycogen (starch) synthase activity
AMC99_02613	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AMC99_02619	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMC99_02620	COG1295	ribonuclease BN
AMC99_02621	COG0484	heat shock protein binding
AMC99_02622	COG0259	pyridoxamine-phosphate oxidase activity
AMC99_02624	COG0384	phenazine biosynthesis protein PhzF
AMC99_02628	COG0482	sulfurtransferase activity
AMC99_02632	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMC99_02634	COG2733	membrane
AMC99_02637	COG2086	electron transfer activity
AMC99_02639	COG0045	succinate-CoA ligase (ADP-forming) activity
AMC99_02641	COG1218	3'(2'),5'-bisphosphate nucleotidase
AMC99_02643	COG1253	flavin adenine dinucleotide binding
AMC99_02645	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AMC99_02646	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMC99_02647	COG0196	riboflavin kinase activity
AMC99_02650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AMC99_02652	COG0588	phosphoglycerate mutase activity
AMC99_02657	COG3428	Bacterial PH domain
AMC99_02662	COG0308	aminopeptidase N
AMC99_02665	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AMC99_02667	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMC99_02672	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AMC99_02673	COG1192	Involved in chromosome partitioning
AMC99_02677	COG1201	RNA secondary structure unwinding
AMC99_02688	COG1494	fructose-1,6-bisphosphatase
AMC99_02692	COG1028	Short-chain dehydrogenase reductase Sdr
AMC99_02693	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AMC99_02694	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AMC99_02698	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AMC99_02699	COG0072	phenylalanine-tRNA ligase activity
AMC99_02700	COG4771	TonB-dependent receptor
AMC99_02703	COG2267	carboxylic ester hydrolase activity
AMC99_02706	COG0347	Belongs to the P(II) protein family
AMC99_02707	COG0004	ammonium transporteR
AMC99_02708	COG4771	TonB-dependent receptor
AMC99_02714	COG1473	amidohydrolase
AMC99_02716	COG1278	Cold shock
AMC99_02717	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMC99_02718	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMC99_02721	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AMC99_02723	COG2032	superoxide dismutase activity
AMC99_02724	COG2885	chlorophyll binding
AMC99_02724	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AMC99_02730	COG1238	metal cluster binding
AMC99_02731	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMC99_02733	COG1764	response to oxidative stress
AMC99_02734	COG0156	8-amino-7-oxononanoate synthase activity
AMC99_02735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMC99_02744	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AMC99_02746	COG0747	negative chemotaxis
AMC99_02748	COG3483	tryptophan 2,3-dioxygenase activity
AMC99_02749	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AMC99_02752	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMC99_02755	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMC99_02759	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AMC99_02760	COG0280	phosphate acetyltransferase
AMC99_02760	COG0281	malic enzyme
AMC99_02765	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMC99_02766	COG0745	RESPONSE REGULATOR receiver
AMC99_02768	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AMC99_02769	COG1137	ATPase activity
AMC99_02771	COG0668	transmembrane transport
AMC99_02772	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AMC99_02774	COG0124	histidyl-tRNA synthetase
AMC99_02775	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AMC99_02776	COG2890	protein-(glutamine-N5) methyltransferase activity
AMC99_02778	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AMC99_02779	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AMC99_02780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMC99_02785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMC99_02787	COG3920	Histidine kinase
AMC99_02788	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMC99_02788	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMC99_02793	COG0459	protein refolding
AMC99_02794	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMC99_02795	COG0534	Mate efflux family protein
AMC99_02797	COG0222	ribosome binding
AMC99_02798	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AMC99_02802	COG3655	Transcriptional regulator
AMC99_02806	COG0085	RNA polymerase activity
AMC99_02807	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AMC99_02811	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AMC99_02811	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMC99_02814	COG0469	pyruvate kinase activity
AMC99_02816	COG3750	Belongs to the UPF0335 family
AMC99_02817	COG0393	Putative heavy-metal-binding