locus-tag	class	description
A6F65_00001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
A6F65_00002	ENOG4105D06	uba thif-type nad fad binding protein
A6F65_00005	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A6F65_00012	ENOG4107QJT	sodium dicarboxylate symporter
A6F65_00013	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A6F65_00014	ENOG4108TGY	Glutathione S-transferase
A6F65_00017	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A6F65_00019	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
A6F65_00020	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
A6F65_00021	ENOG4105VG0	50S ribosomal protein l34
A6F65_00024	ENOG4105C0P	Mg chelatase subunit ChlI
A6F65_00026	ENOG4105CUB	amino acid
A6F65_00029	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
A6F65_00034	ENOG4105CHR	reductase
A6F65_00036	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A6F65_00040	ENOG41073TP	transcriptional regulator
A6F65_00042	ENOG410846T	CoA-transferase family III
A6F65_00043	ENOG4105C1G	acyl-Coa dehydrogenase
A6F65_00045	ENOG4105CI0	Citrate lyase
A6F65_00048	ENOG4105D05	Receptor
A6F65_00050	ENOG4107ZSV	Receptor
A6F65_00053	ENOG4105CQB	FAD linked oxidase domain protein
A6F65_00056	ENOG4105C26	Dehydrogenase
A6F65_00059	ENOG4108UAU	isochorismatase
A6F65_00062	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A6F65_00063	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A6F65_00064	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
A6F65_00067	ENOG4108XM1	transcriptional regulator AsnC family
A6F65_00069	ENOG4105DJB	Major Facilitator Superfamily
A6F65_00071	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
A6F65_00076	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A6F65_00078	ENOG4107YPT	transcriptional regulator
A6F65_00081	ENOG4105YK5	50S ribosomal protein L36
A6F65_00086	ENOG4105KG3	cytidine deaminase
A6F65_00088	ENOG4108ZTZ	UPF0262 protein
A6F65_00090	ENOG4105DZQ	phospholipase D Transphosphatidylase
A6F65_00091	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
A6F65_00095	ENOG4105DG6	mannose-6-phosphate isomerase
A6F65_00097	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
A6F65_00099	ENOG4108IEG	Formate dehydrogenase Alpha subunit
A6F65_00100	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A6F65_00101	ENOG4107QIZ	NADH dehydrogenase
A6F65_00103	ENOG4105EQ2	LysR family Transcriptional regulator
A6F65_00105	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A6F65_00107	ENOG4105DDR	sarcosine oxidase (Beta subunit)
A6F65_00110	ENOG4108IGT	Dipeptidase
A6F65_00111	ENOG4105C26	Dehydrogenase
A6F65_00112	ENOG4108M0I	Transcriptional regulator
A6F65_00113	ENOG4105DG4	malate L-lactate dehydrogenase
A6F65_00114	ENOG4107RDJ	Sulfotransferase
A6F65_00115	ENOG4107ZSV	Receptor
A6F65_00116	ENOG4105C94	Transporter
A6F65_00117	ENOG4105CKU	formyltetrahydrofolate synthetase
A6F65_00118	ENOG4106NZI	LysR family Transcriptional regulator
A6F65_00120	ENOG4105DVW	rieske (2Fe-2S)
A6F65_00122	ENOG4105H1N	peptidase, M24
A6F65_00124	ENOG4105F5V	trimethylamine methyltransferase
A6F65_00127	ENOG4107VP5	methyltetrahydrofolate corrinoid iron-sulfur protein methyltransferase
A6F65_00131	ENOG4108Q52	Methyltransferase cognate corrinoid protein
A6F65_00132	ENOG4105ECQ	AraC Family Transcriptional Regulator
A6F65_00135	ENOG4108QDA	dioxygenase
A6F65_00137	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A6F65_00141	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A6F65_00149	ENOG4106CY5	excisionase
A6F65_00151	ENOG4105DFP	Integrase
A6F65_00155	ENOG4107QX8	SPFH domain, Band 7 family protein
A6F65_00157	ENOG4105K63	Thioredoxin
A6F65_00158	ENOG4105K63	Thioredoxin
A6F65_00166	ENOG4105CFH	Aspartokinase
A6F65_00167	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A6F65_00168	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
A6F65_00169	ENOG4105KUZ	arsenate reductase
A6F65_00172	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
A6F65_00174	ENOG4105CDY	transcriptional regulatory protein
A6F65_00176	ENOG4105K8R	UPF0145 protein
A6F65_00177	ENOG4105Y2X	UPF0335 protein
A6F65_00179	ENOG4105CA9	Pyruvate kinase
A6F65_00180	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
A6F65_00184	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6F65_00185	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6F65_00188	ENOG4105VMP	Transcriptional regulator
A6F65_00191	ENOG4108VZM	50s ribosomal protein L10
A6F65_00192	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A6F65_00195	ENOG4108YIQ	Alpha beta hydrolase
A6F65_00196	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A6F65_00197	ENOG4107QI1	Mate efflux family protein
A6F65_00198	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A6F65_00199	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A6F65_00203	ENOG4105C2M	dna polymerase I
A6F65_00204	ENOG410903D	sensor protein
A6F65_00206	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A6F65_00210	ENOG4105DNH	Major Facilitator
A6F65_00216	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A6F65_00217	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A6F65_00219	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A6F65_00220	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A6F65_00221	ENOG4105CUT	histidyl-tRNA synthetase
A6F65_00222	ENOG4105F0N	pyrophosphate phospho-hydrolase
A6F65_00225	ENOG4105D8X	mechanosensitive ion channel
A6F65_00227	ENOG4108IUZ	ABC transporter
A6F65_00228	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6F65_00229	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
A6F65_00230	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A6F65_00231	ENOG4105S2T	inner membrane protein YbcI
A6F65_00232	ENOG4108R99	pseudouridine synthase
A6F65_00234	ENOG4105C6K	Malic enzyme
A6F65_00235	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A6F65_00240	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
A6F65_00244	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
A6F65_00246	ENOG4105DEF	Extracellular solute-binding protein, family 5
A6F65_00248	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A6F65_00255	ENOG4108UXN	response regulator
A6F65_00257	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A6F65_00258	ENOG4108Z9K	Osmotically inducible protein
A6F65_00262	ENOG41082IR	Excinuclease ABC C subunit domain protein
A6F65_00263	ENOG4105EFC	phage portal protein HK97 family
A6F65_00279	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A6F65_00280	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A6F65_00281	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
A6F65_00282	ENOG4105DBV	ornithine carbamoyltransferase
A6F65_00283	ENOG4105C8Y	Acetylornithine aminotransferase
A6F65_00285	ENOG4105EE5	Membrane protein terC
A6F65_00289	ENOG4105BZU	Histidine kinase
A6F65_00290	ENOG4108YZA	Nitrogen regulatory protein pii
A6F65_00293	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
A6F65_00295	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A6F65_00296	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A6F65_00297	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A6F65_00298	ENOG41082BR	50S ribosomal protein L35
A6F65_00302	ENOG4105CBT	Fructose-1,6-bisphosphatase
A6F65_00303	ENOG4105D6E	homoserine dehydrogenase
A6F65_00310	ENOG4107QRT	dEAD DEAH box helicase
A6F65_00315	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
A6F65_00316	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A6F65_00317	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A6F65_00318	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A6F65_00319	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A6F65_00320	ENOG4107QP3	malate synthase g
A6F65_00322	ENOG4107RET	Isocitrate lyase
A6F65_00323	ENOG4105CFF	transcriptional regulator
A6F65_00325	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
A6F65_00327	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A6F65_00328	ENOG4105EIX	cytochrome c1
A6F65_00329	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A6F65_00330	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A6F65_00331	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A6F65_00332	ENOG4105CD8	aminopeptidase N
A6F65_00337	ENOG4105CKV	Membrane
A6F65_00341	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A6F65_00343	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
A6F65_00345	ENOG4108IGT	Dipeptidase
A6F65_00346	ENOG4105DTN	riboflavin biosynthesis protein ribF
A6F65_00348	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A6F65_00351	ENOG4108ZG0	Ompa motb domain protein
A6F65_00352	ENOG4107TK4	histidinol-phosphate phosphatase
A6F65_00353	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A6F65_00356	ENOG4105BZJ	Electron transfer flavoprotein
A6F65_00357	ENOG4105C10	Electron transfer flavoprotein
A6F65_00360	ENOG4106BRA	Membrane
A6F65_00362	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
A6F65_00366	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A6F65_00370	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A6F65_00371	ENOG41076HS	cation diffusion facilitator family transporter
A6F65_00372	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
A6F65_00373	ENOG4105DVC	DnaJ domain protein
A6F65_00374	ENOG4107U9T	Pfam:Ribonuclease_BN
A6F65_00375	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A6F65_00381	ENOG4105CN1	protease
A6F65_00382	ENOG41063SB	peptidase
A6F65_00383	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
A6F65_00385	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
A6F65_00386	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
A6F65_00387	ENOG4105DR5	peptidase
A6F65_00394	ENOG4107T0X	DNA ligase
A6F65_00396	ENOG4107T0X	DNA ligase
A6F65_00398	ENOG4108Z0R	Transferase
A6F65_00401	ENOG4105D52	delta-aminolevulinic acid dehydratase
A6F65_00402	ENOG4105DR5	peptidase
A6F65_00404	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A6F65_00405	ENOG4108Z4U	Ferredoxin
A6F65_00407	ENOG4108VJ1	Transcriptional regulator (CarD family
A6F65_00418	ENOG4105FA0	parb-like partition protein
A6F65_00419	ENOG4107QJE	Chromosome Partitioning Protein
A6F65_00420	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
A6F65_00421	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
A6F65_00422	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
A6F65_00425	ENOG4105CBC	glutamate synthase
A6F65_00428	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A6F65_00429	ENOG4108YXA	Membrane
A6F65_00430	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
A6F65_00431	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
A6F65_00432	ENOG4108UHJ	MAF-like protein
A6F65_00433	ENOG4105E2X	shikimate dehydrogenase
A6F65_00434	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A6F65_00435	ENOG4107RZZ	dna polymerase iii epsilon subunit
A6F65_00436	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
A6F65_00437	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
A6F65_00442	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
A6F65_00443	ENOG41080XP	Cbs domain
A6F65_00446	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A6F65_00449	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A6F65_00450	ENOG4107GFK	fumarate
A6F65_00451	ENOG4105C2F	Histidine kinase
A6F65_00452	ENOG4108NEV	two component transcriptional regulator, LytTR family
A6F65_00456	ENOG4108UJD	30S ribosomal protein S9
A6F65_00457	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A6F65_00460	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
A6F65_00462	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
A6F65_00465	ENOG4108IQE	Amp-dependent synthetase and ligase
A6F65_00466	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A6F65_00467	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
A6F65_00468	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
A6F65_00472	ENOG4105JRK	feS assembly protein SufD
A6F65_00474	ENOG4105VG1	fes assembly suf system protein
A6F65_00476	ENOG4108Z4V	iron-sulfur cluster assembly
A6F65_00481	ENOG4105C12	Phosphoribosylglycinamide synthetase
A6F65_00482	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A6F65_00484	ENOG4105FRN	stage II sporulation protein
A6F65_00486	ENOG4107RDJ	Sulfotransferase
A6F65_00487	ENOG4107RDJ	Sulfotransferase
A6F65_00488	ENOG4105KDC	50s ribosomal protein l28
A6F65_00489	ENOG4108Z6B	deaminase
A6F65_00492	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A6F65_00493	ENOG4105DY9	regulatoR
A6F65_00494	ENOG4108HRK	Histidine kinase
A6F65_00496	ENOG4105D0M	Protease HtpX homolog
A6F65_00505	ENOG4105CYB	regulatoR
A6F65_00507	ENOG4105E0Y	RtcB Protein
A6F65_00509	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
A6F65_00517	ENOG4105FDP	GntR family transcriptional regulator
A6F65_00518	ENOG4105DUX	Transporter
A6F65_00519	ENOG4105CQM	Urea amidohydrolase subunit alpha
A6F65_00525	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A6F65_00527	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A6F65_00530	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A6F65_00532	ENOG4105DJV	ribulose-phosphate 3-epimerase
A6F65_00541	ENOG4105BZ8	glutamate synthase
A6F65_00544	ENOG4105E0X	reductase
A6F65_00546	ENOG4108IUX	(ABC) transporter
A6F65_00547	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
A6F65_00549	ENOG4105C7I	Dehydrogenase
A6F65_00555	ENOG4105C8T	Leucyl-tRNA synthetase
A6F65_00563	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A6F65_00565	ENOG4105DR5	peptidase
A6F65_00566	ENOG4105ED9	Protein of unknown function (DUF455)
A6F65_00567	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A6F65_00568	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
A6F65_00570	ENOG4105DWY	Agmatine deiminase
A6F65_00574	ENOG4105C22	threonyL-tRNA synthetase
A6F65_00587	ENOG4105CG5	Glycosyl transferase (Group 1
A6F65_00591	ENOG4105K64	Glycosyl transferase, family 2
A6F65_00592	ENOG4106CD9	glycosyl transferase group 1
A6F65_00598	ENOG4107U9H	DNA polymerase
A6F65_00599	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
A6F65_00603	ENOG4105CPK	Glycosyl transferase (Group 1
A6F65_00608	ENOG4105BZ1	(ABC) transporter
A6F65_00609	ENOG4105C9K	Endothelin-converting enzyme 1
A6F65_00610	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A6F65_00613	ENOG4105MIR	Phenylalanine 4-monooxygenase
A6F65_00616	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A6F65_00619	ENOG4105KSC	Transcriptional regulator, TraR DksA family
A6F65_00620	ENOG4105DJ4	phosphatidylserine decarboxylase
A6F65_00622	ENOG4107QJN	gtp cyclohydrolase ii
A6F65_00625	ENOG4105W0E	50S ribosomal protein L33
A6F65_00626	ENOG4108YZN	class I peptide chain release factor
A6F65_00628	ENOG4105CHM	Aminotransferase
A6F65_00630	ENOG4105D7A	ATP-binding protein
A6F65_00633	ENOG4105JJR	Histidine kinase
A6F65_00634	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A6F65_00639	ENOG4105C1J	atp-dependent rna helicase
A6F65_00643	ENOG4105DFA	alanine racemase domain protein
A6F65_00646	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
A6F65_00647	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A6F65_00650	ENOG4105C1G	acyl-Coa dehydrogenase
A6F65_00651	ENOG4107QX3	carboxylase
A6F65_00657	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6F65_00658	ENOG4105EJQ	L-serine dehydratase
A6F65_00663	ENOG4105CSM	endonuclease III
A6F65_00665	ENOG4105ECQ	AraC Family Transcriptional Regulator
A6F65_00670	ENOG4105DA5	(ABC) transporter
A6F65_00672	ENOG4108IYU	L-aspartate oxidase
A6F65_00676	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A6F65_00688	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
A6F65_00694	ENOG4105CSR	polyphosphate kinase 2
A6F65_00696	ENOG4105CAS	nag kinase
A6F65_00699	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A6F65_00701	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A6F65_00705	ENOG4107ENK	receptor
A6F65_00707	ENOG4105DHP	deoxycytidine triphosphate deaminase
A6F65_00708	ENOG4105C26	Dehydrogenase
A6F65_00711	ENOG41062D9	Histidine kinase
A6F65_00714	ENOG4107QX3	carboxylase
A6F65_00717	ENOG4108UKI	Enoyl-CoA hydratase
A6F65_00724	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A6F65_00729	ENOG4105C0B	DNA polymerase III (alpha subunit)
A6F65_00730	ENOG4105BZU	Histidine kinase
A6F65_00731	ENOG4105BZU	Histidine kinase
A6F65_00735	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
A6F65_00739	ENOG4105ETE	Transcriptional regulator (LacI family
A6F65_00742	ENOG4105EDQ	levansucrase EC 2.4.1.10
A6F65_00746	ENOG4106D71	domain protein
A6F65_00747	ENOG4105CAK	Cell division ATP-binding protein ftsE
A6F65_00750	ENOG4105E9Q	Acyl-transferase
A6F65_00752	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A6F65_00754	ENOG4105DWV	Homoserine O-trans-acetylase
A6F65_00755	ENOG4105C4W	S-formylglutathione hydrolase
A6F65_00758	ENOG4107QPD	alcohol dehydrogenase
A6F65_00762	ENOG4105CT3	Monooxygenase
A6F65_00763	ENOG4105CEV	competence damage-inducible protein
A6F65_00765	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A6F65_00766	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A6F65_00769	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A6F65_00770	ENOG4105PM1	preprotein translocase subunit SecE
A6F65_00771	ENOG4105BZG	amino acid carrier protein
A6F65_00776	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
A6F65_00781	ENOG4107RCI	amp-dependent synthetase and ligase
A6F65_00790	ENOG4105BZU	Histidine kinase
A6F65_00793	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6F65_00794	ENOG4105BZU	Histidine kinase
A6F65_00801	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A6F65_00802	ENOG4105C4K	Nad synthetase
A6F65_00804	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A6F65_00806	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A6F65_00809	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
A6F65_00810	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
A6F65_00811	ENOG4105D1F	ATP-binding protein
A6F65_00812	ENOG4107RIZ	hflk protein
A6F65_00815	ENOG4108JQC	penicillin-binding protein 1A
A6F65_00816	ENOG4105E0X	reductase
A6F65_00818	ENOG4107QJE	Chromosome Partitioning Protein
A6F65_00828	ENOG4105EQK	-acetyltransferase
A6F65_00829	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A6F65_00835	ENOG4108IJ1	Dehydrogenase
A6F65_00837	ENOG4107R51	Glycosyl transferase, family 2
A6F65_00840	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A6F65_00841	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
A6F65_00842	ENOG4105BZ1	(ABC) transporter
A6F65_00845	ENOG4105CG3	alpha amylase, catalytic region
A6F65_00849	ENOG4105ETE	Transcriptional regulator (LacI family
A6F65_00852	ENOG4105CGF	Aromatic amino acid aminotransferase
A6F65_00855	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A6F65_00859	ENOG4108ZZ3	UPF0260 protein
A6F65_00860	ENOG4108ZX6	Electron transport protein SCO1 SenC
A6F65_00864	ENOG4105CE1	Ferrous iron transport protein b
A6F65_00865	ENOG4108UUM	single-stranded DNA-binding protein
A6F65_00866	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
A6F65_00874	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
A6F65_00876	ENOG4105CHH	sulfate transporter
A6F65_00878	ENOG4108JJ7	ABC transporter
A6F65_00892	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A6F65_00894	ENOG4105ETE	Transcriptional regulator (LacI family
A6F65_00896	ENOG4105KJF	protein tyrosine phosphatase
A6F65_00897	ENOG4105FGM	Fructosamine kinase
A6F65_00898	ENOG4108UKI	Enoyl-CoA hydratase
A6F65_00899	ENOG4105C1G	acyl-Coa dehydrogenase
A6F65_00904	ENOG4105CFC	Transporter
A6F65_00907	ENOG4106KS4	Sulfatase
A6F65_00909	ENOG41060NJ	transcriptional regulator
A6F65_00912	ENOG4105CBG	Sulfatase
A6F65_00914	ENOG4105ENH	Sulfatase
A6F65_00917	ENOG4105ENH	Sulfatase
A6F65_00918	ENOG4105E6M	Sulphatase-modifying factor protein
A6F65_00919	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
A6F65_00922	ENOG4108RMU	ferritin dps family protein
A6F65_00927	ENOG4107QM2	Aldo Keto reductase
A6F65_00930	ENOG4108URH	decarboxylase
A6F65_00932	ENOG4107RMN	lycopene cyclase
A6F65_00941	ENOG4105CJ1	ABC, transporter
A6F65_00946	ENOG4105CFC	Transporter
A6F65_00949	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
A6F65_00951	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
A6F65_00953	ENOG4105QNF	Outer membrane lipoprotein
A6F65_00955	ENOG4108UPT	UPF0178 protein
A6F65_00967	ENOG4108V1U	phospholipid-binding protein
A6F65_00976	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
A6F65_00979	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A6F65_00982	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
A6F65_00984	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
A6F65_00985	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A6F65_00987	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
A6F65_00989	ENOG4105K59	histidine triad (HIT) protein
A6F65_00992	ENOG4105M8F	Biopolymer transport protein exbD tolR
A6F65_00994	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
A6F65_00995	ENOG4105KCK	Peptidoglycan-associated lipoprotein
A6F65_00997	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A6F65_00999	ENOG4105C28	cystathionine
A6F65_01002	ENOG4105C8P	)-transporter
A6F65_01008	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
A6F65_01011	ENOG4105CZN	Potassium uptake protein
A6F65_01024	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
A6F65_01026	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
A6F65_01027	ENOG4107KJX	Transcriptional regulator
A6F65_01029	ENOG4105CHR	reductase
A6F65_01033	ENOG4105C1G	acyl-Coa dehydrogenase
A6F65_01034	ENOG4105C26	Dehydrogenase
A6F65_01037	ENOG4108ZJ4	polysaccharide deacetylase
A6F65_01038	ENOG4105E39	Enoyl-CoA hydratase
A6F65_01041	ENOG4105ETE	Transcriptional regulator (LacI family
A6F65_01042	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A6F65_01045	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
A6F65_01048	ENOG4105DCF	alanine dehydrogenase
A6F65_01049	ENOG4105VTN	Protein of unknown function (DUF1311)
A6F65_01051	ENOG41074H6	response regulator
A6F65_01052	ENOG41080PD	NADH ubiquinone oxidoreductase 41 kD complex I subunit
A6F65_01054	ENOG4105UYK	outer membrane protein a
A6F65_01056	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A6F65_01057	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A6F65_01058	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A6F65_01061	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A6F65_01067	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
A6F65_01072	ENOG4108ZXC	Two component transcriptional regulator, luxr family
A6F65_01076	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
A6F65_01077	ENOG4108UXN	response regulator
A6F65_01079	ENOG4105CV8	reductase
A6F65_01080	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A6F65_01084	ENOG4105HDK	L-asparaginase
A6F65_01087	ENOG4105K63	Thioredoxin
A6F65_01088	ENOG4105CH7	arginosuccinase
A6F65_01091	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A6F65_01095	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
A6F65_01097	ENOG4105C02	permease
A6F65_01098	ENOG4105C3F	Signal peptidase i
A6F65_01099	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
A6F65_01100	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
A6F65_01101	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A6F65_01103	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A6F65_01104	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A6F65_01106	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
A6F65_01107	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
A6F65_01109	ENOG4105D98	threonine synthase
A6F65_01113	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A6F65_01117	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
A6F65_01119	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
A6F65_01120	ENOG4105K46	50S ribosomal protein l27
A6F65_01123	ENOG4108S01	response regulator
A6F65_01124	ENOG4105BZU	Histidine kinase
A6F65_01130	ENOG4108Z03	MAF-like protein
A6F65_01131	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A6F65_01133	ENOG4105CBX	hi0933 family
A6F65_01134	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
A6F65_01140	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
A6F65_01143	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A6F65_01147	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A6F65_01149	ENOG4105D74	hydrolase
A6F65_01150	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A6F65_01151	ENOG4105EUB	pirin domain protein
A6F65_01155	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
A6F65_01158	ENOG4108JQC	penicillin-binding protein 1A
A6F65_01159	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A6F65_01160	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A6F65_01161	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A6F65_01162	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A6F65_01167	ENOG4108RWN	rrna methyltransferase
A6F65_01168	ENOG41080Z8	PHOSPHOCARRIER protein
A6F65_01169	ENOG4108EQA	pts system
A6F65_01170	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
A6F65_01171	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
A6F65_01172	ENOG4105EB3	Histidine kinase
A6F65_01173	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A6F65_01174	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
A6F65_01179	ENOG4105C3M	thioredoxin reductase
A6F65_01185	ENOG4105DHZ	alpha beta
A6F65_01186	ENOG4105C3J	Cysteine desulfurase
A6F65_01187	ENOG4105C3J	Cysteine desulfurase
A6F65_01191	ENOG4108Z0Z	intracellular protease Pfpi family
A6F65_01192	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6F65_01193	ENOG4105BZU	Histidine kinase
A6F65_01194	ENOG4105DJ0	Poly(A) Polymerase
A6F65_01199	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A6F65_01200	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A6F65_01202	ENOG4105CEC	DNA methylase N-4 N-6
A6F65_01203	ENOG4105EEI	dihydropteroate synthase
A6F65_01204	ENOG4105CHR	reductase
A6F65_01207	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A6F65_01209	ENOG4105W8H	transhydrogenase (subunit alpha
A6F65_01210	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A6F65_01218	ENOG4105DFI	Membrane
A6F65_01223	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A6F65_01225	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A6F65_01226	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A6F65_01228	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A6F65_01229	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A6F65_01234	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A6F65_01236	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A6F65_01238	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A6F65_01240	ENOG4105CEN	a g-specific adenine glycosylase
A6F65_01245	ENOG4105BZU	Histidine kinase
A6F65_01247	ENOG4105CJW	magnesium transporter
A6F65_01248	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A6F65_01252	ENOG4107RCQ	(CBS) domain
A6F65_01253	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
A6F65_01256	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A6F65_01259	ENOG41090R7	Ferric uptake
A6F65_01260	ENOG4108YXV	Transcriptional regulator
A6F65_01262	ENOG41072GX	Peptidase M22 Glycoprotease
A6F65_01263	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
A6F65_01264	ENOG41083MR	nifu domain-containing protein
A6F65_01266	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
A6F65_01271	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A6F65_01272	ENOG4105CYM	Glutathione S-transferase
A6F65_01276	ENOG4105C72	UPF0176 protein
A6F65_01278	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A6F65_01280	ENOG4105DX0	Hemolysin A
A6F65_01283	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
A6F65_01284	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A6F65_01291	ENOG4105NWN	ApaG protein
A6F65_01302	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A6F65_01304	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A6F65_01305	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A6F65_01306	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A6F65_01307	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A6F65_01308	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A6F65_01309	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A6F65_01310	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A6F65_01311	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A6F65_01312	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A6F65_01313	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A6F65_01314	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A6F65_01315	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A6F65_01316	ENOG41083MP	50s ribosomal protein l29
A6F65_01317	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A6F65_01318	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A6F65_01319	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A6F65_01320	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A6F65_01321	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A6F65_01322	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A6F65_01323	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A6F65_01324	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A6F65_01325	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A6F65_01326	ENOG41084HQ	50S ribosomal protein L30
A6F65_01328	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A6F65_01329	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A6F65_01330	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A6F65_01333	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A6F65_01334	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A6F65_01335	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6F65_01336	ENOG4108ZT0	50S ribosomal protein l17
A6F65_01340	ENOG4105EN6	Membrane
A6F65_01343	ENOG4107QN2	dihydrolipoyl dehydrogenase
A6F65_01345	ENOG4105C7S	Dehydrogenase
A6F65_01346	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
A6F65_01349	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A6F65_01350	ENOG4105BZU	Histidine kinase
A6F65_01353	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A6F65_01355	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
A6F65_01356	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A6F65_01361	ENOG4107XID	2'-5' rna ligase
A6F65_01370	ENOG4105CDH	Citrulline--aspartate ligase
A6F65_01372	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
A6F65_01373	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
A6F65_01378	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A6F65_01379	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
A6F65_01382	ENOG4107S78	Band 7 protein
A6F65_01383	ENOG4108RRZ	Transcription elongation factor GreB
A6F65_01384	ENOG4107SC1	transglycosylase
A6F65_01385	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A6F65_01387	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
A6F65_01393	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
A6F65_01394	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A6F65_01397	ENOG4105CK7	Sodium proline symporter
A6F65_01398	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
A6F65_01404	ENOG4105CSU	acyl-Coa dehydrogenase
A6F65_01406	ENOG4105CHU	acetyl-coa acetyltransferase
A6F65_01407	ENOG4105CEY	Amp-dependent synthetase and ligase
A6F65_01408	ENOG4107SWG	transcriptional regulator MERR family
A6F65_01417	ENOG4105C4R	Atp-dependent dna helicase
A6F65_01421	ENOG4106H78	methyltransferase
A6F65_01424	ENOG4105EYM	Major Facilitator superfamily
A6F65_01425	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A6F65_01426	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
A6F65_01427	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
A6F65_01428	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
A6F65_01429	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A6F65_01430	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
A6F65_01432	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A6F65_01435	ENOG4105W5Q	DNA repair protein (RadC
A6F65_01440	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
A6F65_01441	ENOG4105VD1	ATP synthase subunit C
A6F65_01442	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A6F65_01443	ENOG4108733	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A6F65_01445	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A6F65_01446	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A6F65_01448	ENOG4105CAT	Cytidine monophosphate kinase
A6F65_01450	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
A6F65_01453	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A6F65_01454	ENOG4105K5M	30s ribosomal protein S16
A6F65_01455	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A6F65_01459	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
A6F65_01460	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A6F65_01464	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A6F65_01470	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6F65_01471	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6F65_01473	ENOG4105FYV	Amp nucleosidase
A6F65_01474	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A6F65_01475	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A6F65_01476	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
A6F65_01477	ENOG4105CKW	Inner membrane protein yedI
A6F65_01479	ENOG4105DFU	Cell wall formation (By similarity)
A6F65_01480	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
A6F65_01481	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A6F65_01485	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A6F65_01487	ENOG4105EQH	reductase
A6F65_01488	ENOG4105BZU	Histidine kinase
A6F65_01489	ENOG4105BZU	Histidine kinase
A6F65_01490	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A6F65_01495	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A6F65_01499	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A6F65_01501	ENOG4105EMU	Dehydrogenase
A6F65_01505	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A6F65_01507	ENOG4105CHR	reductase
A6F65_01508	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
A6F65_01510	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
A6F65_01516	ENOG4105CGZ	zinc metallopeptidase
A6F65_01521	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A6F65_01523	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
A6F65_01524	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A6F65_01525	ENOG4105DQU	oxidoreductase, subunit beta
A6F65_01527	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A6F65_01529	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
A6F65_01530	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A6F65_01535	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
A6F65_01537	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
A6F65_01538	ENOG4107R0V	Pyruvate dehydrogenase
A6F65_01539	ENOG4105CPP	Dehydrogenase, E1 component
A6F65_01540	ENOG4107QSN	dihydrolipoamide acetyltransferase
A6F65_01544	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
A6F65_01547	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A6F65_01549	ENOG4105BZA	Phosphoglycerate kinase
A6F65_01551	ENOG4105WYW	fructose-bisphosphate aldolase
A6F65_01553	ENOG4106HMZ	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A6F65_01554	ENOG4108QQZ	ErfK YbiS YcfS YnhG family protein
A6F65_01555	ENOG4105E4C	Lytic transglycosylase catalytic
A6F65_01557	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A6F65_01558	ENOG4105ECY	inositol monophosphatase
A6F65_01565	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6F65_01567	ENOG4105DHU	Bile acid
A6F65_01569	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A6F65_01570	ENOG4105C8J	)-transporter
A6F65_01572	ENOG4108UHE	carbonic anhydrase
A6F65_01574	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A6F65_01575	ENOG410829K	Lysine exporter protein (Lyse ygga)
A6F65_01577	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A6F65_01579	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A6F65_01581	ENOG4105C8U	phosphate abc transporter
A6F65_01583	ENOG4106MAR	Phosphate-selective porin O and P
A6F65_01584	ENOG4105BZU	Histidine kinase
A6F65_01586	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A6F65_01590	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A6F65_01591	ENOG4108YYC	ycei family
A6F65_01593	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
A6F65_01595	ENOG4108ZP8	Acetolactate synthase small subunit
A6F65_01596	ENOG4105C7K	acetolactate synthase
A6F65_01597	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
A6F65_01601	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
A6F65_01602	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A6F65_01603	ENOG4105CTB	Polyprenyl synthetase
A6F65_01604	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
A6F65_01605	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A6F65_01606	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
A6F65_01608	ENOG4105DA5	(ABC) transporter
A6F65_01609	ENOG4105E3A	(ABC) transporter
A6F65_01611	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A6F65_01613	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A6F65_01618	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
A6F65_01619	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A6F65_01620	ENOG4108YZG	isomerase
A6F65_01621	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6F65_01622	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A6F65_01627	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A6F65_01633	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A6F65_01634	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A6F65_01636	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
A6F65_01640	ENOG4105CNI	cell division protein FtsW
A6F65_01643	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
A6F65_01645	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
A6F65_01651	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A6F65_01652	ENOG4108Z1B	Cyclase dehydrase
A6F65_01655	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
A6F65_01657	ENOG4105CUX	Signal transduction histidine kinase
A6F65_01658	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6F65_01659	ENOG4105ES5	Histidine kinase
A6F65_01660	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6F65_01662	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A6F65_01663	ENOG4105DXN	mazG family
A6F65_01664	ENOG4105CWC	Acetylornithine deacetylase
A6F65_01666	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A6F65_01667	ENOG4105F8V	Hydrolase, tatD family
A6F65_01669	ENOG4107QRG	dna polymerase iii
A6F65_01670	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A6F65_01672	ENOG4105K6T	rare lipoprotein A
A6F65_01673	ENOG4105CVE	Lytic murein transglycosylase
A6F65_01682	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A6F65_01683	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
A6F65_01685	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A6F65_01686	ENOG4105CSH	Transporter
A6F65_01688	ENOG4105E96	Colicin v production protein
A6F65_01692	ENOG4105CFG	Acts as a chaperone (By similarity)
A6F65_01697	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A6F65_01698	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
A6F65_01699	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A6F65_01700	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A6F65_01702	ENOG4105CSA	Coproporphyrinogen iii oxidase
A6F65_01703	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A6F65_01704	ENOG4107T5V	SNARE associated Golgi
A6F65_01705	ENOG4105D7Z	glutathione synthase
A6F65_01706	ENOG41082FP	UPF0102 protein
A6F65_01707	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A6F65_01708	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
A6F65_01709	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6F65_01715	ENOG4105EHZ	conserved protein UCP016719
A6F65_01717	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A6F65_01721	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A6F65_01724	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A6F65_01725	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
A6F65_01726	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
A6F65_01732	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
A6F65_01733	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
A6F65_01734	ENOG4105C3G	gtp-binding protein
A6F65_01740	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
A6F65_01753	ENOG4105KWW	Biogenesis protein
A6F65_01754	ENOG4107QX9	Thiol disulfide interChange protein
A6F65_01755	ENOG4105DA4	cytochrome c-type biogenesis protein
A6F65_01756	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
A6F65_01758	ENOG41060IM	Heme exporter protein
A6F65_01764	ENOG4108ZNX	Heat shock protein
A6F65_01765	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A6F65_01767	ENOG4105CP7	Triose-phosphate isomerase
A6F65_01769	ENOG4105CRQ	synthase (Component I)
A6F65_01773	ENOG4105DDQ	anthranilate synthase
A6F65_01774	ENOG4108I0Q	anthranilate phosphoribosyltransferase
A6F65_01775	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A6F65_01776	ENOG4108Z7R	Chaperone CsaA
A6F65_01777	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A6F65_01778	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A6F65_01779	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A6F65_01780	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
A6F65_01781	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A6F65_01782	ENOG4105BZN	citrate synthase
A6F65_01784	ENOG4105BZU	Histidine kinase
A6F65_01791	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
A6F65_01792	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A6F65_01793	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A6F65_01794	ENOG4105C8S	subunit m
A6F65_01795	ENOG4105D65	subunit l
A6F65_01796	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A6F65_01797	ENOG4105DF2	NADH dehydrogenase subunit j
A6F65_01798	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A6F65_01799	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
A6F65_01801	ENOG4107R0R	NADH dehydrogenase subunit g
A6F65_01806	ENOG4107QIZ	NADH dehydrogenase
A6F65_01810	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A6F65_01812	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A6F65_01813	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A6F65_01814	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A6F65_01815	ENOG4107RGH	Aldehyde dehydrogenase
A6F65_01816	ENOG4105CHU	acetyl-coa acetyltransferase
A6F65_01819	ENOG4105BZU	Histidine kinase
A6F65_01821	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
A6F65_01822	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A6F65_01823	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A6F65_01824	ENOG4108JQC	penicillin-binding protein 1A
A6F65_01825	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A6F65_01826	ENOG4105C03	ribonuclease
A6F65_01830	ENOG4105K64	Glycosyl transferase, family 2
A6F65_01833	ENOG4105D6Z	AFG1 family ATPase
A6F65_01834	ENOG4105C2I	pirin domain protein
A6F65_01835	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A6F65_01847	ENOG4105CEY	Amp-dependent synthetase and ligase
A6F65_01854	ENOG4105C01	Dihydroxy-acid dehydratase
A6F65_01856	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
A6F65_01857	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
A6F65_01860	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
A6F65_01861	ENOG4105FEU	K -dependent Na -Ca exchanger
A6F65_01863	ENOG4105CEY	Amp-dependent synthetase and ligase
A6F65_01864	ENOG4105C0B	DNA polymerase III (alpha subunit)
A6F65_01866	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A6F65_01867	ENOG4105D60	lipoprotein releasing system transmembrane protein
A6F65_01868	ENOG4105BZU	Histidine kinase
A6F65_01869	ENOG4105CB5	ATP-dependent DNA helicase recG
A6F65_01872	ENOG4105BZU	Histidine kinase
A6F65_01875	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A6F65_01881	ENOG4107TK4	histidinol-phosphate phosphatase
A6F65_01882	ENOG4105K63	Thioredoxin
A6F65_01885	ENOG4108S0S	Nucleotidyl transferase
A6F65_01886	ENOG4105EHM	Aminoglycoside phosphotransferase
A6F65_01887	ENOG4108097	ATP-binding protein
A6F65_01888	ENOG4105I8F	Histidine kinase
A6F65_01889	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A6F65_01893	ENOG4108RZE	Tetr family transcriptional regulator
A6F65_01894	ENOG4105EUJ	GTP cyclohydrolase i
A6F65_01895	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A6F65_01902	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
A6F65_01903	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A6F65_01906	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A6F65_01910	ENOG4107QP8	phosphohexose isomerase
A6F65_01911	ENOG4105C3F	Signal peptidase i
A6F65_01913	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
A6F65_01920	ENOG4105C79	DNA protecting protein DprA
A6F65_01921	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
A6F65_01922	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A6F65_01923	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A6F65_01924	ENOG4105BZU	Histidine kinase
A6F65_01926	ENOG4105E0R	Deoxyhypusine synthase
A6F65_01930	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A6F65_01932	ENOG4105BZP	glycoside hydrolase 15-related
A6F65_01933	ENOG4108K4C	ec 3.1.3.12
A6F65_01937	ENOG4105HHA	aminodeoxychorismate lyase
A6F65_01938	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A6F65_01939	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A6F65_01941	ENOG4105C9M	aspartyl-trna synthetase
A6F65_01943	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
A6F65_01944	ENOG4105C5Q	Transcriptional regulator
A6F65_01947	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
A6F65_01949	ENOG4105C7K	acetolactate synthase
A6F65_01951	ENOG4105BZU	Histidine kinase
A6F65_01952	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
A6F65_01953	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A6F65_01954	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A6F65_01955	ENOG4107835	probably involved in intracellular septation (By similarity)
A6F65_01956	ENOG4105DFH	Transport of potassium into the cell (By similarity)
A6F65_01961	ENOG41082FS	50S ribosomal protein L31
A6F65_01962	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
A6F65_01965	ENOG4105DZP	Membrane-associated zinc metalloprotease
A6F65_01969	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A6F65_01970	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A6F65_01973	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A6F65_01974	ENOG4105CE9	30S ribosomal protein S2
A6F65_01976	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
A6F65_01978	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A6F65_01981	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A6F65_01983	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A6F65_01984	ENOG4107QMP	dna polymerase iii subunits gamma and tau
A6F65_01986	ENOG4105CQ7	ATP-dependent helicase
A6F65_01987	ENOG4105EAH	synthase
A6F65_01988	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
A6F65_01989	ENOG410903D	sensor protein
A6F65_01990	ENOG41074H6	response regulator
A6F65_01992	ENOG4105IFJ	Histidine kinase
A6F65_01993	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A6F65_01995	ENOG4105MPN	Membrane
A6F65_01996	ENOG4105C5H	ABC transporter
A6F65_02003	ENOG4105JNK	Glycosyl transferase (Group 1
A6F65_02004	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A6F65_02005	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A6F65_02009	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A6F65_02010	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
A6F65_02011	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A6F65_02014	ENOG4105F7P	transcriptional regulator AsnC family
A6F65_02015	ENOG4105BZU	Histidine kinase
A6F65_02019	ENOG4107R73	Mate efflux family protein
A6F65_02022	ENOG4105IIU	Aminopeptidase
A6F65_02030	ENOG4105DK7	lysyl-tRNA synthetase
A6F65_02031	ENOG4105D64	Mechanosensitive ion channel
A6F65_02032	ENOG4105DVT	helicase
A6F65_02034	ENOG4105WJX	transcriptional regulator MERR family
A6F65_02035	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A6F65_02036	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A6F65_02037	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
A6F65_02038	ENOG41067VY	50S ribosomal protein L32
A6F65_02040	ENOG4105C5X	domain protein
A6F65_02041	ENOG4108UVJ	appr-1-p processing domain protein
A6F65_02046	ENOG4105C8N	cysteinyl-tRNA synthetase
A6F65_02048	ENOG4105C8N	cysteinyl-tRNA synthetase
A6F65_02053	ENOG4105C25	Primosomal protein n'
A6F65_02055	ENOG4105SYT	Methylenetetrahydrofolate reductase
A6F65_02056	ENOG4105C3R	Methionine synthase
A6F65_02057	ENOG4105C3R	Methionine synthase
A6F65_02058	ENOG4105KVH	Transcriptional regulator
A6F65_02059	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
A6F65_02060	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
A6F65_02062	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A6F65_02069	ENOG4105CNG	UPF0061 protein
A6F65_02070	ENOG4105C26	Dehydrogenase
A6F65_02073	ENOG4105FR1	rard protein
A6F65_02074	ENOG4105EKE	dihydroorotase
A6F65_02076	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
A6F65_02079	ENOG4107ZSV	Receptor
A6F65_02081	ENOG4107QPR	SAICAR synthetase
A6F65_02082	ENOG4107RAN	Peptidase, M16
A6F65_02084	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
A6F65_02085	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
A6F65_02089	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A6F65_02092	ENOG4105D7W	serine acetyltransferase
A6F65_02095	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A6F65_02096	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A6F65_02098	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A6F65_02101	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A6F65_02102	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
A6F65_02103	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
A6F65_02104	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
A6F65_02105	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A6F65_02107	ENOG4105F4X	arginine
A6F65_02108	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
A6F65_02111	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
A6F65_02114	ENOG4105HA9	of methanol dehydrogenase type
A6F65_02116	ENOG4108YZ4	nudix hydrolase
A6F65_02120	ENOG4105D9N	nucleoside
A6F65_02122	ENOG4105DNH	Major Facilitator
A6F65_02123	ENOG4105C26	Dehydrogenase
A6F65_02125	ENOG4105CHR	reductase
A6F65_02127	ENOG4105CI2	imidazolone-5-propionate hydrolase
A6F65_02137	ENOG4105IKQ	hydratase
A6F65_02145	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
A6F65_02150	ENOG4105DVW	rieske (2Fe-2S)
A6F65_02154	ENOG4108UYE	Lactoylglutathione lyase
A6F65_02155	ENOG4105CQB	FAD linked oxidase domain protein
A6F65_02175	ENOG4105E3A	(ABC) transporter
A6F65_02178	ENOG4105DQ4	alcohol dehydrogenase
A6F65_02181	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A6F65_02182	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A6F65_02183	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A6F65_02184	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
A6F65_02185	ENOG4108Z4T	Peptidase M50
A6F65_02186	ENOG4107104	thymidine kinase
A6F65_02188	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A6F65_02192	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
A6F65_02194	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
A6F65_02198	ENOG4105E51	psp operon transcriptional activator
A6F65_02200	ENOG41087YS	Phage shock protein A
A6F65_02206	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
A6F65_02207	ENOG4105VPI	YqaE family transport protein
A6F65_02211	ENOG4108TGP	Thioesterase superfamily protein
A6F65_02216	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A6F65_02218	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A6F65_02222	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A6F65_02224	ENOG4108I0Y	(ABC) transporter
A6F65_02227	ENOG4105D05	Receptor
A6F65_02229	ENOG41082BM	Transcriptional regulator, arsr family
A6F65_02232	ENOG4105D1H	recombination factor protein RarA
A6F65_02235	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A6F65_02236	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
A6F65_02238	ENOG4105KHC	sulfurtransferase
A6F65_02239	ENOG4105C28	cystathionine
A6F65_02240	ENOG4105D64	Mechanosensitive ion channel
A6F65_02241	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A6F65_02243	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
A6F65_02245	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
A6F65_02247	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
A6F65_02248	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A6F65_02249	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A6F65_02251	ENOG4105HFZ	Membrane
A6F65_02252	ENOG4105II7	pyrroline-5-carboxylate reductase
A6F65_02255	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A6F65_02256	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A6F65_02257	ENOG4108UFP	Essential cell division protein (By similarity)
A6F65_02258	ENOG4105CPF	Cell wall formation (By similarity)
A6F65_02259	ENOG4105D4A	Cell wall formation (By similarity)
A6F65_02260	ENOG4105DFU	Cell wall formation (By similarity)
A6F65_02261	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A6F65_02263	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A6F65_02264	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A6F65_02269	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A6F65_02270	ENOG4107YUR	Cell division protein mraZ
A6F65_02273	ENOG4105C6T	cysteine synthase
A6F65_02277	ENOG4105CHR	reductase
A6F65_02279	ENOG4105KZX	Pterin carbinolamine dehydratase
A6F65_02280	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
A6F65_02281	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
A6F65_02282	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A6F65_02284	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A6F65_02286	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A6F65_02287	ENOG4108YZA	Nitrogen regulatory protein pii
A6F65_02288	ENOG4105C5F	glutamine synthetase
A6F65_02290	ENOG4105VZ8	Transcriptional regulator
A6F65_02296	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
A6F65_02297	ENOG4105C7B	Threonine dehydratase
A6F65_02298	ENOG4105EFZ	amidohydrolase
A6F65_02299	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A6F65_02301	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A6F65_02302	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
A6F65_02303	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
A6F65_02304	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
A6F65_02306	ENOG4105C75	arginyL-tRNA synthetase
A6F65_02308	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
A6F65_02309	ENOG4105CUV	Homoserine Kinase
A6F65_02310	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A6F65_02311	ENOG4106178	UPF0339 protein
A6F65_02312	ENOG4105FC8	fad dependent oxidoreductase
A6F65_02322	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
A6F65_02332	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A6F65_02335	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A6F65_02336	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A6F65_02339	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A6F65_02340	ENOG4105K5G	30S ribosomal protein S21
A6F65_02341	ENOG41082CG	Protein CrcB homolog
A6F65_02342	ENOG4105EI2	Pseudouridine synthase
A6F65_02343	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A6F65_02348	ENOG4105DHJ	ABC, transporter
A6F65_02349	ENOG4105CY3	ABC transporter, permease
A6F65_02350	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A6F65_02352	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A6F65_02358	ENOG410802X	bacteriophage n4 adsorption protein b
A6F65_02359	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A6F65_02362	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
A6F65_02363	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
A6F65_02368	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
A6F65_02369	ENOG4105PGM	cation diffusion facilitator family transporter
A6F65_02370	ENOG4105K6V	RNA polymerase
A6F65_02376	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A6F65_02377	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A6F65_02379	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A6F65_02381	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A6F65_02386	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A6F65_02389	ENOG4108UQY	Iron-storage protein
A6F65_02391	ENOG4105DHF	Membrane
A6F65_02393	ENOG4107QJE	Chromosome Partitioning Protein
A6F65_02396	ENOG4105CD3	dihydroorotase
A6F65_02397	ENOG4105CXT	aspartate transcarbamylase
A6F65_02398	ENOG4105D07	Signal peptide peptidase, SppA
A6F65_02401	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A6F65_02402	ENOG4105Q84	sucrose synthase
A6F65_02408	ENOG4105EIG	urea carboxylase-associated protein 1
A6F65_02415	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A6F65_02421	ENOG4107QMH	DNA methylase
A6F65_02427	ENOG4108VB1	regulatoR
A6F65_02430	ENOG4105CJW	magnesium transporter
A6F65_02431	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
A6F65_02432	ENOG4105F8J	Adenylate Guanylate cyclase
A6F65_02434	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
A6F65_02436	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A6F65_02437	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A6F65_02438	ENOG4108K5P	(LipO)protein
A6F65_02441	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
A6F65_02452	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A6F65_02455	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
A6F65_02459	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A6F65_02466	ENOG4105EXU	Membrane
A6F65_02467	ENOG4105EXU	Membrane
A6F65_02472	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A6F65_02476	ENOG4108ESX	Receptor
A6F65_02477	ENOG4108XHQ	(2Fe-2S)-binding domain protein
A6F65_02479	ENOG4105C26	Dehydrogenase
A6F65_02480	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
A6F65_02481	ENOG4105E0C	molybdate abc transporter
A6F65_02482	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
A6F65_02483	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
A6F65_02484	ENOG4105C9X	ppx gppa phosphatase
A6F65_02486	ENOG4105QV4	Tryptophan halogenase
A6F65_02489	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A6F65_02490	ENOG4105CHM	Aminotransferase
A6F65_02491	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
A6F65_02493	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
A6F65_02500	ENOG41074H6	response regulator
A6F65_02501	ENOG4105BZU	Histidine kinase
A6F65_02505	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A6F65_02507	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A6F65_02508	ENOG4105DWF	phosphomethylpyrimidine kinase
A6F65_02509	ENOG4108URH	decarboxylase
A6F65_02512	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
A6F65_02513	ENOG4105G9V	cytochrome C
A6F65_02514	ENOG4105CQC	Prephenate dehydratase
A6F65_02517	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A6F65_02521	ENOG4108HF7	Gcn5-related n-acetyltransferase
A6F65_02527	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
A6F65_02530	ENOG4105DGU	Histone deacetylase
A6F65_02533	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
A6F65_02536	ENOG4108I0Z	Aconitate hydratase
A6F65_02537	ENOG4107YZP	Rhodanese domain protein
A6F65_02540	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A6F65_02541	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A6F65_02542	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
A6F65_02549	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
A6F65_02550	ENOG4105CJR	Integral membrane protein (MviN
A6F65_02551	ENOG4105C31	Tryptophanyl-tRNA synthetase
A6F65_02555	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
A6F65_02556	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A6F65_02560	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
A6F65_02562	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)