locus-tag	class	description
AEB_P0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AEB_P0004	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AEB_P0005	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AEB_P0007	COG1301	dicarboxylic acid transport
AEB_P0008	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AEB_P0009	COG0625	glutathione transferase activity
AEB_P0013	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AEB_P0014	COG0706	membrane insertase activity
AEB_P0015	COG0594	ribonuclease P activity
AEB_P0016	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AEB_P0025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AEB_P0040	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AEB_P0043	COG2866	Carboxypeptidase
AEB_P0045	COG0753	catalase activity
AEB_P0051	COG5328	Belongs to the UPF0262 family
AEB_P0052	COG0305	Participates in initiation and elongation during chromosome replication
AEB_P0054	COG1758	RNA polymerase activity
AEB_P0055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEB_P0056	COG2894	cell division
AEB_P0063	COG1482	cell wall glycoprotein biosynthetic process
AEB_P0069	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AEB_P0084	COG0489	protein tyrosine kinase activity
AEB_P0084	COG3206	protein involved in exopolysaccharide biosynthesis
AEB_P0088	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AEB_P0094	COG1045	serine acetyltransferase
AEB_P0095	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AEB_P0095	COG2755	lipolytic protein G-D-S-L family
AEB_P0099	COG0673	inositol 2-dehydrogenase activity
AEB_P0100	COG0730	response to heat
AEB_P0101	COG1218	3'(2'),5'-bisphosphate nucleotidase
AEB_P0103	COG0175	sulfate reduction
AEB_P0108	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
AEB_P0109	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEB_P0110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEB_P0110	COG3453	Protein conserved in bacteria
AEB_P0111	COG0450	alkyl hydroperoxide reductase
AEB_P0112	COG0640	Transcriptional regulator
AEB_P0116	COG0446	pyridine nucleotide-disulphide oxidoreductase
AEB_P0120	COG5001	Diguanylate cyclase
AEB_P0120	COG3447	MASE1 domain protein
AEB_P0120	COG5002	protein histidine kinase activity
AEB_P0121	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AEB_P0122	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AEB_P0123	COG4988	ABC transporter
AEB_P0125	COG1294	oxidase, subunit
AEB_P0129	COG4771	TonB-dependent receptor
AEB_P0134	COG1609	Transcriptional regulator
AEB_P0137	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AEB_P0138	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AEB_P0141	COG2188	Transcriptional regulator
AEB_P0144	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AEB_P0147	COG1414	Transcriptional regulator
AEB_P0148	COG4771	TonB-dependent receptor
AEB_P0151	COG0402	S-adenosylhomocysteine deaminase activity
AEB_P0152	COG4771	TonB-dependent receptor
AEB_P0164	COG0384	phenazine biosynthesis protein PhzF
AEB_P0170	COG0596	Alpha beta hydrolase
AEB_P0172	COG2318	DinB family
AEB_P0185	COG0582	viral genome integration into host DNA
AEB_P0186	COG0702	epimerase
AEB_P0187	COG2133	pyrroloquinoline quinone binding
AEB_P0191	COG3618	amidohydrolase
AEB_P0193	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AEB_P0193	COG1372	Participates in initiation and elongation during chromosome replication
AEB_P0196	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AEB_P0196	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AEB_P0198	COG2827	Endonuclease containing a URI domain
AEB_P0200	COG1131	(ABC) transporter
AEB_P0207	COG0469	pyruvate kinase activity
AEB_P0209	COG3750	Belongs to the UPF0335 family
AEB_P0210	COG0393	Putative heavy-metal-binding
AEB_P0211	COG0217	transcriptional regulatory protein
AEB_P0212	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AEB_P0214	COG1393	Belongs to the ArsC family
AEB_P0215	COG3781	membrane
AEB_P0216	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AEB_P0217	COG0527	aspartate kinase activity
AEB_P0219	COG1012	belongs to the aldehyde dehydrogenase family
AEB_P0221	COG2119	membrane
AEB_P0223	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AEB_P0225	COG2175	clavaminate synthase activity
AEB_P0226	COG1063	alcohol dehydrogenase
AEB_P0230	COG1012	belongs to the aldehyde dehydrogenase family
AEB_P0231	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AEB_P0245	COG2159	amidohydrolase
AEB_P0247	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AEB_P0258	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AEB_P0261	COG2095	MarC family integral membrane protein
AEB_P0262	COG3920	Histidine kinase
AEB_P0265	COG3118	belongs to the thioredoxin family
AEB_P0270	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P0272	COG0519	Catalyzes the synthesis of GMP from XMP
AEB_P0272	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AEB_P0275	COG0187	DNA topoisomerase II activity
AEB_P0277	COG0129	dihydroxy-acid dehydratase activity
AEB_P0278	COG0445	tRNA wobble uridine modification
AEB_P0283	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AEB_P0286	COG1960	acyl-CoA dehydrogenase activity
AEB_P0288	COG0517	IMP dehydrogenase activity
AEB_P0288	COG1125	glycine betaine transport
AEB_P0289	COG1174	glycine betaine transport
AEB_P0291	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AEB_P0292	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AEB_P0296	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AEB_P0298	COG1674	ftsk spoiiie
AEB_P0301	COG4771	TonB-dependent receptor
AEB_P0304	COG0686	Belongs to the AlaDH PNT family
AEB_P0305	COG3706	GGDEF domain
AEB_P0305	COG0745	RESPONSE REGULATOR receiver
AEB_P0311	COG0745	RESPONSE REGULATOR receiver
AEB_P0312	COG2205	protein histidine kinase activity
AEB_P0314	COG0433	COG0433 Predicted ATPase
AEB_P0317	COG0564	pseudouridine synthase activity
AEB_P0319	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AEB_P0328	COG3186	Phenylalanine-4-hydroxylase
AEB_P0330	COG1968	undecaprenyl-diphosphatase activity
AEB_P0331	COG3590	peptidase
AEB_P0332	COG1132	(ABC) transporter
AEB_P0338	COG0070	glutamate synthase
AEB_P0338	COG0069	glutamate synthase activity
AEB_P0338	COG0067	glutamate synthase
AEB_P0342	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AEB_P0346	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AEB_P0348	COG2957	Belongs to the agmatine deiminase family
AEB_P0349	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AEB_P0350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AEB_P0351	COG2833	Protein of unknown function (DUF455)
AEB_P0352	COG0739	heme binding
AEB_P0357	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P0360	COG0495	leucyl-tRNA aminoacylation
AEB_P0365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AEB_P0366	COG2902	Dehydrogenase
AEB_P0368	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AEB_P0369	COG4152	abc transporter atp-binding protein
AEB_P0371	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEB_P0375	COG0776	regulation of translation
AEB_P0376	COG2188	Transcriptional regulator
AEB_P0377	COG3104	oligopeptide transport
AEB_P0378	COG1228	amidohydrolase
AEB_P0380	COG0545	Peptidyl-prolyl cis-trans isomerase
AEB_P0381	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AEB_P0383	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEB_P0392	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AEB_P0407	COG5489	Protein of unknown function (DUF736)
AEB_P0410	COG0776	regulation of translation
AEB_P0420	COG0741	lytic transglycosylase activity
AEB_P0424	COG4962	Type ii secretion system protein e
AEB_P0427	COG3451	type IV secretory pathway VirB4
AEB_P0437	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AEB_P0437	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AEB_P0438	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEB_P0439	COG0745	RESPONSE REGULATOR receiver
AEB_P0440	COG0642	Histidine kinase
AEB_P0441	COG0640	Transcriptional regulator
AEB_P0442	COG0450	alkyl hydroperoxide reductase
AEB_P0447	COG0730	response to heat
AEB_P0448	COG0450	alkyl hydroperoxide reductase
AEB_P0449	COG1271	oxidase subunit
AEB_P0450	COG1294	oxidase, subunit
AEB_P0452	COG2226	methyltransferase
AEB_P0455	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AEB_P0457	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEB_P0461	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AEB_P0462	COG1088	dTDP-glucose 4,6-dehydratase activity
AEB_P0463	COG1091	dTDP-4-dehydrorhamnose reductase activity
AEB_P0464	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AEB_P0472	COG0438	transferase activity, transferring glycosyl groups
AEB_P0472	COG1216	Glycosyl transferase, family 2
AEB_P0487	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AEB_P0488	COG2857	Cytochrome c1
AEB_P0488	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AEB_P0492	COG0308	aminopeptidase N
AEB_P0501	COG0588	phosphoglycerate mutase activity
AEB_P0503	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AEB_P0505	COG0196	riboflavin kinase activity
AEB_P0506	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AEB_P0507	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AEB_P0510	COG1253	flavin adenine dinucleotide binding
AEB_P0512	COG2885	chlorophyll binding
AEB_P0513	COG1218	3'(2'),5'-bisphosphate nucleotidase
AEB_P0514	COG0045	succinate-CoA ligase (ADP-forming) activity
AEB_P0516	COG2086	electron transfer activity
AEB_P0520	COG2733	membrane
AEB_P0522	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEB_P0526	COG0482	sulfurtransferase activity
AEB_P0531	COG0259	pyridoxamine-phosphate oxidase activity
AEB_P0532	COG0484	heat shock protein binding
AEB_P0533	COG1295	ribonuclease BN
AEB_P0534	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AEB_P0536	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AEB_P0543	COG0793	Belongs to the peptidase S41A family
AEB_P0545	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AEB_P0546	COG0799	negative regulation of ribosome biogenesis
AEB_P0547	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AEB_P0548	COG0667	Aldo Keto reductase
AEB_P0549	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AEB_P0550	COG0739	heme binding
AEB_P0553	COG0438	transferase activity, transferring glycosyl groups
AEB_P0556	COG0604	alcohol dehydrogenase
AEB_P0559	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AEB_P0559	COG1793	dna ligase
AEB_P0561	COG1872	DUF167
AEB_P0562	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AEB_P0564	COG0113	porphobilinogen synthase activity
AEB_P0565	COG0739	heme binding
AEB_P0570	COG1329	Transcriptional regulator
AEB_P0576	COG1956	GAF domain-containing protein
AEB_P0578	COG1475	DNA binding
AEB_P0579	COG1192	Involved in chromosome partitioning
AEB_P0580	COG0357	Ribosomal RNA small subunit methyltransferase G
AEB_P0581	COG0445	tRNA wobble uridine modification
AEB_P0582	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AEB_P0585	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AEB_P0587	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AEB_P0589	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AEB_P0590	COG0424	maF-like protein
AEB_P0591	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AEB_P0592	COG0237	dephospho-CoA kinase activity
AEB_P0594	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AEB_P0595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AEB_P0596	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AEB_P0602	COG0517	IMP dehydrogenase activity
AEB_P0607	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AEB_P0608	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AEB_P0608	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AEB_P0609	COG2972	Histidine kinase
AEB_P0615	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AEB_P0616	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AEB_P0618	COG1612	heme a metabolic process
AEB_P0620	COG2022	thiamine diphosphate biosynthetic process
AEB_P0622	COG1022	Amp-dependent synthetase and ligase
AEB_P0623	COG0405	Gamma-glutamyltransferase
AEB_P0624	COG0167	dihydroorotate dehydrogenase activity
AEB_P0625	COG1959	2 iron, 2 sulfur cluster binding
AEB_P0626	COG0719	Fe-S assembly protein
AEB_P0628	COG0396	ATPase activity
AEB_P0629	COG0719	Fe-S assembly protein
AEB_P0631	COG2151	metal-sulfur cluster biosynthetic enzyme
AEB_P0632	COG0316	Belongs to the HesB IscA family
AEB_P0637	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AEB_P0638	COG0151	Belongs to the GarS family
AEB_P0639	COG1570	exodeoxyribonuclease VII activity
AEB_P0643	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AEB_P0644	COG0590	tRNA wobble adenosine to inosine editing
AEB_P0649	COG3275	phosphorelay sensor kinase activity
AEB_P0651	COG0501	Belongs to the peptidase M48B family
AEB_P0662	COG2205	protein histidine kinase activity
AEB_P0664	COG0659	secondary active sulfate transmembrane transporter activity
AEB_P0667	COG4251	negative regulation of phosphorylation
AEB_P0668	COG4774	siderophore transport
AEB_P0670	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AEB_P0671	COG1192	Involved in chromosome partitioning
AEB_P0680	COG0517	IMP dehydrogenase activity
AEB_P0680	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AEB_P0681	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AEB_P0686	COG3665	Urea carboxylase-associated protein
AEB_P0688	COG1201	RNA secondary structure unwinding
AEB_P0696	COG1494	fructose-1,6-bisphosphatase
AEB_P0701	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AEB_P0702	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AEB_P0704	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AEB_P0705	COG0072	phenylalanine-tRNA ligase activity
AEB_P0709	COG0347	Belongs to the P(II) protein family
AEB_P0710	COG0004	ammonium transporteR
AEB_P0711	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AEB_P0711	COG2885	chlorophyll binding
AEB_P0713	COG1253	flavin adenine dinucleotide binding
AEB_P0714	COG1278	Cold shock
AEB_P0715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AEB_P0716	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AEB_P0717	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AEB_P0719	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AEB_P0735	COG4695	Portal protein
AEB_P0740	COG0156	8-amino-7-oxononanoate synthase activity
AEB_P0741	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AEB_P0749	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AEB_P0753	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AEB_P0756	COG1250	3-hydroxyacyl-CoA dehydrogenase
AEB_P0759	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AEB_P0761	COG0281	malic enzyme
AEB_P0761	COG0280	phosphate acetyltransferase
AEB_P0767	COG1475	DNA binding
AEB_P0768	COG2226	methyltransferase
AEB_P0770	COG4227	nucleotidyltransferase activity
AEB_P0787	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AEB_P0795	COG0672	)-iron permease
AEB_P0799	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEB_P0810	COG2217	Heavy metal translocating P-type atpase
AEB_P0818	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AEB_P0819	COG0713	ATP synthesis coupled electron transport
AEB_P0821	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AEB_P0823	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEB_P0833	COG0741	lytic transglycosylase activity
AEB_P0845	COG4962	Type ii secretion system protein e
AEB_P0848	COG3451	type IV secretory pathway VirB4
AEB_P0852	COG3701	Conjugal transfer protein
AEB_P0854	COG2948	multi-organism process
AEB_P0860	COG4771	TonB-dependent receptor
AEB_P0865	COG2771	luxR family
AEB_P0868	COG1802	Transcriptional regulator
AEB_P0872	COG0640	Transcriptional regulator
AEB_P0877	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AEB_P0878	COG0745	RESPONSE REGULATOR receiver
AEB_P0879	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AEB_P0880	COG1137	ATPase activity
AEB_P0882	COG0668	transmembrane transport
AEB_P0883	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AEB_P0885	COG0124	histidyl-tRNA synthetase
AEB_P0886	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AEB_P0887	COG2890	protein-(glutamine-N5) methyltransferase activity
AEB_P0889	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AEB_P0890	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AEB_P0891	COG2311	Membrane
AEB_P0892	COG0477	Major facilitator Superfamily
AEB_P0896	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AEB_P0898	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AEB_P0898	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AEB_P0902	COG0459	protein refolding
AEB_P0903	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AEB_P0904	COG0534	Mate efflux family protein
AEB_P0906	COG0222	ribosome binding
AEB_P0907	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AEB_P0911	COG0085	RNA polymerase activity
AEB_P0912	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AEB_P0913	COG1902	pentaerythritol trinitrate reductase activity
AEB_P0914	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AEB_P0914	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AEB_P0917	COG0717	Belongs to the dCTP deaminase family
AEB_P0919	COG0028	Belongs to the TPP enzyme family
AEB_P0920	COG0643	Histidine kinase
AEB_P0920	COG2198	Histidine kinase
AEB_P0922	COG0745	RESPONSE REGULATOR receiver
AEB_P0923	COG2201	protein-glutamate methylesterase activity
AEB_P0924	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AEB_P0925	COG5001	Diguanylate cyclase
AEB_P0926	COG0840	transmembrane signaling receptor activity
AEB_P0928	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AEB_P0930	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AEB_P0931	COG1012	belongs to the aldehyde dehydrogenase family
AEB_P0932	COG3038	cytochrome b561
AEB_P0933	COG1741	Belongs to the pirin family
AEB_P0934	COG0668	transmembrane transport
AEB_P0935	COG4771	TonB-dependent receptor
AEB_P0936	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AEB_P0937	COG0346	lactoylglutathione lyase activity
AEB_P0944	COG0668	transmembrane transport
AEB_P0946	COG2884	Cell division ATP-binding protein ftsE
AEB_P0950	COG0287	Prephenate dehydrogenase
AEB_P0951	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AEB_P0952	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEB_P0953	COG2813	Specifically methylates the guanine in position
AEB_P0953	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEB_P0954	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AEB_P0956	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AEB_P0958	COG3383	formate dehydrogenase (NAD+) activity
AEB_P0962	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AEB_P0965	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AEB_P0975	COG2814	Major facilitator Superfamily
AEB_P0976	COG0702	epimerase
AEB_P0979	COG2271	Major facilitator Superfamily
AEB_P0984	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P0986	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AEB_P0991	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AEB_P0992	COG2267	carboxylic ester hydrolase activity
AEB_P0993	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AEB_P0994	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AEB_P0995	COG1546	Belongs to the CinA family
AEB_P0995	COG1058	Belongs to the CinA family
AEB_P0997	COG0081	regulation of translation
AEB_P0998	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AEB_P1003	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AEB_P1004	COG1115	amino acid carrier protein
AEB_P1006	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AEB_P1010	COG0318	PFAM AMP-dependent synthetase and ligase
AEB_P1016	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEB_P1020	COG2205	protein histidine kinase activity
AEB_P1021	COG0745	RESPONSE REGULATOR receiver
AEB_P1024	COG3706	GGDEF domain
AEB_P1025	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AEB_P1027	COG0457	Tetratricopeptide repeat
AEB_P1031	COG2111	Na H antiporter
AEB_P1031	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AEB_P1032	COG1006	Multisubunit Na H antiporter MnhC subunit
AEB_P1033	COG0651	ATP synthesis coupled electron transport
AEB_P1035	COG2212	antiporter activity
AEB_P1041	COG0583	DNA-binding transcription factor activity
AEB_P1042	COG1741	Belongs to the pirin family
AEB_P1047	COG0662	Cupin 2, conserved barrel domain protein
AEB_P1047	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AEB_P1051	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AEB_P1052	COG2010	Cytochrome c
AEB_P1052	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AEB_P1053	COG0489	protein tyrosine kinase activity
AEB_P1054	COG0330	HflC and HflK could
AEB_P1057	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AEB_P1058	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEB_P1060	COG1846	Transcriptional regulator
AEB_P1062	COG0477	Major facilitator Superfamily
AEB_P1068	COG2852	Protein conserved in bacteria
AEB_P1079	COG0248	Ppx GppA phosphatase
AEB_P1080	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AEB_P1081	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
AEB_P1085	COG3451	type IV secretory pathway VirB4
AEB_P1088	COG1196	nuclear chromosome segregation
AEB_P1088	COG0739	heme binding
AEB_P1088	COG0741	lytic transglycosylase activity
AEB_P1093	COG0745	RESPONSE REGULATOR receiver
AEB_P1097	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AEB_P1105	COG4993	Dehydrogenase
AEB_P1107	COG0307	riboflavin synthase, alpha
AEB_P1108	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEB_P1108	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEB_P1109	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AEB_P1110	COG0659	secondary active sulfate transmembrane transporter activity
AEB_P1113	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEB_P1116	COG3659	wide pore channel activity
AEB_P1117	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AEB_P1117	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AEB_P1118	COG1105	Belongs to the carbohydrate kinase PfkB family
AEB_P1119	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AEB_P1119	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AEB_P1120	COG1609	Transcriptional regulator
AEB_P1121	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AEB_P1122	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AEB_P1124	COG1448	Aminotransferase
AEB_P1128	COG2983	Belongs to the UPF0260 family
AEB_P1129	COG1999	signal sequence binding
AEB_P1135	COG0629	single-stranded DNA binding
AEB_P1136	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P1137	COG1733	regulation of RNA biosynthetic process
AEB_P1141	COG0583	DNA-binding transcription factor activity
AEB_P1148	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AEB_P1149	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AEB_P1153	COG5265	(ABC) transporter
AEB_P1159	COG2081	HI0933 family
AEB_P1161	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEB_P1163	COG0114	fumarate hydratase activity
AEB_P1168	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AEB_P1171	COG1024	Enoyl-CoA hydratase
AEB_P1180	COG2376	Dihydroxyacetone kinase
AEB_P1182	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AEB_P1185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AEB_P1186	COG1120	ATPase activity
AEB_P1194	COG2824	Alkylphosphonate utilization operon protein PhnA
AEB_P1198	COG4106	trans-aconitate 2-methyltransferase activity
AEB_P1205	COG0436	Aminotransferase
AEB_P1206	COG3243	poly(R)-hydroxyalkanoic acid synthase
AEB_P1208	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AEB_P1214	COG0784	Response regulator, receiver
AEB_P1216	COG1063	alcohol dehydrogenase
AEB_P1218	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P1221	COG4771	TonB-dependent receptor
AEB_P1222	COG4977	sequence-specific DNA binding
AEB_P1223	COG2271	Major facilitator Superfamily
AEB_P1225	COG0235	Class ii aldolase
AEB_P1226	COG2080	2 iron, 2 sulfur cluster binding
AEB_P1230	COG0321	lipoyl(octanoyl) transferase activity
AEB_P1234	COG4325	translation initiation factor activity
AEB_P1245	COG0037	tRNA processing
AEB_P1248	COG0800	Aldolase
AEB_P1249	COG0837	glucose binding
AEB_P1250	COG0129	dihydroxy-acid dehydratase activity
AEB_P1251	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AEB_P1253	COG0432	Pfam Uncharacterised protein family UPF0047
AEB_P1258	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEB_P1261	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AEB_P1262	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AEB_P1267	COG4206	TonB-dependent receptor
AEB_P1268	COG4251	negative regulation of phosphorylation
AEB_P1268	COG2203	Gaf domain
AEB_P1268	COG3706	GGDEF domain
AEB_P1268	COG5001	Diguanylate cyclase
AEB_P1270	COG3706	GGDEF domain
AEB_P1271	COG4566	intracellular signal transduction
AEB_P1273	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AEB_P1275	COG1684	flagellar biosynthetic protein fliR
AEB_P1276	COG1987	bacterial-type flagellum assembly
AEB_P1284	COG1157	protein secretion by the type III secretion system
AEB_P1286	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AEB_P1288	COG1677	Flagellar hook-basal body complex protein FliE
AEB_P1289	COG2204	response regulator
AEB_P1290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AEB_P1293	COG1360	Flagellar Motor Protein
AEB_P1295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AEB_P1296	COG1256	bacterial-type flagellum assembly
AEB_P1296	COG4786	Flagellar basal body rod
AEB_P1298	COG1706	bacterial-type flagellum-dependent cell motility
AEB_P1299	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AEB_P1300	COG4786	Flagellar basal body rod
AEB_P1302	COG4786	Flagellar basal body rod
AEB_P1304	COG1558	bacterial-type flagellum-dependent cell motility
AEB_P1306	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AEB_P1315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEB_P1319	COG0842	Transport permease protein
AEB_P1320	COG0842	Transport permease protein
AEB_P1321	COG1131	(ABC) transporter
AEB_P1323	COG1309	transcriptional regulator
AEB_P1324	COG0577	efflux transmembrane transporter activity
AEB_P1324	COG1136	(ABC) transporter
AEB_P1325	COG0577	efflux transmembrane transporter activity
AEB_P1325	COG1136	(ABC) transporter
AEB_P1326	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEB_P1328	COG1846	Transcriptional regulator
AEB_P1332	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AEB_P1334	COG3755	Protein conserved in bacteria
AEB_P1335	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AEB_P1342	COG0439	Biotin carboxylase
AEB_P1343	COG0511	ligase activity, forming carbon-carbon bonds
AEB_P1348	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AEB_P1352	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AEB_P1354	COG1024	Enoyl-CoA hydratase
AEB_P1355	COG1042	CoA-binding domain protein
AEB_P1355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AEB_P1355	COG0045	succinate-CoA ligase (ADP-forming) activity
AEB_P1357	COG1960	acyl-CoA dehydrogenase activity
AEB_P1363	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AEB_P1364	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AEB_P1365	COG0181	hydroxymethylbilane synthase activity
AEB_P1368	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AEB_P1371	COG0556	nucleotide-excision repair
AEB_P1373	COG2226	methyltransferase
AEB_P1373	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEB_P1373	COG0596	Alpha beta hydrolase
AEB_P1374	COG2308	Evidence 4 Homologs of previously reported genes of
AEB_P1380	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AEB_P1381	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AEB_P1382	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AEB_P1385	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AEB_P1387	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEB_P1388	COG0165	Argininosuccinate lyase
AEB_P1390	COG0019	diaminopimelate decarboxylase activity
AEB_P1391	COG1648	precorrin-2 dehydrogenase activity
AEB_P1391	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AEB_P1392	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AEB_P1394	COG0628	permease
AEB_P1395	COG0681	Belongs to the peptidase S26 family
AEB_P1396	COG0736	holo-[acyl-carrier-protein] synthase activity
AEB_P1397	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AEB_P1398	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AEB_P1400	COG1565	acr, cog1565
AEB_P1400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AEB_P1401	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AEB_P1402	COG0109	protoheme IX farnesyltransferase activity
AEB_P1404	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AEB_P1411	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AEB_P1413	COG0314	molybdopterin synthase activity
AEB_P1416	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AEB_P1417	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AEB_P1419	COG0354	folic acid binding
AEB_P1420	COG5001	Diguanylate cyclase
AEB_P1420	COG3706	GGDEF domain
AEB_P1420	COG4251	negative regulation of phosphorylation
AEB_P1420	COG2203	Gaf domain
AEB_P1422	COG0418	dihydroorotase activity
AEB_P1426	COG1012	belongs to the aldehyde dehydrogenase family
AEB_P1427	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AEB_P1431	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEB_P1433	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AEB_P1434	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AEB_P1437	COG0789	Transcriptional regulator
AEB_P1440	COG1196	nuclear chromosome segregation
AEB_P1441	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AEB_P1441	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AEB_P1446	COG1278	Cold shock
AEB_P1449	COG2816	NAD+ diphosphatase activity
AEB_P1456	COG2239	Acts as a magnesium transporter
AEB_P1457	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AEB_P1459	COG0583	DNA-binding transcription factor activity
AEB_P1460	COG1253	flavin adenine dinucleotide binding
AEB_P1461	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AEB_P1464	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEB_P1467	COG4957	zinc ion binding
AEB_P1471	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AEB_P1472	COG0612	Peptidase, M16
AEB_P1473	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AEB_P1474	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEB_P1475	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AEB_P1478	COG4771	TonB-dependent receptor
AEB_P1481	COG4774	siderophore transport
AEB_P1483	COG1477	protein flavinylation
AEB_P1492	COG2010	Cytochrome c
AEB_P1498	COG0625	glutathione transferase activity
AEB_P1500	COG0435	Glutathione S-transferase
AEB_P1505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AEB_P1508	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AEB_P1513	COG1381	Involved in DNA repair and RecF pathway recombination
AEB_P1514	COG0473	3-isopropylmalate dehydrogenase activity
AEB_P1519	COG3920	Histidine kinase
AEB_P1520	COG2967	ApaG domain
AEB_P1521	COG0210	DNA helicase
AEB_P1522	COG0742	ribosomal rna small subunit methyltransferase
AEB_P1523	COG1187	pseudouridine synthase activity
AEB_P1525	COG0285	dihydrofolate synthase activity
AEB_P1526	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AEB_P1527	COG0159	tryptophan synthase activity
AEB_P1528	COG2852	Protein conserved in bacteria
AEB_P1529	COG0133	tryptophan synthase activity
AEB_P1530	COG0135	phosphoribosylanthranilate isomerase activity
AEB_P1532	COG0284	orotidine-5'-phosphate decarboxylase activity
AEB_P1534	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AEB_P1538	COG2003	Belongs to the UPF0758 family
AEB_P1543	COG0356	it plays a direct role in the translocation of protons across the membrane
AEB_P1544	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AEB_P1545	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AEB_P1546	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AEB_P1548	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEB_P1551	COG0539	negative regulation of cytoplasmic translation
AEB_P1552	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AEB_P1553	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AEB_P1555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AEB_P1556	COG0228	four-way junction DNA binding
AEB_P1557	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AEB_P1559	COG0336	Belongs to the RNA methyltransferase TrmD family
AEB_P1560	COG0335	large ribosomal subunit rRNA binding
AEB_P1562	COG0531	amino acid
AEB_P1563	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AEB_P1568	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AEB_P1569	COG0359	binds to the 23S rRNA
AEB_P1570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AEB_P1571	COG0360	Binds together with S18 to 16S ribosomal RNA
AEB_P1573	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AEB_P1575	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AEB_P1578	COG0592	DNA-directed DNA polymerase activity
AEB_P1582	COG3300	MHYT domain
AEB_P1582	COG5001	Diguanylate cyclase
AEB_P1583	COG5001	Diguanylate cyclase
AEB_P1583	COG3300	MHYT domain
AEB_P1584	COG0481	GTPase activity
AEB_P1587	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEB_P1592	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AEB_P1594	COG1742	UPF0060 membrane protein
AEB_P1595	COG2264	protein methyltransferase activity
AEB_P1601	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AEB_P1606	COG2321	neutral zinc metallopeptidase
AEB_P1607	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P1609	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AEB_P1611	COG1051	belongs to the nudix hydrolase family
AEB_P1612	COG0674	pyruvate-flavodoxin oxidoreductase activity
AEB_P1612	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AEB_P1613	COG1013	pyruvate-flavodoxin oxidoreductase activity
AEB_P1615	COG0583	DNA-binding transcription factor activity
AEB_P1618	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AEB_P1620	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AEB_P1621	COG0049	tRNA binding
AEB_P1622	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AEB_P1623	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AEB_P1624	COG0051	transcription antitermination factor activity, RNA binding
AEB_P1625	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AEB_P1626	COG0088	Forms part of the polypeptide exit tunnel
AEB_P1627	COG0089	rRNA binding
AEB_P1628	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AEB_P1629	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AEB_P1630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AEB_P1631	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AEB_P1632	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AEB_P1633	COG0255	Belongs to the universal ribosomal protein uL29 family
AEB_P1634	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AEB_P1635	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AEB_P1636	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AEB_P1637	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AEB_P1638	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AEB_P1639	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AEB_P1640	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AEB_P1641	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AEB_P1642	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AEB_P1643	COG1841	ribosomal large subunit assembly
AEB_P1644	COG0200	Binds to the 23S rRNA
AEB_P1645	COG0201	protein transport
AEB_P1646	COG0563	adenylate kinase activity
AEB_P1647	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AEB_P1648	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AEB_P1649	COG0202	RNA polymerase activity
AEB_P1650	COG0203	ribosomal protein L17
AEB_P1651	COG1505	serine-type exopeptidase activity
AEB_P1654	COG2860	membrane
AEB_P1657	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AEB_P1658	COG0508	dehydrogenase complex catalyzes the overall conversion of
AEB_P1659	COG0567	Dehydrogenase, E1 component
AEB_P1660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AEB_P1662	COG0039	L-malate dehydrogenase activity
AEB_P1663	COG5001	Diguanylate cyclase
AEB_P1663	COG3300	MHYT domain
AEB_P1666	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AEB_P1669	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AEB_P1676	COG4771	TonB-dependent receptor
AEB_P1681	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P1685	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AEB_P1686	COG0137	argininosuccinate synthase activity
AEB_P1687	COG0534	Mate efflux family protein
AEB_P1688	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AEB_P1689	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AEB_P1696	COG3724	N-succinylarginine dihydrolase activity
AEB_P1701	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AEB_P1702	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AEB_P1703	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AEB_P1705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AEB_P1707	COG0105	UTP biosynthetic process
AEB_P1709	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AEB_P1710	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AEB_P1713	COG1045	serine acetyltransferase
AEB_P1715	COG0546	phosphoglycolate phosphatase activity
AEB_P1716	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AEB_P1717	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AEB_P1719	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AEB_P1720	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AEB_P1721	COG2080	2 iron, 2 sulfur cluster binding
AEB_P1722	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P1723	COG3387	PFAM Glycoside hydrolase 15-related
AEB_P1724	COG5001	Diguanylate cyclase
AEB_P1726	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AEB_P1727	COG1733	regulation of RNA biosynthetic process
AEB_P1729	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AEB_P1736	COG0741	lytic transglycosylase activity
AEB_P1737	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AEB_P1738	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AEB_P1743	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AEB_P1745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AEB_P1747	COG3153	acetyltransferase
AEB_P1747	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AEB_P1748	COG0538	isocitrate dehydrogenase activity
AEB_P1757	COG0513	Belongs to the DEAD box helicase family
AEB_P1759	COG0415	Belongs to the DNA photolyase family
AEB_P1760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AEB_P1762	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P1763	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AEB_P1779	COG2059	Chromate
AEB_P1786	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AEB_P1791	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AEB_P1795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AEB_P1797	COG0126	phosphoglycerate kinase activity
AEB_P1798	COG3588	fructose-bisphosphate aldolase
AEB_P1800	COG0352	thiamine-phosphate diphosphorylase activity
AEB_P1802	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AEB_P1803	COG0483	inositol monophosphate 1-phosphatase activity
AEB_P1804	COG3273	potassium ion transport
AEB_P1804	COG0471	metal ion transport
AEB_P1805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AEB_P1806	COG2205	protein histidine kinase activity
AEB_P1806	COG2198	Histidine kinase
AEB_P1806	COG0784	Response regulator, receiver
AEB_P1807	COG2204	response regulator
AEB_P1810	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AEB_P1811	COG0531	amino acid
AEB_P1814	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AEB_P1820	COG0745	RESPONSE REGULATOR receiver
AEB_P1821	COG0704	Plays a role in the regulation of phosphate uptake
AEB_P1822	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AEB_P1824	COG0573	inorganic phosphate transmembrane transporter activity
AEB_P1826	COG3746	phosphate-selective porin O and P
AEB_P1827	COG5002	protein histidine kinase activity
AEB_P1829	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AEB_P1834	COG0438	transferase activity, transferring glycosyl groups
AEB_P1835	COG0438	transferase activity, transferring glycosyl groups
AEB_P1837	COG0489	protein tyrosine kinase activity
AEB_P1837	COG3206	protein involved in exopolysaccharide biosynthesis
AEB_P1838	COG2197	response regulator
AEB_P1839	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AEB_P1844	COG2755	lipolytic protein G-D-S-L family
AEB_P1844	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AEB_P1846	COG1086	Polysaccharide biosynthesis protein
AEB_P1847	COG0438	transferase activity, transferring glycosyl groups
AEB_P1848	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AEB_P1848	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEB_P1849	COG2197	response regulator
AEB_P1850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AEB_P1851	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AEB_P1855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AEB_P1856	COG2353	YceI-like domain
AEB_P1857	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AEB_P1859	COG0028	Belongs to the TPP enzyme family
AEB_P1860	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AEB_P1861	COG0560	Phosphoserine phosphatase
AEB_P1862	COG2311	Membrane
AEB_P1863	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AEB_P1864	COG1722	exodeoxyribonuclease VII activity
AEB_P1865	COG0142	geranyltranstransferase activity
AEB_P1866	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AEB_P1867	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AEB_P1868	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AEB_P1869	COG1131	(ABC) transporter
AEB_P1870	COG0842	Transport permease protein
AEB_P1872	COG0343	queuine tRNA-ribosyltransferase activity
AEB_P1873	COG1012	belongs to the aldehyde dehydrogenase family
AEB_P1874	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AEB_P1876	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AEB_P1878	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AEB_P1879	COG0698	ribose 5-phosphate isomerase
AEB_P1881	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AEB_P1882	COG0358	DNA primase activity
AEB_P1884	COG0505	Belongs to the CarA family
AEB_P1888	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AEB_P1894	COG0148	phosphopyruvate hydratase activity
AEB_P1895	COG0667	Aldo Keto reductase
AEB_P1896	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AEB_P1898	COG1304	FMN binding
AEB_P1902	COG0437	4 iron, 4 sulfur cluster binding
AEB_P1909	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AEB_P1913	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AEB_P1917	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P1920	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AEB_P1926	COG2032	superoxide dismutase activity
AEB_P1927	COG1335	isochorismatase
AEB_P1928	COG2943	transferase activity, transferring hexosyl groups
AEB_P1929	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AEB_P1932	COG1295	ribonuclease BN
AEB_P1936	COG4771	TonB-dependent receptor
AEB_P1938	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEB_P1943	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEB_P1948	COG1260	myo-inositol-1-phosphate synthase
AEB_P1949	COG1063	alcohol dehydrogenase
AEB_P1950	COG0673	inositol 2-dehydrogenase activity
AEB_P1953	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P1954	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEB_P1956	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AEB_P1960	COG1877	trehalose-phosphatase activity
AEB_P1961	COG3387	PFAM Glycoside hydrolase 15-related
AEB_P1962	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AEB_P1969	COG3706	GGDEF domain
AEB_P1970	COG0156	8-amino-7-oxononanoate synthase activity
AEB_P1971	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AEB_P1972	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AEB_P1973	COG0758	DNA mediated transformation
AEB_P1974	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AEB_P1974	COG1754	DNA topoisomerase type I activity
AEB_P1976	COG2814	Major facilitator Superfamily
AEB_P1977	COG2885	chlorophyll binding
AEB_P1978	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AEB_P1979	COG0571	ribonuclease III activity
AEB_P1980	COG0681	Belongs to the peptidase S26 family
AEB_P1981	COG0166	Belongs to the GPI family
AEB_P1982	COG0513	Belongs to the DEAD box helicase family
AEB_P1984	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AEB_P1988	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AEB_P1989	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AEB_P1992	COG4974	Belongs to the 'phage' integrase family
AEB_P1993	COG0825	malonyl-CoA metabolic process
AEB_P1994	COG4783	chaperone-mediated protein folding
AEB_P1997	COG0494	nUDIX hydrolase
AEB_P1999	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEB_P2000	COG0302	gtp cyclohydrolase
AEB_P2002	COG0678	peroxiredoxin activity
AEB_P2002	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AEB_P2003	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AEB_P2004	COG2205	protein histidine kinase activity
AEB_P2005	COG0802	atpase or kinase
AEB_P2006	COG3178	'Phosphotransferase
AEB_P2007	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AEB_P2009	COG1074	ATP-dependent DNA helicase activity
AEB_P2011	COG0483	inositol monophosphate 1-phosphatase activity
AEB_P2012	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AEB_P2014	COG0653	protein targeting
AEB_P2016	COG2814	Major facilitator Superfamily
AEB_P2024	COG3750	Belongs to the UPF0335 family
AEB_P2069	COG0582	viral genome integration into host DNA
AEB_P2074	COG0582	viral genome integration into host DNA
AEB_P2075	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AEB_P2076	COG5001	Diguanylate cyclase
AEB_P2077	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AEB_P2079	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AEB_P2080	COG0488	(ABC) transporter
AEB_P2081	COG4591	ABC-type transport system involved in lipoprotein release permease component
AEB_P2082	COG1136	(ABC) transporter
AEB_P2084	COG0587	DNA-directed DNA polymerase activity
AEB_P2085	COG2885	chlorophyll binding
AEB_P2085	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AEB_P2087	COG0521	Mo-molybdopterin cofactor biosynthetic process
AEB_P2091	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AEB_P2093	COG0129	dihydroxy-acid dehydratase activity
AEB_P2095	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AEB_P2095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AEB_P2096	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AEB_P2101	COG0318	PFAM AMP-dependent synthetase and ligase
AEB_P2105	COG0489	protein tyrosine kinase activity
AEB_P2107	COG3267	Type II secretory pathway component ExeA
AEB_P2107	COG3409	Peptidoglycan-binding domain 1 protein
AEB_P2113	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AEB_P2117	COG0297	glycogen (starch) synthase activity
AEB_P2119	COG2244	polysaccharide biosynthetic process
AEB_P2121	COG1530	ribonuclease E activity
AEB_P2123	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AEB_P2124	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AEB_P2125	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AEB_P2126	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AEB_P2130	COG0183	Belongs to the thiolase family
AEB_P2131	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEB_P2132	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEB_P2133	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEB_P2134	COG0649	NAD binding
AEB_P2136	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AEB_P2139	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AEB_P2141	COG1034	ATP synthesis coupled electron transport
AEB_P2142	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AEB_P2144	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEB_P2146	COG0713	ATP synthesis coupled electron transport
AEB_P2149	COG1007	ATP synthesis coupled electron transport
AEB_P2151	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AEB_P2159	COG2205	protein histidine kinase activity
AEB_P2161	COG0372	Belongs to the citrate synthase family
AEB_P2162	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AEB_P2163	COG2333	competence protein COMEC
AEB_P2163	COG0658	competence protein
AEB_P2164	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AEB_P2165	COG0303	'Molybdopterin
AEB_P2166	COG0315	cyclic pyranopterin monophosphate synthase activity
AEB_P2167	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEB_P2169	COG0134	indole-3-glycerol-phosphate synthase activity
AEB_P2170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AEB_P2172	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AEB_P2174	COG0149	triose-phosphate isomerase activity
AEB_P2176	COG0504	CTP synthase activity
AEB_P2177	COG0071	Belongs to the small heat shock protein (HSP20) family
AEB_P2179	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AEB_P2183	COG3300	MHYT domain
AEB_P2183	COG5001	Diguanylate cyclase
AEB_P2186	COG4771	TonB-dependent receptor
AEB_P2191	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AEB_P2192	COG0508	dehydrogenase complex catalyzes the overall conversion of
AEB_P2192	COG0022	dehydrogenase e1 component
AEB_P2198	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AEB_P2200	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AEB_P2202	COG0012	GTP binding
AEB_P2204	COG0193	aminoacyl-tRNA hydrolase activity
AEB_P2205	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AEB_P2208	COG0752	glycyl-tRNA synthetase alpha subunit
AEB_P2209	COG0751	glycine-tRNA ligase activity
AEB_P2210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AEB_P2210	COG0574	Belongs to the PEP-utilizing enzyme family
AEB_P2212	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AEB_P2214	COG1960	acyl-CoA dehydrogenase activity
AEB_P2220	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AEB_P2222	COG3876	Protein conserved in bacteria
AEB_P2224	COG0840	transmembrane signaling receptor activity
AEB_P2226	COG0187	DNA topoisomerase II activity
AEB_P2228	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AEB_P2229	COG0792	nuclease activity
AEB_P2230	COG0189	ligase activity
AEB_P2231	COG0586	Pfam SNARE associated Golgi protein
AEB_P2232	COG4974	Belongs to the 'phage' integrase family
AEB_P2233	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEB_P2234	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AEB_P2235	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AEB_P2236	COG1420	regulation of RNA biosynthetic process
AEB_P2237	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AEB_P2241	COG0443	Heat shock 70 kDa protein
AEB_P2242	COG0484	heat shock protein binding
AEB_P2246	COG0477	Major facilitator Superfamily
AEB_P2247	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AEB_P2249	COG0442	prolyl-tRNA aminoacylation
AEB_P2250	COG2234	aminopeptidase activity
AEB_P2251	COG0557	exoribonuclease II activity
AEB_P2253	COG0508	dehydrogenase complex catalyzes the overall conversion of
AEB_P2255	COG1607	acyl-coa hydrolase
AEB_P2256	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AEB_P2259	COG2951	lytic endotransglycosylase activity
AEB_P2260	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AEB_P2261	COG1686	Belongs to the peptidase S11 family
AEB_P2262	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AEB_P2265	COG0084	hydrolase, TatD family'
AEB_P2266	COG0321	lipoyl(octanoyl) transferase activity
AEB_P2266	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AEB_P2268	COG5487	UPF0391 membrane protein
AEB_P2269	COG3956	TIGRFAM MazG family protein
AEB_P2270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AEB_P2271	COG1923	regulation of RNA biosynthetic process
AEB_P2272	COG2204	response regulator
AEB_P2273	COG5000	phosphorelay sensor kinase activity
AEB_P2274	COG2204	response regulator
AEB_P2275	COG3852	Histidine kinase
AEB_P2277	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AEB_P2277	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AEB_P2279	COG1546	Belongs to the CinA family
AEB_P2280	COG2867	negative regulation of translational initiation
AEB_P2281	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AEB_P2285	COG0678	peroxiredoxin activity
AEB_P2285	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AEB_P2287	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AEB_P2292	COG0772	Belongs to the SEDS family
AEB_P2306	COG4771	TonB-dependent receptor
AEB_P2312	COG1872	DUF167
AEB_P2313	COG2824	Alkylphosphonate utilization operon protein PhnA
AEB_P2323	COG4974	Belongs to the 'phage' integrase family
AEB_P2352	COG4957	zinc ion binding
AEB_P2361	COG4206	TonB-dependent receptor
AEB_P2399	COG0776	regulation of translation
AEB_P2402	COG2963	transposase activity
AEB_P2403	COG2801	Transposase and inactivated derivatives
AEB_P2407	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AEB_P2410	COG1012	belongs to the aldehyde dehydrogenase family
AEB_P2411	COG1024	Enoyl-CoA hydratase
AEB_P2411	COG1250	3-hydroxyacyl-CoA dehydrogenase
AEB_P2414	COG1012	belongs to the aldehyde dehydrogenase family
AEB_P2414	COG2030	dehydratase
AEB_P2415	COG1024	Enoyl-CoA hydratase
AEB_P2416	COG2050	protein possibly involved in aromatic compounds catabolism
AEB_P2417	COG0183	Belongs to the thiolase family
AEB_P2418	COG3396	Phenylacetate-CoA oxygenase
AEB_P2419	COG3460	Phenylacetate-CoA oxygenase
AEB_P2420	COG3396	Phenylacetate-CoA oxygenase
AEB_P2421	COG2151	metal-sulfur cluster biosynthetic enzyme
AEB_P2422	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AEB_P2425	COG4771	TonB-dependent receptor
AEB_P2426	COG0371	Dehydrogenase
AEB_P2429	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P2430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEB_P2431	COG0183	Belongs to the thiolase family
AEB_P2438	COG3485	protocatechuate 3,4-dioxygenase
AEB_P2443	COG0582	viral genome integration into host DNA
AEB_P2445	COG2963	transposase activity
AEB_P2446	COG3436	PFAM IS66 Orf2 family protein
AEB_P2447	COG4372	Transposase
AEB_P2451	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P2453	COG1250	3-hydroxyacyl-CoA dehydrogenase
AEB_P2456	COG1960	acyl-CoA dehydrogenase activity
AEB_P2461	COG1309	transcriptional regulator
AEB_P2462	COG1414	Transcriptional regulator
AEB_P2468	COG0431	NADPH-dependent FMN reductase
AEB_P2470	COG3384	dioxygenase
AEB_P2471	COG0400	carboxylic ester hydrolase activity
AEB_P2472	COG2259	Doxx family
AEB_P2478	COG1942	4-Oxalocrotonate Tautomerase
AEB_P2479	COG2267	carboxylic ester hydrolase activity
AEB_P2482	COG2963	transposase activity
AEB_P2483	COG2801	Transposase and inactivated derivatives
AEB_P2485	COG3713	MltA-interacting MipA family protein
AEB_P2486	COG0582	viral genome integration into host DNA
AEB_P2487	COG2801	Transposase and inactivated derivatives
AEB_P2508	COG0583	DNA-binding transcription factor activity
AEB_P2510	COG0445	tRNA wobble uridine modification
AEB_P2513	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEB_P2514	COG0583	DNA-binding transcription factor activity
AEB_P2515	COG4771	TonB-dependent receptor
AEB_P2523	COG1228	amidohydrolase
AEB_P2524	COG2986	histidine ammonia-lyase
AEB_P2526	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AEB_P2527	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AEB_P2531	COG4774	siderophore transport
AEB_P2531	COG1629	transport
AEB_P2533	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AEB_P2535	COG2205	protein histidine kinase activity
AEB_P2536	COG2814	Major facilitator Superfamily
AEB_P2537	COG0028	Belongs to the TPP enzyme family
AEB_P2542	COG1414	Transcriptional regulator
AEB_P2544	COG2222	sugar isomerase
AEB_P2547	COG3345	alpha-galactosidase
AEB_P2550	COG1349	DNA-binding transcription factor activity
AEB_P2555	COG4206	TonB-dependent receptor
AEB_P2556	COG0583	DNA-binding transcription factor activity
AEB_P2557	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEB_P2566	COG0583	DNA-binding transcription factor activity
AEB_P2567	COG0667	Aldo Keto reductase
AEB_P2569	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AEB_P2570	COG0366	Alpha amylase catalytic
AEB_P2572	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AEB_P2574	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AEB_P2575	COG1640	4-alpha-glucanotransferase
AEB_P2579	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AEB_P2580	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AEB_P2581	COG2205	protein histidine kinase activity
AEB_P2582	COG0745	RESPONSE REGULATOR receiver
AEB_P2583	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEB_P2585	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AEB_P2586	COG0784	Response regulator, receiver
AEB_P2587	COG0784	Response regulator, receiver
AEB_P2587	COG4191	Histidine kinase
AEB_P2610	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AEB_P2611	COG1136	(ABC) transporter
AEB_P2613	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEB_P2614	COG0450	alkyl hydroperoxide reductase
AEB_P2615	COG1294	oxidase, subunit
AEB_P2618	COG0446	pyridine nucleotide-disulphide oxidoreductase
AEB_P2623	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEB_P2625	COG2890	protein-(glutamine-N5) methyltransferase activity
AEB_P2633	COG1482	cell wall glycoprotein biosynthetic process
AEB_P2636	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AEB_P2637	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEB_P2640	COG1620	l-lactate permease
AEB_P2645	COG2217	Heavy metal translocating P-type atpase
AEB_P2646	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AEB_P2647	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AEB_P2648	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AEB_P2651	COG1937	Protein conserved in bacteria
AEB_P2653	COG2217	Heavy metal translocating P-type atpase
AEB_P2656	COG0670	Belongs to the BI1 family
AEB_P2661	COG0148	phosphopyruvate hydratase activity
AEB_P2662	COG0574	Belongs to the PEP-utilizing enzyme family
AEB_P2662	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AEB_P2664	COG0517	IMP dehydrogenase activity
AEB_P2665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AEB_P2666	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AEB_P2668	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEB_P2677	COG3920	Histidine kinase
AEB_P2680	COG0126	phosphoglycerate kinase activity
AEB_P2682	COG2132	Multicopper oxidase
AEB_P2683	COG1063	alcohol dehydrogenase
AEB_P2684	COG0672	)-iron permease
AEB_P2688	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AEB_P2691	COG5290	Psort location Cytoplasmic, score
AEB_P2692	COG2814	Major facilitator Superfamily
AEB_P2693	COG0657	acetylesterase activity
AEB_P2693	COG2755	lipolytic protein G-D-S-L family
AEB_P2695	COG0673	inositol 2-dehydrogenase activity
AEB_P2699	COG2211	Major facilitator Superfamily
AEB_P2701	COG4771	TonB-dependent receptor
AEB_P2702	COG1940	carbohydrate kinase activity
AEB_P2703	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AEB_P2717	COG4227	nucleotidyltransferase activity
AEB_P2723	COG0045	succinate-CoA ligase (ADP-forming) activity
AEB_P2727	COG5642	Protein of unknown function (DUF2384)
AEB_P2730	COG0741	lytic transglycosylase activity
AEB_P2731	COG0582	viral genome integration into host DNA
AEB_P2732	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AEB_P2733	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AEB_P2734	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AEB_P2735	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AEB_P2736	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AEB_P2737	COG0583	DNA-binding transcription factor activity
AEB_P2738	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AEB_P2741	COG0028	Belongs to the TPP enzyme family
AEB_P2744	COG3300	MHYT domain
AEB_P2744	COG5001	Diguanylate cyclase
AEB_P2745	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AEB_P2746	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEB_P2747	COG0552	protein localization to endoplasmic reticulum
AEB_P2748	COG2917	probably involved in intracellular septation
AEB_P2749	COG3158	transport of potassium into the cell
AEB_P2750	COG4235	cytochrome complex assembly
AEB_P2751	COG3088	subunit of a heme lyase
AEB_P2752	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEB_P2753	COG1138	Cytochrome C-type biogenesis protein
AEB_P2754	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AEB_P2756	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AEB_P2760	COG0254	rRNA binding
AEB_P2761	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AEB_P2764	COG0750	zinc metalloprotease
AEB_P2765	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AEB_P2766	COG0575	Belongs to the CDS family
AEB_P2767	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AEB_P2768	COG0233	cytoplasmic translational termination
AEB_P2769	COG0528	UMP kinase activity
AEB_P2770	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AEB_P2771	COG0052	Belongs to the universal ribosomal protein uS2 family
AEB_P2775	COG0688	phosphatidylethanolamine metabolic process
AEB_P2776	COG1716	ATPase activity
AEB_P2776	COG5001	Diguanylate cyclase
AEB_P2778	COG2815	serine threonine protein kinase
AEB_P2778	COG0515	serine threonine protein kinase
AEB_P2780	COG0631	protein serine/threonine phosphatase activity
AEB_P2781	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AEB_P2786	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AEB_P2789	COG1643	Atp-dependent helicase
AEB_P2790	COG0142	geranyltranstransferase activity
AEB_P2791	COG0287	Prephenate dehydrogenase
AEB_P2791	COG1605	Chorismate mutase
AEB_P2794	COG0745	RESPONSE REGULATOR receiver
AEB_P2800	COG0438	transferase activity, transferring glycosyl groups
AEB_P2801	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AEB_P2802	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AEB_P2805	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AEB_P2806	COG0511	ligase activity, forming carbon-carbon bonds
AEB_P2807	COG0439	Biotin carboxylase
AEB_P2808	COG1522	sequence-specific DNA binding
AEB_P2809	COG2205	protein histidine kinase activity
AEB_P2818	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AEB_P2819	COG0668	transmembrane transport
AEB_P2823	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AEB_P2823	COG1199	ATP-dependent helicase activity
AEB_P2826	COG0776	regulation of translation
AEB_P2827	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEB_P2828	COG0416	fatty acid biosynthetic process
AEB_P2829	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEB_P2835	COG0215	cysteine-tRNA ligase activity
AEB_P2837	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AEB_P2843	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AEB_P2844	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AEB_P2845	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AEB_P2846	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AEB_P2847	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AEB_P2855	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AEB_P2857	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AEB_P2858	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AEB_P2859	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AEB_P2863	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AEB_P2864	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AEB_P2866	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AEB_P2867	COG2133	pyrroloquinoline quinone binding
AEB_P2871	COG0617	tRNA 3'-terminal CCA addition
AEB_P2873	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AEB_P2874	COG0693	protein deglycase activity
AEB_P2875	COG0633	Ferredoxin
AEB_P2876	COG1104	cysteine desulfurase activity
AEB_P2878	COG2945	thiolester hydrolase activity
AEB_P2883	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AEB_P2884	COG0745	RESPONSE REGULATOR receiver
AEB_P2885	COG0642	Histidine kinase
AEB_P2887	COG1660	Displays ATPase and GTPase activities
AEB_P2888	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AEB_P2888	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AEB_P2890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AEB_P2892	COG1322	Protein conserved in bacteria
AEB_P2893	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AEB_P2896	COG0242	peptide deformylase activity
AEB_P2897	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AEB_P2898	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AEB_P2900	COG0101	tRNA pseudouridine synthase activity
AEB_P2901	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AEB_P2903	COG1733	regulation of RNA biosynthetic process
AEB_P2906	COG5507	3-demethylubiquinone-9 3-methyltransferase
AEB_P2915	COG1741	Belongs to the pirin family
AEB_P2918	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AEB_P2919	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AEB_P2920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AEB_P2922	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AEB_P2923	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AEB_P2927	COG0322	excinuclease ABC activity
AEB_P2929	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AEB_P2930	COG0424	maF-like protein
AEB_P2940	COG0457	Tetratricopeptide repeat
AEB_P2940	COG3710	Transcriptional regulator
AEB_P2942	COG0583	DNA-binding transcription factor activity
AEB_P2945	COG1172	Belongs to the binding-protein-dependent transport system permease family
AEB_P2949	COG2814	Major facilitator Superfamily
AEB_P2950	COG0385	Bile acid
AEB_P2952	COG2252	PERMEase
AEB_P2953	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AEB_P2956	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AEB_P2960	COG2351	hydroxyisourate hydrolase activity
AEB_P2965	COG0402	S-adenosylhomocysteine deaminase activity
AEB_P2966	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AEB_P2969	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEB_P2970	COG0346	lactoylglutathione lyase activity
AEB_P2972	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AEB_P2973	COG0583	DNA-binding transcription factor activity
AEB_P2989	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEB_P2992	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEB_P2993	COG3047	cAMP biosynthetic process
AEB_P2994	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEB_P2998	COG2271	Major facilitator Superfamily
AEB_P2999	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AEB_P3000	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AEB_P3001	COG1733	regulation of RNA biosynthetic process
AEB_P3003	COG4206	TonB-dependent receptor
AEB_P3005	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AEB_P3006	COG0612	Peptidase, M16
AEB_P3008	COG2132	Multicopper oxidase
AEB_P3009	COG1937	Protein conserved in bacteria
AEB_P3010	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AEB_P3011	COG0047	phosphoribosylformylglycinamidine synthase activity
AEB_P3012	COG1970	mechanosensitive ion channel activity
AEB_P3019	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AEB_P3020	COG0572	uridine kinase
AEB_P3021	COG4993	Dehydrogenase
AEB_P3023	COG2010	Cytochrome c
AEB_P3033	COG4993	Dehydrogenase
AEB_P3040	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AEB_P3041	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AEB_P3042	COG2080	2 iron, 2 sulfur cluster binding
AEB_P3046	COG4566	intracellular signal transduction
AEB_P3050	COG4566	intracellular signal transduction
AEB_P3051	COG4191	Histidine kinase
AEB_P3052	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P3060	COG1132	(ABC) transporter
AEB_P3063	COG0457	Tetratricopeptide repeat
AEB_P3071	COG0457	Tetratricopeptide repeat
AEB_P3076	COG1464	Belongs to the NlpA lipoprotein family
AEB_P3078	COG1116	anion transmembrane transporter activity
AEB_P3079	COG0864	Transcriptional regulator
AEB_P3082	COG0439	Biotin carboxylase
AEB_P3087	COG4946	Tricorn protease homolog
AEB_P3087	COG0793	Belongs to the peptidase S41A family
AEB_P3088	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AEB_P3090	COG3243	poly(R)-hydroxyalkanoic acid synthase
AEB_P3095	COG5001	Diguanylate cyclase
AEB_P3096	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEB_P3098	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P3099	COG4206	TonB-dependent receptor
AEB_P3102	COG0489	protein tyrosine kinase activity
AEB_P3110	COG0438	transferase activity, transferring glycosyl groups
AEB_P3114	COG1215	transferase activity, transferring glycosyl groups
AEB_P3120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AEB_P3121	COG2311	Membrane
AEB_P3124	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AEB_P3125	COG1012	belongs to the aldehyde dehydrogenase family
AEB_P3126	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AEB_P3128	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AEB_P3129	COG1113	amino acid transport
AEB_P3132	COG0583	DNA-binding transcription factor activity
AEB_P3133	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AEB_P3135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AEB_P3136	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AEB_P3139	COG4771	TonB-dependent receptor
AEB_P3141	COG3210	domain, Protein
AEB_P3144	COG2207	Transcriptional regulator
AEB_P3145	COG0708	Exodeoxyribonuclease III
AEB_P3146	COG0688	phosphatidylethanolamine metabolic process
AEB_P3155	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AEB_P3156	COG0732	type I restriction modification DNA specificity domain
AEB_P3159	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AEB_P3165	COG4227	nucleotidyltransferase activity
AEB_P3168	COG0842	Transport permease protein
AEB_P3170	COG1506	peptidase
AEB_P3175	COG1185	polyribonucleotide nucleotidyltransferase activity
AEB_P3176	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AEB_P3177	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AEB_P3179	COG1994	Peptidase M50
AEB_P3180	COG1435	thymidine kinase activity
AEB_P3181	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AEB_P3183	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AEB_P3186	COG0779	Required for maturation of 30S ribosomal subunits
AEB_P3187	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AEB_P3189	COG1842	Phage shock protein A
AEB_P3197	COG2166	iron-sulfur cluster assembly
AEB_P3200	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AEB_P3203	COG0066	3-isopropylmalate dehydratase activity
AEB_P3205	COG0271	Belongs to the BolA IbaG family
AEB_P3206	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AEB_P3207	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AEB_P3213	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AEB_P3214	COG2755	lipolytic protein G-D-S-L family
AEB_P3215	COG4181	ATPase activity
AEB_P3217	COG0297	glycogen (starch) synthase activity
AEB_P3218	COG1695	Transcriptional regulator
AEB_P3219	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AEB_P3221	COG1959	2 iron, 2 sulfur cluster binding
AEB_P3224	COG0730	response to heat
AEB_P3226	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AEB_P3228	COG2897	thiosulfate sulfurtransferase activity
AEB_P3229	COG0626	cystathionine gamma-synthase activity
AEB_P3230	COG0668	transmembrane transport
AEB_P3231	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AEB_P3231	COG1648	precorrin-2 dehydrogenase activity
AEB_P3233	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AEB_P3235	COG0175	sulfate reduction
AEB_P3238	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AEB_P3239	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AEB_P3241	COG0670	Belongs to the BI1 family
AEB_P3242	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AEB_P3245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AEB_P3246	COG0849	cell division
AEB_P3247	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AEB_P3248	COG1181	Belongs to the D-alanine--D-alanine ligase family
AEB_P3249	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AEB_P3250	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AEB_P3251	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AEB_P3253	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AEB_P3254	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AEB_P3255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AEB_P3256	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AEB_P3259	COG0275	rRNA processing
AEB_P3260	COG2001	Belongs to the MraZ family
AEB_P3263	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AEB_P3265	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AEB_P3267	COG2154	pterin-4-alpha-carbinolamine dehydratase
AEB_P3268	COG4133	protoheme IX ABC transporter activity
AEB_P3269	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AEB_P3270	COG0024	Methionine aminopeptidase
AEB_P3272	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AEB_P3274	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AEB_P3276	COG0174	glutamine synthetase
AEB_P3279	COG0729	surface antigen
AEB_P3280	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AEB_P3281	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AEB_P3282	COG2084	Dehydrogenase
AEB_P3283	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AEB_P3284	COG0805	protein transport
AEB_P3285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEB_P3286	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEB_P3287	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AEB_P3288	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AEB_P3289	COG1472	Belongs to the glycosyl hydrolase 3 family
AEB_P3292	COG0018	arginyl-trna synthetase
AEB_P3294	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AEB_P3295	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AEB_P3296	COG0328	RNA-DNA hybrid ribonuclease activity
AEB_P3302	COG4964	Belongs to the GSP D family
AEB_P3307	COG1846	Transcriptional regulator
AEB_P3308	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AEB_P3310	COG4771	TonB-dependent receptor
AEB_P3315	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AEB_P3316	COG0688	phosphatidylethanolamine metabolic process
AEB_P3318	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AEB_P3321	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AEB_P3323	COG0154	amidase activity
AEB_P3324	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AEB_P3326	COG0545	Peptidyl-prolyl cis-trans isomerase
AEB_P3327	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AEB_P3328	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AEB_P3331	COG0546	phosphoglycolate phosphatase activity
AEB_P3337	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AEB_P3338	COG0525	valine-tRNA ligase activity
AEB_P3340	COG0534	Mate efflux family protein
AEB_P3341	COG0784	Response regulator, receiver
AEB_P3344	COG0730	response to heat
AEB_P3349	COG0544	peptidyl-prolyl cis-trans isomerase activity
AEB_P3351	COG0740	serine-type endopeptidase activity
AEB_P3352	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AEB_P3356	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AEB_P3357	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AEB_P3358	COG0564	pseudouridine synthase activity
AEB_P3361	COG3023	N-Acetylmuramoyl-L-alanine amidase
AEB_P3362	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AEB_P3366	COG1160	GTP binding
AEB_P3367	COG2193	ferroxidase activity
AEB_P3370	COG1192	Involved in chromosome partitioning
AEB_P3373	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AEB_P3374	COG0540	Belongs to the ATCase OTCase family
AEB_P3375	COG0616	signal peptide processing
AEB_P3377	COG4771	TonB-dependent receptor
AEB_P3379	COG0457	Tetratricopeptide repeat
AEB_P3380	COG0488	(ABC) transporter
AEB_P3383	COG1846	Transcriptional regulator
AEB_P3385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AEB_P3386	COG1917	Cupin 2, conserved barrel domain protein
AEB_P3387	COG5285	phytanoyl-CoA dioxygenase
AEB_P3388	COG0527	aspartate kinase activity
AEB_P3389	COG0477	Major facilitator Superfamily
AEB_P3390	COG0477	Major facilitator Superfamily
AEB_P3391	COG0583	DNA-binding transcription factor activity
AEB_P3393	COG3119	arylsulfatase activity
AEB_P3394	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_P3399	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AEB_P3401	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AEB_P3402	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AEB_P3407	COG4771	TonB-dependent receptor
AEB_P3410	COG1472	Belongs to the glycosyl hydrolase 3 family
AEB_P3413	COG3119	arylsulfatase activity
AEB_P3414	COG3119	arylsulfatase activity
AEB_P3415	COG3119	arylsulfatase activity
AEB_P3416	COG3119	arylsulfatase activity
AEB_P3417	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEB_P3418	COG1609	Transcriptional regulator
AEB_P3419	COG3119	arylsulfatase activity
AEB_P3424	COG0583	DNA-binding transcription factor activity
AEB_P3425	COG0667	Aldo Keto reductase
AEB_P3426	COG2814	Major facilitator Superfamily
AEB_P3432	COG1393	Belongs to the ArsC family
AEB_P3433	COG0798	PFAM Bile acid sodium symporter
AEB_P3439	COG0408	coproporphyrinogen oxidase activity
AEB_P3441	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AEB_P3444	COG0471	metal ion transport
AEB_P3446	COG0484	heat shock protein binding
AEB_P3448	COG2885	chlorophyll binding
AEB_P3449	COG0823	Involved in the tonB-independent uptake of proteins
AEB_P3453	COG0824	Thioesterase
AEB_P3455	COG0140	phosphoribosyl-ATP diphosphatase activity
AEB_P3456	COG0107	imidazoleglycerol-phosphate synthase activity
AEB_P3458	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AEB_P3459	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AEB_P3460	COG0131	Imidazoleglycerol-phosphate dehydratase
AEB_P3463	COG0194	GDP metabolic process
AEB_P3464	COG2171	N-acyltransferase activity
AEB_P3471	COG3384	dioxygenase
AEB_P3484	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AEB_P3495	COG2814	Major facilitator Superfamily
AEB_P3502	COG1376	ErfK ybiS ycfS ynhG family protein
AEB_P3503	COG0477	Major facilitator Superfamily
AEB_P3504	COG2207	Transcriptional regulator
AEB_P3505	COG4221	oxidoreductase activity
AEB_P3506	COG1846	Transcriptional regulator
AEB_P3508	COG1566	PFAM secretion protein HlyD family protein
AEB_P3509	COG2814	Major facilitator Superfamily
AEB_P3510	COG4771	TonB-dependent receptor
AEB_P3518	COG4149	molybdate abc transporter
AEB_P3519	COG0725	ABC transporter, periplasmic molybdate-binding protein
AEB_P3520	COG3920	Histidine kinase
AEB_P3525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AEB_P3527	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AEB_P3529	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AEB_P3529	COG0352	thiamine-phosphate diphosphorylase activity
AEB_P3529	COG0351	phosphomethylpyrimidine kinase
AEB_P3544	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AEB_P3546	COG1605	Chorismate mutase
AEB_P3546	COG0077	Prephenate dehydratase
AEB_P3549	COG0714	Associated with various cellular activities
AEB_P3553	COG1446	asparaginase
AEB_P3555	COG0475	glutathione-regulated potassium exporter activity
AEB_P3555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AEB_P3556	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AEB_P3561	COG2989	Protein conserved in bacteria
AEB_P3564	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AEB_P3567	COG2255	four-way junction helicase activity
AEB_P3569	COG0632	four-way junction helicase activity
AEB_P3570	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AEB_P3571	COG0450	alkyl hydroperoxide reductase
AEB_P3572	COG3634	alkyl hydroperoxide reductase activity
AEB_P3573	COG0339	signal peptide processing
AEB_P3576	COG4395	Tim44
AEB_P3577	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AEB_P3578	COG0728	peptidoglycan biosynthetic process
AEB_P3579	COG0180	Tryptophanyl-tRNA synthetase
AEB_P3581	COG0756	dUTP diphosphatase activity
AEB_P3582	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AEB_P3584	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AEB_P3585	COG2226	methyltransferase
AEB_P3587	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AEB_P3588	COG0268	Binds directly to 16S ribosomal RNA