locus-tag	class	description
G6N82_00040	COG0596	Alpha beta hydrolase
G6N82_00060	COG5001	Diguanylate cyclase
G6N82_00065	COG5001	Diguanylate cyclase
G6N82_00065	COG3300	MHYT domain
G6N82_00070	COG0481	GTPase activity
G6N82_00095	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6N82_00100	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G6N82_00140	COG3795	YCII-related domain
G6N82_00145	COG4941	Belongs to the sigma-70 factor family
G6N82_00155	COG2264	protein methyltransferase activity
G6N82_00185	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G6N82_00220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G6N82_00225	COG3682	Transcriptional regulator
G6N82_00240	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_00255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G6N82_00255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G6N82_00265	COG1051	belongs to the nudix hydrolase family
G6N82_00275	COG0674	pyruvate-flavodoxin oxidoreductase activity
G6N82_00275	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G6N82_00290	COG0415	Belongs to the DNA photolyase family
G6N82_00305	COG4221	oxidoreductase activity
G6N82_00310	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G6N82_00320	COG1136	(ABC) transporter
G6N82_00330	COG0386	Belongs to the glutathione peroxidase family
G6N82_00345	COG0318	PFAM AMP-dependent synthetase and ligase
G6N82_00375	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N82_00380	COG0741	lytic transglycosylase activity
G6N82_00395	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G6N82_00405	COG0129	dihydroxy-acid dehydratase activity
G6N82_00410	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G6N82_00410	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G6N82_00415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G6N82_00420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6N82_00425	COG0318	PFAM AMP-dependent synthetase and ligase
G6N82_00440	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G6N82_00480	COG1530	ribonuclease E activity
G6N82_00490	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G6N82_00495	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G6N82_00510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G6N82_00520	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G6N82_00555	COG0183	Belongs to the thiolase family
G6N82_00560	COG1012	belongs to the aldehyde dehydrogenase family
G6N82_00565	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N82_00570	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N82_00575	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N82_00580	COG0649	NAD binding
G6N82_00585	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
G6N82_00595	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6N82_00600	COG1034	ATP synthesis coupled electron transport
G6N82_00605	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G6N82_00610	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N82_00620	COG0713	ATP synthesis coupled electron transport
G6N82_00635	COG1007	ATP synthesis coupled electron transport
G6N82_00645	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G6N82_00680	COG2205	protein histidine kinase activity
G6N82_00680	COG0784	Response regulator, receiver
G6N82_00680	COG2198	Histidine kinase
G6N82_00690	COG0372	Belongs to the citrate synthase family
G6N82_00695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6N82_00700	COG2333	competence protein COMEC
G6N82_00700	COG0658	competence protein
G6N82_00710	COG0303	'Molybdopterin
G6N82_00715	COG0315	cyclic pyranopterin monophosphate synthase activity
G6N82_00720	COG0134	indole-3-glycerol-phosphate synthase activity
G6N82_00725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G6N82_00735	COG3698	Phosphodiester glycosidase
G6N82_00740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6N82_00755	COG0149	triose-phosphate isomerase activity
G6N82_00765	COG0504	CTP synthase activity
G6N82_00770	COG0071	Belongs to the small heat shock protein (HSP20) family
G6N82_00780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6N82_00795	COG0596	Alpha beta hydrolase
G6N82_00800	COG1196	nuclear chromosome segregation
G6N82_00800	COG3264	Mechanosensitive ion channel
G6N82_00815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6N82_00820	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N82_00820	COG0022	dehydrogenase e1 component
G6N82_00850	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
G6N82_00860	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G6N82_00890	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G6N82_00895	COG2867	negative regulation of translational initiation
G6N82_00900	COG1546	Belongs to the CinA family
G6N82_00900	COG1058	Belongs to the CinA family
G6N82_00905	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G6N82_00905	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G6N82_00910	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G6N82_00910	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G6N82_00920	COG3852	Histidine kinase
G6N82_00935	COG2204	response regulator
G6N82_00940	COG1923	regulation of RNA biosynthetic process
G6N82_00945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G6N82_00950	COG3956	TIGRFAM MazG family protein
G6N82_00960	COG0321	lipoyl(octanoyl) transferase activity
G6N82_00960	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G6N82_00965	COG0084	hydrolase, TatD family'
G6N82_00975	COG0470	DNA polymerase III
G6N82_00980	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G6N82_00985	COG1686	Belongs to the peptidase S11 family
G6N82_00990	COG2951	lytic endotransglycosylase activity
G6N82_01000	COG1404	Belongs to the peptidase S8 family
G6N82_01005	COG3300	MHYT domain
G6N82_01005	COG5001	Diguanylate cyclase
G6N82_01015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6N82_01020	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N82_01030	COG0557	exoribonuclease II activity
G6N82_01035	COG0442	prolyl-tRNA aminoacylation
G6N82_01045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G6N82_01050	COG0477	Major facilitator Superfamily
G6N82_01070	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6N82_01080	COG0443	Heat shock 70 kDa protein
G6N82_01100	COG0456	acetyltransferase
G6N82_01115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G6N82_01120	COG1420	regulation of RNA biosynthetic process
G6N82_01125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G6N82_01130	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G6N82_01145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G6N82_01150	COG4974	Belongs to the 'phage' integrase family
G6N82_01165	COG4566	intracellular signal transduction
G6N82_01230	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
G6N82_01240	COG1629	transport
G6N82_01240	COG4774	siderophore transport
G6N82_01295	COG0798	PFAM Bile acid sodium symporter
G6N82_01305	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G6N82_01310	COG3107	peptidoglycan biosynthetic process
G6N82_01315	COG0187	DNA topoisomerase II activity
G6N82_01325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N82_01350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G6N82_01370	COG3876	Protein conserved in bacteria
G6N82_01380	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G6N82_01415	COG1960	acyl-CoA dehydrogenase activity
G6N82_01425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G6N82_01430	COG1040	competence protein
G6N82_01440	COG0574	Belongs to the PEP-utilizing enzyme family
G6N82_01440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N82_01450	COG0752	glycyl-tRNA synthetase alpha subunit
G6N82_01475	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G6N82_01480	COG0193	aminoacyl-tRNA hydrolase activity
G6N82_01495	COG0300	oxidoreductase activity
G6N82_01500	COG0012	GTP binding
G6N82_01510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G6N82_01520	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G6N82_01545	COG0772	Belongs to the SEDS family
G6N82_01560	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G6N82_01565	COG0148	phosphopyruvate hydratase activity
G6N82_01595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G6N82_01610	COG0505	Belongs to the CarA family
G6N82_01620	COG0358	DNA primase activity
G6N82_01625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G6N82_01635	COG1192	Involved in chromosome partitioning
G6N82_01640	COG0698	ribose 5-phosphate isomerase
G6N82_01645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G6N82_01655	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G6N82_01670	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G6N82_01680	COG0343	queuine tRNA-ribosyltransferase activity
G6N82_01690	COG0842	Transport permease protein
G6N82_01695	COG1131	(ABC) transporter
G6N82_01700	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G6N82_01710	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G6N82_01720	COG1722	exodeoxyribonuclease VII activity
G6N82_01735	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6N82_01780	COG0560	Phosphoserine phosphatase
G6N82_01785	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G6N82_01790	COG0028	Belongs to the TPP enzyme family
G6N82_01800	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G6N82_01805	COG2353	YceI-like domain
G6N82_01820	COG2311	Membrane
G6N82_01825	COG3618	amidohydrolase
G6N82_01850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G6N82_01860	COG5002	protein histidine kinase activity
G6N82_01865	COG0573	inorganic phosphate transmembrane transporter activity
G6N82_01875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6N82_01880	COG0704	Plays a role in the regulation of phosphate uptake
G6N82_01885	COG0745	RESPONSE REGULATOR receiver
G6N82_01890	COG0587	DNA-directed DNA polymerase activity
G6N82_01910	COG0531	amino acid
G6N82_01915	COG0733	neurotransmitter:sodium symporter activity
G6N82_01920	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G6N82_01930	COG0385	Bile acid
G6N82_01935	COG2204	response regulator
G6N82_01970	COG0483	inositol monophosphate 1-phosphatase activity
G6N82_01975	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G6N82_01985	COG0352	thiamine-phosphate diphosphorylase activity
G6N82_02000	COG0126	phosphoglycerate kinase activity
G6N82_02005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G6N82_02030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G6N82_02040	COG1234	tRNA 3'-trailer cleavage
G6N82_02070	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G6N82_02085	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_02090	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N82_02095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6N82_02100	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G6N82_02110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G6N82_02120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G6N82_02135	COG0653	protein targeting
G6N82_02145	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G6N82_02150	COG0483	inositol monophosphate 1-phosphatase activity
G6N82_02160	COG1074	ATP-dependent DNA helicase activity
G6N82_02170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G6N82_02175	COG3178	'Phosphotransferase
G6N82_02180	COG0802	atpase or kinase
G6N82_02185	COG2205	protein histidine kinase activity
G6N82_02190	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G6N82_02195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G6N82_02195	COG0678	peroxiredoxin activity
G6N82_02225	COG0302	gtp cyclohydrolase
G6N82_02260	COG0825	malonyl-CoA metabolic process
G6N82_02265	COG4974	Belongs to the 'phage' integrase family
G6N82_02280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G6N82_02285	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G6N82_02290	COG3104	oligopeptide transport
G6N82_02295	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G6N82_02305	COG4770	biotin carboxylase activity
G6N82_02310	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N82_02310	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N82_02315	COG1024	Enoyl-CoA hydratase
G6N82_02320	COG0346	lactoylglutathione lyase activity
G6N82_02325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N82_02330	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G6N82_02335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N82_02350	COG0513	Belongs to the DEAD box helicase family
G6N82_02360	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
G6N82_02370	COG0166	Belongs to the GPI family
G6N82_02380	COG0571	ribonuclease III activity
G6N82_02385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G6N82_02390	COG3174	membrane
G6N82_02395	COG0745	RESPONSE REGULATOR receiver
G6N82_02405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G6N82_02405	COG1754	DNA topoisomerase type I activity
G6N82_02410	COG0758	DNA mediated transformation
G6N82_02410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G6N82_02415	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G6N82_02425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G6N82_02430	COG0156	8-amino-7-oxononanoate synthase activity
G6N82_02480	COG1748	Saccharopine dehydrogenase
G6N82_02500	COG0492	ferredoxin-NADP+ reductase activity
G6N82_02510	COG1523	belongs to the glycosyl hydrolase 13 family
G6N82_02515	COG0033	Phosphoglucomutase
G6N82_02520	COG0297	glycogen (starch) synthase activity
G6N82_02525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G6N82_02530	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G6N82_02535	COG0058	SHG alpha-glucan phosphorylase activity
G6N82_02560	COG2197	response regulator
G6N82_02565	COG1596	polysaccharide export
G6N82_02580	COG3206	protein involved in exopolysaccharide biosynthesis
G6N82_02580	COG0489	protein tyrosine kinase activity
G6N82_02585	COG0438	transferase activity, transferring glycosyl groups
G6N82_02630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G6N82_02665	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G6N82_02675	COG2244	polysaccharide biosynthetic process
G6N82_02695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6N82_02700	COG2273	Hydrolase Family 16
G6N82_02725	COG2015	COG2015, Alkyl sulfatase and related hydrolases
G6N82_02735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G6N82_02740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6N82_02750	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G6N82_02755	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
G6N82_02760	COG0583	DNA-binding transcription factor activity
G6N82_02770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G6N82_02785	COG0028	Belongs to the TPP enzyme family
G6N82_02795	COG3300	MHYT domain
G6N82_02795	COG5001	Diguanylate cyclase
G6N82_02800	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G6N82_02805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G6N82_02810	COG0552	protein localization to endoplasmic reticulum
G6N82_02815	COG2917	probably involved in intracellular septation
G6N82_02830	COG3158	transport of potassium into the cell
G6N82_02840	COG3088	subunit of a heme lyase
G6N82_02850	COG1138	Cytochrome C-type biogenesis protein
G6N82_02855	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
G6N82_02865	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6N82_02885	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G6N82_02890	COG0254	rRNA binding
G6N82_02900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G6N82_02915	COG0750	zinc metalloprotease
G6N82_02920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G6N82_02925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G6N82_02930	COG0233	cytoplasmic translational termination
G6N82_02935	COG0528	UMP kinase activity
G6N82_02950	COG1846	Transcriptional regulator
G6N82_02955	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G6N82_02960	COG0052	Belongs to the universal ribosomal protein uS2 family
G6N82_02975	COG0688	phosphatidylethanolamine metabolic process
G6N82_02990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6N82_03000	COG0776	regulation of translation
G6N82_03015	COG0235	Class ii aldolase
G6N82_03020	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G6N82_03025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G6N82_03055	COG1643	Atp-dependent helicase
G6N82_03065	COG0142	geranyltranstransferase activity
G6N82_03070	COG0287	Prephenate dehydrogenase
G6N82_03070	COG1605	Chorismate mutase
G6N82_03080	COG2205	protein histidine kinase activity
G6N82_03115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6N82_03120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6N82_03125	COG1862	Preprotein translocase
G6N82_03135	COG2301	Belongs to the HpcH HpaI aldolase family
G6N82_03150	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G6N82_03160	COG0439	Biotin carboxylase
G6N82_03165	COG1522	sequence-specific DNA binding
G6N82_03245	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
G6N82_03260	COG0789	Transcriptional regulator
G6N82_03270	COG1228	amidohydrolase
G6N82_03295	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6N82_03315	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G6N82_03320	COG1012	belongs to the aldehyde dehydrogenase family
G6N82_03365	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G6N82_03370	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G6N82_03385	COG0314	molybdopterin synthase activity
G6N82_03395	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G6N82_03430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6N82_03445	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
G6N82_03455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G6N82_03460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G6N82_03465	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G6N82_03470	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G6N82_03480	COG0736	holo-[acyl-carrier-protein] synthase activity
G6N82_03485	COG0681	Belongs to the peptidase S26 family
G6N82_03495	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G6N82_03555	COG1741	Belongs to the pirin family
G6N82_03565	COG0596	Alpha beta hydrolase
G6N82_03575	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G6N82_03580	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G6N82_03585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G6N82_03595	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G6N82_03600	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G6N82_03605	COG1946	Acyl-CoA thioesterase
G6N82_03615	COG0531	amino acid
G6N82_03630	COG4771	TonB-dependent receptor
G6N82_03670	COG2235	arginine
G6N82_03695	COG0513	Belongs to the DEAD box helicase family
G6N82_03700	COG0322	excinuclease ABC activity
G6N82_03710	COG2081	HI0933 family
G6N82_03720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N82_03720	COG2226	methyltransferase
G6N82_03720	COG0596	Alpha beta hydrolase
G6N82_03725	COG4206	TonB-dependent receptor
G6N82_03730	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G6N82_03735	COG0424	maF-like protein
G6N82_03765	COG0612	Peptidase, M16
G6N82_03770	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6N82_03775	COG0047	phosphoribosylformylglycinamidine synthase activity
G6N82_03780	COG5001	Diguanylate cyclase
G6N82_03795	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G6N82_03815	COG0697	spore germination
G6N82_03830	COG0385	Bile acid
G6N82_03840	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G6N82_03900	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G6N82_03910	COG2189	Belongs to the N(4) N(6)-methyltransferase family
G6N82_03925	COG2133	pyrroloquinoline quinone binding
G6N82_03945	COG0617	tRNA 3'-terminal CCA addition
G6N82_03955	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G6N82_03970	COG1104	cysteine desulfurase activity
G6N82_03980	COG2945	thiolester hydrolase activity
G6N82_04005	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G6N82_04010	COG0745	RESPONSE REGULATOR receiver
G6N82_04015	COG0642	Histidine kinase
G6N82_04020	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
G6N82_04025	COG1660	Displays ATPase and GTPase activities
G6N82_04030	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6N82_04030	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6N82_04040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6N82_04055	COG1322	Protein conserved in bacteria
G6N82_04060	COG0242	peptide deformylase activity
G6N82_04065	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G6N82_04070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G6N82_04075	COG0101	tRNA pseudouridine synthase activity
G6N82_04085	COG0252	asparaginase activity
G6N82_04110	COG0277	FAD linked oxidase domain protein
G6N82_04130	COG1506	peptidase
G6N82_04145	COG0842	Transport permease protein
G6N82_04165	COG1185	polyribonucleotide nucleotidyltransferase activity
G6N82_04170	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G6N82_04175	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G6N82_04180	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G6N82_04190	COG1994	Peptidase M50
G6N82_04200	COG1435	thymidine kinase activity
G6N82_04205	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
G6N82_04215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G6N82_04225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G6N82_04240	COG0779	Required for maturation of 30S ribosomal subunits
G6N82_04245	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G6N82_04255	COG1842	Phage shock protein A
G6N82_04295	COG2166	iron-sulfur cluster assembly
G6N82_04315	COG0824	Thioesterase
G6N82_04320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G6N82_04330	COG0066	3-isopropylmalate dehydratase activity
G6N82_04345	COG0271	Belongs to the BolA IbaG family
G6N82_04350	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G6N82_04375	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G6N82_04380	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
G6N82_04400	COG3451	type IV secretory pathway VirB4
G6N82_04405	COG3702	type iv secretory pathway
G6N82_04415	COG1196	nuclear chromosome segregation
G6N82_04415	COG0741	lytic transglycosylase activity
G6N82_04415	COG0739	heme binding
G6N82_04450	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_04460	COG1960	acyl-CoA dehydrogenase activity
G6N82_04480	COG0366	Alpha amylase catalytic
G6N82_04515	COG2308	Evidence 4 Homologs of previously reported genes of
G6N82_04525	COG1305	Transglutaminase-like
G6N82_04535	COG2855	membrane
G6N82_04560	COG0667	Aldo Keto reductase
G6N82_04570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G6N82_04575	COG0431	NADPH-dependent FMN reductase
G6N82_04580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6N82_04580	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6N82_04590	COG1522	sequence-specific DNA binding
G6N82_04595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N82_04600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N82_04620	COG0800	Aldolase
G6N82_04630	COG2186	Transcriptional regulator
G6N82_04635	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_04640	COG0129	dihydroxy-acid dehydratase activity
G6N82_04645	COG3119	arylsulfatase activity
G6N82_04650	COG3119	arylsulfatase activity
G6N82_04655	COG3119	arylsulfatase activity
G6N82_04660	COG3250	beta-galactosidase activity
G6N82_04665	COG3250	beta-galactosidase activity
G6N82_04705	COG1024	Enoyl-CoA hydratase
G6N82_04715	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_04725	COG0154	amidase activity
G6N82_04755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N82_04760	COG1960	acyl-CoA dehydrogenase activity
G6N82_04805	COG0277	FAD linked oxidase domain protein
G6N82_04820	COG0604	alcohol dehydrogenase
G6N82_04830	COG2226	methyltransferase
G6N82_04845	COG1012	belongs to the aldehyde dehydrogenase family
G6N82_04860	COG1335	isochorismatase
G6N82_04870	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G6N82_04880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N82_04885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N82_04910	COG4106	trans-aconitate 2-methyltransferase activity
G6N82_04920	COG2130	NADP-dependent
G6N82_04955	COG4206	TonB-dependent receptor
G6N82_04965	COG0277	FAD linked oxidase domain protein
G6N82_04975	COG2226	methyltransferase
G6N82_04985	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_04995	COG1012	belongs to the aldehyde dehydrogenase family
G6N82_05010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N82_05015	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G6N82_05060	COG0357	Ribosomal RNA small subunit methyltransferase G
G6N82_05070	COG0596	Alpha beta hydrolase
G6N82_05100	COG4106	trans-aconitate 2-methyltransferase activity
G6N82_05105	COG2211	Major facilitator Superfamily
G6N82_05130	COG2267	carboxylic ester hydrolase activity
G6N82_05135	COG1012	belongs to the aldehyde dehydrogenase family
G6N82_05140	COG2814	Major facilitator Superfamily
G6N82_05155	COG2226	methyltransferase
G6N82_05170	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G6N82_05180	COG1053	succinate dehydrogenase
G6N82_05180	COG3976	FMN-binding domain protein
G6N82_05185	COG1414	Transcriptional regulator
G6N82_05195	COG3799	methylaspartate ammonia-lyase activity
G6N82_05200	COG2211	Major facilitator Superfamily
G6N82_05235	COG1609	Transcriptional regulator
G6N82_05255	COG1940	carbohydrate kinase activity
G6N82_05270	COG1288	antiporter activity
G6N82_05295	COG1396	sequence-specific DNA binding
G6N82_05295	COG3800	Transcriptional regulator
G6N82_05315	COG4771	TonB-dependent receptor
G6N82_05325	COG2189	Belongs to the N(4) N(6)-methyltransferase family
G6N82_05375	COG0408	coproporphyrinogen oxidase activity
G6N82_05385	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G6N82_05390	COG0471	metal ion transport
G6N82_05430	COG2885	chlorophyll binding
G6N82_05435	COG0823	Involved in the tonB-independent uptake of proteins
G6N82_05455	COG0824	Thioesterase
G6N82_05465	COG0140	phosphoribosyl-ATP diphosphatase activity
G6N82_05470	COG0107	imidazoleglycerol-phosphate synthase activity
G6N82_05475	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G6N82_05480	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G6N82_05485	COG0131	Imidazoleglycerol-phosphate dehydratase
G6N82_05495	COG0194	GDP metabolic process
G6N82_05505	COG2199	diguanylate cyclase activity
G6N82_05505	COG2200	EAL domain
G6N82_05515	COG1960	acyl-CoA dehydrogenase activity
G6N82_05520	COG1960	acyl-CoA dehydrogenase activity
G6N82_05525	COG2211	Major facilitator Superfamily
G6N82_05530	COG1960	acyl-CoA dehydrogenase activity
G6N82_05535	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G6N82_05550	COG2171	N-acyltransferase activity
G6N82_05640	COG0251	oxidation-reduction process
G6N82_05645	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G6N82_05660	COG1063	alcohol dehydrogenase
G6N82_05675	COG2070	2-Nitropropane dioxygenase
G6N82_05680	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G6N82_05685	COG4946	Tricorn protease homolog
G6N82_05685	COG0823	Involved in the tonB-independent uptake of proteins
G6N82_05685	COG1506	peptidase
G6N82_05730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N82_05735	COG2814	Major facilitator Superfamily
G6N82_05745	COG1051	belongs to the nudix hydrolase family
G6N82_05750	COG0363	glucosamine-6-phosphate deaminase activity
G6N82_05755	COG0783	Belongs to the Dps family
G6N82_05770	COG1064	alcohol dehydrogenase
G6N82_05825	COG1024	Enoyl-CoA hydratase
G6N82_05855	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G6N82_05860	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G6N82_05865	COG0509	glycine decarboxylation via glycine cleavage system
G6N82_05870	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G6N82_05885	COG0646	methionine synthase
G6N82_05885	COG1410	methionine synthase
G6N82_05890	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G6N82_05895	COG2226	methyltransferase
G6N82_06000	COG3852	Histidine kinase
G6N82_06015	COG3300	MHYT domain
G6N82_06015	COG5001	Diguanylate cyclase
G6N82_06020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G6N82_06050	COG3485	protocatechuate 3,4-dioxygenase
G6N82_06060	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_06065	COG1902	pentaerythritol trinitrate reductase activity
G6N82_06075	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_06080	COG4771	TonB-dependent receptor
G6N82_06140	COG2124	cytochrome p450
G6N82_06150	COG4206	TonB-dependent receptor
G6N82_06180	COG0582	viral genome integration into host DNA
G6N82_06255	COG2003	Belongs to the UPF0758 family
G6N82_06275	COG0436	Aminotransferase
G6N82_06280	COG3243	poly(R)-hydroxyalkanoic acid synthase
G6N82_06290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G6N82_06335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G6N82_06345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N82_06350	COG3813	Protein conserved in bacteria
G6N82_06355	COG0351	phosphomethylpyrimidine kinase
G6N82_06370	COG0248	Ppx GppA phosphatase
G6N82_06375	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G6N82_06380	COG3474	cytochrome
G6N82_06400	COG0714	Associated with various cellular activities
G6N82_06435	COG3220	belongs to the UPF0276 family
G6N82_06455	COG1595	DNA-templated transcription, initiation
G6N82_06465	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G6N82_06470	COG1971	Probably functions as a manganese efflux pump
G6N82_06475	COG0123	including yeast histone deacetylase and acetoin utilization protein
G6N82_06495	COG2989	Protein conserved in bacteria
G6N82_06505	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G6N82_06510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G6N82_06515	COG2255	four-way junction helicase activity
G6N82_06530	COG0632	four-way junction helicase activity
G6N82_06535	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G6N82_06545	COG0484	heat shock protein binding
G6N82_06550	COG0450	alkyl hydroperoxide reductase
G6N82_06560	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G6N82_06595	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G6N82_06600	COG0728	peptidoglycan biosynthetic process
G6N82_06605	COG0180	Tryptophanyl-tRNA synthetase
G6N82_06615	COG0756	dUTP diphosphatase activity
G6N82_06620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G6N82_06640	COG2226	methyltransferase
G6N82_06645	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G6N82_06650	COG0268	Binds directly to 16S ribosomal RNA
G6N82_06655	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G6N82_06660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G6N82_06665	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G6N82_06670	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N82_06685	COG1301	dicarboxylic acid transport
G6N82_06690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N82_06705	COG0625	glutathione transferase activity
G6N82_06725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N82_06730	COG1414	Transcriptional regulator
G6N82_06740	COG0655	NAD(P)H dehydrogenase (quinone) activity
G6N82_06750	COG0596	Alpha beta hydrolase
G6N82_06790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G6N82_06855	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G6N82_06860	COG0594	ribonuclease P activity
G6N82_06865	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G6N82_06870	COG0706	membrane insertase activity
G6N82_06875	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G6N82_06895	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G6N82_06905	COG2866	Carboxypeptidase
G6N82_06920	COG5328	Belongs to the UPF0262 family
G6N82_06930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G6N82_06935	COG1758	RNA polymerase activity
G6N82_06955	COG1309	transcriptional regulator
G6N82_06965	COG1136	(ABC) transporter
G6N82_06965	COG0577	efflux transmembrane transporter activity
G6N82_06975	COG1538	Outer membrane efflux protein
G6N82_07000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N82_07020	COG1115	amino acid carrier protein
G6N82_07030	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G6N82_07035	COG4765	Protein conserved in bacteria
G6N82_07065	COG0318	PFAM AMP-dependent synthetase and ligase
G6N82_07135	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G6N82_07140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G6N82_07140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6N82_07150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N82_07175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G6N82_07180	COG2010	Cytochrome c
G6N82_07180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G6N82_07185	COG0489	protein tyrosine kinase activity
G6N82_07190	COG0330	HflC and HflK could
G6N82_07195	COG0330	HflC and HflK could
G6N82_07205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6N82_07210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N82_07235	COG2813	Specifically methylates the guanine in position
G6N82_07235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N82_07240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N82_07245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6N82_07250	COG0287	Prephenate dehydrogenase
G6N82_07270	COG2884	Cell division ATP-binding protein ftsE
G6N82_07285	COG0686	Belongs to the AlaDH PNT family
G6N82_07310	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G6N82_07315	COG1335	isochorismatase
G6N82_07340	COG1802	Transcriptional regulator
G6N82_07345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N82_07350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N82_07360	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
G6N82_07365	COG2116	formate transmembrane transporter activity
G6N82_07380	COG0717	Belongs to the dCTP deaminase family
G6N82_07390	COG3268	Saccharopine dehydrogenase
G6N82_07445	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G6N82_07470	COG1372	Participates in initiation and elongation during chromosome replication
G6N82_07470	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G6N82_07480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6N82_07495	COG3300	MHYT domain
G6N82_07495	COG5001	Diguanylate cyclase
G6N82_07515	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G6N82_07515	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G6N82_07525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6N82_07560	COG1131	(ABC) transporter
G6N82_07595	COG0519	Catalyzes the synthesis of GMP from XMP
G6N82_07595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G6N82_07610	COG0318	PFAM AMP-dependent synthetase and ligase
G6N82_07670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N82_07680	COG1960	acyl-CoA dehydrogenase activity
G6N82_07690	COG0517	IMP dehydrogenase activity
G6N82_07690	COG1125	glycine betaine transport
G6N82_07705	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G6N82_07710	COG0318	PFAM AMP-dependent synthetase and ligase
G6N82_07715	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G6N82_07720	COG4771	TonB-dependent receptor
G6N82_07735	COG1674	ftsk spoiiie
G6N82_07750	COG3746	phosphate-selective porin O and P
G6N82_07755	COG3706	GGDEF domain
G6N82_07785	COG0745	RESPONSE REGULATOR receiver
G6N82_07790	COG2205	protein histidine kinase activity
G6N82_07795	COG0433	COG0433 Predicted ATPase
G6N82_07805	COG0564	pseudouridine synthase activity
G6N82_07815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G6N82_07865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N82_07870	COG0183	Belongs to the thiolase family
G6N82_07875	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
G6N82_07885	COG3186	Phenylalanine-4-hydroxylase
G6N82_07890	COG1968	undecaprenyl-diphosphatase activity
G6N82_07900	COG1132	(ABC) transporter
G6N82_07915	COG0183	Belongs to the thiolase family
G6N82_07940	COG1024	Enoyl-CoA hydratase
G6N82_07945	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G6N82_07990	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_08015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G6N82_08035	COG0739	heme binding
G6N82_08045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G6N82_08050	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G6N82_08060	COG2957	Belongs to the agmatine deiminase family
G6N82_08065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G6N82_08095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N82_08110	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G6N82_08115	COG4152	abc transporter atp-binding protein
G6N82_08130	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N82_08145	COG0776	regulation of translation
G6N82_08150	COG2188	Transcriptional regulator
G6N82_08155	COG3104	oligopeptide transport
G6N82_08175	COG2853	Lipoprotein
G6N82_08180	COG1024	Enoyl-CoA hydratase
G6N82_08190	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G6N82_08200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N82_08215	COG0138	bifunctional purine biosynthesis protein purh
G6N82_08245	COG1473	amidohydrolase
G6N82_08315	COG0501	Belongs to the peptidase M48B family
G6N82_08320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G6N82_08320	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G6N82_08335	COG3275	phosphorelay sensor kinase activity
G6N82_08360	COG0590	tRNA wobble adenosine to inosine editing
G6N82_08365	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G6N82_08380	COG1570	exodeoxyribonuclease VII activity
G6N82_08385	COG0151	Belongs to the GarS family
G6N82_08400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N82_08420	COG0316	Belongs to the HesB IscA family
G6N82_08425	COG2151	metal-sulfur cluster biosynthetic enzyme
G6N82_08435	COG0719	Fe-S assembly protein
G6N82_08440	COG0396	ATPase activity
G6N82_08455	COG0719	Fe-S assembly protein
G6N82_08460	COG1959	2 iron, 2 sulfur cluster binding
G6N82_08475	COG0167	dihydroorotate dehydrogenase activity
G6N82_08480	COG0405	Gamma-glutamyltransferase
G6N82_08485	COG1022	Amp-dependent synthetase and ligase
G6N82_08500	COG2022	thiamine diphosphate biosynthetic process
G6N82_08510	COG1612	heme a metabolic process
G6N82_08525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G6N82_08530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G6N82_08605	COG3773	Cell wall hydrolase
G6N82_08620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6N82_08625	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G6N82_08635	COG0237	dephospho-CoA kinase activity
G6N82_08640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G6N82_08645	COG0424	maF-like protein
G6N82_08650	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G6N82_08655	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G6N82_08670	COG2200	EAL domain
G6N82_08690	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G6N82_08695	COG0445	tRNA wobble uridine modification
G6N82_08700	COG0357	Ribosomal RNA small subunit methyltransferase G
G6N82_08715	COG1956	GAF domain-containing protein
G6N82_08730	COG1960	acyl-CoA dehydrogenase activity
G6N82_08750	COG1329	Transcriptional regulator
G6N82_08755	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G6N82_08770	COG0739	heme binding
G6N82_08770	COG0741	lytic transglycosylase activity
G6N82_08770	COG1196	nuclear chromosome segregation
G6N82_08775	COG0113	porphobilinogen synthase activity
G6N82_08795	COG1872	DUF167
G6N82_08820	COG4946	Tricorn protease homolog
G6N82_08820	COG0823	Involved in the tonB-independent uptake of proteins
G6N82_08820	COG1506	peptidase
G6N82_08860	COG0318	PFAM AMP-dependent synthetase and ligase
G6N82_08870	COG0739	heme binding
G6N82_08875	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G6N82_08880	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G6N82_08885	COG0799	negative regulation of ribosome biogenesis
G6N82_08890	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G6N82_08900	COG0793	Belongs to the peptidase S41A family
G6N82_08910	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
G6N82_08950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N82_08955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G6N82_08965	COG0250	Participates in transcription elongation, termination and antitermination
G6N82_08975	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6N82_08985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N82_08990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6N82_09000	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G6N82_09005	COG0367	asparagine synthase
G6N82_09020	COG1045	serine acetyltransferase
G6N82_09070	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
G6N82_09070	COG0662	Cupin 2, conserved barrel domain protein
G6N82_09085	COG0489	protein tyrosine kinase activity
G6N82_09085	COG3206	protein involved in exopolysaccharide biosynthesis
G6N82_09105	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G6N82_09110	COG1295	ribonuclease BN
G6N82_09115	COG0484	heat shock protein binding
G6N82_09120	COG0259	pyridoxamine-phosphate oxidase activity
G6N82_09145	COG0482	sulfurtransferase activity
G6N82_09165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6N82_09175	COG2733	membrane
G6N82_09190	COG2086	electron transfer activity
G6N82_09195	COG0045	succinate-CoA ligase (ADP-forming) activity
G6N82_09200	COG1218	3'(2'),5'-bisphosphate nucleotidase
G6N82_09205	COG2885	chlorophyll binding
G6N82_09210	COG1253	flavin adenine dinucleotide binding
G6N82_09220	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G6N82_09225	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G6N82_09230	COG0196	riboflavin kinase activity
G6N82_09240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G6N82_09245	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G6N82_09250	COG0588	phosphoglycerate mutase activity
G6N82_09265	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_09270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6N82_09275	COG0022	dehydrogenase e1 component
G6N82_09320	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_09340	COG0183	Belongs to the thiolase family
G6N82_09350	COG1960	acyl-CoA dehydrogenase activity
G6N82_09370	COG2130	NADP-dependent
G6N82_09380	COG2130	NADP-dependent
G6N82_09405	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_09450	COG2130	NADP-dependent
G6N82_09485	COG2814	Major facilitator Superfamily
G6N82_09540	COG0308	aminopeptidase N
G6N82_09550	COG0723	plastoquinol--plastocyanin reductase activity
G6N82_09560	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G6N82_09560	COG2857	Cytochrome c1
G6N82_09565	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G6N82_09570	COG1218	3'(2'),5'-bisphosphate nucleotidase
G6N82_09580	COG0175	sulfate reduction
G6N82_09590	COG2197	response regulator
G6N82_09595	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G6N82_09620	COG1201	RNA secondary structure unwinding
G6N82_09665	COG1494	fructose-1,6-bisphosphatase
G6N82_09670	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G6N82_09695	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G6N82_09700	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G6N82_09710	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G6N82_09715	COG0072	phenylalanine-tRNA ligase activity
G6N82_09720	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G6N82_09740	COG0347	Belongs to the P(II) protein family
G6N82_09745	COG0004	ammonium transporteR
G6N82_09770	COG1473	amidohydrolase
G6N82_09780	COG1278	Cold shock
G6N82_09785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6N82_09790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G6N82_09795	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G6N82_09805	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G6N82_09815	COG2032	superoxide dismutase activity
G6N82_09820	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
G6N82_09820	COG2885	chlorophyll binding
G6N82_09830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6N82_09840	COG5425	PFAM Usg family protein
G6N82_09845	COG0156	8-amino-7-oxononanoate synthase activity
G6N82_09850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6N82_09900	COG0747	negative chemotaxis
G6N82_09910	COG3483	tryptophan 2,3-dioxygenase activity
G6N82_09915	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G6N82_09930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6N82_09940	COG2096	Adenosyltransferase
G6N82_09945	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N82_09960	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G6N82_09965	COG0280	phosphate acetyltransferase
G6N82_09965	COG0281	malic enzyme
G6N82_09970	COG0560	Phosphoserine phosphatase
G6N82_09970	COG3830	Belongs to the UPF0237 family
G6N82_09975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G6N82_09985	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G6N82_09990	COG1137	ATPase activity
G6N82_10000	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G6N82_10005	COG0124	histidyl-tRNA synthetase
G6N82_10010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G6N82_10015	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N82_10025	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G6N82_10030	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G6N82_10070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G6N82_10070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G6N82_10095	COG0459	protein refolding
G6N82_10100	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G6N82_10110	COG0222	ribosome binding
G6N82_10115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G6N82_10125	COG3655	Transcriptional regulator
G6N82_10135	COG0085	RNA polymerase activity
G6N82_10140	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G6N82_10150	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
G6N82_10150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6N82_10160	COG0469	pyruvate kinase activity
G6N82_10170	COG3750	Belongs to the UPF0335 family
G6N82_10175	COG0393	Putative heavy-metal-binding
G6N82_10195	COG0217	transcriptional regulatory protein
G6N82_10200	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G6N82_10205	COG1393	Belongs to the ArsC family
G6N82_10215	COG0584	glycerophosphoryl diester phosphodiesterase
G6N82_10220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6N82_10225	COG0527	aspartate kinase activity
G6N82_10240	COG3447	MASE1 domain protein
G6N82_10240	COG5002	protein histidine kinase activity
G6N82_10240	COG5001	Diguanylate cyclase
G6N82_10245	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G6N82_10250	COG2070	2-Nitropropane dioxygenase
G6N82_10285	COG0330	HflC and HflK could
G6N82_10305	COG0582	viral genome integration into host DNA
G6N82_10355	COG3586	endonuclease activity
G6N82_10360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G6N82_10370	COG2189	Belongs to the N(4) N(6)-methyltransferase family
G6N82_10415	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G6N82_10420	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
G6N82_10425	COG1012	belongs to the aldehyde dehydrogenase family
G6N82_10430	COG3002	Belongs to the UPF0753 family
G6N82_10435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G6N82_10440	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G6N82_10460	COG2132	Multicopper oxidase
G6N82_10465	COG1937	Protein conserved in bacteria
G6N82_10475	COG1058	Belongs to the CinA family
G6N82_10475	COG1546	Belongs to the CinA family
G6N82_10480	COG2072	flavoprotein involved in K transport
G6N82_10500	COG1024	Enoyl-CoA hydratase
G6N82_10505	COG0183	Belongs to the thiolase family
G6N82_10530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G6N82_10560	COG2010	Cytochrome c
G6N82_10580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6N82_10635	COG2205	protein histidine kinase activity
G6N82_10635	COG2198	Histidine kinase
G6N82_10635	COG0784	Response regulator, receiver
G6N82_10690	COG0450	alkyl hydroperoxide reductase
G6N82_10705	COG1942	4-Oxalocrotonate Tautomerase
G6N82_10715	COG2084	Dehydrogenase
G6N82_10785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N82_10815	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G6N82_10820	COG1960	acyl-CoA dehydrogenase activity
G6N82_10825	COG1960	acyl-CoA dehydrogenase activity
G6N82_10830	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_10835	COG0318	PFAM AMP-dependent synthetase and ligase
G6N82_10840	COG2124	cytochrome p450
G6N82_10845	COG0318	PFAM AMP-dependent synthetase and ligase
G6N82_10850	COG0318	PFAM AMP-dependent synthetase and ligase
G6N82_10860	COG1024	Enoyl-CoA hydratase
G6N82_10865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N82_10880	COG0251	oxidation-reduction process
G6N82_10890	COG0183	Belongs to the thiolase family
G6N82_10910	COG4221	oxidoreductase activity
G6N82_10915	COG1309	transcriptional regulator
G6N82_10980	COG0582	viral genome integration into host DNA
G6N82_11020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6N82_11020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6N82_11035	COG2983	Belongs to the UPF0260 family
G6N82_11040	COG1999	signal sequence binding
G6N82_11065	COG0629	single-stranded DNA binding
G6N82_11095	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G6N82_11100	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G6N82_11110	COG0612	Peptidase, M16
G6N82_11115	COG5265	(ABC) transporter
G6N82_11170	COG5001	Diguanylate cyclase
G6N82_11180	COG2201	protein-glutamate methylesterase activity
G6N82_11185	COG0745	RESPONSE REGULATOR receiver
G6N82_11200	COG0534	Mate efflux family protein
G6N82_11205	COG2080	2 iron, 2 sulfur cluster binding
G6N82_11210	COG4774	siderophore transport
G6N82_11235	COG0321	lipoyl(octanoyl) transferase activity
G6N82_11245	COG1902	pentaerythritol trinitrate reductase activity
G6N82_11255	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G6N82_11315	COG0037	tRNA processing
G6N82_11325	COG0800	Aldolase
G6N82_11330	COG0837	glucose binding
G6N82_11335	COG0129	dihydroxy-acid dehydratase activity
G6N82_11340	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G6N82_11345	COG1609	Transcriptional regulator
G6N82_11350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G6N82_11360	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G6N82_11365	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G6N82_11375	COG4774	siderophore transport
G6N82_11380	COG1309	transcriptional regulator
G6N82_11395	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
G6N82_11420	COG0500	methyltransferase
G6N82_11425	COG1063	alcohol dehydrogenase
G6N82_11430	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
G6N82_11435	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
G6N82_11440	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
G6N82_11480	COG0644	oxidoreductase
G6N82_11485	COG2211	Major facilitator Superfamily
G6N82_11490	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G6N82_11515	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
G6N82_11520	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
G6N82_11525	COG1429	ligase activity, forming nitrogen-metal bonds
G6N82_11530	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
G6N82_11565	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
G6N82_11575	COG0156	8-amino-7-oxononanoate synthase activity
G6N82_11585	COG0583	DNA-binding transcription factor activity
G6N82_11615	COG2086	electron transfer activity
G6N82_11630	COG4771	TonB-dependent receptor
G6N82_11725	COG2130	NADP-dependent
G6N82_11735	COG2030	dehydratase
G6N82_11740	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_11745	COG1960	acyl-CoA dehydrogenase activity
G6N82_11775	COG1960	acyl-CoA dehydrogenase activity
G6N82_11790	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G6N82_11795	COG0427	acetyl-CoA hydrolase
G6N82_11800	COG3246	L-lysine catabolic process to acetate
G6N82_11805	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N82_11805	COG1024	Enoyl-CoA hydratase
G6N82_11810	COG0656	L-ascorbic acid biosynthetic process
G6N82_11835	COG4771	TonB-dependent receptor
G6N82_11865	COG2130	NADP-dependent
G6N82_11870	COG2072	flavoprotein involved in K transport
G6N82_11875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N82_11880	COG2059	Chromate
G6N82_11885	COG0471	metal ion transport
G6N82_11885	COG3273	potassium ion transport
G6N82_11905	COG0318	PFAM AMP-dependent synthetase and ligase
G6N82_11925	COG2814	Major facilitator Superfamily
G6N82_11935	COG0616	signal peptide processing
G6N82_11945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G6N82_11990	COG1160	GTP binding
G6N82_12005	COG0544	peptidyl-prolyl cis-trans isomerase activity
G6N82_12010	COG0154	amidase activity
G6N82_12015	COG0740	serine-type endopeptidase activity
G6N82_12020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G6N82_12030	COG0457	Tetratricopeptide repeat
G6N82_12040	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
G6N82_12075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G6N82_12080	COG0564	pseudouridine synthase activity
G6N82_12095	COG3023	N-Acetylmuramoyl-L-alanine amidase
G6N82_12130	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G6N82_12135	COG1215	transferase activity, transferring glycosyl groups
G6N82_12145	COG0730	response to heat
G6N82_12165	COG0525	valine-tRNA ligase activity
G6N82_12200	COG0546	phosphoglycolate phosphatase activity
G6N82_12210	COG0564	pseudouridine synthase activity
G6N82_12215	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G6N82_12220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G6N82_12235	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G6N82_12240	COG0154	amidase activity
G6N82_12250	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G6N82_12255	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G6N82_12275	COG4977	sequence-specific DNA binding
G6N82_12290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G6N82_12300	COG4206	TonB-dependent receptor
G6N82_12305	COG0457	Tetratricopeptide repeat
G6N82_12315	COG4206	TonB-dependent receptor
G6N82_12340	COG4771	TonB-dependent receptor
G6N82_12345	COG0183	Belongs to the thiolase family
G6N82_12360	COG1278	Cold shock
G6N82_12405	COG4964	Belongs to the GSP D family
G6N82_12430	COG3422	double-strand break repair
G6N82_12435	COG0328	RNA-DNA hybrid ribonuclease activity
G6N82_12440	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G6N82_12445	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G6N82_12455	COG0018	arginyl-trna synthetase
G6N82_12465	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N82_12470	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G6N82_12475	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G6N82_12480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6N82_12485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6N82_12490	COG0805	protein transport
G6N82_12505	COG2084	Dehydrogenase
G6N82_12510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G6N82_12515	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G6N82_12535	COG1476	TRANSCRIPTIONal
G6N82_12550	COG0174	glutamine synthetase
G6N82_12555	COG0347	Belongs to the P(II) protein family
G6N82_12580	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G6N82_12585	COG0024	Methionine aminopeptidase
G6N82_12595	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6N82_12600	COG4133	protoheme IX ABC transporter activity
G6N82_12605	COG2154	pterin-4-alpha-carbinolamine dehydratase
G6N82_12635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6N82_12650	COG2001	Belongs to the MraZ family
G6N82_12655	COG0275	rRNA processing
G6N82_12680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G6N82_12685	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G6N82_12695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G6N82_12700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G6N82_12710	COG1181	Belongs to the D-alanine--D-alanine ligase family
G6N82_12715	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G6N82_12750	COG0670	Belongs to the BI1 family
G6N82_12770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G6N82_12775	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G6N82_12780	COG0702	epimerase
G6N82_12790	COG0175	sulfate reduction
G6N82_12800	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6N82_12810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N82_12810	COG1648	precorrin-2 dehydrogenase activity
G6N82_12815	COG0668	transmembrane transport
G6N82_12825	COG2897	thiosulfate sulfurtransferase activity
G6N82_12835	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G6N82_12855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G6N82_12860	COG1695	Transcriptional regulator
G6N82_12870	COG0438	transferase activity, transferring glycosyl groups
G6N82_12875	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G6N82_12880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6N82_12890	COG0251	oxidation-reduction process
G6N82_12895	COG1959	2 iron, 2 sulfur cluster binding
G6N82_12920	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G6N82_12935	COG0019	diaminopimelate decarboxylase activity
G6N82_12945	COG0165	Argininosuccinate lyase
G6N82_12950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6N82_12965	COG4206	TonB-dependent receptor
G6N82_12985	COG0531	amino acid
G6N82_13000	COG4206	TonB-dependent receptor
G6N82_13005	COG0657	acetylesterase activity
G6N82_13005	COG2755	lipolytic protein G-D-S-L family
G6N82_13010	COG1301	dicarboxylic acid transport
G6N82_13015	COG4191	Histidine kinase
G6N82_13020	COG2204	response regulator
G6N82_13025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6N82_13035	COG3878	Protein conserved in bacteria
G6N82_13040	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G6N82_13060	COG0625	glutathione transferase activity
G6N82_13065	COG1960	acyl-CoA dehydrogenase activity
G6N82_13080	COG3743	rRNA binding
G6N82_13080	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G6N82_13090	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G6N82_13095	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G6N82_13115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N82_13140	COG0556	nucleotide-excision repair
G6N82_13155	COG0596	Alpha beta hydrolase
G6N82_13155	COG2226	methyltransferase
G6N82_13155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N82_13175	COG0405	Gamma-glutamyltransferase
G6N82_13180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G6N82_13190	COG4771	TonB-dependent receptor
G6N82_13200	COG1714	RDD family
G6N82_13210	COG4181	ATPase activity
G6N82_13220	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G6N82_13250	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G6N82_13260	COG1970	mechanosensitive ion channel activity
G6N82_13275	COG3724	N-succinylarginine dihydrolase activity
G6N82_13290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G6N82_13295	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G6N82_13305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G6N82_13310	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G6N82_13315	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G6N82_13330	COG0105	UTP biosynthetic process
G6N82_13345	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G6N82_13350	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G6N82_13360	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G6N82_13365	COG1045	serine acetyltransferase
G6N82_13380	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_13390	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G6N82_13410	COG1505	serine-type exopeptidase activity
G6N82_13415	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G6N82_13420	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G6N82_13430	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G6N82_13435	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G6N82_13440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6N82_13445	COG2175	clavaminate synthase activity
G6N82_13465	COG0625	glutathione transferase activity
G6N82_13470	COG3046	protein related to deoxyribodipyrimidine photolyase
G6N82_13490	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G6N82_13505	COG0215	cysteine-tRNA ligase activity
G6N82_13510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G6N82_13535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N82_13545	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G6N82_13555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6N82_13560	COG0776	regulation of translation
G6N82_13570	COG1196	nuclear chromosome segregation
G6N82_13605	COG2816	NAD+ diphosphatase activity
G6N82_13625	COG2239	Acts as a magnesium transporter
G6N82_13640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G6N82_13655	COG1309	transcriptional regulator
G6N82_13660	COG0596	Alpha beta hydrolase
G6N82_13665	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G6N82_13670	COG1253	flavin adenine dinucleotide binding
G6N82_13675	COG0583	DNA-binding transcription factor activity
G6N82_13695	COG0456	acetyltransferase
G6N82_13700	COG1214	PFAM Peptidase M22, glycoprotease
G6N82_13705	COG0778	Nitroreductase
G6N82_13710	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G6N82_13720	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G6N82_13725	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N82_13730	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
G6N82_13740	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_13750	COG2211	Major facilitator Superfamily
G6N82_13755	COG0625	glutathione transferase activity
G6N82_13775	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G6N82_13780	COG1741	Belongs to the pirin family
G6N82_13785	COG0583	DNA-binding transcription factor activity
G6N82_13820	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G6N82_13830	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
G6N82_13850	COG0473	3-isopropylmalate dehydrogenase activity
G6N82_13855	COG0463	Glycosyl transferase, family 2
G6N82_13890	COG2967	ApaG domain
G6N82_13895	COG0583	DNA-binding transcription factor activity
G6N82_13925	COG0457	Tetratricopeptide repeat
G6N82_13970	COG4964	Belongs to the GSP D family
G6N82_13995	COG1538	Outer membrane efflux protein
G6N82_14025	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G6N82_14030	COG0049	tRNA binding
G6N82_14035	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G6N82_14040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G6N82_14045	COG0051	transcription antitermination factor activity, RNA binding
G6N82_14050	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G6N82_14055	COG0088	Forms part of the polypeptide exit tunnel
G6N82_14060	COG0089	rRNA binding
G6N82_14065	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G6N82_14070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G6N82_14075	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G6N82_14080	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G6N82_14085	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G6N82_14090	COG0255	Belongs to the universal ribosomal protein uL29 family
G6N82_14095	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G6N82_14100	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G6N82_14105	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G6N82_14110	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G6N82_14115	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G6N82_14120	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G6N82_14125	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G6N82_14130	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G6N82_14135	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G6N82_14140	COG1841	ribosomal large subunit assembly
G6N82_14145	COG0200	Binds to the 23S rRNA
G6N82_14150	COG0201	protein transport
G6N82_14155	COG0563	adenylate kinase activity
G6N82_14165	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G6N82_14170	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G6N82_14175	COG0202	RNA polymerase activity
G6N82_14180	COG0203	ribosomal protein L17
G6N82_14205	COG2860	membrane
G6N82_14215	COG0154	amidase activity
G6N82_14230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6N82_14235	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N82_14240	COG0567	Dehydrogenase, E1 component
G6N82_14245	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G6N82_14250	COG0039	L-malate dehydrogenase activity
G6N82_14255	COG5001	Diguanylate cyclase
G6N82_14275	COG1120	ATPase activity
G6N82_14290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G6N82_14340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N82_14355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G6N82_14360	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
G6N82_14370	COG0384	phenazine biosynthesis protein PhzF
G6N82_14380	COG2258	MOSC domain
G6N82_14385	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G6N82_14400	COG0741	lytic transglycosylase activity
G6N82_14405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N82_14410	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G6N82_14435	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G6N82_14440	COG4106	trans-aconitate 2-methyltransferase activity
G6N82_14445	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G6N82_14450	COG0475	glutathione-regulated potassium exporter activity
G6N82_14450	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6N82_14455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6N82_14455	COG3153	acetyltransferase
G6N82_14460	COG0538	isocitrate dehydrogenase activity
G6N82_14485	COG0277	FAD linked oxidase domain protein
G6N82_14500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6N82_14505	COG0210	DNA helicase
G6N82_14510	COG0742	ribosomal rna small subunit methyltransferase
G6N82_14515	COG1187	pseudouridine synthase activity
G6N82_14525	COG2223	nitrite transmembrane transporter activity
G6N82_14530	COG0285	dihydrofolate synthase activity
G6N82_14535	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G6N82_14540	COG0159	tryptophan synthase activity
G6N82_14550	COG0133	tryptophan synthase activity
G6N82_14555	COG0135	phosphoribosylanthranilate isomerase activity
G6N82_14565	COG0284	orotidine-5'-phosphate decarboxylase activity
G6N82_14575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G6N82_14580	COG2003	Belongs to the UPF0758 family
G6N82_14605	COG0356	it plays a direct role in the translocation of protons across the membrane
G6N82_14615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G6N82_14620	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G6N82_14630	COG0604	alcohol dehydrogenase
G6N82_14630	COG3321	synthase
G6N82_14630	COG1028	Short-chain dehydrogenase reductase Sdr
G6N82_14635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N82_14650	COG0539	negative regulation of cytoplasmic translation
G6N82_14655	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G6N82_14665	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G6N82_14680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G6N82_14685	COG0228	four-way junction DNA binding
G6N82_14690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G6N82_14700	COG0336	Belongs to the RNA methyltransferase TrmD family
G6N82_14705	COG0335	large ribosomal subunit rRNA binding
G6N82_14720	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G6N82_14730	COG2814	Major facilitator Superfamily
G6N82_14735	COG1566	PFAM secretion protein HlyD family protein
G6N82_14740	COG1846	Transcriptional regulator
G6N82_14775	COG0189	ligase activity
G6N82_14775	COG4067	protein conserved in archaea
G6N82_14780	COG0189	ligase activity
G6N82_14790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G6N82_14800	COG0359	binds to the 23S rRNA
G6N82_14805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G6N82_14810	COG0360	Binds together with S18 to 16S ribosomal RNA
G6N82_14825	COG0318	PFAM AMP-dependent synthetase and ligase