locus-tag	class	description
LBX01_00025	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LBX01_00030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LBX01_00040	COG1301	dicarboxylic acid transport
LBX01_00045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LBX01_00080	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LBX01_00085	COG0706	membrane insertase activity
LBX01_00090	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LBX01_00095	COG0594	ribonuclease P activity
LBX01_00100	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LBX01_00130	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LBX01_00145	COG2866	Carboxypeptidase
LBX01_00150	COG1619	proteins homologs of microcin C7 resistance protein MccF
LBX01_00155	COG0295	cytidine deaminase activity
LBX01_00165	COG5328	Belongs to the UPF0262 family
LBX01_00170	COG0305	Participates in initiation and elongation during chromosome replication
LBX01_00175	COG0717	Belongs to the dCTP deaminase family
LBX01_00180	COG4771	TonB-dependent receptor
LBX01_00185	COG1309	transcriptional regulator
LBX01_00205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LBX01_00255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LBX01_00260	COG3047	cAMP biosynthetic process
LBX01_00270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LBX01_00305	COG1522	sequence-specific DNA binding
LBX01_00330	COG1522	sequence-specific DNA binding
LBX01_00340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LBX01_00380	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LBX01_00390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LBX01_00390	COG1199	ATP-dependent helicase activity
LBX01_00400	COG0789	Transcriptional regulator
LBX01_00415	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LBX01_00445	COG0438	transferase activity, transferring glycosyl groups
LBX01_00450	COG2945	thiolester hydrolase activity
LBX01_00450	COG0596	Alpha beta hydrolase
LBX01_00455	COG1012	belongs to the aldehyde dehydrogenase family
LBX01_00460	COG1702	phosphate starvation-inducible protein PhoH
LBX01_00480	COG0730	response to heat
LBX01_00495	COG0450	alkyl hydroperoxide reductase
LBX01_00520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LBX01_00525	COG0446	pyridine nucleotide-disulphide oxidoreductase
LBX01_00540	COG1846	Transcriptional regulator
LBX01_00595	COG0745	RESPONSE REGULATOR receiver
LBX01_00630	COG0110	maltose O-acetyltransferase activity
LBX01_00650	COG0297	glycogen (starch) synthase activity
LBX01_00655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LBX01_00665	COG0156	8-amino-7-oxononanoate synthase activity
LBX01_00750	COG5265	(ABC) transporter
LBX01_00755	COG0659	secondary active sulfate transmembrane transporter activity
LBX01_00765	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LBX01_00770	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LBX01_00790	COG0629	single-stranded DNA binding
LBX01_00815	COG1999	signal sequence binding
LBX01_00820	COG2983	Belongs to the UPF0260 family
LBX01_00840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LBX01_00840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LBX01_00850	COG2827	Endonuclease containing a URI domain
LBX01_00855	COG1448	Aminotransferase
LBX01_00875	COG1024	Enoyl-CoA hydratase
LBX01_00910	COG1376	ErfK ybiS ycfS ynhG family protein
LBX01_00915	COG0037	tRNA processing
LBX01_00950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LBX01_00965	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LBX01_00970	COG1505	serine-type exopeptidase activity
LBX01_00985	COG1902	pentaerythritol trinitrate reductase activity
LBX01_00995	COG0321	lipoyl(octanoyl) transferase activity
LBX01_01015	COG1393	Belongs to the ArsC family
LBX01_01020	COG2080	2 iron, 2 sulfur cluster binding
LBX01_01025	COG0235	Class ii aldolase
LBX01_01030	COG0534	Mate efflux family protein
LBX01_01055	COG2072	flavoprotein involved in K transport
LBX01_01060	COG1546	Belongs to the CinA family
LBX01_01060	COG1058	Belongs to the CinA family
LBX01_01070	COG0081	regulation of translation
LBX01_01075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LBX01_01080	COG0250	Participates in transcription elongation, termination and antitermination
LBX01_01100	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LBX01_01125	COG0318	PFAM AMP-dependent synthetase and ligase
LBX01_01150	COG3384	dioxygenase
LBX01_01155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LBX01_01155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LBX01_01175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LBX01_01185	COG0489	protein tyrosine kinase activity
LBX01_01195	COG0330	HflC and HflK could
LBX01_01210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LBX01_01235	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LBX01_01250	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LBX01_01260	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LBX01_01265	COG0085	RNA polymerase activity
LBX01_01275	COG3655	Transcriptional regulator
LBX01_01280	COG2885	chlorophyll binding
LBX01_01285	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LBX01_01290	COG0222	ribosome binding
LBX01_01315	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LBX01_01320	COG0459	protein refolding
LBX01_01335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LBX01_01335	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LBX01_01340	COG3920	Histidine kinase
LBX01_01350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LBX01_01370	COG2814	Major facilitator Superfamily
LBX01_01375	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LBX01_01380	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LBX01_01390	COG2890	protein-(glutamine-N5) methyltransferase activity
LBX01_01395	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LBX01_01400	COG0124	histidyl-tRNA synthetase
LBX01_01415	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LBX01_01420	COG0668	transmembrane transport
LBX01_01425	COG0312	modulator of DNA gyrase
LBX01_01435	COG1137	ATPase activity
LBX01_01440	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LBX01_01450	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LBX01_01460	COG1802	Transcriptional regulator
LBX01_01475	COG3920	Histidine kinase
LBX01_01480	COG0784	Response regulator, receiver
LBX01_01485	COG0789	Transcriptional regulator
LBX01_01505	COG1742	UPF0060 membrane protein
LBX01_01510	COG0798	PFAM Bile acid sodium symporter
LBX01_01530	COG2771	luxR family
LBX01_01550	COG4771	TonB-dependent receptor
LBX01_01555	COG0823	Involved in the tonB-independent uptake of proteins
LBX01_01555	COG1506	peptidase
LBX01_01580	COG2948	multi-organism process
LBX01_01595	COG3846	protein secretion by the type IV secretion system
LBX01_01610	COG3451	type IV secretory pathway VirB4
LBX01_01625	COG4962	Type ii secretion system protein e
LBX01_01695	COG0741	lytic transglycosylase activity
LBX01_01730	COG0629	single-stranded DNA binding
LBX01_01770	COG2132	Multicopper oxidase
LBX01_01790	COG2264	protein methyltransferase activity
LBX01_01805	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LBX01_01805	COG0678	peroxiredoxin activity
LBX01_01840	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LBX01_01850	COG2132	Multicopper oxidase
LBX01_01865	COG0672	)-iron permease
LBX01_01880	COG1012	belongs to the aldehyde dehydrogenase family
LBX01_01925	COG1230	cation diffusion facilitator family transporter
LBX01_01945	COG0737	Belongs to the 5'-nucleotidase family
LBX01_01950	COG4232	protein-disulfide reductase activity
LBX01_01960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LBX01_01985	COG3258	Cytochrome c
LBX01_02040	COG0450	alkyl hydroperoxide reductase
LBX01_02065	COG0446	pyridine nucleotide-disulphide oxidoreductase
LBX01_02070	COG0730	response to heat
LBX01_02085	COG1294	oxidase, subunit
LBX01_02095	COG0450	alkyl hydroperoxide reductase
LBX01_02100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LBX01_02115	COG4227	nucleotidyltransferase activity
LBX01_02195	COG3550	peptidyl-serine autophosphorylation
LBX01_02205	COG2199	diguanylate cyclase activity
LBX01_02215	COG1012	belongs to the aldehyde dehydrogenase family
LBX01_02220	COG0281	malic enzyme
LBX01_02220	COG0280	phosphate acetyltransferase
LBX01_02225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LBX01_02240	COG1250	3-hydroxyacyl-CoA dehydrogenase
LBX01_02245	COG2096	Adenosyltransferase
LBX01_02255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LBX01_02265	COG3483	tryptophan 2,3-dioxygenase activity
LBX01_02275	COG4166	transmembrane transport
LBX01_02330	COG0156	8-amino-7-oxononanoate synthase activity
LBX01_02340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LBX01_02345	COG1764	response to oxidative stress
LBX01_02400	COG4695	Portal protein
LBX01_02480	COG2885	chlorophyll binding
LBX01_02480	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LBX01_02485	COG2032	superoxide dismutase activity
LBX01_02495	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LBX01_02510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LBX01_02515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LBX01_02520	COG1278	Cold shock
LBX01_02530	COG1253	flavin adenine dinucleotide binding
LBX01_02555	COG0004	ammonium transporteR
LBX01_02560	COG0347	Belongs to the P(II) protein family
LBX01_02575	COG0433	COG0433 Predicted ATPase
LBX01_02585	COG0564	pseudouridine synthase activity
LBX01_02595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LBX01_02650	COG0514	ATP-dependent DNA helicase (RecQ)
LBX01_02665	COG0183	Belongs to the thiolase family
LBX01_02670	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
LBX01_02675	COG2326	polyphosphate kinase activity
LBX01_02680	COG3186	Phenylalanine-4-hydroxylase
LBX01_02695	COG1968	undecaprenyl-diphosphatase activity
LBX01_02705	COG1132	(ABC) transporter
LBX01_02730	COG0183	Belongs to the thiolase family
LBX01_02760	COG0070	glutamate synthase
LBX01_02760	COG0069	glutamate synthase activity
LBX01_02760	COG0067	glutamate synthase
LBX01_02770	COG2197	response regulator
LBX01_02775	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LBX01_02775	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LBX01_02785	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LBX01_02795	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LBX01_02825	COG0495	leucyl-tRNA aminoacylation
LBX01_02840	COG1028	Short-chain dehydrogenase reductase Sdr
LBX01_02860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LBX01_02865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LBX01_02875	COG0739	heme binding
LBX01_02880	COG2833	Protein of unknown function (DUF455)
LBX01_02885	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LBX01_02890	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LBX01_02910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LBX01_02915	COG3540	Alkaline phosphatase
LBX01_02945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LBX01_02950	COG2902	Dehydrogenase
LBX01_02960	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LBX01_02965	COG4152	abc transporter atp-binding protein
LBX01_03000	COG0482	sulfurtransferase activity
LBX01_03030	COG0259	pyridoxamine-phosphate oxidase activity
LBX01_03035	COG0484	heat shock protein binding
LBX01_03040	COG1295	ribonuclease BN
LBX01_03045	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LBX01_03065	COG3206	protein involved in exopolysaccharide biosynthesis
LBX01_03065	COG0489	protein tyrosine kinase activity
LBX01_03075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LBX01_03080	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LBX01_03105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LBX01_03120	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LBX01_03125	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LBX01_03135	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LBX01_03145	COG0793	Belongs to the peptidase S41A family
LBX01_03150	COG4942	peptidase
LBX01_03155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LBX01_03160	COG0799	negative regulation of ribosome biogenesis
LBX01_03165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LBX01_03170	COG0667	Aldo Keto reductase
LBX01_03175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LBX01_03180	COG0739	heme binding
LBX01_03195	COG0318	PFAM AMP-dependent synthetase and ligase
LBX01_03205	COG0438	transferase activity, transferring glycosyl groups
LBX01_03245	COG1793	dna ligase
LBX01_03260	COG1872	DUF167
LBX01_03275	COG0113	porphobilinogen synthase activity
LBX01_03280	COG0739	heme binding
LBX01_03295	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LBX01_03300	COG1329	Transcriptional regulator
LBX01_03315	COG0009	L-threonylcarbamoyladenylate synthase
LBX01_03320	COG1960	acyl-CoA dehydrogenase activity
LBX01_03335	COG1956	GAF domain-containing protein
LBX01_03355	COG0357	Ribosomal RNA small subunit methyltransferase G
LBX01_03360	COG0445	tRNA wobble uridine modification
LBX01_03365	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LBX01_03395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LBX01_03400	COG1981	membrane
LBX01_03405	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LBX01_03410	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LBX01_03415	COG0424	maF-like protein
LBX01_03420	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LBX01_03425	COG0237	dephospho-CoA kinase activity
LBX01_03430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LBX01_03435	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LBX01_03465	COG0316	Belongs to the HesB IscA family
LBX01_03495	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LBX01_03500	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LBX01_03500	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LBX01_03505	COG2972	Histidine kinase
LBX01_03525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LBX01_03540	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LBX01_03545	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LBX01_03615	COG4974	Belongs to the 'phage' integrase family
LBX01_03620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LBX01_03640	COG0457	Tetratricopeptide repeat
LBX01_03640	COG0515	serine threonine protein kinase
LBX01_03675	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LBX01_03695	COG0641	radical SAM
LBX01_03715	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LBX01_03750	COG0776	regulation of translation
LBX01_03795	COG0811	peptide transport
LBX01_03830	COG4716	Myosin-crossreactive antigen
LBX01_03835	COG1309	transcriptional regulator
LBX01_03845	COG1250	3-hydroxyacyl-CoA dehydrogenase
LBX01_03845	COG1024	Enoyl-CoA hydratase
LBX01_03865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LBX01_03885	COG1742	UPF0060 membrane protein
LBX01_03895	COG1280	lysine exporter protein (LysE YggA)
LBX01_03930	COG0590	tRNA wobble adenosine to inosine editing
LBX01_03945	COG0523	cobalamin synthesis protein
LBX01_03960	COG0523	cobalamin synthesis protein
LBX01_03965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LBX01_03985	COG4106	trans-aconitate 2-methyltransferase activity
LBX01_03990	COG3634	alkyl hydroperoxide reductase activity
LBX01_04005	COG0583	DNA-binding transcription factor activity
LBX01_04020	COG2948	multi-organism process
LBX01_04035	COG3846	protein secretion by the type IV secretion system
LBX01_04050	COG3451	type IV secretory pathway VirB4
LBX01_04065	COG4962	Type ii secretion system protein e
LBX01_04105	COG0758	DNA mediated transformation
LBX01_04130	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LBX01_04135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LBX01_04170	COG0741	lytic transglycosylase activity
LBX01_04175	COG5489	Protein of unknown function (DUF736)
LBX01_04195	COG1192	Involved in chromosome partitioning
LBX01_04195	COG1192	Involved in chromosome partitioning
LBX01_04225	COG1476	TRANSCRIPTIONal
LBX01_04235	COG0629	single-stranded DNA binding
LBX01_04360	COG4957	zinc ion binding
LBX01_04365	COG0776	regulation of translation
LBX01_04415	COG0811	peptide transport
LBX01_04450	COG0583	DNA-binding transcription factor activity
LBX01_04465	COG2948	multi-organism process
LBX01_04495	COG3451	type IV secretory pathway VirB4
LBX01_04510	COG4962	Type ii secretion system protein e
LBX01_04540	COG0741	lytic transglycosylase activity
LBX01_04565	COG1192	Involved in chromosome partitioning
LBX01_04605	COG0629	single-stranded DNA binding
LBX01_04615	COG3093	addiction module antidote protein HigA
LBX01_04695	COG4227	nucleotidyltransferase activity
LBX01_04735	COG1073	alpha beta
LBX01_04760	COG0656	L-ascorbic acid biosynthetic process
LBX01_04890	COG0501	Belongs to the peptidase M48B family
LBX01_04910	COG3275	phosphorelay sensor kinase activity
LBX01_04915	COG3279	Response regulator of the LytR AlgR family
LBX01_04930	COG0590	tRNA wobble adenosine to inosine editing
LBX01_04935	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LBX01_04955	COG1570	exodeoxyribonuclease VII activity
LBX01_04960	COG0151	Belongs to the GarS family
LBX01_04965	COG2814	Major facilitator Superfamily
LBX01_04980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LBX01_04995	COG0316	Belongs to the HesB IscA family
LBX01_05000	COG0456	acetyltransferase
LBX01_05005	COG2151	metal-sulfur cluster biosynthetic enzyme
LBX01_05010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LBX01_05015	COG0719	Fe-S assembly protein
LBX01_05025	COG0396	ATPase activity
LBX01_05040	COG0719	Fe-S assembly protein
LBX01_05050	COG0167	dihydroorotate dehydrogenase activity
LBX01_05055	COG0405	Gamma-glutamyltransferase
LBX01_05065	COG3293	Transposase
LBX01_05080	COG2814	Major facilitator Superfamily
LBX01_05085	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LBX01_05090	COG3958	Transketolase
LBX01_05095	COG3959	Transketolase, thiamine diphosphate binding domain
LBX01_05105	COG1082	Xylose isomerase domain protein TIM barrel
LBX01_05110	COG1304	FMN binding
LBX01_05125	COG4948	Mandelate Racemase Muconate Lactonizing
LBX01_05130	COG0179	Fumarylacetoacetate (FAA) hydrolase
LBX01_05135	COG1028	Short-chain dehydrogenase reductase Sdr
LBX01_05145	COG3250	beta-galactosidase activity
LBX01_05155	COG2211	Major facilitator Superfamily
LBX01_05165	COG2186	Transcriptional regulator
LBX01_05185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LBX01_05195	COG1024	Enoyl-CoA hydratase
LBX01_05200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LBX01_05205	COG0572	uridine kinase
LBX01_05215	COG3250	beta-galactosidase activity
LBX01_05225	COG1028	Short-chain dehydrogenase reductase Sdr
LBX01_05245	COG1472	Belongs to the glycosyl hydrolase 3 family
LBX01_05270	COG1609	Transcriptional regulator
LBX01_05280	COG1082	Xylose isomerase domain protein TIM barrel
LBX01_05285	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LBX01_05285	COG0517	IMP dehydrogenase activity
LBX01_05290	COG2176	DNA-directed DNA polymerase activity
LBX01_05300	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LBX01_05305	COG0784	Response regulator, receiver
LBX01_05305	COG2198	Histidine kinase
LBX01_05305	COG2205	protein histidine kinase activity
LBX01_05315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LBX01_05330	COG2081	HI0933 family
LBX01_05340	COG1473	amidohydrolase
LBX01_05355	COG0138	bifunctional purine biosynthesis protein purh
LBX01_05365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LBX01_05380	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LBX01_05395	COG0488	(ABC) transporter
LBX01_05405	COG2850	peptidyl-arginine hydroxylation
LBX01_05430	COG0804	urea catabolic process
LBX01_05440	COG2188	Transcriptional regulator
LBX01_05475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LBX01_05500	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LBX01_05505	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LBX01_05510	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LBX01_05515	COG2205	protein histidine kinase activity
LBX01_05525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LBX01_05540	COG2948	multi-organism process
LBX01_05555	COG3846	protein secretion by the type IV secretion system
LBX01_05570	COG3451	type IV secretory pathway VirB4
LBX01_05585	COG4962	Type ii secretion system protein e
LBX01_05640	COG1192	Involved in chromosome partitioning
LBX01_05675	COG0629	single-stranded DNA binding
LBX01_05725	COG1475	DNA binding
LBX01_05755	COG4227	nucleotidyltransferase activity
LBX01_05760	COG3547	Transposase (IS116 IS110 IS902 family)
LBX01_05765	COG1396	sequence-specific DNA binding
LBX01_05770	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LBX01_05795	COG2733	membrane
LBX01_05825	COG2086	electron transfer activity
LBX01_05835	COG0045	succinate-CoA ligase (ADP-forming) activity
LBX01_05840	COG1218	3'(2'),5'-bisphosphate nucleotidase
LBX01_05850	COG1253	flavin adenine dinucleotide binding
LBX01_05860	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LBX01_05865	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LBX01_05875	COG0196	riboflavin kinase activity
LBX01_05890	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LBX01_05895	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LBX01_05900	COG0588	phosphoglycerate mutase activity
LBX01_05945	COG0308	aminopeptidase N
LBX01_05950	COG1496	oxidoreductase activity
LBX01_05955	COG0723	plastoquinol--plastocyanin reductase activity
LBX01_05965	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LBX01_05965	COG2857	Cytochrome c1
LBX01_05970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LBX01_05995	COG1492	cobalamin metabolic process
LBX01_06010	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LBX01_06020	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LBX01_06035	COG4206	TonB-dependent receptor
LBX01_06040	COG1797	cobyrinic acid a,c-diamide synthase activity
LBX01_06050	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LBX01_06055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LBX01_06070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LBX01_06075	COG1192	Involved in chromosome partitioning
LBX01_06095	COG1201	RNA secondary structure unwinding
LBX01_06135	COG1494	fructose-1,6-bisphosphatase
LBX01_06150	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LBX01_06155	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LBX01_06170	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LBX01_06175	COG0072	phenylalanine-tRNA ligase activity
LBX01_06180	COG4221	oxidoreductase activity
LBX01_06185	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LBX01_06190	COG2205	protein histidine kinase activity
LBX01_06265	COG2814	Major facilitator Superfamily
LBX01_06270	COG1566	PFAM secretion protein HlyD family protein
LBX01_06295	COG4206	TonB-dependent receptor
LBX01_06325	COG0384	phenazine biosynthesis protein PhzF
LBX01_06335	COG1802	Transcriptional regulator
LBX01_06340	COG1301	dicarboxylic acid transport
LBX01_06345	COG2027	D-alanyl-D-alanine carboxypeptidase
LBX01_06355	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LBX01_06360	COG4948	Mandelate Racemase Muconate Lactonizing
LBX01_06400	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LBX01_06415	COG0183	Belongs to the thiolase family
LBX01_06420	COG1024	Enoyl-CoA hydratase
LBX01_06425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LBX01_06430	COG1960	acyl-CoA dehydrogenase activity
LBX01_06440	COG2267	carboxylic ester hydrolase activity
LBX01_06445	COG1960	acyl-CoA dehydrogenase activity
LBX01_06450	COG1028	Short-chain dehydrogenase reductase Sdr
LBX01_06470	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
LBX01_06485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LBX01_06505	COG0066	3-isopropylmalate dehydratase activity
LBX01_06520	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LBX01_06530	COG0824	Thioesterase
LBX01_06545	COG0330	HflC and HflK could
LBX01_06580	COG0741	lytic transglycosylase activity
LBX01_06600	COG0681	Belongs to the peptidase S26 family
LBX01_06755	COG4569	acetaldehyde dehydrogenase (acetylating) activity
LBX01_06775	COG2267	carboxylic ester hydrolase activity
LBX01_06780	COG0318	PFAM AMP-dependent synthetase and ligase
LBX01_06785	COG4771	TonB-dependent receptor
LBX01_06845	COG1960	acyl-CoA dehydrogenase activity
LBX01_06850	COG0633	Ferredoxin
LBX01_06860	COG2188	Transcriptional regulator
LBX01_06865	COG2070	2-Nitropropane dioxygenase
LBX01_06885	COG1960	acyl-CoA dehydrogenase activity
LBX01_06890	COG1960	acyl-CoA dehydrogenase activity
LBX01_06900	COG2072	flavoprotein involved in K transport
LBX01_06910	COG4771	TonB-dependent receptor
LBX01_06915	COG1538	Outer membrane efflux protein
LBX01_06955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LBX01_06960	COG1024	Enoyl-CoA hydratase
LBX01_06965	COG4771	TonB-dependent receptor
LBX01_06970	COG0318	PFAM AMP-dependent synthetase and ligase
LBX01_06990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LBX01_06995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LBX01_07010	COG0387	Pfam Sodium calcium exchanger
LBX01_07025	COG0463	Glycosyl transferase, family 2
LBX01_07035	COG1012	belongs to the aldehyde dehydrogenase family
LBX01_07045	COG3300	MHYT domain
LBX01_07045	COG5001	Diguanylate cyclase
LBX01_07075	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LBX01_07075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LBX01_07085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LBX01_07090	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LBX01_07125	COG2942	2-epimerase
LBX01_07145	COG0793	Belongs to the peptidase S41A family
LBX01_07150	COG0439	Biotin carboxylase
LBX01_07155	COG0511	ligase activity, forming carbon-carbon bonds
LBX01_07195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LBX01_07220	COG1482	cell wall glycoprotein biosynthetic process
LBX01_07245	COG1758	RNA polymerase activity
LBX01_07255	COG2259	Doxx family
LBX01_07260	COG4771	TonB-dependent receptor
LBX01_07275	COG1741	Belongs to the pirin family
LBX01_07285	COG2353	YceI-like domain
LBX01_07290	COG1741	Belongs to the pirin family
LBX01_07295	COG0583	DNA-binding transcription factor activity
LBX01_07310	COG4771	TonB-dependent receptor
LBX01_07350	COG4771	TonB-dependent receptor
LBX01_07365	COG0443	Heat shock 70 kDa protein
LBX01_07370	COG2971	BadF BadG BcrA BcrD
LBX01_07375	COG2222	sugar isomerase
LBX01_07400	COG1349	DNA-binding transcription factor activity
LBX01_07410	COG1250	3-hydroxyacyl-CoA dehydrogenase
LBX01_07410	COG1024	Enoyl-CoA hydratase
LBX01_07420	COG0318	PFAM AMP-dependent synthetase and ligase
LBX01_07435	COG1960	acyl-CoA dehydrogenase activity
LBX01_07450	COG1960	acyl-CoA dehydrogenase activity
LBX01_07475	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LBX01_07480	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LBX01_07485	COG0181	hydroxymethylbilane synthase activity
LBX01_07500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LBX01_07520	COG0556	nucleotide-excision repair
LBX01_07535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LBX01_07535	COG0596	Alpha beta hydrolase
LBX01_07535	COG2226	methyltransferase
LBX01_07540	COG2308	Evidence 4 Homologs of previously reported genes of
LBX01_07560	COG4566	intracellular signal transduction
LBX01_07570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LBX01_07575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LBX01_07590	COG1217	gtp-binding protein TYPA
LBX01_07595	COG4771	TonB-dependent receptor
LBX01_07610	COG4181	ATPase activity
LBX01_07620	COG1381	Involved in DNA repair and RecF pathway recombination
LBX01_07625	COG0473	3-isopropylmalate dehydrogenase activity
LBX01_07630	COG1215	transferase activity, transferring glycosyl groups
LBX01_07655	COG2202	Pas domain
LBX01_07655	COG3920	Histidine kinase
LBX01_07660	COG2967	ApaG domain
LBX01_07670	COG0248	Ppx GppA phosphatase
LBX01_07675	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LBX01_07680	COG0583	DNA-binding transcription factor activity
LBX01_07690	COG1196	nuclear chromosome segregation
LBX01_07725	COG2816	NAD+ diphosphatase activity
LBX01_07735	COG0730	response to heat
LBX01_07745	COG2239	Acts as a magnesium transporter
LBX01_07760	COG0583	DNA-binding transcription factor activity
LBX01_07770	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LBX01_07780	COG3118	belongs to the thioredoxin family
LBX01_07790	COG2095	MarC family integral membrane protein
LBX01_07800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LBX01_07810	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LBX01_07845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LBX01_07845	COG1372	Participates in initiation and elongation during chromosome replication
LBX01_07875	COG0454	-acetyltransferase
LBX01_07875	COG0456	acetyltransferase
LBX01_07890	COG1131	(ABC) transporter
LBX01_07900	COG0312	modulator of DNA gyrase
LBX01_07925	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LBX01_07925	COG0519	Catalyzes the synthesis of GMP from XMP
LBX01_07935	COG0318	PFAM AMP-dependent synthetase and ligase
LBX01_07945	COG1760	l-serine dehydratase
LBX01_07975	COG0204	Acyl-transferase
LBX01_07980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LBX01_07985	COG1960	acyl-CoA dehydrogenase activity
LBX01_07990	COG5001	Diguanylate cyclase
LBX01_08000	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LBX01_08005	COG0318	PFAM AMP-dependent synthetase and ligase
LBX01_08010	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LBX01_08015	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LBX01_08040	COG3746	phosphate-selective porin O and P
LBX01_08045	COG0686	Belongs to the AlaDH PNT family
LBX01_08065	COG2884	Cell division ATP-binding protein ftsE
LBX01_08085	COG0287	Prephenate dehydrogenase
LBX01_08090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LBX01_08095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LBX01_08100	COG2813	Specifically methylates the guanine in position
LBX01_08100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LBX01_08105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LBX01_08105	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LBX01_08110	COG0469	pyruvate kinase activity
LBX01_08120	COG3750	Belongs to the UPF0335 family
LBX01_08125	COG0393	Putative heavy-metal-binding
LBX01_08135	COG0217	transcriptional regulatory protein
LBX01_08145	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LBX01_08155	COG1393	Belongs to the ArsC family
LBX01_08170	COG0584	glycerophosphoryl diester phosphodiesterase
LBX01_08180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LBX01_08185	COG0527	aspartate kinase activity
LBX01_08190	COG0471	metal ion transport
LBX01_08190	COG3273	potassium ion transport
LBX01_08195	COG2070	2-Nitropropane dioxygenase
LBX01_08205	COG2119	membrane
LBX01_08220	COG2166	iron-sulfur cluster assembly
LBX01_08260	COG1842	Phage shock protein A
LBX01_08270	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LBX01_08275	COG0779	Required for maturation of 30S ribosomal subunits
LBX01_08290	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LBX01_08295	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LBX01_08300	COG1435	thymidine kinase activity
LBX01_08310	COG1994	Peptidase M50
LBX01_08320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LBX01_08325	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LBX01_08330	COG1185	polyribonucleotide nucleotidyltransferase activity
LBX01_08350	COG0842	Transport permease protein
LBX01_08555	COG1294	oxidase, subunit
LBX01_08565	COG4988	ABC transporter
LBX01_08570	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LBX01_08575	COG1473	amidohydrolase
LBX01_08580	COG1301	dicarboxylic acid transport
LBX01_08585	COG0251	oxidation-reduction process
LBX01_08590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LBX01_08600	COG4206	TonB-dependent receptor
LBX01_08610	COG1473	amidohydrolase
LBX01_08635	COG4771	TonB-dependent receptor
LBX01_08640	COG1012	belongs to the aldehyde dehydrogenase family
LBX01_08645	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LBX01_08655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LBX01_08665	COG0659	secondary active sulfate transmembrane transporter activity
LBX01_08675	COG3811	Belongs to the UPF0386 family
LBX01_08685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LBX01_08705	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LBX01_08710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LBX01_08725	COG3210	domain, Protein
LBX01_08780	COG0463	Glycosyl transferase, family 2
LBX01_08800	COG0640	Transcriptional regulator
LBX01_08820	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LBX01_08825	COG0509	glycine decarboxylation via glycine cleavage system
LBX01_08830	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LBX01_08835	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LBX01_08885	COG2274	protein secretion by the type I secretion system
LBX01_08905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LBX01_08910	COG5001	Diguanylate cyclase
LBX01_08915	COG0047	phosphoribosylformylglycinamidine synthase activity
LBX01_08920	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LBX01_08925	COG0612	Peptidase, M16
LBX01_08930	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LBX01_08955	COG0424	maF-like protein
LBX01_08960	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LBX01_08970	COG1192	Involved in chromosome partitioning
LBX01_08975	COG0322	excinuclease ABC activity
LBX01_08980	COG5002	protein histidine kinase activity
LBX01_08980	COG5001	Diguanylate cyclase
LBX01_08980	COG3447	MASE1 domain protein
LBX01_08990	COG1946	Acyl-CoA thioesterase
LBX01_09005	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LBX01_09015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LBX01_09020	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LBX01_09025	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LBX01_09035	COG0596	Alpha beta hydrolase
LBX01_09040	COG0300	oxidoreductase activity
LBX01_09075	COG1733	regulation of RNA biosynthetic process
LBX01_09110	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LBX01_09115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LBX01_09120	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LBX01_09125	COG0729	surface antigen
LBX01_09155	COG0174	glutamine synthetase
LBX01_09160	COG0347	Belongs to the P(II) protein family
LBX01_09185	COG0024	Methionine aminopeptidase
LBX01_09190	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LBX01_09195	COG4133	protoheme IX ABC transporter activity
LBX01_09200	COG2154	pterin-4-alpha-carbinolamine dehydratase
LBX01_09215	COG2070	2-Nitropropane dioxygenase
LBX01_09250	COG2001	Belongs to the MraZ family
LBX01_09255	COG0275	rRNA processing
LBX01_09270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LBX01_09280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LBX01_09285	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LBX01_09295	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LBX01_09300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LBX01_09305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LBX01_09310	COG1181	Belongs to the D-alanine--D-alanine ligase family
LBX01_09315	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LBX01_09320	COG0849	cell division
LBX01_09340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LBX01_09345	COG0670	Belongs to the BI1 family
LBX01_09360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LBX01_09365	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LBX01_09375	COG0583	DNA-binding transcription factor activity
LBX01_09390	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LBX01_09395	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LBX01_09400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LBX01_09405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LBX01_09410	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LBX01_09430	COG0583	DNA-binding transcription factor activity
LBX01_09435	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LBX01_09440	COG0697	spore germination
LBX01_09465	COG0811	peptide transport
LBX01_09530	COG4227	nucleotidyltransferase activity
LBX01_09545	COG1742	UPF0060 membrane protein
LBX01_09585	COG4372	Transposase
LBX01_09590	COG3436	PFAM IS66 Orf2 family protein
LBX01_09640	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LBX01_09645	COG1959	2 iron, 2 sulfur cluster binding
LBX01_09650	COG3634	alkyl hydroperoxide reductase activity
LBX01_09675	COG1846	Transcriptional regulator
LBX01_09680	COG2807	transmembrane transport
LBX01_09685	COG2267	carboxylic ester hydrolase activity
LBX01_09705	COG5654	RES domain protein
LBX01_09725	COG4962	Type ii secretion system protein e
LBX01_09730	COG3838	Conjugal transfer protein Trbc
LBX01_09740	COG3451	type IV secretory pathway VirB4
LBX01_09755	COG2948	multi-organism process
LBX01_09770	COG3550	peptidyl-serine autophosphorylation
LBX01_09775	COG3620	sequence-specific DNA binding
LBX01_09790	COG0745	RESPONSE REGULATOR receiver
LBX01_09840	COG2365	Tyrosine phosphatase family
LBX01_09845	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LBX01_09915	COG0175	sulfate reduction
LBX01_09925	COG1218	3'(2'),5'-bisphosphate nucleotidase
LBX01_09935	COG0776	regulation of translation
LBX01_09940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LBX01_09945	COG0416	fatty acid biosynthetic process
LBX01_09950	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LBX01_09960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LBX01_09965	COG0049	tRNA binding
LBX01_09970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LBX01_09975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LBX01_09980	COG0051	transcription antitermination factor activity, RNA binding
LBX01_09985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LBX01_09990	COG0088	Forms part of the polypeptide exit tunnel
LBX01_09995	COG0089	rRNA binding
LBX01_10000	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LBX01_10005	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LBX01_10010	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LBX01_10015	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LBX01_10020	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LBX01_10025	COG0255	Belongs to the universal ribosomal protein uL29 family
LBX01_10030	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LBX01_10035	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LBX01_10040	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LBX01_10045	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LBX01_10050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LBX01_10055	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LBX01_10060	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LBX01_10065	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LBX01_10070	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LBX01_10075	COG1841	ribosomal large subunit assembly
LBX01_10080	COG0200	Binds to the 23S rRNA
LBX01_10085	COG0201	protein transport
LBX01_10090	COG0563	adenylate kinase activity
LBX01_10100	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LBX01_10105	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LBX01_10110	COG0202	RNA polymerase activity
LBX01_10115	COG0203	ribosomal protein L17
LBX01_10130	COG2860	membrane
LBX01_10145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LBX01_10150	COG0508	dehydrogenase complex catalyzes the overall conversion of
LBX01_10155	COG0567	Dehydrogenase, E1 component
LBX01_10160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LBX01_10165	COG0039	L-malate dehydrogenase activity
LBX01_10170	COG3300	MHYT domain
LBX01_10170	COG5001	Diguanylate cyclase
LBX01_10185	COG4206	TonB-dependent receptor
LBX01_10200	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LBX01_10205	COG0339	signal peptide processing
LBX01_10215	COG0028	Belongs to the TPP enzyme family
LBX01_10225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LBX01_10250	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LBX01_10275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LBX01_10290	COG0471	metal ion transport
LBX01_10300	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LBX01_10310	COG0408	coproporphyrinogen oxidase activity
LBX01_10330	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LBX01_10350	COG2207	Transcriptional regulator
LBX01_10355	COG4221	oxidoreductase activity
LBX01_10405	COG2030	dehydratase
LBX01_10410	COG0583	DNA-binding transcription factor activity
LBX01_10425	COG1024	Enoyl-CoA hydratase
LBX01_10455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LBX01_10470	COG4957	zinc ion binding
LBX01_10490	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LBX01_10495	COG0612	Peptidase, M16
LBX01_10500	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LBX01_10505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LBX01_10510	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LBX01_10520	COG1877	trehalose-phosphatase activity
LBX01_10525	COG3387	PFAM Glycoside hydrolase 15-related
LBX01_10530	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LBX01_10540	COG0492	ferredoxin-NADP+ reductase activity
LBX01_10565	COG2226	methyltransferase
LBX01_10580	COG1748	Saccharopine dehydrogenase
LBX01_10605	COG5001	Diguanylate cyclase
LBX01_10605	COG3300	MHYT domain
LBX01_10610	COG0156	8-amino-7-oxononanoate synthase activity
LBX01_10615	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LBX01_10620	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LBX01_10625	COG0758	DNA mediated transformation
LBX01_10635	COG1754	DNA topoisomerase type I activity
LBX01_10635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LBX01_10645	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LBX01_10650	COG0571	ribonuclease III activity
LBX01_10660	COG0166	Belongs to the GPI family
LBX01_10665	COG0513	Belongs to the DEAD box helicase family
LBX01_10675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LBX01_10685	COG1396	sequence-specific DNA binding
LBX01_10685	COG3800	Transcriptional regulator
LBX01_10690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LBX01_10695	COG0346	lactoylglutathione lyase activity
LBX01_10700	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LBX01_10700	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LBX01_10705	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LBX01_10715	COG4770	biotin carboxylase activity
LBX01_10720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LBX01_10735	COG3104	oligopeptide transport
LBX01_10740	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LBX01_10745	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LBX01_10755	COG4974	Belongs to the 'phage' integrase family
LBX01_10760	COG0825	malonyl-CoA metabolic process
LBX01_10795	COG0302	gtp cyclohydrolase
LBX01_10800	COG0678	peroxiredoxin activity
LBX01_10800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LBX01_10805	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LBX01_10810	COG2205	protein histidine kinase activity
LBX01_10815	COG0802	atpase or kinase
LBX01_10820	COG3178	'Phosphotransferase
LBX01_10825	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LBX01_10830	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LBX01_10835	COG1074	ATP-dependent DNA helicase activity
LBX01_10845	COG0483	inositol monophosphate 1-phosphatase activity
LBX01_10850	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LBX01_10860	COG0653	protein targeting
LBX01_10865	COG0730	response to heat
LBX01_10880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LBX01_10900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LBX01_10915	COG2264	protein methyltransferase activity
LBX01_10925	COG1028	Short-chain dehydrogenase reductase Sdr
LBX01_10935	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LBX01_10950	COG2321	neutral zinc metallopeptidase
LBX01_10955	COG1028	Short-chain dehydrogenase reductase Sdr
LBX01_10975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LBX01_10975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LBX01_10985	COG1051	belongs to the nudix hydrolase family
LBX01_10990	COG0657	acetylesterase activity
LBX01_10995	COG0674	pyruvate-flavodoxin oxidoreductase activity
LBX01_10995	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LBX01_11000	COG1013	pyruvate-flavodoxin oxidoreductase activity
LBX01_11005	COG0671	phosphoesterase, PA-phosphatase related
LBX01_11010	COG0415	Belongs to the DNA photolyase family
LBX01_11015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LBX01_11030	COG4221	oxidoreductase activity
LBX01_11035	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LBX01_11040	COG4591	ABC-type transport system involved in lipoprotein release permease component
LBX01_11045	COG1136	(ABC) transporter
LBX01_11050	COG0386	Belongs to the glutathione peroxidase family
LBX01_11060	COG0318	PFAM AMP-dependent synthetase and ligase
LBX01_11090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LBX01_11100	COG3876	Protein conserved in bacteria
LBX01_11110	COG3739	integral membrane protein
LBX01_11115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LBX01_11130	COG0187	DNA topoisomerase II activity
LBX01_11140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LBX01_11145	COG0792	nuclease activity
LBX01_11150	COG0189	ligase activity
LBX01_11155	COG0586	Pfam SNARE associated Golgi protein
LBX01_11160	COG4974	Belongs to the 'phage' integrase family
LBX01_11165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LBX01_11175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LBX01_11180	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LBX01_11185	COG1420	regulation of RNA biosynthetic process
LBX01_11190	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LBX01_11215	COG0443	Heat shock 70 kDa protein
LBX01_11220	COG0484	heat shock protein binding
LBX01_11225	COG1752	Esterase of the alpha-beta hydrolase superfamily
LBX01_11250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LBX01_11260	COG0442	prolyl-tRNA aminoacylation
LBX01_11270	COG2234	aminopeptidase activity
LBX01_11275	COG0557	exoribonuclease II activity
LBX01_11285	COG0508	dehydrogenase complex catalyzes the overall conversion of
LBX01_11300	COG2852	Protein conserved in bacteria
LBX01_11305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LBX01_11325	COG0582	viral genome integration into host DNA
LBX01_11335	COG3081	Nucleoid-associated protein
LBX01_11345	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LBX01_11365	COG0590	tRNA wobble adenosine to inosine editing
LBX01_11370	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LBX01_11375	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LBX01_11390	COG0519	Catalyzes the synthesis of GMP from XMP
LBX01_11390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LBX01_11395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LBX01_11400	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LBX01_11435	COG1280	lysine exporter protein (LysE YggA)
LBX01_11460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LBX01_11495	COG0582	viral genome integration into host DNA
LBX01_11505	COG0772	Belongs to the SEDS family
LBX01_11520	COG1792	Involved in formation and maintenance of cell shape
LBX01_11530	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LBX01_11540	COG1012	belongs to the aldehyde dehydrogenase family
LBX01_11540	COG2030	dehydratase
LBX01_11560	COG0012	GTP binding
LBX01_11570	COG2855	membrane
LBX01_11580	COG0193	aminoacyl-tRNA hydrolase activity
LBX01_11585	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LBX01_11610	COG0752	glycyl-tRNA synthetase alpha subunit
LBX01_11615	COG0751	glycine-tRNA ligase activity
LBX01_11620	COG0574	Belongs to the PEP-utilizing enzyme family
LBX01_11620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LBX01_11635	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LBX01_11645	COG1960	acyl-CoA dehydrogenase activity
LBX01_11655	COG0521	Mo-molybdopterin cofactor biosynthetic process
LBX01_11675	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LBX01_11685	COG0129	dihydroxy-acid dehydratase activity
LBX01_11695	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LBX01_11695	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LBX01_11700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LBX01_11725	COG0318	PFAM AMP-dependent synthetase and ligase
LBX01_11730	COG0019	diaminopimelate decarboxylase activity
LBX01_11755	COG3409	Peptidoglycan-binding domain 1 protein
LBX01_11755	COG3267	Type II secretory pathway component ExeA
LBX01_11760	COG0726	polysaccharide deacetylase
LBX01_11780	COG0367	asparagine synthase
LBX01_11785	COG1024	Enoyl-CoA hydratase
LBX01_11785	COG1250	3-hydroxyacyl-CoA dehydrogenase
LBX01_11790	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LBX01_11800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LBX01_11805	COG1530	ribonuclease E activity
LBX01_11815	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LBX01_11820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LBX01_11850	COG0183	Belongs to the thiolase family
LBX01_11855	COG1012	belongs to the aldehyde dehydrogenase family
LBX01_11860	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBX01_11865	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBX01_11870	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBX01_11880	COG0649	NAD binding
LBX01_11890	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LBX01_11900	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LBX01_11910	COG1034	ATP synthesis coupled electron transport
LBX01_11915	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LBX01_11920	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBX01_11930	COG0713	ATP synthesis coupled electron transport
LBX01_11945	COG1007	ATP synthesis coupled electron transport
LBX01_11955	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LBX01_11990	COG2205	protein histidine kinase activity
LBX01_11995	COG0372	Belongs to the citrate synthase family
LBX01_12000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LBX01_12005	COG2333	competence protein COMEC
LBX01_12005	COG0658	competence protein
LBX01_12010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LBX01_12020	COG0315	cyclic pyranopterin monophosphate synthase activity
LBX01_12025	COG0134	indole-3-glycerol-phosphate synthase activity
LBX01_12030	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LBX01_12050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LBX01_12055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LBX01_12060	COG0149	triose-phosphate isomerase activity
LBX01_12070	COG0504	CTP synthase activity
LBX01_12075	COG0071	Belongs to the small heat shock protein (HSP20) family
LBX01_12085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LBX01_12100	COG0668	transmembrane transport
LBX01_12115	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LBX01_12120	COG0508	dehydrogenase complex catalyzes the overall conversion of
LBX01_12120	COG0022	dehydrogenase e1 component
LBX01_12135	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LBX01_12145	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LBX01_12165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LBX01_12175	COG1546	Belongs to the CinA family
LBX01_12175	COG1058	Belongs to the CinA family
LBX01_12185	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LBX01_12185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LBX01_12195	COG3852	Histidine kinase
LBX01_12205	COG5000	phosphorelay sensor kinase activity
LBX01_12210	COG2204	response regulator
LBX01_12215	COG1923	regulation of RNA biosynthetic process
LBX01_12220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LBX01_12225	COG3956	TIGRFAM MazG family protein
LBX01_12235	COG0321	lipoyl(octanoyl) transferase activity
LBX01_12235	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LBX01_12240	COG0084	hydrolase, TatD family'
LBX01_12245	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LBX01_12250	COG0470	DNA polymerase III
LBX01_12255	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LBX01_12270	COG2951	lytic endotransglycosylase activity
LBX01_12280	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LBX01_12285	COG3590	peptidase
LBX01_12290	COG0148	phosphopyruvate hydratase activity
LBX01_12320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LBX01_12330	COG0505	Belongs to the CarA family
LBX01_12340	COG0358	DNA primase activity
LBX01_12345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LBX01_12360	COG0698	ribose 5-phosphate isomerase
LBX01_12365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LBX01_12375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LBX01_12390	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LBX01_12395	COG0343	queuine tRNA-ribosyltransferase activity
LBX01_12405	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LBX01_12415	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LBX01_12420	COG0142	geranyltranstransferase activity
LBX01_12425	COG1722	exodeoxyribonuclease VII activity
LBX01_12435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LBX01_12445	COG0560	Phosphoserine phosphatase
LBX01_12450	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LBX01_12455	COG0028	Belongs to the TPP enzyme family
LBX01_12465	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LBX01_12475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LBX01_12480	COG3618	amidohydrolase
LBX01_12505	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LBX01_12525	COG0573	inorganic phosphate transmembrane transporter activity
LBX01_12535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LBX01_12540	COG0704	Plays a role in the regulation of phosphate uptake
LBX01_12545	COG0745	RESPONSE REGULATOR receiver
LBX01_12550	COG1280	lysine exporter protein (LysE YggA)
LBX01_12560	COG0531	amino acid
LBX01_12565	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LBX01_12585	COG2204	response regulator
LBX01_12595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LBX01_12605	COG1396	sequence-specific DNA binding
LBX01_12605	COG3800	Transcriptional regulator
LBX01_12620	COG3273	potassium ion transport
LBX01_12620	COG0471	metal ion transport
LBX01_12630	COG0483	inositol monophosphate 1-phosphatase activity
LBX01_12635	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LBX01_12650	COG1297	OPT oligopeptide transporter protein
LBX01_12655	COG0352	thiamine-phosphate diphosphorylase activity
LBX01_12665	COG3588	fructose-bisphosphate aldolase
LBX01_12675	COG0126	phosphoglycerate kinase activity
LBX01_12680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LBX01_12700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LBX01_12735	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LBX01_12775	COG1309	transcriptional regulator
LBX01_12780	COG4771	TonB-dependent receptor
LBX01_12820	COG2176	DNA-directed DNA polymerase activity
LBX01_12855	COG0114	fumarate hydratase activity
LBX01_12860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LBX01_12865	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LBX01_12885	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LBX01_12890	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LBX01_12935	COG0481	GTPase activity
LBX01_12950	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LBX01_12965	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LBX01_12970	COG1619	proteins homologs of microcin C7 resistance protein MccF
LBX01_12975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LBX01_12980	COG2354	Protein conserved in bacteria
LBX01_12985	COG0360	Binds together with S18 to 16S ribosomal RNA
LBX01_12990	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LBX01_12995	COG0359	binds to the 23S rRNA
LBX01_13005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LBX01_13010	COG0189	ligase activity
LBX01_13015	COG4067	protein conserved in archaea
LBX01_13015	COG0189	ligase activity
LBX01_13035	COG1566	PFAM secretion protein HlyD family protein
LBX01_13040	COG2814	Major facilitator Superfamily
LBX01_13045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LBX01_13060	COG0335	large ribosomal subunit rRNA binding
LBX01_13065	COG0336	Belongs to the RNA methyltransferase TrmD family
LBX01_13070	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LBX01_13075	COG0228	four-way junction DNA binding
LBX01_13080	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LBX01_13095	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LBX01_13105	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LBX01_13120	COG0539	negative regulation of cytoplasmic translation
LBX01_13130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LBX01_13140	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LBX01_13150	COG0356	it plays a direct role in the translocation of protons across the membrane
LBX01_13175	COG2003	Belongs to the UPF0758 family
LBX01_13190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LBX01_13200	COG0284	orotidine-5'-phosphate decarboxylase activity
LBX01_13210	COG0135	phosphoribosylanthranilate isomerase activity
LBX01_13220	COG0133	tryptophan synthase activity
LBX01_13225	COG0159	tryptophan synthase activity
LBX01_13230	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LBX01_13235	COG0285	dihydrofolate synthase activity
LBX01_13250	COG1187	pseudouridine synthase activity
LBX01_13255	COG0742	ribosomal rna small subunit methyltransferase
LBX01_13270	COG0210	DNA helicase
LBX01_13275	COG0513	Belongs to the DEAD box helicase family
LBX01_13285	COG0277	FAD linked oxidase domain protein
LBX01_13310	COG0538	isocitrate dehydrogenase activity
LBX01_13325	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LBX01_13340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LBX01_13365	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LBX01_13370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LBX01_13375	COG0741	lytic transglycosylase activity
LBX01_13395	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LBX01_13400	COG2258	MOSC domain
LBX01_13415	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
LBX01_13420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LBX01_13425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LBX01_13430	COG0534	Mate efflux family protein
LBX01_13435	COG0137	argininosuccinate synthase activity
LBX01_13440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LBX01_13450	COG0215	cysteine-tRNA ligase activity
LBX01_13455	COG0778	Nitroreductase
LBX01_13465	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LBX01_13490	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LBX01_13505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LBX01_13505	COG2169	Transcriptional regulator
LBX01_13515	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LBX01_13520	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LBX01_13525	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LBX01_13530	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LBX01_13535	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LBX01_13555	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LBX01_13560	COG0546	phosphoglycolate phosphatase activity
LBX01_13565	COG1028	Short-chain dehydrogenase reductase Sdr
LBX01_13575	COG1045	serine acetyltransferase
LBX01_13580	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LBX01_13590	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LBX01_13595	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LBX01_13610	COG0484	heat shock protein binding
LBX01_13620	COG2885	chlorophyll binding
LBX01_13625	COG0823	Involved in the tonB-independent uptake of proteins
LBX01_13635	COG0848	biopolymer transport protein
LBX01_13645	COG0824	Thioesterase
LBX01_13655	COG0140	phosphoribosyl-ATP diphosphatase activity
LBX01_13665	COG0107	imidazoleglycerol-phosphate synthase activity
LBX01_13670	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LBX01_13675	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LBX01_13680	COG0131	Imidazoleglycerol-phosphate dehydratase
LBX01_13695	COG0194	GDP metabolic process
LBX01_13710	COG1960	acyl-CoA dehydrogenase activity
LBX01_13715	COG1960	acyl-CoA dehydrogenase activity
LBX01_13720	COG2211	Major facilitator Superfamily
LBX01_13725	COG1960	acyl-CoA dehydrogenase activity
LBX01_13730	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LBX01_13740	COG1404	Belongs to the peptidase S8 family
LBX01_13745	COG2171	N-acyltransferase activity
LBX01_13775	COG1881	PFAM PEBP family protein
LBX01_13800	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LBX01_13805	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LBX01_13815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LBX01_13820	COG0314	molybdopterin synthase activity
LBX01_13830	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LBX01_13875	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LBX01_13880	COG0109	protoheme IX farnesyltransferase activity
LBX01_13885	COG2267	carboxylic ester hydrolase activity
LBX01_13890	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LBX01_13895	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LBX01_13900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LBX01_13905	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LBX01_13910	COG0736	holo-[acyl-carrier-protein] synthase activity
LBX01_13915	COG0681	Belongs to the peptidase S26 family
LBX01_13930	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LBX01_13950	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LBX01_14010	COG3338	carbonate dehydratase activity
LBX01_14025	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LBX01_14035	COG2133	pyrroloquinoline quinone binding
LBX01_14050	COG4773	Receptor
LBX01_14060	COG0105	UTP biosynthetic process
LBX01_14070	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LBX01_14075	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LBX01_14080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LBX01_14085	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LBX01_14090	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LBX01_14105	COG3724	N-succinylarginine dihydrolase activity
LBX01_14120	COG1970	mechanosensitive ion channel activity
LBX01_14125	COG1970	mechanosensitive ion channel activity
LBX01_14135	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LBX01_14165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LBX01_14180	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LBX01_14190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LBX01_14210	COG0625	glutathione transferase activity
LBX01_14220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LBX01_14240	COG2885	chlorophyll binding
LBX01_14290	COG0617	tRNA 3'-terminal CCA addition
LBX01_14300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LBX01_14305	COG0693	protein deglycase activity
LBX01_14315	COG1104	cysteine desulfurase activity
LBX01_14320	COG1104	cysteine desulfurase activity
LBX01_14325	COG2945	thiolester hydrolase activity
LBX01_14350	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LBX01_14355	COG0745	RESPONSE REGULATOR receiver
LBX01_14360	COG2205	protein histidine kinase activity
LBX01_14365	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LBX01_14370	COG1660	Displays ATPase and GTPase activities
LBX01_14375	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LBX01_14375	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LBX01_14385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LBX01_14395	COG1322	Protein conserved in bacteria
LBX01_14400	COG0242	peptide deformylase activity
LBX01_14405	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LBX01_14410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LBX01_14415	COG0101	tRNA pseudouridine synthase activity
LBX01_14430	COG0252	asparaginase activity
LBX01_14440	COG3118	belongs to the thioredoxin family
LBX01_14445	COG0165	Argininosuccinate lyase
LBX01_14455	COG0019	diaminopimelate decarboxylase activity
LBX01_14460	COG1648	precorrin-2 dehydrogenase activity
LBX01_14460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LBX01_14475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LBX01_14480	COG0656	L-ascorbic acid biosynthetic process
LBX01_14490	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LBX01_14495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LBX01_14505	COG0438	transferase activity, transferring glycosyl groups
LBX01_14515	COG1695	Transcriptional regulator
LBX01_14520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LBX01_14560	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LBX01_14575	COG0626	cystathionine gamma-synthase activity
LBX01_14580	COG0668	transmembrane transport
LBX01_14585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LBX01_14585	COG1648	precorrin-2 dehydrogenase activity
LBX01_14595	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LBX01_14605	COG0175	sulfate reduction
LBX01_14615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LBX01_14630	COG0028	Belongs to the TPP enzyme family
LBX01_14645	COG3300	MHYT domain
LBX01_14645	COG5001	Diguanylate cyclase
LBX01_14650	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LBX01_14655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LBX01_14660	COG0552	protein localization to endoplasmic reticulum
LBX01_14665	COG2917	probably involved in intracellular septation
LBX01_14670	COG3158	transport of potassium into the cell
LBX01_14680	COG3088	subunit of a heme lyase
LBX01_14685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LBX01_14690	COG1138	Cytochrome C-type biogenesis protein
LBX01_14695	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LBX01_14705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LBX01_14730	COG0254	rRNA binding
LBX01_14735	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LBX01_14745	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LBX01_14750	COG0750	zinc metalloprotease
LBX01_14755	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LBX01_14765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LBX01_14770	COG0233	cytoplasmic translational termination
LBX01_14775	COG0528	UMP kinase activity
LBX01_14780	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LBX01_14785	COG0052	Belongs to the universal ribosomal protein uS2 family
LBX01_14805	COG0688	phosphatidylethanolamine metabolic process
LBX01_14845	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LBX01_14850	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LBX01_14870	COG1643	Atp-dependent helicase
LBX01_14875	COG1476	TRANSCRIPTIONal
LBX01_14890	COG4115	mRNA cleavage
LBX01_14895	COG2161	toxin-antitoxin pair type II binding
LBX01_14900	COG0142	geranyltranstransferase activity
LBX01_14940	COG0488	(ABC) transporter
LBX01_14960	COG0438	transferase activity, transferring glycosyl groups
LBX01_14965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LBX01_14970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LBX01_14975	COG1862	Preprotein translocase
LBX01_15025	COG0454	-acetyltransferase
LBX01_15035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LBX01_15040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LBX01_15045	COG0745	RESPONSE REGULATOR receiver
LBX01_15050	COG5002	protein histidine kinase activity
LBX01_15070	COG2022	thiamine diphosphate biosynthetic process
LBX01_15085	COG1612	heme a metabolic process
LBX01_15100	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LBX01_15110	COG4771	TonB-dependent receptor
LBX01_15135	COG4974	Belongs to the 'phage' integrase family
LBX01_15140	COG0517	IMP dehydrogenase activity
LBX01_15150	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LBX01_15190	COG1742	UPF0060 membrane protein
LBX01_15195	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LBX01_15210	COG0583	DNA-binding transcription factor activity
LBX01_15255	COG1024	Enoyl-CoA hydratase
LBX01_15280	COG0436	Aminotransferase
LBX01_15285	COG3243	poly(R)-hydroxyalkanoic acid synthase
LBX01_15295	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LBX01_15330	COG0784	Response regulator, receiver
LBX01_15335	COG3920	Histidine kinase
LBX01_15365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LBX01_15375	COG0351	phosphomethylpyrimidine kinase
LBX01_15395	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LBX01_15400	COG3474	cytochrome
LBX01_15420	COG0714	Associated with various cellular activities
LBX01_15440	COG0454	-acetyltransferase
LBX01_15445	COG2367	Beta-lactamase
LBX01_15465	COG0583	DNA-binding transcription factor activity
LBX01_15485	COG2311	Membrane
LBX01_15510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LBX01_15515	COG0540	Belongs to the ATCase OTCase family
LBX01_15520	COG0616	signal peptide processing
LBX01_15540	COG2204	response regulator
LBX01_15565	COG3047	cAMP biosynthetic process
LBX01_15570	COG3338	carbonate dehydratase activity
LBX01_15600	COG0670	Belongs to the BI1 family
LBX01_15615	COG0659	secondary active sulfate transmembrane transporter activity
LBX01_15620	COG2059	Chromate
LBX01_15630	COG0517	IMP dehydrogenase activity
LBX01_15635	COG4974	Belongs to the 'phage' integrase family
LBX01_15650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LBX01_15655	COG1742	UPF0060 membrane protein
LBX01_15665	COG1968	undecaprenyl-diphosphatase activity
LBX01_15670	COG1607	acyl-coa hydrolase
LBX01_15675	COG0598	Magnesium transport protein CorA
LBX01_15680	COG0598	Magnesium transport protein CorA
LBX01_15750	COG0741	lytic transglycosylase activity
LBX01_15775	COG4771	TonB-dependent receptor
LBX01_15780	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
LBX01_15800	COG3451	type IV secretory pathway VirB4
LBX01_15815	COG1196	nuclear chromosome segregation
LBX01_15815	COG0741	lytic transglycosylase activity
LBX01_15815	COG0739	heme binding
LBX01_15830	COG4772	TonB-dependent receptor
LBX01_15835	COG0745	RESPONSE REGULATOR receiver
LBX01_15865	COG0800	Aldolase
LBX01_15870	COG0837	glucose binding
LBX01_15875	COG0129	dihydroxy-acid dehydratase activity
LBX01_15880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LBX01_15890	COG2301	Belongs to the HpcH HpaI aldolase family
LBX01_15900	COG0418	dihydroorotase activity
LBX01_15905	COG0354	folic acid binding
LBX01_15920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LBX01_15920	COG3153	acetyltransferase
LBX01_15935	COG1278	Cold shock
LBX01_15950	COG2824	Alkylphosphonate utilization operon protein PhnA
LBX01_15965	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LBX01_16015	COG2814	Major facilitator Superfamily
LBX01_16025	COG1051	belongs to the nudix hydrolase family
LBX01_16035	COG0783	Belongs to the Dps family
LBX01_16050	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LBX01_16055	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LBX01_16085	COG1609	Transcriptional regulator
LBX01_16090	COG1472	Belongs to the glycosyl hydrolase 3 family
LBX01_16095	COG4771	TonB-dependent receptor
LBX01_16115	COG0805	protein transport
LBX01_16120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LBX01_16125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LBX01_16130	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LBX01_16135	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LBX01_16140	COG1472	Belongs to the glycosyl hydrolase 3 family
LBX01_16150	COG0018	arginyl-trna synthetase
LBX01_16160	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LBX01_16165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LBX01_16170	COG0328	RNA-DNA hybrid ribonuclease activity
LBX01_16175	COG3422	double-strand break repair
LBX01_16200	COG4964	Belongs to the GSP D family
LBX01_16230	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LBX01_16235	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LBX01_16245	COG0183	Belongs to the thiolase family
LBX01_16275	COG0612	Peptidase, M16
LBX01_16285	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LBX01_16290	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LBX01_16300	COG0154	amidase activity
LBX01_16305	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LBX01_16320	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LBX01_16325	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LBX01_16340	COG0546	phosphoglycolate phosphatase activity
LBX01_16365	COG1127	ABC transporter
LBX01_16370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LBX01_16375	COG0525	valine-tRNA ligase activity
LBX01_16385	COG0534	Mate efflux family protein
LBX01_16400	COG0730	response to heat
LBX01_16415	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LBX01_16435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LBX01_16450	COG3023	N-Acetylmuramoyl-L-alanine amidase
LBX01_16475	COG0564	pseudouridine synthase activity
LBX01_16480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LBX01_16500	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LBX01_16505	COG0740	serine-type endopeptidase activity
LBX01_16520	COG0544	peptidyl-prolyl cis-trans isomerase activity
LBX01_16545	COG1160	GTP binding
LBX01_16560	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LBX01_16575	COG2989	Protein conserved in bacteria
LBX01_16585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LBX01_16600	COG2255	four-way junction helicase activity
LBX01_16610	COG0632	four-way junction helicase activity
LBX01_16625	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LBX01_16630	COG0450	alkyl hydroperoxide reductase
LBX01_16640	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LBX01_16645	COG1054	Belongs to the UPF0176 family
LBX01_16665	COG4395	Tim44
LBX01_16670	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LBX01_16680	COG0180	Tryptophanyl-tRNA synthetase
LBX01_16695	COG0756	dUTP diphosphatase activity
LBX01_16700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LBX01_16715	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LBX01_16720	COG2226	methyltransferase
LBX01_16725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LBX01_16730	COG0268	Binds directly to 16S ribosomal RNA