locus-tag	class	description
AVL56_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AVL56_00020	COG0187	DNA topoisomerase II activity
AVL56_00045	COG2818	Glycosylase
AVL56_00055	COG3078	GTPase activator activity
AVL56_00070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVL56_00070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVL56_00075	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AVL56_00080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AVL56_00085	COG0569	domain protein
AVL56_00090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVL56_00090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVL56_00110	COG0758	DNA mediated transformation
AVL56_00125	COG0009	L-threonylcarbamoyladenylate synthase
AVL56_00130	COG0408	coproporphyrinogen oxidase activity
AVL56_00135	COG3047	cAMP biosynthetic process
AVL56_00150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AVL56_00200	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AVL56_00220	COG2234	aminopeptidase activity
AVL56_00235	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AVL56_00260	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVL56_00300	COG3642	lipopolysaccharide core region biosynthetic process
AVL56_00305	COG0859	PFAM glycosyl transferase family 9
AVL56_00325	COG0156	8-amino-7-oxononanoate synthase activity
AVL56_00335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AVL56_00340	COG0705	Rhomboid family
AVL56_00350	COG3161	chorismate lyase activity
AVL56_00355	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AVL56_00365	COG0210	DNA helicase
AVL56_00390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AVL56_00430	COG0582	viral genome integration into host DNA
AVL56_00460	COG1620	l-lactate permease
AVL56_00480	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVL56_00480	COG1902	pentaerythritol trinitrate reductase activity
AVL56_00500	COG4638	Rieske (2fe-2S)
AVL56_00510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AVL56_00510	COG1017	nitric oxide dioxygenase activity
AVL56_00515	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AVL56_00555	COG1760	l-serine dehydratase
AVL56_00560	COG0583	DNA-binding transcription factor activity
AVL56_00575	COG1012	belongs to the aldehyde dehydrogenase family
AVL56_00580	COG4948	Mandelate Racemase Muconate Lactonizing
AVL56_00590	COG1012	belongs to the aldehyde dehydrogenase family
AVL56_00595	COG4771	TonB-dependent receptor
AVL56_00600	COG0457	Tetratricopeptide repeat
AVL56_00605	COG3850	Histidine kinase
AVL56_00605	COG4999	Histidine kinase
AVL56_00605	COG2205	protein histidine kinase activity
AVL56_00605	COG3437	response regulator, receiver
AVL56_00610	COG4773	Receptor
AVL56_00615	COG0583	DNA-binding transcription factor activity
AVL56_00630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL56_00635	COG0842	Transport permease protein
AVL56_00635	COG1129	ABC transporter
AVL56_00640	COG0842	Transport permease protein
AVL56_00650	COG1960	acyl-CoA dehydrogenase activity
AVL56_00655	COG0583	DNA-binding transcription factor activity
AVL56_00670	COG3106	COG3106 Predicted ATPase
AVL56_00690	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AVL56_00705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AVL56_00720	COG4771	TonB-dependent receptor
AVL56_00725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVL56_00735	COG0778	Nitroreductase
AVL56_00735	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AVL56_00750	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AVL56_00755	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AVL56_00760	COG1309	transcriptional regulator
AVL56_00785	COG1953	Uracil, thiamine, allantoin
AVL56_00795	COG3071	HemY protein
AVL56_00800	COG2959	enzyme of heme biosynthesis
AVL56_00810	COG0181	hydroxymethylbilane synthase activity
AVL56_00815	COG0745	RESPONSE REGULATOR receiver
AVL56_00815	COG3706	GGDEF domain
AVL56_00825	COG0194	GDP metabolic process
AVL56_00835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVL56_00845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVL56_00850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AVL56_00860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVL56_00860	COG0678	peroxiredoxin activity
AVL56_00880	COG1178	ABC-type Fe3 transport system permease component
AVL56_00885	COG3842	ATPase activity
AVL56_00890	COG3300	MHYT domain
AVL56_00890	COG5001	Diguanylate cyclase
AVL56_00900	COG2081	HI0933 family
AVL56_00905	COG0668	transmembrane transport
AVL56_00930	COG3447	MASE1 domain protein
AVL56_00930	COG5001	Diguanylate cyclase
AVL56_00930	COG5002	protein histidine kinase activity
AVL56_00940	COG0583	DNA-binding transcription factor activity
AVL56_00950	COG2076	Multidrug Resistance protein
AVL56_00965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL56_00970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL56_00980	COG0427	acetyl-CoA hydrolase
AVL56_00985	COG0123	including yeast histone deacetylase and acetoin utilization protein
AVL56_00995	COG0840	transmembrane signaling receptor activity
AVL56_01005	COG3064	Membrane
AVL56_01010	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVL56_01015	COG5002	protein histidine kinase activity
AVL56_01015	COG5001	Diguanylate cyclase
AVL56_01025	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AVL56_01035	COG0514	ATP-dependent DNA helicase (RecQ)
AVL56_01040	COG2050	protein possibly involved in aromatic compounds catabolism
AVL56_01045	COG2239	Acts as a magnesium transporter
AVL56_01055	COG0745	RESPONSE REGULATOR receiver
AVL56_01055	COG3706	GGDEF domain
AVL56_01070	COG1011	Hydrolase
AVL56_01085	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AVL56_01090	COG0019	diaminopimelate decarboxylase activity
AVL56_01120	COG0163	prenyltransferase activity
AVL56_01125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVL56_01135	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AVL56_01160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AVL56_01165	COG2814	Major facilitator Superfamily
AVL56_01170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVL56_01190	COG1085	galactose-1-phosphate uridylyltransferase
AVL56_01195	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AVL56_01205	COG0629	single-stranded DNA binding
AVL56_01220	COG0745	RESPONSE REGULATOR receiver
AVL56_01230	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AVL56_01260	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVL56_01285	COG1349	DNA-binding transcription factor activity
AVL56_01325	COG3409	Peptidoglycan-binding domain 1 protein
AVL56_01325	COG3267	Type II secretory pathway component ExeA
AVL56_01335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVL56_01340	COG1459	type II secretion system
AVL56_01380	COG1077	Cell shape determining protein MreB Mrl
AVL56_01385	COG1792	Involved in formation and maintenance of cell shape
AVL56_01390	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AVL56_01400	COG1530	ribonuclease E activity
AVL56_01410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVL56_01415	COG0312	modulator of DNA gyrase
AVL56_01425	COG3028	Belongs to the UPF0307 family
AVL56_01430	COG0312	modulator of DNA gyrase
AVL56_01445	COG0745	RESPONSE REGULATOR receiver
AVL56_01450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVL56_01450	COG4191	Histidine kinase
AVL56_01455	COG0297	glycogen (starch) synthase activity
AVL56_01465	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AVL56_01475	COG1194	a g-specific adenine glycosylase
AVL56_01530	COG0745	RESPONSE REGULATOR receiver
AVL56_01535	COG2198	Histidine kinase
AVL56_01535	COG0643	Histidine kinase
AVL56_01540	COG0835	chemotaxis
AVL56_01555	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AVL56_01560	COG2201	protein-glutamate methylesterase activity
AVL56_01575	COG0501	Belongs to the peptidase M48B family
AVL56_01610	COG1609	Transcriptional regulator
AVL56_01615	COG0673	inositol 2-dehydrogenase activity
AVL56_01625	COG2211	Major facilitator Superfamily
AVL56_01680	COG1454	alcohol dehydrogenase
AVL56_01705	COG0051	transcription antitermination factor activity, RNA binding
AVL56_01720	COG0089	rRNA binding
AVL56_01730	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AVL56_01740	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AVL56_01755	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AVL56_01760	COG0438	transferase activity, transferring glycosyl groups
AVL56_01765	COG0859	PFAM glycosyl transferase family 9
AVL56_01770	COG1519	Transferase
AVL56_01795	COG0339	signal peptide processing
AVL56_01805	COG0788	formyltetrahydrofolate deformylase activity
AVL56_01815	COG1643	Atp-dependent helicase
AVL56_01820	COG2951	lytic endotransglycosylase activity
AVL56_01830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVL56_01840	COG2354	Protein conserved in bacteria
AVL56_01865	COG0004	ammonium transporteR
AVL56_01870	COG0405	Gamma-glutamyltransferase
AVL56_01875	COG2837	iron assimilation
AVL56_01890	COG0540	Belongs to the ATCase OTCase family
AVL56_01915	COG5002	protein histidine kinase activity
AVL56_01915	COG2205	protein histidine kinase activity
AVL56_01915	COG0784	Response regulator, receiver
AVL56_01940	COG1012	belongs to the aldehyde dehydrogenase family
AVL56_01950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVL56_01960	COG0512	Glutamine amidotransferase of anthranilate synthase
AVL56_01965	COG0180	Tryptophanyl-tRNA synthetase
AVL56_01970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AVL56_01990	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AVL56_02000	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AVL56_02035	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AVL56_02040	COG0281	malic enzyme
AVL56_02045	COG0625	glutathione transferase activity
AVL56_02080	COG3300	MHYT domain
AVL56_02080	COG5001	Diguanylate cyclase
AVL56_02085	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AVL56_02085	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AVL56_02095	COG0137	argininosuccinate synthase activity
AVL56_02100	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AVL56_02115	COG1803	Methylglyoxal synthase
AVL56_02125	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AVL56_02140	COG0745	RESPONSE REGULATOR receiver
AVL56_02145	COG2205	protein histidine kinase activity
AVL56_02150	COG2267	carboxylic ester hydrolase activity
AVL56_02155	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AVL56_02170	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVL56_02180	COG4942	peptidase
AVL56_02190	COG2861	carbohydrate metabolic process
AVL56_02200	COG0584	glycerophosphoryl diester phosphodiesterase
AVL56_02215	COG1162	GTPase activity
AVL56_02220	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AVL56_02240	COG0457	Tetratricopeptide repeat
AVL56_02255	COG0028	Belongs to the TPP enzyme family
AVL56_02275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVL56_02280	COG0805	protein transport
AVL56_02295	COG3706	GGDEF domain
AVL56_02305	COG0248	Ppx GppA phosphatase
AVL56_02310	COG0513	Belongs to the DEAD box helicase family
AVL56_02315	COG3118	belongs to the thioredoxin family
AVL56_02320	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AVL56_02325	COG1473	amidohydrolase
AVL56_02330	COG0784	Response regulator, receiver
AVL56_02330	COG2205	protein histidine kinase activity
AVL56_02335	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AVL56_02345	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AVL56_02360	COG0783	Belongs to the Dps family
AVL56_02365	COG2133	pyrroloquinoline quinone binding
AVL56_02375	COG3118	belongs to the thioredoxin family
AVL56_02385	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AVL56_02395	COG1012	belongs to the aldehyde dehydrogenase family
AVL56_02410	COG1757	Na H antiporter
AVL56_02435	COG3876	Protein conserved in bacteria
AVL56_02440	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AVL56_02460	COG0346	lactoylglutathione lyase activity
AVL56_02475	COG0840	transmembrane signaling receptor activity
AVL56_02535	COG4115	mRNA cleavage
AVL56_02540	COG2161	toxin-antitoxin pair type II binding
AVL56_02635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVL56_02690	COG0183	Belongs to the thiolase family
AVL56_02695	COG1024	Enoyl-CoA hydratase
AVL56_02695	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVL56_02705	COG0006	proline dipeptidase activity
AVL56_02715	COG0142	geranyltranstransferase activity
AVL56_02775	COG1238	metal cluster binding
AVL56_02785	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AVL56_02790	COG0585	pseudouridine synthase activity
AVL56_02805	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AVL56_02815	COG0840	transmembrane signaling receptor activity
AVL56_02820	COG0506	proline dehydrogenase activity
AVL56_02820	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AVL56_02820	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AVL56_02835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL56_02845	COG2770	Histidine kinase
AVL56_02845	COG2205	protein histidine kinase activity
AVL56_02850	COG4991	sh3 domain protein
AVL56_02855	COG3025	triphosphatase activity
AVL56_02870	COG0494	nUDIX hydrolase
AVL56_02875	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AVL56_02880	COG0730	response to heat
AVL56_02885	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AVL56_02890	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AVL56_02895	COG2201	protein-glutamate methylesterase activity
AVL56_02900	COG3706	GGDEF domain
AVL56_02905	COG0784	Response regulator, receiver
AVL56_02905	COG5002	protein histidine kinase activity
AVL56_02925	COG0564	pseudouridine synthase activity
AVL56_02935	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AVL56_02950	COG1802	Transcriptional regulator
AVL56_02955	COG3119	arylsulfatase activity
AVL56_02960	COG1012	belongs to the aldehyde dehydrogenase family
AVL56_02965	COG1028	Short-chain dehydrogenase reductase Sdr
AVL56_02970	COG1063	alcohol dehydrogenase
AVL56_02975	COG4948	Mandelate Racemase Muconate Lactonizing
AVL56_02980	COG2814	Major facilitator Superfamily
AVL56_03000	COG2124	cytochrome p450
AVL56_03100	COG3119	arylsulfatase activity
AVL56_03135	COG3119	arylsulfatase activity
AVL56_03150	COG1648	precorrin-2 dehydrogenase activity
AVL56_03150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AVL56_03170	COG1538	Outer membrane efflux protein
AVL56_03175	COG0494	nUDIX hydrolase
AVL56_03190	COG3150	esterase
AVL56_03205	COG4251	negative regulation of phosphorylation
AVL56_03210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVL56_03230	COG1509	lysine 2,3-aminomutase activity
AVL56_03260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AVL56_03275	COG0271	Belongs to the BolA IbaG family
AVL56_03280	COG0671	phosphoesterase, PA-phosphatase related
AVL56_03290	COG3707	response regulator
AVL56_03300	COG0659	secondary active sulfate transmembrane transporter activity
AVL56_03305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AVL56_03310	COG2146	nitrite reductase [NAD(P)H] activity
AVL56_03315	COG0243	molybdopterin cofactor binding
AVL56_03320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AVL56_03320	COG1648	precorrin-2 dehydrogenase activity
AVL56_03325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVL56_03335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVL56_03335	COG1116	anion transmembrane transporter activity
AVL56_03340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVL56_03345	COG1116	anion transmembrane transporter activity
AVL56_03360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AVL56_03365	COG4206	TonB-dependent receptor
AVL56_03370	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AVL56_03375	COG0348	domain, Protein
AVL56_03390	COG1960	acyl-CoA dehydrogenase activity
AVL56_03415	COG4948	Mandelate Racemase Muconate Lactonizing
AVL56_03435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL56_03455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVL56_03460	COG0358	DNA primase activity
AVL56_03465	COG1610	YqeY-like protein
AVL56_03485	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AVL56_03490	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AVL56_03505	COG0537	adenosine 5'-monophosphoramidase activity
AVL56_03520	COG3135	benzoate transporter
AVL56_03525	COG1396	sequence-specific DNA binding
AVL56_03530	COG2974	May be involved in recombination
AVL56_03535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVL56_03535	COG4191	Histidine kinase
AVL56_03540	COG0745	RESPONSE REGULATOR receiver
AVL56_03545	COG5002	protein histidine kinase activity
AVL56_03575	COG0811	peptide transport
AVL56_03580	COG0811	peptide transport
AVL56_03585	COG0848	biopolymer transport protein
AVL56_03590	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AVL56_03600	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AVL56_03605	COG3437	response regulator, receiver
AVL56_03615	COG0318	PFAM AMP-dependent synthetase and ligase
AVL56_03625	COG2133	pyrroloquinoline quinone binding
AVL56_03630	COG1049	propionate catabolic process, 2-methylcitrate cycle
AVL56_03650	COG0527	aspartate kinase activity
AVL56_03655	COG0840	transmembrane signaling receptor activity
AVL56_03660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AVL56_03670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AVL56_03675	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AVL56_03680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVL56_03685	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AVL56_03690	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AVL56_03700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AVL56_03720	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AVL56_03730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AVL56_03735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVL56_03740	COG3956	TIGRFAM MazG family protein
AVL56_03760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AVL56_03765	COG1595	DNA-templated transcription, initiation
AVL56_03775	COG4206	TonB-dependent receptor
AVL56_03785	COG1473	amidohydrolase
AVL56_03790	COG0723	plastoquinol--plastocyanin reductase activity
AVL56_03795	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AVL56_03800	COG2857	Cytochrome c1
AVL56_03805	COG0625	glutathione transferase activity
AVL56_03810	COG2969	positive regulation of protein catabolic process
AVL56_03815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL56_03815	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL56_03820	COG2207	Transcriptional regulator
AVL56_03820	COG3708	Transcriptional regulator
AVL56_03830	COG2239	Acts as a magnesium transporter
AVL56_03835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVL56_03845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVL56_03855	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AVL56_03860	COG1137	ATPase activity
AVL56_03875	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AVL56_03890	COG1127	ABC transporter
AVL56_03895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AVL56_03900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVL56_03905	COG2854	intermembrane phospholipid transfer
AVL56_03915	COG5007	Belongs to the BolA IbaG family
AVL56_03925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVL56_03930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVL56_03940	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AVL56_03955	COG2207	Transcriptional regulator
AVL56_03970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVL56_03985	COG5001	Diguanylate cyclase
AVL56_03985	COG3300	MHYT domain
AVL56_03990	COG2205	protein histidine kinase activity
AVL56_03990	COG0784	Response regulator, receiver
AVL56_04000	COG2207	Transcriptional regulator
AVL56_04005	COG1979	alcohol dehydrogenase
AVL56_04030	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AVL56_04040	COG0126	phosphoglycerate kinase activity
AVL56_04045	COG3588	fructose-bisphosphate aldolase
AVL56_04050	COG1506	peptidase
AVL56_04050	COG4946	Tricorn protease homolog
AVL56_04050	COG0823	Involved in the tonB-independent uptake of proteins
AVL56_04055	COG0248	Ppx GppA phosphatase
AVL56_04060	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AVL56_04070	COG0573	inorganic phosphate transmembrane transporter activity
AVL56_04075	COG0581	inorganic phosphate transmembrane transporter activity
AVL56_04080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AVL56_04090	COG0306	phosphate transporter
AVL56_04100	COG0583	DNA-binding transcription factor activity
AVL56_04125	COG1272	protein, Hemolysin III
AVL56_04145	COG0477	Major facilitator Superfamily
AVL56_04150	COG1609	Transcriptional regulator
AVL56_04150	COG2207	Transcriptional regulator
AVL56_04155	COG1070	Carbohydrate kinase
AVL56_04160	COG2115	Belongs to the xylose isomerase family
AVL56_04165	COG3291	Pkd domain containing protein
AVL56_04165	COG4447	cellulose binding
AVL56_04165	COG5520	Belongs to the glycosyl hydrolase 30 family
AVL56_04170	COG2207	Transcriptional regulator
AVL56_04185	COG1472	Belongs to the glycosyl hydrolase 3 family
AVL56_04190	COG1846	Transcriptional regulator
AVL56_04195	COG1764	response to oxidative stress
AVL56_04210	COG1739	Uncharacterized protein family UPF0029
AVL56_04220	COG0420	3'-5' exonuclease activity
AVL56_04225	COG0419	ATPase involved in DNA repair
AVL56_04230	COG3706	GGDEF domain
AVL56_04240	COG2971	BadF BadG BcrA BcrD
AVL56_04245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AVL56_04255	COG0488	(ABC) transporter
AVL56_04290	COG4667	esterase of the alpha-beta hydrolase superfamily
AVL56_04360	COG0582	viral genome integration into host DNA
AVL56_04420	COG2003	Belongs to the UPF0758 family
AVL56_04455	COG1346	cytolysis
AVL56_04485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVL56_04495	COG0513	Belongs to the DEAD box helicase family
AVL56_04505	COG3267	Type II secretory pathway component ExeA
AVL56_04505	COG3409	Peptidoglycan-binding domain 1 protein
AVL56_04515	COG3437	response regulator, receiver
AVL56_04515	COG0784	Response regulator, receiver
AVL56_04520	COG0066	3-isopropylmalate dehydratase activity
AVL56_04530	COG0473	3-isopropylmalate dehydrogenase activity
AVL56_04535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVL56_04565	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AVL56_04580	COG4555	ABC transporter
AVL56_04585	COG1668	transmembrane transport
AVL56_04605	COG4133	protoheme IX ABC transporter activity
AVL56_04610	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVL56_04615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVL56_04620	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVL56_04630	COG1138	Cytochrome C-type biogenesis protein
AVL56_04635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVL56_04650	COG2853	Lipoprotein
AVL56_04655	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVL56_04665	COG3104	oligopeptide transport
AVL56_04680	COG1682	transport, permease protein
AVL56_04710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AVL56_04715	COG1596	polysaccharide export
AVL56_04715	COG1555	photosystem II stabilization
AVL56_04720	COG0473	3-isopropylmalate dehydrogenase activity
AVL56_04735	COG1611	Belongs to the LOG family
AVL56_04740	COG3706	GGDEF domain
AVL56_04740	COG0745	RESPONSE REGULATOR receiver
AVL56_04745	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVL56_04745	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVL56_04815	COG0564	pseudouridine synthase activity
AVL56_04835	COG0024	Methionine aminopeptidase
AVL56_04840	COG0052	Belongs to the universal ribosomal protein uS2 family
AVL56_04850	COG0528	UMP kinase activity
AVL56_04860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AVL56_04865	COG0575	Belongs to the CDS family
AVL56_04870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AVL56_04875	COG0750	zinc metalloprotease
AVL56_04890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVL56_04895	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVL56_04910	COG0587	DNA-directed DNA polymerase activity
AVL56_04915	COG0825	malonyl-CoA metabolic process
AVL56_04920	COG0037	tRNA processing
AVL56_04940	COG0590	tRNA wobble adenosine to inosine editing
AVL56_04950	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVL56_04950	COG0047	phosphoribosylformylglycinamidine synthase activity
AVL56_04955	COG2840	Smr protein MutS2
AVL56_04985	COG0513	Belongs to the DEAD box helicase family
AVL56_04990	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AVL56_04995	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AVL56_05000	COG0583	DNA-binding transcription factor activity
AVL56_05020	COG1760	l-serine dehydratase
AVL56_05025	COG0494	nUDIX hydrolase
AVL56_05030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVL56_05040	COG1322	Protein conserved in bacteria
AVL56_05045	COG1404	Belongs to the peptidase S8 family
AVL56_05050	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AVL56_05055	COG0022	dehydrogenase e1 component
AVL56_05060	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVL56_05065	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AVL56_05070	COG0515	serine threonine protein kinase
AVL56_05075	COG1946	Acyl-CoA thioesterase
AVL56_05085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AVL56_05095	COG1956	GAF domain-containing protein
AVL56_05110	COG0793	Belongs to the peptidase S41A family
AVL56_05115	COG0733	neurotransmitter:sodium symporter activity
AVL56_05125	COG0308	aminopeptidase N
AVL56_05155	COG2902	Dehydrogenase
AVL56_05160	COG0167	dihydroorotate dehydrogenase activity
AVL56_05185	COG3130	regulation of translation
AVL56_05190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVL56_05200	COG0415	Belongs to the DNA photolyase family
AVL56_05205	COG0415	Belongs to the DNA photolyase family
AVL56_05210	COG3046	protein related to deoxyribodipyrimidine photolyase
AVL56_05235	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AVL56_05240	COG0589	response to stress
AVL56_05250	COG0069	glutamate synthase activity
AVL56_05265	COG2193	ferroxidase activity
AVL56_05275	COG3278	Belongs to the heme-copper respiratory oxidase family
AVL56_05290	COG2010	Cytochrome c
AVL56_05300	COG2217	Heavy metal translocating P-type atpase
AVL56_05315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVL56_05325	COG0037	tRNA processing
AVL56_05330	COG1752	Esterase of the alpha-beta hydrolase superfamily
AVL56_05395	COG1280	lysine exporter protein (LysE YggA)
AVL56_05400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AVL56_05405	COG2897	thiosulfate sulfurtransferase activity
AVL56_05410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AVL56_05460	COG0322	excinuclease ABC activity
AVL56_05465	COG2197	response regulator
AVL56_05470	COG1741	Belongs to the pirin family
AVL56_05480	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AVL56_05510	COG0642	Histidine kinase
AVL56_05515	COG0745	RESPONSE REGULATOR receiver
AVL56_05540	COG0670	Belongs to the BI1 family
AVL56_05550	COG2923	Belongs to the DsrF TusC family
AVL56_05560	COG2920	part of a sulfur-relay system
AVL56_05565	COG0561	phosphatase activity
AVL56_05580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVL56_05585	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AVL56_05590	COG1674	ftsk spoiiie
AVL56_05590	COG0531	amino acid
AVL56_05600	COG0686	Belongs to the AlaDH PNT family
AVL56_05605	COG0284	orotidine-5'-phosphate decarboxylase activity
AVL56_05610	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AVL56_05615	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AVL56_05625	COG0776	regulation of translation
AVL56_05630	COG0539	negative regulation of cytoplasmic translation
AVL56_05635	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AVL56_05640	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AVL56_05645	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AVL56_05660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVL56_05665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVL56_05670	COG0633	Ferredoxin
AVL56_05675	COG5002	protein histidine kinase activity
AVL56_05705	COG0789	Transcriptional regulator
AVL56_05815	COG1131	(ABC) transporter
AVL56_05850	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AVL56_05855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVL56_05865	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AVL56_05875	COG4783	chaperone-mediated protein folding
AVL56_05885	COG1393	Belongs to the ArsC family
AVL56_05920	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AVL56_05955	COG0572	uridine kinase
AVL56_05960	COG3769	mannosylglycerate metabolic process
AVL56_05965	COG1215	transferase activity, transferring glycosyl groups
AVL56_05975	COG0303	'Molybdopterin
AVL56_05980	COG0534	Mate efflux family protein
AVL56_05995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVL56_06000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AVL56_06010	COG0405	Gamma-glutamyltransferase
AVL56_06015	COG1024	Enoyl-CoA hydratase
AVL56_06050	COG1448	Aminotransferase
AVL56_06055	COG1671	Belongs to the UPF0178 family
AVL56_06060	COG1028	Short-chain dehydrogenase reductase Sdr
AVL56_06070	COG1960	acyl-CoA dehydrogenase activity
AVL56_06075	COG1917	Cupin 2, conserved barrel domain protein
AVL56_06075	COG2207	Transcriptional regulator
AVL56_06125	COG0596	Alpha beta hydrolase
AVL56_06135	COG0716	FMN binding
AVL56_06155	COG3265	gluconokinase activity
AVL56_06160	COG1609	Transcriptional regulator
AVL56_06170	COG1984	allophanate hydrolase subunit 2
AVL56_06180	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AVL56_06185	COG2996	Protein conserved in bacteria
AVL56_06190	COG1765	OsmC-like protein
AVL56_06195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL56_06205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL56_06220	COG0436	Aminotransferase
AVL56_06225	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AVL56_06230	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AVL56_06240	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AVL56_06250	COG1238	metal cluster binding
AVL56_06295	COG4628	conserved protein (DUF2132)
AVL56_06305	COG0454	-acetyltransferase
AVL56_06310	COG1119	ATPase activity
AVL56_06320	COG1185	polyribonucleotide nucleotidyltransferase activity
AVL56_06345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVL56_06385	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVL56_06390	COG0149	triose-phosphate isomerase activity
AVL56_06395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVL56_06400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AVL56_06405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVL56_06410	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AVL56_06415	COG1534	Rna-binding protein
AVL56_06425	COG1067	ATP-dependent peptidase activity
AVL56_06430	COG0495	leucyl-tRNA aminoacylation
AVL56_06440	COG1466	dna polymerase III delta subunit
AVL56_06445	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AVL56_06450	COG0799	negative regulation of ribosome biogenesis
AVL56_06455	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AVL56_06460	COG0768	penicillin binding
AVL56_06465	COG0772	Belongs to the SEDS family
AVL56_06470	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AVL56_06475	COG1686	Belongs to the peptidase S11 family
AVL56_06480	COG2921	Belongs to the UPF0250 family
AVL56_06485	COG0321	lipoyl(octanoyl) transferase activity
AVL56_06490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AVL56_06500	COG0252	asparaginase activity
AVL56_06510	COG0778	Nitroreductase
AVL56_06525	COG0616	signal peptide processing
AVL56_06545	COG0492	ferredoxin-NADP+ reductase activity
AVL56_06550	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AVL56_06555	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AVL56_06560	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AVL56_06565	COG0542	response to heat
AVL56_06570	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AVL56_06575	COG1278	Cold shock
AVL56_06585	COG1187	pseudouridine synthase activity
AVL56_06590	COG0482	sulfurtransferase activity
AVL56_06595	COG2915	High frequency lysogenization protein hflD homolog
AVL56_06600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AVL56_06610	COG2850	peptidyl-arginine hydroxylation
AVL56_06625	COG0247	lactate metabolic process
AVL56_06625	COG0277	FAD linked oxidase domain protein
AVL56_06630	COG3123	guanosine phosphorylase activity
AVL56_06635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AVL56_06675	COG1695	Transcriptional regulator
AVL56_06690	COG1077	Cell shape determining protein MreB Mrl
AVL56_06720	COG3265	gluconokinase activity
AVL56_06730	COG1028	Short-chain dehydrogenase reductase Sdr
AVL56_06745	COG1609	Transcriptional regulator
AVL56_06750	COG0679	Auxin Efflux Carrier
AVL56_06770	COG0574	Belongs to the PEP-utilizing enzyme family
AVL56_06770	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AVL56_06790	COG1942	4-Oxalocrotonate Tautomerase
AVL56_06810	COG1714	RDD family
AVL56_06830	COG3706	GGDEF domain
AVL56_06830	COG0745	RESPONSE REGULATOR receiver
AVL56_06835	COG0702	epimerase
AVL56_06845	COG0084	hydrolase, TatD family'
AVL56_06850	COG0470	DNA polymerase III
AVL56_06860	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AVL56_06865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVL56_06870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVL56_06875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVL56_06890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AVL56_06895	COG0416	fatty acid biosynthetic process
AVL56_06905	COG1399	metal-binding, possibly nucleic acid-binding protein
AVL56_06910	COG0424	maF-like protein
AVL56_06915	COG0546	phosphoglycolate phosphatase activity
AVL56_06925	COG1530	ribonuclease E activity
AVL56_06945	COG2153	protein acetylation
AVL56_06965	COG0625	glutathione transferase activity
AVL56_06980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AVL56_06990	COG0583	DNA-binding transcription factor activity
AVL56_07000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AVL56_07005	COG3724	N-succinylarginine dihydrolase activity
AVL56_07015	COG1301	dicarboxylic acid transport
AVL56_07020	COG4591	ABC-type transport system involved in lipoprotein release permease component
AVL56_07025	COG1136	(ABC) transporter
AVL56_07030	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AVL56_07060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AVL56_07065	COG0328	RNA-DNA hybrid ribonuclease activity
AVL56_07090	COG1643	Atp-dependent helicase
AVL56_07130	COG4999	Histidine kinase
AVL56_07130	COG3850	Histidine kinase
AVL56_07130	COG3437	response regulator, receiver
AVL56_07130	COG2205	protein histidine kinase activity
AVL56_07135	COG2925	Exonuclease
AVL56_07150	COG0183	Belongs to the thiolase family
AVL56_07155	COG0789	Transcriptional regulator
AVL56_07160	COG1960	acyl-CoA dehydrogenase activity
AVL56_07165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AVL56_07170	COG1024	Enoyl-CoA hydratase
AVL56_07205	COG1957	nucleoside hydrolase
AVL56_07220	COG2814	Major facilitator Superfamily
AVL56_07255	COG0708	Exodeoxyribonuclease III
AVL56_07275	COG4591	ABC-type transport system involved in lipoprotein release permease component
AVL56_07285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AVL56_07295	COG2096	Adenosyltransferase
AVL56_07305	COG1472	Belongs to the glycosyl hydrolase 3 family
AVL56_07315	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AVL56_07330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL56_07330	COG0072	phenylalanine-tRNA ligase activity
AVL56_07345	COG2755	lipolytic protein G-D-S-L family
AVL56_07345	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AVL56_07350	COG2755	lipolytic protein G-D-S-L family
AVL56_07350	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AVL56_07365	COG0438	transferase activity, transferring glycosyl groups
AVL56_07385	COG0438	transferase activity, transferring glycosyl groups
AVL56_07395	COG1216	Glycosyl transferase, family 2
AVL56_07410	COG0438	transferase activity, transferring glycosyl groups
AVL56_07445	COG4464	protein tyrosine phosphatase activity
AVL56_07450	COG0489	protein tyrosine kinase activity
AVL56_07455	COG1596	polysaccharide export
AVL56_07485	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AVL56_07495	COG1028	Short-chain dehydrogenase reductase Sdr
AVL56_07525	COG0154	amidase activity
AVL56_07535	COG0730	response to heat
AVL56_07540	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AVL56_07555	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AVL56_07560	COG2233	PERMEase
AVL56_07575	COG5002	protein histidine kinase activity
AVL56_07575	COG0784	Response regulator, receiver
AVL56_07580	COG3706	GGDEF domain
AVL56_07580	COG0745	RESPONSE REGULATOR receiver
AVL56_07585	COG3300	MHYT domain
AVL56_07585	COG5001	Diguanylate cyclase
AVL56_07595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AVL56_07600	COG2252	PERMEase
AVL56_07615	COG1309	transcriptional regulator
AVL56_07625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVL56_07640	COG2351	hydroxyisourate hydrolase activity
AVL56_07645	COG0402	S-adenosylhomocysteine deaminase activity
AVL56_07655	COG3447	MASE1 domain protein
AVL56_07655	COG5001	Diguanylate cyclase
AVL56_07655	COG5002	protein histidine kinase activity
AVL56_07675	COG3706	GGDEF domain
AVL56_07690	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AVL56_07710	COG2211	Major facilitator Superfamily
AVL56_07710	COG2190	(PTS) system
AVL56_07715	COG1393	Belongs to the ArsC family
AVL56_07745	COG2988	succinylglutamate desuccinylase activity
AVL56_07755	COG0058	SHG alpha-glucan phosphorylase activity
AVL56_07760	COG0033	Phosphoglucomutase
AVL56_07765	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AVL56_07770	COG0714	Associated with various cellular activities
AVL56_07785	COG2116	formate transmembrane transporter activity
AVL56_07790	COG2815	serine threonine protein kinase
AVL56_07790	COG0515	serine threonine protein kinase
AVL56_07795	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AVL56_07820	COG0583	DNA-binding transcription factor activity
AVL56_07835	COG3094	Invasion gene expression up-regulator, SirB
AVL56_07840	COG3437	response regulator, receiver
AVL56_07840	COG0784	Response regulator, receiver
AVL56_07845	COG2890	protein-(glutamine-N5) methyltransferase activity
AVL56_07855	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AVL56_07860	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AVL56_07865	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AVL56_07875	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AVL56_07880	COG3300	MHYT domain
AVL56_07880	COG5001	Diguanylate cyclase
AVL56_07890	COG1064	alcohol dehydrogenase
AVL56_07905	COG0012	GTP binding
AVL56_07910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AVL56_07935	COG1115	amino acid carrier protein
AVL56_07940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVL56_07955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVL56_07965	COG1702	phosphate starvation-inducible protein PhoH
AVL56_07975	COG4535	Mg2 and Co2 transporter CorC
AVL56_07980	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AVL56_07985	COG0280	phosphate acetyltransferase
AVL56_07985	COG0857	belongs to the CobB CobQ family
AVL56_07990	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AVL56_07995	COG0071	Belongs to the small heat shock protein (HSP20) family
AVL56_08020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVL56_08025	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AVL56_08030	COG0505	Belongs to the CarA family
AVL56_08035	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AVL56_08050	COG5001	Diguanylate cyclase
AVL56_08050	COG4251	negative regulation of phosphorylation
AVL56_08050	COG3706	GGDEF domain
AVL56_08050	COG2203	Gaf domain
AVL56_08055	COG3909	cytochrome
AVL56_08060	COG0484	heat shock protein binding
AVL56_08070	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AVL56_08075	COG0784	Response regulator, receiver
AVL56_08075	COG2205	protein histidine kinase activity
AVL56_08085	COG4771	TonB-dependent receptor
AVL56_08090	COG2610	gluconate transmembrane transporter activity
AVL56_08095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AVL56_08105	COG1028	Short-chain dehydrogenase reductase Sdr
AVL56_08115	COG0497	DNA recombination
AVL56_08120	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVL56_08125	COG0500	methyltransferase
AVL56_08130	COG2733	membrane
AVL56_08145	COG0110	maltose O-acetyltransferase activity
AVL56_08150	COG0656	L-ascorbic acid biosynthetic process
AVL56_08165	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AVL56_08170	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AVL56_08175	COG0009	L-threonylcarbamoyladenylate synthase
AVL56_08180	COG0613	PHP domain protein
AVL56_08185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVL56_08190	COG0512	Glutamine amidotransferase of anthranilate synthase
AVL56_08195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVL56_08200	COG0134	indole-3-glycerol-phosphate synthase activity
AVL56_08200	COG0135	phosphoribosylanthranilate isomerase activity
AVL56_08210	COG0159	tryptophan synthase activity
AVL56_08215	COG2350	Protein conserved in bacteria
AVL56_08230	COG0745	RESPONSE REGULATOR receiver
AVL56_08235	COG2205	protein histidine kinase activity
AVL56_08240	COG0628	permease
AVL56_08245	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AVL56_08250	COG1090	epimerase
AVL56_08255	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AVL56_08260	COG4181	ATPase activity
AVL56_08280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVL56_08305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVL56_08325	COG0745	RESPONSE REGULATOR receiver
AVL56_08335	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AVL56_08340	COG5265	(ABC) transporter
AVL56_08355	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AVL56_08365	COG4139	cobalamin transport
AVL56_08370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AVL56_08385	COG1073	alpha beta
AVL56_08385	COG2226	methyltransferase
AVL56_08390	COG0156	8-amino-7-oxononanoate synthase activity
AVL56_08415	COG0456	acetyltransferase
AVL56_08420	COG0189	ligase activity
AVL56_08435	COG0017	Asparaginyl-tRNA synthetase
AVL56_08445	COG2995	paraquat-inducible protein a
AVL56_08450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVL56_08450	COG3008	intermembrane lipid transfer
AVL56_08460	COG3706	GGDEF domain
AVL56_08480	COG0583	DNA-binding transcription factor activity
AVL56_08485	COG1309	transcriptional regulator
AVL56_08495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL56_08500	COG0517	IMP dehydrogenase activity
AVL56_08515	COG0583	DNA-binding transcription factor activity
AVL56_08520	COG3038	cytochrome b561
AVL56_08530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVL56_08560	COG2271	Major facilitator Superfamily
AVL56_08565	COG0784	Response regulator, receiver
AVL56_08565	COG2205	protein histidine kinase activity
AVL56_08605	COG0024	Methionine aminopeptidase
AVL56_08615	COG3706	GGDEF domain
AVL56_08615	COG0745	RESPONSE REGULATOR receiver
AVL56_08640	COG3459	Glycosyltransferase 36 associated
AVL56_08655	COG0330	HflC and HflK could
AVL56_08660	COG2199	diguanylate cyclase activity
AVL56_08660	COG2203	Gaf domain
AVL56_08670	COG2207	Transcriptional regulator
AVL56_08670	COG1917	Cupin 2, conserved barrel domain protein
AVL56_08700	COG4771	TonB-dependent receptor
AVL56_08725	COG4771	TonB-dependent receptor
AVL56_08730	COG1609	Transcriptional regulator
AVL56_08760	COG0583	DNA-binding transcription factor activity
AVL56_08765	COG3384	dioxygenase
AVL56_08815	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AVL56_08850	COG0667	Aldo Keto reductase
AVL56_08875	COG2159	amidohydrolase
AVL56_08880	COG2828	Protein conserved in bacteria
AVL56_08885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVL56_08900	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AVL56_08920	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AVL56_08925	COG2885	chlorophyll binding
AVL56_08930	COG0823	Involved in the tonB-independent uptake of proteins
AVL56_08945	COG0811	peptide transport
AVL56_08950	COG0824	Thioesterase
AVL56_08955	COG2255	four-way junction helicase activity
AVL56_08970	COG0494	nUDIX hydrolase
AVL56_08975	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AVL56_08990	COG2204	response regulator
AVL56_09000	COG2205	protein histidine kinase activity
AVL56_09020	COG0745	RESPONSE REGULATOR receiver
AVL56_09020	COG3706	GGDEF domain
AVL56_09030	COG0023	Translation Initiation Factor
AVL56_09035	COG0745	RESPONSE REGULATOR receiver
AVL56_09040	COG0077	Prephenate dehydratase
AVL56_09040	COG1605	Chorismate mutase
AVL56_09045	COG0840	transmembrane signaling receptor activity
AVL56_09050	COG0287	Prephenate dehydrogenase
AVL56_09050	COG1605	Chorismate mutase
AVL56_09055	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AVL56_09060	COG2860	membrane
AVL56_09075	COG0335	large ribosomal subunit rRNA binding
AVL56_09080	COG0336	Belongs to the RNA methyltransferase TrmD family
AVL56_09085	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AVL56_09090	COG0228	four-way junction DNA binding
AVL56_09110	COG1132	(ABC) transporter
AVL56_09115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL56_09125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AVL56_09155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AVL56_09160	COG4137	Cytochrome C assembly protein
AVL56_09165	COG4536	flavin adenine dinucleotide binding
AVL56_09175	COG2062	phosphohistidine phosphatase, SixA
AVL56_09180	COG1025	Belongs to the peptidase M16 family
AVL56_09195	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVL56_09195	COG1024	Enoyl-CoA hydratase
AVL56_09205	COG0714	Associated with various cellular activities
AVL56_09225	COG2304	oxidoreductase activity
AVL56_09250	COG3706	GGDEF domain
AVL56_09255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVL56_09260	COG0175	sulfate reduction
AVL56_09265	COG0529	Catalyzes the synthesis of activated sulfate
AVL56_09280	COG0471	metal ion transport
AVL56_09280	COG3273	potassium ion transport
AVL56_09305	COG0367	asparagine synthase
AVL56_09315	COG0602	queuosine metabolic process
AVL56_09340	COG0556	nucleotide-excision repair
AVL56_09345	COG0534	Mate efflux family protein
AVL56_09360	COG4657	Part of a membrane complex involved in electron transport
AVL56_09365	COG2878	Part of a membrane complex involved in electron transport
AVL56_09370	COG4656	Part of a membrane complex involved in electron transport
AVL56_09375	COG4658	electron transport chain
AVL56_09385	COG4660	Part of a membrane complex involved in electron transport
AVL56_09390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AVL56_09410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AVL56_09415	COG0823	Involved in the tonB-independent uptake of proteins
AVL56_09415	COG1506	peptidase
AVL56_09415	COG4946	Tricorn protease homolog
AVL56_09440	COG1278	Cold shock
AVL56_09445	COG0346	lactoylglutathione lyase activity
AVL56_09450	COG0584	glycerophosphoryl diester phosphodiesterase
AVL56_09455	COG2885	chlorophyll binding
AVL56_09460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AVL56_09465	COG0450	alkyl hydroperoxide reductase
AVL56_09490	COG4771	TonB-dependent receptor
AVL56_09495	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AVL56_09505	COG2766	serine protein kinase
AVL56_09510	COG2718	Belongs to the UPF0229 family
AVL56_09515	COG2719	SpoVR family
AVL56_09535	COG2890	protein-(glutamine-N5) methyltransferase activity
AVL56_09540	COG2840	Smr protein MutS2
AVL56_09565	COG1136	(ABC) transporter
AVL56_09590	COG0612	Peptidase, M16
AVL56_09600	COG0564	pseudouridine synthase activity
AVL56_09605	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AVL56_09610	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AVL56_09635	COG2175	clavaminate synthase activity
AVL56_09665	COG0583	DNA-binding transcription factor activity
AVL56_09680	COG0456	acetyltransferase
AVL56_09720	COG1444	tRNA N-acetyltransferase activity
AVL56_09735	COG0848	biopolymer transport protein
AVL56_09740	COG0811	peptide transport
AVL56_09745	COG0811	peptide transport
AVL56_09805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AVL56_09810	COG1522	sequence-specific DNA binding
AVL56_09815	COG0625	glutathione transferase activity
AVL56_09845	COG1842	Phage shock protein A
AVL56_09850	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AVL56_09855	COG0747	negative chemotaxis
AVL56_09860	COG4168	peptide transport system, permease
AVL56_09865	COG4171	peptide transport system, permease
AVL56_09870	COG4172	Belongs to the ABC transporter superfamily
AVL56_09875	COG4172	Belongs to the ABC transporter superfamily
AVL56_09880	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AVL56_09895	COG1607	acyl-coa hydrolase
AVL56_09935	COG3590	peptidase
AVL56_09940	COG1309	transcriptional regulator
AVL56_09950	COG0659	secondary active sulfate transmembrane transporter activity
AVL56_09955	COG0288	reversible hydration of carbon dioxide
AVL56_09960	COG0583	DNA-binding transcription factor activity
AVL56_09965	COG0583	DNA-binding transcription factor activity
AVL56_09975	COG0646	methionine synthase
AVL56_09975	COG1410	methionine synthase
AVL56_09980	COG0646	methionine synthase
AVL56_09980	COG1410	methionine synthase
AVL56_09995	COG0835	chemotaxis
AVL56_10005	COG1192	Involved in chromosome partitioning
AVL56_10010	COG2201	protein-glutamate methylesterase activity
AVL56_10015	COG2198	Histidine kinase
AVL56_10015	COG0643	Histidine kinase
AVL56_10020	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AVL56_10035	COG0455	bacterial-type flagellum organization
AVL56_10045	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVL56_10060	COG1987	bacterial-type flagellum assembly
AVL56_10110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVL56_10115	COG1766	The M ring may be actively involved in energy transduction
AVL56_10125	COG2204	response regulator
AVL56_10130	COG3852	Histidine kinase
AVL56_10135	COG2204	response regulator
AVL56_10145	COG1086	Polysaccharide biosynthesis protein
AVL56_10150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVL56_10155	COG1083	cytidylyl-transferase
AVL56_10165	COG2089	acid synthase
AVL56_10180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVL56_10185	COG1028	Short-chain dehydrogenase reductase Sdr
AVL56_10190	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AVL56_10220	COG2089	acid synthase
AVL56_10225	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVL56_10230	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AVL56_10270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVL56_10275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVL56_10295	COG1256	bacterial-type flagellum assembly
AVL56_10300	COG3951	Flagellar rod assembly protein muramidase FlgJ
AVL56_10300	COG1705	Flagellar rod assembly protein muramidase FlgJ
AVL56_10315	COG4786	Flagellar basal body rod
AVL56_10320	COG4787	bacterial-type flagellum-dependent cell motility
AVL56_10325	COG1749	Flagellar hook protein flgE
AVL56_10330	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AVL56_10335	COG1558	bacterial-type flagellum-dependent cell motility
AVL56_10340	COG1815	bacterial-type flagellum-dependent cell motility
AVL56_10345	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AVL56_10350	COG0784	Response regulator, receiver
AVL56_10350	COG0835	chemotaxis
AVL56_10390	COG2197	response regulator
AVL56_10395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL56_10405	COG2885	chlorophyll binding
AVL56_10520	COG2205	protein histidine kinase activity
AVL56_10520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVL56_10530	COG0205	6-phosphofructokinase activity
AVL56_10535	COG3279	Response regulator of the LytR AlgR family
AVL56_10540	COG3275	phosphorelay sensor kinase activity
AVL56_10570	COG3081	Nucleoid-associated protein
AVL56_10575	COG3082	Protein of unknown function (DUF1414)
AVL56_10580	COG3083	sulfuric ester hydrolase activity
AVL56_10590	COG2226	methyltransferase
AVL56_10595	COG1024	Enoyl-CoA hydratase
AVL56_10600	COG1960	acyl-CoA dehydrogenase activity
AVL56_10610	COG2084	Dehydrogenase
AVL56_10615	COG0386	Belongs to the glutathione peroxidase family
AVL56_10620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVL56_10625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AVL56_10630	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AVL56_10655	COG0616	signal peptide processing
AVL56_10665	COG2267	carboxylic ester hydrolase activity
AVL56_10670	COG1028	Short-chain dehydrogenase reductase Sdr
AVL56_10680	COG1609	Transcriptional regulator
AVL56_10695	COG0366	Alpha amylase catalytic
AVL56_10715	COG4667	esterase of the alpha-beta hydrolase superfamily
AVL56_10750	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVL56_10755	COG0567	Dehydrogenase, E1 component
AVL56_10765	COG1053	succinate dehydrogenase
AVL56_10770	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AVL56_10775	COG2009	succinate dehydrogenase
AVL56_10795	COG0435	Glutathione S-transferase
AVL56_10800	COG0579	oxidoreductase
AVL56_10805	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AVL56_10850	COG1663	tetraacyldisaccharide 4'-kinase activity
AVL56_10855	COG1132	(ABC) transporter
AVL56_10870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVL56_10880	COG1196	nuclear chromosome segregation
AVL56_10900	COG0295	cytidine deaminase activity
AVL56_10925	COG0477	Major facilitator Superfamily
AVL56_10945	COG2318	DinB family
AVL56_10950	COG0457	Tetratricopeptide repeat
AVL56_10960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AVL56_10970	COG2914	Belongs to the UPF0125 (RnfH) family
AVL56_10975	COG2867	negative regulation of translational initiation
AVL56_11035	COG4771	TonB-dependent receptor
AVL56_11040	COG2814	Major facilitator Superfamily
AVL56_11070	COG1012	belongs to the aldehyde dehydrogenase family
AVL56_11080	COG1595	DNA-templated transcription, initiation
AVL56_11085	COG1595	DNA-templated transcription, initiation
AVL56_11115	COG0583	DNA-binding transcription factor activity
AVL56_11135	COG5001	Diguanylate cyclase
AVL56_11135	COG3300	MHYT domain
AVL56_11150	COG2203	Gaf domain
AVL56_11150	COG3706	GGDEF domain
AVL56_11150	COG4251	negative regulation of phosphorylation
AVL56_11150	COG5001	Diguanylate cyclase
AVL56_11165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AVL56_11170	COG4136	ATPase activity
AVL56_11175	COG4135	transport system, permease component
AVL56_11195	COG4771	TonB-dependent receptor
AVL56_11210	COG1032	radical SAM domain protein
AVL56_11235	COG4774	siderophore transport
AVL56_11245	COG0450	alkyl hydroperoxide reductase
AVL56_11275	COG3153	acetyltransferase
AVL56_11275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVL56_11285	COG0596	Alpha beta hydrolase
AVL56_11290	COG3706	GGDEF domain
AVL56_11300	COG4269	membrane
AVL56_11310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AVL56_11325	COG0195	Participates in both transcription termination and antitermination
AVL56_11335	COG3437	response regulator, receiver
AVL56_11340	COG0784	Response regulator, receiver
AVL56_11340	COG2198	Histidine kinase
AVL56_11340	COG2205	protein histidine kinase activity
AVL56_11360	COG4771	TonB-dependent receptor
AVL56_11365	COG0668	transmembrane transport
AVL56_11385	COG0668	transmembrane transport
AVL56_11405	COG0246	Mannitol dehydrogenase
AVL56_11415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVL56_11420	COG2390	Transcriptional regulator
AVL56_11430	COG0596	Alpha beta hydrolase
AVL56_11435	COG1960	acyl-CoA dehydrogenase activity
AVL56_11440	COG0183	Belongs to the thiolase family
AVL56_11445	COG1024	Enoyl-CoA hydratase
AVL56_11445	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVL56_11450	COG0596	Alpha beta hydrolase
AVL56_11480	COG1960	acyl-CoA dehydrogenase activity
AVL56_11490	COG4771	TonB-dependent receptor
AVL56_11510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVL56_11530	COG0314	molybdopterin synthase activity
AVL56_11535	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AVL56_11540	COG0315	cyclic pyranopterin monophosphate synthase activity
AVL56_11545	COG0521	Mo-molybdopterin cofactor biosynthetic process
AVL56_11550	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AVL56_11675	COG1028	Short-chain dehydrogenase reductase Sdr
AVL56_11715	COG3268	Saccharopine dehydrogenase
AVL56_11730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVL56_11745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVL56_11750	COG1074	ATP-dependent DNA helicase activity
AVL56_11755	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AVL56_11765	COG1022	Amp-dependent synthetase and ligase
AVL56_11770	COG3300	MHYT domain
AVL56_11770	COG5001	Diguanylate cyclase
AVL56_11795	COG0583	DNA-binding transcription factor activity
AVL56_11815	COG0640	Transcriptional regulator
AVL56_11825	COG0583	DNA-binding transcription factor activity
AVL56_11835	COG2204	response regulator
AVL56_11845	COG4251	negative regulation of phosphorylation
AVL56_11850	COG0784	Response regulator, receiver
AVL56_11880	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AVL56_11905	COG3139	Protein of unknown function (DUF1315)
AVL56_11915	COG1115	amino acid carrier protein
AVL56_11920	COG2866	Carboxypeptidase
AVL56_11940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AVL56_11950	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AVL56_11955	COG1640	4-alpha-glucanotransferase
AVL56_11965	COG0676	glucose-6-phosphate 1-epimerase activity
AVL56_11970	COG0800	Aldolase
AVL56_11980	COG0129	dihydroxy-acid dehydratase activity
AVL56_11990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AVL56_11995	COG1737	Transcriptional regulator
AVL56_12000	COG0469	pyruvate kinase activity
AVL56_12005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AVL56_12050	COG2205	protein histidine kinase activity
AVL56_12055	COG0745	RESPONSE REGULATOR receiver
AVL56_12080	COG3665	Urea carboxylase-associated protein
AVL56_12090	COG1028	Short-chain dehydrogenase reductase Sdr
AVL56_12095	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AVL56_12120	COG2721	sulfolactate sulfo-lyase activity
AVL56_12125	COG1904	glucuronate isomerase
AVL56_12130	COG0246	Mannitol dehydrogenase
AVL56_12135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVL56_12140	COG2755	lipolytic protein G-D-S-L family
AVL56_12150	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AVL56_12160	COG4677	pectinesterase activity
AVL56_12180	COG2356	endonuclease I
AVL56_12190	COG1024	Enoyl-CoA hydratase
AVL56_12210	COG1609	Transcriptional regulator
AVL56_12215	COG4948	Mandelate Racemase Muconate Lactonizing
AVL56_12220	COG0673	inositol 2-dehydrogenase activity
AVL56_12250	COG0746	molybdenum cofactor guanylyltransferase activity
AVL56_12260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVL56_12265	COG1764	response to oxidative stress
AVL56_12280	COG3706	GGDEF domain
AVL56_12290	COG0745	RESPONSE REGULATOR receiver
AVL56_12295	COG3850	Histidine kinase
AVL56_12295	COG5002	protein histidine kinase activity
AVL56_12325	COG1957	nucleoside hydrolase
AVL56_12330	COG0738	Major facilitator superfamily
AVL56_12355	COG0840	transmembrane signaling receptor activity
AVL56_12365	COG0753	catalase activity
AVL56_12375	COG0330	HflC and HflK could
AVL56_12395	COG0778	Nitroreductase
AVL56_12415	COG0471	metal ion transport
AVL56_12425	COG0489	protein tyrosine kinase activity
AVL56_12430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL56_12430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL56_12435	COG2226	methyltransferase
AVL56_12440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVL56_12445	COG1388	LysM domain
AVL56_12445	COG0741	lytic transglycosylase activity
AVL56_12465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AVL56_12470	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVL56_12480	COG2268	Band 7 protein
AVL56_12500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVL56_12505	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVL56_12510	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AVL56_12515	COG2080	2 iron, 2 sulfur cluster binding
AVL56_12525	COG0604	alcohol dehydrogenase
AVL56_12535	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AVL56_12550	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AVL56_12555	COG1286	toxin biosynthetic process
AVL56_12560	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AVL56_12565	COG0285	dihydrofolate synthase activity
AVL56_12575	COG0101	tRNA pseudouridine synthase activity
AVL56_12590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVL56_12610	COG3706	GGDEF domain
AVL56_12615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVL56_12615	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AVL56_12645	COG3101	peptidyl-lysine hydroxylation
AVL56_12690	COG1902	pentaerythritol trinitrate reductase activity
AVL56_12690	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVL56_12715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVL56_12720	COG1309	transcriptional regulator
AVL56_12725	COG4399	Belongs to the UPF0754 family
AVL56_12760	COG2186	Transcriptional regulator
AVL56_12770	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AVL56_12775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVL56_12780	COG2983	Belongs to the UPF0260 family
AVL56_12785	COG0179	Fumarylacetoacetate (FAA) hydrolase
AVL56_12800	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AVL56_12805	COG0318	PFAM AMP-dependent synthetase and ligase
AVL56_12810	COG2267	carboxylic ester hydrolase activity
AVL56_12825	COG1214	PFAM Peptidase M22, glycoprotease
AVL56_12830	COG1199	ATP-dependent helicase activity
AVL56_12890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AVL56_12895	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AVL56_12900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVL56_12905	COG0131	Imidazoleglycerol-phosphate dehydratase
AVL56_12905	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AVL56_12910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AVL56_12925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AVL56_12925	COG0140	phosphoribosyl-ATP diphosphatase activity
AVL56_12935	COG1028	Short-chain dehydrogenase reductase Sdr
AVL56_12945	COG1022	Amp-dependent synthetase and ligase
AVL56_12965	COG0463	Glycosyl transferase, family 2
AVL56_12985	COG0642	Histidine kinase
AVL56_12990	COG0745	RESPONSE REGULATOR receiver
AVL56_12995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVL56_13020	COG0326	Molecular chaperone. Has ATPase activity
AVL56_13025	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AVL56_13050	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AVL56_13055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVL56_13065	COG3220	belongs to the UPF0276 family
AVL56_13075	COG4249	Peptidase C14 caspase catalytic subunit p20
AVL56_13075	COG2319	Wd-40 repeat
AVL56_13085	COG4251	negative regulation of phosphorylation
AVL56_13085	COG5001	Diguanylate cyclase
AVL56_13085	COG3706	GGDEF domain
AVL56_13085	COG2203	Gaf domain
AVL56_13120	COG1183	phosphatidylcholine synthase activity
AVL56_13140	COG0542	response to heat
AVL56_13150	COG0564	pseudouridine synthase activity
AVL56_13165	COG1595	DNA-templated transcription, initiation
AVL56_13180	COG4221	oxidoreductase activity
AVL56_13195	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVL56_13205	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AVL56_13210	COG1722	exodeoxyribonuclease VII activity
AVL56_13215	COG0142	geranyltranstransferase activity
AVL56_13225	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AVL56_13230	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AVL56_13240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AVL56_13255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVL56_13255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVL56_13270	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVL56_13275	COG0488	(ABC) transporter
AVL56_13285	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AVL56_13295	COG0560	Phosphoserine phosphatase
AVL56_13305	COG0084	hydrolase, TatD family'
AVL56_13325	COG0681	Belongs to the peptidase S26 family
AVL56_13350	COG1595	DNA-templated transcription, initiation
AVL56_13355	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AVL56_13370	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AVL56_13390	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AVL56_13450	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AVL56_13455	COG1047	Peptidyl-prolyl cis-trans
AVL56_13465	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AVL56_13470	COG0196	riboflavin kinase activity
AVL56_13475	COG0728	peptidoglycan biosynthetic process
AVL56_13480	COG0268	Binds directly to 16S ribosomal RNA
AVL56_13495	COG1028	Short-chain dehydrogenase reductase Sdr
AVL56_13500	COG0385	Bile acid
AVL56_13530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVL56_13535	COG0776	regulation of translation
AVL56_13540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVL56_13545	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AVL56_13550	COG0740	serine-type endopeptidase activity
AVL56_13555	COG0544	peptidyl-prolyl cis-trans isomerase activity
AVL56_13595	COG1720	tRNA m6t6A37 methyltransferase activity
AVL56_13610	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AVL56_13615	COG0123	including yeast histone deacetylase and acetoin utilization protein
AVL56_13635	COG0516	GMP reductase activity
AVL56_13635	COG0517	IMP dehydrogenase activity
AVL56_13640	COG1570	exodeoxyribonuclease VII activity
AVL56_13655	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVL56_13660	COG2976	Protein conserved in bacteria
AVL56_13685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AVL56_13695	COG2166	iron-sulfur cluster assembly
AVL56_13710	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVL56_13715	COG0719	Fe-S assembly protein
AVL56_13720	COG0396	ATPase activity
AVL56_13725	COG0719	Fe-S assembly protein
AVL56_13730	COG1104	cysteine desulfurase activity
AVL56_13745	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AVL56_13750	COG0483	inositol monophosphate 1-phosphatase activity
AVL56_13780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVL56_13785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVL56_13790	COG1862	Preprotein translocase
AVL56_13795	COG0343	queuine tRNA-ribosyltransferase activity
AVL56_13810	COG3789	protein conserved in bacteria
AVL56_13815	COG1842	Phage shock protein A
AVL56_13840	COG0754	glutathionylspermidine amidase activity
AVL56_13855	COG2066	Belongs to the glutaminase family
AVL56_13860	COG1785	Belongs to the alkaline phosphatase family
AVL56_13915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AVL56_13920	COG1045	serine acetyltransferase
AVL56_13945	COG0438	transferase activity, transferring glycosyl groups
AVL56_13990	COG0463	Glycosyl transferase, family 2
AVL56_13990	COG1216	Glycosyl transferase, family 2
AVL56_14025	COG0489	protein tyrosine kinase activity
AVL56_14035	COG3267	Type II secretory pathway component ExeA
AVL56_14035	COG3409	Peptidoglycan-binding domain 1 protein
AVL56_14040	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AVL56_14040	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AVL56_14045	COG2827	Endonuclease containing a URI domain
AVL56_14065	COG1560	Kdo2-lipid A biosynthetic process
AVL56_14095	COG1960	acyl-CoA dehydrogenase activity
AVL56_14110	COG1435	thymidine kinase activity
AVL56_14120	COG1609	Transcriptional regulator
AVL56_14125	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AVL56_14165	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AVL56_14170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVL56_14175	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AVL56_14180	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AVL56_14205	COG0515	serine threonine protein kinase
AVL56_14205	COG2815	serine threonine protein kinase
AVL56_14235	COG4774	siderophore transport
AVL56_14250	COG1028	Short-chain dehydrogenase reductase Sdr
AVL56_14255	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AVL56_14260	COG0789	Transcriptional regulator
AVL56_14275	COG0189	ligase activity
AVL56_14290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AVL56_14330	COG1960	acyl-CoA dehydrogenase activity
AVL56_14360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVL56_14370	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AVL56_14420	COG1607	acyl-coa hydrolase
AVL56_14425	COG0826	peptidase U32
AVL56_14500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AVL56_14540	COG1028	Short-chain dehydrogenase reductase Sdr
AVL56_14550	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AVL56_14555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVL56_14560	COG1845	cytochrome c oxidase, subunit III
AVL56_14570	COG0109	protoheme IX farnesyltransferase activity
AVL56_14585	COG0583	DNA-binding transcription factor activity
AVL56_14600	COG4221	oxidoreductase activity
AVL56_14605	COG0693	protein deglycase activity
AVL56_14635	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AVL56_14640	COG1335	isochorismatase
AVL56_14645	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AVL56_14700	COG1566	PFAM secretion protein HlyD family protein
AVL56_14705	COG1846	Transcriptional regulator
AVL56_14715	COG1295	ribonuclease BN
AVL56_14720	COG0514	ATP-dependent DNA helicase (RecQ)
AVL56_14725	COG4681	YaeQ
AVL56_14745	COG0583	DNA-binding transcription factor activity
AVL56_14755	COG0484	heat shock protein binding
AVL56_14780	COG4249	Peptidase C14 caspase catalytic subunit p20
AVL56_14780	COG2319	Wd-40 repeat
AVL56_14795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVL56_14815	COG1451	nucleotide metabolic process
AVL56_14830	COG0653	protein targeting
AVL56_14865	COG2133	pyrroloquinoline quinone binding
AVL56_14875	COG0697	spore germination
AVL56_14880	COG3813	Protein conserved in bacteria
AVL56_14885	COG0513	Belongs to the DEAD box helicase family
AVL56_14935	COG2814	Major facilitator Superfamily
AVL56_14945	COG0656	L-ascorbic acid biosynthetic process
AVL56_15000	COG0583	DNA-binding transcription factor activity
AVL56_15015	COG1621	beta-fructofuranosidase activity
AVL56_15020	COG0477	Major facilitator Superfamily
AVL56_15030	COG1629	transport
AVL56_15030	COG4206	TonB-dependent receptor
AVL56_15055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVL56_15060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVL56_15065	COG0006	proline dipeptidase activity
AVL56_15080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVL56_15095	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AVL56_15100	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AVL56_15105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVL56_15125	COG3313	Fe-S protein
AVL56_15165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVL56_15170	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVL56_15175	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AVL56_15180	COG2186	Transcriptional regulator
AVL56_15210	COG1459	type II secretion system
AVL56_15220	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AVL56_15220	COG0237	dephospho-CoA kinase activity
AVL56_15225	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AVL56_15235	COG2988	succinylglutamate desuccinylase activity
AVL56_15240	COG0494	nUDIX hydrolase
AVL56_15250	COG0739	heme binding
AVL56_15255	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AVL56_15265	COG0849	cell division
AVL56_15270	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AVL56_15275	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVL56_15280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVL56_15290	COG0772	Belongs to the SEDS family
AVL56_15295	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AVL56_15305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AVL56_15310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVL56_15315	COG0768	penicillin binding
AVL56_15320	COG3116	cell division
AVL56_15330	COG2001	Belongs to the MraZ family
AVL56_15370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVL56_15370	COG0678	peroxiredoxin activity
AVL56_15375	COG5001	Diguanylate cyclase
AVL56_15375	COG4251	negative regulation of phosphorylation
AVL56_15375	COG2203	Gaf domain
AVL56_15375	COG3706	GGDEF domain
AVL56_15390	COG5002	protein histidine kinase activity
AVL56_15390	COG0784	Response regulator, receiver
AVL56_15390	COG2198	Histidine kinase
AVL56_15410	COG0668	transmembrane transport
AVL56_15415	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AVL56_15420	COG0189	ligase activity
AVL56_15425	COG1678	Uncharacterized ACR, COG1678
AVL56_15430	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AVL56_15450	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AVL56_15455	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AVL56_15460	COG0762	integral membrane protein
AVL56_15475	COG1902	pentaerythritol trinitrate reductase activity
AVL56_15475	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVL56_15490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL56_15495	COG0625	glutathione transferase activity
AVL56_15525	COG0083	homoserine kinase activity
AVL56_15535	COG0583	DNA-binding transcription factor activity
AVL56_15545	COG2197	response regulator
AVL56_15550	COG4585	Histidine kinase
AVL56_15570	COG0640	Transcriptional regulator
AVL56_15580	COG0431	NADPH-dependent FMN reductase
AVL56_15585	COG0798	PFAM Bile acid sodium symporter
AVL56_15590	COG2201	protein-glutamate methylesterase activity
AVL56_15595	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AVL56_15600	COG0745	RESPONSE REGULATOR receiver
AVL56_15605	COG5002	protein histidine kinase activity
AVL56_15630	COG1748	Saccharopine dehydrogenase
AVL56_15645	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AVL56_15650	COG3107	peptidoglycan biosynthetic process
AVL56_15655	COG0792	nuclease activity
AVL56_15665	COG2823	Periplasmic or secreted lipoprotein
AVL56_15685	COG0583	DNA-binding transcription factor activity
AVL56_15700	COG4585	Histidine kinase
AVL56_15705	COG2197	response regulator
AVL56_15710	COG4771	TonB-dependent receptor
AVL56_15720	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AVL56_15725	COG0372	Belongs to the citrate synthase family
AVL56_15735	COG2828	Protein conserved in bacteria
AVL56_15740	COG2203	Gaf domain
AVL56_15740	COG2199	diguanylate cyclase activity
AVL56_15760	COG4206	TonB-dependent receptor
AVL56_15785	COG2198	Histidine kinase
AVL56_15785	COG5002	protein histidine kinase activity
AVL56_15785	COG0784	Response regulator, receiver
AVL56_15790	COG0070	glutamate synthase
AVL56_15790	COG0067	glutamate synthase
AVL56_15790	COG0069	glutamate synthase activity
AVL56_15795	COG0493	'glutamate synthase
AVL56_15805	COG1476	TRANSCRIPTIONal
AVL56_15820	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AVL56_15835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AVL56_15855	COG0739	heme binding
AVL56_15860	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AVL56_15870	COG0738	Major facilitator superfamily
AVL56_15880	COG1902	pentaerythritol trinitrate reductase activity
AVL56_15890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVL56_15895	COG0625	glutathione transferase activity
AVL56_15915	COG2894	cell division
AVL56_15920	COG0850	regulation of cytokinetic process
AVL56_15960	COG1914	H( )-stimulated, divalent metal cation uptake system
AVL56_15965	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AVL56_15985	COG0174	glutamine synthetase
AVL56_15995	COG3852	Histidine kinase
AVL56_16005	COG3437	response regulator, receiver
AVL56_16010	COG0204	Acyl-transferase
AVL56_16025	COG3706	GGDEF domain
AVL56_16040	COG0525	valine-tRNA ligase activity
AVL56_16045	COG2927	DNA polymerase III (CHI subunit)
AVL56_16050	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVL56_16055	COG0795	lipopolysaccharide-transporting ATPase activity
AVL56_16060	COG0795	lipopolysaccharide-transporting ATPase activity
AVL56_16110	COG4264	IucA IucC family
AVL56_16115	COG0318	PFAM AMP-dependent synthetase and ligase
AVL56_16125	COG1082	Xylose isomerase domain protein TIM barrel
AVL56_16165	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AVL56_16180	COG0251	oxidation-reduction process
AVL56_16225	COG4191	Histidine kinase
AVL56_16235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVL56_16265	COG3706	GGDEF domain
AVL56_16270	COG3706	GGDEF domain
AVL56_16300	COG4771	TonB-dependent receptor
AVL56_16305	COG1858	cytochrome C peroxidase
AVL56_16335	COG1028	Short-chain dehydrogenase reductase Sdr
AVL56_16345	COG1917	Cupin 2, conserved barrel domain protein
AVL56_16350	COG2271	Major facilitator Superfamily
AVL56_16370	COG1716	ATPase activity
AVL56_16405	COG1357	PFAM Pentapeptide repeats (8 copies)
AVL56_16405	COG0515	serine threonine protein kinase
AVL56_16420	COG0842	Transport permease protein
AVL56_16420	COG1131	(ABC) transporter
AVL56_16420	COG1716	ATPase activity
AVL56_16425	COG0513	Belongs to the DEAD box helicase family
AVL56_16430	COG0800	Aldolase
AVL56_16435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVL56_16440	COG2186	Transcriptional regulator
AVL56_16450	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AVL56_16450	COG3264	Mechanosensitive ion channel
AVL56_16485	COG3568	Endonuclease Exonuclease Phosphatase
AVL56_16500	COG0730	response to heat
AVL56_16520	COG4191	Histidine kinase
AVL56_16530	COG0417	DNA replication proofreading
AVL56_16580	COG1309	transcriptional regulator
AVL56_16595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVL56_16605	COG1573	uracil-dna glycosylase
AVL56_16610	COG3300	MHYT domain
AVL56_16610	COG5001	Diguanylate cyclase
AVL56_16630	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AVL56_16635	COG4771	TonB-dependent receptor
AVL56_16660	COG1842	Phage shock protein A
AVL56_16670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVL56_16695	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AVL56_16700	COG0204	Acyl-transferase
AVL56_16705	COG0204	Acyl-transferase
AVL56_16710	COG0668	transmembrane transport
AVL56_16725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVL56_16730	COG0733	neurotransmitter:sodium symporter activity
AVL56_16745	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVL56_16760	COG0716	FMN binding
AVL56_16770	COG0848	biopolymer transport protein
AVL56_16780	COG0457	Tetratricopeptide repeat
AVL56_16810	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AVL56_16815	COG0702	epimerase
AVL56_16830	COG5002	protein histidine kinase activity
AVL56_16830	COG5001	Diguanylate cyclase
AVL56_16840	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AVL56_16845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVL56_16855	COG0583	DNA-binding transcription factor activity
AVL56_16860	COG0121	glutamine amidotransferase
AVL56_16875	COG1522	sequence-specific DNA binding
AVL56_16890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVL56_16900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVL56_16910	COG1477	protein flavinylation
AVL56_16915	COG2871	sodium ion transport
AVL56_16920	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AVL56_16925	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AVL56_16930	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AVL56_16935	COG1805	sodium ion transport
AVL56_16945	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVL56_16950	COG0545	Peptidyl-prolyl cis-trans isomerase
AVL56_16955	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AVL56_16965	COG0039	L-malate dehydrogenase activity
AVL56_16970	COG1438	arginine binding
AVL56_17000	COG0572	uridine kinase
AVL56_17005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AVL56_17020	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AVL56_17030	COG0745	RESPONSE REGULATOR receiver
AVL56_17030	COG3706	GGDEF domain
AVL56_17040	COG0517	IMP dehydrogenase activity
AVL56_17040	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AVL56_17045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVL56_17065	COG0189	ligase activity
AVL56_17075	COG4067	protein conserved in archaea
AVL56_17075	COG0189	ligase activity
AVL56_17090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVL56_17105	COG1283	sodium-dependent phosphate transmembrane transporter activity
AVL56_17110	COG0667	Aldo Keto reductase
AVL56_17125	COG0753	catalase activity
AVL56_17160	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AVL56_17165	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AVL56_17165	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AVL56_17170	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AVL56_17225	COG0583	DNA-binding transcription factor activity
AVL56_17280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AVL56_17295	COG1216	Glycosyl transferase, family 2
AVL56_17295	COG0438	transferase activity, transferring glycosyl groups
AVL56_17325	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AVL56_17340	COG3119	arylsulfatase activity
AVL56_17355	COG0438	transferase activity, transferring glycosyl groups
AVL56_17355	COG1216	Glycosyl transferase, family 2
AVL56_17360	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AVL56_17360	COG0662	Cupin 2, conserved barrel domain protein
AVL56_17370	COG0202	RNA polymerase activity
AVL56_17390	COG0201	protein transport
AVL56_17410	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AVL56_17445	COG0784	Response regulator, receiver
AVL56_17445	COG5002	protein histidine kinase activity
AVL56_17465	COG0557	exoribonuclease II activity
AVL56_17480	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AVL56_17495	COG0543	2 iron, 2 sulfur cluster binding
AVL56_17500	COG2234	aminopeptidase activity
AVL56_17520	COG1271	oxidase subunit
AVL56_17525	COG1294	oxidase, subunit
AVL56_17530	COG0840	transmembrane signaling receptor activity
AVL56_17535	COG1522	sequence-specific DNA binding
AVL56_17550	COG1278	Cold shock
AVL56_17555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AVL56_17575	COG0339	signal peptide processing
AVL56_17580	COG2201	protein-glutamate methylesterase activity
AVL56_17590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVL56_17590	COG4191	Histidine kinase
AVL56_17600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVL56_17605	COG0243	molybdopterin cofactor binding
AVL56_17610	COG4946	Tricorn protease homolog
AVL56_17610	COG0793	Belongs to the peptidase S41A family
AVL56_17650	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AVL56_17655	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AVL56_17660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AVL56_17675	COG0281	malic enzyme
AVL56_17680	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AVL56_17685	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AVL56_17715	COG0456	acetyltransferase
AVL56_17725	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AVL56_17730	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AVL56_17735	COG2177	Part of the ABC transporter FtsEX involved in
AVL56_17740	COG2884	Cell division ATP-binding protein ftsE
AVL56_17745	COG0552	protein localization to endoplasmic reticulum
AVL56_17750	COG0742	ribosomal rna small subunit methyltransferase
AVL56_17760	COG2095	MarC family integral membrane protein
AVL56_17780	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AVL56_17785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVL56_17795	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AVL56_17810	COG0076	glutamate decarboxylase activity
AVL56_17815	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AVL56_17825	COG0842	Transport permease protein
AVL56_17830	COG1131	(ABC) transporter
AVL56_17835	COG0745	RESPONSE REGULATOR receiver
AVL56_17840	COG2205	protein histidine kinase activity
AVL56_17845	COG4774	siderophore transport
AVL56_17865	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AVL56_17870	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AVL56_17880	COG0535	radical SAM domain protein
AVL56_17895	COG1253	flavin adenine dinucleotide binding
AVL56_17900	COG0701	Predicted permease
AVL56_17905	COG1966	Carbon starvation protein
AVL56_17955	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AVL56_17960	COG0049	tRNA binding
AVL56_17965	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AVL56_17970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AVL56_17975	COG0085	RNA polymerase activity
AVL56_17980	COG0222	ribosome binding
AVL56_17985	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AVL56_17990	COG0081	regulation of translation
AVL56_17995	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AVL56_18000	COG0250	Participates in transcription elongation, termination and antitermination
AVL56_18005	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVL56_18015	COG1132	(ABC) transporter
AVL56_18020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVL56_18025	COG3590	peptidase
AVL56_18035	COG0513	Belongs to the DEAD box helicase family
AVL56_18040	COG0418	dihydroorotase activity
AVL56_18050	COG3040	lipid binding
AVL56_18055	COG4989	oxidoreductase activity
AVL56_18060	COG0346	lactoylglutathione lyase activity
AVL56_18075	COG0302	gtp cyclohydrolase
AVL56_18095	COG2957	Belongs to the agmatine deiminase family
AVL56_18100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVL56_18115	COG3306	glycosyltransferase involved in LPS biosynthesis
AVL56_18120	COG1201	RNA secondary structure unwinding
AVL56_18130	COG1793	dna ligase
AVL56_18140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVL56_18155	COG0625	glutathione transferase activity
AVL56_18170	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AVL56_18175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AVL56_18185	COG1012	belongs to the aldehyde dehydrogenase family
AVL56_18200	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AVL56_18205	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AVL56_18210	COG0330	HflC and HflK could
AVL56_18215	COG0330	HflC and HflK could
AVL56_18220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AVL56_18225	COG1923	regulation of RNA biosynthetic process
AVL56_18230	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AVL56_18245	COG0802	atpase or kinase
AVL56_18250	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AVL56_18250	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AVL56_18255	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AVL56_18265	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AVL56_18270	COG2816	NAD+ diphosphatase activity
AVL56_18275	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AVL56_18280	COG0735	belongs to the Fur family
AVL56_18290	COG0432	Pfam Uncharacterised protein family UPF0047
AVL56_18300	COG0305	Participates in initiation and elongation during chromosome replication
AVL56_18325	COG2258	MOSC domain
AVL56_18355	COG5002	protein histidine kinase activity
AVL56_18365	COG0840	transmembrane signaling receptor activity
AVL56_18370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVL56_18370	COG4191	Histidine kinase
AVL56_18380	COG1609	Transcriptional regulator
AVL56_18385	COG2211	Major facilitator Superfamily
AVL56_18390	COG2723	6-phospho-beta-galactosidase activity
AVL56_18400	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AVL56_18405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVL56_18410	COG4558	Periplasmic binding protein
AVL56_18420	COG4206	TonB-dependent receptor
AVL56_18430	COG1472	Belongs to the glycosyl hydrolase 3 family
AVL56_18445	COG2855	membrane
AVL56_18450	COG2175	clavaminate synthase activity
AVL56_18455	COG0656	L-ascorbic acid biosynthetic process
AVL56_18475	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVL56_18480	COG1230	cation diffusion facilitator family transporter
AVL56_18515	COG4771	TonB-dependent receptor
AVL56_18520	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AVL56_18525	COG4988	ABC transporter
AVL56_18535	COG1294	oxidase, subunit
AVL56_18550	COG2204	response regulator
AVL56_18585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AVL56_18615	COG4319	ketosteroid isomerase
AVL56_18655	COG3237	CsbD-like
AVL56_18700	COG2267	carboxylic ester hydrolase activity
AVL56_18725	COG3038	cytochrome b561
AVL56_18730	COG2353	YceI-like domain
AVL56_18735	COG1252	NADH dehydrogenase
AVL56_18765	COG2130	NADP-dependent
AVL56_18770	COG2203	Gaf domain
AVL56_18770	COG3706	GGDEF domain
AVL56_18770	COG4251	negative regulation of phosphorylation
AVL56_18770	COG5001	Diguanylate cyclase
AVL56_18790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVL56_18800	COG4181	ATPase activity
AVL56_18820	COG0523	cobalamin synthesis protein
AVL56_18835	COG4771	TonB-dependent receptor
AVL56_18840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AVL56_18865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVL56_18870	COG1349	DNA-binding transcription factor activity
AVL56_18885	COG0697	spore germination
AVL56_18890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVL56_18895	COG4977	sequence-specific DNA binding
AVL56_18915	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AVL56_18920	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AVL56_18925	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AVL56_18935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVL56_18945	COG0523	cobalamin synthesis protein
AVL56_18975	COG4232	protein-disulfide reductase activity
AVL56_18980	COG0739	heme binding
AVL56_18985	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AVL56_18990	COG0511	ligase activity, forming carbon-carbon bonds
AVL56_18995	COG0439	Biotin carboxylase
AVL56_19015	COG2176	DNA-directed DNA polymerase activity
AVL56_19035	COG0154	amidase activity
AVL56_19050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVL56_19055	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AVL56_19070	COG0151	Belongs to the GarS family
AVL56_19080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVL56_19090	COG3954	Phosphoribulokinase
AVL56_19095	COG2233	PERMEase
AVL56_19115	COG0745	RESPONSE REGULATOR receiver
AVL56_19135	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AVL56_19145	COG3031	protein transport across the cell outer membrane
AVL56_19155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVL56_19160	COG1459	type II secretion system
AVL56_19165	COG2165	general secretion pathway protein
AVL56_19175	COG2165	general secretion pathway protein
AVL56_19180	COG4795	General secretion pathway protein
AVL56_19195	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AVL56_19205	COG1234	tRNA 3'-trailer cleavage
AVL56_19210	COG1012	belongs to the aldehyde dehydrogenase family
AVL56_19220	COG1011	Hydrolase
AVL56_19225	COG0494	nUDIX hydrolase
AVL56_19230	COG1218	3'(2'),5'-bisphosphate nucleotidase
AVL56_19245	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AVL56_19255	COG3089	Belongs to the UPF0270 family
AVL56_19260	COG0429	hydrolase of the alpha beta-hydrolase fold
AVL56_19270	COG0488	(ABC) transporter
AVL56_19295	COG0545	Peptidyl-prolyl cis-trans isomerase
AVL56_19305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVL56_19310	COG2183	response to ionizing radiation
AVL56_19325	COG0596	Alpha beta hydrolase
AVL56_19330	COG1040	competence protein
AVL56_19350	COG1794	racemase activity, acting on amino acids and derivatives
AVL56_19365	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AVL56_19370	COG0534	Mate efflux family protein
AVL56_19385	COG1999	signal sequence binding
AVL56_19390	COG0109	protoheme IX farnesyltransferase activity
AVL56_19395	COG1612	heme a metabolic process
AVL56_19420	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AVL56_19425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVL56_19430	COG1565	acr, cog1565
AVL56_19430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AVL56_19440	COG4974	Belongs to the 'phage' integrase family
AVL56_19475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVL56_19485	COG0786	glutamate:sodium symporter activity
AVL56_19545	COG0129	dihydroxy-acid dehydratase activity
AVL56_19550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVL56_19560	COG0606	chelatase, subunit chli
AVL56_19565	COG0583	DNA-binding transcription factor activity
AVL56_19575	COG2814	Major facilitator Superfamily
AVL56_19585	COG0729	surface antigen
AVL56_19590	COG2911	Protein conserved in bacteria
AVL56_19615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVL56_19625	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AVL56_19645	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AVL56_19695	COG0425	Belongs to the sulfur carrier protein TusA family
AVL56_19710	COG1561	YicC-like family, N-terminal region
AVL56_19745	COG2211	Major facilitator Superfamily
AVL56_19750	COG1609	Transcriptional regulator
AVL56_19765	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AVL56_19765	COG2199	diguanylate cyclase activity
AVL56_19795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AVL56_19815	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVL56_19820	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVL56_19840	COG1475	DNA binding
AVL56_19845	COG1192	Involved in chromosome partitioning
AVL56_19870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AVL56_19875	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AVL56_19885	COG0706	membrane insertase activity
AVL56_19890	COG0594	ribonuclease P activity
AVL56_19895	COG0230	Belongs to the bacterial ribosomal protein bL34 family