locus-tag	class	description
EP12_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
EP12_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
EP12_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
EP12_00030	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
EP12_00035	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
EP12_00040	ENOG4108R3E	Dna-3-methyladenine glycosylase i
EP12_00050	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
EP12_00060	ENOG4106RE7	Cytochrome
EP12_00065	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
EP12_00070	ENOG4105C2M	dna polymerase I
EP12_00075	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
EP12_00080	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
EP12_00090	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EP12_00095	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
EP12_00100	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EP12_00105	ENOG4108WZM	domain protein
EP12_00110	ENOG4105C79	DNA protecting protein DprA
EP12_00115	ENOG4108RPN	Protein smg homolog
EP12_00125	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EP12_00130	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
EP12_00145	ENOG4105E2X	shikimate dehydrogenase
EP12_00150	ENOG4108Z0R	Transferase
EP12_00205	ENOG4105C0B	DNA polymerase III (alpha subunit)
EP12_00235	ENOG4105IIU	Aminopeptidase
EP12_00240	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
EP12_00260	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
EP12_00265	ENOG4105W5Q	DNA repair protein (RadC
EP12_00285	ENOG4105E3R	(LipO)protein
EP12_00290	ENOG4105KDC	50s ribosomal protein l28
EP12_00295	ENOG4105W0E	50S ribosomal protein L33
EP12_00305	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
EP12_00320	ENOG4105DKP	glycosyl transferase, family 9
EP12_00335	ENOG4105BZU	Histidine kinase
EP12_00340	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EP12_00345	ENOG4105CPQ	Dehydrogenase
EP12_00350	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
EP12_00355	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
EP12_00365	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
EP12_00370	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
EP12_00375	ENOG4105W0Z	cytoplasmic protein
EP12_00380	ENOG4105C4R	Atp-dependent dna helicase
EP12_00385	ENOG4105BZU	Histidine kinase
EP12_00390	ENOG4105MPD	Cytochrome
EP12_00440	ENOG4105CJ1	ABC, transporter
EP12_00445	ENOG4105CMI	transporter
EP12_00450	ENOG4105CNM	Receptor
EP12_00455	ENOG4107RNH	Outer membrane receptor FepA
EP12_00460	ENOG4105C1G	acyl-Coa dehydrogenase
EP12_00465	ENOG41064T2	transcriptional regulator, lysR family
EP12_00475	ENOG4105CM6	amino acid regulated cytosolic protein
EP12_00490	ENOG4105D41	biosynthesis protein thiH
EP12_00495	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
EP12_00505	ENOG4105D06	uba thif-type nad fad binding protein
EP12_00510	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
EP12_00515	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
EP12_00535	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
EP12_00555	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
EP12_00570	ENOG4108R86	Transcriptional regulator
EP12_00575	ENOG4105EVZ	LysR family transcriptional regulator
EP12_00580	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EP12_00585	ENOG4105C26	Dehydrogenase
EP12_00595	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
EP12_00600	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
EP12_00615	ENOG4105ECF	c-methyltransferase
EP12_00620	ENOG41076E6	Uroporphyrinogen-III Synthase
EP12_00625	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
EP12_00630	ENOG4105BZU	Histidine kinase
EP12_00640	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
EP12_00645	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
EP12_00650	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EP12_00655	ENOG4105KME	endoribonuclease L-psp
EP12_00660	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
EP12_00665	ENOG4105CB5	ATP-dependent DNA helicase recG
EP12_00695	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
EP12_00700	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EP12_00710	ENOG4105CBX	hi0933 family
EP12_00735	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EP12_00740	ENOG4107RDJ	Sulfotransferase
EP12_00745	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EP12_00750	ENOG4105CYW	agmatinase
EP12_00770	ENOG4107W25	arginase agmatinase formiminoglutamase
EP12_00775	ENOG4105BZU	Histidine kinase
EP12_00785	ENOG4105C32	Amino acid ABC transporter (Permease)
EP12_00790	ENOG4105CNN	ABC, transporter
EP12_00795	ENOG4105C0Z	ABC transporter
EP12_00800	ENOG4108IV0	ABC, transporter
EP12_00805	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
EP12_00810	ENOG4108YZ9	Urea amidohydrolase subunit gamma
EP12_00815	ENOG4105KI2	Urea amidohydrolase subunit beta
EP12_00820	ENOG4105CQM	Urea amidohydrolase subunit alpha
EP12_00825	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
EP12_00830	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
EP12_00835	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
EP12_00850	ENOG4105BZU	Histidine kinase
EP12_00860	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
EP12_00880	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
EP12_00885	ENOG4105BZS	acriflavin resistance protein
EP12_00895	ENOG4105CYC	Transferase
EP12_00930	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
EP12_00935	ENOG4105BZU	Histidine kinase
EP12_00950	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EP12_00955	ENOG4108VUY	thioesterase Superfamily protein
EP12_00960	ENOG4105CJW	magnesium transporter
EP12_00965	ENOG4105FR1	rard protein
EP12_00970	ENOG4105BZU	Histidine kinase
EP12_00975	ENOG4105C4R	Atp-dependent dna helicase
EP12_00980	ENOG4105D7W	serine acetyltransferase
EP12_00985	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
EP12_00990	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EP12_01005	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
EP12_01025	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
EP12_01035	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
EP12_01040	ENOG4105DFU	Cell wall formation (By similarity)
EP12_01045	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EP12_01050	ENOG4105F0N	pyrophosphate phospho-hydrolase
EP12_01075	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
EP12_01080	ENOG4107RDB	Major Facilitator
EP12_01085	ENOG4107VXZ	Hydrolase
EP12_01105	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
EP12_01110	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
EP12_01115	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
EP12_01150	ENOG4108J1Q	
EP12_01185	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
EP12_01215	ENOG4105QV4	Tryptophan halogenase
EP12_01220	ENOG4107RUZ	Sss sodium solute transporter superfamily
EP12_01230	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EP12_01255	ENOG4105DFF	Rod shape-determining protein mreb
EP12_01260	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
EP12_01265	ENOG4105VQ7	Rod shape-determining protein MreD
EP12_01270	ENOG4108Z03	MAF-like protein
EP12_01275	ENOG4105C03	ribonuclease
EP12_01290	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
EP12_01295	ENOG4105N42	UPF0307 protein
EP12_01300	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
EP12_01315	ENOG41065U4	response regulator
EP12_01320	ENOG4105BZU	Histidine kinase
EP12_01335	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
EP12_01340	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
EP12_01345	ENOG4105CEN	a g-specific adenine glycosylase
EP12_01350	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
EP12_01375	ENOG4105DZR	Type I site-specific deoxyribonuclease
EP12_01395	ENOG4105CVR	type I restriction-modification system
EP12_01445	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EP12_01490	ENOG4105PGM	cation diffusion facilitator family transporter
EP12_01505	ENOG4105DIJ	Phosphoethanolamine transferase
EP12_01510	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
EP12_01520	ENOG4105CKK	Glycosyl transferase, family 2
EP12_01580	ENOG4105C59	p-type ATPase
EP12_01620	ENOG4107R7I	amino acid
EP12_01630	ENOG4105E3B	Multicopper oxidase
EP12_01720	ENOG410804D	Sensor Signal Transduction Histidine Kinase
EP12_01735	ENOG4105C6X	Major Facilitator
EP12_01740	ENOG4105C8Q	Methyl-accepting chemotaxis
EP12_01745	ENOG4108VYJ	response regulator receiver protein
EP12_01750	ENOG4105CBS	Chea signal transduction histidine kinase
EP12_01755	ENOG4108V3W	Chemotaxis protein, CheW
EP12_01760	ENOG4107SDU	Methyl-accepting chemotaxis
EP12_01765	ENOG4105BZU	Histidine kinase
EP12_01770	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
EP12_01775	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
EP12_01805	ENOG4105KSC	Transcriptional regulator, TraR DksA family
EP12_01865	ENOG4107QM2	Aldo Keto reductase
EP12_01870	ENOG4105QNF	Outer membrane lipoprotein
EP12_01885	ENOG4105C1J	atp-dependent rna helicase
EP12_01895	ENOG4105C9K	Endothelin-converting enzyme 1
EP12_01900	ENOG4105JSC	dimethylmenaquinone methyltransferase
EP12_01905	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EP12_01910	ENOG4105D58	Diguanylate phosphodiesterase
EP12_01915	ENOG4105BZ1	(ABC) transporter
EP12_01925	ENOG4105PM1	preprotein translocase subunit SecE
EP12_01930	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
EP12_01945	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EP12_01950	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
EP12_01955	ENOG4108VZM	50s ribosomal protein L10
EP12_01960	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
EP12_01965	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EP12_01970	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EP12_01975	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
EP12_01980	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
EP12_02025	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EP12_02030	ENOG4107QM5	aconitate hydratase
EP12_02035	ENOG4107QHF	type ii secretion system protein e
EP12_02040	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
EP12_02045	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
EP12_02050	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
EP12_02055	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
EP12_02060	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EP12_02065	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
EP12_02070	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
EP12_02075	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
EP12_02080	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
EP12_02085	ENOG41083MP	50s ribosomal protein l29
EP12_02090	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
EP12_02095	ENOG4107RJ7	Glycosyl transferase (Group 1
EP12_02100	ENOG4105D16	lipopolysaccharide heptosyltransferase i
EP12_02120	ENOG4105C8Q	Methyl-accepting chemotaxis
EP12_02125	ENOG4105DGW	oligopeptidase A
EP12_02170	ENOG4105BZ4	penicillin-binding protein
EP12_02190	ENOG4108K2B	transcriptional regulator
EP12_02205	ENOG4108YZA	Nitrogen regulatory protein pii
EP12_02220	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EP12_02225	ENOG4105EZR	dyp-type peroxidase family protein
EP12_02230	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
EP12_02260	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EP12_02270	ENOG4105BZU	Histidine kinase
EP12_02290	ENOG4105C8Y	Acetylornithine aminotransferase
EP12_02300	ENOG4105DDQ	anthranilate synthase
EP12_02305	ENOG4105C31	Tryptophanyl-tRNA synthetase
EP12_02310	ENOG4105DJV	ribulose-phosphate 3-epimerase
EP12_02340	ENOG4105D49	3-dehydroquinate synthase
EP12_02345	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
EP12_02350	ENOG4105E4G	Type IV pilus
EP12_02375	ENOG4108JQC	penicillin-binding protein 1A
EP12_02380	ENOG4107R1I	NAD-dependent malic enzyme
EP12_02390	ENOG4105CYM	Glutathione S-transferase
EP12_02395	ENOG4105CH6	catalase
EP12_02415	ENOG4105BZU	Histidine kinase
EP12_02420	ENOG4107QZM	n-acetylglutamate synthase
EP12_02425	ENOG4105CH7	arginosuccinase
EP12_02430	ENOG4105CDH	Citrulline--aspartate ligase
EP12_02440	ENOG4105CAS	nag kinase
EP12_02445	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
EP12_02450	ENOG4108Z5K	methylglyoxal synthase
EP12_02475	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EP12_02485	ENOG4108EUD	Lysophospholipase
EP12_02490	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
EP12_02500	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
EP12_02505	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
EP12_02515	ENOG4107YZP	Rhodanese domain protein
EP12_02520	ENOG41063SB	peptidase
EP12_02550	ENOG4105DJ4	phosphatidylserine decarboxylase
EP12_02555	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
EP12_02560	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
EP12_02595	ENOG4105C7K	acetolactate synthase
EP12_02600	ENOG4108ZP8	Acetolactate synthase small subunit
EP12_02610	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
EP12_02615	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
EP12_02635	ENOG4105BZU	Histidine kinase
EP12_02640	ENOG4105D52	delta-aminolevulinic acid dehydratase
EP12_02645	ENOG4105C9X	ppx gppa phosphatase
EP12_02650	ENOG4105C1J	atp-dependent rna helicase
EP12_02655	ENOG4105K63	Thioredoxin
EP12_02670	ENOG4105CH2	amidohydrolase
EP12_02675	ENOG4105BZU	Histidine kinase
EP12_02680	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
EP12_02685	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
EP12_02690	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
EP12_02725	ENOG4107QR8	Thioredoxin
EP12_02730	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
EP12_02735	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
EP12_02740	ENOG4105C26	Dehydrogenase
EP12_02745	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EP12_02750	ENOG4107S6Z	Na H antiporter
EP12_02765	ENOG4105EHZ	conserved protein UCP016719
EP12_02775	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EP12_02810	ENOG4105K3M	)-transporter
EP12_02875	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EP12_02920	ENOG4105CI2	imidazolone-5-propionate hydrolase
EP12_02955	ENOG4105CHU	acetyl-coa acetyltransferase
EP12_02960	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EP12_02975	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
EP12_02985	ENOG4105EAH	synthase
EP12_02990	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
EP12_02995	ENOG4105K46	50S ribosomal protein l27
EP12_03000	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EP12_03010	ENOG4108VEQ	Superoxide dismutase
EP12_03035	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EP12_03040	ENOG4108K5P	(LipO)protein
EP12_03045	ENOG4108UM1	dedA family
EP12_03050	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
EP12_03055	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
EP12_03060	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
EP12_03070	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
EP12_03075	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
EP12_03085	ENOG4105C8Q	Methyl-accepting chemotaxis
EP12_03095	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
EP12_03110	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EP12_03115	ENOG4105F3H	Histidine kinase
EP12_03140	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
EP12_03145	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
EP12_03150	ENOG4105HF0	Membrane
EP12_03155	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
EP12_03175	ENOG4105BZU	Histidine kinase
EP12_03195	ENOG4105D3G	Pseudouridine synthase
EP12_03220	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EP12_03225	ENOG4105C1J	atp-dependent rna helicase
EP12_03245	ENOG4105DFG	type I secretion outer membrane protein
EP12_03250	ENOG41087AY	ADP-Ribose pyrophosphatase
EP12_03255	ENOG4108SX3	cytoplasmic protein
EP12_03265	ENOG4105IPS	esterase
EP12_03275	ENOG4105BZU	Histidine kinase
EP12_03280	ENOG4105BZU	Histidine kinase
EP12_03285	ENOG4107VXZ	Hydrolase
EP12_03305	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
EP12_03310	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
EP12_03320	ENOG4105UGU	tonB-dependent Receptor
EP12_03330	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
EP12_03335	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
EP12_03345	ENOG4105M85	Bola protein
EP12_03365	ENOG4105CHH	sulfate transporter
EP12_03370	ENOG4107QZF	nitrite reductase NADPH large subunit
EP12_03375	ENOG4105WZK	nitrite reductase NADPH small subunit
EP12_03385	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EP12_03390	ENOG4107QYG	anthranilate phosphoribosyltransferase
EP12_03410	ENOG4105DG7	nitrate ABC transporter
EP12_03415	ENOG4105D7T	ABC transporter
EP12_03425	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
EP12_03435	ENOG4108Z33	Thiol disulfide Interchange Protein
EP12_03440	ENOG4105E27	serine threonine protein kinase
EP12_03445	ENOG4105C58	cytochrome c oxidase accessory protein ccog
EP12_03465	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
EP12_03475	ENOG4105CXK	mandelate racemase muconate lactonizing
EP12_03480	ENOG4105MP9	class II Aldolase
EP12_03490	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
EP12_03495	ENOG4105BZS	acriflavin resistance protein
EP12_03525	ENOG4105C8Q	Methyl-accepting chemotaxis
EP12_03530	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EP12_03535	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
EP12_03545	ENOG4105VCC	30S ribosomal protein S21
EP12_03550	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EP12_03555	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
EP12_03570	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
EP12_03575	ENOG4107YU2	histidine triad (hIT) protein
EP12_03590	ENOG4105DKK	Benzoate
EP12_03595	ENOG4108JCI	Transcriptional regulator
EP12_03605	ENOG4105BZU	Histidine kinase
EP12_03610	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EP12_03615	ENOG4105BZU	Histidine kinase
EP12_03655	ENOG4109015	Biopolymer transport protein exbD tolR
EP12_03670	ENOG41061N2	exported protein
EP12_03680	ENOG4105BZU	Histidine kinase
EP12_03685	ENOG4105CEY	Amp-dependent synthetase and ligase
EP12_03700	ENOG4107QIJ	Aconitate hydratase 2
EP12_03715	ENOG4107QIJ	Aconitate hydratase 2
EP12_03725	ENOG4105CFH	Aspartokinase
EP12_03730	ENOG4105C8Q	Methyl-accepting chemotaxis
EP12_03740	ENOG4105NWN	ApaG protein
EP12_03745	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EP12_03750	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
EP12_03755	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
EP12_03760	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
EP12_03770	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
EP12_03775	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EP12_03780	ENOG4105T95	Thiol disulfide interChange protein
EP12_03800	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
EP12_03805	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
EP12_03815	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EP12_03820	ENOG4105DXN	mazG family
EP12_03830	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
EP12_03835	ENOG4108UJD	30S ribosomal protein S9
EP12_03840	ENOG4108SF5	RNA Polymerase
EP12_03850	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EP12_03860	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EP12_03865	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EP12_03870	ENOG4105EIX	cytochrome c1
EP12_03875	ENOG4107MKT	Stringent starvation protein a
EP12_03880	ENOG4105KB2	stringent starvation protein b
EP12_03895	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EP12_03900	ENOG4105CJW	magnesium transporter
EP12_03905	ENOG41080Z8	PHOSPHOCARRIER protein
EP12_03910	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
EP12_03915	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
EP12_03920	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
EP12_03925	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EP12_03930	ENOG4108IUZ	ABC transporter
EP12_03945	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
EP12_03950	ENOG4105C2X	Arabinose 5-phosphate isomerase
EP12_03960	ENOG4105DHJ	ABC, transporter
EP12_03965	ENOG4105CY3	ABC transporter, permease
EP12_03970	ENOG4107PE3	Mammalian cell entry related domain protein
EP12_03975	ENOG4105E3I	toluene tolerance
EP12_03985	ENOG4105VFK	BolA family
EP12_03990	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
EP12_03995	ENOG4105C0H	protease
EP12_04005	ENOG4105C0H	protease
EP12_04020	ENOG4105D6Z	AFG1 family ATPase
EP12_04025	ENOG4105CDY	transcriptional regulatory protein
EP12_04075	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EP12_04085	ENOG4105BZU	Histidine kinase
EP12_04100	ENOG4108I6A	alcohol dehydrogenase
EP12_04120	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
EP12_04125	ENOG4105CV1	Transketolase (EC 2.2.1.1)
EP12_04130	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
EP12_04135	ENOG4105BZA	Phosphoglycerate kinase
EP12_04140	ENOG4105WYW	fructose-bisphosphate aldolase
EP12_04145	ENOG4105C9X	ppx gppa phosphatase
EP12_04160	ENOG4105C8U	phosphate abc transporter
EP12_04170	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
EP12_04180	ENOG4105CJ3	phosphate transporter
EP12_04185	ENOG4105Q9Y	Universal stress protein
EP12_04190	ENOG4105C5Q	Transcriptional regulator
EP12_04200	ENOG4108UT2	hemolysin iii
EP12_04205	ENOG4105K56	Transcriptional regulator
EP12_04210	ENOG4108ZHJ	Organic hydroperoxide resistance protein
EP12_04220	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
EP12_04225	ENOG4107SDU	Methyl-accepting chemotaxis
EP12_04235	ENOG4105EYH	Exonuclease
EP12_04240	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
EP12_04250	ENOG4105ENX	hydrolase
EP12_04255	ENOG4105CF7	AraC family transcriptional regulator
EP12_04260	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
EP12_04275	ENOG4105CYM	Glutathione S-transferase
EP12_04320	ENOG4105CE4	GlcNAc 6-P deacetylase
EP12_04370	ENOG4105KHC	sulfurtransferase
EP12_04375	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
EP12_04380	ENOG4106IUH	DTW domain containing protein
EP12_04430	ENOG41067MG	lrgb family
EP12_04460	ENOG4105CSA	Coproporphyrinogen iii oxidase
EP12_04465	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
EP12_04470	ENOG4105C1J	atp-dependent rna helicase
EP12_04475	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EP12_04495	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EP12_04500	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EP12_04505	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EP12_04510	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EP12_04525	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
EP12_04530	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
EP12_04545	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
EP12_04560	ENOG4108IUW	ABC transporter
EP12_04565	ENOG4108SDH	ABC, transporter
EP12_04580	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
EP12_04585	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
EP12_04590	ENOG41060IM	Heme exporter protein
EP12_04595	ENOG4105X3C	heme exporter protein
EP12_04600	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
EP12_04605	ENOG4105DA4	cytochrome c-type biogenesis protein
EP12_04610	ENOG4107QX9	Thiol disulfide interChange protein
EP12_04615	ENOG4108M1T	Cytochrome c-type biogenesis protein
EP12_04630	ENOG4105CMR	udp-glucose 4-epimerase
EP12_04660	ENOG4107V1M	polysaccharide export protein
EP12_04670	ENOG4105ESV	Glycosyl transferase, family 4
EP12_04685	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
EP12_04690	ENOG4105KQC	Competence protein
EP12_04695	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EP12_04710	ENOG4105EWT	decarboxylase family
EP12_04715	ENOG4105BZU	Histidine kinase
EP12_04720	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
EP12_04725	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
EP12_04745	ENOG4105CNA	YD repeat protein
EP12_04765	ENOG4108R8Z	these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression
EP12_04805	ENOG4105DR9	pseudouridine synthase
EP12_04810	ENOG4105QDK	Flavodoxin
EP12_04815	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
EP12_04820	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
EP12_04825	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
EP12_04830	ENOG4105CE9	30S ribosomal protein S2
EP12_04835	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
EP12_04840	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
EP12_04845	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
EP12_04850	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
EP12_04855	ENOG4105KNE	Phosphatidate cytidylyltransferase
EP12_04875	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
EP12_04880	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
EP12_04885	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EP12_04890	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EP12_04895	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EP12_04905	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
EP12_04915	ENOG4105BZU	Histidine kinase
EP12_04930	ENOG4108Z6B	deaminase
EP12_04935	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
EP12_04940	ENOG4108ETH	Formylglycinamide ribotide synthetase
EP12_04950	ENOG4108DG9	Smr protein MutS2
EP12_04985	ENOG4107R88	Chemotaxis protein (CheV)
EP12_04990	ENOG4105BZU	Histidine kinase
EP12_04995	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
EP12_05000	ENOG4108ZC9	flagellar basal-body rod protein flgc
EP12_05010	ENOG4105BZE	flagellar hook protein, FlgE
EP12_05015	ENOG4108KPB	Flagellar basal-body rod protein FlgF
EP12_05020	ENOG4105CGA	flagellar basal-body rod protein FlgG
EP12_05025	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
EP12_05035	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
EP12_05040	ENOG4105E1Q	flagellar hook-associated protein
EP12_05055	ENOG4105I03	Flagellin
EP12_05060	ENOG4105I03	Flagellin
EP12_05075	ENOG41063QE	flagellar protein FlaG
EP12_05085	ENOG4105MQ3	flagellar protein FliS
EP12_05095	ENOG4105C5E	polysaccharide biosynthesis protein
EP12_05100	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
EP12_05105	ENOG4105F0R	Cytidylyltransferase
EP12_05110	ENOG4105D2T	synthase
EP12_05130	ENOG4105CHR	reductase
EP12_05170	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
EP12_05185	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
EP12_05195	ENOG4105C5R	Aminotransferase
EP12_05205	ENOG4105KPE	licD family
EP12_05210	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
EP12_05245	ENOG4107R5Z	Oxidoreductase domain protein
EP12_05250	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
EP12_05255	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
EP12_05260	ENOG4105I03	Flagellin
EP12_05265	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EP12_05270	ENOG4105BZU	Histidine kinase
EP12_05275	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EP12_05280	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
EP12_05285	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
EP12_05290	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
EP12_05300	ENOG4108JIR	Flagellum-specific ATP synthase
EP12_05320	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
EP12_05325	ENOG4105DD5	Flagellar motor switch protein
EP12_05330	ENOG4105VTB	flagellar biosynthesis protein fliO
EP12_05335	ENOG4105CN7	Flagellar biosynthetic protein FliP
EP12_05345	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
EP12_05350	ENOG4105D00	flagellar biosynthetic protein flhB
EP12_05355	ENOG4105D7B	Flagellar biosynthesis protein flha
EP12_05360	ENOG4105FZW	flagellar biosynthesis regulator FlhF
EP12_05370	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EP12_05375	ENOG4108VYJ	response regulator receiver protein
EP12_05380	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
EP12_05385	ENOG4105CBS	Chea signal transduction histidine kinase
EP12_05390	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
EP12_05395	ENOG4107QJE	Chromosome Partitioning Protein
EP12_05405	ENOG4105YFD	chemotaxis, protein
EP12_05415	ENOG4105CVG	Homoserine O-transsuccinylase
EP12_05430	ENOG4105C8Q	Methyl-accepting chemotaxis
EP12_05435	ENOG4105NBK	UPF0345 protein
EP12_05440	ENOG4105DZ2	Transcriptional regulator
EP12_05445	ENOG4105C5Q	Transcriptional regulator
EP12_05450	ENOG4107B2H	carbonic anhydrase
EP12_05460	ENOG4105C9K	Endothelin-converting enzyme 1
EP12_05470	ENOG4108004	Modulates RecA activity (By similarity)
EP12_05475	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EP12_05480	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
EP12_05505	ENOG4107QSA	Oxaloacetate decarboxylase
EP12_05510	ENOG4105D9Q	decarboxylase (Beta subunit)
EP12_05520	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
EP12_05525	ENOG4108EU3	peptide transport system, permease
EP12_05530	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EP12_05535	ENOG4105DEF	Extracellular solute-binding protein, family 5
EP12_05540	ENOG4105E51	psp operon transcriptional activator
EP12_05545	ENOG41087YS	Phage shock protein A
EP12_05550	ENOG4105YYT	phage shock protein B
EP12_05560	ENOG4105MIR	Phenylalanine 4-monooxygenase
EP12_05575	ENOG4108RXX	maleylacetoacetate isomerase
EP12_05580	ENOG4108XM1	transcriptional regulator AsnC family
EP12_05595	ENOG4108KPZ	tonB-dependent Receptor
EP12_05635	ENOG410822N	TonB family
EP12_05650	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
EP12_05690	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
EP12_05715	ENOG4105CV8	reductase
EP12_05760	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
EP12_05785	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
EP12_05850	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
EP12_05885	ENOG4105D9M	gamma-glutamylcysteine synthetase
EP12_05900	ENOG4105C19	ABC transporter
EP12_05915	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EP12_05930	ENOG4108DG9	Smr protein MutS2
EP12_05935	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
EP12_05955	ENOG4105ED1	spovr family
EP12_05970	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EP12_05975	ENOG4105M2J	Glutaredoxin
EP12_06015	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
EP12_06020	ENOG4108UYE	Lactoylglutathione lyase
EP12_06025	ENOG4105VEQ	Cold shock protein
EP12_06035	ENOG4105BZU	Histidine kinase
EP12_06040	ENOG4108M3R	transcriptional activator CadC
EP12_06135	ENOG4105DZB	Electron transport complex
EP12_06140	ENOG4108UQQ	Electron transport complex
EP12_06145	ENOG4105D6A	Electron transport complex
EP12_06155	ENOG4108R3D	Electron transport complex
EP12_06160	ENOG4105DGN	Electron transport complex
EP12_06175	ENOG4107QJQ	Mate efflux family protein
EP12_06180	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
EP12_06200	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
EP12_06205	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
EP12_06215	ENOG4105CAQ	asparagine synthetase
EP12_06250	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
EP12_06255	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
EP12_06260	ENOG4105C11	sulfate adenylyltransferase), subunit 2
EP12_06265	ENOG4105CK7	Sodium proline symporter
EP12_06280	ENOG4105EMN	RNA polymerase sigma factor
EP12_06295	ENOG4107QVM	von Willebrand factor, type A
EP12_06315	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EP12_06320	ENOG4105CHU	acetyl-coa acetyltransferase
EP12_06325	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EP12_06355	ENOG4108BY2	phosphohistidine phosphatase
EP12_06365	ENOG4108JU6	CBS domain protein
EP12_06370	ENOG4106KVJ	cytochrome C assembly protein
EP12_06380	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EP12_06425	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
EP12_06430	ENOG4105BZ1	(ABC) transporter
EP12_06450	ENOG4105K5M	30s ribosomal protein S16
EP12_06455	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
EP12_06460	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
EP12_06465	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
EP12_06470	ENOG4105EN6	Membrane
EP12_06480	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EP12_06500	ENOG4108VYJ	response regulator receiver protein
EP12_06505	ENOG4108ZJT	translation initiation factor, Sui1
EP12_06535	ENOG4107WP9	Histidine kinase
EP12_06545	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EP12_06550	ENOG41081XQ	Conserved Protein
EP12_06555	ENOG4105C9M	aspartyl-trna synthetase
EP12_06560	ENOG4108TIT	dATP pyrophosphohydrolase
EP12_06565	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
EP12_06570	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
EP12_06575	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
EP12_06580	ENOG4107YD3	Thioesterase
EP12_06585	ENOG4105E02	MotA TolQ exbB proton channel
EP12_06590	ENOG4105M8F	Biopolymer transport protein exbD tolR
EP12_06605	ENOG4105KCK	Peptidoglycan-associated lipoprotein
EP12_06610	ENOG4105UFD	tol-pal system protein YbgF
EP12_06630	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
EP12_06730	ENOG4105Y5J	prophage protein
EP12_06740	ENOG4105EFV	Major head subunit
EP12_06775	ENOG4105QIB	mu-like prophage Flumu protein gp29
EP12_06780	ENOG4105CF2	Mu-like prophage FluMu protein GP28
EP12_06785	ENOG4108Z6H	mu-like prophage Flumu protein gp27
EP12_06925	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
EP12_06955	ENOG4107VXZ	Hydrolase
EP12_06970	ENOG4105BZU	Histidine kinase
EP12_06990	ENOG4105EMU	Dehydrogenase
EP12_07000	ENOG4105DS1	cytochrome b561
EP12_07005	ENOG4105HEI	LysR family (Transcriptional regulator
EP12_07045	ENOG4105BZU	Histidine kinase
EP12_07055	ENOG4105DY2	Paraquat-inducible protein b
EP12_07060	ENOG4105F1S	paraquat-inducible protein a
EP12_07085	ENOG41082AG	Plasmid maintenance system antidote protein
EP12_07105	ENOG4105C5S	asparaginyl-tRNA synthetase
EP12_07120	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EP12_07145	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
EP12_07160	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
EP12_07165	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
EP12_07170	ENOG4105KJF	protein tyrosine phosphatase
EP12_07175	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
EP12_07185	ENOG4105DA5	(ABC) transporter
EP12_07200	ENOG4108NEV	two component transcriptional regulator, LytTR family
EP12_07210	ENOG4108JJ7	ABC transporter
EP12_07215	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EP12_07280	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
EP12_07285	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
EP12_07305	ENOG4108UJV	acyl-CoA thioesterase i
EP12_07310	ENOG4108I0Y	(ABC) transporter
EP12_07320	ENOG4105ECP	epimerase
EP12_07325	ENOG4105KKP	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
EP12_07330	ENOG4105DSF	transport protein
EP12_07335	ENOG4105IFJ	Histidine kinase
EP12_07340	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EP12_07355	ENOG4105K9H	YciI-like protein
EP12_07360	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
EP12_07370	ENOG4105DK0	Indole-3-glycerol phosphate synthase
EP12_07385	ENOG4105CRQ	synthase (Component I)
EP12_07390	ENOG4105DB7	PHP domain protein
EP12_07395	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
EP12_07400	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
EP12_07405	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
EP12_07410	ENOG4105FE9	pseudouridine synthase
EP12_07415	ENOG4105CV8	reductase
EP12_07420	ENOG4108UW5	maltose o-acetyltransferase
EP12_07435	ENOG4106BRA	Membrane
EP12_07440	ENOG4105FQ6	thiopurine methyltransferase
EP12_07445	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
EP12_07460	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
EP12_07465	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
EP12_07510	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EP12_07515	ENOG4105CFG	Acts as a chaperone (By similarity)
EP12_07520	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EP12_07525	ENOG41085AF	Cytochrome
EP12_07530	ENOG4105BZU	Histidine kinase
EP12_07540	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
EP12_07545	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
EP12_07550	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
EP12_07555	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EP12_07570	ENOG4108ZNX	Heat shock protein
EP12_07575	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
EP12_07585	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
EP12_07590	ENOG4108JU5	Magnesium and cobalt efflux protein
EP12_07595	ENOG4105D3Q	Sugar transferase
EP12_07610	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
EP12_07615	ENOG4105C9A	Phoh family
EP12_07620	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EP12_07625	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
EP12_07655	ENOG4108S4H	thioesterase Superfamily protein
EP12_07660	ENOG4107XWI	flavin reductase domain protein, FMN-binding
EP12_07665	ENOG4105BZG	amino acid carrier protein
EP12_07730	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
EP12_07760	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
EP12_07765	ENOG4107KU2	Outer membrane lipoprotein LolB
EP12_07775	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
EP12_07780	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
EP12_07785	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EP12_07790	ENOG4108YY7	Invasion gene expression up-regulator SirB
EP12_07795	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
EP12_07805	ENOG4105ETT	transcriptional Regulator, LysR family
EP12_07815	ENOG4105M08	Membrane
EP12_07820	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
EP12_07835	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
EP12_07840	ENOG4105D9P	serine threonine protein kinase
EP12_07850	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
EP12_07855	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
EP12_07860	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
EP12_07865	ENOG4105BZU	Histidine kinase
EP12_07870	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
EP12_07880	ENOG4105K8R	UPF0145 protein
EP12_07895	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EP12_07900	ENOG4105KUZ	arsenate reductase
EP12_08015	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
EP12_08025	ENOG4105BZU	Histidine kinase
EP12_08055	ENOG4105C7W	Xanthine dehydrogenase
EP12_08080	ENOG4105C7N	Xanthine uracil vitamin C permease
EP12_08095	ENOG4105BZU	Histidine kinase
EP12_08130	ENOG4105CNM	Receptor
EP12_08155	ENOG4105C5R	Aminotransferase
EP12_08160	ENOG4105HF0	Membrane
EP12_08165	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EP12_08200	ENOG4105CHR	reductase
EP12_08205	ENOG4105FGM	Fructosamine kinase
EP12_08210	ENOG4105C22	threonyL-tRNA synthetase
EP12_08215	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
EP12_08220	ENOG41082NX	50s ribosomal protein l35
EP12_08225	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
EP12_08230	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
EP12_08235	ENOG4105D3Q	Sugar transferase
EP12_08245	ENOG4105DAY	polysaccharide export protein
EP12_08255	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
EP12_08290	ENOG4107XU6	Glycosyl transferase (Group 1
EP12_08310	ENOG4105EXC	Acyl-transferase
EP12_08355	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
EP12_08360	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
EP12_08365	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EP12_08375	ENOG4108Z66	YbaK ebsC protein
EP12_08390	ENOG4108WBT	adenosyltransferase
EP12_08400	ENOG4108JA2	transcriptioN-repair coupling factor
EP12_08410	ENOG4105D60	lipoprotein releasing system transmembrane protein
EP12_08415	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
EP12_08425	ENOG4105CGK	Exodeoxyribonuclease III
EP12_08460	ENOG4105DNH	Major Facilitator
EP12_08470	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
EP12_08485	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
EP12_08500	ENOG4107QX3	carboxylase
EP12_08510	ENOG4108Z6Z	Transcriptional regulator
EP12_08515	ENOG4105CHU	acetyl-coa acetyltransferase
EP12_08530	ENOG4105CJB	Exodeoxyribonuclease I
EP12_08585	ENOG4105DR4	Methyltransferase
EP12_08590	ENOG4108JA1	polyketide synthase
EP12_08595	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EP12_08600	ENOG4108JDX	DNA polymerase iii, epsilon subunit
EP12_08635	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EP12_08640	ENOG4105D60	lipoprotein releasing system transmembrane protein
EP12_08655	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
EP12_08665	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
EP12_08670	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
EP12_08675	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
EP12_08680	ENOG4107YB6	acetyltransferase, (GNAT) family
EP12_08700	ENOG4105EI2	Pseudouridine synthase
EP12_08715	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
EP12_08720	ENOG4105VGS	50s ribosomal protein l32
EP12_08735	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
EP12_08740	ENOG4105CHR	reductase
EP12_08745	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
EP12_08750	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EP12_08760	ENOG4108J2P	Alpha beta hydrolase fold
EP12_08775	ENOG4105CSU	acyl-Coa dehydrogenase
EP12_08785	ENOG4105DKT	Transcriptional regulator
EP12_08790	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
EP12_08800	ENOG4105DEI	Mannitol dehydrogenase
EP12_08825	ENOG4105D8X	mechanosensitive ion channel
EP12_08830	ENOG4105D05	Receptor
EP12_08835	ENOG4105KZX	Pterin carbinolamine dehydratase
EP12_08855	ENOG4105BZU	Histidine kinase
EP12_08860	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EP12_08865	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
EP12_08870	ENOG4105CHV	Transcription elongation factor NusA
EP12_08875	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
EP12_08880	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
EP12_08885	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EP12_08890	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
EP12_08910	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
EP12_08940	ENOG4105D3R	alkyl hydroperoxide reductase
EP12_08980	ENOG4105CCT	upf0313 protein
EP12_08995	ENOG4105D05	Receptor
EP12_09000	ENOG4107QN2	dihydrolipoyl dehydrogenase
EP12_09010	ENOG4105VNH	ABC transporter solute-binding protein
EP12_09020	ENOG4108VGW	abc transporter atp-binding protein
EP12_09025	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
EP12_09035	ENOG4108TPP	exopolysaccharide synthesis
EP12_09040	ENOG4105EE1	crotonyl-CoA reductase
EP12_09075	ENOG4108N3W	hemolysin secretion protein
EP12_09095	ENOG4105CJ1	ABC, transporter
EP12_09120	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
EP12_09125	ENOG4108Z1B	Cyclase dehydrase
EP12_09130	ENOG4105VDB	UPF0125 protein
EP12_09140	ENOG4105C94	Transporter
EP12_09150	ENOG4107RDJ	Sulfotransferase
EP12_09155	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
EP12_09180	ENOG4105CQB	FAD linked oxidase domain protein
EP12_09190	ENOG4105EZE	Cupin 4 family protein
EP12_09200	ENOG4107QTF	adenylosuccinate lyase
EP12_09205	ENOG41075W9	High frequency lysogenization protein HflD homolog
EP12_09210	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
EP12_09215	ENOG4108R99	pseudouridine synthase
EP12_09220	ENOG4105E9K	Isocitrate dehydrogenase
EP12_09225	ENOG4105VEQ	Cold shock protein
EP12_09230	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
EP12_09235	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EP12_09240	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
EP12_09245	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
EP12_09250	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
EP12_09255	ENOG4105C3M	thioredoxin reductase
EP12_09265	ENOG4105GPY	SprT protein
EP12_09270	ENOG4105D07	Signal peptide peptidase, SppA
EP12_09280	ENOG41069NU	Nitroreductase
EP12_09290	ENOG4105HDK	L-asparaginase
EP12_09295	ENOG4105BZU	Histidine kinase
EP12_09300	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
EP12_09305	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EP12_09310	ENOG4108Z43	UPF0250 protein
EP12_09315	ENOG4105DZ1	carboxypeptidase
EP12_09320	ENOG4105K6T	rare lipoprotein A
EP12_09325	ENOG4105CNI	cell division protein FtsW
EP12_09330	ENOG4105CJN	penicillin-binding protein
EP12_09335	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
EP12_09340	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
EP12_09345	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
EP12_09350	ENOG4105DJF	DNA polymerase III, delta' subunit
EP12_09355	ENOG4108U2H	Rare lipoprotein B
EP12_09360	ENOG4105C8T	Leucyl-tRNA synthetase
EP12_09365	ENOG4105DAN	ATP-dependent protease
EP12_09375	ENOG4105HBR	Rna-binding protein
EP12_09380	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
EP12_09385	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EP12_09390	ENOG4105EEI	dihydropteroate synthase
EP12_09395	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
EP12_09400	ENOG4105CP7	Triose-phosphate isomerase
EP12_09430	ENOG4105D82	Glutamate dehydrogenase
EP12_09435	ENOG4107TE5	Lipid kinase
EP12_09445	ENOG4105CHR	reductase
EP12_09460	ENOG4105CK7	Sodium proline symporter
EP12_09470	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
EP12_09490	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EP12_09515	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
EP12_09530	ENOG4105EXN	Sulfate transport protein CysZ
EP12_09535	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
EP12_09540	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
EP12_09545	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
EP12_09560	ENOG4105BZ1	(ABC) transporter
EP12_09570	ENOG4105W49	UPF0434 protein
EP12_09575	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
EP12_09585	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
EP12_09685	ENOG4105CUZ	uba thif-type nad fad binding protein
EP12_09705	ENOG4105BZN	citrate synthase
EP12_09710	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
EP12_09715	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
EP12_09720	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
EP12_09725	ENOG4105E33	succinate dehydrogenase
EP12_09730	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
EP12_09735	ENOG4105C7S	Dehydrogenase
EP12_09740	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
EP12_09745	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
EP12_09790	ENOG4108IUK	alpha amylase, catalytic
EP12_09810	ENOG4105CX6	glutaminyL-tRNA synthetase
EP12_09815	ENOG4105UBK	short-chain dehydrogenase reductase
EP12_09820	ENOG4108M0H	Extracellular lipase
EP12_09825	ENOG4107SQI	penicillin amidase
EP12_09830	ENOG4105ERU	peptidase
EP12_09845	ENOG4106371	Methyltransferase
EP12_09855	ENOG4108V06	Glutathione peroxidase
EP12_09860	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EP12_09870	ENOG4105C26	Dehydrogenase
EP12_09875	ENOG4105C1G	acyl-Coa dehydrogenase
EP12_09885	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EP12_09890	ENOG4105DHI	Methyltransferase
EP12_09895	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
EP12_09900	ENOG4105E68	Sulfatase
EP12_09905	ENOG4105PAN	UPF0352 protein
EP12_09910	ENOG4106V8H	Nucleoid-associated protein
EP12_09940	ENOG4108HRK	Histidine kinase
EP12_09945	ENOG4108NEV	two component transcriptional regulator, LytTR family
EP12_09950	ENOG4105CTQ	phosphohexokinase
EP12_09980	ENOG4105DZR	Type I site-specific deoxyribonuclease
EP12_10005	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EP12_10010	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
EP12_10030	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
EP12_10065	ENOG4105BZU	Histidine kinase
EP12_10085	ENOG4105FE9	pseudouridine synthase
EP12_10095	ENOG4105BZU	Histidine kinase
EP12_10100	ENOG4105C1J	atp-dependent rna helicase
EP12_10110	ENOG4105D6N	CoA-transferase, subunit a
EP12_10140	ENOG4107R11	Transcriptional regulator
EP12_10145	ENOG4105EJQ	L-serine dehydratase
EP12_10155	ENOG4105CRQ	synthase (Component I)
EP12_10165	ENOG4105CGY	Dna recombination protein
EP12_10170	ENOG4105BZU	Histidine kinase
EP12_10190	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
EP12_10195	ENOG4107RUY	(E1 component), alpha subunit
EP12_10200	ENOG4105CPP	Dehydrogenase, E1 component
EP12_10210	ENOG4105D6S	protein involved in catabolism of external DNA
EP12_10220	ENOG4105C29	acyl-CoA thioesterase
EP12_10225	ENOG4108Z0R	Transferase
EP12_10230	ENOG4105C5R	Aminotransferase
EP12_10240	ENOG4108ZGC	gaf domain protein
EP12_10250	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
EP12_10255	ENOG4105CN1	protease
EP12_10260	ENOG4105C8J	)-transporter
EP12_10315	ENOG4108IJF	Heavy metal efflux pump, CzcA
EP12_10360	ENOG4105CHR	reductase
EP12_10380	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
EP12_10395	ENOG4107JPU	
EP12_10405	ENOG4105C45	hydrogenase expression formation protein (HypE)
EP12_10415	ENOG4105C59	p-type ATPase
EP12_10475	ENOG4105VR0	copper resistance
EP12_10480	ENOG4105E3B	Multicopper oxidase
EP12_10505	ENOG41063TF	transcriptional regulator (AraC
EP12_10510	ENOG4105W1Y	Transcriptional regulator
EP12_10535	ENOG4105PGM	cation diffusion facilitator family transporter
EP12_10560	ENOG4105GAV	receptor
EP12_10680	ENOG4105GR3	Histidine kinase
EP12_10685	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EP12_10695	ENOG4105D25	secreted protein
EP12_10715	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
EP12_10720	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
EP12_10730	ENOG4105C5H	ABC transporter
EP12_10740	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
EP12_10745	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
EP12_10755	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
EP12_10765	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
EP12_10770	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
EP12_10790	ENOG41080IJ	Diacylglycerol kinase
EP12_10795	ENOG41081QV	Universal stress protein
EP12_10815	ENOG4108UQY	Iron-storage protein
EP12_10830	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
EP12_10845	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
EP12_10870	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
EP12_10875	ENOG4105Q9Y	Universal stress protein
EP12_10885	ENOG4105D78	K07001 NTE family protein
EP12_10910	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EP12_10915	ENOG4105KHC	sulfurtransferase
EP12_10920	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
EP12_10925	ENOG4106IUH	DTW domain containing protein
EP12_11005	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
EP12_11010	ENOG4105WH1	Two component transcriptional regulator luxr family
EP12_11035	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
EP12_11040	ENOG4108VGI	doxx family
EP12_11045	ENOG4105CC0	LysR family Transcriptional regulator
EP12_11060	ENOG4108MN8	Membrane
EP12_11065	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
EP12_11080	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
EP12_11085	ENOG4108KP7	hydrolase
EP12_11090	ENOG4106B0W	Curli production assembly transport component CsgG
EP12_11100	ENOG4107Y60	(LipO)protein
EP12_11105	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
EP12_11110	ENOG4105WMR	Protein CrcB homolog
EP12_11115	ENOG4105D1H	recombination factor protein RarA
EP12_11120	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
EP12_11125	ENOG4105CNU	cell division protein FtsK
EP12_11130	ENOG4105EW9	transcriptional regulator AsnC family
EP12_11135	ENOG4105DCF	alanine dehydrogenase
EP12_11140	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
EP12_11145	ENOG4105CFV	Tetratricopeptide repeat protein
EP12_11160	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EP12_11165	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
EP12_11170	ENOG4105CAT	Cytidine monophosphate kinase
EP12_11175	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
EP12_11180	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
EP12_11200	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EP12_11205	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EP12_11210	ENOG4105XPH	Ferredoxin
EP12_11245	ENOG4105C8V	SAICAR synthetase
EP12_11250	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
EP12_11255	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EP12_11265	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EP12_11275	ENOG4105ERG	peptidase m48, ste24p
EP12_11280	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
EP12_11290	ENOG4105CS1	NAD(P)H quinone oxidoreductase
EP12_11330	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
EP12_11350	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
EP12_11385	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
EP12_11400	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
EP12_11405	ENOG4105C3Q	Glycosyl transferase, family 2
EP12_11415	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EP12_11420	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EP12_11425	ENOG4107QI1	Mate efflux family protein
EP12_11445	ENOG4105C6T	cysteine synthase
EP12_11475	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EP12_11480	ENOG41060WC	Enoyl-CoA hydratase
EP12_11500	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
EP12_11505	ENOG4105C28	cystathionine
EP12_11520	ENOG4105CGF	Aromatic amino acid aminotransferase
EP12_11540	ENOG4108UPT	UPF0178 protein
EP12_11545	ENOG4105CHR	reductase
EP12_11550	ENOG4105CHR	reductase
EP12_11555	ENOG4105CSU	acyl-Coa dehydrogenase
EP12_11560	ENOG41063TF	transcriptional regulator (AraC
EP12_11595	ENOG4105C10	Electron transfer flavoprotein
EP12_11600	ENOG4105BZJ	Electron transfer flavoprotein
EP12_11610	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
EP12_11615	ENOG4108YX2	DNA-binding protein
EP12_11620	ENOG4105EV9	Alpha Beta Hydrolase
EP12_11630	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
EP12_11640	ENOG41090R7	Ferric uptake
EP12_11660	ENOG4105E7W	lamb ycsf family protein
EP12_11665	ENOG4105QNR	S1 RNA binding domain protein
EP12_11670	ENOG4108UKZ	OsmC family
EP12_11690	ENOG4105DK2	UPF0207 protein
EP12_11695	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
EP12_11700	ENOG4108UAJ	Transcriptional regulator
EP12_11710	ENOG4107ZSV	Receptor
EP12_11715	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
EP12_11725	ENOG4105W39	Membrane
EP12_11735	ENOG4105K5B	UPF0225 protein
EP12_11750	ENOG4108R6G	acetyltransferase
EP12_11755	ENOG4105BZU	Histidine kinase
EP12_11770	ENOG4105F8V	Hydrolase, tatD family
EP12_11775	ENOG4107QRG	dna polymerase iii
EP12_11780	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
EP12_11785	ENOG4105HHA	aminodeoxychorismate lyase
EP12_11810	ENOG4105C1G	acyl-Coa dehydrogenase
EP12_11835	ENOG4105D4P	Coproporphyrinogen iii oxidase
EP12_11845	ENOG4105E0C	molybdate abc transporter
EP12_11855	ENOG4108ZAF	Molybdopterin
EP12_11860	ENOG4105M00	molybdopterin converting factor, subunit 1
EP12_11865	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EP12_11870	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
EP12_11875	ENOG4105D06	uba thif-type nad fad binding protein
EP12_11895	ENOG4105CHM	Aminotransferase
EP12_11900	ENOG4105EG6	Saccharopine dehydrogenase
EP12_11905	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EP12_11930	ENOG4107QYX	exodeoxyribonuclease v alpha
EP12_11940	ENOG4105DSY	exodeoxyribonuclease V, gamma
EP12_11955	ENOG4108IQE	Amp-dependent synthetase and ligase
EP12_11960	ENOG4105BZU	Histidine kinase
EP12_11970	ENOG4108YXG	UPF0502 protein
EP12_11985	ENOG4105CVI	Transcriptional regulator
EP12_12000	ENOG4108WFC	UPF0438 protein yifE
EP12_12010	ENOG41082SX	arsR family transcriptional regulator
EP12_12030	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EP12_12095	ENOG4105VUT	cytoplasmic protein
EP12_12105	ENOG4105BZG	amino acid carrier protein
EP12_12130	ENOG4105E0X	reductase
EP12_12135	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
EP12_12150	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
EP12_12160	ENOG4105DSB	aldose 1-epimerase
EP12_12170	ENOG4108UHU	Aldolase
EP12_12175	ENOG4105CHC	glucokinase (EC 2.7.1.2)
EP12_12180	ENOG4105C01	Dihydroxy-acid dehydratase
EP12_12190	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
EP12_12195	ENOG4106KNT	transcriptional regulator
EP12_12200	ENOG4105CA9	Pyruvate kinase
EP12_12205	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
EP12_12245	ENOG4105EB3	Histidine kinase
EP12_12250	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EP12_12275	ENOG4105EIG	urea carboxylase-associated protein 1
EP12_12290	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
EP12_12295	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
EP12_12315	ENOG4105CTX	dehydratase
EP12_12320	ENOG4105D2H	Uronic isomerase
EP12_12325	ENOG4105DEI	Mannitol dehydrogenase
EP12_12330	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
EP12_12335	ENOG4107TDE	lipolytic protein G-D-S-L family
EP12_12345	ENOG4107XII	Glycosyl Hydrolase Family 88
EP12_12355	ENOG4105NBR	Pectinesterase
EP12_12375	ENOG4105BZS	acriflavin resistance protein
EP12_12390	ENOG4105DKW	ABC transporter
EP12_12410	ENOG4105CXK	mandelate racemase muconate lactonizing
EP12_12415	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
EP12_12430	ENOG4105BZU	Histidine kinase
EP12_12455	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EP12_12460	ENOG4105E0F	Histidine kinase
EP12_12470	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EP12_12480	ENOG4105C8P	)-transporter
EP12_12485	ENOG4105DHP	deoxycytidine triphosphate deaminase
EP12_12490	ENOG4105D1F	ATP-binding protein
EP12_12495	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
EP12_12500	ENOG4105D1A	Methyltransferase
EP12_12505	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EP12_12525	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
EP12_12530	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
EP12_12535	ENOG4105G6Z	alkaline phosphatase
EP12_12540	ENOG4105G6Z	alkaline phosphatase
EP12_12560	ENOG4105CIS	alcohol dehydrogenase
EP12_12565	ENOG4108R4R	Iron-regulated virulence regulatory protein
EP12_12570	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
EP12_12575	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
EP12_12585	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
EP12_12590	ENOG4105E96	Colicin v production protein
EP12_12595	ENOG4108S3P	Sporulation domain protein
EP12_12600	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
EP12_12605	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
EP12_12635	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EP12_12730	ENOG4105D8T	Acyltransferase
EP12_12740	ENOG4108UH6	UPF0754 membrane protein
EP12_12770	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
EP12_12780	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
EP12_12785	ENOG4108428	Inherit from COG: -acetyltransferase
EP12_12790	ENOG4108ZZ3	UPF0260 protein
EP12_12795	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
EP12_12805	ENOG4105VNG	YcgL domain-containing protein
EP12_12810	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
EP12_12815	ENOG4105CEY	Amp-dependent synthetase and ligase
EP12_12820	ENOG410832A	alpha/beta hydrolase fold
EP12_12835	ENOG41072GX	Peptidase M22 Glycoprotease
EP12_12840	ENOG4105DVT	helicase
EP12_12885	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
EP12_12900	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
EP12_12910	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
EP12_12915	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
EP12_12920	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
EP12_12960	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EP12_12965	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
EP12_12970	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
EP12_12985	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
EP12_12990	ENOG4107QMP	dna polymerase iii subunits gamma and tau
EP12_12995	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
EP12_13005	ENOG4105E18	UPF0276 protein
EP12_13015	ENOG4108HMN	Caspase domain
EP12_13070	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EP12_13075	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
EP12_13080	ENOG4105C34	Pseudouridine synthase
EP12_13085	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EP12_13095	ENOG4105K6V	RNA polymerase
EP12_13110	ENOG4105EMU	Dehydrogenase
EP12_13130	ENOG4106VK6	Flagellar motor protein
EP12_13135	ENOG4105E14	MotA TolQ exbB proton channel
EP12_13140	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EP12_13145	ENOG4105CTB	Polyprenyl synthetase
EP12_13150	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
EP12_13155	ENOG4108ZAI	phosphatidylglycerophosphatase a
EP12_13160	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
EP12_13165	ENOG4107YIM	Involved in the transcription termination process (By similarity)
EP12_13170	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
EP12_13185	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
EP12_13190	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
EP12_13195	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EP12_13200	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EP12_13215	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
EP12_13225	ENOG4105EAC	phosphoserine phosphatase
EP12_13235	ENOG4105EYA	deoxyribonuclease
EP12_13240	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
EP12_13255	ENOG4105C3F	Signal peptidase i
EP12_13260	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
EP12_13280	ENOG4105EMN	RNA polymerase sigma factor
EP12_13300	ENOG4105Y75	tpr repeat protein
EP12_13305	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
EP12_13310	ENOG4108YZY	peptidylprolyl cis-trans isomerase
EP12_13315	ENOG4108YZA	Nitrogen regulatory protein pii
EP12_13320	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
EP12_13355	ENOG4105X0D	Fimbrial protein
EP12_13380	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
EP12_13385	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
EP12_13390	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
EP12_13400	ENOG4105DTN	riboflavin biosynthesis protein ribF
EP12_13405	ENOG4105CJR	Integral membrane protein (MviN
EP12_13410	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
EP12_13430	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EP12_13440	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
EP12_13445	ENOG4105K70	DNA-binding protein
EP12_13450	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EP12_13455	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
EP12_13460	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EP12_13465	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
EP12_13495	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
EP12_13505	ENOG4108R96	Methyltransferase, YaeB family
EP12_13510	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
EP12_13520	ENOG4105HDD	phospholipase
EP12_13525	ENOG4105DGU	Histone deacetylase
EP12_13535	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EP12_13540	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EP12_13545	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EP12_13560	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
EP12_13565	ENOG4105N21	Membrane
EP12_13570	ENOG4105CUT	histidyl-tRNA synthetase
EP12_13575	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
EP12_13590	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EP12_13595	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
EP12_13600	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
EP12_13610	ENOG4108Z4V	iron-sulfur cluster assembly
EP12_13620	ENOG4105JRK	feS assembly protein SufD
EP12_13625	ENOG4105C3K	feS assembly ATPase SufC
EP12_13635	ENOG4105C3J	Cysteine desulfurase
EP12_13645	ENOG4105D7W	serine acetyltransferase
EP12_13650	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
EP12_13670	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EP12_13675	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EP12_13680	ENOG4105VIE	preprotein translocase, subunit YajC
EP12_13685	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
EP12_13690	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
EP12_13705	ENOG4108P9J	Phage shock protein A
EP12_13730	ENOG4106032	Glutathionylspermidine synthase
EP12_13745	ENOG4105CSV	Glutaminase
EP12_13750	ENOG4105G6Z	alkaline phosphatase
EP12_13760	ENOG4107RET	Isocitrate lyase
EP12_13820	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
EP12_13855	ENOG4105CAQ	asparagine synthetase
EP12_13865	ENOG4105CG5	Glycosyl transferase (Group 1
EP12_13925	ENOG4105E2K	Glycosyl transferase (Group 1
EP12_13930	ENOG4105JNK	Glycosyl transferase (Group 1
EP12_13950	ENOG4105D3Q	Sugar transferase
EP12_13965	ENOG4108QV3	biosynthesis protein
EP12_13985	ENOG41082IR	Excinuclease ABC C subunit domain protein
EP12_14005	ENOG4105D1S	lipid A biosynthesis
EP12_14015	ENOG4107QPN	acyl-Coa dehydrogenase
EP12_14030	ENOG4105BZU	Histidine kinase
EP12_14035	ENOG4107104	thymidine kinase
EP12_14045	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
EP12_14080	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
EP12_14085	ENOG4108RWN	rrna methyltransferase
EP12_14115	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EP12_14130	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
EP12_14165	ENOG4107XDR	Lactoylglutathione lyase
EP12_14175	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
EP12_14180	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
EP12_14185	ENOG4105C7W	Xanthine dehydrogenase
EP12_14190	ENOG4108RCM	Nitroreductase
EP12_14205	ENOG4105FQP	Beta-lactamase
EP12_14250	ENOG4108Z0Z	intracellular protease Pfpi family
EP12_14265	ENOG4105DUM	transcriptional regulator, lysR family
EP12_14275	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
EP12_14285	ENOG4105EMN	RNA polymerase sigma factor
EP12_14315	ENOG4107RNH	Outer membrane receptor FepA
EP12_14330	ENOG4107U9T	Pfam:Ribonuclease_BN
EP12_14355	ENOG4105CNM	Receptor
EP12_14375	ENOG4105NA0	Transcriptional regulator
EP12_14405	ENOG4108VWS	Yaeq family
EP12_14425	ENOG4105T16	Transcriptional regulator (AraC family)
EP12_14435	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
EP12_14440	ENOG4105CT4	transporter
EP12_14445	ENOG4105DT9	hydrolase family 43
EP12_14450	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
EP12_14460	ENOG4105CV1	Transketolase (EC 2.2.1.1)
EP12_14465	ENOG4105C93	Xylose Isomerase
EP12_14480	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
EP12_14520	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EP12_14525	ENOG4108MXF	Alpha Beta Hydrolase
EP12_14545	ENOG4105BZU	Histidine kinase
EP12_14550	ENOG4105GFR	rna polymerase sigma factor
EP12_14560	ENOG4108Z9K	Osmotically inducible protein
EP12_14565	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
EP12_14570	ENOG4105BZU	Histidine kinase
EP12_14580	ENOG4108IUW	ABC transporter
EP12_14585	ENOG4105C1J	atp-dependent rna helicase
EP12_14600	ENOG4105MP9	class II Aldolase
EP12_14625	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
EP12_14670	ENOG4105DZX	CRISPR-associated protein, Csy2 family
EP12_14750	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EP12_14755	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
EP12_14760	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EP12_14770	ENOG4105DC7	peptidase M24
EP12_14780	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
EP12_14785	ENOG4105D0A	hydroxylase
EP12_14790	ENOG4107RAQ	aminopeptidase
EP12_14800	ENOG4108RVA	ribokinase
EP12_14805	ENOG4105DU0	nucleoside hydrolase
EP12_14810	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
EP12_14815	ENOG4105E66	phosphoriboisomerase A
EP12_14820	ENOG4108JQ1	Dehydrogenase
EP12_14860	ENOG4107QN2	dihydrolipoyl dehydrogenase
EP12_14865	ENOG4107QSN	dihydrolipoamide acetyltransferase
EP12_14870	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
EP12_14880	ENOG41073TP	transcriptional regulator
EP12_14895	ENOG4108WIW	Aspartyl protease
EP12_14900	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
EP12_14905	ENOG4108ZUW	Major pilin subunit
EP12_14910	ENOG4105D7Q	type ii secretion system
EP12_14920	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
EP12_14925	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
EP12_14930	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
EP12_14945	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
EP12_14970	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
EP12_14985	ENOG4105DR5	peptidase
EP12_14990	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EP12_14995	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
EP12_15000	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
EP12_15005	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
EP12_15010	ENOG4105CPF	Cell wall formation (By similarity)
EP12_15015	ENOG4105DFU	Cell wall formation (By similarity)
EP12_15025	ENOG4105CNI	cell division protein FtsW
EP12_15030	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
EP12_15040	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
EP12_15055	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
EP12_15060	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
EP12_15065	ENOG4108V6E	Cell division protein mraZ
EP12_15075	ENOG4108IGT	Dipeptidase
EP12_15080	ENOG4108IJF	Heavy metal efflux pump, CzcA
EP12_15105	ENOG4105EHV	domain protein
EP12_15120	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EP12_15140	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EP12_15185	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
EP12_15195	ENOG4105D7Z	glutathione synthase
EP12_15200	ENOG4108UJU	UPF0301 protein
EP12_15205	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
EP12_15215	ENOG4105CZX	twitching motility protein
EP12_15220	ENOG4105CZX	twitching motility protein
EP12_15225	ENOG4105DFA	alanine racemase domain protein
EP12_15230	ENOG4105II7	pyrroline-5-carboxylate reductase
EP12_15235	ENOG4108VIA	integral membrane protein
EP12_15275	ENOG4108UMN	azlc family
EP12_15290	ENOG4105D1Q	UPF0246 protein
EP12_15295	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
EP12_15300	ENOG4107QP8	phosphohexose isomerase
EP12_15310	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
EP12_15315	ENOG4105D98	threonine synthase
EP12_15320	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
EP12_15330	ENOG4105CC0	LysR family Transcriptional regulator
EP12_15345	ENOG4105KBH	arsR family transcriptional regulator
EP12_15355	ENOG4105CAU	Arsenical resistance protein, ArsH
EP12_15360	ENOG4105D6J	arsenicaL-resistance protein
EP12_15365	ENOG4107YTP	response regulator receiver protein
EP12_15370	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
EP12_15380	ENOG4108JA5	May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity)
EP12_15405	ENOG4105E3Q	saccharopine dehydrogenase
EP12_15420	ENOG4105BZU	Histidine kinase
EP12_15425	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
EP12_15435	ENOG41082RQ	UPF0102 protein
EP12_15440	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
EP12_15445	ENOG4105W4M	Transport-associated protein
EP12_15450	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EP12_15470	ENOG4105CR4	methylisocitrate lyase
EP12_15475	ENOG4105BZN	citrate synthase
EP12_15485	ENOG4105C7F	AcnD-accessory protein PrpF
EP12_15490	ENOG4105BZU	Histidine kinase
EP12_15510	ENOG4105BZU	Histidine kinase
EP12_15515	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
EP12_15525	ENOG4105CBC	glutamate synthase
EP12_15530	ENOG4105BZ8	glutamate synthase
EP12_15545	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
EP12_15585	ENOG4105DMF	Dehydrogenase
EP12_15590	ENOG4105C9F	isomerase
EP12_15610	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
EP12_15620	ENOG4105CHR	reductase
EP12_15630	ENOG4105CT4	transporter
EP12_15635	ENOG4105F5H	Glycosyl Hydrolase Family 88
EP12_15640	ENOG4105EKC	
EP12_15650	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
EP12_15665	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
EP12_15675	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
EP12_15680	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
EP12_15685	ENOG4105E4C	Lytic transglycosylase catalytic
EP12_15690	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
EP12_15695	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EP12_15710	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EP12_15720	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
EP12_15725	ENOG4108U78	Glutathione S-transferase
EP12_15730	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
EP12_15745	ENOG4105CSR	polyphosphate kinase 2
EP12_15750	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
EP12_15755	ENOG4107QMS	site-determining protein
EP12_15760	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
EP12_15765	ENOG4105C9Q	fumarate hydratase class II
EP12_15790	ENOG4108YXA	Membrane
EP12_15805	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
EP12_15830	ENOG4105C5F	glutamine synthetase
EP12_15840	ENOG4105CUX	Signal transduction histidine kinase
EP12_15845	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EP12_15850	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EP12_15855	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
EP12_15860	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
EP12_15880	ENOG4105BZU	Histidine kinase
EP12_15885	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
EP12_15890	ENOG4105MYG	DNA polymerase iii, chi subunit
EP12_15895	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EP12_15910	ENOG4105C8Q	Methyl-accepting chemotaxis
EP12_15915	ENOG4105WYW	fructose-bisphosphate aldolase
EP12_15945	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EP12_15955	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
EP12_15960	ENOG4105CP7	Triose-phosphate isomerase
EP12_15965	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EP12_15970	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EP12_15975	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
EP12_15980	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EP12_15985	ENOG4108IJ9	(ABC) transporter
EP12_16000	ENOG4108M8S	permease YjgP YjgQ family protein
EP12_16005	ENOG4108K5H	permease YjgP YjgQ family protein
EP12_16035	ENOG4105CHR	reductase
EP12_16045	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
EP12_16135	ENOG4105CNT	hydrolase family 2
EP12_16155	ENOG4105CXK	mandelate racemase muconate lactonizing
EP12_16160	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
EP12_16180	ENOG4108KPZ	tonB-dependent Receptor
EP12_16215	ENOG4107SDU	Methyl-accepting chemotaxis
EP12_16220	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
EP12_16240	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
EP12_16250	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
EP12_16305	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
EP12_16325	ENOG41088PD	hydrolase
EP12_16340	ENOG4105E2Y	ABC, transporter
EP12_16365	ENOG4105C1J	atp-dependent rna helicase
EP12_16370	ENOG4108UHU	Aldolase
EP12_16375	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
EP12_16390	ENOG4105EGS	Mechanosensitive ion channel
EP12_16410	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
EP12_16420	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
EP12_16435	ENOG4105X23	Endonuclease Exonuclease phosphatase
EP12_16450	ENOG4105HF0	Membrane
EP12_16455	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EP12_16475	ENOG4105CQ2	DNA polymerase
EP12_16510	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
EP12_16525	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
EP12_16535	ENOG4108RG0	uracil-dna glycosylase
EP12_16540	ENOG4105BZU	Histidine kinase
EP12_16550	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
EP12_16555	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
EP12_16560	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
EP12_16585	ENOG41087YS	Phage shock protein A
EP12_16600	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EP12_16620	ENOG4108KTU	conserved protein with FAD NAD(P)-binding domain
EP12_16645	ENOG4105C4W	S-formylglutathione hydrolase
EP12_16650	ENOG4106HNH	Acyl-transferase
EP12_16655	ENOG4106HNH	Acyl-transferase
EP12_16675	ENOG4108535	NAD dependent epimerase/dehydratase family
EP12_16680	ENOG4105C8J	)-transporter
EP12_16695	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
EP12_16710	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
EP12_16720	ENOG4109015	Biopolymer transport protein exbD tolR
EP12_16730	ENOG4105EJG	cellulose synthase
EP12_16735	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
EP12_16760	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
EP12_16775	ENOG4105KWG	Pfam:DUF1696
EP12_16780	ENOG4105BZU	Histidine kinase
EP12_16790	ENOG4105EFZ	amidohydrolase
EP12_16795	ENOG4105C5X	domain protein
EP12_16805	ENOG4108WAV	Transcriptional regulator
EP12_16830	ENOG4105E7A	Glutamine amidotransferase
EP12_16855	ENOG4108YXU	transcriptional regulator AsnC family
EP12_16875	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EP12_16890	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
EP12_16895	ENOG4105C6Z	Gluconate
EP12_16900	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
EP12_16905	ENOG4105K2J	Transcriptional regulator
EP12_16920	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
EP12_16935	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
EP12_16940	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EP12_16945	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EP12_16955	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EP12_16960	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EP12_16965	ENOG4105RKW	reductase (By
EP12_16970	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EP12_16975	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
EP12_16995	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
EP12_17000	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
EP12_17005	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EP12_17020	ENOG4108KPZ	tonB-dependent Receptor
EP12_17035	ENOG4105DBI	uridine monophosphokinase
EP12_17040	ENOG4105D9N	nucleoside
EP12_17070	ENOG4107QN1	sodium solute
EP12_17080	ENOG4105BZU	Histidine kinase
EP12_17090	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EP12_17100	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EP12_17115	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EP12_17130	ENOG4105CPC	Aldo Keto reductase
EP12_17145	ENOG4105CH6	catalase
EP12_17255	ENOG41063Z6	transcriptional regulator, lysR family
EP12_17290	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
EP12_17295	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
EP12_17300	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
EP12_17320	ENOG4105K64	Glycosyl transferase, family 2
EP12_17325	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
EP12_17335	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
EP12_17365	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
EP12_17370	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EP12_17400	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
EP12_17415	ENOG4108ZT0	50S ribosomal protein l17
EP12_17420	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EP12_17425	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
EP12_17430	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
EP12_17435	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EP12_17440	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
EP12_17445	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
EP12_17450	ENOG4105VPB	50S ribosomal protein L30
EP12_17455	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
EP12_17460	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
EP12_17465	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
EP12_17470	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
EP12_17475	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
EP12_17480	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EP12_17485	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
EP12_17490	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
EP12_17505	ENOG4105C2N	RNA methyltransferase TrmH family group 3
EP12_17525	ENOG4108UV7	flagellar protein motX
EP12_17540	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
EP12_17545	ENOG4107QK7	reductase
EP12_17555	ENOG4107VAM	peptidase, m28
EP12_17595	ENOG4105C4M	(Ubiquinol oxidase) subunit I
EP12_17600	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
EP12_17615	ENOG4105VEQ	Cold shock protein
EP12_17620	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
EP12_17630	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EP12_17640	ENOG4105DGW	oligopeptidase A
EP12_17645	ENOG4107YTP	response regulator receiver protein
EP12_17655	ENOG4105BZU	Histidine kinase
EP12_17665	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EP12_17670	ENOG4105DC8	reductase
EP12_17675	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
EP12_17690	ENOG4108JJA	ABC, transporter
EP12_17710	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
EP12_17715	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
EP12_17720	ENOG41063M6	Cell Division Protein
EP12_17725	ENOG4105C25	Primosomal protein n'
EP12_17730	ENOG4105VFB	Binds the 23S rRNA (By similarity)
EP12_17740	ENOG4105C6K	Malic enzyme
EP12_17745	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
EP12_17750	ENOG4105SYT	Methylenetetrahydrofolate reductase
EP12_17755	ENOG4107S2Z	UPF0761 membrane protein
EP12_17775	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
EP12_17780	ENOG4105SUU	thioesterase domain
EP12_17785	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EP12_17800	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
EP12_17805	ENOG4105CAK	Cell division ATP-binding protein ftsE
EP12_17810	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EP12_17820	ENOG4105R2J	Conserved Protein
EP12_17825	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
EP12_17835	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EP12_17840	ENOG4105PW4	Sugar fermentation stimulation protein homolog
EP12_17845	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EP12_17855	ENOG4105DJ0	Poly(A) Polymerase
EP12_17860	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EP12_17865	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
EP12_17870	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
EP12_17875	ENOG4105DY8	decarboxylase
EP12_17890	ENOG4105DA5	(ABC) transporter
EP12_17900	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EP12_17905	ENOG4105EB3	Histidine kinase
EP12_17910	ENOG4108ESX	Receptor
EP12_17915	ENOG4107E2E	PKHD-type hydroxylase
EP12_17935	ENOG4108PJD	permease
EP12_17940	ENOG4105D22	carbon starvation protein
EP12_17955	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EP12_17985	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
EP12_17990	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
EP12_18000	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EP12_18010	ENOG4108VZM	50s ribosomal protein L10
EP12_18020	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EP12_18035	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
EP12_18040	ENOG4105PM1	preprotein translocase subunit SecE
EP12_18060	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EP12_18065	ENOG4105JSC	dimethylmenaquinone methyltransferase
EP12_18095	ENOG4105QNF	Outer membrane lipoprotein
EP12_18100	ENOG4107QM2	Aldo Keto reductase
EP12_18110	ENOG4105DP8	Major facilitator superfamily MFS_1
EP12_18120	ENOG4105EUJ	GTP cyclohydrolase i
EP12_18130	ENOG4105DWY	Agmatine deiminase
EP12_18145	ENOG4105BZU	Histidine kinase
EP12_18155	ENOG4105CF7	AraC family transcriptional regulator
EP12_18210	ENOG4107QRT	dEAD DEAH box helicase
EP12_18220	ENOG4107T0X	DNA ligase
EP12_18240	ENOG4105CYM	Glutathione S-transferase
EP12_18250	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EP12_18275	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
EP12_18290	ENOG4107QJR	hflk protein
EP12_18295	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
EP12_18300	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
EP12_18305	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
EP12_18320	ENOG4105K8N	protein family UPF0079, ATPase
EP12_18330	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
EP12_18355	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
EP12_18360	ENOG4105MYN	Zinc uptake regulation protein
EP12_18370	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
EP12_18375	ENOG4105CDV	Ompa motb domain protein
EP12_18410	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
EP12_18415	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
EP12_18420	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
EP12_18425	ENOG4105BZU	Histidine kinase
EP12_18450	ENOG41060NJ	transcriptional regulator
EP12_18480	ENOG4108Z4X	TRANSCRIPTIONal
EP12_18500	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
EP12_18520	ENOG4105D05	Receptor
EP12_18540	ENOG4105BZU	Histidine kinase
EP12_18560	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
EP12_18565	ENOG4105C4M	(Ubiquinol oxidase) subunit I
EP12_18620	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EP12_18670	ENOG4105VDW	Csbd family
EP12_18675	ENOG4108UDW	Transcriptional regulator, luxr family
EP12_18685	ENOG4105D05	Receptor
EP12_18695	ENOG4107RDJ	Sulfotransferase
EP12_18710	ENOG4105DWD	nucleoside recognition domain protein
EP12_18740	ENOG4105CHM	Aminotransferase
EP12_18750	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
EP12_18755	ENOG4105CEU	Arginine dihydrolase
EP12_18780	ENOG4105EMN	RNA polymerase sigma factor
EP12_18805	ENOG4108YZN	class I peptide chain release factor
EP12_18810	ENOG4108MUZ	hydrolase
EP12_18860	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
EP12_18865	ENOG4105BZU	Histidine kinase
EP12_18895	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EP12_18905	ENOG4107RUZ	Sss sodium solute transporter superfamily
EP12_18930	ENOG4106IBS	oxygenase
EP12_18935	ENOG4105HMI	Membrane
EP12_18970	ENOG4105E98	transcriptional regulator DeoR family
EP12_18975	ENOG4105D9R	oxidoreductase
EP12_19000	ENOG4108K2B	transcriptional regulator
EP12_19025	ENOG4105W8H	transhydrogenase (subunit alpha
EP12_19030	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EP12_19065	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
EP12_19080	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
EP12_19090	ENOG4105BZ9	Cytochrome C oxidase, subunit I
EP12_19110	ENOG4105E3J	oxidoreductase
EP12_19145	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
EP12_19150	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
EP12_19165	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
EP12_19175	ENOG4105E2B	Taurine dioxygenase
EP12_19200	ENOG4105VF7	tolerance protein
EP12_19215	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
EP12_19220	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EP12_19285	ENOG4105DC1	bifunctional purine biosynthesis protein purh
EP12_19295	ENOG4105C12	Phosphoribosylglycinamide synthetase
EP12_19325	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
EP12_19345	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
EP12_19350	ENOG4105VEJ	Heat shock protein
EP12_19375	ENOG4108VAU	general secretion pathway protein G
EP12_19420	ENOG4105C26	Dehydrogenase
EP12_19430	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
EP12_19455	ENOG4105DJ9	glucan biosynthesis protein
EP12_19465	ENOG4105YP7	UPF0270 protein
EP12_19505	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EP12_19515	ENOG4108RRZ	Transcription elongation factor GreB
EP12_19540	ENOG4105MJ2	Competence protein
EP12_19550	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
EP12_19580	ENOG4107R73	Mate efflux family protein
EP12_19600	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
EP12_19645	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
EP12_19650	ENOG4105E0K	tonB-dependent siderophore receptor
EP12_19665	ENOG4105C7B	Threonine dehydratase
EP12_19675	ENOG4105EN6	Membrane
EP12_19685	ENOG4105EMY	transcriptional regulator
EP12_19695	ENOG4105C2C	drug resistance transporter, Bcr CflA
EP12_19700	ENOG4105CFU	surface antigen
EP12_19725	ENOG4105C5I	Dehydrogenase
EP12_19800	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
EP12_19805	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
EP12_19845	ENOG4108YGG	dna repair protein
EP12_19890	ENOG4105C4R	Atp-dependent dna helicase
EP12_19980	ENOG4105CT4	transporter
EP12_19995	ENOG4105KCK	Peptidoglycan-associated lipoprotein
EP12_20000	ENOG4105CPI	Metal Dependent Phosphohydrolase
EP12_20020	ENOG4108K3A	Glutathione S-transferase
EP12_20035	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
EP12_20040	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
EP12_20045	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
EP12_20050	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
EP12_20055	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EP12_20060	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EP12_20065	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EP12_20070	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
EP12_20080	ENOG4105FA0	parb-like partition protein
EP12_20085	ENOG4107QJE	Chromosome Partitioning Protein
EP12_20090	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
EP12_20095	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
EP12_20110	ENOG4105QTB	Flavodoxin
EP12_20115	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
EP12_20120	ENOG4108VPT	UPF0234 protein
EP12_20125	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EP12_20130	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)