locus-tag	class	description
MASE_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MASE_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MASE_00020	COG0187	DNA topoisomerase II activity
MASE_00050	COG2818	Glycosylase
MASE_00060	COG3078	GTPase activator activity
MASE_00080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MASE_00080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MASE_00085	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
MASE_00090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MASE_00095	COG0569	domain protein
MASE_00100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MASE_00100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MASE_00105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MASE_00120	COG0758	DNA mediated transformation
MASE_00135	COG0009	L-threonylcarbamoyladenylate synthase
MASE_00140	COG0408	coproporphyrinogen oxidase activity
MASE_00145	COG3047	cAMP biosynthetic process
MASE_00160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MASE_00215	COG2234	aminopeptidase activity
MASE_00225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MASE_00250	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MASE_00280	COG3642	lipopolysaccharide core region biosynthetic process
MASE_00310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MASE_00325	COG3161	chorismate lyase activity
MASE_00330	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MASE_00340	COG0210	DNA helicase
MASE_00360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MASE_00420	COG0583	DNA-binding transcription factor activity
MASE_00430	COG3106	COG3106 Predicted ATPase
MASE_00445	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MASE_00460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MASE_00465	COG0352	thiamine-phosphate diphosphorylase activity
MASE_00480	COG2959	enzyme of heme biosynthesis
MASE_00490	COG0181	hydroxymethylbilane synthase activity
MASE_00495	COG3706	GGDEF domain
MASE_00495	COG0745	RESPONSE REGULATOR receiver
MASE_00505	COG0194	GDP metabolic process
MASE_00515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MASE_00525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MASE_00545	COG0678	peroxiredoxin activity
MASE_00560	COG1178	ABC-type Fe3 transport system permease component
MASE_00565	COG3842	ATPase activity
MASE_00570	COG2081	HI0933 family
MASE_00575	COG3047	cAMP biosynthetic process
MASE_00590	COG2200	EAL domain
MASE_00595	COG5001	Diguanylate cyclase
MASE_00610	COG2076	Multidrug Resistance protein
MASE_00625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MASE_00640	COG0427	acetyl-CoA hydrolase
MASE_00645	COG0123	including yeast histone deacetylase and acetoin utilization protein
MASE_00660	COG0840	transmembrane signaling receptor activity
MASE_00670	COG3064	Membrane
MASE_00680	COG5002	protein histidine kinase activity
MASE_00680	COG5001	Diguanylate cyclase
MASE_00695	COG0514	ATP-dependent DNA helicase (RecQ)
MASE_00700	COG2050	protein possibly involved in aromatic compounds catabolism
MASE_00705	COG2239	Acts as a magnesium transporter
MASE_00710	COG2962	Rard protein
MASE_00725	COG0210	DNA helicase
MASE_00735	COG3706	GGDEF domain
MASE_00740	COG1011	Hydrolase
MASE_00755	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MASE_00760	COG0019	diaminopimelate decarboxylase activity
MASE_00795	COG0163	prenyltransferase activity
MASE_00800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MASE_00810	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MASE_00845	COG1077	Cell shape determining protein MreB Mrl
MASE_00855	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MASE_00860	COG2814	Major facilitator Superfamily
MASE_00865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MASE_00900	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MASE_00910	COG0629	single-stranded DNA binding
MASE_00930	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MASE_00945	COG1349	DNA-binding transcription factor activity
MASE_00990	COG3267	Type II secretory pathway component ExeA
MASE_00990	COG3409	Peptidoglycan-binding domain 1 protein
MASE_01000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MASE_01005	COG1459	type II secretion system
MASE_01050	COG1077	Cell shape determining protein MreB Mrl
MASE_01055	COG1792	Involved in formation and maintenance of cell shape
MASE_01060	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MASE_01070	COG1530	ribonuclease E activity
MASE_01080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MASE_01085	COG0312	modulator of DNA gyrase
MASE_01095	COG3028	Belongs to the UPF0307 family
MASE_01100	COG0312	modulator of DNA gyrase
MASE_01115	COG0745	RESPONSE REGULATOR receiver
MASE_01120	COG4191	Histidine kinase
MASE_01120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MASE_01125	COG0297	glycogen (starch) synthase activity
MASE_01135	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MASE_01170	COG0745	RESPONSE REGULATOR receiver
MASE_01180	COG0835	chemotaxis
MASE_01195	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MASE_01210	COG0745	RESPONSE REGULATOR receiver
MASE_01215	COG2198	Histidine kinase
MASE_01215	COG0643	Histidine kinase
MASE_01220	COG0835	chemotaxis
MASE_01240	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MASE_01290	COG0546	phosphoglycolate phosphatase activity
MASE_01320	COG1609	Transcriptional regulator
MASE_01325	COG0673	inositol 2-dehydrogenase activity
MASE_01335	COG2211	Major facilitator Superfamily
MASE_01360	COG1454	alcohol dehydrogenase
MASE_01410	COG0089	rRNA binding
MASE_01420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MASE_01430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MASE_01445	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MASE_01455	COG1519	Transferase
MASE_01500	COG0788	formyltetrahydrofolate deformylase activity
MASE_01510	COG1643	Atp-dependent helicase
MASE_01520	COG2951	lytic endotransglycosylase activity
MASE_01525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MASE_01540	COG2354	Protein conserved in bacteria
MASE_01565	COG0004	ammonium transporteR
MASE_01570	COG0405	Gamma-glutamyltransferase
MASE_01575	COG2837	iron assimilation
MASE_01590	COG0540	Belongs to the ATCase OTCase family
MASE_01615	COG0784	Response regulator, receiver
MASE_01615	COG5002	protein histidine kinase activity
MASE_01615	COG2205	protein histidine kinase activity
MASE_01630	COG3300	MHYT domain
MASE_01630	COG5001	Diguanylate cyclase
MASE_01640	COG1012	belongs to the aldehyde dehydrogenase family
MASE_01650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MASE_01660	COG0512	Glutamine amidotransferase of anthranilate synthase
MASE_01665	COG0180	Tryptophanyl-tRNA synthetase
MASE_01670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MASE_01690	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MASE_01700	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MASE_01735	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MASE_01740	COG0281	malic enzyme
MASE_01750	COG0625	glutathione transferase activity
MASE_01760	COG0753	catalase activity
MASE_01785	COG3300	MHYT domain
MASE_01785	COG5001	Diguanylate cyclase
MASE_01805	COG0137	argininosuccinate synthase activity
MASE_01825	COG1803	Methylglyoxal synthase
MASE_01835	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MASE_01850	COG0745	RESPONSE REGULATOR receiver
MASE_01855	COG2205	protein histidine kinase activity
MASE_01860	COG2267	carboxylic ester hydrolase activity
MASE_01865	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MASE_01870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MASE_01875	COG1136	(ABC) transporter
MASE_01875	COG0577	efflux transmembrane transporter activity
MASE_01890	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MASE_01900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MASE_01905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MASE_01910	COG4942	peptidase
MASE_01915	COG2861	carbohydrate metabolic process
MASE_01925	COG0584	glycerophosphoryl diester phosphodiesterase
MASE_01945	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MASE_01975	COG0028	Belongs to the TPP enzyme family
MASE_01995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MASE_02000	COG0805	protein transport
MASE_02010	COG0084	hydrolase, TatD family'
MASE_02015	COG4251	negative regulation of phosphorylation
MASE_02015	COG5001	Diguanylate cyclase
MASE_02015	COG2203	Gaf domain
MASE_02015	COG3706	GGDEF domain
MASE_02025	COG0248	Ppx GppA phosphatase
MASE_02040	COG3118	belongs to the thioredoxin family
MASE_02045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MASE_02060	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MASE_02065	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MASE_02070	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MASE_02080	COG0783	Belongs to the Dps family
MASE_02085	COG2133	pyrroloquinoline quinone binding
MASE_02090	COG1506	peptidase
MASE_02090	COG4946	Tricorn protease homolog
MASE_02090	COG0823	Involved in the tonB-independent uptake of proteins
MASE_02100	COG3118	belongs to the thioredoxin family
MASE_02115	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
MASE_02125	COG1012	belongs to the aldehyde dehydrogenase family
MASE_02150	COG1757	Na H antiporter
MASE_02165	COG3876	Protein conserved in bacteria
MASE_02170	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MASE_02190	COG0346	lactoylglutathione lyase activity
MASE_02225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MASE_02235	COG2824	Alkylphosphonate utilization operon protein PhnA
MASE_02240	COG0454	-acetyltransferase
MASE_02250	COG1742	UPF0060 membrane protein
MASE_02310	COG0183	Belongs to the thiolase family
MASE_02315	COG1024	Enoyl-CoA hydratase
MASE_02315	COG1250	3-hydroxyacyl-CoA dehydrogenase
MASE_02320	COG0741	lytic transglycosylase activity
MASE_02320	COG1196	nuclear chromosome segregation
MASE_02320	COG0739	heme binding
MASE_02325	COG0006	proline dipeptidase activity
MASE_02335	COG0142	geranyltranstransferase activity
MASE_02380	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MASE_02385	COG4942	peptidase
MASE_02385	COG1388	LysM domain
MASE_02390	COG1238	metal cluster binding
MASE_02400	COG0585	pseudouridine synthase activity
MASE_02405	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MASE_02415	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MASE_02425	COG0840	transmembrane signaling receptor activity
MASE_02430	COG1522	sequence-specific DNA binding
MASE_02445	COG0506	proline dehydrogenase activity
MASE_02445	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MASE_02445	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MASE_02470	COG0745	RESPONSE REGULATOR receiver
MASE_02475	COG5002	protein histidine kinase activity
MASE_02500	COG0494	nUDIX hydrolase
MASE_02505	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
MASE_02510	COG0730	response to heat
MASE_02515	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MASE_02520	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MASE_02530	COG3706	GGDEF domain
MASE_02535	COG4999	Histidine kinase
MASE_02535	COG3850	Histidine kinase
MASE_02535	COG3437	response regulator, receiver
MASE_02535	COG2205	protein histidine kinase activity
MASE_02540	COG2211	Major facilitator Superfamily
MASE_02560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MASE_02575	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MASE_02580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MASE_02605	COG1648	precorrin-2 dehydrogenase activity
MASE_02605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MASE_02610	COG0513	Belongs to the DEAD box helicase family
MASE_02630	COG1538	Outer membrane efflux protein
MASE_02635	COG0494	nUDIX hydrolase
MASE_02645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MASE_02650	COG3150	esterase
MASE_02655	COG0187	DNA topoisomerase II activity
MASE_02665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MASE_02685	COG1509	lysine 2,3-aminomutase activity
MASE_02715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MASE_02735	COG0271	Belongs to the BolA IbaG family
MASE_02760	COG3707	response regulator
MASE_02770	COG0659	secondary active sulfate transmembrane transporter activity
MASE_02780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MASE_02785	COG2146	nitrite reductase [NAD(P)H] activity
MASE_02790	COG0243	molybdopterin cofactor binding
MASE_02795	COG1648	precorrin-2 dehydrogenase activity
MASE_02795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MASE_02800	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MASE_02805	COG0737	Belongs to the 5'-nucleotidase family
MASE_02810	COG3706	GGDEF domain
MASE_02810	COG4251	negative regulation of phosphorylation
MASE_02810	COG5001	Diguanylate cyclase
MASE_02810	COG2203	Gaf domain
MASE_02820	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MASE_02820	COG1116	anion transmembrane transporter activity
MASE_02830	COG1116	anion transmembrane transporter activity
MASE_02845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MASE_02850	COG4206	TonB-dependent receptor
MASE_02865	COG0348	domain, Protein
MASE_02880	COG1960	acyl-CoA dehydrogenase activity
MASE_02885	COG1028	Short-chain dehydrogenase reductase Sdr
MASE_02900	COG4948	Mandelate Racemase Muconate Lactonizing
MASE_02915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MASE_02920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MASE_02940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MASE_02945	COG0358	DNA primase activity
MASE_02970	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MASE_02975	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MASE_02990	COG0537	adenosine 5'-monophosphoramidase activity
MASE_03005	COG3135	benzoate transporter
MASE_03010	COG1396	sequence-specific DNA binding
MASE_03015	COG2974	May be involved in recombination
MASE_03020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MASE_03020	COG4191	Histidine kinase
MASE_03025	COG0745	RESPONSE REGULATOR receiver
MASE_03030	COG5002	protein histidine kinase activity
MASE_03060	COG0811	peptide transport
MASE_03065	COG0811	peptide transport
MASE_03070	COG0848	biopolymer transport protein
MASE_03075	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MASE_03085	COG3437	response regulator, receiver
MASE_03100	COG0318	PFAM AMP-dependent synthetase and ligase
MASE_03110	COG2133	pyrroloquinoline quinone binding
MASE_03115	COG1049	propionate catabolic process, 2-methylcitrate cycle
MASE_03150	COG0527	aspartate kinase activity
MASE_03160	COG0840	transmembrane signaling receptor activity
MASE_03165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MASE_03170	COG2967	ApaG domain
MASE_03180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MASE_03185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MASE_03190	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MASE_03195	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MASE_03210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MASE_03215	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MASE_03230	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MASE_03245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MASE_03250	COG3956	TIGRFAM MazG family protein
MASE_03275	COG4771	TonB-dependent receptor
MASE_03295	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MASE_03300	COG0723	plastoquinol--plastocyanin reductase activity
MASE_03305	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MASE_03310	COG2857	Cytochrome c1
MASE_03315	COG0625	glutathione transferase activity
MASE_03320	COG2969	positive regulation of protein catabolic process
MASE_03335	COG0745	RESPONSE REGULATOR receiver
MASE_03340	COG2239	Acts as a magnesium transporter
MASE_03345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MASE_03355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MASE_03365	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MASE_03370	COG1137	ATPase activity
MASE_03375	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MASE_03385	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MASE_03400	COG1127	ABC transporter
MASE_03405	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MASE_03410	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MASE_03415	COG2854	intermembrane phospholipid transfer
MASE_03425	COG5007	Belongs to the BolA IbaG family
MASE_03435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MASE_03440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MASE_03450	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MASE_03490	COG2308	Evidence 4 Homologs of previously reported genes of
MASE_03495	COG1305	Transglutaminase-like
MASE_03515	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MASE_03530	COG4771	TonB-dependent receptor
MASE_03535	COG0697	spore germination
MASE_03545	COG0784	Response regulator, receiver
MASE_03545	COG2205	protein histidine kinase activity
MASE_03570	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MASE_03580	COG0126	phosphoglycerate kinase activity
MASE_03585	COG3588	fructose-bisphosphate aldolase
MASE_03590	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MASE_03600	COG0745	RESPONSE REGULATOR receiver
MASE_03605	COG5002	protein histidine kinase activity
MASE_03635	COG1538	Outer membrane efflux protein
MASE_03645	COG0823	Involved in the tonB-independent uptake of proteins
MASE_03645	COG4946	Tricorn protease homolog
MASE_03645	COG1506	peptidase
MASE_03655	COG0248	Ppx GppA phosphatase
MASE_03660	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MASE_03665	COG2716	regulation of RNA biosynthetic process
MASE_03670	COG0573	inorganic phosphate transmembrane transporter activity
MASE_03680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MASE_03690	COG0306	phosphate transporter
MASE_03700	COG0583	DNA-binding transcription factor activity
MASE_03725	COG1272	protein, Hemolysin III
MASE_03735	COG1846	Transcriptional regulator
MASE_03740	COG1764	response to oxidative stress
MASE_03755	COG1739	Uncharacterized protein family UPF0029
MASE_03775	COG0583	DNA-binding transcription factor activity
MASE_03780	COG4989	oxidoreductase activity
MASE_03790	COG0420	3'-5' exonuclease activity
MASE_03795	COG0419	ATPase involved in DNA repair
MASE_03815	COG0463	Glycosyl transferase, family 2
MASE_03820	COG0745	RESPONSE REGULATOR receiver
MASE_03825	COG5002	protein histidine kinase activity
MASE_03825	COG3850	Histidine kinase
MASE_03830	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MASE_03855	COG2986	histidine ammonia-lyase
MASE_03880	COG0668	transmembrane transport
MASE_03885	COG3866	Pectate lyase
MASE_03895	COG2814	Major facilitator Superfamily
MASE_03940	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MASE_04040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MASE_04045	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MASE_04050	COG0513	Belongs to the DEAD box helicase family
MASE_04070	COG3267	Type II secretory pathway component ExeA
MASE_04070	COG3409	Peptidoglycan-binding domain 1 protein
MASE_04100	COG0473	3-isopropylmalate dehydrogenase activity
MASE_04105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MASE_04130	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MASE_04150	COG2271	Major facilitator Superfamily
MASE_04155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MASE_04165	COG2186	Transcriptional regulator
MASE_04200	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MASE_04215	COG4555	ABC transporter
MASE_04220	COG1668	transmembrane transport
MASE_04240	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MASE_04245	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MASE_04250	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MASE_04260	COG1138	Cytochrome C-type biogenesis protein
MASE_04280	COG2853	Lipoprotein
MASE_04285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MASE_04295	COG3104	oligopeptide transport
MASE_04325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MASE_04340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MASE_04345	COG1555	photosystem II stabilization
MASE_04345	COG1596	polysaccharide export
MASE_04350	COG0473	3-isopropylmalate dehydrogenase activity
MASE_04365	COG1611	Belongs to the LOG family
MASE_04370	COG3706	GGDEF domain
MASE_04370	COG0745	RESPONSE REGULATOR receiver
MASE_04415	COG0564	pseudouridine synthase activity
MASE_04430	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MASE_04435	COG0024	Methionine aminopeptidase
MASE_04440	COG0052	Belongs to the universal ribosomal protein uS2 family
MASE_04450	COG0528	UMP kinase activity
MASE_04460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MASE_04465	COG0575	Belongs to the CDS family
MASE_04475	COG0750	zinc metalloprotease
MASE_04490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MASE_04510	COG0587	DNA-directed DNA polymerase activity
MASE_04515	COG0825	malonyl-CoA metabolic process
MASE_04520	COG0037	tRNA processing
MASE_04540	COG0590	tRNA wobble adenosine to inosine editing
MASE_04555	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MASE_04555	COG0047	phosphoribosylformylglycinamidine synthase activity
MASE_04560	COG2840	Smr protein MutS2
MASE_04590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MASE_04595	COG2197	response regulator
MASE_04635	COG0784	Response regulator, receiver
MASE_04635	COG0835	chemotaxis
MASE_04640	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MASE_04645	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MASE_04650	COG1815	bacterial-type flagellum-dependent cell motility
MASE_04655	COG1558	bacterial-type flagellum-dependent cell motility
MASE_04660	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MASE_04665	COG1749	Flagellar hook protein flgE
MASE_04670	COG4787	bacterial-type flagellum-dependent cell motility
MASE_04675	COG4786	Flagellar basal body rod
MASE_04690	COG1705	Flagellar rod assembly protein muramidase FlgJ
MASE_04690	COG3951	Flagellar rod assembly protein muramidase FlgJ
MASE_04695	COG1256	bacterial-type flagellum assembly
MASE_04710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MASE_04740	COG0463	Glycosyl transferase, family 2
MASE_04760	COG1442	glycosyl transferase family 8
MASE_04770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MASE_04775	COG1086	Polysaccharide biosynthesis protein
MASE_04790	COG3475	LICD family
MASE_04795	COG2089	acid synthase
MASE_04805	COG1083	cytidylyl-transferase
MASE_04810	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MASE_04820	COG2204	response regulator
MASE_04825	COG3852	Histidine kinase
MASE_04830	COG2204	response regulator
MASE_04835	COG1677	Flagellar hook-basal body complex protein FliE
MASE_04840	COG1766	The M ring may be actively involved in energy transduction
MASE_04845	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MASE_04895	COG1987	bacterial-type flagellum assembly
MASE_04915	COG2989	Protein conserved in bacteria
MASE_04920	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MASE_04930	COG0455	bacterial-type flagellum organization
MASE_04945	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
MASE_04965	COG1192	Involved in chromosome partitioning
MASE_04975	COG0835	chemotaxis
MASE_04990	COG1410	methionine synthase
MASE_04990	COG0646	methionine synthase
MASE_04995	COG1410	methionine synthase
MASE_04995	COG0646	methionine synthase
MASE_05005	COG3123	guanosine phosphorylase activity
MASE_05015	COG0583	DNA-binding transcription factor activity
MASE_05020	COG0583	DNA-binding transcription factor activity
MASE_05025	COG0288	reversible hydration of carbon dioxide
MASE_05030	COG0659	secondary active sulfate transmembrane transporter activity
MASE_05040	COG1309	transcriptional regulator
MASE_05045	COG3590	peptidase
MASE_05055	COG2137	regulation of response to DNA damage stimulus
MASE_05060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MASE_05070	COG1607	acyl-coa hydrolase
MASE_05080	COG0511	ligase activity, forming carbon-carbon bonds
MASE_05080	COG5016	pyruvate
MASE_05085	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
MASE_05090	COG4172	Belongs to the ABC transporter superfamily
MASE_05100	COG4171	peptide transport system, permease
MASE_05105	COG4168	peptide transport system, permease
MASE_05110	COG0747	negative chemotaxis
MASE_05115	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MASE_05120	COG1842	Phage shock protein A
MASE_05150	COG0625	glutathione transferase activity
MASE_05155	COG1522	sequence-specific DNA binding
MASE_05160	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MASE_05180	COG0457	Tetratricopeptide repeat
MASE_05225	COG0811	peptide transport
MASE_05230	COG0811	peptide transport
MASE_05235	COG0848	biopolymer transport protein
MASE_05250	COG1444	tRNA N-acetyltransferase activity
MASE_05285	COG0456	acetyltransferase
MASE_05300	COG0583	DNA-binding transcription factor activity
MASE_05305	COG2814	Major facilitator Superfamily
MASE_05310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MASE_05315	COG0656	L-ascorbic acid biosynthetic process
MASE_05335	COG1846	Transcriptional regulator
MASE_05345	COG3275	phosphorelay sensor kinase activity
MASE_05350	COG1966	Carbon starvation protein
MASE_05370	COG0457	Tetratricopeptide repeat
MASE_05385	COG2197	response regulator
MASE_05395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MASE_05405	COG3706	GGDEF domain
MASE_05425	COG0583	DNA-binding transcription factor activity
MASE_05430	COG0702	epimerase
MASE_05450	COG1902	pentaerythritol trinitrate reductase activity
MASE_05460	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MASE_05465	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MASE_05470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MASE_05475	COG0564	pseudouridine synthase activity
MASE_05485	COG0612	Peptidase, M16
MASE_05490	COG2918	glutathione biosynthetic process
MASE_05515	COG2840	Smr protein MutS2
MASE_05520	COG2890	protein-(glutamine-N5) methyltransferase activity
MASE_05535	COG2719	SpoVR family
MASE_05540	COG2718	Belongs to the UPF0229 family
MASE_05545	COG2766	serine protein kinase
MASE_05555	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MASE_05590	COG0450	alkyl hydroperoxide reductase
MASE_05595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MASE_05600	COG2885	chlorophyll binding
MASE_05605	COG0584	glycerophosphoryl diester phosphodiesterase
MASE_05610	COG0346	lactoylglutathione lyase activity
MASE_05615	COG4221	oxidoreductase activity
MASE_05620	COG1278	Cold shock
MASE_05635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MASE_05640	COG4660	Part of a membrane complex involved in electron transport
MASE_05645	COG4659	FMN binding
MASE_05650	COG4658	electron transport chain
MASE_05655	COG4656	Part of a membrane complex involved in electron transport
MASE_05660	COG0534	Mate efflux family protein
MASE_05665	COG0556	nucleotide-excision repair
MASE_05680	COG0602	queuosine metabolic process
MASE_05690	COG0367	asparagine synthase
MASE_05710	COG0471	metal ion transport
MASE_05710	COG3273	potassium ion transport
MASE_05730	COG0529	Catalyzes the synthesis of activated sulfate
MASE_05735	COG0175	sulfate reduction
MASE_05740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MASE_05745	COG0745	RESPONSE REGULATOR receiver
MASE_05745	COG3706	GGDEF domain
MASE_05770	COG2304	oxidoreductase activity
MASE_05790	COG0714	Associated with various cellular activities
MASE_05800	COG1250	3-hydroxyacyl-CoA dehydrogenase
MASE_05800	COG1024	Enoyl-CoA hydratase
MASE_05820	COG1025	Belongs to the peptidase M16 family
MASE_05825	COG2062	phosphohistidine phosphatase, SixA
MASE_05835	COG4536	flavin adenine dinucleotide binding
MASE_05840	COG4137	Cytochrome C assembly protein
MASE_05845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MASE_05890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MASE_05895	COG1132	(ABC) transporter
MASE_05910	COG0228	four-way junction DNA binding
MASE_05915	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MASE_05920	COG0336	Belongs to the RNA methyltransferase TrmD family
MASE_05925	COG0335	large ribosomal subunit rRNA binding
MASE_05930	COG2860	membrane
MASE_05940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MASE_05945	COG1605	Chorismate mutase
MASE_05945	COG0287	Prephenate dehydrogenase
MASE_05975	COG1605	Chorismate mutase
MASE_05975	COG0077	Prephenate dehydratase
MASE_05980	COG0745	RESPONSE REGULATOR receiver
MASE_05985	COG0023	Translation Initiation Factor
MASE_06025	COG2205	protein histidine kinase activity
MASE_06035	COG2204	response regulator
MASE_06050	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MASE_06055	COG0494	nUDIX hydrolase
MASE_06060	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MASE_06070	COG2255	four-way junction helicase activity
MASE_06075	COG0824	Thioesterase
MASE_06080	COG0811	peptide transport
MASE_06095	COG0823	Involved in the tonB-independent uptake of proteins
MASE_06100	COG2885	chlorophyll binding
MASE_06105	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
MASE_06110	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MASE_06120	COG4667	esterase of the alpha-beta hydrolase superfamily
MASE_06125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MASE_06145	COG3038	cytochrome b561
MASE_06165	COG1451	nucleotide metabolic process
MASE_06175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MASE_06185	COG1309	transcriptional regulator
MASE_06190	COG4774	siderophore transport
MASE_06210	COG3706	GGDEF domain
MASE_06220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MASE_06220	COG3008	intermembrane lipid transfer
MASE_06225	COG2995	paraquat-inducible protein a
MASE_06235	COG0017	Asparaginyl-tRNA synthetase
MASE_06250	COG0189	ligase activity
MASE_06285	COG2226	methyltransferase
MASE_06300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MASE_06305	COG4139	cobalamin transport
MASE_06315	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MASE_06320	COG2205	protein histidine kinase activity
MASE_06325	COG0745	RESPONSE REGULATOR receiver
MASE_06330	COG0569	domain protein
MASE_06335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MASE_06350	COG5265	(ABC) transporter
MASE_06355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MASE_06365	COG0745	RESPONSE REGULATOR receiver
MASE_06370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MASE_06390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MASE_06400	COG2755	lipolytic protein G-D-S-L family
MASE_06405	COG4181	ATPase activity
MASE_06410	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MASE_06415	COG1090	epimerase
MASE_06420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MASE_06425	COG0628	permease
MASE_06435	COG0745	RESPONSE REGULATOR receiver
MASE_06450	COG2350	Protein conserved in bacteria
MASE_06455	COG0159	tryptophan synthase activity
MASE_06465	COG0134	indole-3-glycerol-phosphate synthase activity
MASE_06465	COG0135	phosphoribosylanthranilate isomerase activity
MASE_06470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MASE_06480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MASE_06495	COG0009	L-threonylcarbamoyladenylate synthase
MASE_06505	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MASE_06515	COG0656	L-ascorbic acid biosynthetic process
MASE_06520	COG0110	maltose O-acetyltransferase activity
MASE_06540	COG2733	membrane
MASE_06545	COG0500	methyltransferase
MASE_06550	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MASE_06555	COG0497	DNA recombination
MASE_06560	COG0783	Belongs to the Dps family
MASE_06575	COG1454	alcohol dehydrogenase
MASE_06580	COG1028	Short-chain dehydrogenase reductase Sdr
MASE_06590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MASE_06595	COG2610	gluconate transmembrane transporter activity
MASE_06600	COG4771	TonB-dependent receptor
MASE_06615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MASE_06615	COG0784	Response regulator, receiver
MASE_06615	COG2205	protein histidine kinase activity
MASE_06615	COG2198	Histidine kinase
MASE_06625	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MASE_06635	COG0484	heat shock protein binding
MASE_06640	COG3909	cytochrome
MASE_06655	COG2200	EAL domain
MASE_06655	COG2199	diguanylate cyclase activity
MASE_06655	COG2202	Pas domain
MASE_06670	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MASE_06680	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MASE_06685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MASE_06725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MASE_06730	COG0280	phosphate acetyltransferase
MASE_06730	COG0857	belongs to the CobB CobQ family
MASE_06735	COG1228	amidohydrolase
MASE_06740	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MASE_06745	COG4535	Mg2 and Co2 transporter CorC
MASE_06755	COG1702	phosphate starvation-inducible protein PhoH
MASE_06765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MASE_06810	COG1607	acyl-coa hydrolase
MASE_06815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MASE_06825	COG1115	amino acid carrier protein
MASE_06830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MASE_06835	COG0012	GTP binding
MASE_06850	COG1064	alcohol dehydrogenase
MASE_06860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MASE_06865	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MASE_06875	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MASE_06885	COG2890	protein-(glutamine-N5) methyltransferase activity
MASE_06890	COG3437	response regulator, receiver
MASE_06890	COG0784	Response regulator, receiver
MASE_06895	COG3094	Invasion gene expression up-regulator, SirB
MASE_06910	COG0583	DNA-binding transcription factor activity
MASE_06920	COG2363	Small membrane protein
MASE_06935	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MASE_06950	COG2116	formate transmembrane transporter activity
MASE_06965	COG0714	Associated with various cellular activities
MASE_06975	COG0033	Phosphoglucomutase
MASE_06980	COG0058	SHG alpha-glucan phosphorylase activity
MASE_06990	COG2988	succinylglutamate desuccinylase activity
MASE_07005	COG1301	dicarboxylic acid transport
MASE_07025	COG1393	Belongs to the ArsC family
MASE_07050	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MASE_07065	COG3300	MHYT domain
MASE_07065	COG5001	Diguanylate cyclase
MASE_07080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MASE_07100	COG2249	NAD(P)H dehydrogenase (quinone) activity
MASE_07125	COG1733	regulation of RNA biosynthetic process
MASE_07135	COG3447	MASE1 domain protein
MASE_07135	COG5002	protein histidine kinase activity
MASE_07135	COG5001	Diguanylate cyclase
MASE_07145	COG0402	S-adenosylhomocysteine deaminase activity
MASE_07150	COG2351	hydroxyisourate hydrolase activity
MASE_07165	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MASE_07175	COG1309	transcriptional regulator
MASE_07190	COG2252	PERMEase
MASE_07195	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MASE_07210	COG0745	RESPONSE REGULATOR receiver
MASE_07210	COG3706	GGDEF domain
MASE_07215	COG0784	Response regulator, receiver
MASE_07215	COG2205	protein histidine kinase activity
MASE_07230	COG2233	PERMEase
MASE_07235	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MASE_07250	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MASE_07255	COG0730	response to heat
MASE_07265	COG0154	amidase activity
MASE_07300	COG1028	Short-chain dehydrogenase reductase Sdr
MASE_07315	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MASE_07335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MASE_07345	COG1596	polysaccharide export
MASE_07350	COG0489	protein tyrosine kinase activity
MASE_07355	COG4464	protein tyrosine phosphatase activity
MASE_07450	COG0438	transferase activity, transferring glycosyl groups
MASE_07465	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MASE_07465	COG2755	lipolytic protein G-D-S-L family
MASE_07475	COG0072	phenylalanine-tRNA ligase activity
MASE_07475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MASE_07500	COG1472	Belongs to the glycosyl hydrolase 3 family
MASE_07505	COG2096	Adenosyltransferase
MASE_07515	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MASE_07525	COG4591	ABC-type transport system involved in lipoprotein release permease component
MASE_07550	COG0708	Exodeoxyribonuclease III
MASE_07585	COG2814	Major facilitator Superfamily
MASE_07625	COG1024	Enoyl-CoA hydratase
MASE_07630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MASE_07635	COG1960	acyl-CoA dehydrogenase activity
MASE_07640	COG0789	Transcriptional regulator
MASE_07645	COG0183	Belongs to the thiolase family
MASE_07670	COG2925	Exonuclease
MASE_07675	COG0784	Response regulator, receiver
MASE_07675	COG2205	protein histidine kinase activity
MASE_07675	COG5002	protein histidine kinase activity
MASE_07715	COG1643	Atp-dependent helicase
MASE_07735	COG0604	alcohol dehydrogenase
MASE_07735	COG3321	synthase
MASE_07740	COG0328	RNA-DNA hybrid ribonuclease activity
MASE_07745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MASE_07755	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MASE_07760	COG1136	(ABC) transporter
MASE_07765	COG4591	ABC-type transport system involved in lipoprotein release permease component
MASE_07770	COG1301	dicarboxylic acid transport
MASE_07780	COG3724	N-succinylarginine dihydrolase activity
MASE_07785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MASE_07790	COG3122	Protein conserved in bacteria
MASE_07800	COG0583	DNA-binding transcription factor activity
MASE_07805	COG0746	molybdenum cofactor guanylyltransferase activity
MASE_07810	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MASE_07815	COG0243	molybdopterin cofactor binding
MASE_07825	COG0625	glutathione transferase activity
MASE_07840	COG2153	protein acetylation
MASE_07855	COG5002	protein histidine kinase activity
MASE_07865	COG1530	ribonuclease E activity
MASE_07870	COG0564	pseudouridine synthase activity
MASE_07875	COG0546	phosphoglycolate phosphatase activity
MASE_07880	COG0424	maF-like protein
MASE_07885	COG1399	metal-binding, possibly nucleic acid-binding protein
MASE_07895	COG0416	fatty acid biosynthetic process
MASE_07900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MASE_07905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MASE_07915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MASE_07920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MASE_07925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MASE_07930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MASE_07945	COG0084	hydrolase, TatD family'
MASE_07950	COG0259	pyridoxamine-phosphate oxidase activity
MASE_07955	COG0702	epimerase
MASE_07960	COG3706	GGDEF domain
MASE_07985	COG1028	Short-chain dehydrogenase reductase Sdr
MASE_07990	COG0596	Alpha beta hydrolase
MASE_07995	COG1024	Enoyl-CoA hydratase
MASE_07995	COG1250	3-hydroxyacyl-CoA dehydrogenase
MASE_08000	COG0183	Belongs to the thiolase family
MASE_08005	COG1960	acyl-CoA dehydrogenase activity
MASE_08010	COG0596	Alpha beta hydrolase
MASE_08025	COG2390	Transcriptional regulator
MASE_08030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MASE_08040	COG0246	Mannitol dehydrogenase
MASE_08055	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MASE_08060	COG0523	cobalamin synthesis protein
MASE_08065	COG0277	FAD linked oxidase domain protein
MASE_08065	COG0247	lactate metabolic process
MASE_08090	COG0668	transmembrane transport
MASE_08095	COG4771	TonB-dependent receptor
MASE_08105	COG0784	Response regulator, receiver
MASE_08105	COG2205	protein histidine kinase activity
MASE_08105	COG2198	Histidine kinase
MASE_08110	COG3437	response regulator, receiver
MASE_08120	COG0195	Participates in both transcription termination and antitermination
MASE_08135	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MASE_08145	COG3300	MHYT domain
MASE_08145	COG5001	Diguanylate cyclase
MASE_08150	COG1187	pseudouridine synthase activity
MASE_08160	COG3153	acetyltransferase
MASE_08160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MASE_08190	COG0450	alkyl hydroperoxide reductase
MASE_08235	COG1032	radical SAM domain protein
MASE_08250	COG4771	TonB-dependent receptor
MASE_08255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MASE_08265	COG4134	Bacterial extracellular solute-binding protein
MASE_08275	COG4136	ATPase activity
MASE_08280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MASE_08330	COG0583	DNA-binding transcription factor activity
MASE_08335	COG2249	NAD(P)H dehydrogenase (quinone) activity
MASE_08350	COG0583	DNA-binding transcription factor activity
MASE_08370	COG1131	(ABC) transporter
MASE_08380	COG1902	pentaerythritol trinitrate reductase activity
MASE_08390	COG2867	negative regulation of translational initiation
MASE_08395	COG2914	Belongs to the UPF0125 (RnfH) family
MASE_08405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MASE_08410	COG4771	TonB-dependent receptor
MASE_08415	COG0457	Tetratricopeptide repeat
MASE_08435	COG0574	Belongs to the PEP-utilizing enzyme family
MASE_08435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MASE_08470	COG2850	peptidyl-arginine hydroxylation
MASE_08480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MASE_08485	COG2915	High frequency lysogenization protein hflD homolog
MASE_08490	COG0482	sulfurtransferase activity
MASE_08495	COG1187	pseudouridine synthase activity
MASE_08505	COG1278	Cold shock
MASE_08510	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MASE_08515	COG0542	response to heat
MASE_08520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MASE_08525	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MASE_08530	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MASE_08535	COG0492	ferredoxin-NADP+ reductase activity
MASE_08540	COG3092	negative regulation of chromosome organization
MASE_08545	COG3091	SprT-like family
MASE_08550	COG0616	signal peptide processing
MASE_08565	COG0778	Nitroreductase
MASE_08575	COG0252	asparaginase activity
MASE_08580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MASE_08585	COG0321	lipoyl(octanoyl) transferase activity
MASE_08590	COG2921	Belongs to the UPF0250 family
MASE_08595	COG1686	Belongs to the peptidase S11 family
MASE_08600	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MASE_08605	COG0772	Belongs to the SEDS family
MASE_08610	COG0768	penicillin binding
MASE_08615	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MASE_08620	COG0799	negative regulation of ribosome biogenesis
MASE_08625	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MASE_08630	COG1466	dna polymerase III delta subunit
MASE_08635	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
MASE_08640	COG0495	leucyl-tRNA aminoacylation
MASE_08650	COG1067	ATP-dependent peptidase activity
MASE_08670	COG1534	Rna-binding protein
MASE_08675	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MASE_08680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MASE_08685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MASE_08690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MASE_08695	COG0149	triose-phosphate isomerase activity
MASE_08700	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MASE_08725	COG1803	Methylglyoxal synthase
MASE_08725	COG1597	lipid kinase activity
MASE_08735	COG1028	Short-chain dehydrogenase reductase Sdr
MASE_08740	COG0561	phosphatase activity
MASE_08755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MASE_08780	COG1185	polyribonucleotide nucleotidyltransferase activity
MASE_08845	COG1228	amidohydrolase
MASE_08970	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
MASE_08975	COG1196	nuclear chromosome segregation
MASE_08985	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MASE_09000	COG1132	(ABC) transporter
MASE_09005	COG1663	tetraacyldisaccharide 4'-kinase activity
MASE_09045	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MASE_09050	COG0435	Glutathione S-transferase
MASE_09055	COG1741	Belongs to the pirin family
MASE_09080	COG0372	Belongs to the citrate synthase family
MASE_09085	COG2009	succinate dehydrogenase
MASE_09090	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MASE_09095	COG1053	succinate dehydrogenase
MASE_09100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MASE_09105	COG0567	Dehydrogenase, E1 component
MASE_09110	COG0508	dehydrogenase complex catalyzes the overall conversion of
MASE_09145	COG4667	esterase of the alpha-beta hydrolase superfamily
MASE_09165	COG0366	Alpha amylase catalytic
MASE_09175	COG1874	Beta-galactosidase
MASE_09175	COG0366	Alpha amylase catalytic
MASE_09180	COG1609	Transcriptional regulator
MASE_09190	COG1028	Short-chain dehydrogenase reductase Sdr
MASE_09195	COG2267	carboxylic ester hydrolase activity
MASE_09205	COG0616	signal peptide processing
MASE_09220	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MASE_09225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MASE_09230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MASE_09235	COG0386	Belongs to the glutathione peroxidase family
MASE_09240	COG2084	Dehydrogenase
MASE_09250	COG1960	acyl-CoA dehydrogenase activity
MASE_09255	COG1024	Enoyl-CoA hydratase
MASE_09260	COG2226	methyltransferase
MASE_09265	COG0513	Belongs to the DEAD box helicase family
MASE_09270	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MASE_09270	COG3264	Mechanosensitive ion channel
MASE_09290	COG2202	Pas domain
MASE_09290	COG2200	EAL domain
MASE_09290	COG2199	diguanylate cyclase activity
MASE_09315	COG0730	response to heat
MASE_09335	COG4191	Histidine kinase
MASE_09345	COG0417	DNA replication proofreading
MASE_09355	COG0318	PFAM AMP-dependent synthetase and ligase
MASE_09360	COG3083	sulfuric ester hydrolase activity
MASE_09365	COG3082	Protein of unknown function (DUF1414)
MASE_09370	COG3081	Nucleoid-associated protein
MASE_09380	COG0739	heme binding
MASE_09380	COG1196	nuclear chromosome segregation
MASE_09380	COG0741	lytic transglycosylase activity
MASE_09400	COG3275	phosphorelay sensor kinase activity
MASE_09405	COG3279	Response regulator of the LytR AlgR family
MASE_09410	COG0205	6-phosphofructokinase activity
MASE_09425	COG2205	protein histidine kinase activity
MASE_09425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MASE_09465	COG0513	Belongs to the DEAD box helicase family
MASE_09475	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MASE_09480	COG0583	DNA-binding transcription factor activity
MASE_09500	COG1760	l-serine dehydratase
MASE_09520	COG1322	Protein conserved in bacteria
MASE_09525	COG1404	Belongs to the peptidase S8 family
MASE_09530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MASE_09535	COG0022	dehydrogenase e1 component
MASE_09545	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MASE_09550	COG0515	serine threonine protein kinase
MASE_09555	COG1946	Acyl-CoA thioesterase
MASE_09565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MASE_09575	COG1956	GAF domain-containing protein
MASE_09590	COG0793	Belongs to the peptidase S41A family
MASE_09595	COG0733	neurotransmitter:sodium symporter activity
MASE_09605	COG0308	aminopeptidase N
MASE_09635	COG2902	Dehydrogenase
MASE_09640	COG0167	dihydroorotate dehydrogenase activity
MASE_09665	COG3130	regulation of translation
MASE_09670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MASE_09680	COG0415	Belongs to the DNA photolyase family
MASE_09685	COG0415	Belongs to the DNA photolyase family
MASE_09690	COG0415	Belongs to the DNA photolyase family
MASE_09695	COG3046	protein related to deoxyribodipyrimidine photolyase
MASE_09720	COG0318	PFAM AMP-dependent synthetase and ligase
MASE_09730	COG1082	Xylose isomerase domain protein TIM barrel
MASE_09780	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MASE_09785	COG0589	response to stress
MASE_09795	COG0069	glutamate synthase activity
MASE_09810	COG2193	ferroxidase activity
MASE_09820	COG3278	Belongs to the heme-copper respiratory oxidase family
MASE_09835	COG2010	Cytochrome c
MASE_09865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MASE_09870	COG0589	response to stress
MASE_09880	COG1752	Esterase of the alpha-beta hydrolase superfamily
MASE_09900	COG1280	lysine exporter protein (LysE YggA)
MASE_09905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MASE_09910	COG2897	thiosulfate sulfurtransferase activity
MASE_09915	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MASE_09930	COG0322	excinuclease ABC activity
MASE_09935	COG2197	response regulator
MASE_09940	COG1741	Belongs to the pirin family
MASE_09950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MASE_09960	COG3384	dioxygenase
MASE_09965	COG2259	Doxx family
MASE_09970	COG0583	DNA-binding transcription factor activity
MASE_09980	COG0670	Belongs to the BI1 family
MASE_09985	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MASE_10000	COG2920	part of a sulfur-relay system
MASE_10030	COG4771	TonB-dependent receptor
MASE_10045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MASE_10050	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MASE_10055	COG0531	amino acid
MASE_10055	COG1674	ftsk spoiiie
MASE_10065	COG0686	Belongs to the AlaDH PNT family
MASE_10070	COG0284	orotidine-5'-phosphate decarboxylase activity
MASE_10075	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MASE_10090	COG0776	regulation of translation
MASE_10095	COG0539	negative regulation of cytoplasmic translation
MASE_10100	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MASE_10105	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MASE_10110	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MASE_10120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MASE_10125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MASE_10130	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MASE_10135	COG0633	Ferredoxin
MASE_10140	COG4221	oxidoreductase activity
MASE_10165	COG3706	GGDEF domain
MASE_10165	COG0745	RESPONSE REGULATOR receiver
MASE_10180	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
MASE_10185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MASE_10195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MASE_10205	COG4783	chaperone-mediated protein folding
MASE_10210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MASE_10215	COG1393	Belongs to the ArsC family
MASE_10250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MASE_10260	COG1960	acyl-CoA dehydrogenase activity
MASE_10285	COG0572	uridine kinase
MASE_10290	COG3769	mannosylglycerate metabolic process
MASE_10295	COG1215	transferase activity, transferring glycosyl groups
MASE_10310	COG0303	'Molybdopterin
MASE_10315	COG0534	Mate efflux family protein
MASE_10335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MASE_10385	COG2801	Transposase and inactivated derivatives
MASE_10395	COG3011	Protein conserved in bacteria
MASE_10440	COG0405	Gamma-glutamyltransferase
MASE_10445	COG1024	Enoyl-CoA hydratase
MASE_10505	COG1671	Belongs to the UPF0178 family
MASE_10510	COG1028	Short-chain dehydrogenase reductase Sdr
MASE_10515	COG1028	Short-chain dehydrogenase reductase Sdr
MASE_10520	COG1960	acyl-CoA dehydrogenase activity
MASE_10525	COG0662	Cupin 2, conserved barrel domain protein
MASE_10525	COG2207	Transcriptional regulator
MASE_10540	COG1505	serine-type exopeptidase activity
MASE_10585	COG0596	Alpha beta hydrolase
MASE_10595	COG0716	FMN binding
MASE_10605	COG0735	belongs to the Fur family
MASE_10615	COG1984	allophanate hydrolase subunit 2
MASE_10620	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MASE_10625	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MASE_10630	COG2996	Protein conserved in bacteria
MASE_10635	COG1765	OsmC-like protein
MASE_10640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MASE_10685	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
MASE_10690	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MASE_10715	COG0653	protein targeting
MASE_10720	COG0366	Alpha amylase catalytic
MASE_10725	COG0604	alcohol dehydrogenase
MASE_10735	COG1960	acyl-CoA dehydrogenase activity
MASE_10745	COG4771	TonB-dependent receptor
MASE_10765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MASE_10770	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MASE_10790	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MASE_10795	COG0315	cyclic pyranopterin monophosphate synthase activity
MASE_10800	COG0521	Mo-molybdopterin cofactor biosynthetic process
MASE_10805	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MASE_10845	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MASE_10855	COG3268	Saccharopine dehydrogenase
MASE_10860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MASE_10875	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MASE_10880	COG4771	TonB-dependent receptor
MASE_10925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MASE_10935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MASE_10940	COG1074	ATP-dependent DNA helicase activity
MASE_10945	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MASE_10955	COG1022	Amp-dependent synthetase and ligase
MASE_10985	COG0583	DNA-binding transcription factor activity
MASE_11005	COG0640	Transcriptional regulator
MASE_11025	COG2204	response regulator
MASE_11035	COG4251	negative regulation of phosphorylation
MASE_11040	COG0784	Response regulator, receiver
MASE_11045	COG0784	Response regulator, receiver
MASE_11045	COG2205	protein histidine kinase activity
MASE_11105	COG3139	Protein of unknown function (DUF1315)
MASE_11115	COG1115	amino acid carrier protein
MASE_11120	COG2866	Carboxypeptidase
MASE_11140	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MASE_11150	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MASE_11155	COG1640	4-alpha-glucanotransferase
MASE_11165	COG0676	glucose-6-phosphate 1-epimerase activity
MASE_11170	COG0800	Aldolase
MASE_11180	COG0129	dihydroxy-acid dehydratase activity
MASE_11190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MASE_11195	COG1737	Transcriptional regulator
MASE_11200	COG0469	pyruvate kinase activity
MASE_11205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MASE_11225	COG2823	Periplasmic or secreted lipoprotein
MASE_11250	COG3665	Urea carboxylase-associated protein
MASE_11270	COG1028	Short-chain dehydrogenase reductase Sdr
MASE_11275	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MASE_11285	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MASE_11300	COG2721	sulfolactate sulfo-lyase activity
MASE_11305	COG1904	glucuronate isomerase
MASE_11310	COG0246	Mannitol dehydrogenase
MASE_11315	COG0800	Aldolase
MASE_11320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MASE_11325	COG2755	lipolytic protein G-D-S-L family
MASE_11340	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MASE_11380	COG2356	endonuclease I
MASE_11405	COG0583	DNA-binding transcription factor activity
MASE_11415	COG1979	alcohol dehydrogenase
MASE_11420	COG1902	pentaerythritol trinitrate reductase activity
MASE_11425	COG2203	Gaf domain
MASE_11425	COG3706	GGDEF domain
MASE_11425	COG5001	Diguanylate cyclase
MASE_11425	COG4251	negative regulation of phosphorylation
MASE_11435	COG0753	catalase activity
MASE_11440	COG0784	Response regulator, receiver
MASE_11440	COG3437	response regulator, receiver
MASE_11445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MASE_11445	COG4191	Histidine kinase
MASE_11485	COG0471	metal ion transport
MASE_11500	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MASE_11500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MASE_11505	COG0668	transmembrane transport
MASE_11510	COG2226	methyltransferase
MASE_11515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MASE_11545	COG3138	arginine N-succinyltransferase
MASE_11550	COG0215	cysteine-tRNA ligase activity
MASE_11555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MASE_11560	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MASE_11570	COG2268	Band 7 protein
MASE_11575	COG0583	DNA-binding transcription factor activity
MASE_11580	COG1028	Short-chain dehydrogenase reductase Sdr
MASE_11595	COG1733	regulation of RNA biosynthetic process
MASE_11600	COG0604	alcohol dehydrogenase
MASE_11605	COG0861	Integral membrane protein TerC family
MASE_11610	COG1063	alcohol dehydrogenase
MASE_11615	COG0583	DNA-binding transcription factor activity
MASE_11650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MASE_11655	COG1286	toxin biosynthetic process
MASE_11660	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
MASE_11665	COG0285	dihydrofolate synthase activity
MASE_11690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MASE_11710	COG3609	addiction module antidote protein, CC2985 family
MASE_11715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MASE_11735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MASE_11735	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MASE_11780	COG0789	Transcriptional regulator
MASE_11790	COG1028	Short-chain dehydrogenase reductase Sdr
MASE_11795	COG1119	ATPase activity
MASE_11805	COG0523	cobalamin synthesis protein
MASE_11810	COG1917	Cupin 2, conserved barrel domain protein
MASE_11810	COG4977	sequence-specific DNA binding
MASE_11815	COG1335	isochorismatase
MASE_11825	COG2031	fatty acid transporter
MASE_11830	COG2205	protein histidine kinase activity
MASE_11830	COG0784	Response regulator, receiver
MASE_11830	COG5002	protein histidine kinase activity
MASE_11835	COG0612	Peptidase, M16
MASE_11850	COG3101	peptidyl-lysine hydroxylation
MASE_11875	COG0446	pyridine nucleotide-disulphide oxidoreductase
MASE_11875	COG1902	pentaerythritol trinitrate reductase activity
MASE_11900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MASE_11910	COG4399	Belongs to the UPF0754 family
MASE_11940	COG2186	Transcriptional regulator
MASE_11950	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MASE_11955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MASE_11960	COG2983	Belongs to the UPF0260 family
MASE_11965	COG0179	Fumarylacetoacetate (FAA) hydrolase
MASE_11980	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MASE_11985	COG0318	PFAM AMP-dependent synthetase and ligase
MASE_11990	COG2267	carboxylic ester hydrolase activity
MASE_12005	COG1214	PFAM Peptidase M22, glycoprotease
MASE_12010	COG1199	ATP-dependent helicase activity
MASE_12095	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MASE_12100	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MASE_12105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MASE_12110	COG0131	Imidazoleglycerol-phosphate dehydratase
MASE_12110	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MASE_12115	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MASE_12130	COG0140	phosphoribosyl-ATP diphosphatase activity
MASE_12130	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MASE_12145	COG2116	formate transmembrane transporter activity
MASE_12150	COG0612	Peptidase, M16
MASE_12180	COG0326	Molecular chaperone. Has ATPase activity
MASE_12185	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MASE_12210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MASE_12215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MASE_12225	COG3220	belongs to the UPF0276 family
MASE_12235	COG3710	Transcriptional regulator
MASE_12245	COG4251	negative regulation of phosphorylation
MASE_12245	COG3706	GGDEF domain
MASE_12245	COG5001	Diguanylate cyclase
MASE_12245	COG2203	Gaf domain
MASE_12255	COG1183	phosphatidylcholine synthase activity
MASE_12275	COG0277	FAD linked oxidase domain protein
MASE_12280	COG1620	l-lactate permease
MASE_12300	COG0542	response to heat
MASE_12315	COG0564	pseudouridine synthase activity
MASE_12330	COG1595	DNA-templated transcription, initiation
MASE_12345	COG4221	oxidoreductase activity
MASE_12360	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MASE_12370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MASE_12380	COG0142	geranyltranstransferase activity
MASE_12395	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MASE_12400	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MASE_12410	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MASE_12425	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MASE_12425	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MASE_12445	COG0488	(ABC) transporter
MASE_12455	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MASE_12465	COG0560	Phosphoserine phosphatase
MASE_12475	COG0084	hydrolase, TatD family'
MASE_12490	COG0571	ribonuclease III activity
MASE_12495	COG0681	Belongs to the peptidase S26 family
MASE_12520	COG1595	DNA-templated transcription, initiation
MASE_12525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MASE_12540	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MASE_12620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MASE_12625	COG1047	Peptidyl-prolyl cis-trans
MASE_12635	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MASE_12640	COG0196	riboflavin kinase activity
MASE_12645	COG0728	peptidoglycan biosynthetic process
MASE_12650	COG0268	Binds directly to 16S ribosomal RNA
MASE_12665	COG1028	Short-chain dehydrogenase reductase Sdr
MASE_12670	COG0385	Bile acid
MASE_12675	COG0583	DNA-binding transcription factor activity
MASE_12700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MASE_12705	COG0776	regulation of translation
MASE_12710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MASE_12715	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MASE_12720	COG0740	serine-type endopeptidase activity
MASE_12725	COG0544	peptidyl-prolyl cis-trans isomerase activity
MASE_12745	COG1720	tRNA m6t6A37 methyltransferase activity
MASE_12755	COG1234	tRNA 3'-trailer cleavage
MASE_12765	COG0123	including yeast histone deacetylase and acetoin utilization protein
MASE_12780	COG0516	GMP reductase activity
MASE_12780	COG0517	IMP dehydrogenase activity
MASE_12785	COG1570	exodeoxyribonuclease VII activity
MASE_12810	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MASE_12815	COG2976	Protein conserved in bacteria
MASE_12835	COG3063	Type IV pilus biogenesis stability protein PilW
MASE_12855	COG2166	iron-sulfur cluster assembly
MASE_12870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MASE_12875	COG0719	Fe-S assembly protein
MASE_12880	COG0396	ATPase activity
MASE_12885	COG0719	Fe-S assembly protein
MASE_12890	COG1104	cysteine desulfurase activity
MASE_12895	COG1959	2 iron, 2 sulfur cluster binding
MASE_12905	COG2072	flavoprotein involved in K transport
MASE_12910	COG1045	serine acetyltransferase
MASE_12915	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MASE_12920	COG0483	inositol monophosphate 1-phosphatase activity
MASE_12930	COG3279	Response regulator of the LytR AlgR family
MASE_12935	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MASE_12940	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MASE_12945	COG1862	Preprotein translocase
MASE_12950	COG0343	queuine tRNA-ribosyltransferase activity
MASE_12970	COG1842	Phage shock protein A
MASE_12975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MASE_12995	COG0754	glutathionylspermidine amidase activity
MASE_13025	COG2066	Belongs to the glutaminase family
MASE_13030	COG1785	Belongs to the alkaline phosphatase family
MASE_13135	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MASE_13155	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MASE_13155	COG2755	lipolytic protein G-D-S-L family
MASE_13165	COG0367	asparagine synthase
MASE_13210	COG0367	asparagine synthase
MASE_13245	COG0489	protein tyrosine kinase activity
MASE_13265	COG2827	Endonuclease containing a URI domain
MASE_13285	COG1560	Kdo2-lipid A biosynthetic process
MASE_13300	COG1960	acyl-CoA dehydrogenase activity
MASE_13320	COG1435	thymidine kinase activity
MASE_13335	COG1609	Transcriptional regulator
MASE_13340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MASE_13365	COG1082	Xylose isomerase domain protein TIM barrel
MASE_13375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MASE_13420	COG1012	belongs to the aldehyde dehydrogenase family
MASE_13440	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
MASE_13445	COG0789	Transcriptional regulator
MASE_13480	COG1960	acyl-CoA dehydrogenase activity
MASE_13545	COG2080	2 iron, 2 sulfur cluster binding
MASE_13550	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MASE_13555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MASE_13565	COG0601	transmembrane transport
MASE_13575	COG4172	Belongs to the ABC transporter superfamily
MASE_13580	COG1028	Short-chain dehydrogenase reductase Sdr
MASE_13595	COG0693	protein deglycase activity
MASE_13605	COG1295	ribonuclease BN
MASE_13625	COG3279	Response regulator of the LytR AlgR family
MASE_13630	COG2207	Transcriptional regulator
MASE_13635	COG1073	alpha beta
MASE_13640	COG1073	alpha beta
MASE_13695	COG4681	YaeQ
MASE_13730	COG0339	signal peptide processing
MASE_13740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MASE_13770	COG0514	ATP-dependent DNA helicase (RecQ)
MASE_13795	COG4251	negative regulation of phosphorylation
MASE_13800	COG2133	pyrroloquinoline quinone binding
MASE_13845	COG0738	Major facilitator superfamily
MASE_13850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MASE_13860	COG2971	BadF BadG BcrA BcrD
MASE_13885	COG0583	DNA-binding transcription factor activity
MASE_13910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MASE_13915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MASE_13920	COG0006	proline dipeptidase activity
MASE_13935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MASE_13945	COG2205	protein histidine kinase activity
MASE_13955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MASE_13960	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MASE_13965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MASE_13985	COG3313	Fe-S protein
MASE_14015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MASE_14020	COG0508	dehydrogenase complex catalyzes the overall conversion of
MASE_14025	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MASE_14030	COG2186	Transcriptional regulator
MASE_14045	COG3577	Aspartyl protease
MASE_14050	COG0157	Belongs to the NadC ModD family
MASE_14055	COG4969	Belongs to the N-Me-Phe pilin family
MASE_14060	COG1459	type II secretion system
MASE_14065	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MASE_14085	COG3608	succinylglutamate desuccinylase aspartoacylase
MASE_14090	COG0840	transmembrane signaling receptor activity
MASE_14095	COG4566	intracellular signal transduction
MASE_14100	COG1192	Involved in chromosome partitioning
MASE_14110	COG2198	Histidine kinase
MASE_14110	COG0643	Histidine kinase
MASE_14115	COG0745	RESPONSE REGULATOR receiver
MASE_14120	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MASE_14130	COG2201	protein-glutamate methylesterase activity
MASE_14135	COG0835	chemotaxis
MASE_14140	COG0840	transmembrane signaling receptor activity
MASE_14145	COG0494	nUDIX hydrolase
MASE_14155	COG0739	heme binding
MASE_14160	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MASE_14165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MASE_14170	COG0849	cell division
MASE_14175	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MASE_14180	COG1181	Belongs to the D-alanine--D-alanine ligase family
MASE_14195	COG0772	Belongs to the SEDS family
MASE_14200	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MASE_14210	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MASE_14215	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MASE_14220	COG0768	penicillin binding
MASE_14225	COG3116	cell division
MASE_14235	COG2001	Belongs to the MraZ family
MASE_14255	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MASE_14260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MASE_14280	COG0678	peroxiredoxin activity
MASE_14280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MASE_14295	COG3706	GGDEF domain
MASE_14305	COG2204	response regulator
MASE_14330	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MASE_14330	COG0678	peroxiredoxin activity
MASE_14345	COG3706	GGDEF domain
MASE_14355	COG2204	response regulator
MASE_14380	COG0668	transmembrane transport
MASE_14385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MASE_14390	COG0189	ligase activity
MASE_14395	COG1678	Uncharacterized ACR, COG1678
MASE_14400	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MASE_14425	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MASE_14430	COG0762	integral membrane protein
MASE_14440	COG1902	pentaerythritol trinitrate reductase activity
MASE_14440	COG0446	pyridine nucleotide-disulphide oxidoreductase
MASE_14465	COG1764	response to oxidative stress
MASE_14470	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MASE_14480	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MASE_14490	COG2814	Major facilitator Superfamily
MASE_14495	COG0724	RNA recognition motif
MASE_14530	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MASE_14540	COG0083	homoserine kinase activity
MASE_14555	COG0583	DNA-binding transcription factor activity
MASE_14570	COG2197	response regulator
MASE_14575	COG4585	Histidine kinase
MASE_14590	COG0640	Transcriptional regulator
MASE_14600	COG0431	NADPH-dependent FMN reductase
MASE_14605	COG0798	PFAM Bile acid sodium symporter
MASE_14610	COG2201	protein-glutamate methylesterase activity
MASE_14615	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
MASE_14625	COG5002	protein histidine kinase activity
MASE_14625	COG3850	Histidine kinase
MASE_14645	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MASE_14655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MASE_14680	COG1748	Saccharopine dehydrogenase
MASE_14700	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MASE_14705	COG3107	peptidoglycan biosynthetic process
MASE_14710	COG0792	nuclease activity
MASE_14725	COG2823	Periplasmic or secreted lipoprotein
MASE_14745	COG4585	Histidine kinase
MASE_14750	COG2197	response regulator
MASE_14765	COG4771	TonB-dependent receptor
MASE_14775	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MASE_14780	COG0372	Belongs to the citrate synthase family
MASE_14785	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MASE_14790	COG2828	Protein conserved in bacteria
MASE_14795	COG2199	diguanylate cyclase activity
MASE_14795	COG2203	Gaf domain
MASE_14815	COG2198	Histidine kinase
MASE_14815	COG0784	Response regulator, receiver
MASE_14815	COG5002	protein histidine kinase activity
MASE_14825	COG0069	glutamate synthase activity
MASE_14825	COG0070	glutamate synthase
MASE_14825	COG0067	glutamate synthase
MASE_14830	COG0493	'glutamate synthase
MASE_14850	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MASE_14855	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MASE_14860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MASE_14880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MASE_14885	COG5507	3-demethylubiquinone-9 3-methyltransferase
MASE_14910	COG0739	heme binding
MASE_14910	COG0741	lytic transglycosylase activity
MASE_14910	COG1196	nuclear chromosome segregation
MASE_14915	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MASE_14925	COG0738	Major facilitator superfamily
MASE_14935	COG1902	pentaerythritol trinitrate reductase activity
MASE_14950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MASE_14955	COG0625	glutathione transferase activity
MASE_14975	COG2894	cell division
MASE_14980	COG0850	regulation of cytokinetic process
MASE_15030	COG1914	H( )-stimulated, divalent metal cation uptake system
MASE_15050	COG0174	glutamine synthetase
MASE_15060	COG3852	Histidine kinase
MASE_15065	COG2204	response regulator
MASE_15070	COG3437	response regulator, receiver
MASE_15075	COG0204	Acyl-transferase
MASE_15090	COG3706	GGDEF domain
MASE_15115	COG0525	valine-tRNA ligase activity
MASE_15120	COG2927	DNA polymerase III (CHI subunit)
MASE_15125	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MASE_15130	COG0795	lipopolysaccharide-transporting ATPase activity
MASE_15135	COG0795	lipopolysaccharide-transporting ATPase activity
MASE_15185	COG1401	restriction endodeoxyribonuclease activity
MASE_15185	COG1401	restriction endodeoxyribonuclease activity
MASE_15230	COG0673	inositol 2-dehydrogenase activity
MASE_15235	COG0784	Response regulator, receiver
MASE_15235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MASE_15235	COG2198	Histidine kinase
MASE_15235	COG2205	protein histidine kinase activity
MASE_15240	COG0628	permease
MASE_15260	COG1858	cytochrome C peroxidase
MASE_15300	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MASE_15305	COG0697	spore germination
MASE_15330	COG4771	TonB-dependent receptor
MASE_15340	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MASE_15365	COG2080	2 iron, 2 sulfur cluster binding
MASE_15380	COG1609	Transcriptional regulator
MASE_15410	COG1971	Probably functions as a manganese efflux pump
MASE_15440	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MASE_15445	COG3706	GGDEF domain
MASE_15450	COG0679	Auxin Efflux Carrier
MASE_15485	COG1131	(ABC) transporter
MASE_15500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MASE_15550	COG2205	protein histidine kinase activity
MASE_15560	COG3901	Regulator of nitric oxide reductase transcription
MASE_15560	COG0348	domain, Protein
MASE_15570	COG2197	response regulator
MASE_15610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MASE_15615	COG0583	DNA-binding transcription factor activity
MASE_15620	COG1304	FMN binding
MASE_15625	COG0277	FAD linked oxidase domain protein
MASE_15635	COG1462	curli production assembly transport component CsgG
MASE_15665	COG2197	response regulator
MASE_15680	COG0513	Belongs to the DEAD box helicase family
MASE_15685	COG3264	Mechanosensitive ion channel
MASE_15685	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MASE_15705	COG2199	diguanylate cyclase activity
MASE_15705	COG2200	EAL domain
MASE_15705	COG2202	Pas domain
MASE_15730	COG0730	response to heat
MASE_15750	COG4191	Histidine kinase
MASE_15760	COG0417	DNA replication proofreading
MASE_15770	COG0318	PFAM AMP-dependent synthetase and ligase
MASE_15800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MASE_15810	COG1573	uracil-dna glycosylase
MASE_15815	COG3300	MHYT domain
MASE_15815	COG5001	Diguanylate cyclase
MASE_15835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MASE_15855	COG1983	PspC domain protein
MASE_15860	COG1842	Phage shock protein A
MASE_15870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MASE_15880	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MASE_15880	COG2885	chlorophyll binding
MASE_15885	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MASE_15895	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MASE_15900	COG0204	Acyl-transferase
MASE_15905	COG0204	Acyl-transferase
MASE_15910	COG0668	transmembrane transport
MASE_15925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MASE_15930	COG0733	neurotransmitter:sodium symporter activity
MASE_15945	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MASE_15960	COG0716	FMN binding
MASE_15970	COG0848	biopolymer transport protein
MASE_15980	COG0457	Tetratricopeptide repeat
MASE_15985	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MASE_16010	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MASE_16015	COG0702	epimerase
MASE_16030	COG5002	protein histidine kinase activity
MASE_16030	COG5001	Diguanylate cyclase
MASE_16040	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MASE_16050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MASE_16060	COG0583	DNA-binding transcription factor activity
MASE_16065	COG0121	glutamine amidotransferase
MASE_16080	COG4682	membrane
MASE_16100	COG1953	Uracil, thiamine, allantoin
MASE_16105	COG4771	TonB-dependent receptor
MASE_16115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MASE_16120	COG0778	Nitroreductase
MASE_16125	COG0596	Alpha beta hydrolase
MASE_16130	COG0251	oxidation-reduction process
MASE_16135	COG1335	isochorismatase
MASE_16140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MASE_16145	COG1309	transcriptional regulator
MASE_16160	COG4628	conserved protein (DUF2132)
MASE_16170	COG3265	gluconokinase activity
MASE_16175	COG1609	Transcriptional regulator
MASE_16180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MASE_16190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MASE_16200	COG1477	protein flavinylation
MASE_16205	COG2871	sodium ion transport
MASE_16210	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MASE_16215	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MASE_16220	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MASE_16225	COG1805	sodium ion transport
MASE_16230	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MASE_16235	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MASE_16240	COG0545	Peptidyl-prolyl cis-trans isomerase
MASE_16245	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MASE_16250	COG0039	L-malate dehydrogenase activity
MASE_16255	COG1438	arginine binding
MASE_16280	COG0572	uridine kinase
MASE_16285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MASE_16300	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MASE_16310	COG3706	GGDEF domain
MASE_16310	COG0745	RESPONSE REGULATOR receiver
MASE_16350	COG0189	ligase activity
MASE_16360	COG0189	ligase activity
MASE_16360	COG4067	protein conserved in archaea
MASE_16375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MASE_16385	COG1283	sodium-dependent phosphate transmembrane transporter activity
MASE_16390	COG0667	Aldo Keto reductase
MASE_16450	COG0753	catalase activity
MASE_16475	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MASE_16485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MASE_16525	COG0583	DNA-binding transcription factor activity
MASE_16550	COG1091	dTDP-4-dehydrorhamnose reductase activity
MASE_16585	COG1051	belongs to the nudix hydrolase family
MASE_16590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MASE_16610	COG2801	Transposase and inactivated derivatives
MASE_16660	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MASE_16680	COG0517	IMP dehydrogenase activity
MASE_16680	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MASE_16730	COG0110	maltose O-acetyltransferase activity
MASE_16780	COG0438	transferase activity, transferring glycosyl groups
MASE_16780	COG1216	Glycosyl transferase, family 2
MASE_16785	COG0662	Cupin 2, conserved barrel domain protein
MASE_16785	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MASE_16795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MASE_16805	COG0202	RNA polymerase activity
MASE_16855	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MASE_16890	COG5002	protein histidine kinase activity
MASE_16890	COG0784	Response regulator, receiver
MASE_16910	COG0557	exoribonuclease II activity
MASE_16930	COG4771	TonB-dependent receptor
MASE_16945	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MASE_16970	COG2234	aminopeptidase activity
MASE_16980	COG4251	negative regulation of phosphorylation
MASE_16990	COG1271	oxidase subunit
MASE_16995	COG1294	oxidase, subunit
MASE_17010	COG1522	sequence-specific DNA binding
MASE_17020	COG1278	Cold shock
MASE_17025	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MASE_17035	COG2226	methyltransferase
MASE_17045	COG0339	signal peptide processing
MASE_17050	COG2201	protein-glutamate methylesterase activity
MASE_17070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MASE_17075	COG0243	molybdopterin cofactor binding
MASE_17090	COG1506	peptidase
MASE_17090	COG4946	Tricorn protease homolog
MASE_17090	COG0823	Involved in the tonB-independent uptake of proteins
MASE_17140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MASE_17150	COG2197	response regulator
MASE_17180	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MASE_17185	COG1278	Cold shock
MASE_17200	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MASE_17205	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MASE_17225	COG0281	malic enzyme
MASE_17235	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MASE_17265	COG0456	acetyltransferase
MASE_17275	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MASE_17280	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MASE_17285	COG2177	Part of the ABC transporter FtsEX involved in
MASE_17290	COG2884	Cell division ATP-binding protein ftsE
MASE_17295	COG0552	protein localization to endoplasmic reticulum
MASE_17300	COG0742	ribosomal rna small subunit methyltransferase
MASE_17310	COG2095	MarC family integral membrane protein
MASE_17320	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MASE_17330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MASE_17335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MASE_17340	COG0617	tRNA 3'-terminal CCA addition
MASE_17345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MASE_17360	COG0076	glutamate decarboxylase activity
MASE_17375	COG0842	Transport permease protein
MASE_17380	COG1131	(ABC) transporter
MASE_17385	COG0745	RESPONSE REGULATOR receiver
MASE_17390	COG2205	protein histidine kinase activity
MASE_17410	COG1253	flavin adenine dinucleotide binding
MASE_17415	COG0701	Predicted permease
MASE_17420	COG1966	Carbon starvation protein
MASE_17465	COG0848	biopolymer transport protein
MASE_17475	COG0811	peptide transport
MASE_17495	COG3128	pkhd-type hydroxylase
MASE_17520	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MASE_17525	COG0049	tRNA binding
MASE_17530	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MASE_17535	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MASE_17540	COG0085	RNA polymerase activity
MASE_17550	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MASE_17555	COG0081	regulation of translation
MASE_17560	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MASE_17565	COG0250	Participates in transcription elongation, termination and antitermination
MASE_17570	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MASE_17575	COG1132	(ABC) transporter
MASE_17580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MASE_17585	COG3590	peptidase
MASE_17600	COG0513	Belongs to the DEAD box helicase family
MASE_17610	COG0418	dihydroorotase activity
MASE_17615	COG3040	lipid binding
MASE_17620	COG4989	oxidoreductase activity
MASE_17625	COG0346	lactoylglutathione lyase activity
MASE_17630	COG0668	transmembrane transport
MASE_17650	COG0302	gtp cyclohydrolase
MASE_17660	COG2957	Belongs to the agmatine deiminase family
MASE_17665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MASE_17675	COG1201	RNA secondary structure unwinding
MASE_17680	COG2311	Membrane
MASE_17695	COG1793	dna ligase
MASE_17700	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MASE_17705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MASE_17730	COG0625	glutathione transferase activity
MASE_17735	COG0625	glutathione transferase activity
MASE_17745	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MASE_17750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MASE_17760	COG1012	belongs to the aldehyde dehydrogenase family
MASE_17765	COG0028	Belongs to the TPP enzyme family
MASE_17780	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MASE_17785	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MASE_17790	COG0330	HflC and HflK could
MASE_17795	COG0330	HflC and HflK could
MASE_17800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MASE_17805	COG1923	regulation of RNA biosynthetic process
MASE_17810	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MASE_17825	COG0802	atpase or kinase
MASE_17830	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MASE_17830	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MASE_17835	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MASE_17845	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MASE_17850	COG2816	NAD+ diphosphatase activity
MASE_17855	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
MASE_17860	COG0735	belongs to the Fur family
MASE_17870	COG0432	Pfam Uncharacterised protein family UPF0047
MASE_17880	COG0305	Participates in initiation and elongation during chromosome replication
MASE_17905	COG2258	MOSC domain
MASE_17975	COG0840	transmembrane signaling receptor activity
MASE_17980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MASE_17980	COG4191	Histidine kinase
MASE_17985	COG0840	transmembrane signaling receptor activity
MASE_18000	COG2855	membrane
MASE_18005	COG2175	clavaminate synthase activity
MASE_18010	COG0656	L-ascorbic acid biosynthetic process
MASE_18030	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MASE_18035	COG4771	TonB-dependent receptor
MASE_18055	COG3706	GGDEF domain
MASE_18065	COG1472	Belongs to the glycosyl hydrolase 3 family
MASE_18075	COG2723	6-phospho-beta-galactosidase activity
MASE_18080	COG1609	Transcriptional regulator
MASE_18085	COG0477	Major facilitator Superfamily
MASE_18085	COG2814	Major facilitator Superfamily
MASE_18090	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MASE_18095	COG4988	ABC transporter
MASE_18100	COG4890	Cyd operon protein YbgT
MASE_18105	COG1294	oxidase, subunit
MASE_18145	COG4319	ketosteroid isomerase
MASE_18150	COG1335	isochorismatase
MASE_18155	COG2863	cytochrome
MASE_18160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MASE_18165	COG1741	Belongs to the pirin family
MASE_18185	COG1469	GTP cyclohydrolase I activity
MASE_18240	COG3237	CsbD-like
MASE_18255	COG1595	DNA-templated transcription, initiation
MASE_18285	COG0508	dehydrogenase complex catalyzes the overall conversion of
MASE_18285	COG0596	Alpha beta hydrolase
MASE_18310	COG3038	cytochrome b561
MASE_18320	COG1252	NADH dehydrogenase
MASE_18325	COG4206	TonB-dependent receptor
MASE_18340	COG0583	DNA-binding transcription factor activity
MASE_18345	COG2067	long-chain fatty acid transport protein
MASE_18350	COG2130	NADP-dependent
MASE_18355	COG4251	negative regulation of phosphorylation
MASE_18355	COG3706	GGDEF domain
MASE_18355	COG5001	Diguanylate cyclase
MASE_18355	COG2203	Gaf domain
MASE_18360	COG0784	Response regulator, receiver
MASE_18360	COG2205	protein histidine kinase activity
MASE_18370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MASE_18415	COG0789	Transcriptional regulator
MASE_18455	COG5290	Psort location Cytoplasmic, score
MASE_18490	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MASE_18535	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MASE_18540	COG1349	DNA-binding transcription factor activity
MASE_18545	COG0673	inositol 2-dehydrogenase activity
MASE_18560	COG0697	spore germination
MASE_18565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MASE_18580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MASE_18585	COG1166	arginine decarboxylase activity
MASE_18595	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MASE_18600	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MASE_18605	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MASE_18675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MASE_18685	COG0109	protoheme IX farnesyltransferase activity
MASE_18705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MASE_18730	COG3866	Pectate lyase
MASE_18750	COG1324	tolerance protein
MASE_18755	COG4232	protein-disulfide reductase activity
MASE_18760	COG0739	heme binding
MASE_18770	COG0511	ligase activity, forming carbon-carbon bonds
MASE_18775	COG0439	Biotin carboxylase
MASE_18820	COG0154	amidase activity
MASE_18835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MASE_18840	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MASE_18855	COG0151	Belongs to the GarS family
MASE_18870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MASE_18875	COG3954	Phosphoribulokinase
MASE_18885	COG0745	RESPONSE REGULATOR receiver
MASE_18900	COG1501	Belongs to the glycosyl hydrolase 31 family
MASE_18910	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MASE_18920	COG3031	protein transport across the cell outer membrane
MASE_18930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MASE_18935	COG1459	type II secretion system
MASE_18940	COG2165	general secretion pathway protein
MASE_18950	COG2165	general secretion pathway protein
MASE_18955	COG4795	General secretion pathway protein
MASE_18970	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
MASE_18990	COG1012	belongs to the aldehyde dehydrogenase family
MASE_19000	COG1011	Hydrolase
MASE_19005	COG0494	nUDIX hydrolase
MASE_19010	COG1218	3'(2'),5'-bisphosphate nucleotidase
MASE_19025	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
MASE_19035	COG3089	Belongs to the UPF0270 family
MASE_19040	COG0429	hydrolase of the alpha beta-hydrolase fold
MASE_19050	COG0488	(ABC) transporter
MASE_19070	COG2900	Belongs to the SlyX family
MASE_19080	COG0545	Peptidyl-prolyl cis-trans isomerase
MASE_19090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MASE_19095	COG2183	response to ionizing radiation
MASE_19125	COG1609	Transcriptional regulator
MASE_19125	COG2207	Transcriptional regulator
MASE_19130	COG2211	Major facilitator Superfamily
MASE_19160	COG3693	PFAM glycoside hydrolase, family 10
MASE_19165	COG0667	Aldo Keto reductase
MASE_19170	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MASE_19175	COG2115	Belongs to the xylose isomerase family
MASE_19180	COG1070	Carbohydrate kinase
MASE_19195	COG1472	Belongs to the glycosyl hydrolase 3 family
MASE_19200	COG0477	Major facilitator Superfamily
MASE_19245	COG0596	Alpha beta hydrolase
MASE_19250	COG1040	competence protein
MASE_19270	COG1794	racemase activity, acting on amino acids and derivatives
MASE_19285	COG0534	Mate efflux family protein
MASE_19300	COG1999	signal sequence binding
MASE_19305	COG0109	protoheme IX farnesyltransferase activity
MASE_19310	COG1612	heme a metabolic process
MASE_19335	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
MASE_19340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MASE_19345	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MASE_19360	COG3706	GGDEF domain
MASE_19375	COG0129	dihydroxy-acid dehydratase activity
MASE_19380	COG2860	membrane
MASE_19385	COG0606	chelatase, subunit chli
MASE_19390	COG0583	DNA-binding transcription factor activity
MASE_19400	COG2814	Major facilitator Superfamily
MASE_19410	COG0419	ATPase involved in DNA repair
MASE_19430	COG0463	Glycosyl transferase, family 2
MASE_19435	COG0745	RESPONSE REGULATOR receiver
MASE_19440	COG3850	Histidine kinase
MASE_19440	COG5002	protein histidine kinase activity
MASE_19445	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MASE_19475	COG2986	histidine ammonia-lyase
MASE_19490	COG2971	BadF BadG BcrA BcrD
MASE_19495	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MASE_19505	COG0488	(ABC) transporter
MASE_19535	COG0729	surface antigen
MASE_19540	COG2911	Protein conserved in bacteria
MASE_19565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MASE_19575	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MASE_19595	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MASE_19620	COG1228	amidohydrolase
MASE_19640	COG0425	Belongs to the sulfur carrier protein TusA family
MASE_19655	COG1561	YicC-like family, N-terminal region
MASE_19680	COG2211	Major facilitator Superfamily
MASE_19685	COG1609	Transcriptional regulator
MASE_19705	COG2199	diguanylate cyclase activity
MASE_19705	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MASE_19730	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MASE_19750	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MASE_19755	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MASE_19775	COG1475	DNA binding
MASE_19780	COG1192	Involved in chromosome partitioning
MASE_19805	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MASE_19810	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MASE_19820	COG0706	membrane insertase activity
MASE_19825	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MASE_19830	COG0594	ribonuclease P activity
MASE_19835	COG0230	Belongs to the bacterial ribosomal protein bL34 family