locus-tag	class	description
ALT831_00003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ALT831_00010	COG2818	Glycosylase
ALT831_00012	COG3078	GTPase activator activity
ALT831_00016	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ALT831_00016	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ALT831_00017	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ALT831_00018	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ALT831_00019	COG0569	domain protein
ALT831_00020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ALT831_00020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ALT831_00024	COG0758	DNA mediated transformation
ALT831_00027	COG0009	L-threonylcarbamoyladenylate synthase
ALT831_00028	COG0408	coproporphyrinogen oxidase activity
ALT831_00029	COG3047	cAMP biosynthetic process
ALT831_00032	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ALT831_00047	COG2234	aminopeptidase activity
ALT831_00049	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ALT831_00054	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALT831_00060	COG3642	lipopolysaccharide core region biosynthetic process
ALT831_00066	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ALT831_00069	COG3161	chorismate lyase activity
ALT831_00070	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ALT831_00072	COG0210	DNA helicase
ALT831_00080	COG0604	alcohol dehydrogenase
ALT831_00080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ALT831_00080	COG3321	synthase
ALT831_00080	COG4221	oxidoreductase activity
ALT831_00081	COG4221	oxidoreductase activity
ALT831_00082	COG0583	DNA-binding transcription factor activity
ALT831_00086	COG3321	synthase
ALT831_00086	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_00086	COG0604	alcohol dehydrogenase
ALT831_00088	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALT831_00089	COG1902	pentaerythritol trinitrate reductase activity
ALT831_00090	COG1012	belongs to the aldehyde dehydrogenase family
ALT831_00100	COG1012	belongs to the aldehyde dehydrogenase family
ALT831_00101	COG3829	transcription factor binding
ALT831_00103	COG1454	alcohol dehydrogenase
ALT831_00133	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALT831_00134	COG0842	Transport permease protein
ALT831_00134	COG1129	ABC transporter
ALT831_00135	COG0842	Transport permease protein
ALT831_00140	COG0583	DNA-binding transcription factor activity
ALT831_00142	COG3106	COG3106 Predicted ATPase
ALT831_00145	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ALT831_00148	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ALT831_00149	COG0352	thiamine-phosphate diphosphorylase activity
ALT831_00152	COG3071	HemY protein
ALT831_00153	COG2959	enzyme of heme biosynthesis
ALT831_00155	COG0181	hydroxymethylbilane synthase activity
ALT831_00158	COG0194	GDP metabolic process
ALT831_00160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ALT831_00162	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALT831_00163	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ALT831_00165	COG0678	peroxiredoxin activity
ALT831_00168	COG1178	ABC-type Fe3 transport system permease component
ALT831_00169	COG3842	ATPase activity
ALT831_00170	COG2081	HI0933 family
ALT831_00171	COG3047	cAMP biosynthetic process
ALT831_00174	COG2200	EAL domain
ALT831_00175	COG5001	Diguanylate cyclase
ALT831_00181	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALT831_00184	COG0427	acetyl-CoA hydrolase
ALT831_00185	COG0123	including yeast histone deacetylase and acetoin utilization protein
ALT831_00188	COG0840	transmembrane signaling receptor activity
ALT831_00190	COG3064	Membrane
ALT831_00192	COG5002	protein histidine kinase activity
ALT831_00192	COG5001	Diguanylate cyclase
ALT831_00195	COG0514	ATP-dependent DNA helicase (RecQ)
ALT831_00196	COG2050	protein possibly involved in aromatic compounds catabolism
ALT831_00197	COG2239	Acts as a magnesium transporter
ALT831_00198	COG2962	Rard protein
ALT831_00199	COG3706	GGDEF domain
ALT831_00200	COG0210	DNA helicase
ALT831_00202	COG3706	GGDEF domain
ALT831_00203	COG1011	Hydrolase
ALT831_00204	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ALT831_00206	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ALT831_00207	COG0019	diaminopimelate decarboxylase activity
ALT831_00214	COG0163	prenyltransferase activity
ALT831_00215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ALT831_00217	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ALT831_00224	COG1077	Cell shape determining protein MreB Mrl
ALT831_00226	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ALT831_00227	COG2814	Major facilitator Superfamily
ALT831_00228	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ALT831_00235	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ALT831_00237	COG0629	single-stranded DNA binding
ALT831_00241	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALT831_00244	COG1349	DNA-binding transcription factor activity
ALT831_00253	COG3409	Peptidoglycan-binding domain 1 protein
ALT831_00253	COG3267	Type II secretory pathway component ExeA
ALT831_00255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ALT831_00256	COG1459	type II secretion system
ALT831_00258	COG2165	general secretion pathway protein
ALT831_00259	COG2165	general secretion pathway protein
ALT831_00265	COG1077	Cell shape determining protein MreB Mrl
ALT831_00266	COG1792	Involved in formation and maintenance of cell shape
ALT831_00267	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ALT831_00269	COG1530	ribonuclease E activity
ALT831_00271	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ALT831_00272	COG0312	modulator of DNA gyrase
ALT831_00274	COG3028	Belongs to the UPF0307 family
ALT831_00275	COG0312	modulator of DNA gyrase
ALT831_00278	COG0745	RESPONSE REGULATOR receiver
ALT831_00279	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALT831_00279	COG4191	Histidine kinase
ALT831_00280	COG0297	glycogen (starch) synthase activity
ALT831_00282	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ALT831_00293	COG4974	Belongs to the 'phage' integrase family
ALT831_00311	COG0745	RESPONSE REGULATOR receiver
ALT831_00312	COG0643	Histidine kinase
ALT831_00312	COG2198	Histidine kinase
ALT831_00313	COG0835	chemotaxis
ALT831_00316	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ALT831_00319	COG0745	RESPONSE REGULATOR receiver
ALT831_00320	COG0643	Histidine kinase
ALT831_00320	COG2198	Histidine kinase
ALT831_00321	COG0835	chemotaxis
ALT831_00325	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ALT831_00335	COG0546	phosphoglycolate phosphatase activity
ALT831_00337	COG0784	Response regulator, receiver
ALT831_00337	COG2205	protein histidine kinase activity
ALT831_00340	COG1609	Transcriptional regulator
ALT831_00341	COG0673	inositol 2-dehydrogenase activity
ALT831_00343	COG2211	Major facilitator Superfamily
ALT831_00348	COG1454	alcohol dehydrogenase
ALT831_00359	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ALT831_00363	COG0089	rRNA binding
ALT831_00365	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ALT831_00367	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ALT831_00370	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ALT831_00372	COG1519	Transferase
ALT831_00380	COG0788	formyltetrahydrofolate deformylase activity
ALT831_00382	COG1643	Atp-dependent helicase
ALT831_00384	COG2951	lytic endotransglycosylase activity
ALT831_00385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ALT831_00388	COG2354	Protein conserved in bacteria
ALT831_00393	COG0004	ammonium transporteR
ALT831_00394	COG0405	Gamma-glutamyltransferase
ALT831_00395	COG2837	iron assimilation
ALT831_00398	COG0540	Belongs to the ATCase OTCase family
ALT831_00403	COG5002	protein histidine kinase activity
ALT831_00403	COG0784	Response regulator, receiver
ALT831_00403	COG2205	protein histidine kinase activity
ALT831_00406	COG3300	MHYT domain
ALT831_00406	COG5001	Diguanylate cyclase
ALT831_00408	COG1012	belongs to the aldehyde dehydrogenase family
ALT831_00410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ALT831_00412	COG0512	Glutamine amidotransferase of anthranilate synthase
ALT831_00413	COG0180	Tryptophanyl-tRNA synthetase
ALT831_00414	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ALT831_00418	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ALT831_00420	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ALT831_00427	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ALT831_00428	COG0281	malic enzyme
ALT831_00430	COG0625	glutathione transferase activity
ALT831_00433	COG0753	catalase activity
ALT831_00438	COG5001	Diguanylate cyclase
ALT831_00438	COG3300	MHYT domain
ALT831_00439	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ALT831_00439	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ALT831_00441	COG0137	argininosuccinate synthase activity
ALT831_00445	COG1803	Methylglyoxal synthase
ALT831_00447	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ALT831_00450	COG0745	RESPONSE REGULATOR receiver
ALT831_00451	COG2205	protein histidine kinase activity
ALT831_00452	COG2267	carboxylic ester hydrolase activity
ALT831_00453	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ALT831_00454	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALT831_00455	COG1136	(ABC) transporter
ALT831_00455	COG0577	efflux transmembrane transporter activity
ALT831_00458	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ALT831_00460	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ALT831_00461	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ALT831_00462	COG4942	peptidase
ALT831_00463	COG2861	carbohydrate metabolic process
ALT831_00465	COG0584	glycerophosphoryl diester phosphodiesterase
ALT831_00468	COG1162	GTPase activity
ALT831_00469	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ALT831_00476	COG0028	Belongs to the TPP enzyme family
ALT831_00480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ALT831_00481	COG0805	protein transport
ALT831_00483	COG0084	hydrolase, TatD family'
ALT831_00484	COG2203	Gaf domain
ALT831_00484	COG3706	GGDEF domain
ALT831_00484	COG4251	negative regulation of phosphorylation
ALT831_00484	COG5001	Diguanylate cyclase
ALT831_00486	COG0248	Ppx GppA phosphatase
ALT831_00487	COG0513	Belongs to the DEAD box helicase family
ALT831_00488	COG3118	belongs to the thioredoxin family
ALT831_00489	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ALT831_00490	COG1473	amidohydrolase
ALT831_00491	COG0784	Response regulator, receiver
ALT831_00491	COG2205	protein histidine kinase activity
ALT831_00492	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ALT831_00493	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ALT831_00494	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ALT831_00497	COG0783	Belongs to the Dps family
ALT831_00498	COG2133	pyrroloquinoline quinone binding
ALT831_00499	COG1506	peptidase
ALT831_00499	COG0823	Involved in the tonB-independent uptake of proteins
ALT831_00499	COG4946	Tricorn protease homolog
ALT831_00501	COG3118	belongs to the thioredoxin family
ALT831_00504	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ALT831_00506	COG1012	belongs to the aldehyde dehydrogenase family
ALT831_00511	COG1757	Na H antiporter
ALT831_00514	COG3876	Protein conserved in bacteria
ALT831_00515	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ALT831_00519	COG0346	lactoylglutathione lyase activity
ALT831_00526	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ALT831_00528	COG2824	Alkylphosphonate utilization operon protein PhnA
ALT831_00529	COG0454	-acetyltransferase
ALT831_00531	COG1742	UPF0060 membrane protein
ALT831_00546	COG0183	Belongs to the thiolase family
ALT831_00547	COG1024	Enoyl-CoA hydratase
ALT831_00547	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALT831_00548	COG0739	heme binding
ALT831_00548	COG0741	lytic transglycosylase activity
ALT831_00548	COG1196	nuclear chromosome segregation
ALT831_00549	COG0006	proline dipeptidase activity
ALT831_00551	COG0142	geranyltranstransferase activity
ALT831_00560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ALT831_00561	COG1388	LysM domain
ALT831_00561	COG4942	peptidase
ALT831_00562	COG1238	metal cluster binding
ALT831_00564	COG0585	pseudouridine synthase activity
ALT831_00565	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ALT831_00567	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ALT831_00569	COG0840	transmembrane signaling receptor activity
ALT831_00570	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ALT831_00570	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ALT831_00570	COG0506	proline dehydrogenase activity
ALT831_00573	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALT831_00580	COG0494	nUDIX hydrolase
ALT831_00581	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ALT831_00582	COG0730	response to heat
ALT831_00583	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ALT831_00584	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ALT831_00586	COG3706	GGDEF domain
ALT831_00587	COG4999	Histidine kinase
ALT831_00587	COG3437	response regulator, receiver
ALT831_00587	COG2205	protein histidine kinase activity
ALT831_00587	COG3850	Histidine kinase
ALT831_00588	COG2211	Major facilitator Superfamily
ALT831_00592	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ALT831_00595	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ALT831_00596	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALT831_00600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ALT831_00600	COG1648	precorrin-2 dehydrogenase activity
ALT831_00601	COG0513	Belongs to the DEAD box helicase family
ALT831_00605	COG1538	Outer membrane efflux protein
ALT831_00606	COG0494	nUDIX hydrolase
ALT831_00608	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ALT831_00609	COG3150	esterase
ALT831_00612	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ALT831_00616	COG1509	lysine 2,3-aminomutase activity
ALT831_00617	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ALT831_00622	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ALT831_00626	COG0271	Belongs to the BolA IbaG family
ALT831_00629	COG3707	response regulator
ALT831_00631	COG0659	secondary active sulfate transmembrane transporter activity
ALT831_00632	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ALT831_00633	COG2146	nitrite reductase [NAD(P)H] activity
ALT831_00634	COG0243	molybdopterin cofactor binding
ALT831_00635	COG1648	precorrin-2 dehydrogenase activity
ALT831_00635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ALT831_00637	COG0737	Belongs to the 5'-nucleotidase family
ALT831_00638	COG2203	Gaf domain
ALT831_00638	COG5001	Diguanylate cyclase
ALT831_00638	COG4251	negative regulation of phosphorylation
ALT831_00638	COG3706	GGDEF domain
ALT831_00641	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ALT831_00641	COG1116	anion transmembrane transporter activity
ALT831_00643	COG1116	anion transmembrane transporter activity
ALT831_00646	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ALT831_00648	COG4206	TonB-dependent receptor
ALT831_00650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ALT831_00651	COG0348	domain, Protein
ALT831_00654	COG1960	acyl-CoA dehydrogenase activity
ALT831_00655	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_00657	COG4948	Mandelate Racemase Muconate Lactonizing
ALT831_00660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALT831_00661	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALT831_00665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ALT831_00666	COG0358	DNA primase activity
ALT831_00671	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ALT831_00672	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ALT831_00675	COG0537	adenosine 5'-monophosphoramidase activity
ALT831_00678	COG3135	benzoate transporter
ALT831_00681	COG4772	TonB-dependent receptor
ALT831_00682	COG1304	FMN binding
ALT831_00685	COG0723	plastoquinol--plastocyanin reductase activity
ALT831_00687	COG3284	Transcriptional regulator
ALT831_00690	COG1012	belongs to the aldehyde dehydrogenase family
ALT831_00699	COG2201	protein-glutamate methylesterase activity
ALT831_00706	COG1396	sequence-specific DNA binding
ALT831_00707	COG2974	May be involved in recombination
ALT831_00708	COG4191	Histidine kinase
ALT831_00708	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALT831_00709	COG0745	RESPONSE REGULATOR receiver
ALT831_00710	COG5002	protein histidine kinase activity
ALT831_00716	COG0811	peptide transport
ALT831_00717	COG0811	peptide transport
ALT831_00718	COG0848	biopolymer transport protein
ALT831_00719	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ALT831_00721	COG3437	response regulator, receiver
ALT831_00725	COG2133	pyrroloquinoline quinone binding
ALT831_00726	COG1049	propionate catabolic process, 2-methylcitrate cycle
ALT831_00733	COG0527	aspartate kinase activity
ALT831_00735	COG0840	transmembrane signaling receptor activity
ALT831_00736	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ALT831_00737	COG2967	ApaG domain
ALT831_00739	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ALT831_00740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALT831_00741	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ALT831_00742	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ALT831_00744	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ALT831_00748	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ALT831_00751	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ALT831_00752	COG3956	TIGRFAM MazG family protein
ALT831_00758	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_00760	COG0318	PFAM AMP-dependent synthetase and ligase
ALT831_00762	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ALT831_00768	COG0642	Histidine kinase
ALT831_00772	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ALT831_00773	COG0723	plastoquinol--plastocyanin reductase activity
ALT831_00774	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ALT831_00775	COG2857	Cytochrome c1
ALT831_00776	COG0625	glutathione transferase activity
ALT831_00777	COG2969	positive regulation of protein catabolic process
ALT831_00780	COG0745	RESPONSE REGULATOR receiver
ALT831_00781	COG2239	Acts as a magnesium transporter
ALT831_00782	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ALT831_00786	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ALT831_00787	COG1137	ATPase activity
ALT831_00788	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ALT831_00790	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ALT831_00793	COG1127	ABC transporter
ALT831_00794	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ALT831_00795	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ALT831_00796	COG2854	intermembrane phospholipid transfer
ALT831_00798	COG5007	Belongs to the BolA IbaG family
ALT831_00800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALT831_00801	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALT831_00803	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ALT831_00809	COG2308	Evidence 4 Homologs of previously reported genes of
ALT831_00810	COG1305	Transglutaminase-like
ALT831_00818	COG4771	TonB-dependent receptor
ALT831_00819	COG0697	spore germination
ALT831_00821	COG0784	Response regulator, receiver
ALT831_00821	COG2205	protein histidine kinase activity
ALT831_00826	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ALT831_00828	COG0126	phosphoglycerate kinase activity
ALT831_00829	COG3588	fructose-bisphosphate aldolase
ALT831_00830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ALT831_00833	COG5002	protein histidine kinase activity
ALT831_00837	COG1538	Outer membrane efflux protein
ALT831_00839	COG1506	peptidase
ALT831_00839	COG4946	Tricorn protease homolog
ALT831_00839	COG0823	Involved in the tonB-independent uptake of proteins
ALT831_00840	COG0248	Ppx GppA phosphatase
ALT831_00841	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ALT831_00842	COG2716	regulation of RNA biosynthetic process
ALT831_00843	COG0573	inorganic phosphate transmembrane transporter activity
ALT831_00845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ALT831_00847	COG0306	phosphate transporter
ALT831_00849	COG0583	DNA-binding transcription factor activity
ALT831_00854	COG1272	protein, Hemolysin III
ALT831_00856	COG1846	Transcriptional regulator
ALT831_00857	COG1764	response to oxidative stress
ALT831_00860	COG1739	Uncharacterized protein family UPF0029
ALT831_00864	COG0583	DNA-binding transcription factor activity
ALT831_00865	COG4989	oxidoreductase activity
ALT831_00868	COG0420	3'-5' exonuclease activity
ALT831_00869	COG0419	ATPase involved in DNA repair
ALT831_00871	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ALT831_00875	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ALT831_00876	COG2986	histidine ammonia-lyase
ALT831_00879	COG2971	BadF BadG BcrA BcrD
ALT831_00880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ALT831_00882	COG0488	(ABC) transporter
ALT831_00888	COG0668	transmembrane transport
ALT831_00893	COG2814	Major facilitator Superfamily
ALT831_00894	COG0582	viral genome integration into host DNA
ALT831_00897	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ALT831_00911	COG1201	RNA secondary structure unwinding
ALT831_00921	COG1346	cytolysis
ALT831_00927	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ALT831_00928	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ALT831_00929	COG0513	Belongs to the DEAD box helicase family
ALT831_00933	COG3409	Peptidoglycan-binding domain 1 protein
ALT831_00933	COG3267	Type II secretory pathway component ExeA
ALT831_00938	COG0473	3-isopropylmalate dehydrogenase activity
ALT831_00939	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALT831_00943	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ALT831_00947	COG2271	Major facilitator Superfamily
ALT831_00948	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALT831_00949	COG0800	Aldolase
ALT831_00950	COG2186	Transcriptional regulator
ALT831_00957	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ALT831_00960	COG4555	ABC transporter
ALT831_00961	COG1668	transmembrane transport
ALT831_00964	COG4133	protoheme IX ABC transporter activity
ALT831_00965	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ALT831_00966	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ALT831_00967	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ALT831_00969	COG1138	Cytochrome C-type biogenesis protein
ALT831_00973	COG2853	Lipoprotein
ALT831_00974	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ALT831_00982	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ALT831_00985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ALT831_00986	COG1555	photosystem II stabilization
ALT831_00986	COG1596	polysaccharide export
ALT831_00987	COG0473	3-isopropylmalate dehydrogenase activity
ALT831_00990	COG1611	Belongs to the LOG family
ALT831_01000	COG0564	pseudouridine synthase activity
ALT831_01003	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ALT831_01004	COG0024	Methionine aminopeptidase
ALT831_01006	COG0052	Belongs to the universal ribosomal protein uS2 family
ALT831_01008	COG0528	UMP kinase activity
ALT831_01010	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ALT831_01011	COG0575	Belongs to the CDS family
ALT831_01013	COG0750	zinc metalloprotease
ALT831_01016	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ALT831_01017	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALT831_01020	COG0587	DNA-directed DNA polymerase activity
ALT831_01021	COG0825	malonyl-CoA metabolic process
ALT831_01022	COG0037	tRNA processing
ALT831_01029	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ALT831_01029	COG0047	phosphoribosylformylglycinamidine synthase activity
ALT831_01031	COG2840	Smr protein MutS2
ALT831_01039	COG0835	chemotaxis
ALT831_01039	COG0784	Response regulator, receiver
ALT831_01040	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ALT831_01041	COG1815	bacterial-type flagellum-dependent cell motility
ALT831_01044	COG1749	Flagellar hook protein flgE
ALT831_01045	COG4787	bacterial-type flagellum-dependent cell motility
ALT831_01049	COG3951	Flagellar rod assembly protein muramidase FlgJ
ALT831_01049	COG1705	Flagellar rod assembly protein muramidase FlgJ
ALT831_01050	COG1256	bacterial-type flagellum assembly
ALT831_01055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ALT831_01056	COG1334	flagellar protein FlaG
ALT831_01057	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ALT831_01065	COG0673	inositol 2-dehydrogenase activity
ALT831_01066	COG1083	cytidylyl-transferase
ALT831_01069	COG2089	acid synthase
ALT831_01070	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_01072	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALT831_01075	COG1086	Polysaccharide biosynthesis protein
ALT831_01078	COG3475	LICD family
ALT831_01079	COG2089	acid synthase
ALT831_01081	COG1083	cytidylyl-transferase
ALT831_01082	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ALT831_01087	COG1677	Flagellar hook-basal body complex protein FliE
ALT831_01088	COG1766	The M ring may be actively involved in energy transduction
ALT831_01089	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ALT831_01099	COG1987	bacterial-type flagellum assembly
ALT831_01103	COG2989	Protein conserved in bacteria
ALT831_01104	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ALT831_01109	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ALT831_01110	COG0643	Histidine kinase
ALT831_01110	COG0784	Response regulator, receiver
ALT831_01110	COG2198	Histidine kinase
ALT831_01111	COG2201	protein-glutamate methylesterase activity
ALT831_01112	COG1192	Involved in chromosome partitioning
ALT831_01114	COG0835	chemotaxis
ALT831_01117	COG1410	methionine synthase
ALT831_01117	COG0646	methionine synthase
ALT831_01118	COG1410	methionine synthase
ALT831_01118	COG0646	methionine synthase
ALT831_01120	COG3123	guanosine phosphorylase activity
ALT831_01122	COG0583	DNA-binding transcription factor activity
ALT831_01123	COG0583	DNA-binding transcription factor activity
ALT831_01124	COG0288	reversible hydration of carbon dioxide
ALT831_01125	COG0659	secondary active sulfate transmembrane transporter activity
ALT831_01127	COG1309	transcriptional regulator
ALT831_01128	COG3590	peptidase
ALT831_01130	COG2137	regulation of response to DNA damage stimulus
ALT831_01131	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ALT831_01136	COG1607	acyl-coa hydrolase
ALT831_01138	COG0511	ligase activity, forming carbon-carbon bonds
ALT831_01138	COG5016	pyruvate
ALT831_01139	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ALT831_01140	COG4172	Belongs to the ABC transporter superfamily
ALT831_01142	COG4171	peptide transport system, permease
ALT831_01143	COG4168	peptide transport system, permease
ALT831_01144	COG0747	negative chemotaxis
ALT831_01145	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ALT831_01146	COG1842	Phage shock protein A
ALT831_01152	COG0625	glutathione transferase activity
ALT831_01153	COG1522	sequence-specific DNA binding
ALT831_01165	COG0811	peptide transport
ALT831_01166	COG0811	peptide transport
ALT831_01167	COG0848	biopolymer transport protein
ALT831_01170	COG1444	tRNA N-acetyltransferase activity
ALT831_01179	COG0456	acetyltransferase
ALT831_01181	COG0583	DNA-binding transcription factor activity
ALT831_01182	COG2814	Major facilitator Superfamily
ALT831_01183	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALT831_01184	COG0656	L-ascorbic acid biosynthetic process
ALT831_01188	COG1846	Transcriptional regulator
ALT831_01190	COG3275	phosphorelay sensor kinase activity
ALT831_01191	COG1966	Carbon starvation protein
ALT831_01195	COG0457	Tetratricopeptide repeat
ALT831_01198	COG2197	response regulator
ALT831_01200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ALT831_01207	COG0583	DNA-binding transcription factor activity
ALT831_01208	COG0702	epimerase
ALT831_01212	COG1902	pentaerythritol trinitrate reductase activity
ALT831_01215	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ALT831_01216	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ALT831_01217	COG0564	pseudouridine synthase activity
ALT831_01219	COG0612	Peptidase, M16
ALT831_01220	COG2918	glutathione biosynthetic process
ALT831_01225	COG2840	Smr protein MutS2
ALT831_01226	COG2890	protein-(glutamine-N5) methyltransferase activity
ALT831_01229	COG2719	SpoVR family
ALT831_01230	COG2718	Belongs to the UPF0229 family
ALT831_01231	COG2766	serine protein kinase
ALT831_01232	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ALT831_01233	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ALT831_01234	COG4771	TonB-dependent receptor
ALT831_01239	COG0450	alkyl hydroperoxide reductase
ALT831_01240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ALT831_01241	COG2885	chlorophyll binding
ALT831_01242	COG0584	glycerophosphoryl diester phosphodiesterase
ALT831_01243	COG0346	lactoylglutathione lyase activity
ALT831_01244	COG4221	oxidoreductase activity
ALT831_01246	COG1278	Cold shock
ALT831_01249	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ALT831_01250	COG4660	Part of a membrane complex involved in electron transport
ALT831_01251	COG4659	FMN binding
ALT831_01252	COG4658	electron transport chain
ALT831_01253	COG4656	Part of a membrane complex involved in electron transport
ALT831_01254	COG2878	Part of a membrane complex involved in electron transport
ALT831_01255	COG4657	Part of a membrane complex involved in electron transport
ALT831_01258	COG0534	Mate efflux family protein
ALT831_01259	COG0556	nucleotide-excision repair
ALT831_01262	COG0602	queuosine metabolic process
ALT831_01264	COG0367	asparagine synthase
ALT831_01268	COG0471	metal ion transport
ALT831_01268	COG3273	potassium ion transport
ALT831_01271	COG0529	Catalyzes the synthesis of activated sulfate
ALT831_01272	COG0175	sulfate reduction
ALT831_01273	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALT831_01279	COG2304	oxidoreductase activity
ALT831_01283	COG0714	Associated with various cellular activities
ALT831_01285	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALT831_01285	COG1024	Enoyl-CoA hydratase
ALT831_01289	COG1025	Belongs to the peptidase M16 family
ALT831_01290	COG2062	phosphohistidine phosphatase, SixA
ALT831_01292	COG4536	flavin adenine dinucleotide binding
ALT831_01293	COG4137	Cytochrome C assembly protein
ALT831_01294	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ALT831_01302	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALT831_01303	COG1132	(ABC) transporter
ALT831_01306	COG0228	four-way junction DNA binding
ALT831_01307	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ALT831_01308	COG0336	Belongs to the RNA methyltransferase TrmD family
ALT831_01309	COG0335	large ribosomal subunit rRNA binding
ALT831_01310	COG2860	membrane
ALT831_01312	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ALT831_01313	COG0287	Prephenate dehydrogenase
ALT831_01313	COG1605	Chorismate mutase
ALT831_01319	COG0077	Prephenate dehydratase
ALT831_01319	COG1605	Chorismate mutase
ALT831_01320	COG0745	RESPONSE REGULATOR receiver
ALT831_01321	COG0023	Translation Initiation Factor
ALT831_01327	COG2205	protein histidine kinase activity
ALT831_01329	COG2204	response regulator
ALT831_01332	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ALT831_01333	COG0494	nUDIX hydrolase
ALT831_01334	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ALT831_01335	COG0632	four-way junction helicase activity
ALT831_01336	COG2255	four-way junction helicase activity
ALT831_01337	COG0824	Thioesterase
ALT831_01338	COG0811	peptide transport
ALT831_01341	COG0823	Involved in the tonB-independent uptake of proteins
ALT831_01342	COG2885	chlorophyll binding
ALT831_01343	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ALT831_01347	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ALT831_01355	COG0328	RNA-DNA hybrid ribonuclease activity
ALT831_01359	COG4667	esterase of the alpha-beta hydrolase superfamily
ALT831_01360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ALT831_01362	COG2205	protein histidine kinase activity
ALT831_01362	COG0784	Response regulator, receiver
ALT831_01365	COG3038	cytochrome b561
ALT831_01369	COG1451	nucleotide metabolic process
ALT831_01371	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALT831_01373	COG1309	transcriptional regulator
ALT831_01374	COG4774	siderophore transport
ALT831_01378	COG3706	GGDEF domain
ALT831_01380	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ALT831_01380	COG3008	intermembrane lipid transfer
ALT831_01381	COG2995	paraquat-inducible protein a
ALT831_01383	COG0017	Asparaginyl-tRNA synthetase
ALT831_01386	COG0189	ligase activity
ALT831_01393	COG2226	methyltransferase
ALT831_01396	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ALT831_01397	COG4139	cobalamin transport
ALT831_01398	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
ALT831_01399	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ALT831_01400	COG2205	protein histidine kinase activity
ALT831_01401	COG0745	RESPONSE REGULATOR receiver
ALT831_01402	COG0569	domain protein
ALT831_01403	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ALT831_01406	COG5265	(ABC) transporter
ALT831_01407	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ALT831_01409	COG0745	RESPONSE REGULATOR receiver
ALT831_01413	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALT831_01422	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ALT831_01425	COG2755	lipolytic protein G-D-S-L family
ALT831_01426	COG4181	ATPase activity
ALT831_01427	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ALT831_01428	COG1090	epimerase
ALT831_01429	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ALT831_01430	COG0628	permease
ALT831_01435	COG2350	Protein conserved in bacteria
ALT831_01436	COG0159	tryptophan synthase activity
ALT831_01438	COG0135	phosphoribosylanthranilate isomerase activity
ALT831_01438	COG0134	indole-3-glycerol-phosphate synthase activity
ALT831_01439	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ALT831_01441	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ALT831_01442	COG0613	PHP domain protein
ALT831_01443	COG0009	L-threonylcarbamoyladenylate synthase
ALT831_01445	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ALT831_01447	COG0656	L-ascorbic acid biosynthetic process
ALT831_01448	COG0110	maltose O-acetyltransferase activity
ALT831_01451	COG2733	membrane
ALT831_01452	COG0500	methyltransferase
ALT831_01453	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALT831_01454	COG0497	DNA recombination
ALT831_01455	COG0783	Belongs to the Dps family
ALT831_01456	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ALT831_01458	COG1454	alcohol dehydrogenase
ALT831_01459	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_01461	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ALT831_01462	COG2610	gluconate transmembrane transporter activity
ALT831_01463	COG4771	TonB-dependent receptor
ALT831_01466	COG0784	Response regulator, receiver
ALT831_01466	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALT831_01466	COG2198	Histidine kinase
ALT831_01466	COG2205	protein histidine kinase activity
ALT831_01468	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ALT831_01470	COG0484	heat shock protein binding
ALT831_01471	COG3909	cytochrome
ALT831_01474	COG2202	Pas domain
ALT831_01474	COG2199	diguanylate cyclase activity
ALT831_01474	COG2200	EAL domain
ALT831_01477	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ALT831_01479	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ALT831_01480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALT831_01485	COG0071	Belongs to the small heat shock protein (HSP20) family
ALT831_01487	COG0280	phosphate acetyltransferase
ALT831_01487	COG0857	belongs to the CobB CobQ family
ALT831_01488	COG1228	amidohydrolase
ALT831_01489	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ALT831_01490	COG4535	Mg2 and Co2 transporter CorC
ALT831_01492	COG1702	phosphate starvation-inducible protein PhoH
ALT831_01494	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALT831_01504	COG1607	acyl-coa hydrolase
ALT831_01505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ALT831_01507	COG1115	amino acid carrier protein
ALT831_01517	COG0012	GTP binding
ALT831_01520	COG1064	alcohol dehydrogenase
ALT831_01522	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ALT831_01524	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ALT831_01526	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ALT831_01528	COG2890	protein-(glutamine-N5) methyltransferase activity
ALT831_01529	COG0784	Response regulator, receiver
ALT831_01529	COG3437	response regulator, receiver
ALT831_01531	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ALT831_01533	COG0583	DNA-binding transcription factor activity
ALT831_01535	COG2363	Small membrane protein
ALT831_01540	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
ALT831_01541	COG0515	serine threonine protein kinase
ALT831_01542	COG2116	formate transmembrane transporter activity
ALT831_01545	COG0714	Associated with various cellular activities
ALT831_01546	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ALT831_01547	COG0033	Phosphoglucomutase
ALT831_01548	COG0058	SHG alpha-glucan phosphorylase activity
ALT831_01551	COG2988	succinylglutamate desuccinylase activity
ALT831_01554	COG1301	dicarboxylic acid transport
ALT831_01558	COG1393	Belongs to the ArsC family
ALT831_01564	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ALT831_01568	COG5001	Diguanylate cyclase
ALT831_01568	COG3300	MHYT domain
ALT831_01574	COG2249	NAD(P)H dehydrogenase (quinone) activity
ALT831_01579	COG1733	regulation of RNA biosynthetic process
ALT831_01581	COG5001	Diguanylate cyclase
ALT831_01581	COG5002	protein histidine kinase activity
ALT831_01581	COG3447	MASE1 domain protein
ALT831_01583	COG0402	S-adenosylhomocysteine deaminase activity
ALT831_01584	COG2351	hydroxyisourate hydrolase activity
ALT831_01587	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ALT831_01589	COG1309	transcriptional regulator
ALT831_01592	COG2252	PERMEase
ALT831_01593	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ALT831_01597	COG2205	protein histidine kinase activity
ALT831_01597	COG0784	Response regulator, receiver
ALT831_01600	COG2233	PERMEase
ALT831_01601	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ALT831_01604	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ALT831_01605	COG0730	response to heat
ALT831_01607	COG0154	amidase activity
ALT831_01613	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_01614	COG3001	Fructosamine kinase
ALT831_01616	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ALT831_01620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ALT831_01622	COG1596	polysaccharide export
ALT831_01623	COG0489	protein tyrosine kinase activity
ALT831_01624	COG4464	protein tyrosine phosphatase activity
ALT831_01631	COG0438	transferase activity, transferring glycosyl groups
ALT831_01633	COG1045	serine acetyltransferase
ALT831_01636	COG1215	transferase activity, transferring glycosyl groups
ALT831_01637	COG1216	Glycosyl transferase, family 2
ALT831_01638	COG2244	polysaccharide biosynthetic process
ALT831_01646	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALT831_01646	COG0072	phenylalanine-tRNA ligase activity
ALT831_01651	COG1472	Belongs to the glycosyl hydrolase 3 family
ALT831_01652	COG2096	Adenosyltransferase
ALT831_01654	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ALT831_01656	COG4591	ABC-type transport system involved in lipoprotein release permease component
ALT831_01661	COG0708	Exodeoxyribonuclease III
ALT831_01668	COG2814	Major facilitator Superfamily
ALT831_01675	COG4770	biotin carboxylase activity
ALT831_01676	COG1024	Enoyl-CoA hydratase
ALT831_01677	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALT831_01678	COG1960	acyl-CoA dehydrogenase activity
ALT831_01679	COG0789	Transcriptional regulator
ALT831_01680	COG0183	Belongs to the thiolase family
ALT831_01685	COG2925	Exonuclease
ALT831_01686	COG0784	Response regulator, receiver
ALT831_01686	COG2205	protein histidine kinase activity
ALT831_01686	COG5002	protein histidine kinase activity
ALT831_01694	COG1643	Atp-dependent helicase
ALT831_01698	COG3321	synthase
ALT831_01698	COG0604	alcohol dehydrogenase
ALT831_01699	COG0328	RNA-DNA hybrid ribonuclease activity
ALT831_01700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ALT831_01706	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ALT831_01707	COG1136	(ABC) transporter
ALT831_01708	COG4591	ABC-type transport system involved in lipoprotein release permease component
ALT831_01709	COG1301	dicarboxylic acid transport
ALT831_01711	COG3724	N-succinylarginine dihydrolase activity
ALT831_01712	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ALT831_01713	COG3122	Protein conserved in bacteria
ALT831_01715	COG0583	DNA-binding transcription factor activity
ALT831_01716	COG0746	molybdenum cofactor guanylyltransferase activity
ALT831_01717	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ALT831_01718	COG0243	molybdopterin cofactor binding
ALT831_01720	COG0625	glutathione transferase activity
ALT831_01723	COG2153	protein acetylation
ALT831_01726	COG5002	protein histidine kinase activity
ALT831_01728	COG1530	ribonuclease E activity
ALT831_01729	COG0564	pseudouridine synthase activity
ALT831_01730	COG0546	phosphoglycolate phosphatase activity
ALT831_01731	COG0424	maF-like protein
ALT831_01732	COG1399	metal-binding, possibly nucleic acid-binding protein
ALT831_01734	COG0416	fatty acid biosynthetic process
ALT831_01735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ALT831_01736	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ALT831_01738	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ALT831_01739	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ALT831_01740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ALT831_01741	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ALT831_01744	COG0084	hydrolase, TatD family'
ALT831_01745	COG0259	pyridoxamine-phosphate oxidase activity
ALT831_01746	COG0702	epimerase
ALT831_01747	COG3706	GGDEF domain
ALT831_01752	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_01753	COG0596	Alpha beta hydrolase
ALT831_01754	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALT831_01754	COG1024	Enoyl-CoA hydratase
ALT831_01755	COG0183	Belongs to the thiolase family
ALT831_01756	COG1960	acyl-CoA dehydrogenase activity
ALT831_01757	COG0596	Alpha beta hydrolase
ALT831_01760	COG2390	Transcriptional regulator
ALT831_01761	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ALT831_01763	COG0246	Mannitol dehydrogenase
ALT831_01766	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ALT831_01767	COG0523	cobalamin synthesis protein
ALT831_01768	COG0247	lactate metabolic process
ALT831_01768	COG0277	FAD linked oxidase domain protein
ALT831_01773	COG0668	transmembrane transport
ALT831_01774	COG4771	TonB-dependent receptor
ALT831_01779	COG0784	Response regulator, receiver
ALT831_01779	COG2198	Histidine kinase
ALT831_01779	COG2205	protein histidine kinase activity
ALT831_01780	COG3437	response regulator, receiver
ALT831_01782	COG0195	Participates in both transcription termination and antitermination
ALT831_01785	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ALT831_01789	COG5001	Diguanylate cyclase
ALT831_01789	COG3300	MHYT domain
ALT831_01790	COG1187	pseudouridine synthase activity
ALT831_01792	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ALT831_01792	COG3153	acetyltransferase
ALT831_01809	COG1032	radical SAM domain protein
ALT831_01812	COG4771	TonB-dependent receptor
ALT831_01813	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALT831_01815	COG4134	Bacterial extracellular solute-binding protein
ALT831_01817	COG4136	ATPase activity
ALT831_01818	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ALT831_01821	COG0604	alcohol dehydrogenase
ALT831_01826	COG0583	DNA-binding transcription factor activity
ALT831_01831	COG1131	(ABC) transporter
ALT831_01835	COG0582	viral genome integration into host DNA
ALT831_01839	COG3012	SEC-C Motif Domain Protein
ALT831_01843	COG1902	pentaerythritol trinitrate reductase activity
ALT831_01845	COG2867	negative regulation of translational initiation
ALT831_01846	COG2914	Belongs to the UPF0125 (RnfH) family
ALT831_01848	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ALT831_01849	COG4771	TonB-dependent receptor
ALT831_01850	COG0457	Tetratricopeptide repeat
ALT831_01854	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ALT831_01854	COG0574	Belongs to the PEP-utilizing enzyme family
ALT831_01862	COG2850	peptidyl-arginine hydroxylation
ALT831_01864	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ALT831_01865	COG2915	High frequency lysogenization protein hflD homolog
ALT831_01866	COG0482	sulfurtransferase activity
ALT831_01867	COG1187	pseudouridine synthase activity
ALT831_01870	COG1278	Cold shock
ALT831_01871	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ALT831_01872	COG0542	response to heat
ALT831_01873	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ALT831_01874	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ALT831_01875	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ALT831_01876	COG0492	ferredoxin-NADP+ reductase activity
ALT831_01877	COG3092	negative regulation of chromosome organization
ALT831_01878	COG0616	signal peptide processing
ALT831_01880	COG0778	Nitroreductase
ALT831_01882	COG0252	asparaginase activity
ALT831_01883	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ALT831_01884	COG0321	lipoyl(octanoyl) transferase activity
ALT831_01885	COG2921	Belongs to the UPF0250 family
ALT831_01886	COG1686	Belongs to the peptidase S11 family
ALT831_01887	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ALT831_01888	COG0772	Belongs to the SEDS family
ALT831_01889	COG0768	penicillin binding
ALT831_01890	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ALT831_01891	COG0799	negative regulation of ribosome biogenesis
ALT831_01892	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ALT831_01893	COG1466	dna polymerase III delta subunit
ALT831_01894	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ALT831_01895	COG0495	leucyl-tRNA aminoacylation
ALT831_01897	COG1067	ATP-dependent peptidase activity
ALT831_01901	COG1534	Rna-binding protein
ALT831_01902	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ALT831_01903	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ALT831_01904	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ALT831_01905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ALT831_01906	COG0149	triose-phosphate isomerase activity
ALT831_01907	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ALT831_01913	COG1597	lipid kinase activity
ALT831_01913	COG1803	Methylglyoxal synthase
ALT831_01915	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_01916	COG0561	phosphatase activity
ALT831_01919	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALT831_01920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ALT831_01921	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ALT831_01924	COG1185	polyribonucleotide nucleotidyltransferase activity
ALT831_01928	COG3547	Transposase (IS116 IS110 IS902 family)
ALT831_01932	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ALT831_01941	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ALT831_01957	COG2223	nitrite transmembrane transporter activity
ALT831_01966	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ALT831_01967	COG1196	nuclear chromosome segregation
ALT831_01969	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ALT831_01973	COG1132	(ABC) transporter
ALT831_01974	COG1663	tetraacyldisaccharide 4'-kinase activity
ALT831_01981	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ALT831_01982	COG0435	Glutathione S-transferase
ALT831_01983	COG1741	Belongs to the pirin family
ALT831_01988	COG0372	Belongs to the citrate synthase family
ALT831_01990	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ALT831_01991	COG1053	succinate dehydrogenase
ALT831_01992	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ALT831_01993	COG0567	Dehydrogenase, E1 component
ALT831_01994	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALT831_02001	COG4667	esterase of the alpha-beta hydrolase superfamily
ALT831_02005	COG0366	Alpha amylase catalytic
ALT831_02008	COG1609	Transcriptional regulator
ALT831_02010	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_02011	COG2267	carboxylic ester hydrolase activity
ALT831_02013	COG0616	signal peptide processing
ALT831_02016	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ALT831_02017	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ALT831_02018	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALT831_02019	COG0386	Belongs to the glutathione peroxidase family
ALT831_02020	COG2084	Dehydrogenase
ALT831_02022	COG1960	acyl-CoA dehydrogenase activity
ALT831_02023	COG1024	Enoyl-CoA hydratase
ALT831_02024	COG2226	methyltransferase
ALT831_02025	COG3083	sulfuric ester hydrolase activity
ALT831_02026	COG3082	Protein of unknown function (DUF1414)
ALT831_02027	COG3081	Nucleoid-associated protein
ALT831_02029	COG0739	heme binding
ALT831_02029	COG1196	nuclear chromosome segregation
ALT831_02029	COG0741	lytic transglycosylase activity
ALT831_02033	COG3275	phosphorelay sensor kinase activity
ALT831_02034	COG3279	Response regulator of the LytR AlgR family
ALT831_02035	COG0205	6-phosphofructokinase activity
ALT831_02038	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALT831_02038	COG2205	protein histidine kinase activity
ALT831_02040	COG1054	Belongs to the UPF0176 family
ALT831_02049	COG0513	Belongs to the DEAD box helicase family
ALT831_02051	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ALT831_02052	COG0583	DNA-binding transcription factor activity
ALT831_02056	COG1760	l-serine dehydratase
ALT831_02060	COG1322	Protein conserved in bacteria
ALT831_02061	COG1404	Belongs to the peptidase S8 family
ALT831_02062	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ALT831_02063	COG0022	dehydrogenase e1 component
ALT831_02065	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ALT831_02066	COG0515	serine threonine protein kinase
ALT831_02067	COG1946	Acyl-CoA thioesterase
ALT831_02070	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ALT831_02072	COG1956	GAF domain-containing protein
ALT831_02075	COG0793	Belongs to the peptidase S41A family
ALT831_02076	COG0733	neurotransmitter:sodium symporter activity
ALT831_02077	COG1757	Na H antiporter
ALT831_02078	COG0308	aminopeptidase N
ALT831_02085	COG0167	dihydroorotate dehydrogenase activity
ALT831_02088	COG0488	(ABC) transporter
ALT831_02090	COG3130	regulation of translation
ALT831_02091	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ALT831_02093	COG0415	Belongs to the DNA photolyase family
ALT831_02094	COG0415	Belongs to the DNA photolyase family
ALT831_02095	COG0415	Belongs to the DNA photolyase family
ALT831_02096	COG3046	protein related to deoxyribodipyrimidine photolyase
ALT831_02098	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALT831_02101	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ALT831_02102	COG0589	response to stress
ALT831_02104	COG0069	glutamate synthase activity
ALT831_02107	COG2193	ferroxidase activity
ALT831_02109	COG3278	Belongs to the heme-copper respiratory oxidase family
ALT831_02112	COG2010	Cytochrome c
ALT831_02117	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALT831_02118	COG0589	response to stress
ALT831_02119	COG0037	tRNA processing
ALT831_02120	COG1752	Esterase of the alpha-beta hydrolase superfamily
ALT831_02124	COG1280	lysine exporter protein (LysE YggA)
ALT831_02126	COG2897	thiosulfate sulfurtransferase activity
ALT831_02127	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ALT831_02128	COG3148	PFAM DTW domain containing protein
ALT831_02133	COG0322	excinuclease ABC activity
ALT831_02134	COG2197	response regulator
ALT831_02135	COG1741	Belongs to the pirin family
ALT831_02136	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALT831_02137	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ALT831_02141	COG3384	dioxygenase
ALT831_02142	COG2259	Doxx family
ALT831_02143	COG0583	DNA-binding transcription factor activity
ALT831_02146	COG0670	Belongs to the BI1 family
ALT831_02147	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ALT831_02150	COG2920	part of a sulfur-relay system
ALT831_02154	COG4206	TonB-dependent receptor
ALT831_02154	COG4206	TonB-dependent receptor
ALT831_02157	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ALT831_02158	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ALT831_02159	COG0531	amino acid
ALT831_02159	COG1674	ftsk spoiiie
ALT831_02162	COG0686	Belongs to the AlaDH PNT family
ALT831_02163	COG0284	orotidine-5'-phosphate decarboxylase activity
ALT831_02164	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ALT831_02168	COG0776	regulation of translation
ALT831_02169	COG0539	negative regulation of cytoplasmic translation
ALT831_02170	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ALT831_02171	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ALT831_02172	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ALT831_02174	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ALT831_02175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALT831_02176	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALT831_02177	COG0633	Ferredoxin
ALT831_02178	COG4221	oxidoreductase activity
ALT831_02186	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ALT831_02187	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALT831_02189	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALT831_02190	COG4974	Belongs to the 'phage' integrase family
ALT831_02194	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALT831_02205	COG4783	chaperone-mediated protein folding
ALT831_02206	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALT831_02207	COG1393	Belongs to the ArsC family
ALT831_02214	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ALT831_02216	COG1960	acyl-CoA dehydrogenase activity
ALT831_02221	COG0572	uridine kinase
ALT831_02222	COG3769	mannosylglycerate metabolic process
ALT831_02223	COG1215	transferase activity, transferring glycosyl groups
ALT831_02226	COG0303	'Molybdopterin
ALT831_02227	COG0534	Mate efflux family protein
ALT831_02231	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ALT831_02244	COG3011	Protein conserved in bacteria
ALT831_02253	COG0405	Gamma-glutamyltransferase
ALT831_02254	COG1024	Enoyl-CoA hydratase
ALT831_02266	COG1671	Belongs to the UPF0178 family
ALT831_02267	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_02268	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_02269	COG1960	acyl-CoA dehydrogenase activity
ALT831_02270	COG0662	Cupin 2, conserved barrel domain protein
ALT831_02270	COG2207	Transcriptional regulator
ALT831_02273	COG1505	serine-type exopeptidase activity
ALT831_02281	COG0596	Alpha beta hydrolase
ALT831_02283	COG0716	FMN binding
ALT831_02285	COG0735	belongs to the Fur family
ALT831_02287	COG1984	allophanate hydrolase subunit 2
ALT831_02288	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ALT831_02289	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ALT831_02290	COG2996	Protein conserved in bacteria
ALT831_02291	COG1765	OsmC-like protein
ALT831_02292	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALT831_02294	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALT831_02297	COG0436	Aminotransferase
ALT831_02298	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ALT831_02299	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ALT831_02305	COG3012	SEC-C Motif Domain Protein
ALT831_02306	COG0366	Alpha amylase catalytic
ALT831_02307	COG0604	alcohol dehydrogenase
ALT831_02309	COG1960	acyl-CoA dehydrogenase activity
ALT831_02311	COG4771	TonB-dependent receptor
ALT831_02316	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ALT831_02320	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ALT831_02321	COG0315	cyclic pyranopterin monophosphate synthase activity
ALT831_02322	COG0521	Mo-molybdopterin cofactor biosynthetic process
ALT831_02323	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ALT831_02325	COG2423	ornithine cyclodeaminase activity
ALT831_02326	COG0436	Aminotransferase
ALT831_02327	COG1522	sequence-specific DNA binding
ALT831_02330	COG0826	peptidase U32
ALT831_02331	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ALT831_02332	COG0436	Aminotransferase
ALT831_02333	COG3268	Saccharopine dehydrogenase
ALT831_02334	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALT831_02338	COG4771	TonB-dependent receptor
ALT831_02347	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALT831_02349	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ALT831_02350	COG1074	ATP-dependent DNA helicase activity
ALT831_02351	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ALT831_02354	COG1022	Amp-dependent synthetase and ligase
ALT831_02359	COG0583	DNA-binding transcription factor activity
ALT831_02363	COG0640	Transcriptional regulator
ALT831_02367	COG2204	response regulator
ALT831_02369	COG4251	negative regulation of phosphorylation
ALT831_02370	COG0784	Response regulator, receiver
ALT831_02371	COG0784	Response regulator, receiver
ALT831_02371	COG2205	protein histidine kinase activity
ALT831_02382	COG3139	Protein of unknown function (DUF1315)
ALT831_02384	COG1115	amino acid carrier protein
ALT831_02385	COG2866	Carboxypeptidase
ALT831_02389	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ALT831_02391	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ALT831_02392	COG1640	4-alpha-glucanotransferase
ALT831_02394	COG0676	glucose-6-phosphate 1-epimerase activity
ALT831_02395	COG0800	Aldolase
ALT831_02397	COG0129	dihydroxy-acid dehydratase activity
ALT831_02399	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ALT831_02400	COG1737	Transcriptional regulator
ALT831_02401	COG0469	pyruvate kinase activity
ALT831_02406	COG2823	Periplasmic or secreted lipoprotein
ALT831_02412	COG3665	Urea carboxylase-associated protein
ALT831_02416	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_02417	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ALT831_02419	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ALT831_02422	COG2721	sulfolactate sulfo-lyase activity
ALT831_02423	COG1904	glucuronate isomerase
ALT831_02424	COG0246	Mannitol dehydrogenase
ALT831_02425	COG0800	Aldolase
ALT831_02426	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALT831_02427	COG2755	lipolytic protein G-D-S-L family
ALT831_02430	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ALT831_02432	COG4677	pectinesterase activity
ALT831_02436	COG2356	endonuclease I
ALT831_02441	COG0583	DNA-binding transcription factor activity
ALT831_02443	COG1979	alcohol dehydrogenase
ALT831_02444	COG1902	pentaerythritol trinitrate reductase activity
ALT831_02445	COG2203	Gaf domain
ALT831_02445	COG3706	GGDEF domain
ALT831_02445	COG5001	Diguanylate cyclase
ALT831_02445	COG4251	negative regulation of phosphorylation
ALT831_02447	COG0753	catalase activity
ALT831_02448	COG0784	Response regulator, receiver
ALT831_02448	COG3437	response regulator, receiver
ALT831_02449	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALT831_02449	COG4191	Histidine kinase
ALT831_02460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ALT831_02466	COG0471	metal ion transport
ALT831_02468	COG0489	protein tyrosine kinase activity
ALT831_02469	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALT831_02469	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALT831_02470	COG0668	transmembrane transport
ALT831_02472	COG2226	methyltransferase
ALT831_02473	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALT831_02474	COG0741	lytic transglycosylase activity
ALT831_02474	COG1388	LysM domain
ALT831_02478	COG3138	arginine N-succinyltransferase
ALT831_02479	COG0215	cysteine-tRNA ligase activity
ALT831_02480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ALT831_02481	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALT831_02483	COG2268	Band 7 protein
ALT831_02484	COG0583	DNA-binding transcription factor activity
ALT831_02485	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_02488	COG1733	regulation of RNA biosynthetic process
ALT831_02489	COG0604	alcohol dehydrogenase
ALT831_02490	COG0861	Integral membrane protein TerC family
ALT831_02491	COG1063	alcohol dehydrogenase
ALT831_02492	COG0583	DNA-binding transcription factor activity
ALT831_02499	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ALT831_02500	COG1286	toxin biosynthetic process
ALT831_02501	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ALT831_02502	COG0285	dihydrofolate synthase activity
ALT831_02507	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ALT831_02510	COG0596	Alpha beta hydrolase
ALT831_02512	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ALT831_02513	COG0318	PFAM AMP-dependent synthetase and ligase
ALT831_02515	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ALT831_02515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALT831_02523	COG0789	Transcriptional regulator
ALT831_02525	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_02526	COG1119	ATPase activity
ALT831_02528	COG0523	cobalamin synthesis protein
ALT831_02529	COG1917	Cupin 2, conserved barrel domain protein
ALT831_02529	COG4977	sequence-specific DNA binding
ALT831_02530	COG1335	isochorismatase
ALT831_02532	COG2031	fatty acid transporter
ALT831_02533	COG0784	Response regulator, receiver
ALT831_02533	COG5002	protein histidine kinase activity
ALT831_02533	COG2205	protein histidine kinase activity
ALT831_02534	COG0612	Peptidase, M16
ALT831_02537	COG3101	peptidyl-lysine hydroxylation
ALT831_02542	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALT831_02542	COG1902	pentaerythritol trinitrate reductase activity
ALT831_02547	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ALT831_02549	COG4399	Belongs to the UPF0754 family
ALT831_02556	COG2186	Transcriptional regulator
ALT831_02558	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ALT831_02559	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ALT831_02560	COG2983	Belongs to the UPF0260 family
ALT831_02561	COG0179	Fumarylacetoacetate (FAA) hydrolase
ALT831_02564	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ALT831_02565	COG0318	PFAM AMP-dependent synthetase and ligase
ALT831_02566	COG2267	carboxylic ester hydrolase activity
ALT831_02569	COG1214	PFAM Peptidase M22, glycoprotease
ALT831_02570	COG1199	ATP-dependent helicase activity
ALT831_02588	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ALT831_02589	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ALT831_02590	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALT831_02591	COG0131	Imidazoleglycerol-phosphate dehydratase
ALT831_02591	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ALT831_02592	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ALT831_02598	COG2116	formate transmembrane transporter activity
ALT831_02599	COG0612	Peptidase, M16
ALT831_02605	COG0326	Molecular chaperone. Has ATPase activity
ALT831_02606	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ALT831_02621	COG0582	viral genome integration into host DNA
ALT831_02624	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ALT831_02625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ALT831_02628	COG3220	belongs to the UPF0276 family
ALT831_02636	COG1183	phosphatidylcholine synthase activity
ALT831_02640	COG0277	FAD linked oxidase domain protein
ALT831_02641	COG1620	l-lactate permease
ALT831_02645	COG0542	response to heat
ALT831_02650	COG1595	DNA-templated transcription, initiation
ALT831_02653	COG4221	oxidoreductase activity
ALT831_02656	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ALT831_02658	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ALT831_02660	COG0142	geranyltranstransferase activity
ALT831_02664	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ALT831_02665	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ALT831_02667	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ALT831_02670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALT831_02670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALT831_02673	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALT831_02674	COG0488	(ABC) transporter
ALT831_02676	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ALT831_02678	COG0560	Phosphoserine phosphatase
ALT831_02680	COG0084	hydrolase, TatD family'
ALT831_02683	COG0571	ribonuclease III activity
ALT831_02689	COG1595	DNA-templated transcription, initiation
ALT831_02690	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ALT831_02693	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ALT831_02697	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ALT831_02709	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ALT831_02710	COG1047	Peptidyl-prolyl cis-trans
ALT831_02712	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ALT831_02713	COG0196	riboflavin kinase activity
ALT831_02714	COG0728	peptidoglycan biosynthetic process
ALT831_02715	COG0268	Binds directly to 16S ribosomal RNA
ALT831_02718	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_02719	COG0385	Bile acid
ALT831_02725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALT831_02726	COG0776	regulation of translation
ALT831_02727	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ALT831_02728	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ALT831_02729	COG0740	serine-type endopeptidase activity
ALT831_02730	COG0544	peptidyl-prolyl cis-trans isomerase activity
ALT831_02741	COG1720	tRNA m6t6A37 methyltransferase activity
ALT831_02743	COG1234	tRNA 3'-trailer cleavage
ALT831_02745	COG0123	including yeast histone deacetylase and acetoin utilization protein
ALT831_02748	COG0516	GMP reductase activity
ALT831_02748	COG0517	IMP dehydrogenase activity
ALT831_02749	COG1570	exodeoxyribonuclease VII activity
ALT831_02754	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALT831_02755	COG2976	Protein conserved in bacteria
ALT831_02759	COG3063	Type IV pilus biogenesis stability protein PilW
ALT831_02760	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ALT831_02762	COG2166	iron-sulfur cluster assembly
ALT831_02765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ALT831_02766	COG0719	Fe-S assembly protein
ALT831_02767	COG0396	ATPase activity
ALT831_02768	COG0719	Fe-S assembly protein
ALT831_02769	COG1104	cysteine desulfurase activity
ALT831_02770	COG1959	2 iron, 2 sulfur cluster binding
ALT831_02772	COG2072	flavoprotein involved in K transport
ALT831_02773	COG1045	serine acetyltransferase
ALT831_02774	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ALT831_02775	COG0483	inositol monophosphate 1-phosphatase activity
ALT831_02777	COG3279	Response regulator of the LytR AlgR family
ALT831_02778	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ALT831_02779	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ALT831_02780	COG1862	Preprotein translocase
ALT831_02781	COG0343	queuine tRNA-ribosyltransferase activity
ALT831_02785	COG1842	Phage shock protein A
ALT831_02786	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ALT831_02790	COG0754	glutathionylspermidine amidase activity
ALT831_02796	COG2066	Belongs to the glutaminase family
ALT831_02797	COG1785	Belongs to the alkaline phosphatase family
ALT831_02798	COG0745	RESPONSE REGULATOR receiver
ALT831_02817	COG0438	transferase activity, transferring glycosyl groups
ALT831_02820	COG0367	asparagine synthase
ALT831_02821	COG0438	transferase activity, transferring glycosyl groups
ALT831_02827	COG2963	transposase activity
ALT831_02829	COG2244	polysaccharide biosynthetic process
ALT831_02839	COG0489	protein tyrosine kinase activity
ALT831_02841	COG3267	Type II secretory pathway component ExeA
ALT831_02841	COG3409	Peptidoglycan-binding domain 1 protein
ALT831_02842	COG2827	Endonuclease containing a URI domain
ALT831_02846	COG1560	Kdo2-lipid A biosynthetic process
ALT831_02850	COG1960	acyl-CoA dehydrogenase activity
ALT831_02854	COG1435	thymidine kinase activity
ALT831_02857	COG1609	Transcriptional regulator
ALT831_02858	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ALT831_02862	COG1082	Xylose isomerase domain protein TIM barrel
ALT831_02863	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ALT831_02864	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALT831_02867	COG1982	Orn Lys Arg decarboxylase major
ALT831_02873	COG1012	belongs to the aldehyde dehydrogenase family
ALT831_02877	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ALT831_02878	COG0789	Transcriptional regulator
ALT831_02884	COG1960	acyl-CoA dehydrogenase activity
ALT831_02896	COG2080	2 iron, 2 sulfur cluster binding
ALT831_02897	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ALT831_02898	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ALT831_02907	COG0601	transmembrane transport
ALT831_02908	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ALT831_02909	COG4172	Belongs to the ABC transporter superfamily
ALT831_02910	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_02912	COG0693	protein deglycase activity
ALT831_02913	COG1295	ribonuclease BN
ALT831_02915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ALT831_02917	COG3279	Response regulator of the LytR AlgR family
ALT831_02925	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ALT831_02934	COG2814	Major facilitator Superfamily
ALT831_02935	COG0339	signal peptide processing
ALT831_02943	COG0514	ATP-dependent DNA helicase (RecQ)
ALT831_02948	COG4251	negative regulation of phosphorylation
ALT831_02949	COG2133	pyrroloquinoline quinone binding
ALT831_02957	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ALT831_02957	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ALT831_02960	COG0738	Major facilitator superfamily
ALT831_02961	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ALT831_02963	COG2971	BadF BadG BcrA BcrD
ALT831_02968	COG0583	DNA-binding transcription factor activity
ALT831_02973	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALT831_02974	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALT831_02975	COG0006	proline dipeptidase activity
ALT831_02978	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALT831_02980	COG2205	protein histidine kinase activity
ALT831_02981	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ALT831_02982	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ALT831_02983	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ALT831_02991	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALT831_02992	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALT831_02993	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ALT831_02997	COG3577	Aspartyl protease
ALT831_02998	COG0157	Belongs to the NadC ModD family
ALT831_02999	COG4969	Belongs to the N-Me-Phe pilin family
ALT831_03000	COG1459	type II secretion system
ALT831_03001	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ALT831_03002	COG0237	dephospho-CoA kinase activity
ALT831_03002	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ALT831_03003	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ALT831_03004	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ALT831_03005	COG3608	succinylglutamate desuccinylase aspartoacylase
ALT831_03006	COG0840	transmembrane signaling receptor activity
ALT831_03007	COG4566	intracellular signal transduction
ALT831_03010	COG0643	Histidine kinase
ALT831_03010	COG2198	Histidine kinase
ALT831_03012	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ALT831_03014	COG2201	protein-glutamate methylesterase activity
ALT831_03015	COG0835	chemotaxis
ALT831_03016	COG0840	transmembrane signaling receptor activity
ALT831_03017	COG0494	nUDIX hydrolase
ALT831_03019	COG0739	heme binding
ALT831_03020	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ALT831_03021	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ALT831_03022	COG0849	cell division
ALT831_03023	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ALT831_03024	COG1181	Belongs to the D-alanine--D-alanine ligase family
ALT831_03027	COG0772	Belongs to the SEDS family
ALT831_03028	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ALT831_03030	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ALT831_03031	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ALT831_03032	COG0768	penicillin binding
ALT831_03033	COG3116	cell division
ALT831_03035	COG2001	Belongs to the MraZ family
ALT831_03039	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALT831_03040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALT831_03044	COG0678	peroxiredoxin activity
ALT831_03044	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ALT831_03049	COG2204	response regulator
ALT831_03054	COG0668	transmembrane transport
ALT831_03055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ALT831_03056	COG0189	ligase activity
ALT831_03057	COG1678	Uncharacterized ACR, COG1678
ALT831_03058	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ALT831_03063	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ALT831_03064	COG0762	integral membrane protein
ALT831_03066	COG1902	pentaerythritol trinitrate reductase activity
ALT831_03066	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALT831_03073	COG1764	response to oxidative stress
ALT831_03074	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALT831_03076	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ALT831_03077	COG1396	sequence-specific DNA binding
ALT831_03078	COG2814	Major facilitator Superfamily
ALT831_03079	COG0724	RNA recognition motif
ALT831_03084	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ALT831_03085	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ALT831_03086	COG0083	homoserine kinase activity
ALT831_03089	COG0583	DNA-binding transcription factor activity
ALT831_03092	COG2197	response regulator
ALT831_03093	COG4585	Histidine kinase
ALT831_03096	COG0640	Transcriptional regulator
ALT831_03098	COG0431	NADPH-dependent FMN reductase
ALT831_03099	COG0798	PFAM Bile acid sodium symporter
ALT831_03100	COG2201	protein-glutamate methylesterase activity
ALT831_03101	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ALT831_03103	COG0642	Histidine kinase
ALT831_03107	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ALT831_03109	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ALT831_03114	COG1748	Saccharopine dehydrogenase
ALT831_03118	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ALT831_03119	COG3107	peptidoglycan biosynthetic process
ALT831_03120	COG0792	nuclease activity
ALT831_03123	COG2823	Periplasmic or secreted lipoprotein
ALT831_03127	COG4585	Histidine kinase
ALT831_03128	COG2197	response regulator
ALT831_03131	COG4771	TonB-dependent receptor
ALT831_03134	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ALT831_03135	COG0372	Belongs to the citrate synthase family
ALT831_03136	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ALT831_03137	COG2828	Protein conserved in bacteria
ALT831_03138	COG2199	diguanylate cyclase activity
ALT831_03138	COG2203	Gaf domain
ALT831_03142	COG2198	Histidine kinase
ALT831_03142	COG5002	protein histidine kinase activity
ALT831_03142	COG0784	Response regulator, receiver
ALT831_03144	COG0067	glutamate synthase
ALT831_03144	COG0069	glutamate synthase activity
ALT831_03144	COG0070	glutamate synthase
ALT831_03145	COG0493	'glutamate synthase
ALT831_03149	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ALT831_03150	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ALT831_03151	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ALT831_03152	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ALT831_03155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALT831_03156	COG5507	3-demethylubiquinone-9 3-methyltransferase
ALT831_03160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ALT831_03161	COG0741	lytic transglycosylase activity
ALT831_03161	COG1196	nuclear chromosome segregation
ALT831_03161	COG0739	heme binding
ALT831_03162	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ALT831_03164	COG0738	Major facilitator superfamily
ALT831_03166	COG1902	pentaerythritol trinitrate reductase activity
ALT831_03169	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ALT831_03170	COG0625	glutathione transferase activity
ALT831_03174	COG2894	cell division
ALT831_03175	COG0850	regulation of cytokinetic process
ALT831_03182	COG1981	membrane
ALT831_03185	COG1914	H( )-stimulated, divalent metal cation uptake system
ALT831_03186	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ALT831_03187	COG0745	RESPONSE REGULATOR receiver
ALT831_03188	COG1217	gtp-binding protein TYPA
ALT831_03190	COG0174	glutamine synthetase
ALT831_03192	COG3852	Histidine kinase
ALT831_03193	COG2204	response regulator
ALT831_03194	COG3437	response regulator, receiver
ALT831_03203	COG0525	valine-tRNA ligase activity
ALT831_03204	COG2927	DNA polymerase III (CHI subunit)
ALT831_03205	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ALT831_03206	COG0795	lipopolysaccharide-transporting ATPase activity
ALT831_03207	COG0795	lipopolysaccharide-transporting ATPase activity
ALT831_03223	COG1733	regulation of RNA biosynthetic process
ALT831_03226	COG0625	glutathione transferase activity
ALT831_03228	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ALT831_03229	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALT831_03230	COG1017	nitric oxide dioxygenase activity
ALT831_03230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ALT831_03231	COG3604	Transcriptional regulator
ALT831_03235	COG0673	inositol 2-dehydrogenase activity
ALT831_03237	COG0628	permease
ALT831_03243	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALT831_03245	COG0642	Histidine kinase
ALT831_03254	COG1971	Probably functions as a manganese efflux pump
ALT831_03259	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ALT831_03260	COG3706	GGDEF domain
ALT831_03261	COG0679	Auxin Efflux Carrier
ALT831_03262	COG2267	carboxylic ester hydrolase activity
ALT831_03268	COG1131	(ABC) transporter
ALT831_03270	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ALT831_03280	COG2205	protein histidine kinase activity
ALT831_03282	COG0348	domain, Protein
ALT831_03282	COG3901	Regulator of nitric oxide reductase transcription
ALT831_03284	COG2197	response regulator
ALT831_03292	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ALT831_03293	COG0583	DNA-binding transcription factor activity
ALT831_03294	COG1304	FMN binding
ALT831_03295	COG0277	FAD linked oxidase domain protein
ALT831_03297	COG1462	curli production assembly transport component CsgG
ALT831_03303	COG2197	response regulator
ALT831_03306	COG0513	Belongs to the DEAD box helicase family
ALT831_03307	COG3264	Mechanosensitive ion channel
ALT831_03307	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ALT831_03311	COG2200	EAL domain
ALT831_03311	COG2199	diguanylate cyclase activity
ALT831_03311	COG2202	Pas domain
ALT831_03316	COG0730	response to heat
ALT831_03317	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALT831_03320	COG4191	Histidine kinase
ALT831_03322	COG0417	DNA replication proofreading
ALT831_03324	COG0318	PFAM AMP-dependent synthetase and ligase
ALT831_03335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALT831_03337	COG1573	uracil-dna glycosylase
ALT831_03338	COG3300	MHYT domain
ALT831_03338	COG5001	Diguanylate cyclase
ALT831_03342	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ALT831_03346	COG1983	PspC domain protein
ALT831_03347	COG1842	Phage shock protein A
ALT831_03349	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ALT831_03352	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ALT831_03354	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ALT831_03355	COG0204	Acyl-transferase
ALT831_03356	COG0204	Acyl-transferase
ALT831_03357	COG0668	transmembrane transport
ALT831_03360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALT831_03361	COG0733	neurotransmitter:sodium symporter activity
ALT831_03364	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALT831_03367	COG0716	FMN binding
ALT831_03369	COG0848	biopolymer transport protein
ALT831_03371	COG0457	Tetratricopeptide repeat
ALT831_03372	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ALT831_03377	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ALT831_03378	COG0702	epimerase
ALT831_03381	COG5002	protein histidine kinase activity
ALT831_03381	COG5001	Diguanylate cyclase
ALT831_03383	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ALT831_03385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALT831_03387	COG0583	DNA-binding transcription factor activity
ALT831_03388	COG0121	glutamine amidotransferase
ALT831_03391	COG4682	membrane
ALT831_03395	COG1953	Uracil, thiamine, allantoin
ALT831_03396	COG4771	TonB-dependent receptor
ALT831_03398	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ALT831_03399	COG0778	Nitroreductase
ALT831_03400	COG0596	Alpha beta hydrolase
ALT831_03401	COG0251	oxidation-reduction process
ALT831_03402	COG1335	isochorismatase
ALT831_03403	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALT831_03404	COG1309	transcriptional regulator
ALT831_03407	COG4628	conserved protein (DUF2132)
ALT831_03408	COG2610	gluconate transmembrane transporter activity
ALT831_03409	COG3265	gluconokinase activity
ALT831_03410	COG1609	Transcriptional regulator
ALT831_03411	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALT831_03413	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ALT831_03417	COG1477	protein flavinylation
ALT831_03418	COG2871	sodium ion transport
ALT831_03419	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ALT831_03420	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ALT831_03421	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ALT831_03422	COG1805	sodium ion transport
ALT831_03423	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ALT831_03424	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ALT831_03425	COG0545	Peptidyl-prolyl cis-trans isomerase
ALT831_03426	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ALT831_03427	COG0039	L-malate dehydrogenase activity
ALT831_03428	COG1438	arginine binding
ALT831_03433	COG0572	uridine kinase
ALT831_03434	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ALT831_03437	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ALT831_03442	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALT831_03446	COG0189	ligase activity
ALT831_03448	COG0189	ligase activity
ALT831_03448	COG4067	protein conserved in archaea
ALT831_03451	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALT831_03453	COG1283	sodium-dependent phosphate transmembrane transporter activity
ALT831_03454	COG0667	Aldo Keto reductase
ALT831_03465	COG0753	catalase activity
ALT831_03473	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ALT831_03475	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ALT831_03476	COG0840	transmembrane signaling receptor activity
ALT831_03485	COG0583	DNA-binding transcription factor activity
ALT831_03492	COG0438	transferase activity, transferring glycosyl groups
ALT831_03492	COG1216	Glycosyl transferase, family 2
ALT831_03496	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ALT831_03505	COG1028	Short-chain dehydrogenase reductase Sdr
ALT831_03507	COG1083	cytidylyl-transferase
ALT831_03515	COG0438	transferase activity, transferring glycosyl groups
ALT831_03515	COG0297	glycogen (starch) synthase activity
ALT831_03517	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ALT831_03518	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ALT831_03523	COG0202	RNA polymerase activity
ALT831_03529	COG0201	protein transport
ALT831_03533	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ALT831_03540	COG5002	protein histidine kinase activity
ALT831_03540	COG0784	Response regulator, receiver
ALT831_03543	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALT831_03544	COG0557	exoribonuclease II activity
ALT831_03548	COG4771	TonB-dependent receptor
ALT831_03551	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ALT831_03555	COG2234	aminopeptidase activity
ALT831_03557	COG4251	negative regulation of phosphorylation
ALT831_03559	COG1271	oxidase subunit
ALT831_03560	COG1294	oxidase, subunit
ALT831_03563	COG1522	sequence-specific DNA binding
ALT831_03566	COG1278	Cold shock
ALT831_03567	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ALT831_03569	COG2226	methyltransferase
ALT831_03571	COG0339	signal peptide processing
ALT831_03572	COG2201	protein-glutamate methylesterase activity
ALT831_03576	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALT831_03577	COG0243	molybdopterin cofactor binding
ALT831_03580	COG4946	Tricorn protease homolog
ALT831_03580	COG1506	peptidase
ALT831_03580	COG0823	Involved in the tonB-independent uptake of proteins
ALT831_03590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALT831_03592	COG2197	response regulator
ALT831_03598	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ALT831_03599	COG1278	Cold shock
ALT831_03601	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ALT831_03602	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ALT831_03605	COG0281	malic enzyme
ALT831_03607	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ALT831_03613	COG0456	acetyltransferase
ALT831_03615	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ALT831_03616	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ALT831_03617	COG2177	Part of the ABC transporter FtsEX involved in
ALT831_03618	COG2884	Cell division ATP-binding protein ftsE
ALT831_03619	COG0552	protein localization to endoplasmic reticulum
ALT831_03620	COG0742	ribosomal rna small subunit methyltransferase
ALT831_03622	COG2095	MarC family integral membrane protein
ALT831_03626	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ALT831_03627	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALT831_03628	COG0617	tRNA 3'-terminal CCA addition
ALT831_03629	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ALT831_03632	COG0076	glutamate decarboxylase activity
ALT831_03635	COG0842	Transport permease protein
ALT831_03636	COG1131	(ABC) transporter
ALT831_03637	COG0745	RESPONSE REGULATOR receiver
ALT831_03638	COG2205	protein histidine kinase activity
ALT831_03642	COG1253	flavin adenine dinucleotide binding
ALT831_03643	COG0701	Predicted permease
ALT831_03644	COG1966	Carbon starvation protein
ALT831_03654	COG0848	biopolymer transport protein
ALT831_03656	COG0811	peptide transport
ALT831_03660	COG3128	pkhd-type hydroxylase
ALT831_03665	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ALT831_03666	COG0049	tRNA binding
ALT831_03667	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ALT831_03668	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ALT831_03669	COG0085	RNA polymerase activity
ALT831_03670	COG0222	ribosome binding
ALT831_03671	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ALT831_03672	COG0081	regulation of translation
ALT831_03673	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ALT831_03676	COG0250	Participates in transcription elongation, termination and antitermination
ALT831_03677	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ALT831_03679	COG1132	(ABC) transporter
ALT831_03680	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ALT831_03681	COG3590	peptidase
ALT831_03684	COG0513	Belongs to the DEAD box helicase family
ALT831_03686	COG0418	dihydroorotase activity
ALT831_03687	COG3040	lipid binding
ALT831_03688	COG4989	oxidoreductase activity
ALT831_03689	COG0346	lactoylglutathione lyase activity
ALT831_03690	COG0668	transmembrane transport
ALT831_03694	COG0302	gtp cyclohydrolase
ALT831_03696	COG2957	Belongs to the agmatine deiminase family
ALT831_03699	COG1201	RNA secondary structure unwinding
ALT831_03700	COG2311	Membrane
ALT831_03703	COG1793	dna ligase
ALT831_03704	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ALT831_03705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALT831_03710	COG0625	glutathione transferase activity
ALT831_03711	COG0625	glutathione transferase activity
ALT831_03713	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ALT831_03716	COG1012	belongs to the aldehyde dehydrogenase family
ALT831_03717	COG0028	Belongs to the TPP enzyme family
ALT831_03719	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ALT831_03720	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ALT831_03721	COG0330	HflC and HflK could
ALT831_03722	COG0330	HflC and HflK could
ALT831_03723	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ALT831_03724	COG1923	regulation of RNA biosynthetic process
ALT831_03725	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ALT831_03728	COG0802	atpase or kinase
ALT831_03729	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ALT831_03729	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ALT831_03730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ALT831_03734	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ALT831_03735	COG0735	belongs to the Fur family
ALT831_03739	COG0305	Participates in initiation and elongation during chromosome replication
ALT831_03744	COG2258	MOSC domain
ALT831_03758	COG0840	transmembrane signaling receptor activity
ALT831_03759	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALT831_03759	COG4191	Histidine kinase
ALT831_03760	COG0840	transmembrane signaling receptor activity
ALT831_03763	COG2855	membrane
ALT831_03764	COG2175	clavaminate synthase activity
ALT831_03765	COG0656	L-ascorbic acid biosynthetic process
ALT831_03769	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALT831_03770	COG4771	TonB-dependent receptor
ALT831_03774	COG3706	GGDEF domain
ALT831_03775	COG1757	Na H antiporter
ALT831_03776	COG1472	Belongs to the glycosyl hydrolase 3 family
ALT831_03778	COG2723	6-phospho-beta-galactosidase activity
ALT831_03779	COG1609	Transcriptional regulator
ALT831_03780	COG0477	Major facilitator Superfamily
ALT831_03780	COG2814	Major facilitator Superfamily
ALT831_03781	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ALT831_03782	COG4988	ABC transporter
ALT831_03783	COG4890	Cyd operon protein YbgT
ALT831_03784	COG1294	oxidase, subunit
ALT831_03792	COG4319	ketosteroid isomerase
ALT831_03793	COG1335	isochorismatase
ALT831_03794	COG2863	cytochrome
ALT831_03796	COG1741	Belongs to the pirin family
ALT831_03800	COG4771	TonB-dependent receptor
ALT831_03803	COG1469	GTP cyclohydrolase I activity
ALT831_03814	COG3237	CsbD-like
ALT831_03817	COG1595	DNA-templated transcription, initiation
ALT831_03823	COG0596	Alpha beta hydrolase
ALT831_03823	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALT831_03828	COG3038	cytochrome b561
ALT831_03830	COG1252	NADH dehydrogenase
ALT831_03831	COG4206	TonB-dependent receptor
ALT831_03834	COG0583	DNA-binding transcription factor activity
ALT831_03835	COG2067	long-chain fatty acid transport protein
ALT831_03836	COG2130	NADP-dependent
ALT831_03837	COG2203	Gaf domain
ALT831_03837	COG3706	GGDEF domain
ALT831_03837	COG4251	negative regulation of phosphorylation
ALT831_03837	COG5001	Diguanylate cyclase
ALT831_03838	COG0784	Response regulator, receiver
ALT831_03838	COG2205	protein histidine kinase activity
ALT831_03840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALT831_03841	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ALT831_03842	COG1349	DNA-binding transcription factor activity
ALT831_03843	COG0673	inositol 2-dehydrogenase activity
ALT831_03846	COG0697	spore germination
ALT831_03847	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ALT831_03848	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ALT831_03849	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ALT831_03850	COG1166	arginine decarboxylase activity
ALT831_03852	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ALT831_03868	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALT831_03870	COG0109	protoheme IX farnesyltransferase activity
ALT831_03874	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ALT831_03883	COG1324	tolerance protein
ALT831_03884	COG4232	protein-disulfide reductase activity
ALT831_03885	COG0739	heme binding
ALT831_03886	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ALT831_03887	COG0511	ligase activity, forming carbon-carbon bonds
ALT831_03888	COG0439	Biotin carboxylase
ALT831_03896	COG0154	amidase activity
ALT831_03899	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ALT831_03900	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ALT831_03903	COG0151	Belongs to the GarS family
ALT831_03906	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALT831_03907	COG3954	Phosphoribulokinase
ALT831_03912	COG1501	Belongs to the glycosyl hydrolase 31 family
ALT831_03913	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ALT831_03914	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ALT831_03916	COG3031	protein transport across the cell outer membrane
ALT831_03918	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ALT831_03919	COG1459	type II secretion system
ALT831_03920	COG2165	general secretion pathway protein
ALT831_03921	COG2165	general secretion pathway protein
ALT831_03922	COG2165	general secretion pathway protein
ALT831_03923	COG4795	General secretion pathway protein
ALT831_03926	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ALT831_03930	COG1012	belongs to the aldehyde dehydrogenase family
ALT831_03932	COG1011	Hydrolase
ALT831_03933	COG0494	nUDIX hydrolase
ALT831_03934	COG1218	3'(2'),5'-bisphosphate nucleotidase
ALT831_03936	COG2943	transferase activity, transferring hexosyl groups
ALT831_03937	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ALT831_03939	COG3089	Belongs to the UPF0270 family
ALT831_03940	COG0429	hydrolase of the alpha beta-hydrolase fold
ALT831_03942	COG0488	(ABC) transporter
ALT831_03948	COG0545	Peptidyl-prolyl cis-trans isomerase
ALT831_03950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALT831_03951	COG2183	response to ionizing radiation
ALT831_03956	COG1609	Transcriptional regulator
ALT831_03956	COG2207	Transcriptional regulator
ALT831_03957	COG2211	Major facilitator Superfamily
ALT831_03962	COG3693	PFAM glycoside hydrolase, family 10
ALT831_03963	COG0667	Aldo Keto reductase
ALT831_03964	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ALT831_03965	COG2115	Belongs to the xylose isomerase family
ALT831_03966	COG1070	Carbohydrate kinase
ALT831_03969	COG1472	Belongs to the glycosyl hydrolase 3 family
ALT831_03970	COG0477	Major facilitator Superfamily
ALT831_03978	COG0596	Alpha beta hydrolase
ALT831_03979	COG1040	competence protein
ALT831_03982	COG1794	racemase activity, acting on amino acids and derivatives
ALT831_03985	COG0534	Mate efflux family protein
ALT831_03988	COG1999	signal sequence binding
ALT831_03989	COG0109	protoheme IX farnesyltransferase activity
ALT831_03990	COG1612	heme a metabolic process
ALT831_03995	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ALT831_03996	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ALT831_03997	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ALT831_04000	COG3706	GGDEF domain
ALT831_04003	COG0129	dihydroxy-acid dehydratase activity
ALT831_04004	COG2860	membrane
ALT831_04005	COG0606	chelatase, subunit chli
ALT831_04006	COG0583	DNA-binding transcription factor activity
ALT831_04008	COG2814	Major facilitator Superfamily
ALT831_04010	COG0729	surface antigen
ALT831_04011	COG2911	Protein conserved in bacteria
ALT831_04016	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALT831_04018	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ALT831_04022	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ALT831_04027	COG1228	amidohydrolase
ALT831_04031	COG0425	Belongs to the sulfur carrier protein TusA family
ALT831_04034	COG1561	YicC-like family, N-terminal region
ALT831_04039	COG2211	Major facilitator Superfamily
ALT831_04040	COG1609	Transcriptional regulator
ALT831_04044	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ALT831_04044	COG2199	diguanylate cyclase activity
ALT831_04049	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ALT831_04053	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ALT831_04054	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ALT831_04058	COG1475	DNA binding
ALT831_04059	COG1192	Involved in chromosome partitioning
ALT831_04064	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ALT831_04065	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ALT831_04067	COG0706	membrane insertase activity
ALT831_04068	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ALT831_04069	COG0594	ribonuclease P activity
ALT831_04070	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ALT831_04074	COG2207	Transcriptional regulator
ALT831_04074	COG1917	Cupin 2, conserved barrel domain protein
ALT831_04075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ALT831_04076	COG1280	lysine exporter protein (LysE YggA)
ALT831_04077	COG1522	sequence-specific DNA binding
ALT831_04086	COG1396	sequence-specific DNA binding
ALT831_04087	COG3550	peptidyl-serine autophosphorylation
ALT831_04105	COG1192	Involved in chromosome partitioning
ALT831_04116	COG5002	protein histidine kinase activity
ALT831_04117	COG0745	RESPONSE REGULATOR receiver
ALT831_04122	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALT831_04139	COG1017	nitric oxide dioxygenase activity
ALT831_04139	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ALT831_04143	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ALT831_04149	COG0375	protein maturation
ALT831_04151	COG0409	Hydrogenase expression formation protein
ALT831_04153	COG0309	Hydrogenase expression formation protein (HypE)
ALT831_04154	COG0789	Transcriptional regulator
ALT831_04155	COG2217	Heavy metal translocating P-type atpase
ALT831_04173	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ALT831_04175	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ALT831_04177	COG0463	Glycosyl transferase, family 2
ALT831_04178	COG0745	RESPONSE REGULATOR receiver
ALT831_04179	COG5002	protein histidine kinase activity
ALT831_04186	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ALT831_04188	COG0789	Transcriptional regulator
ALT831_04189	COG2217	Heavy metal translocating P-type atpase
ALT831_04196	COG0531	amino acid
ALT831_04203	COG3209	COG3209 Rhs family protein
ALT831_04205	COG0789	Transcriptional regulator