locus-tag	class	description
MIT1002_00003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MIT1002_00008	COG2818	Glycosylase
MIT1002_00010	COG3078	GTPase activator activity
MIT1002_00014	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIT1002_00014	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIT1002_00015	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
MIT1002_00016	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MIT1002_00017	COG0569	domain protein
MIT1002_00018	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIT1002_00018	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MIT1002_00019	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MIT1002_00022	COG0758	DNA mediated transformation
MIT1002_00025	COG0009	L-threonylcarbamoyladenylate synthase
MIT1002_00026	COG0408	coproporphyrinogen oxidase activity
MIT1002_00027	COG3047	cAMP biosynthetic process
MIT1002_00030	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MIT1002_00046	COG2234	aminopeptidase activity
MIT1002_00048	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MIT1002_00053	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MIT1002_00059	COG3642	lipopolysaccharide core region biosynthetic process
MIT1002_00065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIT1002_00068	COG3161	chorismate lyase activity
MIT1002_00069	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MIT1002_00071	COG0210	DNA helicase
MIT1002_00077	COG1757	Na H antiporter
MIT1002_00078	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MIT1002_00087	COG0583	DNA-binding transcription factor activity
MIT1002_00089	COG3106	COG3106 Predicted ATPase
MIT1002_00092	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MIT1002_00096	COG0352	thiamine-phosphate diphosphorylase activity
MIT1002_00099	COG3071	HemY protein
MIT1002_00100	COG2959	enzyme of heme biosynthesis
MIT1002_00102	COG0181	hydroxymethylbilane synthase activity
MIT1002_00106	COG0194	GDP metabolic process
MIT1002_00108	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIT1002_00110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIT1002_00111	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MIT1002_00113	COG0678	peroxiredoxin activity
MIT1002_00116	COG1178	ABC-type Fe3 transport system permease component
MIT1002_00117	COG3842	ATPase activity
MIT1002_00118	COG2081	HI0933 family
MIT1002_00124	COG3047	cAMP biosynthetic process
MIT1002_00127	COG2200	EAL domain
MIT1002_00128	COG3706	GGDEF domain
MIT1002_00134	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_00137	COG0427	acetyl-CoA hydrolase
MIT1002_00138	COG0123	including yeast histone deacetylase and acetoin utilization protein
MIT1002_00141	COG0840	transmembrane signaling receptor activity
MIT1002_00143	COG3064	Membrane
MIT1002_00145	COG5002	protein histidine kinase activity
MIT1002_00145	COG5001	Diguanylate cyclase
MIT1002_00148	COG0514	ATP-dependent DNA helicase (RecQ)
MIT1002_00149	COG2050	protein possibly involved in aromatic compounds catabolism
MIT1002_00150	COG2239	Acts as a magnesium transporter
MIT1002_00151	COG2962	Rard protein
MIT1002_00152	COG3706	GGDEF domain
MIT1002_00153	COG0210	DNA helicase
MIT1002_00155	COG3706	GGDEF domain
MIT1002_00156	COG1011	Hydrolase
MIT1002_00157	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MIT1002_00159	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MIT1002_00160	COG0019	diaminopimelate decarboxylase activity
MIT1002_00167	COG0163	prenyltransferase activity
MIT1002_00168	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MIT1002_00170	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MIT1002_00177	COG1077	Cell shape determining protein MreB Mrl
MIT1002_00179	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MIT1002_00180	COG2814	Major facilitator Superfamily
MIT1002_00181	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MIT1002_00185	COG3385	transposase activity
MIT1002_00189	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MIT1002_00191	COG0629	single-stranded DNA binding
MIT1002_00195	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIT1002_00197	COG3385	transposase activity
MIT1002_00199	COG1349	DNA-binding transcription factor activity
MIT1002_00208	COG3267	Type II secretory pathway component ExeA
MIT1002_00208	COG3409	Peptidoglycan-binding domain 1 protein
MIT1002_00210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MIT1002_00211	COG1459	type II secretion system
MIT1002_00213	COG2165	general secretion pathway protein
MIT1002_00220	COG1077	Cell shape determining protein MreB Mrl
MIT1002_00221	COG1792	Involved in formation and maintenance of cell shape
MIT1002_00222	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MIT1002_00224	COG1530	ribonuclease E activity
MIT1002_00226	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIT1002_00227	COG0312	modulator of DNA gyrase
MIT1002_00229	COG3028	Belongs to the UPF0307 family
MIT1002_00230	COG0312	modulator of DNA gyrase
MIT1002_00233	COG0745	RESPONSE REGULATOR receiver
MIT1002_00234	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIT1002_00234	COG4191	Histidine kinase
MIT1002_00235	COG0297	glycogen (starch) synthase activity
MIT1002_00237	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MIT1002_00244	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MIT1002_00246	COG5002	protein histidine kinase activity
MIT1002_00247	COG0745	RESPONSE REGULATOR receiver
MIT1002_00252	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIT1002_00268	COG1017	nitric oxide dioxygenase activity
MIT1002_00268	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MIT1002_00272	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MIT1002_00278	COG0375	protein maturation
MIT1002_00280	COG0409	Hydrogenase expression formation protein
MIT1002_00282	COG0309	Hydrogenase expression formation protein (HypE)
MIT1002_00283	COG0789	Transcriptional regulator
MIT1002_00284	COG2217	Heavy metal translocating P-type atpase
MIT1002_00301	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MIT1002_00303	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MIT1002_00305	COG0463	Glycosyl transferase, family 2
MIT1002_00307	COG0745	RESPONSE REGULATOR receiver
MIT1002_00308	COG5002	protein histidine kinase activity
MIT1002_00315	COG0501	Belongs to the peptidase M48B family
MIT1002_00318	COG4372	Transposase
MIT1002_00322	COG1484	DNA-dependent DNA replication
MIT1002_00323	COG4584	PFAM Integrase catalytic
MIT1002_00327	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MIT1002_00329	COG0789	Transcriptional regulator
MIT1002_00330	COG2217	Heavy metal translocating P-type atpase
MIT1002_00337	COG0531	amino acid
MIT1002_00348	COG3385	transposase activity
MIT1002_00356	COG0546	phosphoglycolate phosphatase activity
MIT1002_00363	COG1609	Transcriptional regulator
MIT1002_00364	COG0673	inositol 2-dehydrogenase activity
MIT1002_00366	COG2211	Major facilitator Superfamily
MIT1002_00371	COG1454	alcohol dehydrogenase
MIT1002_00382	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MIT1002_00386	COG0089	rRNA binding
MIT1002_00388	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MIT1002_00390	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MIT1002_00393	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MIT1002_00395	COG1519	Transferase
MIT1002_00404	COG0788	formyltetrahydrofolate deformylase activity
MIT1002_00406	COG1643	Atp-dependent helicase
MIT1002_00408	COG2951	lytic endotransglycosylase activity
MIT1002_00409	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MIT1002_00412	COG2354	Protein conserved in bacteria
MIT1002_00417	COG0004	ammonium transporteR
MIT1002_00418	COG3385	transposase activity
MIT1002_00419	COG0405	Gamma-glutamyltransferase
MIT1002_00420	COG2837	iron assimilation
MIT1002_00423	COG0540	Belongs to the ATCase OTCase family
MIT1002_00430	COG5002	protein histidine kinase activity
MIT1002_00430	COG2205	protein histidine kinase activity
MIT1002_00430	COG0784	Response regulator, receiver
MIT1002_00433	COG5001	Diguanylate cyclase
MIT1002_00433	COG3300	MHYT domain
MIT1002_00435	COG1012	belongs to the aldehyde dehydrogenase family
MIT1002_00437	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MIT1002_00439	COG0512	Glutamine amidotransferase of anthranilate synthase
MIT1002_00440	COG0180	Tryptophanyl-tRNA synthetase
MIT1002_00441	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MIT1002_00445	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MIT1002_00447	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MIT1002_00454	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MIT1002_00455	COG0281	malic enzyme
MIT1002_00457	COG0625	glutathione transferase activity
MIT1002_00461	COG0753	catalase activity
MIT1002_00466	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MIT1002_00466	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MIT1002_00468	COG0137	argininosuccinate synthase activity
MIT1002_00472	COG1803	Methylglyoxal synthase
MIT1002_00474	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MIT1002_00477	COG0745	RESPONSE REGULATOR receiver
MIT1002_00478	COG2205	protein histidine kinase activity
MIT1002_00479	COG2267	carboxylic ester hydrolase activity
MIT1002_00480	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MIT1002_00481	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_00482	COG1136	(ABC) transporter
MIT1002_00482	COG0577	efflux transmembrane transporter activity
MIT1002_00485	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MIT1002_00487	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MIT1002_00488	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIT1002_00489	COG4942	peptidase
MIT1002_00490	COG2861	carbohydrate metabolic process
MIT1002_00492	COG0584	glycerophosphoryl diester phosphodiesterase
MIT1002_00495	COG1162	GTPase activity
MIT1002_00496	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MIT1002_00499	COG4771	TonB-dependent receptor
MIT1002_00500	COG0457	Tetratricopeptide repeat
MIT1002_00503	COG0028	Belongs to the TPP enzyme family
MIT1002_00507	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MIT1002_00508	COG0805	protein transport
MIT1002_00510	COG0084	hydrolase, TatD family'
MIT1002_00511	COG5001	Diguanylate cyclase
MIT1002_00511	COG2203	Gaf domain
MIT1002_00511	COG4251	negative regulation of phosphorylation
MIT1002_00511	COG3706	GGDEF domain
MIT1002_00513	COG3385	transposase activity
MIT1002_00514	COG0248	Ppx GppA phosphatase
MIT1002_00515	COG0513	Belongs to the DEAD box helicase family
MIT1002_00516	COG3118	belongs to the thioredoxin family
MIT1002_00517	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MIT1002_00518	COG1473	amidohydrolase
MIT1002_00519	COG2205	protein histidine kinase activity
MIT1002_00519	COG0784	Response regulator, receiver
MIT1002_00520	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MIT1002_00521	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MIT1002_00522	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MIT1002_00525	COG0783	Belongs to the Dps family
MIT1002_00526	COG2133	pyrroloquinoline quinone binding
MIT1002_00527	COG0823	Involved in the tonB-independent uptake of proteins
MIT1002_00527	COG1506	peptidase
MIT1002_00527	COG4946	Tricorn protease homolog
MIT1002_00529	COG3118	belongs to the thioredoxin family
MIT1002_00532	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
MIT1002_00534	COG1012	belongs to the aldehyde dehydrogenase family
MIT1002_00539	COG1757	Na H antiporter
MIT1002_00542	COG3876	Protein conserved in bacteria
MIT1002_00543	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MIT1002_00547	COG0346	lactoylglutathione lyase activity
MIT1002_00553	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MIT1002_00555	COG2824	Alkylphosphonate utilization operon protein PhnA
MIT1002_00556	COG0454	-acetyltransferase
MIT1002_00558	COG1742	UPF0060 membrane protein
MIT1002_00562	COG3878	Protein conserved in bacteria
MIT1002_00568	COG3344	reverse transcriptase
MIT1002_00571	COG3344	reverse transcriptase
MIT1002_00574	COG0183	Belongs to the thiolase family
MIT1002_00575	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIT1002_00575	COG1024	Enoyl-CoA hydratase
MIT1002_00576	COG0739	heme binding
MIT1002_00576	COG1196	nuclear chromosome segregation
MIT1002_00576	COG0741	lytic transglycosylase activity
MIT1002_00577	COG0006	proline dipeptidase activity
MIT1002_00579	COG0142	geranyltranstransferase activity
MIT1002_00585	COG1061	Type III restriction enzyme res subunit
MIT1002_00626	COG1388	LysM domain
MIT1002_00626	COG4942	peptidase
MIT1002_00627	COG1238	metal cluster binding
MIT1002_00629	COG0585	pseudouridine synthase activity
MIT1002_00630	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MIT1002_00632	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MIT1002_00634	COG0840	transmembrane signaling receptor activity
MIT1002_00635	COG1522	sequence-specific DNA binding
MIT1002_00637	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MIT1002_00637	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MIT1002_00637	COG0506	proline dehydrogenase activity
MIT1002_00640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIT1002_00647	COG0494	nUDIX hydrolase
MIT1002_00648	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
MIT1002_00649	COG0730	response to heat
MIT1002_00650	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MIT1002_00651	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MIT1002_00653	COG3706	GGDEF domain
MIT1002_00654	COG3850	Histidine kinase
MIT1002_00654	COG2205	protein histidine kinase activity
MIT1002_00654	COG3437	response regulator, receiver
MIT1002_00654	COG4999	Histidine kinase
MIT1002_00655	COG2211	Major facilitator Superfamily
MIT1002_00659	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MIT1002_00661	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MIT1002_00662	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MIT1002_00665	COG1648	precorrin-2 dehydrogenase activity
MIT1002_00665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MIT1002_00666	COG0513	Belongs to the DEAD box helicase family
MIT1002_00670	COG1538	Outer membrane efflux protein
MIT1002_00671	COG0494	nUDIX hydrolase
MIT1002_00673	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MIT1002_00674	COG3150	esterase
MIT1002_00677	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MIT1002_00681	COG1509	lysine 2,3-aminomutase activity
MIT1002_00682	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MIT1002_00688	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIT1002_00691	COG0271	Belongs to the BolA IbaG family
MIT1002_00694	COG3707	response regulator
MIT1002_00697	COG0659	secondary active sulfate transmembrane transporter activity
MIT1002_00698	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MIT1002_00699	COG2146	nitrite reductase [NAD(P)H] activity
MIT1002_00700	COG0243	molybdopterin cofactor binding
MIT1002_00701	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MIT1002_00701	COG1648	precorrin-2 dehydrogenase activity
MIT1002_00702	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MIT1002_00705	COG0737	Belongs to the 5'-nucleotidase family
MIT1002_00706	COG4251	negative regulation of phosphorylation
MIT1002_00706	COG5001	Diguanylate cyclase
MIT1002_00706	COG2203	Gaf domain
MIT1002_00706	COG3706	GGDEF domain
MIT1002_00709	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MIT1002_00709	COG1116	anion transmembrane transporter activity
MIT1002_00711	COG1116	anion transmembrane transporter activity
MIT1002_00714	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MIT1002_00716	COG4206	TonB-dependent receptor
MIT1002_00718	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MIT1002_00719	COG0348	domain, Protein
MIT1002_00722	COG1960	acyl-CoA dehydrogenase activity
MIT1002_00723	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_00725	COG4948	Mandelate Racemase Muconate Lactonizing
MIT1002_00728	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_00729	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIT1002_00733	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIT1002_00734	COG0358	DNA primase activity
MIT1002_00740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MIT1002_00741	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MIT1002_00744	COG0537	adenosine 5'-monophosphoramidase activity
MIT1002_00747	COG3135	benzoate transporter
MIT1002_00748	COG1396	sequence-specific DNA binding
MIT1002_00749	COG2974	May be involved in recombination
MIT1002_00750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIT1002_00750	COG4191	Histidine kinase
MIT1002_00751	COG0745	RESPONSE REGULATOR receiver
MIT1002_00752	COG5002	protein histidine kinase activity
MIT1002_00758	COG0811	peptide transport
MIT1002_00759	COG0811	peptide transport
MIT1002_00760	COG0848	biopolymer transport protein
MIT1002_00761	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MIT1002_00763	COG3437	response regulator, receiver
MIT1002_00767	COG2133	pyrroloquinoline quinone binding
MIT1002_00768	COG1049	propionate catabolic process, 2-methylcitrate cycle
MIT1002_00776	COG0527	aspartate kinase activity
MIT1002_00778	COG0840	transmembrane signaling receptor activity
MIT1002_00779	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MIT1002_00780	COG2967	ApaG domain
MIT1002_00782	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MIT1002_00783	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIT1002_00784	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MIT1002_00785	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MIT1002_00787	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MIT1002_00791	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MIT1002_00794	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIT1002_00795	COG3956	TIGRFAM MazG family protein
MIT1002_00799	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_00801	COG0318	PFAM AMP-dependent synthetase and ligase
MIT1002_00803	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MIT1002_00805	COG0463	Glycosyl transferase, family 2
MIT1002_00809	COG0642	Histidine kinase
MIT1002_00813	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MIT1002_00814	COG0723	plastoquinol--plastocyanin reductase activity
MIT1002_00815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MIT1002_00816	COG2857	Cytochrome c1
MIT1002_00817	COG0625	glutathione transferase activity
MIT1002_00818	COG2969	positive regulation of protein catabolic process
MIT1002_00821	COG0745	RESPONSE REGULATOR receiver
MIT1002_00822	COG2239	Acts as a magnesium transporter
MIT1002_00823	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MIT1002_00827	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MIT1002_00828	COG1137	ATPase activity
MIT1002_00829	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MIT1002_00831	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MIT1002_00834	COG1127	ABC transporter
MIT1002_00835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MIT1002_00836	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MIT1002_00837	COG2854	intermembrane phospholipid transfer
MIT1002_00839	COG5007	Belongs to the BolA IbaG family
MIT1002_00841	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIT1002_00842	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIT1002_00844	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MIT1002_00849	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIT1002_00853	COG4771	TonB-dependent receptor
MIT1002_00854	COG0697	spore germination
MIT1002_00856	COG0784	Response regulator, receiver
MIT1002_00856	COG2205	protein histidine kinase activity
MIT1002_00861	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MIT1002_00863	COG0126	phosphoglycerate kinase activity
MIT1002_00864	COG3588	fructose-bisphosphate aldolase
MIT1002_00868	COG1538	Outer membrane efflux protein
MIT1002_00870	COG0823	Involved in the tonB-independent uptake of proteins
MIT1002_00870	COG4946	Tricorn protease homolog
MIT1002_00870	COG1506	peptidase
MIT1002_00871	COG0248	Ppx GppA phosphatase
MIT1002_00872	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MIT1002_00874	COG0573	inorganic phosphate transmembrane transporter activity
MIT1002_00876	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MIT1002_00878	COG0306	phosphate transporter
MIT1002_00881	COG0583	DNA-binding transcription factor activity
MIT1002_00886	COG1272	protein, Hemolysin III
MIT1002_00888	COG1846	Transcriptional regulator
MIT1002_00889	COG1764	response to oxidative stress
MIT1002_00893	COG1739	Uncharacterized protein family UPF0029
MIT1002_00897	COG0420	3'-5' exonuclease activity
MIT1002_00898	COG0419	ATPase involved in DNA repair
MIT1002_00900	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MIT1002_00904	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MIT1002_00905	COG2986	histidine ammonia-lyase
MIT1002_00909	COG2971	BadF BadG BcrA BcrD
MIT1002_00910	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MIT1002_00912	COG0488	(ABC) transporter
MIT1002_00915	COG0668	transmembrane transport
MIT1002_00918	COG4771	TonB-dependent receptor
MIT1002_00919	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_00920	COG0842	Transport permease protein
MIT1002_00920	COG1129	ABC transporter
MIT1002_00921	COG0842	Transport permease protein
MIT1002_00923	COG2814	Major facilitator Superfamily
MIT1002_00933	COG1346	cytolysis
MIT1002_00939	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MIT1002_00940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MIT1002_00941	COG0513	Belongs to the DEAD box helicase family
MIT1002_00943	COG3409	Peptidoglycan-binding domain 1 protein
MIT1002_00943	COG3267	Type II secretory pathway component ExeA
MIT1002_00948	COG0473	3-isopropylmalate dehydrogenase activity
MIT1002_00949	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIT1002_00953	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MIT1002_00956	COG4555	ABC transporter
MIT1002_00957	COG1668	transmembrane transport
MIT1002_00960	COG4133	protoheme IX ABC transporter activity
MIT1002_00961	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MIT1002_00962	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MIT1002_00963	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MIT1002_00965	COG1138	Cytochrome C-type biogenesis protein
MIT1002_00969	COG2853	Lipoprotein
MIT1002_00970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MIT1002_00978	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MIT1002_00981	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MIT1002_00982	COG1555	photosystem II stabilization
MIT1002_00982	COG1596	polysaccharide export
MIT1002_00983	COG0473	3-isopropylmalate dehydrogenase activity
MIT1002_00986	COG1611	Belongs to the LOG family
MIT1002_00994	COG0071	Belongs to the small heat shock protein (HSP20) family
MIT1002_00998	COG0564	pseudouridine synthase activity
MIT1002_01001	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MIT1002_01002	COG0024	Methionine aminopeptidase
MIT1002_01004	COG0052	Belongs to the universal ribosomal protein uS2 family
MIT1002_01006	COG0528	UMP kinase activity
MIT1002_01009	COG0575	Belongs to the CDS family
MIT1002_01014	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MIT1002_01015	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIT1002_01018	COG0587	DNA-directed DNA polymerase activity
MIT1002_01019	COG0825	malonyl-CoA metabolic process
MIT1002_01020	COG0037	tRNA processing
MIT1002_01027	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MIT1002_01027	COG0047	phosphoribosylformylglycinamidine synthase activity
MIT1002_01029	COG2840	Smr protein MutS2
MIT1002_01037	COG0784	Response regulator, receiver
MIT1002_01037	COG0835	chemotaxis
MIT1002_01038	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MIT1002_01039	COG1815	bacterial-type flagellum-dependent cell motility
MIT1002_01042	COG1749	Flagellar hook protein flgE
MIT1002_01043	COG4787	bacterial-type flagellum-dependent cell motility
MIT1002_01044	COG4786	Flagellar basal body rod
MIT1002_01049	COG3951	Flagellar rod assembly protein muramidase FlgJ
MIT1002_01049	COG1705	Flagellar rod assembly protein muramidase FlgJ
MIT1002_01050	COG1256	bacterial-type flagellum assembly
MIT1002_01053	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MIT1002_01054	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MIT1002_01061	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MIT1002_01065	COG2963	transposase activity
MIT1002_01067	COG2801	Transposase and inactivated derivatives
MIT1002_01068	COG2826	transposase and inactivated derivatives, IS30 family
MIT1002_01069	COG2826	transposase and inactivated derivatives, IS30 family
MIT1002_01070	COG2826	transposase and inactivated derivatives, IS30 family
MIT1002_01071	COG2963	transposase activity
MIT1002_01072	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MIT1002_01073	COG2089	acid synthase
MIT1002_01077	COG1083	cytidylyl-transferase
MIT1002_01078	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MIT1002_01079	COG1086	Polysaccharide biosynthesis protein
MIT1002_01084	COG1677	Flagellar hook-basal body complex protein FliE
MIT1002_01085	COG1766	The M ring may be actively involved in energy transduction
MIT1002_01086	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MIT1002_01096	COG1987	bacterial-type flagellum assembly
MIT1002_01100	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MIT1002_01105	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
MIT1002_01106	COG0784	Response regulator, receiver
MIT1002_01106	COG0643	Histidine kinase
MIT1002_01106	COG2198	Histidine kinase
MIT1002_01107	COG2201	protein-glutamate methylesterase activity
MIT1002_01108	COG1192	Involved in chromosome partitioning
MIT1002_01110	COG0835	chemotaxis
MIT1002_01113	COG0646	methionine synthase
MIT1002_01113	COG1410	methionine synthase
MIT1002_01114	COG1410	methionine synthase
MIT1002_01114	COG0646	methionine synthase
MIT1002_01116	COG3123	guanosine phosphorylase activity
MIT1002_01119	COG0583	DNA-binding transcription factor activity
MIT1002_01120	COG0583	DNA-binding transcription factor activity
MIT1002_01121	COG0288	reversible hydration of carbon dioxide
MIT1002_01122	COG0659	secondary active sulfate transmembrane transporter activity
MIT1002_01124	COG1309	transcriptional regulator
MIT1002_01125	COG3590	peptidase
MIT1002_01127	COG2137	regulation of response to DNA damage stimulus
MIT1002_01128	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MIT1002_01135	COG0511	ligase activity, forming carbon-carbon bonds
MIT1002_01135	COG5016	pyruvate
MIT1002_01136	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
MIT1002_01137	COG4172	Belongs to the ABC transporter superfamily
MIT1002_01139	COG4171	peptide transport system, permease
MIT1002_01140	COG4168	peptide transport system, permease
MIT1002_01141	COG0747	negative chemotaxis
MIT1002_01142	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MIT1002_01143	COG1842	Phage shock protein A
MIT1002_01149	COG0625	glutathione transferase activity
MIT1002_01150	COG1522	sequence-specific DNA binding
MIT1002_01156	COG0457	Tetratricopeptide repeat
MIT1002_01164	COG0811	peptide transport
MIT1002_01165	COG0811	peptide transport
MIT1002_01166	COG0848	biopolymer transport protein
MIT1002_01169	COG1444	tRNA N-acetyltransferase activity
MIT1002_01178	COG0456	acetyltransferase
MIT1002_01180	COG0583	DNA-binding transcription factor activity
MIT1002_01181	COG2814	Major facilitator Superfamily
MIT1002_01184	COG3547	Transposase (IS116 IS110 IS902 family)
MIT1002_01188	COG1846	Transcriptional regulator
MIT1002_01190	COG3275	phosphorelay sensor kinase activity
MIT1002_01191	COG1966	Carbon starvation protein
MIT1002_01195	COG0457	Tetratricopeptide repeat
MIT1002_01198	COG2197	response regulator
MIT1002_01201	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MIT1002_01208	COG0583	DNA-binding transcription factor activity
MIT1002_01209	COG0702	epimerase
MIT1002_01213	COG1902	pentaerythritol trinitrate reductase activity
MIT1002_01216	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MIT1002_01217	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MIT1002_01219	COG0564	pseudouridine synthase activity
MIT1002_01221	COG0612	Peptidase, M16
MIT1002_01222	COG2918	glutathione biosynthetic process
MIT1002_01227	COG2840	Smr protein MutS2
MIT1002_01228	COG2890	protein-(glutamine-N5) methyltransferase activity
MIT1002_01231	COG2719	SpoVR family
MIT1002_01232	COG2718	Belongs to the UPF0229 family
MIT1002_01233	COG2766	serine protein kinase
MIT1002_01234	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MIT1002_01235	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MIT1002_01236	COG4771	TonB-dependent receptor
MIT1002_01241	COG0450	alkyl hydroperoxide reductase
MIT1002_01242	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MIT1002_01243	COG2885	chlorophyll binding
MIT1002_01244	COG0584	glycerophosphoryl diester phosphodiesterase
MIT1002_01245	COG0346	lactoylglutathione lyase activity
MIT1002_01246	COG4221	oxidoreductase activity
MIT1002_01248	COG1278	Cold shock
MIT1002_01251	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MIT1002_01252	COG4660	Part of a membrane complex involved in electron transport
MIT1002_01253	COG4659	FMN binding
MIT1002_01254	COG4658	electron transport chain
MIT1002_01255	COG4656	Part of a membrane complex involved in electron transport
MIT1002_01256	COG2878	Part of a membrane complex involved in electron transport
MIT1002_01257	COG4657	Part of a membrane complex involved in electron transport
MIT1002_01260	COG0534	Mate efflux family protein
MIT1002_01261	COG0556	nucleotide-excision repair
MIT1002_01264	COG0602	queuosine metabolic process
MIT1002_01266	COG0367	asparagine synthase
MIT1002_01270	COG0471	metal ion transport
MIT1002_01270	COG3273	potassium ion transport
MIT1002_01273	COG0529	Catalyzes the synthesis of activated sulfate
MIT1002_01274	COG0175	sulfate reduction
MIT1002_01275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIT1002_01281	COG2304	oxidoreductase activity
MIT1002_01285	COG0714	Associated with various cellular activities
MIT1002_01287	COG1024	Enoyl-CoA hydratase
MIT1002_01287	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIT1002_01291	COG1025	Belongs to the peptidase M16 family
MIT1002_01292	COG2062	phosphohistidine phosphatase, SixA
MIT1002_01294	COG4536	flavin adenine dinucleotide binding
MIT1002_01295	COG4137	Cytochrome C assembly protein
MIT1002_01296	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MIT1002_01304	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_01305	COG1132	(ABC) transporter
MIT1002_01308	COG0228	four-way junction DNA binding
MIT1002_01309	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MIT1002_01310	COG0336	Belongs to the RNA methyltransferase TrmD family
MIT1002_01311	COG0335	large ribosomal subunit rRNA binding
MIT1002_01312	COG2860	membrane
MIT1002_01314	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIT1002_01315	COG0287	Prephenate dehydrogenase
MIT1002_01315	COG1605	Chorismate mutase
MIT1002_01316	COG1605	Chorismate mutase
MIT1002_01316	COG0077	Prephenate dehydratase
MIT1002_01317	COG0745	RESPONSE REGULATOR receiver
MIT1002_01318	COG0023	Translation Initiation Factor
MIT1002_01324	COG2205	protein histidine kinase activity
MIT1002_01326	COG2204	response regulator
MIT1002_01329	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MIT1002_01330	COG0494	nUDIX hydrolase
MIT1002_01331	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MIT1002_01332	COG0632	four-way junction helicase activity
MIT1002_01333	COG2255	four-way junction helicase activity
MIT1002_01334	COG0824	Thioesterase
MIT1002_01335	COG0811	peptide transport
MIT1002_01338	COG0823	Involved in the tonB-independent uptake of proteins
MIT1002_01339	COG2885	chlorophyll binding
MIT1002_01340	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
MIT1002_01344	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MIT1002_01347	COG4667	esterase of the alpha-beta hydrolase superfamily
MIT1002_01348	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MIT1002_01350	COG0784	Response regulator, receiver
MIT1002_01350	COG2205	protein histidine kinase activity
MIT1002_01353	COG3038	cytochrome b561
MIT1002_01357	COG1451	nucleotide metabolic process
MIT1002_01359	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIT1002_01361	COG1309	transcriptional regulator
MIT1002_01362	COG4774	siderophore transport
MIT1002_01366	COG3706	GGDEF domain
MIT1002_01368	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MIT1002_01368	COG3008	intermembrane lipid transfer
MIT1002_01369	COG2995	paraquat-inducible protein a
MIT1002_01371	COG0017	Asparaginyl-tRNA synthetase
MIT1002_01374	COG0189	ligase activity
MIT1002_01381	COG2226	methyltransferase
MIT1002_01383	COG3340	Belongs to the peptidase S51 family
MIT1002_01384	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MIT1002_01385	COG4139	cobalamin transport
MIT1002_01386	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
MIT1002_01387	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MIT1002_01388	COG2205	protein histidine kinase activity
MIT1002_01389	COG0745	RESPONSE REGULATOR receiver
MIT1002_01390	COG0569	domain protein
MIT1002_01391	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MIT1002_01394	COG5265	(ABC) transporter
MIT1002_01395	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MIT1002_01397	COG0745	RESPONSE REGULATOR receiver
MIT1002_01402	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIT1002_01411	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIT1002_01414	COG2755	lipolytic protein G-D-S-L family
MIT1002_01415	COG4181	ATPase activity
MIT1002_01416	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MIT1002_01417	COG1090	epimerase
MIT1002_01418	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MIT1002_01419	COG0628	permease
MIT1002_01424	COG2350	Protein conserved in bacteria
MIT1002_01425	COG0159	tryptophan synthase activity
MIT1002_01427	COG0134	indole-3-glycerol-phosphate synthase activity
MIT1002_01427	COG0135	phosphoribosylanthranilate isomerase activity
MIT1002_01428	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MIT1002_01430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MIT1002_01431	COG0613	PHP domain protein
MIT1002_01432	COG0009	L-threonylcarbamoyladenylate synthase
MIT1002_01434	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MIT1002_01436	COG0656	L-ascorbic acid biosynthetic process
MIT1002_01437	COG0110	maltose O-acetyltransferase activity
MIT1002_01440	COG2733	membrane
MIT1002_01441	COG0500	methyltransferase
MIT1002_01442	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MIT1002_01443	COG0497	DNA recombination
MIT1002_01444	COG0783	Belongs to the Dps family
MIT1002_01445	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MIT1002_01447	COG1454	alcohol dehydrogenase
MIT1002_01448	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_01450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIT1002_01451	COG2610	gluconate transmembrane transporter activity
MIT1002_01452	COG4771	TonB-dependent receptor
MIT1002_01454	COG2205	protein histidine kinase activity
MIT1002_01454	COG2198	Histidine kinase
MIT1002_01454	COG0784	Response regulator, receiver
MIT1002_01454	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIT1002_01456	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MIT1002_01458	COG0484	heat shock protein binding
MIT1002_01459	COG3909	cytochrome
MIT1002_01462	COG2199	diguanylate cyclase activity
MIT1002_01462	COG2200	EAL domain
MIT1002_01462	COG2202	Pas domain
MIT1002_01465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MIT1002_01467	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MIT1002_01468	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MIT1002_01472	COG0071	Belongs to the small heat shock protein (HSP20) family
MIT1002_01474	COG0280	phosphate acetyltransferase
MIT1002_01474	COG0857	belongs to the CobB CobQ family
MIT1002_01475	COG1228	amidohydrolase
MIT1002_01476	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MIT1002_01477	COG4535	Mg2 and Co2 transporter CorC
MIT1002_01479	COG1702	phosphate starvation-inducible protein PhoH
MIT1002_01481	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIT1002_01491	COG1607	acyl-coa hydrolase
MIT1002_01492	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIT1002_01494	COG1115	amino acid carrier protein
MIT1002_01504	COG0012	GTP binding
MIT1002_01507	COG1064	alcohol dehydrogenase
MIT1002_01509	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIT1002_01511	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MIT1002_01512	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MIT1002_01513	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MIT1002_01515	COG2890	protein-(glutamine-N5) methyltransferase activity
MIT1002_01516	COG0784	Response regulator, receiver
MIT1002_01516	COG3437	response regulator, receiver
MIT1002_01518	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MIT1002_01520	COG0583	DNA-binding transcription factor activity
MIT1002_01522	COG2363	Small membrane protein
MIT1002_01527	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MIT1002_01528	COG0515	serine threonine protein kinase
MIT1002_01529	COG2116	formate transmembrane transporter activity
MIT1002_01532	COG0714	Associated with various cellular activities
MIT1002_01533	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
MIT1002_01534	COG0033	Phosphoglucomutase
MIT1002_01535	COG0058	SHG alpha-glucan phosphorylase activity
MIT1002_01538	COG2988	succinylglutamate desuccinylase activity
MIT1002_01541	COG1506	peptidase
MIT1002_01542	COG1301	dicarboxylic acid transport
MIT1002_01546	COG1393	Belongs to the ArsC family
MIT1002_01549	COG1484	DNA-dependent DNA replication
MIT1002_01550	COG4584	PFAM Integrase catalytic
MIT1002_01554	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MIT1002_01558	COG3300	MHYT domain
MIT1002_01558	COG5001	Diguanylate cyclase
MIT1002_01561	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIT1002_01564	COG2249	NAD(P)H dehydrogenase (quinone) activity
MIT1002_01566	COG1733	regulation of RNA biosynthetic process
MIT1002_01568	COG3447	MASE1 domain protein
MIT1002_01568	COG5001	Diguanylate cyclase
MIT1002_01568	COG5002	protein histidine kinase activity
MIT1002_01570	COG0402	S-adenosylhomocysteine deaminase activity
MIT1002_01574	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MIT1002_01576	COG1309	transcriptional regulator
MIT1002_01579	COG2252	PERMEase
MIT1002_01580	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MIT1002_01585	COG2205	protein histidine kinase activity
MIT1002_01585	COG0784	Response regulator, receiver
MIT1002_01588	COG2233	PERMEase
MIT1002_01592	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MIT1002_01593	COG0730	response to heat
MIT1002_01595	COG0154	amidase activity
MIT1002_01601	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_01602	COG3001	Fructosamine kinase
MIT1002_01604	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MIT1002_01607	COG0662	Cupin 2, conserved barrel domain protein
MIT1002_01607	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MIT1002_01608	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MIT1002_01611	COG1596	polysaccharide export
MIT1002_01612	COG0489	protein tyrosine kinase activity
MIT1002_01613	COG4464	protein tyrosine phosphatase activity
MIT1002_01620	COG0438	transferase activity, transferring glycosyl groups
MIT1002_01623	COG1215	transferase activity, transferring glycosyl groups
MIT1002_01624	COG1216	Glycosyl transferase, family 2
MIT1002_01631	COG2246	polysaccharide biosynthetic process
MIT1002_01632	COG0463	Glycosyl transferase, family 2
MIT1002_01634	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MIT1002_01634	COG2755	lipolytic protein G-D-S-L family
MIT1002_01637	COG0072	phenylalanine-tRNA ligase activity
MIT1002_01637	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIT1002_01643	COG1472	Belongs to the glycosyl hydrolase 3 family
MIT1002_01644	COG2096	Adenosyltransferase
MIT1002_01646	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MIT1002_01648	COG4591	ABC-type transport system involved in lipoprotein release permease component
MIT1002_01652	COG0708	Exodeoxyribonuclease III
MIT1002_01659	COG2814	Major facilitator Superfamily
MIT1002_01666	COG4770	biotin carboxylase activity
MIT1002_01667	COG1024	Enoyl-CoA hydratase
MIT1002_01668	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MIT1002_01669	COG1960	acyl-CoA dehydrogenase activity
MIT1002_01670	COG0789	Transcriptional regulator
MIT1002_01671	COG0183	Belongs to the thiolase family
MIT1002_01676	COG2925	Exonuclease
MIT1002_01685	COG1643	Atp-dependent helicase
MIT1002_01689	COG0604	alcohol dehydrogenase
MIT1002_01689	COG3321	synthase
MIT1002_01690	COG0328	RNA-DNA hybrid ribonuclease activity
MIT1002_01691	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MIT1002_01697	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MIT1002_01698	COG1136	(ABC) transporter
MIT1002_01699	COG4591	ABC-type transport system involved in lipoprotein release permease component
MIT1002_01702	COG1301	dicarboxylic acid transport
MIT1002_01704	COG3724	N-succinylarginine dihydrolase activity
MIT1002_01705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MIT1002_01706	COG3122	Protein conserved in bacteria
MIT1002_01710	COG0583	DNA-binding transcription factor activity
MIT1002_01711	COG0746	molybdenum cofactor guanylyltransferase activity
MIT1002_01712	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MIT1002_01713	COG0243	molybdopterin cofactor binding
MIT1002_01715	COG0625	glutathione transferase activity
MIT1002_01718	COG2153	protein acetylation
MIT1002_01722	COG5002	protein histidine kinase activity
MIT1002_01724	COG1530	ribonuclease E activity
MIT1002_01725	COG0564	pseudouridine synthase activity
MIT1002_01726	COG0546	phosphoglycolate phosphatase activity
MIT1002_01727	COG0424	maF-like protein
MIT1002_01728	COG1399	metal-binding, possibly nucleic acid-binding protein
MIT1002_01730	COG0416	fatty acid biosynthetic process
MIT1002_01731	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MIT1002_01732	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MIT1002_01734	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MIT1002_01735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MIT1002_01736	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MIT1002_01737	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIT1002_01740	COG0084	hydrolase, TatD family'
MIT1002_01741	COG0259	pyridoxamine-phosphate oxidase activity
MIT1002_01742	COG0702	epimerase
MIT1002_01743	COG3706	GGDEF domain
MIT1002_01748	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_01749	COG0596	Alpha beta hydrolase
MIT1002_01751	COG0183	Belongs to the thiolase family
MIT1002_01752	COG1960	acyl-CoA dehydrogenase activity
MIT1002_01756	COG2390	Transcriptional regulator
MIT1002_01761	COG0668	transmembrane transport
MIT1002_01762	COG4771	TonB-dependent receptor
MIT1002_01767	COG2205	protein histidine kinase activity
MIT1002_01767	COG2198	Histidine kinase
MIT1002_01767	COG0784	Response regulator, receiver
MIT1002_01768	COG3437	response regulator, receiver
MIT1002_01770	COG0195	Participates in both transcription termination and antitermination
MIT1002_01773	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MIT1002_01776	COG1187	pseudouridine synthase activity
MIT1002_01778	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIT1002_01778	COG3153	acetyltransferase
MIT1002_01793	COG1032	radical SAM domain protein
MIT1002_01798	COG0583	DNA-binding transcription factor activity
MIT1002_01803	COG1131	(ABC) transporter
MIT1002_01805	COG1902	pentaerythritol trinitrate reductase activity
MIT1002_01807	COG2867	negative regulation of translational initiation
MIT1002_01808	COG2914	Belongs to the UPF0125 (RnfH) family
MIT1002_01810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MIT1002_01811	COG4771	TonB-dependent receptor
MIT1002_01812	COG0457	Tetratricopeptide repeat
MIT1002_01816	COG0574	Belongs to the PEP-utilizing enzyme family
MIT1002_01816	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MIT1002_01824	COG2850	peptidyl-arginine hydroxylation
MIT1002_01826	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MIT1002_01827	COG2915	High frequency lysogenization protein hflD homolog
MIT1002_01828	COG0482	sulfurtransferase activity
MIT1002_01829	COG1187	pseudouridine synthase activity
MIT1002_01832	COG1278	Cold shock
MIT1002_01833	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MIT1002_01834	COG0542	response to heat
MIT1002_01835	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MIT1002_01836	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MIT1002_01837	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MIT1002_01838	COG0492	ferredoxin-NADP+ reductase activity
MIT1002_01839	COG3092	negative regulation of chromosome organization
MIT1002_01840	COG0616	signal peptide processing
MIT1002_01842	COG0778	Nitroreductase
MIT1002_01844	COG0252	asparaginase activity
MIT1002_01845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MIT1002_01846	COG0321	lipoyl(octanoyl) transferase activity
MIT1002_01847	COG2921	Belongs to the UPF0250 family
MIT1002_01848	COG1686	Belongs to the peptidase S11 family
MIT1002_01849	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MIT1002_01850	COG0772	Belongs to the SEDS family
MIT1002_01851	COG0768	penicillin binding
MIT1002_01852	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MIT1002_01853	COG0799	negative regulation of ribosome biogenesis
MIT1002_01855	COG1466	dna polymerase III delta subunit
MIT1002_01856	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
MIT1002_01857	COG0495	leucyl-tRNA aminoacylation
MIT1002_01859	COG1067	ATP-dependent peptidase activity
MIT1002_01863	COG1534	Rna-binding protein
MIT1002_01864	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MIT1002_01865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIT1002_01866	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MIT1002_01867	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MIT1002_01868	COG0149	triose-phosphate isomerase activity
MIT1002_01869	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MIT1002_01877	COG1803	Methylglyoxal synthase
MIT1002_01877	COG1597	lipid kinase activity
MIT1002_01879	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_01880	COG0561	phosphatase activity
MIT1002_01883	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIT1002_01884	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIT1002_01885	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MIT1002_01888	COG1185	polyribonucleotide nucleotidyltransferase activity
MIT1002_01893	COG1196	nuclear chromosome segregation
MIT1002_01921	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
MIT1002_01922	COG1196	nuclear chromosome segregation
MIT1002_01924	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MIT1002_01927	COG1132	(ABC) transporter
MIT1002_01928	COG1663	tetraacyldisaccharide 4'-kinase activity
MIT1002_01936	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MIT1002_01937	COG0435	Glutathione S-transferase
MIT1002_01938	COG1741	Belongs to the pirin family
MIT1002_01943	COG0372	Belongs to the citrate synthase family
MIT1002_01945	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MIT1002_01946	COG1053	succinate dehydrogenase
MIT1002_01947	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MIT1002_01948	COG0567	Dehydrogenase, E1 component
MIT1002_01949	COG0508	dehydrogenase complex catalyzes the overall conversion of
MIT1002_01956	COG4667	esterase of the alpha-beta hydrolase superfamily
MIT1002_01960	COG0366	Alpha amylase catalytic
MIT1002_01963	COG1609	Transcriptional regulator
MIT1002_01965	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_01966	COG2267	carboxylic ester hydrolase activity
MIT1002_01967	COG3385	transposase activity
MIT1002_01969	COG0616	signal peptide processing
MIT1002_01972	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MIT1002_01973	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MIT1002_01974	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIT1002_01975	COG0386	Belongs to the glutathione peroxidase family
MIT1002_01976	COG2084	Dehydrogenase
MIT1002_01978	COG1960	acyl-CoA dehydrogenase activity
MIT1002_01979	COG1024	Enoyl-CoA hydratase
MIT1002_01980	COG2226	methyltransferase
MIT1002_01981	COG3083	sulfuric ester hydrolase activity
MIT1002_01982	COG3082	Protein of unknown function (DUF1414)
MIT1002_01983	COG3081	Nucleoid-associated protein
MIT1002_01985	COG0739	heme binding
MIT1002_01985	COG0741	lytic transglycosylase activity
MIT1002_01985	COG1196	nuclear chromosome segregation
MIT1002_01989	COG3275	phosphorelay sensor kinase activity
MIT1002_01990	COG3279	Response regulator of the LytR AlgR family
MIT1002_01991	COG0205	6-phosphofructokinase activity
MIT1002_01993	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIT1002_01993	COG2205	protein histidine kinase activity
MIT1002_01995	COG1054	Belongs to the UPF0176 family
MIT1002_01999	COG0513	Belongs to the DEAD box helicase family
MIT1002_02001	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MIT1002_02002	COG0583	DNA-binding transcription factor activity
MIT1002_02006	COG1760	l-serine dehydratase
MIT1002_02010	COG1322	Protein conserved in bacteria
MIT1002_02011	COG1404	Belongs to the peptidase S8 family
MIT1002_02012	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MIT1002_02013	COG0022	dehydrogenase e1 component
MIT1002_02015	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MIT1002_02016	COG0515	serine threonine protein kinase
MIT1002_02017	COG1946	Acyl-CoA thioesterase
MIT1002_02020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MIT1002_02022	COG1956	GAF domain-containing protein
MIT1002_02025	COG0793	Belongs to the peptidase S41A family
MIT1002_02026	COG0733	neurotransmitter:sodium symporter activity
MIT1002_02027	COG1757	Na H antiporter
MIT1002_02028	COG0308	aminopeptidase N
MIT1002_02034	COG2902	Dehydrogenase
MIT1002_02035	COG0167	dihydroorotate dehydrogenase activity
MIT1002_02038	COG0488	(ABC) transporter
MIT1002_02040	COG3130	regulation of translation
MIT1002_02041	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MIT1002_02043	COG0415	Belongs to the DNA photolyase family
MIT1002_02044	COG0415	Belongs to the DNA photolyase family
MIT1002_02045	COG0415	Belongs to the DNA photolyase family
MIT1002_02046	COG3046	protein related to deoxyribodipyrimidine photolyase
MIT1002_02063	COG0318	PFAM AMP-dependent synthetase and ligase
MIT1002_02065	COG1082	Xylose isomerase domain protein TIM barrel
MIT1002_02071	COG2801	Transposase and inactivated derivatives
MIT1002_02073	COG2205	protein histidine kinase activity
MIT1002_02079	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MIT1002_02104	COG2801	Transposase and inactivated derivatives
MIT1002_02109	COG3621	Patatin-like phospholipase
MIT1002_02117	COG4372	Transposase
MIT1002_02121	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MIT1002_02122	COG0589	response to stress
MIT1002_02124	COG0069	glutamate synthase activity
MIT1002_02127	COG2193	ferroxidase activity
MIT1002_02129	COG3278	Belongs to the heme-copper respiratory oxidase family
MIT1002_02132	COG2010	Cytochrome c
MIT1002_02137	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MIT1002_02138	COG0589	response to stress
MIT1002_02139	COG0037	tRNA processing
MIT1002_02140	COG1752	Esterase of the alpha-beta hydrolase superfamily
MIT1002_02144	COG1280	lysine exporter protein (LysE YggA)
MIT1002_02146	COG2897	thiosulfate sulfurtransferase activity
MIT1002_02147	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MIT1002_02148	COG3148	PFAM DTW domain containing protein
MIT1002_02153	COG0322	excinuclease ABC activity
MIT1002_02154	COG2197	response regulator
MIT1002_02155	COG1741	Belongs to the pirin family
MIT1002_02158	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MIT1002_02162	COG3384	dioxygenase
MIT1002_02163	COG2259	Doxx family
MIT1002_02164	COG0583	DNA-binding transcription factor activity
MIT1002_02167	COG0670	Belongs to the BI1 family
MIT1002_02168	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MIT1002_02171	COG2920	part of a sulfur-relay system
MIT1002_02178	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MIT1002_02179	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MIT1002_02180	COG1674	ftsk spoiiie
MIT1002_02180	COG0531	amino acid
MIT1002_02183	COG0686	Belongs to the AlaDH PNT family
MIT1002_02184	COG0284	orotidine-5'-phosphate decarboxylase activity
MIT1002_02185	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MIT1002_02188	COG0776	regulation of translation
MIT1002_02189	COG0539	negative regulation of cytoplasmic translation
MIT1002_02190	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MIT1002_02191	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MIT1002_02192	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MIT1002_02194	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MIT1002_02195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIT1002_02196	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIT1002_02197	COG0633	Ferredoxin
MIT1002_02198	COG4221	oxidoreductase activity
MIT1002_02206	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
MIT1002_02207	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIT1002_02209	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MIT1002_02211	COG4783	chaperone-mediated protein folding
MIT1002_02212	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MIT1002_02213	COG1393	Belongs to the ArsC family
MIT1002_02220	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MIT1002_02222	COG1960	acyl-CoA dehydrogenase activity
MIT1002_02227	COG0572	uridine kinase
MIT1002_02228	COG3769	mannosylglycerate metabolic process
MIT1002_02229	COG1215	transferase activity, transferring glycosyl groups
MIT1002_02232	COG0303	'Molybdopterin
MIT1002_02233	COG0534	Mate efflux family protein
MIT1002_02237	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MIT1002_02239	COG3344	reverse transcriptase
MIT1002_02250	COG3011	Protein conserved in bacteria
MIT1002_02259	COG0405	Gamma-glutamyltransferase
MIT1002_02260	COG1024	Enoyl-CoA hydratase
MIT1002_02273	COG1671	Belongs to the UPF0178 family
MIT1002_02274	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_02275	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_02276	COG1960	acyl-CoA dehydrogenase activity
MIT1002_02277	COG0662	Cupin 2, conserved barrel domain protein
MIT1002_02277	COG2207	Transcriptional regulator
MIT1002_02278	COG4771	TonB-dependent receptor
MIT1002_02282	COG1505	serine-type exopeptidase activity
MIT1002_02290	COG0596	Alpha beta hydrolase
MIT1002_02292	COG0716	FMN binding
MIT1002_02294	COG0735	belongs to the Fur family
MIT1002_02296	COG1984	allophanate hydrolase subunit 2
MIT1002_02297	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MIT1002_02298	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MIT1002_02299	COG2996	Protein conserved in bacteria
MIT1002_02300	COG1765	OsmC-like protein
MIT1002_02301	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_02306	COG0436	Aminotransferase
MIT1002_02307	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
MIT1002_02308	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MIT1002_02313	COG3012	SEC-C Motif Domain Protein
MIT1002_02314	COG0366	Alpha amylase catalytic
MIT1002_02315	COG0604	alcohol dehydrogenase
MIT1002_02317	COG1960	acyl-CoA dehydrogenase activity
MIT1002_02319	COG4771	TonB-dependent receptor
MIT1002_02323	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MIT1002_02324	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MIT1002_02328	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MIT1002_02329	COG0315	cyclic pyranopterin monophosphate synthase activity
MIT1002_02330	COG0521	Mo-molybdopterin cofactor biosynthetic process
MIT1002_02331	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MIT1002_02335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MIT1002_02335	COG3321	synthase
MIT1002_02335	COG4221	oxidoreductase activity
MIT1002_02335	COG0604	alcohol dehydrogenase
MIT1002_02336	COG4221	oxidoreductase activity
MIT1002_02337	COG0583	DNA-binding transcription factor activity
MIT1002_02342	COG0826	peptidase U32
MIT1002_02343	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MIT1002_02344	COG0436	Aminotransferase
MIT1002_02345	COG3268	Saccharopine dehydrogenase
MIT1002_02346	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIT1002_02350	COG4771	TonB-dependent receptor
MIT1002_02359	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MIT1002_02360	COG1074	ATP-dependent DNA helicase activity
MIT1002_02361	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MIT1002_02363	COG1022	Amp-dependent synthetase and ligase
MIT1002_02368	COG0583	DNA-binding transcription factor activity
MIT1002_02372	COG0640	Transcriptional regulator
MIT1002_02376	COG2204	response regulator
MIT1002_02378	COG4251	negative regulation of phosphorylation
MIT1002_02379	COG0784	Response regulator, receiver
MIT1002_02380	COG2205	protein histidine kinase activity
MIT1002_02380	COG0784	Response regulator, receiver
MIT1002_02390	COG3139	Protein of unknown function (DUF1315)
MIT1002_02392	COG1115	amino acid carrier protein
MIT1002_02393	COG2866	Carboxypeptidase
MIT1002_02397	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIT1002_02399	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MIT1002_02400	COG1640	4-alpha-glucanotransferase
MIT1002_02402	COG0676	glucose-6-phosphate 1-epimerase activity
MIT1002_02403	COG0800	Aldolase
MIT1002_02405	COG0129	dihydroxy-acid dehydratase activity
MIT1002_02407	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MIT1002_02408	COG1737	Transcriptional regulator
MIT1002_02409	COG0469	pyruvate kinase activity
MIT1002_02414	COG2823	Periplasmic or secreted lipoprotein
MIT1002_02420	COG3665	Urea carboxylase-associated protein
MIT1002_02424	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_02425	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MIT1002_02427	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MIT1002_02430	COG2721	sulfolactate sulfo-lyase activity
MIT1002_02431	COG1904	glucuronate isomerase
MIT1002_02432	COG0246	Mannitol dehydrogenase
MIT1002_02433	COG0800	Aldolase
MIT1002_02434	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIT1002_02436	COG2801	Transposase and inactivated derivatives
MIT1002_02440	COG1968	undecaprenyl-diphosphatase activity
MIT1002_02444	COG2755	lipolytic protein G-D-S-L family
MIT1002_02447	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MIT1002_02449	COG4677	pectinesterase activity
MIT1002_02453	COG2356	endonuclease I
MIT1002_02458	COG0583	DNA-binding transcription factor activity
MIT1002_02460	COG1979	alcohol dehydrogenase
MIT1002_02461	COG1902	pentaerythritol trinitrate reductase activity
MIT1002_02462	COG4251	negative regulation of phosphorylation
MIT1002_02462	COG3706	GGDEF domain
MIT1002_02462	COG2203	Gaf domain
MIT1002_02462	COG5001	Diguanylate cyclase
MIT1002_02464	COG0753	catalase activity
MIT1002_02465	COG0784	Response regulator, receiver
MIT1002_02465	COG3437	response regulator, receiver
MIT1002_02466	COG4191	Histidine kinase
MIT1002_02466	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIT1002_02476	COG0328	RNA-DNA hybrid ribonuclease activity
MIT1002_02488	COG0471	metal ion transport
MIT1002_02491	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIT1002_02491	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIT1002_02492	COG0668	transmembrane transport
MIT1002_02493	COG2226	methyltransferase
MIT1002_02494	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MIT1002_02495	COG0741	lytic transglycosylase activity
MIT1002_02495	COG1388	LysM domain
MIT1002_02499	COG3138	arginine N-succinyltransferase
MIT1002_02500	COG0215	cysteine-tRNA ligase activity
MIT1002_02501	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIT1002_02504	COG2268	Band 7 protein
MIT1002_02505	COG0300	oxidoreductase activity
MIT1002_02508	COG1733	regulation of RNA biosynthetic process
MIT1002_02509	COG0604	alcohol dehydrogenase
MIT1002_02512	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_02513	COG0753	catalase activity
MIT1002_02514	COG1063	alcohol dehydrogenase
MIT1002_02515	COG0583	DNA-binding transcription factor activity
MIT1002_02524	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MIT1002_02525	COG1286	toxin biosynthetic process
MIT1002_02526	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
MIT1002_02527	COG0285	dihydrofolate synthase activity
MIT1002_02532	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIT1002_02536	COG3609	addiction module antidote protein, CC2985 family
MIT1002_02538	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MIT1002_02540	COG0318	PFAM AMP-dependent synthetase and ligase
MIT1002_02542	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIT1002_02542	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MIT1002_02550	COG1119	ATPase activity
MIT1002_02552	COG0523	cobalamin synthesis protein
MIT1002_02553	COG1917	Cupin 2, conserved barrel domain protein
MIT1002_02553	COG4977	sequence-specific DNA binding
MIT1002_02554	COG1335	isochorismatase
MIT1002_02556	COG2031	fatty acid transporter
MIT1002_02557	COG0784	Response regulator, receiver
MIT1002_02557	COG2205	protein histidine kinase activity
MIT1002_02557	COG5002	protein histidine kinase activity
MIT1002_02558	COG0612	Peptidase, M16
MIT1002_02561	COG3101	peptidyl-lysine hydroxylation
MIT1002_02566	COG0446	pyridine nucleotide-disulphide oxidoreductase
MIT1002_02566	COG1902	pentaerythritol trinitrate reductase activity
MIT1002_02571	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MIT1002_02573	COG4399	Belongs to the UPF0754 family
MIT1002_02579	COG2186	Transcriptional regulator
MIT1002_02581	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MIT1002_02582	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIT1002_02583	COG2983	Belongs to the UPF0260 family
MIT1002_02584	COG0179	Fumarylacetoacetate (FAA) hydrolase
MIT1002_02587	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MIT1002_02588	COG0318	PFAM AMP-dependent synthetase and ligase
MIT1002_02589	COG2267	carboxylic ester hydrolase activity
MIT1002_02592	COG1214	PFAM Peptidase M22, glycoprotease
MIT1002_02593	COG1199	ATP-dependent helicase activity
MIT1002_02595	COG2200	EAL domain
MIT1002_02595	COG2199	diguanylate cyclase activity
MIT1002_02604	COG1715	Restriction endonuclease
MIT1002_02620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MIT1002_02632	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MIT1002_02633	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MIT1002_02634	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIT1002_02635	COG0131	Imidazoleglycerol-phosphate dehydratase
MIT1002_02635	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MIT1002_02636	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MIT1002_02641	COG2116	formate transmembrane transporter activity
MIT1002_02642	COG0612	Peptidase, M16
MIT1002_02643	COG0681	Belongs to the peptidase S26 family
MIT1002_02648	COG0326	Molecular chaperone. Has ATPase activity
MIT1002_02649	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MIT1002_02654	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MIT1002_02655	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MIT1002_02658	COG3220	belongs to the UPF0276 family
MIT1002_02668	COG1183	phosphatidylcholine synthase activity
MIT1002_02672	COG0277	FAD linked oxidase domain protein
MIT1002_02673	COG1620	l-lactate permease
MIT1002_02677	COG0542	response to heat
MIT1002_02682	COG1595	DNA-templated transcription, initiation
MIT1002_02685	COG4221	oxidoreductase activity
MIT1002_02688	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MIT1002_02690	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MIT1002_02692	COG0142	geranyltranstransferase activity
MIT1002_02694	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MIT1002_02695	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MIT1002_02697	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MIT1002_02700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIT1002_02700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIT1002_02703	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIT1002_02704	COG0488	(ABC) transporter
MIT1002_02706	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MIT1002_02708	COG0560	Phosphoserine phosphatase
MIT1002_02710	COG0084	hydrolase, TatD family'
MIT1002_02713	COG0571	ribonuclease III activity
MIT1002_02719	COG1595	DNA-templated transcription, initiation
MIT1002_02720	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MIT1002_02723	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MIT1002_02739	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MIT1002_02740	COG1047	Peptidyl-prolyl cis-trans
MIT1002_02742	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MIT1002_02743	COG0196	riboflavin kinase activity
MIT1002_02744	COG0728	peptidoglycan biosynthetic process
MIT1002_02745	COG0268	Binds directly to 16S ribosomal RNA
MIT1002_02749	COG0385	Bile acid
MIT1002_02755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIT1002_02756	COG0776	regulation of translation
MIT1002_02757	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MIT1002_02759	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MIT1002_02760	COG0740	serine-type endopeptidase activity
MIT1002_02761	COG0544	peptidyl-prolyl cis-trans isomerase activity
MIT1002_02772	COG1720	tRNA m6t6A37 methyltransferase activity
MIT1002_02774	COG1234	tRNA 3'-trailer cleavage
MIT1002_02776	COG0123	including yeast histone deacetylase and acetoin utilization protein
MIT1002_02779	COG0516	GMP reductase activity
MIT1002_02779	COG0517	IMP dehydrogenase activity
MIT1002_02780	COG1570	exodeoxyribonuclease VII activity
MIT1002_02785	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MIT1002_02786	COG2976	Protein conserved in bacteria
MIT1002_02790	COG3063	Type IV pilus biogenesis stability protein PilW
MIT1002_02791	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MIT1002_02792	COG3385	transposase activity
MIT1002_02794	COG2166	iron-sulfur cluster assembly
MIT1002_02797	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MIT1002_02798	COG0719	Fe-S assembly protein
MIT1002_02799	COG0396	ATPase activity
MIT1002_02800	COG0719	Fe-S assembly protein
MIT1002_02801	COG1104	cysteine desulfurase activity
MIT1002_02802	COG1959	2 iron, 2 sulfur cluster binding
MIT1002_02804	COG2072	flavoprotein involved in K transport
MIT1002_02805	COG1045	serine acetyltransferase
MIT1002_02806	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MIT1002_02807	COG0483	inositol monophosphate 1-phosphatase activity
MIT1002_02809	COG3279	Response regulator of the LytR AlgR family
MIT1002_02810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIT1002_02811	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIT1002_02812	COG1862	Preprotein translocase
MIT1002_02813	COG0343	queuine tRNA-ribosyltransferase activity
MIT1002_02817	COG1842	Phage shock protein A
MIT1002_02818	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MIT1002_02822	COG0754	glutathionylspermidine amidase activity
MIT1002_02828	COG2066	Belongs to the glutaminase family
MIT1002_02829	COG1785	Belongs to the alkaline phosphatase family
MIT1002_02830	COG0745	RESPONSE REGULATOR receiver
MIT1002_02851	COG0438	transferase activity, transferring glycosyl groups
MIT1002_02854	COG0367	asparagine synthase
MIT1002_02857	COG2327	Polysaccharide pyruvyl transferase
MIT1002_02859	COG2244	polysaccharide biosynthetic process
MIT1002_02868	COG0438	transferase activity, transferring glycosyl groups
MIT1002_02874	COG0489	protein tyrosine kinase activity
MIT1002_02876	COG3267	Type II secretory pathway component ExeA
MIT1002_02876	COG3409	Peptidoglycan-binding domain 1 protein
MIT1002_02877	COG2827	Endonuclease containing a URI domain
MIT1002_02881	COG1560	Kdo2-lipid A biosynthetic process
MIT1002_02885	COG1960	acyl-CoA dehydrogenase activity
MIT1002_02889	COG1435	thymidine kinase activity
MIT1002_02892	COG1609	Transcriptional regulator
MIT1002_02893	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MIT1002_02897	COG1082	Xylose isomerase domain protein TIM barrel
MIT1002_02898	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MIT1002_02899	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIT1002_02902	COG1982	Orn Lys Arg decarboxylase major
MIT1002_02908	COG1012	belongs to the aldehyde dehydrogenase family
MIT1002_02912	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
MIT1002_02913	COG0789	Transcriptional regulator
MIT1002_02919	COG1960	acyl-CoA dehydrogenase activity
MIT1002_02931	COG2080	2 iron, 2 sulfur cluster binding
MIT1002_02932	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MIT1002_02933	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MIT1002_02936	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIT1002_02937	COG4172	Belongs to the ABC transporter superfamily
MIT1002_02938	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_02939	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_02940	COG0693	protein deglycase activity
MIT1002_02941	COG1295	ribonuclease BN
MIT1002_02946	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MIT1002_02960	COG0514	ATP-dependent DNA helicase (RecQ)
MIT1002_02965	COG4251	negative regulation of phosphorylation
MIT1002_02966	COG2133	pyrroloquinoline quinone binding
MIT1002_02971	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MIT1002_02971	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MIT1002_02974	COG0583	DNA-binding transcription factor activity
MIT1002_02976	COG2801	Transposase and inactivated derivatives
MIT1002_02982	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIT1002_02983	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIT1002_02984	COG0006	proline dipeptidase activity
MIT1002_02988	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIT1002_02990	COG2205	protein histidine kinase activity
MIT1002_02991	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MIT1002_02992	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MIT1002_02993	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIT1002_03001	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIT1002_03002	COG0508	dehydrogenase complex catalyzes the overall conversion of
MIT1002_03003	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MIT1002_03007	COG3577	Aspartyl protease
MIT1002_03008	COG0157	Belongs to the NadC ModD family
MIT1002_03009	COG4969	Belongs to the N-Me-Phe pilin family
MIT1002_03010	COG1459	type II secretion system
MIT1002_03011	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MIT1002_03012	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MIT1002_03012	COG0237	dephospho-CoA kinase activity
MIT1002_03013	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
MIT1002_03014	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MIT1002_03015	COG3608	succinylglutamate desuccinylase aspartoacylase
MIT1002_03016	COG0494	nUDIX hydrolase
MIT1002_03018	COG0739	heme binding
MIT1002_03019	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MIT1002_03020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MIT1002_03021	COG0849	cell division
MIT1002_03022	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MIT1002_03023	COG1181	Belongs to the D-alanine--D-alanine ligase family
MIT1002_03026	COG0772	Belongs to the SEDS family
MIT1002_03027	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MIT1002_03029	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MIT1002_03030	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIT1002_03031	COG0768	penicillin binding
MIT1002_03032	COG3116	cell division
MIT1002_03034	COG2001	Belongs to the MraZ family
MIT1002_03038	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIT1002_03039	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_03043	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MIT1002_03043	COG0678	peroxiredoxin activity
MIT1002_03048	COG2204	response regulator
MIT1002_03053	COG0668	transmembrane transport
MIT1002_03054	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MIT1002_03055	COG0189	ligase activity
MIT1002_03056	COG1678	Uncharacterized ACR, COG1678
MIT1002_03057	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MIT1002_03062	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIT1002_03063	COG0762	integral membrane protein
MIT1002_03065	COG1902	pentaerythritol trinitrate reductase activity
MIT1002_03065	COG0446	pyridine nucleotide-disulphide oxidoreductase
MIT1002_03070	COG1764	response to oxidative stress
MIT1002_03071	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIT1002_03073	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MIT1002_03074	COG1396	sequence-specific DNA binding
MIT1002_03075	COG2814	Major facilitator Superfamily
MIT1002_03076	COG0724	RNA recognition motif
MIT1002_03083	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MIT1002_03084	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MIT1002_03085	COG0083	homoserine kinase activity
MIT1002_03088	COG0583	DNA-binding transcription factor activity
MIT1002_03091	COG0640	Transcriptional regulator
MIT1002_03093	COG0431	NADPH-dependent FMN reductase
MIT1002_03094	COG0798	PFAM Bile acid sodium symporter
MIT1002_03095	COG2201	protein-glutamate methylesterase activity
MIT1002_03096	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
MIT1002_03098	COG0642	Histidine kinase
MIT1002_03102	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MIT1002_03109	COG1748	Saccharopine dehydrogenase
MIT1002_03113	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MIT1002_03114	COG3107	peptidoglycan biosynthetic process
MIT1002_03116	COG0438	transferase activity, transferring glycosyl groups
MIT1002_03118	COG2823	Periplasmic or secreted lipoprotein
MIT1002_03122	COG4585	Histidine kinase
MIT1002_03123	COG2197	response regulator
MIT1002_03129	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MIT1002_03130	COG0372	Belongs to the citrate synthase family
MIT1002_03131	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MIT1002_03132	COG2828	Protein conserved in bacteria
MIT1002_03133	COG2199	diguanylate cyclase activity
MIT1002_03133	COG2203	Gaf domain
MIT1002_03137	COG0784	Response regulator, receiver
MIT1002_03137	COG2198	Histidine kinase
MIT1002_03137	COG5002	protein histidine kinase activity
MIT1002_03139	COG0067	glutamate synthase
MIT1002_03139	COG0069	glutamate synthase activity
MIT1002_03139	COG0070	glutamate synthase
MIT1002_03140	COG0493	'glutamate synthase
MIT1002_03143	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIT1002_03144	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MIT1002_03145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MIT1002_03146	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIT1002_03149	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIT1002_03150	COG5507	3-demethylubiquinone-9 3-methyltransferase
MIT1002_03151	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MIT1002_03152	COG1196	nuclear chromosome segregation
MIT1002_03152	COG0741	lytic transglycosylase activity
MIT1002_03152	COG0739	heme binding
MIT1002_03153	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MIT1002_03155	COG0738	Major facilitator superfamily
MIT1002_03157	COG1902	pentaerythritol trinitrate reductase activity
MIT1002_03160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIT1002_03161	COG0625	glutathione transferase activity
MIT1002_03165	COG2894	cell division
MIT1002_03166	COG0850	regulation of cytokinetic process
MIT1002_03173	COG1981	membrane
MIT1002_03176	COG1914	H( )-stimulated, divalent metal cation uptake system
MIT1002_03180	COG0745	RESPONSE REGULATOR receiver
MIT1002_03181	COG1217	gtp-binding protein TYPA
MIT1002_03183	COG0174	glutamine synthetase
MIT1002_03185	COG3852	Histidine kinase
MIT1002_03186	COG2204	response regulator
MIT1002_03187	COG3437	response regulator, receiver
MIT1002_03195	COG0525	valine-tRNA ligase activity
MIT1002_03196	COG2927	DNA polymerase III (CHI subunit)
MIT1002_03197	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MIT1002_03198	COG0795	lipopolysaccharide-transporting ATPase activity
MIT1002_03199	COG0795	lipopolysaccharide-transporting ATPase activity
MIT1002_03210	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MIT1002_03217	COG3341	Caulimovirus viroplasmin
MIT1002_03217	COG0328	RNA-DNA hybrid ribonuclease activity
MIT1002_03221	COG4974	Belongs to the 'phage' integrase family
MIT1002_03226	COG2856	Zn peptidase
MIT1002_03231	COG3436	PFAM IS66 Orf2 family protein
MIT1002_03233	COG3344	reverse transcriptase
MIT1002_03236	COG0701	Predicted permease
MIT1002_03242	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MIT1002_03243	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MIT1002_03244	COG1017	nitric oxide dioxygenase activity
MIT1002_03244	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MIT1002_03245	COG3604	Transcriptional regulator
MIT1002_03250	COG0673	inositol 2-dehydrogenase activity
MIT1002_03251	COG0628	permease
MIT1002_03257	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MIT1002_03259	COG0642	Histidine kinase
MIT1002_03268	COG1971	Probably functions as a manganese efflux pump
MIT1002_03270	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MIT1002_03271	COG1283	sodium-dependent phosphate transmembrane transporter activity
MIT1002_03274	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MIT1002_03275	COG3706	GGDEF domain
MIT1002_03277	COG0679	Auxin Efflux Carrier
MIT1002_03283	COG1131	(ABC) transporter
MIT1002_03285	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MIT1002_03287	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
MIT1002_03292	COG2755	lipolytic protein G-D-S-L family
MIT1002_03297	COG1304	FMN binding
MIT1002_03298	COG4952	isomerase
MIT1002_03299	COG3347	Dehydrogenase
MIT1002_03299	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_03302	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIT1002_03303	COG1414	Transcriptional regulator
MIT1002_03304	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_03305	COG0823	Involved in the tonB-independent uptake of proteins
MIT1002_03307	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MIT1002_03310	COG3254	rhamnose metabolic process
MIT1002_03315	COG4372	Transposase
MIT1002_03318	COG2205	protein histidine kinase activity
MIT1002_03320	COG0348	domain, Protein
MIT1002_03320	COG3901	Regulator of nitric oxide reductase transcription
MIT1002_03322	COG2197	response regulator
MIT1002_03328	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MIT1002_03329	COG0583	DNA-binding transcription factor activity
MIT1002_03330	COG1304	FMN binding
MIT1002_03331	COG0277	FAD linked oxidase domain protein
MIT1002_03333	COG1462	curli production assembly transport component CsgG
MIT1002_03339	COG2197	response regulator
MIT1002_03342	COG0513	Belongs to the DEAD box helicase family
MIT1002_03343	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MIT1002_03343	COG3264	Mechanosensitive ion channel
MIT1002_03352	COG0730	response to heat
MIT1002_03353	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIT1002_03356	COG4191	Histidine kinase
MIT1002_03358	COG0417	DNA replication proofreading
MIT1002_03360	COG0318	PFAM AMP-dependent synthetase and ligase
MIT1002_03373	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIT1002_03375	COG1573	uracil-dna glycosylase
MIT1002_03376	COG3300	MHYT domain
MIT1002_03376	COG5001	Diguanylate cyclase
MIT1002_03380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MIT1002_03384	COG1983	PspC domain protein
MIT1002_03385	COG1842	Phage shock protein A
MIT1002_03387	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIT1002_03388	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MIT1002_03394	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MIT1002_03395	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
MIT1002_03403	COG1484	DNA-dependent DNA replication
MIT1002_03404	COG4584	PFAM Integrase catalytic
MIT1002_03414	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MIT1002_03418	COG3385	transposase activity
MIT1002_03419	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MIT1002_03420	COG0204	Acyl-transferase
MIT1002_03421	COG0204	Acyl-transferase
MIT1002_03422	COG0668	transmembrane transport
MIT1002_03425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MIT1002_03426	COG0733	neurotransmitter:sodium symporter activity
MIT1002_03429	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIT1002_03432	COG0716	FMN binding
MIT1002_03434	COG0848	biopolymer transport protein
MIT1002_03436	COG0457	Tetratricopeptide repeat
MIT1002_03437	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MIT1002_03442	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MIT1002_03443	COG0702	epimerase
MIT1002_03446	COG5002	protein histidine kinase activity
MIT1002_03446	COG5001	Diguanylate cyclase
MIT1002_03448	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MIT1002_03450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MIT1002_03452	COG0583	DNA-binding transcription factor activity
MIT1002_03456	COG4682	membrane
MIT1002_03460	COG1953	Uracil, thiamine, allantoin
MIT1002_03461	COG4771	TonB-dependent receptor
MIT1002_03463	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIT1002_03464	COG0778	Nitroreductase
MIT1002_03465	COG0596	Alpha beta hydrolase
MIT1002_03466	COG0251	oxidation-reduction process
MIT1002_03467	COG1335	isochorismatase
MIT1002_03468	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIT1002_03469	COG1309	transcriptional regulator
MIT1002_03472	COG4628	conserved protein (DUF2132)
MIT1002_03474	COG3265	gluconokinase activity
MIT1002_03475	COG1609	Transcriptional regulator
MIT1002_03476	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MIT1002_03478	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIT1002_03482	COG1477	protein flavinylation
MIT1002_03483	COG2871	sodium ion transport
MIT1002_03484	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MIT1002_03485	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MIT1002_03486	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MIT1002_03487	COG1805	sodium ion transport
MIT1002_03488	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MIT1002_03489	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MIT1002_03490	COG0545	Peptidyl-prolyl cis-trans isomerase
MIT1002_03491	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MIT1002_03492	COG0039	L-malate dehydrogenase activity
MIT1002_03493	COG1438	arginine binding
MIT1002_03498	COG0572	uridine kinase
MIT1002_03499	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MIT1002_03502	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MIT1002_03506	COG0517	IMP dehydrogenase activity
MIT1002_03506	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MIT1002_03507	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIT1002_03511	COG0189	ligase activity
MIT1002_03513	COG0189	ligase activity
MIT1002_03513	COG4067	protein conserved in archaea
MIT1002_03516	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MIT1002_03518	COG1283	sodium-dependent phosphate transmembrane transporter activity
MIT1002_03519	COG0667	Aldo Keto reductase
MIT1002_03538	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MIT1002_03540	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MIT1002_03541	COG0840	transmembrane signaling receptor activity
MIT1002_03553	COG0583	DNA-binding transcription factor activity
MIT1002_03558	COG1091	dTDP-4-dehydrorhamnose reductase activity
MIT1002_03567	COG0438	transferase activity, transferring glycosyl groups
MIT1002_03567	COG1216	Glycosyl transferase, family 2
MIT1002_03577	COG3119	arylsulfatase activity
MIT1002_03580	COG0438	transferase activity, transferring glycosyl groups
MIT1002_03580	COG1216	Glycosyl transferase, family 2
MIT1002_03581	COG0662	Cupin 2, conserved barrel domain protein
MIT1002_03581	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MIT1002_03582	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MIT1002_03585	COG0202	RNA polymerase activity
MIT1002_03591	COG0201	protein transport
MIT1002_03595	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MIT1002_03602	COG0784	Response regulator, receiver
MIT1002_03602	COG5002	protein histidine kinase activity
MIT1002_03605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIT1002_03606	COG0557	exoribonuclease II activity
MIT1002_03610	COG4771	TonB-dependent receptor
MIT1002_03613	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MIT1002_03617	COG2234	aminopeptidase activity
MIT1002_03619	COG4251	negative regulation of phosphorylation
MIT1002_03621	COG1271	oxidase subunit
MIT1002_03622	COG1294	oxidase, subunit
MIT1002_03625	COG1522	sequence-specific DNA binding
MIT1002_03628	COG1278	Cold shock
MIT1002_03629	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MIT1002_03631	COG2226	methyltransferase
MIT1002_03633	COG0339	signal peptide processing
MIT1002_03634	COG2201	protein-glutamate methylesterase activity
MIT1002_03638	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIT1002_03639	COG0243	molybdopterin cofactor binding
MIT1002_03642	COG4946	Tricorn protease homolog
MIT1002_03642	COG1506	peptidase
MIT1002_03642	COG0823	Involved in the tonB-independent uptake of proteins
MIT1002_03652	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_03654	COG2197	response regulator
MIT1002_03660	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MIT1002_03661	COG1278	Cold shock
MIT1002_03664	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MIT1002_03665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIT1002_03668	COG0281	malic enzyme
MIT1002_03670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MIT1002_03676	COG0456	acetyltransferase
MIT1002_03678	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MIT1002_03679	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MIT1002_03680	COG2177	Part of the ABC transporter FtsEX involved in
MIT1002_03681	COG2884	Cell division ATP-binding protein ftsE
MIT1002_03682	COG0552	protein localization to endoplasmic reticulum
MIT1002_03683	COG0742	ribosomal rna small subunit methyltransferase
MIT1002_03685	COG2095	MarC family integral membrane protein
MIT1002_03690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MIT1002_03691	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIT1002_03692	COG0617	tRNA 3'-terminal CCA addition
MIT1002_03693	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MIT1002_03696	COG0076	glutamate decarboxylase activity
MIT1002_03699	COG0842	Transport permease protein
MIT1002_03700	COG1131	(ABC) transporter
MIT1002_03701	COG0745	RESPONSE REGULATOR receiver
MIT1002_03702	COG2205	protein histidine kinase activity
MIT1002_03706	COG1253	flavin adenine dinucleotide binding
MIT1002_03707	COG0701	Predicted permease
MIT1002_03708	COG1966	Carbon starvation protein
MIT1002_03718	COG0848	biopolymer transport protein
MIT1002_03720	COG0811	peptide transport
MIT1002_03724	COG3128	pkhd-type hydroxylase
MIT1002_03729	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MIT1002_03730	COG0049	tRNA binding
MIT1002_03731	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MIT1002_03732	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIT1002_03733	COG0085	RNA polymerase activity
MIT1002_03734	COG0222	ribosome binding
MIT1002_03735	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MIT1002_03736	COG0081	regulation of translation
MIT1002_03737	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MIT1002_03740	COG0250	Participates in transcription elongation, termination and antitermination
MIT1002_03741	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MIT1002_03743	COG1132	(ABC) transporter
MIT1002_03744	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIT1002_03745	COG3590	peptidase
MIT1002_03748	COG0513	Belongs to the DEAD box helicase family
MIT1002_03750	COG0418	dihydroorotase activity
MIT1002_03751	COG3040	lipid binding
MIT1002_03752	COG4989	oxidoreductase activity
MIT1002_03753	COG0346	lactoylglutathione lyase activity
MIT1002_03754	COG0668	transmembrane transport
MIT1002_03758	COG0302	gtp cyclohydrolase
MIT1002_03760	COG2957	Belongs to the agmatine deiminase family
MIT1002_03761	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIT1002_03764	COG1201	RNA secondary structure unwinding
MIT1002_03765	COG2311	Membrane
MIT1002_03768	COG1793	dna ligase
MIT1002_03769	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MIT1002_03770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIT1002_03773	COG0625	glutathione transferase activity
MIT1002_03774	COG0625	glutathione transferase activity
MIT1002_03776	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MIT1002_03779	COG1012	belongs to the aldehyde dehydrogenase family
MIT1002_03780	COG0028	Belongs to the TPP enzyme family
MIT1002_03783	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MIT1002_03784	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MIT1002_03785	COG0330	HflC and HflK could
MIT1002_03786	COG0330	HflC and HflK could
MIT1002_03787	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MIT1002_03788	COG1923	regulation of RNA biosynthetic process
MIT1002_03789	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MIT1002_03792	COG0802	atpase or kinase
MIT1002_03793	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MIT1002_03793	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MIT1002_03794	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MIT1002_03798	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
MIT1002_03799	COG0735	belongs to the Fur family
MIT1002_03803	COG0305	Participates in initiation and elongation during chromosome replication
MIT1002_03808	COG2258	MOSC domain
MIT1002_03822	COG0840	transmembrane signaling receptor activity
MIT1002_03823	COG4191	Histidine kinase
MIT1002_03823	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIT1002_03824	COG0840	transmembrane signaling receptor activity
MIT1002_03827	COG2855	membrane
MIT1002_03828	COG2175	clavaminate synthase activity
MIT1002_03829	COG0656	L-ascorbic acid biosynthetic process
MIT1002_03833	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIT1002_03834	COG4771	TonB-dependent receptor
MIT1002_03838	COG3706	GGDEF domain
MIT1002_03839	COG1757	Na H antiporter
MIT1002_03840	COG1472	Belongs to the glycosyl hydrolase 3 family
MIT1002_03842	COG2723	6-phospho-beta-galactosidase activity
MIT1002_03843	COG1609	Transcriptional regulator
MIT1002_03844	COG2814	Major facilitator Superfamily
MIT1002_03844	COG0477	Major facilitator Superfamily
MIT1002_03845	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MIT1002_03846	COG4988	ABC transporter
MIT1002_03847	COG4890	Cyd operon protein YbgT
MIT1002_03848	COG1294	oxidase, subunit
MIT1002_03856	COG4319	ketosteroid isomerase
MIT1002_03858	COG4771	TonB-dependent receptor
MIT1002_03861	COG1469	GTP cyclohydrolase I activity
MIT1002_03869	COG3237	CsbD-like
MIT1002_03872	COG1595	DNA-templated transcription, initiation
MIT1002_03878	COG0508	dehydrogenase complex catalyzes the overall conversion of
MIT1002_03878	COG0596	Alpha beta hydrolase
MIT1002_03883	COG3038	cytochrome b561
MIT1002_03885	COG1252	NADH dehydrogenase
MIT1002_03886	COG4206	TonB-dependent receptor
MIT1002_03889	COG0583	DNA-binding transcription factor activity
MIT1002_03890	COG2067	long-chain fatty acid transport protein
MIT1002_03891	COG2130	NADP-dependent
MIT1002_03892	COG2203	Gaf domain
MIT1002_03892	COG3706	GGDEF domain
MIT1002_03892	COG4251	negative regulation of phosphorylation
MIT1002_03892	COG5001	Diguanylate cyclase
MIT1002_03893	COG0784	Response regulator, receiver
MIT1002_03893	COG2205	protein histidine kinase activity
MIT1002_03895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIT1002_03896	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MIT1002_03897	COG1349	DNA-binding transcription factor activity
MIT1002_03898	COG0673	inositol 2-dehydrogenase activity
MIT1002_03901	COG0697	spore germination
MIT1002_03902	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIT1002_03903	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MIT1002_03904	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MIT1002_03905	COG1166	arginine decarboxylase activity
MIT1002_03907	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MIT1002_03923	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIT1002_03925	COG0109	protoheme IX farnesyltransferase activity
MIT1002_03929	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MIT1002_03938	COG1324	tolerance protein
MIT1002_03939	COG4232	protein-disulfide reductase activity
MIT1002_03940	COG0739	heme binding
MIT1002_03942	COG0511	ligase activity, forming carbon-carbon bonds
MIT1002_03943	COG0439	Biotin carboxylase
MIT1002_03954	COG0154	amidase activity
MIT1002_03957	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIT1002_03958	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MIT1002_03961	COG0151	Belongs to the GarS family
MIT1002_03964	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MIT1002_03965	COG3954	Phosphoribulokinase
MIT1002_03971	COG1501	Belongs to the glycosyl hydrolase 31 family
MIT1002_03972	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MIT1002_03973	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MIT1002_03975	COG3031	protein transport across the cell outer membrane
MIT1002_03977	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MIT1002_03978	COG1459	type II secretion system
MIT1002_03979	COG2165	general secretion pathway protein
MIT1002_03980	COG2165	general secretion pathway protein
MIT1002_03981	COG2165	general secretion pathway protein
MIT1002_03982	COG4795	General secretion pathway protein
MIT1002_03985	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
MIT1002_03989	COG1012	belongs to the aldehyde dehydrogenase family
MIT1002_03991	COG1011	Hydrolase
MIT1002_03992	COG0494	nUDIX hydrolase
MIT1002_03993	COG1218	3'(2'),5'-bisphosphate nucleotidase
MIT1002_03995	COG2943	transferase activity, transferring hexosyl groups
MIT1002_03996	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
MIT1002_03998	COG3089	Belongs to the UPF0270 family
MIT1002_03999	COG0429	hydrolase of the alpha beta-hydrolase fold
MIT1002_04001	COG0488	(ABC) transporter
MIT1002_04007	COG0545	Peptidyl-prolyl cis-trans isomerase
MIT1002_04011	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MIT1002_04012	COG2183	response to ionizing radiation
MIT1002_04016	COG0596	Alpha beta hydrolase
MIT1002_04017	COG1040	competence protein
MIT1002_04020	COG1794	racemase activity, acting on amino acids and derivatives
MIT1002_04023	COG0534	Mate efflux family protein
MIT1002_04026	COG1999	signal sequence binding
MIT1002_04027	COG0109	protoheme IX farnesyltransferase activity
MIT1002_04028	COG1612	heme a metabolic process
MIT1002_04033	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
MIT1002_04034	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MIT1002_04035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MIT1002_04038	COG3706	GGDEF domain
MIT1002_04041	COG0129	dihydroxy-acid dehydratase activity
MIT1002_04042	COG2860	membrane
MIT1002_04043	COG0606	chelatase, subunit chli
MIT1002_04044	COG0583	DNA-binding transcription factor activity
MIT1002_04046	COG2814	Major facilitator Superfamily
MIT1002_04048	COG0729	surface antigen
MIT1002_04049	COG2911	Protein conserved in bacteria
MIT1002_04054	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIT1002_04056	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIT1002_04060	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MIT1002_04065	COG1228	amidohydrolase
MIT1002_04069	COG0425	Belongs to the sulfur carrier protein TusA family
MIT1002_04072	COG1561	YicC-like family, N-terminal region
MIT1002_04087	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MIT1002_04089	COG0556	nucleotide-excision repair
MIT1002_04096	COG3620	sequence-specific DNA binding
MIT1002_04102	COG2211	Major facilitator Superfamily
MIT1002_04103	COG1609	Transcriptional regulator
MIT1002_04107	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MIT1002_04107	COG2199	diguanylate cyclase activity
MIT1002_04112	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MIT1002_04116	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIT1002_04117	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MIT1002_04121	COG1475	DNA binding
MIT1002_04122	COG1192	Involved in chromosome partitioning
MIT1002_04127	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MIT1002_04128	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MIT1002_04130	COG0706	membrane insertase activity
MIT1002_04131	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MIT1002_04132	COG0594	ribonuclease P activity
MIT1002_04133	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MIT1002_04134	COG1192	Involved in chromosome partitioning
MIT1002_04142	COG3039	Transposase
MIT1002_04151	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MIT1002_04151	COG2010	Cytochrome c
MIT1002_04152	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MIT1002_04155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MIT1002_04166	COG3550	peptidyl-serine autophosphorylation
MIT1002_04167	COG1396	sequence-specific DNA binding
MIT1002_04198	COG3547	Transposase (IS116 IS110 IS902 family)
MIT1002_04199	COG3547	Transposase (IS116 IS110 IS902 family)
MIT1002_04200	COG3209	COG3209 Rhs family protein
MIT1002_04213	COG0784	Response regulator, receiver
MIT1002_04213	COG4191	Histidine kinase
MIT1002_04215	COG2203	Gaf domain
MIT1002_04215	COG5001	Diguanylate cyclase
MIT1002_04215	COG4251	negative regulation of phosphorylation
MIT1002_04215	COG3706	GGDEF domain
MIT1002_04220	COG0840	transmembrane signaling receptor activity
MIT1002_04222	COG2201	protein-glutamate methylesterase activity