locus-tag	class	description
ACZ81_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ACZ81_00020	COG0187	DNA topoisomerase II activity
ACZ81_00040	COG2818	Glycosylase
ACZ81_00050	COG3078	GTPase activator activity
ACZ81_00070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACZ81_00070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACZ81_00075	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ACZ81_00080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACZ81_00085	COG0569	domain protein
ACZ81_00090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACZ81_00090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACZ81_00110	COG0758	DNA mediated transformation
ACZ81_00125	COG0009	L-threonylcarbamoyladenylate synthase
ACZ81_00130	COG0408	coproporphyrinogen oxidase activity
ACZ81_00135	COG3047	cAMP biosynthetic process
ACZ81_00150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACZ81_00225	COG2234	aminopeptidase activity
ACZ81_00235	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACZ81_00260	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACZ81_00290	COG3642	lipopolysaccharide core region biosynthetic process
ACZ81_00320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACZ81_00335	COG3161	chorismate lyase activity
ACZ81_00340	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACZ81_00350	COG0210	DNA helicase
ACZ81_00385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACZ81_00400	COG0556	nucleotide-excision repair
ACZ81_00450	COG0583	DNA-binding transcription factor activity
ACZ81_00460	COG3106	COG3106 Predicted ATPase
ACZ81_00475	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACZ81_00490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACZ81_00495	COG0352	thiamine-phosphate diphosphorylase activity
ACZ81_00505	COG3071	HemY protein
ACZ81_00510	COG2959	enzyme of heme biosynthesis
ACZ81_00520	COG0181	hydroxymethylbilane synthase activity
ACZ81_00525	COG3706	GGDEF domain
ACZ81_00525	COG0745	RESPONSE REGULATOR receiver
ACZ81_00535	COG0194	GDP metabolic process
ACZ81_00545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACZ81_00555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACZ81_00560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACZ81_00570	COG0678	peroxiredoxin activity
ACZ81_00585	COG1178	ABC-type Fe3 transport system permease component
ACZ81_00590	COG3842	ATPase activity
ACZ81_00595	COG2081	HI0933 family
ACZ81_00615	COG1196	nuclear chromosome segregation
ACZ81_00615	COG3264	Mechanosensitive ion channel
ACZ81_00625	COG1595	DNA-templated transcription, initiation
ACZ81_00630	COG0668	transmembrane transport
ACZ81_00640	COG2239	Acts as a magnesium transporter
ACZ81_00650	COG0189	ligase activity
ACZ81_00665	COG3047	cAMP biosynthetic process
ACZ81_00680	COG3706	GGDEF domain
ACZ81_00685	COG0583	DNA-binding transcription factor activity
ACZ81_00695	COG2076	Multidrug Resistance protein
ACZ81_00710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ81_00725	COG0427	acetyl-CoA hydrolase
ACZ81_00730	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACZ81_00745	COG0840	transmembrane signaling receptor activity
ACZ81_00755	COG3064	Membrane
ACZ81_00765	COG5001	Diguanylate cyclase
ACZ81_00765	COG5002	protein histidine kinase activity
ACZ81_00780	COG0514	ATP-dependent DNA helicase (RecQ)
ACZ81_00785	COG2050	protein possibly involved in aromatic compounds catabolism
ACZ81_00790	COG2239	Acts as a magnesium transporter
ACZ81_00795	COG2962	Rard protein
ACZ81_00800	COG3706	GGDEF domain
ACZ81_00805	COG0210	DNA helicase
ACZ81_00820	COG3706	GGDEF domain
ACZ81_00825	COG1011	Hydrolase
ACZ81_00840	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ACZ81_00845	COG0019	diaminopimelate decarboxylase activity
ACZ81_00880	COG0163	prenyltransferase activity
ACZ81_00885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACZ81_00895	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACZ81_00930	COG1077	Cell shape determining protein MreB Mrl
ACZ81_00940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACZ81_00945	COG2814	Major facilitator Superfamily
ACZ81_00950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACZ81_00980	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ACZ81_00990	COG0629	single-stranded DNA binding
ACZ81_01010	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACZ81_01025	COG1349	DNA-binding transcription factor activity
ACZ81_01070	COG3409	Peptidoglycan-binding domain 1 protein
ACZ81_01070	COG3267	Type II secretory pathway component ExeA
ACZ81_01080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACZ81_01085	COG1459	type II secretion system
ACZ81_01130	COG1077	Cell shape determining protein MreB Mrl
ACZ81_01135	COG1792	Involved in formation and maintenance of cell shape
ACZ81_01140	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ACZ81_01150	COG1530	ribonuclease E activity
ACZ81_01160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACZ81_01165	COG0312	modulator of DNA gyrase
ACZ81_01175	COG3028	Belongs to the UPF0307 family
ACZ81_01180	COG0312	modulator of DNA gyrase
ACZ81_01195	COG0745	RESPONSE REGULATOR receiver
ACZ81_01200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ81_01200	COG4191	Histidine kinase
ACZ81_01205	COG0297	glycogen (starch) synthase activity
ACZ81_01215	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACZ81_01325	COG4974	Belongs to the 'phage' integrase family
ACZ81_01340	COG1484	DNA-dependent DNA replication
ACZ81_01345	COG4584	PFAM Integrase catalytic
ACZ81_01420	COG0745	RESPONSE REGULATOR receiver
ACZ81_01430	COG0835	chemotaxis
ACZ81_01445	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ACZ81_01460	COG0745	RESPONSE REGULATOR receiver
ACZ81_01465	COG0643	Histidine kinase
ACZ81_01465	COG2198	Histidine kinase
ACZ81_01470	COG0835	chemotaxis
ACZ81_01490	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ACZ81_01510	COG3385	transposase activity
ACZ81_01550	COG0784	Response regulator, receiver
ACZ81_01550	COG2205	protein histidine kinase activity
ACZ81_01565	COG1609	Transcriptional regulator
ACZ81_01570	COG0673	inositol 2-dehydrogenase activity
ACZ81_01580	COG2211	Major facilitator Superfamily
ACZ81_01605	COG1454	alcohol dehydrogenase
ACZ81_01680	COG0089	rRNA binding
ACZ81_01690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACZ81_01700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACZ81_01715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACZ81_01725	COG1519	Transferase
ACZ81_01770	COG0788	formyltetrahydrofolate deformylase activity
ACZ81_01780	COG1643	Atp-dependent helicase
ACZ81_01790	COG2951	lytic endotransglycosylase activity
ACZ81_01795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACZ81_01805	COG2354	Protein conserved in bacteria
ACZ81_01815	COG4977	sequence-specific DNA binding
ACZ81_01830	COG0004	ammonium transporteR
ACZ81_01835	COG0405	Gamma-glutamyltransferase
ACZ81_01840	COG2837	iron assimilation
ACZ81_01855	COG0540	Belongs to the ATCase OTCase family
ACZ81_01880	COG3850	Histidine kinase
ACZ81_01880	COG3437	response regulator, receiver
ACZ81_01880	COG4999	Histidine kinase
ACZ81_01880	COG2205	protein histidine kinase activity
ACZ81_01895	COG3300	MHYT domain
ACZ81_01895	COG5001	Diguanylate cyclase
ACZ81_01905	COG1012	belongs to the aldehyde dehydrogenase family
ACZ81_01915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACZ81_01925	COG0512	Glutamine amidotransferase of anthranilate synthase
ACZ81_01930	COG0180	Tryptophanyl-tRNA synthetase
ACZ81_01935	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACZ81_01955	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ACZ81_01965	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACZ81_02000	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACZ81_02005	COG0281	malic enzyme
ACZ81_02015	COG0625	glutathione transferase activity
ACZ81_02025	COG0753	catalase activity
ACZ81_02040	COG5001	Diguanylate cyclase
ACZ81_02040	COG3300	MHYT domain
ACZ81_02045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACZ81_02045	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ACZ81_02055	COG0137	argininosuccinate synthase activity
ACZ81_02075	COG1803	Methylglyoxal synthase
ACZ81_02085	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ACZ81_02100	COG0745	RESPONSE REGULATOR receiver
ACZ81_02105	COG2205	protein histidine kinase activity
ACZ81_02110	COG2267	carboxylic ester hydrolase activity
ACZ81_02115	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACZ81_02120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ81_02125	COG0577	efflux transmembrane transporter activity
ACZ81_02125	COG1136	(ABC) transporter
ACZ81_02145	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACZ81_02155	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACZ81_02160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACZ81_02165	COG4942	peptidase
ACZ81_02170	COG2861	carbohydrate metabolic process
ACZ81_02180	COG0584	glycerophosphoryl diester phosphodiesterase
ACZ81_02195	COG1162	GTPase activity
ACZ81_02200	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ACZ81_02220	COG3344	reverse transcriptase
ACZ81_02235	COG0028	Belongs to the TPP enzyme family
ACZ81_02255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACZ81_02260	COG0805	protein transport
ACZ81_02270	COG0084	hydrolase, TatD family'
ACZ81_02275	COG2203	Gaf domain
ACZ81_02275	COG3706	GGDEF domain
ACZ81_02275	COG4251	negative regulation of phosphorylation
ACZ81_02275	COG5001	Diguanylate cyclase
ACZ81_02285	COG0248	Ppx GppA phosphatase
ACZ81_02290	COG0513	Belongs to the DEAD box helicase family
ACZ81_02295	COG3118	belongs to the thioredoxin family
ACZ81_02300	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACZ81_02315	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACZ81_02320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACZ81_02325	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACZ81_02340	COG0783	Belongs to the Dps family
ACZ81_02345	COG2133	pyrroloquinoline quinone binding
ACZ81_02350	COG4946	Tricorn protease homolog
ACZ81_02350	COG0823	Involved in the tonB-independent uptake of proteins
ACZ81_02350	COG1506	peptidase
ACZ81_02360	COG3118	belongs to the thioredoxin family
ACZ81_02375	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ACZ81_02385	COG1012	belongs to the aldehyde dehydrogenase family
ACZ81_02410	COG1757	Na H antiporter
ACZ81_02425	COG3876	Protein conserved in bacteria
ACZ81_02430	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ACZ81_02450	COG0346	lactoylglutathione lyase activity
ACZ81_02485	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACZ81_02495	COG2824	Alkylphosphonate utilization operon protein PhnA
ACZ81_02500	COG0454	-acetyltransferase
ACZ81_02510	COG1742	UPF0060 membrane protein
ACZ81_02565	COG3547	Transposase (IS116 IS110 IS902 family)
ACZ81_02655	COG0183	Belongs to the thiolase family
ACZ81_02660	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACZ81_02660	COG1024	Enoyl-CoA hydratase
ACZ81_02665	COG0739	heme binding
ACZ81_02665	COG0741	lytic transglycosylase activity
ACZ81_02665	COG1196	nuclear chromosome segregation
ACZ81_02670	COG0006	proline dipeptidase activity
ACZ81_02680	COG0142	geranyltranstransferase activity
ACZ81_02730	COG4942	peptidase
ACZ81_02730	COG1388	LysM domain
ACZ81_02735	COG1238	metal cluster binding
ACZ81_02745	COG0585	pseudouridine synthase activity
ACZ81_02750	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACZ81_02760	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACZ81_02770	COG0840	transmembrane signaling receptor activity
ACZ81_02775	COG1522	sequence-specific DNA binding
ACZ81_02790	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACZ81_02790	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACZ81_02790	COG0506	proline dehydrogenase activity
ACZ81_02815	COG0494	nUDIX hydrolase
ACZ81_02820	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ACZ81_02825	COG0730	response to heat
ACZ81_02830	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACZ81_02835	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ACZ81_02845	COG3706	GGDEF domain
ACZ81_02850	COG4999	Histidine kinase
ACZ81_02850	COG3850	Histidine kinase
ACZ81_02850	COG2205	protein histidine kinase activity
ACZ81_02850	COG3437	response regulator, receiver
ACZ81_02855	COG2211	Major facilitator Superfamily
ACZ81_02875	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ACZ81_02890	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACZ81_02895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACZ81_02920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACZ81_02920	COG1648	precorrin-2 dehydrogenase activity
ACZ81_02925	COG0513	Belongs to the DEAD box helicase family
ACZ81_02945	COG1538	Outer membrane efflux protein
ACZ81_02950	COG0494	nUDIX hydrolase
ACZ81_02960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACZ81_02965	COG3150	esterase
ACZ81_02970	COG0187	DNA topoisomerase II activity
ACZ81_02975	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ACZ81_02990	COG0443	Heat shock 70 kDa protein
ACZ81_02995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACZ81_03010	COG5433	transposase activity
ACZ81_03020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACZ81_03040	COG1509	lysine 2,3-aminomutase activity
ACZ81_03070	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACZ81_03090	COG0271	Belongs to the BolA IbaG family
ACZ81_03105	COG3707	response regulator
ACZ81_03115	COG0659	secondary active sulfate transmembrane transporter activity
ACZ81_03120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACZ81_03125	COG2146	nitrite reductase [NAD(P)H] activity
ACZ81_03130	COG0243	molybdopterin cofactor binding
ACZ81_03135	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACZ81_03135	COG1648	precorrin-2 dehydrogenase activity
ACZ81_03140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACZ81_03145	COG0737	Belongs to the 5'-nucleotidase family
ACZ81_03150	COG2203	Gaf domain
ACZ81_03150	COG4251	negative regulation of phosphorylation
ACZ81_03150	COG5001	Diguanylate cyclase
ACZ81_03150	COG3706	GGDEF domain
ACZ81_03160	COG1116	anion transmembrane transporter activity
ACZ81_03160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACZ81_03170	COG1116	anion transmembrane transporter activity
ACZ81_03185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACZ81_03190	COG4206	TonB-dependent receptor
ACZ81_03195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACZ81_03200	COG0348	domain, Protein
ACZ81_03215	COG1960	acyl-CoA dehydrogenase activity
ACZ81_03230	COG4948	Mandelate Racemase Muconate Lactonizing
ACZ81_03245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ81_03250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACZ81_03270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACZ81_03275	COG0358	DNA primase activity
ACZ81_03300	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ACZ81_03305	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACZ81_03320	COG0537	adenosine 5'-monophosphoramidase activity
ACZ81_03335	COG3135	benzoate transporter
ACZ81_03340	COG1396	sequence-specific DNA binding
ACZ81_03345	COG2974	May be involved in recombination
ACZ81_03350	COG4191	Histidine kinase
ACZ81_03350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ81_03355	COG0745	RESPONSE REGULATOR receiver
ACZ81_03360	COG5002	protein histidine kinase activity
ACZ81_03385	COG0811	peptide transport
ACZ81_03390	COG0811	peptide transport
ACZ81_03395	COG0848	biopolymer transport protein
ACZ81_03400	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ACZ81_03410	COG3437	response regulator, receiver
ACZ81_03420	COG0318	PFAM AMP-dependent synthetase and ligase
ACZ81_03430	COG2133	pyrroloquinoline quinone binding
ACZ81_03435	COG1049	propionate catabolic process, 2-methylcitrate cycle
ACZ81_03475	COG0527	aspartate kinase activity
ACZ81_03485	COG0840	transmembrane signaling receptor activity
ACZ81_03490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACZ81_03495	COG2967	ApaG domain
ACZ81_03505	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACZ81_03510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACZ81_03515	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ACZ81_03525	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACZ81_03535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACZ81_03540	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACZ81_03555	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACZ81_03570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACZ81_03575	COG3956	TIGRFAM MazG family protein
ACZ81_03600	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ81_03610	COG0318	PFAM AMP-dependent synthetase and ligase
ACZ81_03620	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACZ81_03650	COG0642	Histidine kinase
ACZ81_03655	COG0745	RESPONSE REGULATOR receiver
ACZ81_03670	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACZ81_03675	COG0723	plastoquinol--plastocyanin reductase activity
ACZ81_03680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ACZ81_03685	COG2857	Cytochrome c1
ACZ81_03690	COG0625	glutathione transferase activity
ACZ81_03695	COG2969	positive regulation of protein catabolic process
ACZ81_03710	COG0745	RESPONSE REGULATOR receiver
ACZ81_03715	COG2239	Acts as a magnesium transporter
ACZ81_03720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACZ81_03730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACZ81_03740	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ACZ81_03745	COG1137	ATPase activity
ACZ81_03750	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACZ81_03760	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACZ81_03775	COG1127	ABC transporter
ACZ81_03780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACZ81_03785	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACZ81_03790	COG2854	intermembrane phospholipid transfer
ACZ81_03800	COG5007	Belongs to the BolA IbaG family
ACZ81_03810	COG3344	reverse transcriptase
ACZ81_03815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACZ81_03820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACZ81_03830	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACZ81_03865	COG2308	Evidence 4 Homologs of previously reported genes of
ACZ81_03870	COG1305	Transglutaminase-like
ACZ81_03890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACZ81_03900	COG4771	TonB-dependent receptor
ACZ81_03905	COG0697	spore germination
ACZ81_03915	COG2205	protein histidine kinase activity
ACZ81_03915	COG0784	Response regulator, receiver
ACZ81_03940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACZ81_03950	COG0126	phosphoglycerate kinase activity
ACZ81_03960	COG3588	fructose-bisphosphate aldolase
ACZ81_03965	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACZ81_03975	COG0745	RESPONSE REGULATOR receiver
ACZ81_03980	COG5002	protein histidine kinase activity
ACZ81_04000	COG1538	Outer membrane efflux protein
ACZ81_04010	COG4946	Tricorn protease homolog
ACZ81_04010	COG1506	peptidase
ACZ81_04010	COG0823	Involved in the tonB-independent uptake of proteins
ACZ81_04015	COG0248	Ppx GppA phosphatase
ACZ81_04020	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ACZ81_04025	COG2716	regulation of RNA biosynthetic process
ACZ81_04030	COG0573	inorganic phosphate transmembrane transporter activity
ACZ81_04040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACZ81_04050	COG0306	phosphate transporter
ACZ81_04060	COG0583	DNA-binding transcription factor activity
ACZ81_04085	COG1272	protein, Hemolysin III
ACZ81_04095	COG1846	Transcriptional regulator
ACZ81_04100	COG1764	response to oxidative stress
ACZ81_04115	COG3547	Transposase (IS116 IS110 IS902 family)
ACZ81_04120	COG1739	Uncharacterized protein family UPF0029
ACZ81_04140	COG0420	3'-5' exonuclease activity
ACZ81_04145	COG0419	ATPase involved in DNA repair
ACZ81_04155	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ACZ81_04180	COG2986	histidine ammonia-lyase
ACZ81_04195	COG2971	BadF BadG BcrA BcrD
ACZ81_04200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACZ81_04210	COG0488	(ABC) transporter
ACZ81_04225	COG0668	transmembrane transport
ACZ81_04240	COG4771	TonB-dependent receptor
ACZ81_04245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ81_04250	COG1129	ABC transporter
ACZ81_04250	COG0842	Transport permease protein
ACZ81_04255	COG0842	Transport permease protein
ACZ81_04260	COG2814	Major facilitator Superfamily
ACZ81_04295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ81_04335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACZ81_04340	COG0745	RESPONSE REGULATOR receiver
ACZ81_04345	COG0642	Histidine kinase
ACZ81_04360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACZ81_04360	COG0425	Belongs to the sulfur carrier protein TusA family
ACZ81_04365	COG0730	response to heat
ACZ81_04420	COG4584	PFAM Integrase catalytic
ACZ81_04425	COG1484	DNA-dependent DNA replication
ACZ81_04505	COG3344	reverse transcriptase
ACZ81_04510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACZ81_04515	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACZ81_04520	COG0513	Belongs to the DEAD box helicase family
ACZ81_04540	COG3409	Peptidoglycan-binding domain 1 protein
ACZ81_04540	COG3267	Type II secretory pathway component ExeA
ACZ81_04565	COG0473	3-isopropylmalate dehydrogenase activity
ACZ81_04570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACZ81_04605	COG4555	ABC transporter
ACZ81_04610	COG1668	transmembrane transport
ACZ81_04630	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACZ81_04635	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACZ81_04640	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACZ81_04650	COG1138	Cytochrome C-type biogenesis protein
ACZ81_04670	COG2853	Lipoprotein
ACZ81_04675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACZ81_04685	COG3104	oligopeptide transport
ACZ81_04715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACZ81_04720	COG3385	transposase activity
ACZ81_04735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACZ81_04740	COG1555	photosystem II stabilization
ACZ81_04740	COG1596	polysaccharide export
ACZ81_04745	COG0473	3-isopropylmalate dehydrogenase activity
ACZ81_04760	COG1611	Belongs to the LOG family
ACZ81_04765	COG3706	GGDEF domain
ACZ81_04765	COG0745	RESPONSE REGULATOR receiver
ACZ81_04810	COG0564	pseudouridine synthase activity
ACZ81_04825	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ACZ81_04830	COG0024	Methionine aminopeptidase
ACZ81_04835	COG0052	Belongs to the universal ribosomal protein uS2 family
ACZ81_04845	COG0528	UMP kinase activity
ACZ81_04855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACZ81_04860	COG0575	Belongs to the CDS family
ACZ81_04870	COG0750	zinc metalloprotease
ACZ81_04885	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACZ81_04905	COG0587	DNA-directed DNA polymerase activity
ACZ81_04910	COG0825	malonyl-CoA metabolic process
ACZ81_04915	COG0037	tRNA processing
ACZ81_04935	COG0590	tRNA wobble adenosine to inosine editing
ACZ81_04945	COG0047	phosphoribosylformylglycinamidine synthase activity
ACZ81_04945	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACZ81_04955	COG2840	Smr protein MutS2
ACZ81_04990	COG0784	Response regulator, receiver
ACZ81_04990	COG0835	chemotaxis
ACZ81_04995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACZ81_05000	COG1815	bacterial-type flagellum-dependent cell motility
ACZ81_05005	COG1558	bacterial-type flagellum-dependent cell motility
ACZ81_05010	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ACZ81_05015	COG1749	Flagellar hook protein flgE
ACZ81_05020	COG4787	bacterial-type flagellum-dependent cell motility
ACZ81_05025	COG4786	Flagellar basal body rod
ACZ81_05040	COG3951	Flagellar rod assembly protein muramidase FlgJ
ACZ81_05040	COG1705	Flagellar rod assembly protein muramidase FlgJ
ACZ81_05045	COG1256	bacterial-type flagellum assembly
ACZ81_05065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACZ81_05100	COG1083	cytidylyl-transferase
ACZ81_05120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACZ81_05125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACZ81_05130	COG2089	acid synthase
ACZ81_05135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACZ81_05140	COG1086	Polysaccharide biosynthesis protein
ACZ81_05150	COG2204	response regulator
ACZ81_05155	COG3852	Histidine kinase
ACZ81_05160	COG2204	response regulator
ACZ81_05165	COG1677	Flagellar hook-basal body complex protein FliE
ACZ81_05175	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACZ81_05225	COG1987	bacterial-type flagellum assembly
ACZ81_05245	COG2989	Protein conserved in bacteria
ACZ81_05250	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACZ81_05260	COG0455	bacterial-type flagellum organization
ACZ81_05275	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ACZ81_05280	COG2198	Histidine kinase
ACZ81_05280	COG0643	Histidine kinase
ACZ81_05290	COG1192	Involved in chromosome partitioning
ACZ81_05300	COG0835	chemotaxis
ACZ81_05315	COG1410	methionine synthase
ACZ81_05315	COG0646	methionine synthase
ACZ81_05320	COG0646	methionine synthase
ACZ81_05320	COG1410	methionine synthase
ACZ81_05330	COG3123	guanosine phosphorylase activity
ACZ81_05340	COG0583	DNA-binding transcription factor activity
ACZ81_05345	COG0583	DNA-binding transcription factor activity
ACZ81_05350	COG0288	reversible hydration of carbon dioxide
ACZ81_05355	COG0659	secondary active sulfate transmembrane transporter activity
ACZ81_05365	COG3344	reverse transcriptase
ACZ81_05375	COG1309	transcriptional regulator
ACZ81_05380	COG3590	peptidase
ACZ81_05390	COG2137	regulation of response to DNA damage stimulus
ACZ81_05395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACZ81_05430	COG5016	pyruvate
ACZ81_05430	COG0511	ligase activity, forming carbon-carbon bonds
ACZ81_05435	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ACZ81_05440	COG4172	Belongs to the ABC transporter superfamily
ACZ81_05450	COG4171	peptide transport system, permease
ACZ81_05455	COG4168	peptide transport system, permease
ACZ81_05460	COG0747	negative chemotaxis
ACZ81_05465	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ACZ81_05470	COG1842	Phage shock protein A
ACZ81_05500	COG0625	glutathione transferase activity
ACZ81_05505	COG1522	sequence-specific DNA binding
ACZ81_05510	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACZ81_05565	COG0811	peptide transport
ACZ81_05570	COG0811	peptide transport
ACZ81_05575	COG0848	biopolymer transport protein
ACZ81_05590	COG1444	tRNA N-acetyltransferase activity
ACZ81_05630	COG0456	acetyltransferase
ACZ81_05645	COG0583	DNA-binding transcription factor activity
ACZ81_05655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACZ81_05660	COG0656	L-ascorbic acid biosynthetic process
ACZ81_05680	COG1846	Transcriptional regulator
ACZ81_05690	COG3275	phosphorelay sensor kinase activity
ACZ81_05695	COG1966	Carbon starvation protein
ACZ81_05715	COG0457	Tetratricopeptide repeat
ACZ81_05730	COG2197	response regulator
ACZ81_05740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACZ81_05770	COG0583	DNA-binding transcription factor activity
ACZ81_05775	COG0702	epimerase
ACZ81_05795	COG1902	pentaerythritol trinitrate reductase activity
ACZ81_05810	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACZ81_05815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACZ81_05820	COG0564	pseudouridine synthase activity
ACZ81_05830	COG0612	Peptidase, M16
ACZ81_05835	COG2918	glutathione biosynthetic process
ACZ81_05860	COG2890	protein-(glutamine-N5) methyltransferase activity
ACZ81_05875	COG2719	SpoVR family
ACZ81_05880	COG2718	Belongs to the UPF0229 family
ACZ81_05885	COG2766	serine protein kinase
ACZ81_05895	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACZ81_05900	COG4771	TonB-dependent receptor
ACZ81_05925	COG0450	alkyl hydroperoxide reductase
ACZ81_05930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACZ81_05935	COG2885	chlorophyll binding
ACZ81_05940	COG0584	glycerophosphoryl diester phosphodiesterase
ACZ81_05945	COG0346	lactoylglutathione lyase activity
ACZ81_05950	COG4221	oxidoreductase activity
ACZ81_05955	COG1278	Cold shock
ACZ81_05970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACZ81_05975	COG4660	Part of a membrane complex involved in electron transport
ACZ81_05980	COG4659	FMN binding
ACZ81_05985	COG4658	electron transport chain
ACZ81_05990	COG4656	Part of a membrane complex involved in electron transport
ACZ81_05995	COG2878	Part of a membrane complex involved in electron transport
ACZ81_06015	COG0534	Mate efflux family protein
ACZ81_06020	COG0556	nucleotide-excision repair
ACZ81_06035	COG0602	queuosine metabolic process
ACZ81_06045	COG3385	transposase activity
ACZ81_06050	COG0367	asparagine synthase
ACZ81_06075	COG3273	potassium ion transport
ACZ81_06075	COG0471	metal ion transport
ACZ81_06090	COG0529	Catalyzes the synthesis of activated sulfate
ACZ81_06095	COG0175	sulfate reduction
ACZ81_06100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACZ81_06105	COG3706	GGDEF domain
ACZ81_06105	COG0745	RESPONSE REGULATOR receiver
ACZ81_06130	COG2304	oxidoreductase activity
ACZ81_06150	COG0714	Associated with various cellular activities
ACZ81_06160	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACZ81_06160	COG1024	Enoyl-CoA hydratase
ACZ81_06170	COG1025	Belongs to the peptidase M16 family
ACZ81_06175	COG2062	phosphohistidine phosphatase, SixA
ACZ81_06185	COG4536	flavin adenine dinucleotide binding
ACZ81_06190	COG4137	Cytochrome C assembly protein
ACZ81_06195	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACZ81_06235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ81_06240	COG1132	(ABC) transporter
ACZ81_06255	COG0228	four-way junction DNA binding
ACZ81_06260	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACZ81_06265	COG0336	Belongs to the RNA methyltransferase TrmD family
ACZ81_06270	COG0335	large ribosomal subunit rRNA binding
ACZ81_06275	COG2860	membrane
ACZ81_06285	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACZ81_06290	COG0287	Prephenate dehydrogenase
ACZ81_06290	COG1605	Chorismate mutase
ACZ81_06320	COG0077	Prephenate dehydratase
ACZ81_06320	COG1605	Chorismate mutase
ACZ81_06325	COG0745	RESPONSE REGULATOR receiver
ACZ81_06330	COG0023	Translation Initiation Factor
ACZ81_06360	COG2205	protein histidine kinase activity
ACZ81_06370	COG2204	response regulator
ACZ81_06385	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACZ81_06390	COG0494	nUDIX hydrolase
ACZ81_06395	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ACZ81_06405	COG2255	four-way junction helicase activity
ACZ81_06410	COG0824	Thioesterase
ACZ81_06415	COG0811	peptide transport
ACZ81_06430	COG0823	Involved in the tonB-independent uptake of proteins
ACZ81_06435	COG2885	chlorophyll binding
ACZ81_06440	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ACZ81_06460	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACZ81_06500	COG4667	esterase of the alpha-beta hydrolase superfamily
ACZ81_06505	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACZ81_06515	COG2205	protein histidine kinase activity
ACZ81_06515	COG0784	Response regulator, receiver
ACZ81_06530	COG3038	cytochrome b561
ACZ81_06550	COG1451	nucleotide metabolic process
ACZ81_06560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACZ81_06570	COG1309	transcriptional regulator
ACZ81_06575	COG4774	siderophore transport
ACZ81_06580	COG3344	reverse transcriptase
ACZ81_06600	COG3706	GGDEF domain
ACZ81_06610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACZ81_06610	COG3008	intermembrane lipid transfer
ACZ81_06615	COG2995	paraquat-inducible protein a
ACZ81_06625	COG0017	Asparaginyl-tRNA synthetase
ACZ81_06640	COG0189	ligase activity
ACZ81_06675	COG2226	methyltransferase
ACZ81_06685	COG3340	Belongs to the peptidase S51 family
ACZ81_06690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACZ81_06695	COG4139	cobalamin transport
ACZ81_06700	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ACZ81_06705	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ACZ81_06710	COG2205	protein histidine kinase activity
ACZ81_06715	COG0745	RESPONSE REGULATOR receiver
ACZ81_06720	COG0569	domain protein
ACZ81_06725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACZ81_06740	COG5265	(ABC) transporter
ACZ81_06750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACZ81_06760	COG0745	RESPONSE REGULATOR receiver
ACZ81_06785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACZ81_06825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACZ81_06840	COG4181	ATPase activity
ACZ81_06845	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ACZ81_06850	COG1090	epimerase
ACZ81_06855	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACZ81_06860	COG0628	permease
ACZ81_06870	COG0745	RESPONSE REGULATOR receiver
ACZ81_06885	COG2350	Protein conserved in bacteria
ACZ81_06900	COG0134	indole-3-glycerol-phosphate synthase activity
ACZ81_06900	COG0135	phosphoribosylanthranilate isomerase activity
ACZ81_06905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACZ81_06915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACZ81_06920	COG0613	PHP domain protein
ACZ81_06925	COG0009	L-threonylcarbamoyladenylate synthase
ACZ81_06935	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACZ81_06945	COG0656	L-ascorbic acid biosynthetic process
ACZ81_06950	COG0110	maltose O-acetyltransferase activity
ACZ81_06965	COG2733	membrane
ACZ81_06970	COG0500	methyltransferase
ACZ81_06975	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACZ81_06980	COG0497	DNA recombination
ACZ81_06985	COG0783	Belongs to the Dps family
ACZ81_07000	COG1454	alcohol dehydrogenase
ACZ81_07005	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ81_07015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACZ81_07020	COG2610	gluconate transmembrane transporter activity
ACZ81_07025	COG4771	TonB-dependent receptor
ACZ81_07035	COG2205	protein histidine kinase activity
ACZ81_07035	COG2198	Histidine kinase
ACZ81_07035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ81_07035	COG0784	Response regulator, receiver
ACZ81_07040	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACZ81_07050	COG0484	heat shock protein binding
ACZ81_07055	COG3909	cytochrome
ACZ81_07065	COG2199	diguanylate cyclase activity
ACZ81_07065	COG2200	EAL domain
ACZ81_07065	COG2202	Pas domain
ACZ81_07080	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACZ81_07090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACZ81_07095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACZ81_07105	COG0840	transmembrane signaling receptor activity
ACZ81_07125	COG0071	Belongs to the small heat shock protein (HSP20) family
ACZ81_07130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACZ81_07135	COG0280	phosphate acetyltransferase
ACZ81_07135	COG0857	belongs to the CobB CobQ family
ACZ81_07140	COG1228	amidohydrolase
ACZ81_07145	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ACZ81_07150	COG4535	Mg2 and Co2 transporter CorC
ACZ81_07160	COG1702	phosphate starvation-inducible protein PhoH
ACZ81_07170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACZ81_07205	COG1607	acyl-coa hydrolase
ACZ81_07210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACZ81_07220	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ81_07230	COG1115	amino acid carrier protein
ACZ81_07275	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACZ81_07280	COG0012	GTP binding
ACZ81_07295	COG1064	alcohol dehydrogenase
ACZ81_07305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACZ81_07315	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACZ81_07320	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ACZ81_07325	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACZ81_07335	COG2890	protein-(glutamine-N5) methyltransferase activity
ACZ81_07340	COG3437	response regulator, receiver
ACZ81_07340	COG0784	Response regulator, receiver
ACZ81_07345	COG3094	Invasion gene expression up-regulator, SirB
ACZ81_07360	COG0583	DNA-binding transcription factor activity
ACZ81_07385	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
ACZ81_07390	COG0515	serine threonine protein kinase
ACZ81_07395	COG2116	formate transmembrane transporter activity
ACZ81_07410	COG0714	Associated with various cellular activities
ACZ81_07420	COG0033	Phosphoglucomutase
ACZ81_07425	COG0058	SHG alpha-glucan phosphorylase activity
ACZ81_07435	COG2988	succinylglutamate desuccinylase activity
ACZ81_07450	COG1301	dicarboxylic acid transport
ACZ81_07470	COG1393	Belongs to the ArsC family
ACZ81_07495	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ACZ81_07515	COG1484	DNA-dependent DNA replication
ACZ81_07520	COG4584	PFAM Integrase catalytic
ACZ81_07590	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ACZ81_07615	COG1322	Protein conserved in bacteria
ACZ81_07625	COG1196	nuclear chromosome segregation
ACZ81_07705	COG5001	Diguanylate cyclase
ACZ81_07705	COG3300	MHYT domain
ACZ81_07720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACZ81_07735	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACZ81_07760	COG1733	regulation of RNA biosynthetic process
ACZ81_07770	COG5001	Diguanylate cyclase
ACZ81_07770	COG3447	MASE1 domain protein
ACZ81_07770	COG5002	protein histidine kinase activity
ACZ81_07780	COG0402	S-adenosylhomocysteine deaminase activity
ACZ81_07785	COG2351	hydroxyisourate hydrolase activity
ACZ81_07800	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACZ81_07810	COG1309	transcriptional regulator
ACZ81_07825	COG2252	PERMEase
ACZ81_07830	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACZ81_07845	COG3706	GGDEF domain
ACZ81_07845	COG0745	RESPONSE REGULATOR receiver
ACZ81_07850	COG2205	protein histidine kinase activity
ACZ81_07850	COG0784	Response regulator, receiver
ACZ81_07865	COG2233	PERMEase
ACZ81_07870	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACZ81_07885	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACZ81_07890	COG0730	response to heat
ACZ81_07900	COG0154	amidase activity
ACZ81_07930	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ81_07950	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACZ81_07970	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACZ81_07980	COG1596	polysaccharide export
ACZ81_07985	COG0489	protein tyrosine kinase activity
ACZ81_07990	COG4464	protein tyrosine phosphatase activity
ACZ81_08025	COG0438	transferase activity, transferring glycosyl groups
ACZ81_08060	COG3385	transposase activity
ACZ81_08070	COG2327	Polysaccharide pyruvyl transferase
ACZ81_08080	COG0438	transferase activity, transferring glycosyl groups
ACZ81_08085	COG1215	transferase activity, transferring glycosyl groups
ACZ81_08105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACZ81_08105	COG0072	phenylalanine-tRNA ligase activity
ACZ81_08140	COG1472	Belongs to the glycosyl hydrolase 3 family
ACZ81_08145	COG2096	Adenosyltransferase
ACZ81_08155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACZ81_08165	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACZ81_08185	COG0708	Exodeoxyribonuclease III
ACZ81_08220	COG2814	Major facilitator Superfamily
ACZ81_08260	COG1024	Enoyl-CoA hydratase
ACZ81_08265	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACZ81_08270	COG1960	acyl-CoA dehydrogenase activity
ACZ81_08275	COG0789	Transcriptional regulator
ACZ81_08280	COG0183	Belongs to the thiolase family
ACZ81_08305	COG2925	Exonuclease
ACZ81_08310	COG5002	protein histidine kinase activity
ACZ81_08310	COG0784	Response regulator, receiver
ACZ81_08310	COG2205	protein histidine kinase activity
ACZ81_08350	COG1643	Atp-dependent helicase
ACZ81_08370	COG3321	synthase
ACZ81_08370	COG0604	alcohol dehydrogenase
ACZ81_08375	COG0328	RNA-DNA hybrid ribonuclease activity
ACZ81_08380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACZ81_08410	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACZ81_08415	COG1136	(ABC) transporter
ACZ81_08420	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACZ81_08425	COG1301	dicarboxylic acid transport
ACZ81_08435	COG3724	N-succinylarginine dihydrolase activity
ACZ81_08440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACZ81_08445	COG3122	Protein conserved in bacteria
ACZ81_08455	COG0583	DNA-binding transcription factor activity
ACZ81_08460	COG0746	molybdenum cofactor guanylyltransferase activity
ACZ81_08465	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACZ81_08470	COG0243	molybdopterin cofactor binding
ACZ81_08480	COG0625	glutathione transferase activity
ACZ81_08495	COG2153	protein acetylation
ACZ81_08510	COG5002	protein histidine kinase activity
ACZ81_08520	COG1530	ribonuclease E activity
ACZ81_08525	COG0564	pseudouridine synthase activity
ACZ81_08530	COG0546	phosphoglycolate phosphatase activity
ACZ81_08535	COG0424	maF-like protein
ACZ81_08540	COG1399	metal-binding, possibly nucleic acid-binding protein
ACZ81_08550	COG0416	fatty acid biosynthetic process
ACZ81_08555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACZ81_08560	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACZ81_08570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACZ81_08575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACZ81_08580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACZ81_08585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACZ81_08600	COG0084	hydrolase, TatD family'
ACZ81_08605	COG0259	pyridoxamine-phosphate oxidase activity
ACZ81_08610	COG0702	epimerase
ACZ81_08615	COG3706	GGDEF domain
ACZ81_08640	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ81_08645	COG0596	Alpha beta hydrolase
ACZ81_08650	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACZ81_08650	COG1024	Enoyl-CoA hydratase
ACZ81_08655	COG0183	Belongs to the thiolase family
ACZ81_08660	COG1960	acyl-CoA dehydrogenase activity
ACZ81_08665	COG0596	Alpha beta hydrolase
ACZ81_08680	COG2390	Transcriptional regulator
ACZ81_08685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACZ81_08695	COG0246	Mannitol dehydrogenase
ACZ81_08715	COG0668	transmembrane transport
ACZ81_08720	COG4771	TonB-dependent receptor
ACZ81_08745	COG2205	protein histidine kinase activity
ACZ81_08745	COG2198	Histidine kinase
ACZ81_08745	COG0784	Response regulator, receiver
ACZ81_08750	COG3437	response regulator, receiver
ACZ81_08760	COG0195	Participates in both transcription termination and antitermination
ACZ81_08775	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACZ81_08790	COG5001	Diguanylate cyclase
ACZ81_08790	COG3300	MHYT domain
ACZ81_08795	COG1187	pseudouridine synthase activity
ACZ81_08805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACZ81_08805	COG3153	acetyltransferase
ACZ81_08840	COG0450	alkyl hydroperoxide reductase
ACZ81_08885	COG1032	radical SAM domain protein
ACZ81_08900	COG4771	TonB-dependent receptor
ACZ81_08905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACZ81_08915	COG4134	Bacterial extracellular solute-binding protein
ACZ81_08925	COG4136	ATPase activity
ACZ81_08930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACZ81_08975	COG0583	DNA-binding transcription factor activity
ACZ81_08980	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACZ81_08990	COG3385	transposase activity
ACZ81_09000	COG0583	DNA-binding transcription factor activity
ACZ81_09020	COG1131	(ABC) transporter
ACZ81_09065	COG1902	pentaerythritol trinitrate reductase activity
ACZ81_09075	COG2867	negative regulation of translational initiation
ACZ81_09080	COG2914	Belongs to the UPF0125 (RnfH) family
ACZ81_09090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACZ81_09095	COG4771	TonB-dependent receptor
ACZ81_09100	COG0457	Tetratricopeptide repeat
ACZ81_09120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACZ81_09120	COG0574	Belongs to the PEP-utilizing enzyme family
ACZ81_09130	COG3344	reverse transcriptase
ACZ81_09160	COG2850	peptidyl-arginine hydroxylation
ACZ81_09170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACZ81_09175	COG2915	High frequency lysogenization protein hflD homolog
ACZ81_09180	COG0482	sulfurtransferase activity
ACZ81_09185	COG1187	pseudouridine synthase activity
ACZ81_09195	COG1278	Cold shock
ACZ81_09200	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACZ81_09205	COG0542	response to heat
ACZ81_09210	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACZ81_09215	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ACZ81_09220	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ACZ81_09225	COG0492	ferredoxin-NADP+ reductase activity
ACZ81_09230	COG3092	negative regulation of chromosome organization
ACZ81_09235	COG3091	SprT-like family
ACZ81_09240	COG0616	signal peptide processing
ACZ81_09255	COG0778	Nitroreductase
ACZ81_09265	COG0252	asparaginase activity
ACZ81_09270	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACZ81_09275	COG0321	lipoyl(octanoyl) transferase activity
ACZ81_09280	COG2921	Belongs to the UPF0250 family
ACZ81_09285	COG1686	Belongs to the peptidase S11 family
ACZ81_09290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACZ81_09295	COG0772	Belongs to the SEDS family
ACZ81_09300	COG0768	penicillin binding
ACZ81_09305	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACZ81_09310	COG0799	negative regulation of ribosome biogenesis
ACZ81_09320	COG1466	dna polymerase III delta subunit
ACZ81_09325	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ACZ81_09330	COG0495	leucyl-tRNA aminoacylation
ACZ81_09340	COG1067	ATP-dependent peptidase activity
ACZ81_09360	COG1534	Rna-binding protein
ACZ81_09365	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ACZ81_09370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACZ81_09375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACZ81_09380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACZ81_09385	COG0149	triose-phosphate isomerase activity
ACZ81_09390	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACZ81_09415	COG1597	lipid kinase activity
ACZ81_09415	COG1803	Methylglyoxal synthase
ACZ81_09425	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ81_09430	COG0561	phosphatase activity
ACZ81_09445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACZ81_09470	COG1185	polyribonucleotide nucleotidyltransferase activity
ACZ81_09485	COG3344	reverse transcriptase
ACZ81_09495	COG3344	reverse transcriptase
ACZ81_09585	COG4584	PFAM Integrase catalytic
ACZ81_09590	COG1484	DNA-dependent DNA replication
ACZ81_09600	COG1484	DNA-dependent DNA replication
ACZ81_09605	COG4584	PFAM Integrase catalytic
ACZ81_09650	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ACZ81_09655	COG1196	nuclear chromosome segregation
ACZ81_09665	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACZ81_09680	COG1132	(ABC) transporter
ACZ81_09685	COG1663	tetraacyldisaccharide 4'-kinase activity
ACZ81_09725	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACZ81_09730	COG0435	Glutathione S-transferase
ACZ81_09760	COG0372	Belongs to the citrate synthase family
ACZ81_09765	COG2009	succinate dehydrogenase
ACZ81_09770	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ACZ81_09775	COG1053	succinate dehydrogenase
ACZ81_09780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACZ81_09785	COG0567	Dehydrogenase, E1 component
ACZ81_09790	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACZ81_09810	COG3344	reverse transcriptase
ACZ81_09835	COG4667	esterase of the alpha-beta hydrolase superfamily
ACZ81_09855	COG0366	Alpha amylase catalytic
ACZ81_09865	COG0366	Alpha amylase catalytic
ACZ81_09865	COG1874	Beta-galactosidase
ACZ81_09870	COG1609	Transcriptional regulator
ACZ81_09880	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ81_09885	COG2267	carboxylic ester hydrolase activity
ACZ81_09890	COG3344	reverse transcriptase
ACZ81_09900	COG0616	signal peptide processing
ACZ81_09915	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACZ81_09920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACZ81_09925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACZ81_09930	COG0386	Belongs to the glutathione peroxidase family
ACZ81_09935	COG2084	Dehydrogenase
ACZ81_09945	COG1960	acyl-CoA dehydrogenase activity
ACZ81_09950	COG1024	Enoyl-CoA hydratase
ACZ81_09955	COG2226	methyltransferase
ACZ81_09960	COG3083	sulfuric ester hydrolase activity
ACZ81_09965	COG3082	Protein of unknown function (DUF1414)
ACZ81_09970	COG3081	Nucleoid-associated protein
ACZ81_09980	COG0739	heme binding
ACZ81_09980	COG0741	lytic transglycosylase activity
ACZ81_09980	COG1196	nuclear chromosome segregation
ACZ81_10000	COG3275	phosphorelay sensor kinase activity
ACZ81_10005	COG3279	Response regulator of the LytR AlgR family
ACZ81_10010	COG0205	6-phosphofructokinase activity
ACZ81_10025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ81_10025	COG2205	protein histidine kinase activity
ACZ81_10070	COG0513	Belongs to the DEAD box helicase family
ACZ81_10075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACZ81_10080	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACZ81_10085	COG0583	DNA-binding transcription factor activity
ACZ81_10105	COG1760	l-serine dehydratase
ACZ81_10125	COG1322	Protein conserved in bacteria
ACZ81_10130	COG1404	Belongs to the peptidase S8 family
ACZ81_10135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACZ81_10140	COG0022	dehydrogenase e1 component
ACZ81_10150	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACZ81_10155	COG0515	serine threonine protein kinase
ACZ81_10160	COG1946	Acyl-CoA thioesterase
ACZ81_10170	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACZ81_10180	COG1956	GAF domain-containing protein
ACZ81_10195	COG0793	Belongs to the peptidase S41A family
ACZ81_10200	COG0733	neurotransmitter:sodium symporter activity
ACZ81_10210	COG0308	aminopeptidase N
ACZ81_10240	COG2902	Dehydrogenase
ACZ81_10245	COG0167	dihydroorotate dehydrogenase activity
ACZ81_10270	COG3130	regulation of translation
ACZ81_10275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACZ81_10290	COG0415	Belongs to the DNA photolyase family
ACZ81_10295	COG0415	Belongs to the DNA photolyase family
ACZ81_10300	COG3046	protein related to deoxyribodipyrimidine photolyase
ACZ81_10310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACZ81_10325	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACZ81_10330	COG0589	response to stress
ACZ81_10340	COG0069	glutamate synthase activity
ACZ81_10355	COG2193	ferroxidase activity
ACZ81_10365	COG3278	Belongs to the heme-copper respiratory oxidase family
ACZ81_10380	COG2010	Cytochrome c
ACZ81_10405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACZ81_10410	COG0589	response to stress
ACZ81_10420	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACZ81_10440	COG1280	lysine exporter protein (LysE YggA)
ACZ81_10445	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACZ81_10450	COG2897	thiosulfate sulfurtransferase activity
ACZ81_10455	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ACZ81_10485	COG0322	excinuclease ABC activity
ACZ81_10490	COG2197	response regulator
ACZ81_10495	COG1741	Belongs to the pirin family
ACZ81_10525	COG3384	dioxygenase
ACZ81_10530	COG2259	Doxx family
ACZ81_10535	COG0583	DNA-binding transcription factor activity
ACZ81_10550	COG0670	Belongs to the BI1 family
ACZ81_10555	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ACZ81_10570	COG2920	part of a sulfur-relay system
ACZ81_10600	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACZ81_10605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACZ81_10610	COG1674	ftsk spoiiie
ACZ81_10610	COG0531	amino acid
ACZ81_10620	COG0686	Belongs to the AlaDH PNT family
ACZ81_10630	COG0284	orotidine-5'-phosphate decarboxylase activity
ACZ81_10635	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ACZ81_10650	COG3344	reverse transcriptase
ACZ81_10655	COG0776	regulation of translation
ACZ81_10660	COG0539	negative regulation of cytoplasmic translation
ACZ81_10665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACZ81_10670	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACZ81_10675	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ACZ81_10685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACZ81_10690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACZ81_10695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACZ81_10700	COG0633	Ferredoxin
ACZ81_10705	COG4221	oxidoreductase activity
ACZ81_10730	COG3706	GGDEF domain
ACZ81_10730	COG0745	RESPONSE REGULATOR receiver
ACZ81_10745	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ACZ81_10750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACZ81_10760	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACZ81_10770	COG4783	chaperone-mediated protein folding
ACZ81_10775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACZ81_10780	COG1393	Belongs to the ArsC family
ACZ81_10815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACZ81_10825	COG1960	acyl-CoA dehydrogenase activity
ACZ81_10850	COG0572	uridine kinase
ACZ81_10855	COG3769	mannosylglycerate metabolic process
ACZ81_10860	COG1215	transferase activity, transferring glycosyl groups
ACZ81_10875	COG0303	'Molybdopterin
ACZ81_10880	COG0534	Mate efflux family protein
ACZ81_10900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACZ81_10925	COG3547	Transposase (IS116 IS110 IS902 family)
ACZ81_10960	COG3011	Protein conserved in bacteria
ACZ81_11005	COG0405	Gamma-glutamyltransferase
ACZ81_11010	COG1024	Enoyl-CoA hydratase
ACZ81_11075	COG1671	Belongs to the UPF0178 family
ACZ81_11080	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ81_11085	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ81_11090	COG1960	acyl-CoA dehydrogenase activity
ACZ81_11095	COG2207	Transcriptional regulator
ACZ81_11095	COG0662	Cupin 2, conserved barrel domain protein
ACZ81_11110	COG1505	serine-type exopeptidase activity
ACZ81_11150	COG0596	Alpha beta hydrolase
ACZ81_11160	COG0716	FMN binding
ACZ81_11170	COG0735	belongs to the Fur family
ACZ81_11180	COG1984	allophanate hydrolase subunit 2
ACZ81_11185	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ACZ81_11190	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ACZ81_11195	COG2996	Protein conserved in bacteria
ACZ81_11200	COG1765	OsmC-like protein
ACZ81_11205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ81_11230	COG0436	Aminotransferase
ACZ81_11235	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ACZ81_11240	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ACZ81_11265	COG3012	SEC-C Motif Domain Protein
ACZ81_11270	COG0366	Alpha amylase catalytic
ACZ81_11275	COG0604	alcohol dehydrogenase
ACZ81_11285	COG1960	acyl-CoA dehydrogenase activity
ACZ81_11295	COG4771	TonB-dependent receptor
ACZ81_11315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACZ81_11320	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACZ81_11340	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ACZ81_11345	COG0315	cyclic pyranopterin monophosphate synthase activity
ACZ81_11350	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACZ81_11355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACZ81_11365	COG2423	ornithine cyclodeaminase activity
ACZ81_11370	COG0436	Aminotransferase
ACZ81_11375	COG1522	sequence-specific DNA binding
ACZ81_11395	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACZ81_11405	COG3268	Saccharopine dehydrogenase
ACZ81_11410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACZ81_11425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACZ81_11430	COG4771	TonB-dependent receptor
ACZ81_11440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACZ81_11445	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACZ81_11445	COG2146	nitrite reductase [NAD(P)H] activity
ACZ81_11455	COG3547	Transposase (IS116 IS110 IS902 family)
ACZ81_11485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACZ81_11500	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACZ81_11505	COG1074	ATP-dependent DNA helicase activity
ACZ81_11510	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACZ81_11520	COG1022	Amp-dependent synthetase and ligase
ACZ81_11550	COG0583	DNA-binding transcription factor activity
ACZ81_11565	COG0640	Transcriptional regulator
ACZ81_11585	COG2204	response regulator
ACZ81_11595	COG4251	negative regulation of phosphorylation
ACZ81_11600	COG0784	Response regulator, receiver
ACZ81_11605	COG2205	protein histidine kinase activity
ACZ81_11605	COG0784	Response regulator, receiver
ACZ81_11660	COG3139	Protein of unknown function (DUF1315)
ACZ81_11670	COG1115	amino acid carrier protein
ACZ81_11675	COG2866	Carboxypeptidase
ACZ81_11695	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ACZ81_11705	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACZ81_11710	COG1640	4-alpha-glucanotransferase
ACZ81_11720	COG0676	glucose-6-phosphate 1-epimerase activity
ACZ81_11725	COG0800	Aldolase
ACZ81_11735	COG0129	dihydroxy-acid dehydratase activity
ACZ81_11745	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACZ81_11750	COG1737	Transcriptional regulator
ACZ81_11755	COG0469	pyruvate kinase activity
ACZ81_11760	COG4584	PFAM Integrase catalytic
ACZ81_11765	COG1484	DNA-dependent DNA replication
ACZ81_11770	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACZ81_11790	COG2823	Periplasmic or secreted lipoprotein
ACZ81_11815	COG3665	Urea carboxylase-associated protein
ACZ81_11835	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ81_11840	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ACZ81_11850	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ACZ81_11865	COG2721	sulfolactate sulfo-lyase activity
ACZ81_11870	COG1904	glucuronate isomerase
ACZ81_11875	COG0246	Mannitol dehydrogenase
ACZ81_11880	COG0800	Aldolase
ACZ81_11885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACZ81_11890	COG2755	lipolytic protein G-D-S-L family
ACZ81_11900	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ACZ81_11930	COG2356	endonuclease I
ACZ81_11955	COG0583	DNA-binding transcription factor activity
ACZ81_11965	COG1979	alcohol dehydrogenase
ACZ81_11970	COG1902	pentaerythritol trinitrate reductase activity
ACZ81_11975	COG2203	Gaf domain
ACZ81_11975	COG3706	GGDEF domain
ACZ81_11975	COG4251	negative regulation of phosphorylation
ACZ81_11975	COG5001	Diguanylate cyclase
ACZ81_11985	COG0753	catalase activity
ACZ81_11990	COG0784	Response regulator, receiver
ACZ81_11990	COG3437	response regulator, receiver
ACZ81_11995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ81_11995	COG4191	Histidine kinase
ACZ81_12070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACZ81_12100	COG0471	metal ion transport
ACZ81_12110	COG0489	protein tyrosine kinase activity
ACZ81_12115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACZ81_12115	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACZ81_12120	COG0668	transmembrane transport
ACZ81_12125	COG2226	methyltransferase
ACZ81_12130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACZ81_12135	COG1388	LysM domain
ACZ81_12135	COG0741	lytic transglycosylase activity
ACZ81_12160	COG0215	cysteine-tRNA ligase activity
ACZ81_12165	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACZ81_12170	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACZ81_12180	COG2268	Band 7 protein
ACZ81_12185	COG0583	DNA-binding transcription factor activity
ACZ81_12190	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ81_12200	COG1733	regulation of RNA biosynthetic process
ACZ81_12205	COG0604	alcohol dehydrogenase
ACZ81_12210	COG0861	Integral membrane protein TerC family
ACZ81_12215	COG1063	alcohol dehydrogenase
ACZ81_12220	COG0583	DNA-binding transcription factor activity
ACZ81_12255	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACZ81_12260	COG1286	toxin biosynthetic process
ACZ81_12265	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ACZ81_12270	COG0285	dihydrofolate synthase activity
ACZ81_12300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACZ81_12320	COG3609	addiction module antidote protein, CC2985 family
ACZ81_12325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACZ81_12330	COG0318	PFAM AMP-dependent synthetase and ligase
ACZ81_12340	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ACZ81_12340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACZ81_12380	COG0789	Transcriptional regulator
ACZ81_12390	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ81_12395	COG1119	ATPase activity
ACZ81_12405	COG0523	cobalamin synthesis protein
ACZ81_12410	COG4977	sequence-specific DNA binding
ACZ81_12410	COG1917	Cupin 2, conserved barrel domain protein
ACZ81_12415	COG1335	isochorismatase
ACZ81_12425	COG2031	fatty acid transporter
ACZ81_12430	COG2205	protein histidine kinase activity
ACZ81_12430	COG0784	Response regulator, receiver
ACZ81_12430	COG5002	protein histidine kinase activity
ACZ81_12435	COG0612	Peptidase, M16
ACZ81_12450	COG3101	peptidyl-lysine hydroxylation
ACZ81_12475	COG1902	pentaerythritol trinitrate reductase activity
ACZ81_12475	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACZ81_12500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACZ81_12510	COG4399	Belongs to the UPF0754 family
ACZ81_12540	COG2186	Transcriptional regulator
ACZ81_12550	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ACZ81_12555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACZ81_12560	COG2983	Belongs to the UPF0260 family
ACZ81_12565	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACZ81_12580	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ACZ81_12585	COG0318	PFAM AMP-dependent synthetase and ligase
ACZ81_12590	COG2267	carboxylic ester hydrolase activity
ACZ81_12605	COG1214	PFAM Peptidase M22, glycoprotease
ACZ81_12610	COG1199	ATP-dependent helicase activity
ACZ81_12695	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACZ81_12700	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACZ81_12705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACZ81_12710	COG0131	Imidazoleglycerol-phosphate dehydratase
ACZ81_12710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACZ81_12715	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACZ81_12730	COG0140	phosphoribosyl-ATP diphosphatase activity
ACZ81_12730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACZ81_12745	COG2116	formate transmembrane transporter activity
ACZ81_12750	COG0612	Peptidase, M16
ACZ81_12775	COG0326	Molecular chaperone. Has ATPase activity
ACZ81_12780	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACZ81_12805	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACZ81_12810	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACZ81_12820	COG3220	belongs to the UPF0276 family
ACZ81_12865	COG1183	phosphatidylcholine synthase activity
ACZ81_12885	COG0277	FAD linked oxidase domain protein
ACZ81_12890	COG1620	l-lactate permease
ACZ81_12910	COG0542	response to heat
ACZ81_12920	COG0564	pseudouridine synthase activity
ACZ81_12935	COG1595	DNA-templated transcription, initiation
ACZ81_12950	COG4221	oxidoreductase activity
ACZ81_12965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACZ81_12975	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACZ81_12985	COG0142	geranyltranstransferase activity
ACZ81_12995	COG3344	reverse transcriptase
ACZ81_13000	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACZ81_13005	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACZ81_13015	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACZ81_13030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACZ81_13030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACZ81_13050	COG0488	(ABC) transporter
ACZ81_13060	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACZ81_13070	COG0560	Phosphoserine phosphatase
ACZ81_13080	COG0084	hydrolase, TatD family'
ACZ81_13095	COG0571	ribonuclease III activity
ACZ81_13100	COG0681	Belongs to the peptidase S26 family
ACZ81_13125	COG1595	DNA-templated transcription, initiation
ACZ81_13130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ACZ81_13145	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ACZ81_13230	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACZ81_13235	COG1047	Peptidyl-prolyl cis-trans
ACZ81_13245	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACZ81_13250	COG0196	riboflavin kinase activity
ACZ81_13255	COG0728	peptidoglycan biosynthetic process
ACZ81_13260	COG0268	Binds directly to 16S ribosomal RNA
ACZ81_13275	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ81_13280	COG0385	Bile acid
ACZ81_13305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACZ81_13310	COG0776	regulation of translation
ACZ81_13315	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACZ81_13320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACZ81_13325	COG0740	serine-type endopeptidase activity
ACZ81_13330	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACZ81_13385	COG1720	tRNA m6t6A37 methyltransferase activity
ACZ81_13395	COG1234	tRNA 3'-trailer cleavage
ACZ81_13405	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACZ81_13420	COG0516	GMP reductase activity
ACZ81_13420	COG0517	IMP dehydrogenase activity
ACZ81_13425	COG1570	exodeoxyribonuclease VII activity
ACZ81_13450	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACZ81_13455	COG2976	Protein conserved in bacteria
ACZ81_13475	COG3063	Type IV pilus biogenesis stability protein PilW
ACZ81_13480	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACZ81_13490	COG2166	iron-sulfur cluster assembly
ACZ81_13505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACZ81_13510	COG0719	Fe-S assembly protein
ACZ81_13515	COG0396	ATPase activity
ACZ81_13520	COG0719	Fe-S assembly protein
ACZ81_13525	COG1104	cysteine desulfurase activity
ACZ81_13530	COG1959	2 iron, 2 sulfur cluster binding
ACZ81_13540	COG2072	flavoprotein involved in K transport
ACZ81_13545	COG1045	serine acetyltransferase
ACZ81_13550	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ACZ81_13555	COG0483	inositol monophosphate 1-phosphatase activity
ACZ81_13565	COG3279	Response regulator of the LytR AlgR family
ACZ81_13570	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACZ81_13575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACZ81_13580	COG1862	Preprotein translocase
ACZ81_13585	COG0343	queuine tRNA-ribosyltransferase activity
ACZ81_13605	COG1842	Phage shock protein A
ACZ81_13630	COG0754	glutathionylspermidine amidase activity
ACZ81_13660	COG2066	Belongs to the glutaminase family
ACZ81_13665	COG1785	Belongs to the alkaline phosphatase family
ACZ81_13720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACZ81_13750	COG2171	N-acyltransferase activity
ACZ81_13770	COG0438	transferase activity, transferring glycosyl groups
ACZ81_13790	COG0367	asparagine synthase
ACZ81_13880	COG0489	protein tyrosine kinase activity
ACZ81_13890	COG3409	Peptidoglycan-binding domain 1 protein
ACZ81_13890	COG3267	Type II secretory pathway component ExeA
ACZ81_13895	COG2827	Endonuclease containing a URI domain
ACZ81_13915	COG1560	Kdo2-lipid A biosynthetic process
ACZ81_13930	COG1960	acyl-CoA dehydrogenase activity
ACZ81_13950	COG1435	thymidine kinase activity
ACZ81_13965	COG1609	Transcriptional regulator
ACZ81_13970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ACZ81_13990	COG1082	Xylose isomerase domain protein TIM barrel
ACZ81_14000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACZ81_14045	COG1012	belongs to the aldehyde dehydrogenase family
ACZ81_14065	COG3706	GGDEF domain
ACZ81_14070	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ACZ81_14075	COG0789	Transcriptional regulator
ACZ81_14105	COG1960	acyl-CoA dehydrogenase activity
ACZ81_14165	COG2080	2 iron, 2 sulfur cluster binding
ACZ81_14170	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACZ81_14175	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACZ81_14225	COG0601	transmembrane transport
ACZ81_14235	COG4172	Belongs to the ABC transporter superfamily
ACZ81_14240	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ81_14250	COG0693	protein deglycase activity
ACZ81_14255	COG1295	ribonuclease BN
ACZ81_14310	COG4681	YaeQ
ACZ81_14355	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACZ81_14385	COG0514	ATP-dependent DNA helicase (RecQ)
ACZ81_14410	COG4251	negative regulation of phosphorylation
ACZ81_14415	COG2133	pyrroloquinoline quinone binding
ACZ81_14470	COG0738	Major facilitator superfamily
ACZ81_14475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACZ81_14485	COG2971	BadF BadG BcrA BcrD
ACZ81_14510	COG0583	DNA-binding transcription factor activity
ACZ81_14535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACZ81_14540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACZ81_14545	COG0006	proline dipeptidase activity
ACZ81_14560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACZ81_14570	COG2205	protein histidine kinase activity
ACZ81_14580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACZ81_14585	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ACZ81_14590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACZ81_14615	COG3313	Fe-S protein
ACZ81_14640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACZ81_14645	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACZ81_14650	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ACZ81_14655	COG2186	Transcriptional regulator
ACZ81_14670	COG3577	Aspartyl protease
ACZ81_14675	COG0157	Belongs to the NadC ModD family
ACZ81_14680	COG4969	Belongs to the N-Me-Phe pilin family
ACZ81_14685	COG1459	type II secretion system
ACZ81_14690	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ACZ81_14695	COG0237	dephospho-CoA kinase activity
ACZ81_14695	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ACZ81_14700	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ACZ81_14710	COG3608	succinylglutamate desuccinylase aspartoacylase
ACZ81_14715	COG0494	nUDIX hydrolase
ACZ81_14725	COG0739	heme binding
ACZ81_14730	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ACZ81_14735	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACZ81_14740	COG0849	cell division
ACZ81_14745	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACZ81_14750	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACZ81_14765	COG0772	Belongs to the SEDS family
ACZ81_14770	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACZ81_14780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACZ81_14785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACZ81_14790	COG0768	penicillin binding
ACZ81_14795	COG3116	cell division
ACZ81_14805	COG2001	Belongs to the MraZ family
ACZ81_14825	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACZ81_14830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ81_14850	COG0678	peroxiredoxin activity
ACZ81_14850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACZ81_14865	COG3706	GGDEF domain
ACZ81_14875	COG2204	response regulator
ACZ81_14900	COG0668	transmembrane transport
ACZ81_14905	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACZ81_14910	COG0189	ligase activity
ACZ81_14915	COG1678	Uncharacterized ACR, COG1678
ACZ81_14920	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACZ81_14945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACZ81_14950	COG0762	integral membrane protein
ACZ81_14960	COG1902	pentaerythritol trinitrate reductase activity
ACZ81_14960	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACZ81_14985	COG1764	response to oxidative stress
ACZ81_14990	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACZ81_14990	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACZ81_15000	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACZ81_15015	COG2814	Major facilitator Superfamily
ACZ81_15020	COG0724	RNA recognition motif
ACZ81_15045	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACZ81_15055	COG0083	homoserine kinase activity
ACZ81_15065	COG0583	DNA-binding transcription factor activity
ACZ81_15075	COG2197	response regulator
ACZ81_15080	COG4585	Histidine kinase
ACZ81_15095	COG0640	Transcriptional regulator
ACZ81_15105	COG0431	NADPH-dependent FMN reductase
ACZ81_15110	COG0798	PFAM Bile acid sodium symporter
ACZ81_15115	COG2201	protein-glutamate methylesterase activity
ACZ81_15120	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ACZ81_15130	COG0642	Histidine kinase
ACZ81_15150	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ACZ81_15160	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACZ81_15180	COG3547	Transposase (IS116 IS110 IS902 family)
ACZ81_15190	COG1748	Saccharopine dehydrogenase
ACZ81_15210	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ACZ81_15215	COG3107	peptidoglycan biosynthetic process
ACZ81_15235	COG2823	Periplasmic or secreted lipoprotein
ACZ81_15250	COG2076	Multidrug Resistance protein
ACZ81_15255	COG4585	Histidine kinase
ACZ81_15260	COG2197	response regulator
ACZ81_15285	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ACZ81_15290	COG0372	Belongs to the citrate synthase family
ACZ81_15295	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACZ81_15300	COG2828	Protein conserved in bacteria
ACZ81_15305	COG2199	diguanylate cyclase activity
ACZ81_15305	COG2203	Gaf domain
ACZ81_15325	COG5002	protein histidine kinase activity
ACZ81_15325	COG0784	Response regulator, receiver
ACZ81_15325	COG2198	Histidine kinase
ACZ81_15335	COG0070	glutamate synthase
ACZ81_15335	COG0069	glutamate synthase activity
ACZ81_15335	COG0067	glutamate synthase
ACZ81_15340	COG0493	'glutamate synthase
ACZ81_15360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACZ81_15365	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ACZ81_15370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACZ81_15390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACZ81_15395	COG5507	3-demethylubiquinone-9 3-methyltransferase
ACZ81_15405	COG0739	heme binding
ACZ81_15405	COG0741	lytic transglycosylase activity
ACZ81_15405	COG1196	nuclear chromosome segregation
ACZ81_15410	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ACZ81_15420	COG0738	Major facilitator superfamily
ACZ81_15430	COG1902	pentaerythritol trinitrate reductase activity
ACZ81_15445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACZ81_15450	COG0625	glutathione transferase activity
ACZ81_15470	COG2894	cell division
ACZ81_15475	COG0850	regulation of cytokinetic process
ACZ81_15525	COG1914	H( )-stimulated, divalent metal cation uptake system
ACZ81_15545	COG0174	glutamine synthetase
ACZ81_15555	COG3852	Histidine kinase
ACZ81_15560	COG2204	response regulator
ACZ81_15565	COG3437	response regulator, receiver
ACZ81_15570	COG0204	Acyl-transferase
ACZ81_15610	COG0525	valine-tRNA ligase activity
ACZ81_15615	COG2927	DNA polymerase III (CHI subunit)
ACZ81_15620	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACZ81_15625	COG0795	lipopolysaccharide-transporting ATPase activity
ACZ81_15630	COG0795	lipopolysaccharide-transporting ATPase activity
ACZ81_15700	COG0701	Predicted permease
ACZ81_15745	COG0673	inositol 2-dehydrogenase activity
ACZ81_15750	COG0784	Response regulator, receiver
ACZ81_15750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ81_15750	COG2205	protein histidine kinase activity
ACZ81_15750	COG2198	Histidine kinase
ACZ81_15755	COG0628	permease
ACZ81_15790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACZ81_15800	COG0642	Histidine kinase
ACZ81_15830	COG0697	spore germination
ACZ81_15850	COG1971	Probably functions as a manganese efflux pump
ACZ81_15870	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACZ81_15875	COG3706	GGDEF domain
ACZ81_15880	COG0679	Auxin Efflux Carrier
ACZ81_15910	COG1131	(ABC) transporter
ACZ81_15930	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
ACZ81_15970	COG2205	protein histidine kinase activity
ACZ81_15980	COG3901	Regulator of nitric oxide reductase transcription
ACZ81_15980	COG0348	domain, Protein
ACZ81_15990	COG2197	response regulator
ACZ81_16020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACZ81_16035	COG4771	TonB-dependent receptor
ACZ81_16045	COG0583	DNA-binding transcription factor activity
ACZ81_16050	COG1304	FMN binding
ACZ81_16055	COG0277	FAD linked oxidase domain protein
ACZ81_16065	COG1462	curli production assembly transport component CsgG
ACZ81_16095	COG2197	response regulator
ACZ81_16110	COG0513	Belongs to the DEAD box helicase family
ACZ81_16115	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ACZ81_16115	COG3264	Mechanosensitive ion channel
ACZ81_16155	COG0730	response to heat
ACZ81_16175	COG4191	Histidine kinase
ACZ81_16185	COG0417	DNA replication proofreading
ACZ81_16195	COG0318	PFAM AMP-dependent synthetase and ligase
ACZ81_16250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACZ81_16260	COG1573	uracil-dna glycosylase
ACZ81_16265	COG3300	MHYT domain
ACZ81_16265	COG5001	Diguanylate cyclase
ACZ81_16285	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACZ81_16305	COG1983	PspC domain protein
ACZ81_16310	COG1842	Phage shock protein A
ACZ81_16320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACZ81_16345	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ACZ81_16350	COG0204	Acyl-transferase
ACZ81_16355	COG0204	Acyl-transferase
ACZ81_16360	COG0668	transmembrane transport
ACZ81_16375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACZ81_16380	COG0733	neurotransmitter:sodium symporter activity
ACZ81_16395	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACZ81_16410	COG0716	FMN binding
ACZ81_16420	COG0848	biopolymer transport protein
ACZ81_16430	COG0457	Tetratricopeptide repeat
ACZ81_16435	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ACZ81_16460	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ACZ81_16465	COG0702	epimerase
ACZ81_16480	COG5001	Diguanylate cyclase
ACZ81_16480	COG5002	protein histidine kinase activity
ACZ81_16490	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ACZ81_16500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACZ81_16510	COG0583	DNA-binding transcription factor activity
ACZ81_16520	COG0121	glutamine amidotransferase
ACZ81_16540	COG4682	membrane
ACZ81_16565	COG1953	Uracil, thiamine, allantoin
ACZ81_16570	COG4771	TonB-dependent receptor
ACZ81_16580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACZ81_16585	COG0778	Nitroreductase
ACZ81_16590	COG0596	Alpha beta hydrolase
ACZ81_16595	COG0251	oxidation-reduction process
ACZ81_16600	COG1335	isochorismatase
ACZ81_16605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACZ81_16610	COG1309	transcriptional regulator
ACZ81_16625	COG4628	conserved protein (DUF2132)
ACZ81_16630	COG2610	gluconate transmembrane transporter activity
ACZ81_16635	COG3265	gluconokinase activity
ACZ81_16640	COG1609	Transcriptional regulator
ACZ81_16645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACZ81_16655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACZ81_16675	COG1477	protein flavinylation
ACZ81_16680	COG2871	sodium ion transport
ACZ81_16685	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACZ81_16690	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACZ81_16695	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACZ81_16700	COG1805	sodium ion transport
ACZ81_16705	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACZ81_16710	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ACZ81_16715	COG0545	Peptidyl-prolyl cis-trans isomerase
ACZ81_16720	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ACZ81_16725	COG0039	L-malate dehydrogenase activity
ACZ81_16730	COG1438	arginine binding
ACZ81_16755	COG0572	uridine kinase
ACZ81_16760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACZ81_16775	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ACZ81_16785	COG0745	RESPONSE REGULATOR receiver
ACZ81_16785	COG3706	GGDEF domain
ACZ81_16795	COG0517	IMP dehydrogenase activity
ACZ81_16795	COG0516	GMP reductase activity
ACZ81_16800	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACZ81_16820	COG0189	ligase activity
ACZ81_16830	COG4067	protein conserved in archaea
ACZ81_16830	COG0189	ligase activity
ACZ81_16845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACZ81_16860	COG0667	Aldo Keto reductase
ACZ81_16915	COG0753	catalase activity
ACZ81_16925	COG5001	Diguanylate cyclase
ACZ81_16955	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ACZ81_16965	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACZ81_16970	COG0840	transmembrane signaling receptor activity
ACZ81_17020	COG0583	DNA-binding transcription factor activity
ACZ81_17040	COG1091	dTDP-4-dehydrorhamnose reductase activity
ACZ81_17075	COG1051	belongs to the nudix hydrolase family
ACZ81_17080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACZ81_17125	COG4584	PFAM Integrase catalytic
ACZ81_17130	COG1484	DNA-dependent DNA replication
ACZ81_17150	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ACZ81_17210	COG0110	maltose O-acetyltransferase activity
ACZ81_17250	COG0438	transferase activity, transferring glycosyl groups
ACZ81_17250	COG1216	Glycosyl transferase, family 2
ACZ81_17255	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ACZ81_17255	COG0662	Cupin 2, conserved barrel domain protein
ACZ81_17265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACZ81_17275	COG0202	RNA polymerase activity
ACZ81_17300	COG0201	protein transport
ACZ81_17320	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACZ81_17355	COG5002	protein histidine kinase activity
ACZ81_17355	COG0784	Response regulator, receiver
ACZ81_17375	COG0557	exoribonuclease II activity
ACZ81_17395	COG4771	TonB-dependent receptor
ACZ81_17420	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ACZ81_17445	COG2234	aminopeptidase activity
ACZ81_17455	COG4251	negative regulation of phosphorylation
ACZ81_17475	COG1271	oxidase subunit
ACZ81_17480	COG1294	oxidase, subunit
ACZ81_17490	COG1522	sequence-specific DNA binding
ACZ81_17500	COG1278	Cold shock
ACZ81_17505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACZ81_17515	COG2226	methyltransferase
ACZ81_17525	COG0339	signal peptide processing
ACZ81_17530	COG2201	protein-glutamate methylesterase activity
ACZ81_17540	COG3852	Histidine kinase
ACZ81_17550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACZ81_17555	COG0243	molybdopterin cofactor binding
ACZ81_17570	COG1506	peptidase
ACZ81_17570	COG4946	Tricorn protease homolog
ACZ81_17570	COG0823	Involved in the tonB-independent uptake of proteins
ACZ81_17615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ81_17625	COG2197	response regulator
ACZ81_17650	COG3385	transposase activity
ACZ81_17660	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ACZ81_17665	COG1278	Cold shock
ACZ81_17675	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACZ81_17680	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACZ81_17700	COG0281	malic enzyme
ACZ81_17710	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACZ81_17740	COG0456	acetyltransferase
ACZ81_17750	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ACZ81_17755	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ACZ81_17760	COG2177	Part of the ABC transporter FtsEX involved in
ACZ81_17765	COG2884	Cell division ATP-binding protein ftsE
ACZ81_17770	COG0552	protein localization to endoplasmic reticulum
ACZ81_17775	COG0742	ribosomal rna small subunit methyltransferase
ACZ81_17785	COG2095	MarC family integral membrane protein
ACZ81_17795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACZ81_17805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACZ81_17810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACZ81_17815	COG0617	tRNA 3'-terminal CCA addition
ACZ81_17820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACZ81_17835	COG0076	glutamate decarboxylase activity
ACZ81_17850	COG0842	Transport permease protein
ACZ81_17855	COG1131	(ABC) transporter
ACZ81_17860	COG0745	RESPONSE REGULATOR receiver
ACZ81_17865	COG2205	protein histidine kinase activity
ACZ81_17885	COG1253	flavin adenine dinucleotide binding
ACZ81_17890	COG0701	Predicted permease
ACZ81_17895	COG1966	Carbon starvation protein
ACZ81_17945	COG0848	biopolymer transport protein
ACZ81_17955	COG0811	peptide transport
ACZ81_17975	COG3128	pkhd-type hydroxylase
ACZ81_18000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACZ81_18005	COG0049	tRNA binding
ACZ81_18010	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACZ81_18015	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACZ81_18020	COG0085	RNA polymerase activity
ACZ81_18025	COG0222	ribosome binding
ACZ81_18030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACZ81_18035	COG0081	regulation of translation
ACZ81_18040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACZ81_18055	COG0250	Participates in transcription elongation, termination and antitermination
ACZ81_18060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACZ81_18070	COG1132	(ABC) transporter
ACZ81_18075	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACZ81_18080	COG3590	peptidase
ACZ81_18095	COG0513	Belongs to the DEAD box helicase family
ACZ81_18105	COG0418	dihydroorotase activity
ACZ81_18110	COG3040	lipid binding
ACZ81_18115	COG4989	oxidoreductase activity
ACZ81_18120	COG0346	lactoylglutathione lyase activity
ACZ81_18125	COG0668	transmembrane transport
ACZ81_18145	COG0302	gtp cyclohydrolase
ACZ81_18155	COG2957	Belongs to the agmatine deiminase family
ACZ81_18160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACZ81_18175	COG1201	RNA secondary structure unwinding
ACZ81_18180	COG2311	Membrane
ACZ81_18195	COG1793	dna ligase
ACZ81_18200	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACZ81_18205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACZ81_18230	COG0625	glutathione transferase activity
ACZ81_18235	COG0625	glutathione transferase activity
ACZ81_18245	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ACZ81_18250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACZ81_18260	COG1012	belongs to the aldehyde dehydrogenase family
ACZ81_18265	COG0028	Belongs to the TPP enzyme family
ACZ81_18275	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACZ81_18280	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ACZ81_18285	COG0330	HflC and HflK could
ACZ81_18290	COG0330	HflC and HflK could
ACZ81_18295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACZ81_18300	COG1923	regulation of RNA biosynthetic process
ACZ81_18305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACZ81_18310	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACZ81_18320	COG0802	atpase or kinase
ACZ81_18325	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACZ81_18325	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACZ81_18330	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACZ81_18340	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ACZ81_18350	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ACZ81_18355	COG0735	belongs to the Fur family
ACZ81_18365	COG0432	Pfam Uncharacterised protein family UPF0047
ACZ81_18375	COG0305	Participates in initiation and elongation during chromosome replication
ACZ81_18400	COG2258	MOSC domain
ACZ81_18440	COG3385	transposase activity
ACZ81_18475	COG0840	transmembrane signaling receptor activity
ACZ81_18480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ81_18480	COG4191	Histidine kinase
ACZ81_18485	COG0840	transmembrane signaling receptor activity
ACZ81_18500	COG2855	membrane
ACZ81_18505	COG2175	clavaminate synthase activity
ACZ81_18510	COG0656	L-ascorbic acid biosynthetic process
ACZ81_18530	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACZ81_18535	COG4771	TonB-dependent receptor
ACZ81_18555	COG3706	GGDEF domain
ACZ81_18565	COG1472	Belongs to the glycosyl hydrolase 3 family
ACZ81_18575	COG2723	6-phospho-beta-galactosidase activity
ACZ81_18580	COG1609	Transcriptional regulator
ACZ81_18585	COG0477	Major facilitator Superfamily
ACZ81_18585	COG2814	Major facilitator Superfamily
ACZ81_18590	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACZ81_18595	COG4988	ABC transporter
ACZ81_18600	COG1294	oxidase, subunit
ACZ81_18635	COG4319	ketosteroid isomerase
ACZ81_18645	COG4771	TonB-dependent receptor
ACZ81_18660	COG1469	GTP cyclohydrolase I activity
ACZ81_18700	COG3237	CsbD-like
ACZ81_18715	COG1595	DNA-templated transcription, initiation
ACZ81_18745	COG0596	Alpha beta hydrolase
ACZ81_18745	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACZ81_18770	COG3038	cytochrome b561
ACZ81_18780	COG1252	NADH dehydrogenase
ACZ81_18785	COG4206	TonB-dependent receptor
ACZ81_18800	COG0583	DNA-binding transcription factor activity
ACZ81_18810	COG2067	long-chain fatty acid transport protein
ACZ81_18815	COG2130	NADP-dependent
ACZ81_18820	COG2203	Gaf domain
ACZ81_18820	COG5001	Diguanylate cyclase
ACZ81_18820	COG4251	negative regulation of phosphorylation
ACZ81_18820	COG3706	GGDEF domain
ACZ81_18825	COG2205	protein histidine kinase activity
ACZ81_18825	COG0784	Response regulator, receiver
ACZ81_18835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACZ81_18840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACZ81_18845	COG1349	DNA-binding transcription factor activity
ACZ81_18850	COG0673	inositol 2-dehydrogenase activity
ACZ81_18865	COG0697	spore germination
ACZ81_18870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACZ81_18875	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACZ81_18880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACZ81_18885	COG1166	arginine decarboxylase activity
ACZ81_18895	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ACZ81_18900	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACZ81_18905	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACZ81_18975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACZ81_18985	COG0109	protoheme IX farnesyltransferase activity
ACZ81_19005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACZ81_19030	COG3866	Pectate lyase
ACZ81_19035	COG3344	reverse transcriptase
ACZ81_19090	COG1324	tolerance protein
ACZ81_19095	COG4232	protein-disulfide reductase activity
ACZ81_19100	COG0739	heme binding
ACZ81_19105	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACZ81_19110	COG0511	ligase activity, forming carbon-carbon bonds
ACZ81_19115	COG0439	Biotin carboxylase
ACZ81_19125	COG3344	reverse transcriptase
ACZ81_19170	COG0154	amidase activity
ACZ81_19185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACZ81_19190	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ACZ81_19205	COG0151	Belongs to the GarS family
ACZ81_19220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACZ81_19225	COG3954	Phosphoribulokinase
ACZ81_19235	COG0745	RESPONSE REGULATOR receiver
ACZ81_19250	COG1501	Belongs to the glycosyl hydrolase 31 family
ACZ81_19255	COG3344	reverse transcriptase
ACZ81_19265	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACZ81_19275	COG3031	protein transport across the cell outer membrane
ACZ81_19285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACZ81_19290	COG1459	type II secretion system
ACZ81_19295	COG2165	general secretion pathway protein
ACZ81_19300	COG2165	general secretion pathway protein
ACZ81_19305	COG2165	general secretion pathway protein
ACZ81_19310	COG4795	General secretion pathway protein
ACZ81_19325	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ACZ81_19345	COG1012	belongs to the aldehyde dehydrogenase family
ACZ81_19355	COG1011	Hydrolase
ACZ81_19360	COG0494	nUDIX hydrolase
ACZ81_19365	COG1218	3'(2'),5'-bisphosphate nucleotidase
ACZ81_19380	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ACZ81_19390	COG3089	Belongs to the UPF0270 family
ACZ81_19395	COG0429	hydrolase of the alpha beta-hydrolase fold
ACZ81_19405	COG0488	(ABC) transporter
ACZ81_19430	COG0545	Peptidyl-prolyl cis-trans isomerase
ACZ81_19440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACZ81_19445	COG2183	response to ionizing radiation
ACZ81_19465	COG0596	Alpha beta hydrolase
ACZ81_19470	COG1040	competence protein
ACZ81_19490	COG1794	racemase activity, acting on amino acids and derivatives
ACZ81_19505	COG0534	Mate efflux family protein
ACZ81_19520	COG1999	signal sequence binding
ACZ81_19525	COG0109	protoheme IX farnesyltransferase activity
ACZ81_19530	COG1612	heme a metabolic process
ACZ81_19555	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ACZ81_19560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACZ81_19565	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACZ81_19580	COG3706	GGDEF domain
ACZ81_19595	COG0129	dihydroxy-acid dehydratase activity
ACZ81_19600	COG2860	membrane
ACZ81_19605	COG0606	chelatase, subunit chli
ACZ81_19610	COG0583	DNA-binding transcription factor activity
ACZ81_19620	COG2814	Major facilitator Superfamily
ACZ81_19630	COG0729	surface antigen
ACZ81_19635	COG2911	Protein conserved in bacteria
ACZ81_19660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACZ81_19670	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACZ81_19695	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACZ81_19720	COG1228	amidohydrolase
ACZ81_19740	COG0425	Belongs to the sulfur carrier protein TusA family
ACZ81_19755	COG1561	YicC-like family, N-terminal region
ACZ81_19780	COG2211	Major facilitator Superfamily
ACZ81_19785	COG1609	Transcriptional regulator
ACZ81_19805	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ACZ81_19805	COG2199	diguanylate cyclase activity
ACZ81_19830	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ACZ81_19850	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACZ81_19855	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACZ81_19875	COG1475	DNA binding
ACZ81_19880	COG1192	Involved in chromosome partitioning
ACZ81_19895	COG3344	reverse transcriptase
ACZ81_19910	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACZ81_19915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACZ81_19925	COG0706	membrane insertase activity
ACZ81_19930	COG0594	ribonuclease P activity
ACZ81_19935	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACZ81_19985	COG0789	Transcriptional regulator
ACZ81_20215	COG0789	Transcriptional regulator
ACZ81_20230	COG1254	Belongs to the acylphosphatase family
ACZ81_20235	COG0409	Hydrogenase expression formation protein
ACZ81_20275	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ACZ81_20505	COG2197	response regulator
ACZ81_20575	COG1396	sequence-specific DNA binding
ACZ81_20705	COG0789	Transcriptional regulator