locus-tag	class	description
BM523_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BM523_00015	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BM523_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BM523_00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BM523_00045	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
BM523_00050	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
BM523_00055	ENOG4108R3E	Dna-3-methyladenine glycosylase i
BM523_00065	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
BM523_00075	ENOG4106RE7	Cytochrome
BM523_00080	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BM523_00085	ENOG4105C2M	dna polymerase I
BM523_00090	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
BM523_00095	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
BM523_00100	ENOG4105C1A	potassium transporter peripheral membrane
BM523_00105	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
BM523_00110	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BM523_00115	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BM523_00125	ENOG4105C79	DNA protecting protein DprA
BM523_00130	ENOG4108RPN	Protein smg homolog
BM523_00140	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BM523_00145	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
BM523_00150	ENOG4105EIF	outer membrane protein W
BM523_00160	ENOG4105E2X	shikimate dehydrogenase
BM523_00165	ENOG4108Z0R	Transferase
BM523_00210	ENOG4105C0B	DNA polymerase III (alpha subunit)
BM523_00240	ENOG4105IIU	Aminopeptidase
BM523_00250	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
BM523_00255	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
BM523_00260	ENOG4105W5Q	DNA repair protein (RadC
BM523_00280	ENOG4105E3R	(LipO)protein
BM523_00285	ENOG4105KDC	50s ribosomal protein l28
BM523_00290	ENOG4105W0E	50S ribosomal protein L33
BM523_00300	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BM523_00305	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BM523_00310	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
BM523_00315	ENOG4105DKP	glycosyl transferase, family 9
BM523_00330	ENOG4105BZU	Histidine kinase
BM523_00335	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BM523_00340	ENOG4105CPQ	Dehydrogenase
BM523_00345	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
BM523_00360	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
BM523_00365	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
BM523_00380	ENOG4105W0Z	cytoplasmic protein
BM523_00385	ENOG4105C4R	Atp-dependent dna helicase
BM523_00390	ENOG4105BZU	Histidine kinase
BM523_00395	ENOG4105MPD	Cytochrome
BM523_00415	ENOG4105DFD	Na H antiporter
BM523_00435	ENOG4108VCT	Sulfite exporter TauE/SafE
BM523_00450	ENOG4105UGU	tonB-dependent Receptor
BM523_00465	ENOG4108JJ8	(ABC) transporter
BM523_00470	ENOG4108JJ9	ABC, transporter
BM523_00480	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BM523_00485	ENOG4105VFE	sira family
BM523_00495	ENOG4105D3R	alkyl hydroperoxide reductase
BM523_00500	ENOG4105C94	Transporter
BM523_00525	ENOG4105DVF	Cytosine-specific methyltransferase
BM523_00530	ENOG41090BB	DNA mismatch endonuclease (vsr)
BM523_00560	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BM523_00570	ENOG4105D0S	secretion protein (HlyD
BM523_00575	ENOG4105CJ1	ABC, transporter
BM523_00580	ENOG4105CMI	transporter
BM523_00590	ENOG4107RNH	Outer membrane receptor FepA
BM523_00600	ENOG4105C1G	acyl-Coa dehydrogenase
BM523_00605	ENOG4105DQS	Transcriptional regulator
BM523_00615	ENOG4105CM6	amino acid regulated cytosolic protein
BM523_00630	ENOG4105D41	biosynthesis protein thiH
BM523_00635	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BM523_00645	ENOG4105D06	uba thif-type nad fad binding protein
BM523_00650	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
BM523_00655	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
BM523_00660	ENOG410601J	HemY protein
BM523_00665	ENOG4105ECF	c-methyltransferase
BM523_00670	ENOG41076E6	Uroporphyrinogen-III Synthase
BM523_00675	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
BM523_00680	ENOG4105BZU	Histidine kinase
BM523_00690	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BM523_00695	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BM523_00700	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BM523_00705	ENOG4105KME	endoribonuclease L-psp
BM523_00710	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
BM523_00715	ENOG4105CB5	ATP-dependent DNA helicase recG
BM523_00720	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
BM523_00740	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
BM523_00745	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BM523_00755	ENOG4105CBX	hi0933 family
BM523_00765	ENOG4105BZU	Histidine kinase
BM523_00770	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
BM523_00780	ENOG4105KPY	Small multidrug resistance protein
BM523_00795	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BM523_00800	ENOG4105BZS	acriflavin resistance protein
BM523_00810	ENOG4105CYC	Transferase
BM523_00830	ENOG4105C8Q	Methyl-accepting chemotaxis
BM523_00840	ENOG4108NST	exported protein
BM523_00845	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
BM523_00850	ENOG4105BZU	Histidine kinase
BM523_00865	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BM523_00870	ENOG4105CJW	magnesium transporter
BM523_00875	ENOG4105FR1	rard protein
BM523_00880	ENOG4105BZU	Histidine kinase
BM523_00885	ENOG4105C4R	Atp-dependent dna helicase
BM523_00890	ENOG4105D7W	serine acetyltransferase
BM523_00895	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
BM523_00900	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BM523_00910	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
BM523_00915	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
BM523_00935	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
BM523_00945	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
BM523_00950	ENOG4105DFU	Cell wall formation (By similarity)
BM523_00955	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BM523_00960	ENOG4105F0N	pyrophosphate phospho-hydrolase
BM523_00995	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BM523_01000	ENOG4107RDB	Major Facilitator
BM523_01005	ENOG4107VXZ	Hydrolase
BM523_01030	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
BM523_01035	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
BM523_01045	ENOG4107XMK	single-stranded DNA-binding protein
BM523_01070	ENOG4107RUZ	Sss sodium solute transporter superfamily
BM523_01090	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BM523_01095	ENOG4105E98	transcriptional regulator DeoR family
BM523_01100	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
BM523_01150	ENOG4107QHF	type ii secretion system protein e
BM523_01155	ENOG4105D7Q	type ii secretion system
BM523_01200	ENOG4105DFF	Rod shape-determining protein mreb
BM523_01205	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
BM523_01210	ENOG4105VQ7	Rod shape-determining protein MreD
BM523_01215	ENOG4108Z03	MAF-like protein
BM523_01220	ENOG4105C03	ribonuclease
BM523_01235	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
BM523_01240	ENOG4105N42	UPF0307 protein
BM523_01245	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
BM523_01255	ENOG4105CNT	hydrolase family 2
BM523_01260	ENOG41065U4	response regulator
BM523_01265	ENOG4105BZU	Histidine kinase
BM523_01270	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
BM523_01275	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
BM523_01280	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BM523_01285	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
BM523_01290	ENOG4105CEN	a g-specific adenine glycosylase
BM523_01295	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
BM523_01330	ENOG4105C8Q	Methyl-accepting chemotaxis
BM523_01335	ENOG4108VYJ	response regulator receiver protein
BM523_01340	ENOG4105CBS	Chea signal transduction histidine kinase
BM523_01345	ENOG4108V3W	Chemotaxis protein, CheW
BM523_01350	ENOG4107SDU	Methyl-accepting chemotaxis
BM523_01355	ENOG4105BZU	Histidine kinase
BM523_01360	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
BM523_01370	ENOG4105C8Q	Methyl-accepting chemotaxis
BM523_01375	ENOG4108VYJ	response regulator receiver protein
BM523_01380	ENOG4105CBS	Chea signal transduction histidine kinase
BM523_01385	ENOG4108V3W	Chemotaxis protein, CheW
BM523_01390	ENOG4107SDU	Methyl-accepting chemotaxis
BM523_01395	ENOG4107SDU	Methyl-accepting chemotaxis
BM523_01400	ENOG4105BZU	Histidine kinase
BM523_01405	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
BM523_01455	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BM523_01475	ENOG4105ETE	Transcriptional regulator (LacI family
BM523_01490	ENOG4105EAA	nucleoside
BM523_01515	ENOG4105C0A	alcohol dehydrogenase
BM523_01545	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BM523_01550	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BM523_01560	ENOG4107QM5	aconitate hydratase
BM523_01570	ENOG4107QHF	type ii secretion system protein e
BM523_01580	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BM523_01585	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BM523_01590	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BM523_01595	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BM523_01600	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BM523_01605	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BM523_01610	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BM523_01615	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BM523_01620	ENOG41083MP	50s ribosomal protein l29
BM523_01625	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BM523_01630	ENOG4107RJ7	Glycosyl transferase (Group 1
BM523_01640	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
BM523_01660	ENOG41069D7	Methyl-accepting chemotaxis
BM523_01665	ENOG4105DGW	oligopeptidase A
BM523_01685	ENOG4105CQ7	ATP-dependent helicase
BM523_01690	ENOG4105CVE	Lytic murein transglycosylase
BM523_01695	ENOG4105BZ4	penicillin-binding protein
BM523_01705	ENOG4105CKW	Inner membrane protein yedI
BM523_01715	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
BM523_01725	ENOG4108YZA	Nitrogen regulatory protein pii
BM523_01735	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BM523_01740	ENOG4105EZR	dyp-type peroxidase family protein
BM523_01750	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BM523_01755	ENOG4105CXT	aspartate transcarbamylase
BM523_01780	ENOG4105BZU	Histidine kinase
BM523_01785	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BM523_01795	ENOG4105BZU	Histidine kinase
BM523_01805	ENOG4105C26	Dehydrogenase
BM523_01815	ENOG4105C8Y	Acetylornithine aminotransferase
BM523_01830	ENOG4105C31	Tryptophanyl-tRNA synthetase
BM523_01835	ENOG4105DJV	ribulose-phosphate 3-epimerase
BM523_01855	ENOG4105DFE	Dna adenine methylase
BM523_01865	ENOG4105D49	3-dehydroquinate synthase
BM523_01870	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BM523_01875	ENOG4105E4G	Type IV pilus
BM523_01900	ENOG4108JQC	penicillin-binding protein 1A
BM523_01905	ENOG4107R1I	NAD-dependent malic enzyme
BM523_01915	ENOG4105CYM	Glutathione S-transferase
BM523_01925	ENOG4105CH6	catalase
BM523_01950	ENOG4105BZU	Histidine kinase
BM523_01955	ENOG4107QZM	n-acetylglutamate synthase
BM523_01960	ENOG4105CH7	arginosuccinase
BM523_01965	ENOG4105CDH	Citrulline--aspartate ligase
BM523_01975	ENOG4105CAS	nag kinase
BM523_01980	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
BM523_01985	ENOG4108Z5K	methylglyoxal synthase
BM523_01995	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
BM523_02010	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
BM523_02015	ENOG4105E0F	Histidine kinase
BM523_02020	ENOG4108EUD	Lysophospholipase
BM523_02025	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
BM523_02035	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BM523_02040	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
BM523_02045	ENOG4105VW4	glutaredoxin 3
BM523_02050	ENOG4107YZP	Rhodanese domain protein
BM523_02055	ENOG41063SB	peptidase
BM523_02060	ENOG4105PXI	polysaccharide deacetylase
BM523_02080	ENOG4105DJ4	phosphatidylserine decarboxylase
BM523_02085	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BM523_02090	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
BM523_02120	ENOG4105C7K	acetolactate synthase
BM523_02125	ENOG4108ZP8	Acetolactate synthase small subunit
BM523_02135	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
BM523_02140	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
BM523_02145	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
BM523_02155	ENOG4105F8V	Hydrolase, tatD family
BM523_02165	ENOG4105D52	delta-aminolevulinic acid dehydratase
BM523_02170	ENOG4105C9X	ppx gppa phosphatase
BM523_02175	ENOG4105C1J	atp-dependent rna helicase
BM523_02180	ENOG4105K63	Thioredoxin
BM523_02190	ENOG4105CH2	amidohydrolase
BM523_02195	ENOG4105BZU	Histidine kinase
BM523_02200	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
BM523_02205	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
BM523_02210	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
BM523_02235	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BM523_02245	ENOG4107QR8	Thioredoxin
BM523_02265	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BM523_02270	ENOG4105C26	Dehydrogenase
BM523_02285	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BM523_02290	ENOG4107S6Z	Na H antiporter
BM523_02305	ENOG4105EHZ	conserved protein UCP016719
BM523_02310	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BM523_02315	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BM523_02330	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
BM523_02345	ENOG4105K3M	)-transporter
BM523_02355	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
BM523_02360	ENOG4105I4A	GCN5-related N-acetyltransferase
BM523_02380	ENOG41084S7	Plasmid maintenance system antidote protein
BM523_02450	ENOG4105CHU	acetyl-coa acetyltransferase
BM523_02455	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BM523_02460	ENOG4107SC1	transglycosylase
BM523_02465	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
BM523_02475	ENOG4105EAH	synthase
BM523_02480	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BM523_02485	ENOG4105K46	50S ribosomal protein l27
BM523_02490	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BM523_02505	ENOG4108K5P	(LipO)protein
BM523_02510	ENOG4108UM1	dedA family
BM523_02515	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
BM523_02520	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
BM523_02525	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BM523_02530	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BM523_02535	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
BM523_02545	ENOG4105C8Q	Methyl-accepting chemotaxis
BM523_02580	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
BM523_02585	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
BM523_02590	ENOG4105HF0	Membrane
BM523_02595	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BM523_02600	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BM523_02605	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BM523_02610	ENOG4105BZU	Histidine kinase
BM523_02630	ENOG4105D3G	Pseudouridine synthase
BM523_02635	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
BM523_02650	ENOG4108IAB	Phoh family
BM523_02660	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BM523_02665	ENOG4105C1J	atp-dependent rna helicase
BM523_02680	ENOG4105DFG	type I secretion outer membrane protein
BM523_02685	ENOG41087AY	ADP-Ribose pyrophosphatase
BM523_02695	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
BM523_02700	ENOG4105IPS	esterase
BM523_02705	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BM523_02715	ENOG4107VXZ	Hydrolase
BM523_02740	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
BM523_02745	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BM523_02750	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
BM523_02755	ENOG4105UGU	tonB-dependent Receptor
BM523_02765	ENOG41068WN	
BM523_02770	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BM523_02775	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
BM523_02785	ENOG4105M85	Bola protein
BM523_02815	ENOG4105CHH	sulfate transporter
BM523_02820	ENOG4107QZF	nitrite reductase NADPH large subunit
BM523_02835	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BM523_02840	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BM523_02845	ENOG4107SDU	Methyl-accepting chemotaxis
BM523_02860	ENOG4105D7T	ABC transporter
BM523_02875	ENOG4108Z33	Thiol disulfide Interchange Protein
BM523_02880	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BM523_02885	ENOG4105E27	serine threonine protein kinase
BM523_02890	ENOG4105C58	cytochrome c oxidase accessory protein ccog
BM523_02905	ENOG4105CSU	acyl-Coa dehydrogenase
BM523_02910	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
BM523_02920	ENOG4105CXK	mandelate racemase muconate lactonizing
BM523_02925	ENOG4105MP9	class II Aldolase
BM523_02935	ENOG410624X	efflux transporter, rnd family, mfp subunit
BM523_02940	ENOG4105BZS	acriflavin resistance protein
BM523_02955	ENOG4105C8Q	Methyl-accepting chemotaxis
BM523_02960	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM523_02965	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BM523_02970	ENOG4105KTH	gatB Yqey
BM523_02975	ENOG4105VCC	30S ribosomal protein S21
BM523_02980	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BM523_02990	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
BM523_02995	ENOG4107ZVW	dihydroneopterin aldolase
BM523_03005	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BM523_03010	ENOG4105K59	histidine triad (HIT) protein
BM523_03025	ENOG4105DKK	Benzoate
BM523_03030	ENOG4108JCI	Transcriptional regulator
BM523_03035	ENOG4105DH7	May be involved in recombination (By similarity)
BM523_03040	ENOG4105BZU	Histidine kinase
BM523_03045	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BM523_03050	ENOG4105BZU	Histidine kinase
BM523_03085	ENOG4109015	Biopolymer transport protein exbD tolR
BM523_03090	ENOG41067XB	TonB family
BM523_03100	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BM523_03105	ENOG4105BZU	Histidine kinase
BM523_03110	ENOG4105CEY	Amp-dependent synthetase and ligase
BM523_03125	ENOG4107QIJ	Aconitate hydratase 2
BM523_03130	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BM523_03150	ENOG4107QIJ	Aconitate hydratase 2
BM523_03160	ENOG4105CFH	Aspartokinase
BM523_03165	ENOG4108NVR	Methyl-accepting chemotaxis
BM523_03170	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
BM523_03175	ENOG4105NWN	ApaG protein
BM523_03180	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BM523_03185	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
BM523_03190	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
BM523_03195	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
BM523_03200	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
BM523_03205	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BM523_03210	ENOG4105T95	Thiol disulfide interChange protein
BM523_03215	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BM523_03225	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
BM523_03230	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
BM523_03235	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
BM523_03240	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BM523_03245	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BM523_03250	ENOG4105DXN	mazG family
BM523_03270	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BM523_03275	ENOG4108UJD	30S ribosomal protein S9
BM523_03280	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BM523_03285	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BM523_03290	ENOG4105EIX	cytochrome c1
BM523_03295	ENOG4107MKT	Stringent starvation protein a
BM523_03300	ENOG4105KB2	stringent starvation protein b
BM523_03315	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BM523_03320	ENOG4105CJW	magnesium transporter
BM523_03325	ENOG41080Z8	PHOSPHOCARRIER protein
BM523_03330	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
BM523_03335	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
BM523_03340	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
BM523_03345	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM523_03350	ENOG4108IUZ	ABC transporter
BM523_03355	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
BM523_03365	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
BM523_03370	ENOG4105C2X	Arabinose 5-phosphate isomerase
BM523_03380	ENOG4105DHJ	ABC, transporter
BM523_03385	ENOG4105CY3	ABC transporter, permease
BM523_03390	ENOG4107PE3	Mammalian cell entry related domain protein
BM523_03395	ENOG4105E3I	toluene tolerance
BM523_03405	ENOG4105VFK	BolA family
BM523_03410	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BM523_03415	ENOG4105C0H	protease
BM523_03420	ENOG4105C0H	protease
BM523_03430	ENOG4105D6Z	AFG1 family ATPase
BM523_03435	ENOG4105CDY	transcriptional regulatory protein
BM523_03450	ENOG4105BZU	Histidine kinase
BM523_03455	ENOG4108RCM	Nitroreductase
BM523_03465	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BM523_03480	ENOG4105D05	Receptor
BM523_03485	ENOG4108RNG	Permease of the drug metabolite transporter
BM523_03490	ENOG4105BZU	Histidine kinase
BM523_03510	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BM523_03515	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BM523_03520	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BM523_03525	ENOG4105BZA	Phosphoglycerate kinase
BM523_03530	ENOG4105WYW	fructose-bisphosphate aldolase
BM523_03540	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BM523_03545	ENOG4105C9X	ppx gppa phosphatase
BM523_03560	ENOG4105C8U	phosphate abc transporter
BM523_03570	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BM523_03580	ENOG4105CJ3	phosphate transporter
BM523_03590	ENOG4105C5Q	Transcriptional regulator
BM523_03600	ENOG4108UT2	hemolysin iii
BM523_03605	ENOG4105K56	Transcriptional regulator
BM523_03610	ENOG4108ZHJ	Organic hydroperoxide resistance protein
BM523_03625	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
BM523_03635	ENOG4107SDU	Methyl-accepting chemotaxis
BM523_03645	ENOG4105HEI	LysR family (Transcriptional regulator
BM523_03650	ENOG4107QM2	Aldo Keto reductase
BM523_03665	ENOG4107RH8	nuclease SbcCD subunit D
BM523_03670	ENOG4105EYH	Exonuclease
BM523_03680	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
BM523_03700	ENOG4105CI2	imidazolone-5-propionate hydrolase
BM523_03705	ENOG4105CZE	histidine utilization repressor
BM523_03710	ENOG4105CGP	Urocanate hydratase
BM523_03715	ENOG4105C84	Histidine ammonia-lyase
BM523_03740	ENOG4105C5H	ABC transporter
BM523_03765	ENOG4105D64	Mechanosensitive ion channel
BM523_03790	ENOG4108NSC	Pfam:DUF88
BM523_03825	ENOG41067MG	lrgb family
BM523_03855	ENOG4105CSA	Coproporphyrinogen iii oxidase
BM523_03865	ENOG4105C1J	atp-dependent rna helicase
BM523_03870	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BM523_03885	ENOG4105CPI	Metal Dependent Phosphohydrolase
BM523_03890	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BM523_03895	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BM523_03900	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BM523_03905	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BM523_03920	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BM523_03925	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BM523_03930	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BM523_03940	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BM523_03945	ENOG4108IUW	ABC transporter
BM523_03950	ENOG4108SDH	ABC, transporter
BM523_03960	ENOG4107EXC	regulatoR
BM523_03990	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
BM523_03995	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
BM523_04000	ENOG41060IM	Heme exporter protein
BM523_04005	ENOG4105X3C	heme exporter protein
BM523_04010	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
BM523_04015	ENOG4105DA4	cytochrome c-type biogenesis protein
BM523_04020	ENOG4107QX9	Thiol disulfide interChange protein
BM523_04025	ENOG4108M1T	Cytochrome c-type biogenesis protein
BM523_04035	ENOG410903C	(LipO)protein
BM523_04040	ENOG4105CMR	udp-glucose 4-epimerase
BM523_04050	ENOG4105DUX	Transporter
BM523_04080	ENOG4105ESV	Glycosyl transferase, family 4
BM523_04095	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BM523_04100	ENOG4105KQC	Competence protein
BM523_04105	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BM523_04120	ENOG4105EWT	decarboxylase family
BM523_04125	ENOG4105BZU	Histidine kinase
BM523_04130	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
BM523_04135	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
BM523_04170	ENOG4105DR9	pseudouridine synthase
BM523_04175	ENOG4105QDK	Flavodoxin
BM523_04180	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
BM523_04185	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
BM523_04190	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BM523_04195	ENOG4105CE9	30S ribosomal protein S2
BM523_04200	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BM523_04205	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BM523_04210	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BM523_04215	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BM523_04220	ENOG4105KNE	Phosphatidate cytidylyltransferase
BM523_04225	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
BM523_04235	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM523_04240	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
BM523_04245	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BM523_04250	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BM523_04255	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BM523_04260	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BM523_04265	ENOG4105C0B	DNA polymerase III (alpha subunit)
BM523_04270	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
BM523_04275	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BM523_04280	ENOG4105BZU	Histidine kinase
BM523_04295	ENOG4108Z6B	deaminase
BM523_04300	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
BM523_04305	ENOG4108ETH	Formylglycinamide ribotide synthetase
BM523_04310	ENOG4108DG9	Smr protein MutS2
BM523_04335	ENOG4105CDV	Ompa motb domain protein
BM523_04340	ENOG4108JJA	ABC, transporter
BM523_04350	ENOG4105WH1	Two component transcriptional regulator luxr family
BM523_04390	ENOG4107R88	Chemotaxis protein (CheV)
BM523_04395	ENOG4105BZU	Histidine kinase
BM523_04400	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
BM523_04405	ENOG4108ZC9	flagellar basal-body rod protein flgc
BM523_04410	ENOG4105W00	Flagellar hook capping protein
BM523_04415	ENOG4105BZE	flagellar hook protein, FlgE
BM523_04420	ENOG4108KPB	Flagellar basal-body rod protein FlgF
BM523_04425	ENOG4105CGA	flagellar basal-body rod protein FlgG
BM523_04430	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
BM523_04435	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
BM523_04440	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
BM523_04445	ENOG4105E1Q	flagellar hook-associated protein
BM523_04460	ENOG4105I03	Flagellin
BM523_04465	ENOG4105I03	Flagellin
BM523_04470	ENOG4105I03	Flagellin
BM523_04475	ENOG41063QE	flagellar protein FlaG
BM523_04485	ENOG4105MQ3	flagellar protein FliS
BM523_04500	ENOG4108IAJ	Nad-dependent epimerase dehydratase
BM523_04505	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BM523_04520	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
BM523_04535	ENOG4108TN2	lmbE family
BM523_04545	ENOG4105D2T	synthase
BM523_04555	ENOG4108S0S	Nucleotidyl transferase
BM523_04560	ENOG4105F0R	Cytidylyltransferase
BM523_04575	ENOG4105CHR	reductase
BM523_04580	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BM523_04595	ENOG4105D2T	synthase
BM523_04605	ENOG4105F0R	Cytidylyltransferase
BM523_04610	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BM523_04615	ENOG4105C5E	polysaccharide biosynthesis protein
BM523_04620	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
BM523_04630	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM523_04635	ENOG4105BZU	Histidine kinase
BM523_04640	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM523_04645	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
BM523_04650	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
BM523_04655	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BM523_04665	ENOG4108JIR	Flagellum-specific ATP synthase
BM523_04685	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BM523_04690	ENOG4105DD5	Flagellar motor switch protein
BM523_04695	ENOG4105VTB	flagellar biosynthesis protein fliO
BM523_04700	ENOG4105CN7	Flagellar biosynthetic protein FliP
BM523_04705	ENOG4105VS8	Flagellar biosynthetic protein fliq
BM523_04710	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
BM523_04715	ENOG4105D00	flagellar biosynthetic protein flhB
BM523_04720	ENOG4105D7B	Flagellar biosynthesis protein flha
BM523_04725	ENOG4105FZW	flagellar biosynthesis regulator FlhF
BM523_04735	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM523_04740	ENOG4108VYJ	response regulator receiver protein
BM523_04745	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
BM523_04750	ENOG4105CBS	Chea signal transduction histidine kinase
BM523_04760	ENOG4107QJE	Chromosome Partitioning Protein
BM523_04770	ENOG4105YFD	chemotaxis, protein
BM523_04780	ENOG4105CVG	Homoserine O-transsuccinylase
BM523_04785	ENOG4105C3R	Methionine synthase
BM523_04790	ENOG4105C3R	Methionine synthase
BM523_04800	ENOG4105NBK	UPF0345 protein
BM523_04805	ENOG4105C8Q	Methyl-accepting chemotaxis
BM523_04810	ENOG4105DZ2	Transcriptional regulator
BM523_04815	ENOG4105C5Q	Transcriptional regulator
BM523_04820	ENOG4107B2H	carbonic anhydrase
BM523_04825	ENOG4105CHH	sulfate transporter
BM523_04840	ENOG4105C9K	Endothelin-converting enzyme 1
BM523_04850	ENOG4108004	Modulates RecA activity (By similarity)
BM523_04855	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BM523_04860	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
BM523_04885	ENOG4107QSA	Oxaloacetate decarboxylase
BM523_04890	ENOG4105D9Q	decarboxylase (Beta subunit)
BM523_04895	ENOG4108JQ2	peptide transport system atp-binding protein
BM523_04900	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
BM523_04905	ENOG4108EU3	peptide transport system, permease
BM523_04910	ENOG4108I5W	peptide transport system, permease protein
BM523_04915	ENOG4105DEF	Extracellular solute-binding protein, family 5
BM523_04920	ENOG4105E51	psp operon transcriptional activator
BM523_04925	ENOG41087YS	Phage shock protein A
BM523_04940	ENOG4105MIR	Phenylalanine 4-monooxygenase
BM523_04955	ENOG4108RXX	maleylacetoacetate isomerase
BM523_04960	ENOG4108XM1	transcriptional regulator AsnC family
BM523_04980	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
BM523_04985	ENOG4108KPZ	tonB-dependent Receptor
BM523_05035	ENOG4109015	Biopolymer transport protein exbD tolR
BM523_05040	ENOG410822N	TonB family
BM523_05050	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
BM523_05090	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
BM523_05105	ENOG4105HEI	LysR family (Transcriptional regulator
BM523_05110	ENOG4105F27	Major Facilitator
BM523_05115	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
BM523_05120	ENOG4105CV8	reductase
BM523_05130	ENOG4105BZU	Histidine kinase
BM523_05135	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
BM523_05140	ENOG4105C75	arginyL-tRNA synthetase
BM523_05190	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
BM523_05200	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BM523_05205	ENOG4105CRK	lysyL-tRNA synthetase
BM523_05215	ENOG4108W1A	pseudouridine synthase
BM523_05230	ENOG4105D9M	gamma-glutamylcysteine synthetase
BM523_05245	ENOG4108DG9	Smr protein MutS2
BM523_05250	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
BM523_05255	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BM523_05265	ENOG4105ED1	spovr family
BM523_05270	ENOG4106AKX	UPF0229 protein
BM523_05275	ENOG4105CYN	Serine protein kinase
BM523_05280	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BM523_05285	ENOG4105M2J	Glutaredoxin
BM523_05290	ENOG4105D05	Receptor
BM523_05315	ENOG4105D3R	alkyl hydroperoxide reductase
BM523_05320	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
BM523_05325	ENOG4105EIY	sodium-type flagellar protein motY
BM523_05330	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
BM523_05335	ENOG4108UYE	Lactoylglutathione lyase
BM523_05340	ENOG4105VEQ	Cold shock protein
BM523_05360	ENOG4105DZB	Electron transport complex
BM523_05365	ENOG4108UQQ	Electron transport complex
BM523_05370	ENOG4105D6A	Electron transport complex
BM523_05380	ENOG4108R3D	Electron transport complex
BM523_05385	ENOG4105DGN	Electron transport complex
BM523_05400	ENOG4107QJQ	Mate efflux family protein
BM523_05405	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BM523_05415	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
BM523_05420	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
BM523_05430	ENOG4105CAQ	asparagine synthetase
BM523_05460	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
BM523_05465	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
BM523_05470	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
BM523_05475	ENOG4105C11	sulfate adenylyltransferase), subunit 2
BM523_05480	ENOG4105CK7	Sodium proline symporter
BM523_05485	ENOG4105BZU	Histidine kinase
BM523_05530	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BM523_05535	ENOG4105CHU	acetyl-coa acetyltransferase
BM523_05540	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BM523_05550	ENOG4105BZU	Histidine kinase
BM523_05560	ENOG4108BY2	phosphohistidine phosphatase
BM523_05570	ENOG4108JU6	CBS domain protein
BM523_05575	ENOG4106KVJ	cytochrome C assembly protein
BM523_05580	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BM523_05625	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
BM523_05630	ENOG4105BZ1	(ABC) transporter
BM523_05645	ENOG4105K5M	30s ribosomal protein S16
BM523_05650	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BM523_05655	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BM523_05660	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BM523_05665	ENOG4105EN6	Membrane
BM523_05670	ENOG4105E39	Enoyl-CoA hydratase
BM523_05675	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
BM523_05695	ENOG4108ZJT	translation initiation factor, Sui1
BM523_05705	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BM523_05715	ENOG4105BZU	Histidine kinase
BM523_05725	ENOG4107WP9	Histidine kinase
BM523_05735	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM523_05740	ENOG4105I03	Flagellin
BM523_05755	ENOG4105C9M	aspartyl-trna synthetase
BM523_05760	ENOG4108TIT	dATP pyrophosphohydrolase
BM523_05765	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
BM523_05770	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BM523_05775	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BM523_05780	ENOG4107YD3	Thioesterase
BM523_05785	ENOG4105E02	MotA TolQ exbB proton channel
BM523_05790	ENOG4105M8F	Biopolymer transport protein exbD tolR
BM523_05800	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
BM523_05805	ENOG4105KCK	Peptidoglycan-associated lipoprotein
BM523_05810	ENOG4105UFD	tol-pal system protein YbgF
BM523_05830	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
BM523_05845	ENOG4108NRW	Phospholipase, patatin family
BM523_05850	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
BM523_05865	ENOG4108W6C	Dehydrogenase
BM523_05870	ENOG4105DS1	cytochrome b561
BM523_05885	ENOG4105BZU	Histidine kinase
BM523_05900	ENOG4105HEI	LysR family (Transcriptional regulator
BM523_05905	ENOG4105DQ4	alcohol dehydrogenase
BM523_05910	ENOG4108VKG	metal-dependent hydrolase
BM523_05915	ENOG4105BZS	acriflavin resistance protein
BM523_05925	ENOG4108XG4	DNA-binding transcriptional regulator
BM523_05930	ENOG4108ESX	Receptor
BM523_05950	ENOG4105BZU	Histidine kinase
BM523_05960	ENOG4105DY2	Paraquat-inducible protein b
BM523_05965	ENOG4105F1S	paraquat-inducible protein a
BM523_05980	ENOG4105EMU	Dehydrogenase
BM523_05985	ENOG4105CF7	AraC family transcriptional regulator
BM523_05990	ENOG4105C5S	asparaginyl-tRNA synthetase
BM523_06005	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
BM523_06025	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
BM523_06030	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
BM523_06035	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BM523_06040	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
BM523_06045	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
BM523_06050	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
BM523_06055	ENOG4105KJF	protein tyrosine phosphatase
BM523_06060	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
BM523_06065	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
BM523_06070	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
BM523_06085	ENOG4108JJ7	ABC transporter
BM523_06090	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BM523_06100	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BM523_06120	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BM523_06155	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
BM523_06170	ENOG4108UJV	acyl-CoA thioesterase i
BM523_06175	ENOG4108I0Y	(ABC) transporter
BM523_06180	ENOG4105CV6	ABC transporter, permease
BM523_06185	ENOG4105ECP	epimerase
BM523_06190	ENOG4105KKP	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
BM523_06195	ENOG4105DSF	transport protein
BM523_06205	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BM523_06220	ENOG4105K9H	YciI-like protein
BM523_06225	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
BM523_06230	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BM523_06235	ENOG4105DK0	Indole-3-glycerol phosphate synthase
BM523_06240	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BM523_06250	ENOG4105CRQ	synthase (Component I)
BM523_06255	ENOG4105DB7	PHP domain protein
BM523_06260	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
BM523_06265	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
BM523_06270	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
BM523_06275	ENOG4105FE9	pseudouridine synthase
BM523_06280	ENOG4105CV8	reductase
BM523_06285	ENOG4108UW5	maltose o-acetyltransferase
BM523_06295	ENOG4106BRA	Membrane
BM523_06310	ENOG4108JJ6	Type I secretion system ATPase
BM523_06320	ENOG4105FQ6	thiopurine methyltransferase
BM523_06325	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BM523_06330	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BM523_06335	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
BM523_06340	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BM523_06345	ENOG4105C0A	alcohol dehydrogenase
BM523_06350	ENOG4105DTD	Dehydrogenase
BM523_06360	ENOG4105DWV	Homoserine O-trans-acetylase
BM523_06365	ENOG4105CY2	Citrate transporter
BM523_06380	ENOG4105BZU	Histidine kinase
BM523_06400	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BM523_06405	ENOG4105CFG	Acts as a chaperone (By similarity)
BM523_06410	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BM523_06415	ENOG41085AF	Cytochrome
BM523_06425	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BM523_06435	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
BM523_06440	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BM523_06445	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
BM523_06450	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BM523_06470	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
BM523_06475	ENOG4105C6K	Malic enzyme
BM523_06490	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
BM523_06495	ENOG4108JU5	Magnesium and cobalt efflux protein
BM523_06500	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BM523_06505	ENOG4105C9A	Phoh family
BM523_06510	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BM523_06515	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
BM523_06540	ENOG4107RNH	Outer membrane receptor FepA
BM523_06545	ENOG4108S4H	thioesterase Superfamily protein
BM523_06550	ENOG4107XWI	flavin reductase domain protein, FMN-binding
BM523_06605	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BM523_06610	ENOG4105C3G	gtp-binding protein
BM523_06615	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BM523_06620	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BM523_06625	ENOG4105DQ4	alcohol dehydrogenase
BM523_06640	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BM523_06650	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BM523_06655	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
BM523_06660	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
BM523_06665	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BM523_06670	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BM523_06675	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BM523_06680	ENOG4108YY7	Invasion gene expression up-regulator SirB
BM523_06685	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
BM523_06695	ENOG4105ETT	transcriptional Regulator, LysR family
BM523_06705	ENOG4105M08	Membrane
BM523_06710	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
BM523_06715	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BM523_06720	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
BM523_06725	ENOG4107TPY	serine threonine protein kinase
BM523_06730	ENOG4105TMB	Formate nitrite transporter
BM523_06735	ENOG4105F8C	transglutaminase domain-containing protein
BM523_06745	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BM523_06750	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
BM523_06755	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
BM523_06760	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
BM523_06765	ENOG4105BZU	Histidine kinase
BM523_06770	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
BM523_06780	ENOG4105K8R	UPF0145 protein
BM523_06800	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BM523_06805	ENOG4105KUZ	arsenate reductase
BM523_06810	ENOG4107RBJ	symporter
BM523_06830	ENOG4105F1J	Homogentisate 1,2-dioxygenase
BM523_06850	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BM523_06860	ENOG4105BZU	Histidine kinase
BM523_06865	ENOG4105BZU	Histidine kinase
BM523_06885	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
BM523_06910	ENOG4105BZU	Histidine kinase
BM523_06920	ENOG4107QUY	Guanine deaminase
BM523_06940	ENOG4105C7W	Xanthine dehydrogenase
BM523_06955	ENOG4108R86	Transcriptional regulator
BM523_06970	ENOG4105C7N	Xanthine uracil vitamin C permease
BM523_06975	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
BM523_06985	ENOG4105BZU	Histidine kinase
BM523_06995	ENOG4105BZU	Histidine kinase
BM523_07005	ENOG4105C2W	permease
BM523_07020	ENOG4105C5R	Aminotransferase
BM523_07025	ENOG4105HF0	Membrane
BM523_07030	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BM523_07065	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
BM523_07075	ENOG4105C22	threonyL-tRNA synthetase
BM523_07080	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BM523_07085	ENOG41082NX	50s ribosomal protein l35
BM523_07090	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BM523_07100	ENOG4105D3Q	Sugar transferase
BM523_07110	ENOG4105DAY	polysaccharide export protein
BM523_07115	ENOG4108QV3	biosynthesis protein
BM523_07120	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
BM523_07145	ENOG4105BZU	Histidine kinase
BM523_07155	ENOG4107QPH	glycogen) synthase
BM523_07185	ENOG4107T8Q	Glycosyl transferase (Group 1
BM523_07190	ENOG4105C74	pyruvyl transferase
BM523_07210	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BM523_07215	ENOG4105JEU	Glycosyl transferase, family 2
BM523_07220	ENOG4105EXC	Acyl-transferase
BM523_07235	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BM523_07240	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BM523_07245	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
BM523_07255	ENOG4108Z66	YbaK ebsC protein
BM523_07265	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
BM523_07270	ENOG4108WBT	adenosyltransferase
BM523_07280	ENOG4108JA2	transcriptioN-repair coupling factor
BM523_07290	ENOG4105D60	lipoprotein releasing system transmembrane protein
BM523_07315	ENOG4105CGK	Exodeoxyribonuclease III
BM523_07350	ENOG4105DNH	Major Facilitator
BM523_07360	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
BM523_07380	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
BM523_07390	ENOG4108UKI	Enoyl-CoA hydratase
BM523_07395	ENOG4107QX3	carboxylase
BM523_07400	ENOG4105C1G	acyl-Coa dehydrogenase
BM523_07405	ENOG4108Z6Z	Transcriptional regulator
BM523_07410	ENOG4105CHU	acetyl-coa acetyltransferase
BM523_07425	ENOG4105BZU	Histidine kinase
BM523_07435	ENOG4105CJB	Exodeoxyribonuclease I
BM523_07440	ENOG4105BZU	Histidine kinase
BM523_07445	ENOG4105D44	asparaginase
BM523_07485	ENOG4105CQ7	ATP-dependent helicase
BM523_07500	ENOG4105DR4	Methyltransferase
BM523_07505	ENOG4108JA1	polyketide synthase
BM523_07510	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BM523_07515	ENOG4107RZZ	dna polymerase iii epsilon subunit
BM523_07545	ENOG4108M8H	domain protein
BM523_07555	ENOG4105D60	lipoprotein releasing system transmembrane protein
BM523_07560	ENOG4105CK2	sodium dicarboxylate symporter
BM523_07570	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
BM523_07580	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BM523_07595	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
BM523_07600	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
BM523_07605	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
BM523_07625	ENOG4105JQN	Transcriptional regulator
BM523_07630	ENOG4107YB6	acetyltransferase, (GNAT) family
BM523_07645	ENOG4105C03	ribonuclease
BM523_07650	ENOG4105EI2	Pseudouridine synthase
BM523_07665	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
BM523_07670	ENOG4105VGS	50s ribosomal protein l32
BM523_07675	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
BM523_07680	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BM523_07685	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
BM523_07690	ENOG4105CHR	reductase
BM523_07695	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BM523_07700	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BM523_07710	ENOG4105HHA	aminodeoxychorismate lyase
BM523_07715	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BM523_07720	ENOG4107QRG	dna polymerase iii
BM523_07725	ENOG4105F8V	Hydrolase, tatD family
BM523_07740	ENOG4105BZU	Histidine kinase
BM523_07760	ENOG4105CHR	reductase
BM523_07765	ENOG4108J2P	Alpha beta hydrolase fold
BM523_07775	ENOG4105CHU	acetyl-coa acetyltransferase
BM523_07780	ENOG4105CSU	acyl-Coa dehydrogenase
BM523_07795	ENOG4105DKT	Transcriptional regulator
BM523_07800	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
BM523_07810	ENOG4105DEI	Mannitol dehydrogenase
BM523_07835	ENOG4105D8X	mechanosensitive ion channel
BM523_07840	ENOG4105D05	Receptor
BM523_07845	ENOG4105KZX	Pterin carbinolamine dehydratase
BM523_07865	ENOG4105BZU	Histidine kinase
BM523_07870	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BM523_07875	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
BM523_07880	ENOG4105CHV	Transcription elongation factor NusA
BM523_07885	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BM523_07890	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BM523_07895	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BM523_07905	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BM523_07910	ENOG4105BZU	Histidine kinase
BM523_07915	ENOG4105FE9	pseudouridine synthase
BM523_07925	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
BM523_07955	ENOG4105D3R	alkyl hydroperoxide reductase
BM523_07995	ENOG4105CCT	upf0313 protein
BM523_08010	ENOG4105D05	Receptor
BM523_08015	ENOG4107QN2	dihydrolipoyl dehydrogenase
BM523_08025	ENOG4105VNH	ABC transporter solute-binding protein
BM523_08035	ENOG4108VGW	abc transporter atp-binding protein
BM523_08040	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
BM523_08080	ENOG4105CBN	LysR family transcriptional regulator
BM523_08100	ENOG4105CJ1	ABC, transporter
BM523_08115	ENOG4105DMT	epimerase dehydratase
BM523_08120	ENOG4105C09	Bile acid
BM523_08180	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BM523_08185	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BM523_08190	ENOG4108Z1B	Cyclase dehydrase
BM523_08195	ENOG4105VDB	UPF0125 protein
BM523_08205	ENOG4105C94	Transporter
BM523_08215	ENOG4107RDJ	Sulfotransferase
BM523_08225	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
BM523_08230	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
BM523_08265	ENOG4105EZE	Cupin 4 family protein
BM523_08275	ENOG4107QTF	adenylosuccinate lyase
BM523_08280	ENOG41075W9	High frequency lysogenization protein HflD homolog
BM523_08285	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BM523_08290	ENOG4108R99	pseudouridine synthase
BM523_08295	ENOG4105E9K	Isocitrate dehydrogenase
BM523_08300	ENOG4105VEQ	Cold shock protein
BM523_08305	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
BM523_08310	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BM523_08315	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BM523_08320	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
BM523_08325	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
BM523_08330	ENOG4105C3M	thioredoxin reductase
BM523_08335	ENOG4105PQ6	UPF0208 membrane protein
BM523_08340	ENOG4105GPY	SprT protein
BM523_08345	ENOG4105D07	Signal peptide peptidase, SppA
BM523_08360	ENOG41069NU	Nitroreductase
BM523_08370	ENOG4105HDK	L-asparaginase
BM523_08375	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
BM523_08380	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
BM523_08385	ENOG4108Z43	UPF0250 protein
BM523_08390	ENOG4105DZ1	carboxypeptidase
BM523_08395	ENOG4105K6T	rare lipoprotein A
BM523_08400	ENOG4105CNI	cell division protein FtsW
BM523_08405	ENOG4105CJN	penicillin-binding protein
BM523_08410	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
BM523_08415	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
BM523_08425	ENOG4105DJF	DNA polymerase III, delta' subunit
BM523_08430	ENOG4108U2H	Rare lipoprotein B
BM523_08435	ENOG4105C8T	Leucyl-tRNA synthetase
BM523_08445	ENOG4105DAN	ATP-dependent protease
BM523_08450	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
BM523_08455	ENOG4105BZU	Histidine kinase
BM523_08465	ENOG4105HBR	Rna-binding protein
BM523_08470	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
BM523_08475	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BM523_08480	ENOG4105EEI	dihydropteroate synthase
BM523_08485	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BM523_08490	ENOG4105CP7	Triose-phosphate isomerase
BM523_08505	ENOG4105BZU	Histidine kinase
BM523_08535	ENOG4105CHR	reductase
BM523_08540	ENOG4108KP7	hydrolase
BM523_08555	ENOG4105CK7	Sodium proline symporter
BM523_08565	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BM523_08580	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BM523_08610	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BM523_08695	ENOG410822N	TonB family
BM523_08725	ENOG4105EXN	Sulfate transport protein CysZ
BM523_08730	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
BM523_08735	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
BM523_08740	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BM523_08755	ENOG4105BZ1	(ABC) transporter
BM523_08760	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
BM523_08765	ENOG4105W49	UPF0434 protein
BM523_08770	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
BM523_08780	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
BM523_08795	ENOG4105CUZ	uba thif-type nad fad binding protein
BM523_08800	ENOG4105CHF	Glutathione S-transferase
BM523_08805	ENOG4105EUB	pirin domain protein
BM523_08810	ENOG4107QKV	phosphomannomutase
BM523_08820	ENOG4105BZN	citrate synthase
BM523_08825	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
BM523_08830	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
BM523_08835	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
BM523_08840	ENOG4105E33	succinate dehydrogenase
BM523_08845	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
BM523_08850	ENOG4105C7S	Dehydrogenase
BM523_08855	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
BM523_08860	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
BM523_08880	ENOG4105QV4	Tryptophan halogenase
BM523_08895	ENOG4108NRW	Phospholipase, patatin family
BM523_08915	ENOG4108IUK	alpha amylase, catalytic
BM523_08930	ENOG4105ETE	Transcriptional regulator (LacI family
BM523_08935	ENOG4105CX6	glutaminyL-tRNA synthetase
BM523_08940	ENOG4105UBK	short-chain dehydrogenase reductase
BM523_08945	ENOG4108M0H	Extracellular lipase
BM523_08950	ENOG4107SQI	penicillin amidase
BM523_08955	ENOG4105ERU	peptidase
BM523_08970	ENOG4107QNR	UPF0135 protein
BM523_08975	ENOG4106371	Methyltransferase
BM523_08980	ENOG4105C5I	Dehydrogenase
BM523_08985	ENOG4108V06	Glutathione peroxidase
BM523_08990	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BM523_09000	ENOG4105C1G	acyl-Coa dehydrogenase
BM523_09005	ENOG4105E39	Enoyl-CoA hydratase
BM523_09010	ENOG4105DHI	Methyltransferase
BM523_09015	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
BM523_09020	ENOG4105E68	Sulfatase
BM523_09025	ENOG4105YDX	UPF0352 protein
BM523_09030	ENOG4106V8H	Nucleoid-associated protein
BM523_09060	ENOG4108HRK	Histidine kinase
BM523_09065	ENOG4108VAC	response regulator
BM523_09070	ENOG4105CTQ	phosphohexokinase
BM523_09080	ENOG4105W1Y	Transcriptional regulator
BM523_09095	ENOG4105PGM	cation diffusion facilitator family transporter
BM523_09130	ENOG4105BZU	Histidine kinase
BM523_09140	ENOG4105C72	UPF0176 protein
BM523_09150	ENOG4105C1J	atp-dependent rna helicase
BM523_09160	ENOG4105D6N	CoA-transferase, subunit a
BM523_09165	ENOG4105F04	LysR family Transcriptional regulator
BM523_09180	ENOG4107R11	Transcriptional regulator
BM523_09185	ENOG4105EJQ	L-serine dehydratase
BM523_09195	ENOG4105CRQ	synthase (Component I)
BM523_09205	ENOG4105CGY	Dna recombination protein
BM523_09210	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
BM523_09220	ENOG4105CPP	Dehydrogenase, E1 component
BM523_09230	ENOG4105D6S	protein involved in catabolism of external DNA
BM523_09240	ENOG4105C29	acyl-CoA thioesterase
BM523_09245	ENOG4108Z0R	Transferase
BM523_09250	ENOG4105C5R	Aminotransferase
BM523_09260	ENOG4108ZGC	gaf domain protein
BM523_09270	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
BM523_09275	ENOG4105CN1	protease
BM523_09280	ENOG4105C8J	)-transporter
BM523_09285	ENOG4105DFD	Na H antiporter
BM523_09290	ENOG4105CD8	aminopeptidase N
BM523_09305	ENOG4105D25	secreted protein
BM523_09320	ENOG4105C7I	Dehydrogenase
BM523_09325	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
BM523_09330	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
BM523_09340	ENOG4105C5H	ABC transporter
BM523_09350	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
BM523_09355	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
BM523_09365	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BM523_09370	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BM523_09375	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BM523_09380	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
BM523_09395	ENOG4105DUU	IucA IucC family protein
BM523_09400	ENOG4105CEY	Amp-dependent synthetase and ligase
BM523_09405	ENOG41086VD	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BM523_09410	ENOG4108WBH	protein TIM barrel
BM523_09440	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BM523_09450	ENOG41080IJ	Diacylglycerol kinase
BM523_09455	ENOG41081QV	Universal stress protein
BM523_09465	ENOG4105CBC	glutamate synthase
BM523_09470	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
BM523_09475	ENOG4108UQY	Iron-storage protein
BM523_09490	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
BM523_09505	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
BM523_09530	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
BM523_09535	ENOG4105Q9Y	Universal stress protein
BM523_09540	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
BM523_09545	ENOG4105D78	K07001 NTE family protein
BM523_09570	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
BM523_09575	ENOG4105KHC	sulfurtransferase
BM523_09580	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
BM523_09585	ENOG4106IUH	DTW domain containing protein
BM523_09605	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BM523_09610	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BM523_09615	ENOG4105WH1	Two component transcriptional regulator luxr family
BM523_09620	ENOG4105CHM	Aminotransferase
BM523_09625	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
BM523_09635	ENOG4108MN8	Membrane
BM523_09640	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
BM523_09655	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
BM523_09675	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BM523_09680	ENOG4105WMR	Protein CrcB homolog
BM523_09685	ENOG4105D1H	recombination factor protein RarA
BM523_09695	ENOG4105CNU	cell division protein FtsK
BM523_09700	ENOG4105EW9	transcriptional regulator AsnC family
BM523_09705	ENOG4105DCF	alanine dehydrogenase
BM523_09710	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
BM523_09715	ENOG4105CFV	Tetratricopeptide repeat protein
BM523_09730	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
BM523_09735	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BM523_09740	ENOG4105CAT	Cytidine monophosphate kinase
BM523_09745	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BM523_09750	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
BM523_09755	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BM523_09760	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
BM523_09765	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BM523_09770	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BM523_09775	ENOG4105XPH	Ferredoxin
BM523_09790	ENOG4105BZU	Histidine kinase
BM523_09800	ENOG4105C8V	SAICAR synthetase
BM523_09805	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BM523_09810	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BM523_09820	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BM523_09830	ENOG4105ERG	peptidase m48, ste24p
BM523_09840	ENOG4105K89	arsenate reductase
BM523_09845	ENOG4105CS1	NAD(P)H quinone oxidoreductase
BM523_09855	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
BM523_09865	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BM523_09870	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
BM523_09880	ENOG4107QPN	acyl-Coa dehydrogenase
BM523_09895	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
BM523_09900	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
BM523_09905	ENOG4105DBI	uridine monophosphokinase
BM523_09910	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
BM523_09915	ENOG4105C3Q	Glycosyl transferase, family 2
BM523_09920	ENOG4107QW3	Sucrose phosphorylase
BM523_09925	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BM523_09930	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BM523_09935	ENOG4107QI1	Mate efflux family protein
BM523_09955	ENOG4105C6T	cysteine synthase
BM523_10015	ENOG4105FQP	Beta-lactamase
BM523_10130	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BM523_10140	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BM523_10145	ENOG41060WC	Enoyl-CoA hydratase
BM523_10165	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
BM523_10175	ENOG4105C28	cystathionine
BM523_10190	ENOG4105CGF	Aromatic amino acid aminotransferase
BM523_10205	ENOG4108UPT	UPF0178 protein
BM523_10210	ENOG4105CHR	reductase
BM523_10215	ENOG4105CHR	reductase
BM523_10220	ENOG4105CSU	acyl-Coa dehydrogenase
BM523_10225	ENOG4105FTV	AraC Family Transcriptional Regulator
BM523_10250	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
BM523_10260	ENOG4105C10	Electron transfer flavoprotein
BM523_10265	ENOG4105BZJ	Electron transfer flavoprotein
BM523_10270	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
BM523_10275	ENOG4108YX2	DNA-binding protein
BM523_10280	ENOG4105EV9	Alpha Beta Hydrolase
BM523_10290	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
BM523_10295	ENOG4108NVR	Methyl-accepting chemotaxis
BM523_10300	ENOG41090R7	Ferric uptake
BM523_10315	ENOG4105P4J	Allophanate hydrolase, subunit 1
BM523_10320	ENOG4105E7W	lamb ycsf family protein
BM523_10325	ENOG4105QNR	S1 RNA binding domain protein
BM523_10330	ENOG4108UKZ	OsmC family
BM523_10335	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
BM523_10360	ENOG4105CHM	Aminotransferase
BM523_10365	ENOG4105DK2	UPF0207 protein
BM523_10370	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
BM523_10395	ENOG4105K5B	UPF0225 protein
BM523_10400	ENOG4105BZU	Histidine kinase
BM523_10415	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
BM523_10425	ENOG4105C1G	acyl-Coa dehydrogenase
BM523_10435	ENOG4107ZSV	Receptor
BM523_10455	ENOG4105D4P	Coproporphyrinogen iii oxidase
BM523_10460	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
BM523_10465	ENOG4105E0C	molybdate abc transporter
BM523_10475	ENOG4108ZAF	Molybdopterin
BM523_10480	ENOG4105M00	molybdopterin converting factor, subunit 1
BM523_10490	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
BM523_10495	ENOG4105D06	uba thif-type nad fad binding protein
BM523_10510	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
BM523_10530	ENOG4105EG6	Saccharopine dehydrogenase
BM523_10535	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BM523_10555	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
BM523_10560	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BM523_10570	ENOG4107AQZ	Membrane
BM523_10585	ENOG4107QYX	exodeoxyribonuclease v alpha
BM523_10590	ENOG4107QKA	exodeoxyribonuclease V beta
BM523_10595	ENOG4105DSY	exodeoxyribonuclease V, gamma
BM523_10605	ENOG4108IQE	Amp-dependent synthetase and ligase
BM523_10630	ENOG4105CVI	Transcriptional regulator
BM523_10645	ENOG41082SX	arsR family transcriptional regulator
BM523_10655	ENOG4105DUM	transcriptional regulator, lysR family
BM523_10665	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM523_10710	ENOG4105DK2	UPF0207 protein
BM523_10735	ENOG4105VUT	cytoplasmic protein
BM523_10750	ENOG4105BZG	amino acid carrier protein
BM523_10770	ENOG4105E0X	reductase
BM523_10775	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
BM523_10785	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BM523_10790	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
BM523_10795	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BM523_10800	ENOG4105DSB	aldose 1-epimerase
BM523_10805	ENOG4108UHU	Aldolase
BM523_10810	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BM523_10815	ENOG4105C01	Dihydroxy-acid dehydratase
BM523_10820	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
BM523_10825	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
BM523_10830	ENOG4106KNT	transcriptional regulator
BM523_10835	ENOG4105CA9	Pyruvate kinase
BM523_10840	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BM523_10855	ENOG4105K3G	Periplasmic Protein
BM523_10885	ENOG4105EIG	urea carboxylase-associated protein 1
BM523_10905	ENOG4105CHR	reductase
BM523_10915	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
BM523_10920	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
BM523_10925	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
BM523_10930	ENOG4105ETE	Transcriptional regulator (LacI family
BM523_10935	ENOG4105CTX	dehydratase
BM523_10940	ENOG4105D2H	Uronic isomerase
BM523_10945	ENOG4105DEI	Mannitol dehydrogenase
BM523_10950	ENOG4108UHU	Aldolase
BM523_10955	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
BM523_10970	ENOG4107XII	Glycosyl Hydrolase Family 88
BM523_10980	ENOG4105BZU	Histidine kinase
BM523_10995	ENOG4108K8S	endonuclease I
BM523_11000	ENOG4105C8Q	Methyl-accepting chemotaxis
BM523_11015	ENOG4108W5M	transcriptional regulator
BM523_11020	ENOG4108I6A	alcohol dehydrogenase
BM523_11035	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BM523_11040	ENOG4105BZU	Histidine kinase
BM523_11055	ENOG4105C8P	)-transporter
BM523_11060	ENOG4105DHP	deoxycytidine triphosphate deaminase
BM523_11065	ENOG4105D1F	ATP-binding protein
BM523_11070	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BM523_11080	ENOG4105D1A	Methyltransferase
BM523_11085	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BM523_11090	ENOG4105E9H	Lytic Murein transglycosylase
BM523_11110	ENOG4105C8N	cysteinyl-tRNA synthetase
BM523_11115	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BM523_11120	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
BM523_11130	ENOG4107S78	Band 7 protein
BM523_11145	ENOG4105KVH	Transcriptional regulator
BM523_11160	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
BM523_11170	ENOG4105CIS	alcohol dehydrogenase
BM523_11200	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
BM523_11210	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
BM523_11215	ENOG4105E96	Colicin v production protein
BM523_11220	ENOG4108S3P	Sporulation domain protein
BM523_11225	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BM523_11230	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BM523_11245	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
BM523_11250	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
BM523_11255	ENOG4105MP9	class II Aldolase
BM523_11270	ENOG4108XHQ	(2Fe-2S)-binding domain protein
BM523_11290	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BM523_11305	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
BM523_11340	ENOG4108Z6Z	Transcriptional regulator
BM523_11345	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
BM523_11370	ENOG4105DKW	ABC transporter
BM523_11375	ENOG4105CRW	Short chain fatty acid transporter
BM523_11380	ENOG4105BZU	Histidine kinase
BM523_11405	ENOG4108BPE	-transporting atpase
BM523_11430	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BM523_11455	ENOG4105D8T	Acyltransferase
BM523_11465	ENOG4108UH6	UPF0754 membrane protein
BM523_11490	ENOG4105CUG	Oligopeptidase b
BM523_11495	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
BM523_11500	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
BM523_11505	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
BM523_11510	ENOG4108428	Inherit from COG: -acetyltransferase
BM523_11520	ENOG4108ZZ3	UPF0260 protein
BM523_11525	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
BM523_11535	ENOG4105VNG	YcgL domain-containing protein
BM523_11540	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
BM523_11545	ENOG4105CEY	Amp-dependent synthetase and ligase
BM523_11550	ENOG410832A	alpha/beta hydrolase fold
BM523_11565	ENOG41072GX	Peptidase M22 Glycoprotease
BM523_11570	ENOG4105DVT	helicase
BM523_11620	ENOG4107T8T	UPF0173 metal-dependent hydrolase
BM523_11625	ENOG4105D05	Receptor
BM523_11635	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
BM523_11640	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BM523_11645	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BM523_11650	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BM523_11655	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
BM523_11660	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BM523_11665	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
BM523_11670	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
BM523_11675	ENOG4105S64	Formate nitrite transporter
BM523_11680	ENOG4108NVR	Methyl-accepting chemotaxis
BM523_11710	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BM523_11715	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
BM523_11720	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
BM523_11730	ENOG4105BZU	Histidine kinase
BM523_11800	ENOG4107R08	Integrase
BM523_11815	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BM523_11820	ENOG4107QMP	dna polymerase iii subunits gamma and tau
BM523_11825	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BM523_11835	ENOG4105E18	UPF0276 protein
BM523_11845	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BM523_11885	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
BM523_11905	ENOG4105CXG	d-lactate dehydrogenase
BM523_11910	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BM523_11915	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
BM523_11920	ENOG4105C34	Pseudouridine synthase
BM523_11925	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM523_11935	ENOG4105K6V	RNA polymerase
BM523_11950	ENOG4105EMU	Dehydrogenase
BM523_11965	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
BM523_11970	ENOG4106VK6	Flagellar motor protein
BM523_11975	ENOG4105E14	MotA TolQ exbB proton channel
BM523_11985	ENOG4105CTB	Polyprenyl synthetase
BM523_11990	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BM523_11995	ENOG4108ZAI	phosphatidylglycerophosphatase a
BM523_12000	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
BM523_12005	ENOG4107YIM	Involved in the transcription termination process (By similarity)
BM523_12010	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
BM523_12025	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
BM523_12030	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
BM523_12035	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BM523_12040	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BM523_12045	ENOG4105C5H	ABC transporter
BM523_12055	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
BM523_12065	ENOG4105EAC	phosphoserine phosphatase
BM523_12075	ENOG4105EYA	deoxyribonuclease
BM523_12080	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
BM523_12085	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BM523_12090	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BM523_12095	ENOG4105C3F	Signal peptidase i
BM523_12100	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
BM523_12120	ENOG4105EMN	RNA polymerase sigma factor
BM523_12125	ENOG4108IYU	L-aspartate oxidase
BM523_12140	ENOG4105Y75	tpr repeat protein
BM523_12145	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
BM523_12150	ENOG4108YZY	peptidylprolyl cis-trans isomerase
BM523_12155	ENOG4108YZA	Nitrogen regulatory protein pii
BM523_12160	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
BM523_12220	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
BM523_12225	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
BM523_12230	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BM523_12235	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BM523_12240	ENOG4105DTN	riboflavin biosynthesis protein ribF
BM523_12245	ENOG4105CJR	Integral membrane protein (MviN
BM523_12250	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
BM523_12265	ENOG4105CHR	reductase
BM523_12270	ENOG4105C09	Bile acid
BM523_12275	ENOG4108PTX	LysR family Transcriptional regulator
BM523_12295	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BM523_12300	ENOG4105EIN	peptidylprolyl cis-trans isomerase
BM523_12305	ENOG4105K70	DNA-binding protein
BM523_12310	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
BM523_12315	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BM523_12320	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BM523_12325	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BM523_12355	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BM523_12365	ENOG4108R96	Methyltransferase, YaeB family
BM523_12370	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BM523_12375	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BM523_12380	ENOG4105HDD	phospholipase
BM523_12385	ENOG4105DGU	Histone deacetylase
BM523_12390	ENOG4105C8Q	Methyl-accepting chemotaxis
BM523_12395	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BM523_12400	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BM523_12405	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BM523_12420	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BM523_12425	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BM523_12430	ENOG4105N21	Membrane
BM523_12435	ENOG4105CUT	histidyl-tRNA synthetase
BM523_12440	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BM523_12455	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BM523_12460	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BM523_12465	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
BM523_12475	ENOG4108Z4V	iron-sulfur cluster assembly
BM523_12480	ENOG4105C9B	Cysteine desulfurase
BM523_12485	ENOG4105JRK	feS assembly protein SufD
BM523_12490	ENOG4105C3K	feS assembly ATPase SufC
BM523_12500	ENOG4105C3J	Cysteine desulfurase
BM523_12505	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
BM523_12510	ENOG4105CT3	Monooxygenase
BM523_12515	ENOG4105D7W	serine acetyltransferase
BM523_12520	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
BM523_12540	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BM523_12545	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BM523_12550	ENOG4105VIE	preprotein translocase, subunit YajC
BM523_12555	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BM523_12560	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
BM523_12575	ENOG4108P9J	Phage shock protein A
BM523_12600	ENOG4106032	Glutathionylspermidine synthase
BM523_12615	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BM523_12630	ENOG4105CSV	Glutaminase
BM523_12635	ENOG4105G6Z	alkaline phosphatase
BM523_12645	ENOG4107RET	Isocitrate lyase
BM523_12670	ENOG4105C0H	protease
BM523_12705	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
BM523_12725	ENOG4105CPK	Glycosyl transferase (Group 1
BM523_12740	ENOG4105CAQ	asparagine synthetase
BM523_12745	ENOG4105EXC	Acyl-transferase
BM523_12750	ENOG4108PQP	glycosyl transferase group 1
BM523_12820	ENOG4105D3Q	Sugar transferase
BM523_12835	ENOG4108QV3	biosynthesis protein
BM523_12850	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
BM523_12870	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
BM523_12880	ENOG4105D1S	lipid A biosynthesis
BM523_12895	ENOG4107QPN	acyl-Coa dehydrogenase
BM523_12910	ENOG4105BZU	Histidine kinase
BM523_12915	ENOG4107104	thymidine kinase
BM523_12930	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BM523_12960	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
BM523_12965	ENOG4108RWN	rrna methyltransferase
BM523_12970	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BM523_12985	ENOG4105C26	Dehydrogenase
BM523_12990	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
BM523_13005	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
BM523_13010	ENOG4108Z4X	TRANSCRIPTIONal
BM523_13040	ENOG4105CSU	acyl-Coa dehydrogenase
BM523_13060	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
BM523_13065	ENOG4105E0F	Histidine kinase
BM523_13075	ENOG4105NA0	Transcriptional regulator
BM523_13080	ENOG410822N	TonB family
BM523_13095	ENOG4107XDR	Lactoylglutathione lyase
BM523_13110	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
BM523_13115	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
BM523_13120	ENOG4105C7W	Xanthine dehydrogenase
BM523_13140	ENOG4105CHR	reductase
BM523_13145	ENOG4105EMU	Dehydrogenase
BM523_13150	ENOG4107RKG	DJ-1/PfpI family
BM523_13155	ENOG4107U9T	Pfam:Ribonuclease_BN
BM523_13170	ENOG4108VWS	Yaeq family
BM523_13200	ENOG4105S8Q	sugar efflux transporter
BM523_13220	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BM523_13240	ENOG4105BZU	Histidine kinase
BM523_13245	ENOG4105BZU	Histidine kinase
BM523_13260	ENOG4105BZU	Histidine kinase
BM523_13310	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BM523_13315	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BM523_13320	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BM523_13325	ENOG4105CE4	GlcNAc 6-P deacetylase
BM523_13330	ENOG4105RD7	BadF BadG BcrA BcrD
BM523_13340	ENOG4105DAA	L-lactate
BM523_13365	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
BM523_13370	ENOG4105D0A	hydroxylase
BM523_13375	ENOG4107RAQ	aminopeptidase
BM523_13390	ENOG4108RVA	ribokinase
BM523_13405	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
BM523_13410	ENOG4105E66	phosphoriboisomerase A
BM523_13415	ENOG4108JQ1	Dehydrogenase
BM523_13435	ENOG4105XZD	Fe-S protein
BM523_13470	ENOG4107QN2	dihydrolipoyl dehydrogenase
BM523_13475	ENOG4107QSN	dihydrolipoamide acetyltransferase
BM523_13480	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
BM523_13485	ENOG41073TP	transcriptional regulator
BM523_13495	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
BM523_13500	ENOG4108WIW	Aspartyl protease
BM523_13505	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
BM523_13510	ENOG4108ZUW	Major pilin subunit
BM523_13515	ENOG4105D7Q	type ii secretion system
BM523_13520	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
BM523_13530	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
BM523_13535	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
BM523_13540	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
BM523_13550	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BM523_13555	ENOG4105DR5	peptidase
BM523_13560	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BM523_13565	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BM523_13570	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
BM523_13575	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
BM523_13580	ENOG4105CPF	Cell wall formation (By similarity)
BM523_13585	ENOG4105DFU	Cell wall formation (By similarity)
BM523_13590	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BM523_13595	ENOG4105CNI	cell division protein FtsW
BM523_13600	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BM523_13605	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BM523_13610	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
BM523_13615	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
BM523_13620	ENOG4105CJN	penicillin-binding protein
BM523_13625	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
BM523_13630	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BM523_13635	ENOG4108V6E	Cell division protein mraZ
BM523_13660	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
BM523_13680	ENOG4105EHV	domain protein
BM523_13695	ENOG4105BZU	Histidine kinase
BM523_13705	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM523_13710	ENOG4105BZU	Histidine kinase
BM523_13720	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BM523_13725	ENOG4105DPW	Major facilitator superfamily MFS_1
BM523_13755	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
BM523_13760	ENOG4105D7Z	glutathione synthase
BM523_13765	ENOG4108UJU	UPF0301 protein
BM523_13770	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BM523_13780	ENOG4105CZX	twitching motility protein
BM523_13785	ENOG4105CZX	twitching motility protein
BM523_13790	ENOG4105DFA	alanine racemase domain protein
BM523_13795	ENOG4105II7	pyrroline-5-carboxylate reductase
BM523_13800	ENOG4108VIA	integral membrane protein
BM523_13810	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BM523_13825	ENOG4108SHQ	Glutathione S-transferase
BM523_13830	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BM523_13835	ENOG4108Z9K	Osmotically inducible protein
BM523_13840	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BM523_13855	ENOG4108UMN	azlc family
BM523_13865	ENOG4105F27	Major Facilitator
BM523_13870	ENOG4105VFU	Rna-binding protein
BM523_13875	ENOG4105D1Q	UPF0246 protein
BM523_13885	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
BM523_13890	ENOG4107QP8	phosphohexose isomerase
BM523_13895	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BM523_13900	ENOG4105D98	threonine synthase
BM523_13905	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
BM523_13920	ENOG4105CC0	LysR family Transcriptional regulator
BM523_13935	ENOG41082YX	Transcriptional regulator, arsr family
BM523_13945	ENOG4105CAU	Arsenical resistance protein, ArsH
BM523_13950	ENOG4105D6J	arsenicaL-resistance protein
BM523_13955	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BM523_13960	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
BM523_13970	ENOG4105BZU	Histidine kinase
BM523_13985	ENOG4105K6H	D-cysteine desulfhydrase
BM523_14015	ENOG4105E3Q	saccharopine dehydrogenase
BM523_14030	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
BM523_14035	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
BM523_14040	ENOG41082RQ	UPF0102 protein
BM523_14050	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
BM523_14055	ENOG4105W4M	Transport-associated protein
BM523_14075	ENOG4105BZU	Histidine kinase
BM523_14105	ENOG4105CR4	methylisocitrate lyase
BM523_14110	ENOG4105BZN	citrate synthase
BM523_14115	ENOG4108I0Z	Aconitate hydratase
BM523_14120	ENOG4105C7F	AcnD-accessory protein PrpF
BM523_14125	ENOG4105BZU	Histidine kinase
BM523_14145	ENOG4105BZU	Histidine kinase
BM523_14150	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
BM523_14155	ENOG4105CBC	glutamate synthase
BM523_14160	ENOG4105BZ8	glutamate synthase
BM523_14180	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BM523_14185	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
BM523_14190	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
BM523_14195	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
BM523_14210	ENOG4105CJP	fad dependent oxidoreductase
BM523_14215	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
BM523_14220	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BM523_14225	ENOG4108K5P	(LipO)protein
BM523_14230	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
BM523_14235	ENOG4105EDR	glucose galactose transporter
BM523_14265	ENOG4108U78	Glutathione S-transferase
BM523_14270	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
BM523_14280	ENOG4105CSR	polyphosphate kinase 2
BM523_14285	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
BM523_14290	ENOG4107QMS	site-determining protein
BM523_14295	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
BM523_14300	ENOG4105C9Q	fumarate hydratase class II
BM523_14340	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
BM523_14345	ENOG4105CHM	Aminotransferase
BM523_14355	ENOG4105CI3	gtp-binding protein typa
BM523_14360	ENOG4105C5F	glutamine synthetase
BM523_14370	ENOG4105CUX	Signal transduction histidine kinase
BM523_14375	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM523_14380	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BM523_14385	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
BM523_14390	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
BM523_14400	ENOG4105BZU	Histidine kinase
BM523_14420	ENOG4105BZU	Histidine kinase
BM523_14425	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BM523_14430	ENOG4105MYG	DNA polymerase iii, chi subunit
BM523_14435	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BM523_14440	ENOG4108M8S	permease YjgP YjgQ family protein
BM523_14445	ENOG4108K5H	permease YjgP YjgQ family protein
BM523_14460	ENOG4105K6V	RNA polymerase
BM523_14520	ENOG4105E2V	Glycosyltransferase 36
BM523_14530	ENOG410620I	Diguanylate cyclase
BM523_14565	ENOG4105BZU	Histidine kinase
BM523_14585	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
BM523_14590	ENOG4105EHG	Permease protein
BM523_14595	ENOG4107R4I	Periplasmic binding protein
BM523_14605	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BM523_14615	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
BM523_14620	ENOG4105EMK	carboxylate amino acid amine transporter
BM523_14640	ENOG4107RF2	cellulose-binding family II protein
BM523_14650	ENOG4105CY0	Metallo-Beta-Lactamase
BM523_14660	ENOG4105DC7	peptidase M24
BM523_14665	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
BM523_14670	ENOG4105BZU	Histidine kinase
BM523_14675	ENOG4108N2Y	auxin Efflux
BM523_14680	ENOG4105EY3	heparinase II III family protein
BM523_14685	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
BM523_14690	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BM523_14695	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
BM523_14715	ENOG41088PD	hydrolase
BM523_14725	ENOG4105DZG	Dehydrogenase
BM523_14745	ENOG4105CJ1	ABC, transporter
BM523_14755	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BM523_14760	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
BM523_14770	ENOG4105WF7	pyrroloquinoline quinone biosynthesis protein d
BM523_14775	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
BM523_14805	ENOG4105BZU	Histidine kinase
BM523_14825	ENOG4105WH1	Two component transcriptional regulator luxr family
BM523_14830	ENOG4105BZU	Histidine kinase
BM523_14835	ENOG4105JQN	Transcriptional regulator
BM523_14840	ENOG4105C26	Dehydrogenase
BM523_14845	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BM523_14860	ENOG4105C94	Transporter
BM523_14865	ENOG4105CXG	d-lactate dehydrogenase
BM523_14870	ENOG41086KC	Transcriptional regulator
BM523_14875	ENOG4105P8Q	Curli production assembly transport component CsgG
BM523_14905	ENOG4105WH1	Two component transcriptional regulator luxr family
BM523_14930	ENOG4105C1J	atp-dependent rna helicase
BM523_14945	ENOG4108UHU	Aldolase
BM523_14950	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
BM523_14965	ENOG4105EGS	Mechanosensitive ion channel
BM523_14975	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
BM523_15005	ENOG4105HF0	Membrane
BM523_15010	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BM523_15025	ENOG4105BZU	Histidine kinase
BM523_15035	ENOG4105CQ2	DNA polymerase
BM523_15045	ENOG4105CEY	Amp-dependent synthetase and ligase
BM523_15085	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
BM523_15090	ENOG4105EJ2	Transcriptional regulator
BM523_15100	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
BM523_15110	ENOG4108RG0	uracil-dna glycosylase
BM523_15115	ENOG4105BZU	Histidine kinase
BM523_15125	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
BM523_15130	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
BM523_15155	ENOG4105FM1	phage shock protein C
BM523_15160	ENOG41087YS	Phage shock protein A
BM523_15170	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BM523_15190	ENOG4105EDQ	levansucrase EC 2.4.1.10
BM523_15195	ENOG4108HKT	sucrose-6-phosphate hydrolase
BM523_15220	ENOG4105CPK	Glycosyl transferase (Group 1
BM523_15250	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
BM523_15255	ENOG4105BZU	Histidine kinase
BM523_15260	ENOG4105C4W	S-formylglutathione hydrolase
BM523_15265	ENOG4106HNH	Acyl-transferase
BM523_15270	ENOG4106HNH	Acyl-transferase
BM523_15275	ENOG4105CUY	Mechanosensitive ion channel
BM523_15290	ENOG4108535	NAD dependent epimerase/dehydratase family
BM523_15295	ENOG4105C8J	)-transporter
BM523_15310	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BM523_15325	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
BM523_15335	ENOG4109015	Biopolymer transport protein exbD tolR
BM523_15345	ENOG4105EJG	cellulose synthase
BM523_15350	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
BM523_15360	ENOG4107QZ7	Cellulose synthase catalytic subunit
BM523_15375	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
BM523_15380	ENOG4105K4T	epimerase
BM523_15390	ENOG4105KWG	Pfam:DUF1696
BM523_15395	ENOG4105BZU	Histidine kinase
BM523_15405	ENOG4105EFZ	amidohydrolase
BM523_15415	ENOG4105C5X	domain protein
BM523_15425	ENOG4108WAV	Transcriptional regulator
BM523_15430	ENOG4105E7A	Glutamine amidotransferase
BM523_15440	ENOG4108Z12	YiaAB two helix domain-containing protein
BM523_15460	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
BM523_15470	ENOG4105C26	Dehydrogenase
BM523_15475	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
BM523_15480	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
BM523_15485	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
BM523_15495	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
BM523_15500	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
BM523_15505	ENOG4108R86	Transcriptional regulator
BM523_15520	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
BM523_15530	ENOG4105E53	ec 3.2.1.28
BM523_15535	ENOG4105C6Z	Gluconate
BM523_15540	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BM523_15545	ENOG4105K2J	Transcriptional regulator
BM523_15550	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BM523_15560	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BM523_15580	ENOG4105CJ2	(LipO)protein
BM523_15585	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
BM523_15590	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BM523_15595	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BM523_15600	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BM523_15605	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BM523_15610	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BM523_15615	ENOG4105RKW	reductase (By
BM523_15620	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BM523_15625	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
BM523_15640	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BM523_15645	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
BM523_15670	ENOG4105DBI	uridine monophosphokinase
BM523_15675	ENOG4105D9N	nucleoside
BM523_15695	ENOG4105BZU	Histidine kinase
BM523_15700	ENOG4107S1V	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
BM523_15710	ENOG4107QN1	sodium solute
BM523_15720	ENOG4105BZU	Histidine kinase
BM523_15730	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
BM523_15740	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
BM523_15755	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BM523_15770	ENOG4105CPC	Aldo Keto reductase
BM523_15795	ENOG4105D9P	serine threonine protein kinase
BM523_15845	ENOG4105CH6	catalase
BM523_15880	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
BM523_15885	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
BM523_15890	ENOG4105D4A	Cell wall formation (By similarity)
BM523_15895	ENOG4107SDU	Methyl-accepting chemotaxis
BM523_15940	ENOG4108JJA	ABC, transporter
BM523_15945	ENOG41063Z6	transcriptional regulator, lysR family
BM523_15985	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
BM523_15990	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
BM523_15995	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
BM523_16010	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BM523_16050	ENOG4105K64	Glycosyl transferase, family 2
BM523_16070	ENOG4105F0R	Cytidylyltransferase
BM523_16075	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BM523_16080	ENOG4105C5E	polysaccharide biosynthesis protein
BM523_16100	ENOG4108ZT0	50S ribosomal protein l17
BM523_16105	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BM523_16110	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BM523_16115	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BM523_16120	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BM523_16125	ENOG41067V7	50S ribosomal protein L36
BM523_16130	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BM523_16135	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BM523_16140	ENOG4105VPB	50S ribosomal protein L30
BM523_16145	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BM523_16150	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BM523_16155	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BM523_16160	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BM523_16165	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BM523_16170	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BM523_16175	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BM523_16180	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BM523_16185	ENOG4105BZU	Histidine kinase
BM523_16195	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BM523_16200	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BM523_16205	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BM523_16240	ENOG4108UV7	flagellar protein motX
BM523_16250	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
BM523_16255	ENOG4107QK7	reductase
BM523_16265	ENOG4107VAM	peptidase, m28
BM523_16275	ENOG4105BZU	Histidine kinase
BM523_16295	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BM523_16300	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BM523_16305	ENOG4108XM1	transcriptional regulator AsnC family
BM523_16315	ENOG4105VEQ	Cold shock protein
BM523_16320	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
BM523_16340	ENOG4105DGW	oligopeptidase A
BM523_16345	ENOG4107YTP	response regulator receiver protein
BM523_16355	ENOG4105BZU	Histidine kinase
BM523_16360	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM523_16365	ENOG4105DC8	reductase
BM523_16370	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
BM523_16375	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BM523_16420	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
BM523_16425	ENOG4108JJA	ABC, transporter
BM523_16430	ENOG4105WH1	Two component transcriptional regulator luxr family
BM523_16455	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
BM523_16460	ENOG4108HKT	sucrose-6-phosphate hydrolase
BM523_16475	ENOG4105C27	TonB-dependent Receptor Plug
BM523_16480	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
BM523_16485	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
BM523_16490	ENOG4105VEQ	Cold shock protein
BM523_16495	ENOG41063M6	Cell Division Protein
BM523_16500	ENOG4105C25	Primosomal protein n'
BM523_16505	ENOG4105VFB	Binds the 23S rRNA (By similarity)
BM523_16515	ENOG4105C6K	Malic enzyme
BM523_16520	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
BM523_16525	ENOG4105SYT	Methylenetetrahydrofolate reductase
BM523_16530	ENOG4107S2Z	UPF0761 membrane protein
BM523_16550	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
BM523_16555	ENOG4105SUU	thioesterase domain
BM523_16560	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM523_16565	ENOG4105D58	Diguanylate phosphodiesterase
BM523_16570	ENOG4105D58	Diguanylate phosphodiesterase
BM523_16575	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
BM523_16580	ENOG4105CAK	Cell division ATP-binding protein ftsE
BM523_16585	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BM523_16590	ENOG4106H78	methyltransferase
BM523_16600	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
BM523_16615	ENOG4105PW4	Sugar fermentation stimulation protein homolog
BM523_16620	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BM523_16625	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
BM523_16630	ENOG4105DJ0	Poly(A) Polymerase
BM523_16635	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BM523_16640	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
BM523_16645	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
BM523_16650	ENOG4105DY8	decarboxylase
BM523_16665	ENOG4105E3A	(ABC) transporter
BM523_16670	ENOG4105DA5	(ABC) transporter
BM523_16675	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
BM523_16680	ENOG4105EB3	Histidine kinase
BM523_16685	ENOG4108ESX	Receptor
BM523_16690	ENOG4107E2E	PKHD-type hydroxylase
BM523_16720	ENOG4105D22	carbon starvation protein
BM523_16745	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BM523_16750	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BM523_16755	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BM523_16760	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BM523_16765	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BM523_16770	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BM523_16775	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BM523_16780	ENOG4108VZM	50s ribosomal protein L10
BM523_16785	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BM523_16790	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BM523_16810	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BM523_16815	ENOG4105PM1	preprotein translocase subunit SecE
BM523_16825	ENOG4105BZ1	(ABC) transporter
BM523_16830	ENOG4105JSC	dimethylmenaquinone methyltransferase
BM523_16835	ENOG4105C9K	Endothelin-converting enzyme 1
BM523_16845	ENOG4105C1J	atp-dependent rna helicase
BM523_16850	ENOG4105EKE	dihydroorotase
BM523_16855	ENOG4105QNF	Outer membrane lipoprotein
BM523_16860	ENOG4107RGM	aldo keto reductase
BM523_16865	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
BM523_16875	ENOG4105DP8	Major facilitator superfamily MFS_1
BM523_16880	ENOG4107QW3	Sucrose phosphorylase
BM523_16890	ENOG4105EUJ	GTP cyclohydrolase i
BM523_16895	ENOG410642E	Short chain dehydrogenase
BM523_16900	ENOG4105DWY	Agmatine deiminase
BM523_16915	ENOG4107QRT	dEAD DEAH box helicase
BM523_16925	ENOG4107T0X	DNA ligase
BM523_16930	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BM523_16935	ENOG4105D7K	pfkb domain protein
BM523_16950	ENOG4105CYM	Glutathione S-transferase
BM523_16965	ENOG4107IFA	Lipase (EC 3.1.1.3)
BM523_16970	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
BM523_16995	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
BM523_17000	ENOG4105CFC	Transporter
BM523_17005	ENOG4105EPW	hflc protein
BM523_17010	ENOG4107QJR	hflk protein
BM523_17015	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BM523_17020	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
BM523_17025	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BM523_17030	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BM523_17035	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BM523_17040	ENOG4105K8N	protein family UPF0079, ATPase
BM523_17045	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BM523_17050	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
BM523_17060	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
BM523_17070	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
BM523_17075	ENOG4105MYN	Zinc uptake regulation protein
BM523_17085	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
BM523_17090	ENOG4105CDV	Ompa motb domain protein
BM523_17095	ENOG4105CDU	Replicative dna helicase
BM523_17120	ENOG4108RPX	mosc domain containing protein
BM523_17140	ENOG410804D	Sensor Signal Transduction Histidine Kinase
BM523_17165	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
BM523_17170	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BM523_17175	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
BM523_17180	ENOG4105BZU	Histidine kinase
BM523_17190	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BM523_17200	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
BM523_17205	ENOG4105BZU	Histidine kinase
BM523_17210	ENOG4105C8Q	Methyl-accepting chemotaxis
BM523_17230	ENOG4106IBS	oxygenase
BM523_17240	ENOG4105FDP	GntR family transcriptional regulator
BM523_17250	ENOG4105CJQ	hydrolase, family 31
BM523_17255	ENOG4107RUZ	Sss sodium solute transporter superfamily
BM523_17260	ENOG4107ZSV	Receptor
BM523_17265	ENOG4105PGM	cation diffusion facilitator family transporter
BM523_17280	ENOG4105DFD	Na H antiporter
BM523_17300	ENOG41060NJ	transcriptional regulator
BM523_17305	ENOG4107QNK	)-transporter
BM523_17310	ENOG4108JJ8	(ABC) transporter
BM523_17315	ENOG4108JJ9	ABC, transporter
BM523_17325	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BM523_17330	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BM523_17365	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
BM523_17375	ENOG4105D05	Receptor
BM523_17390	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
BM523_17405	ENOG4105Q26	Siderophore-interacting protein
BM523_17410	ENOG4105VDW	Csbd family
BM523_17425	ENOG4105EMN	RNA polymerase sigma factor
BM523_17430	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BM523_17450	ENOG4108YZN	class I peptide chain release factor
BM523_17455	ENOG4107TTQ	Alpha beta hydrolase fold
BM523_17475	ENOG4105DS1	cytochrome b561
BM523_17485	ENOG4105CEP	NADH dehydrogenase
BM523_17500	ENOG4105CR8	Transcriptional regulator
BM523_17505	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
BM523_17510	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
BM523_17520	ENOG4105BZU	Histidine kinase
BM523_17530	ENOG4105DEN	Luciferase family
BM523_17535	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BM523_17540	ENOG4105E98	transcriptional regulator DeoR family
BM523_17545	ENOG4105D9R	oxidoreductase
BM523_17550	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BM523_17560	ENOG4108Q5Y	Membrane
BM523_17565	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BM523_17570	ENOG4105D03	DNA-3-methyladenine glycosylase II
BM523_17575	ENOG41066YJ	Beta-lactamase
BM523_17580	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
BM523_17590	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BM523_17595	ENOG4105W8H	transhydrogenase (subunit alpha
BM523_17600	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BM523_17650	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
BM523_17680	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BM523_17695	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BM523_17700	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BM523_17705	ENOG4105FS0	cytoplasmic membrane protein
BM523_17710	ENOG4105VF7	tolerance protein
BM523_17715	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
BM523_17720	ENOG4105DR5	peptidase
BM523_17725	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BM523_17730	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
BM523_17735	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BM523_17775	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BM523_17785	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BM523_17790	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BM523_17795	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
BM523_17800	ENOG4105DC1	bifunctional purine biosynthesis protein purh
BM523_17810	ENOG4105C12	Phosphoribosylglycinamide synthetase
BM523_17830	ENOG4105EYW	Ion transport protein
BM523_17835	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
BM523_17845	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BM523_17850	ENOG4105E0F	Histidine kinase
BM523_17860	ENOG4105CJQ	hydrolase, family 31
BM523_17935	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
BM523_17940	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BM523_17945	ENOG4105VEJ	Heat shock protein
BM523_17950	ENOG4108XKW	General secretion pathway protein C
BM523_17960	ENOG4107QHF	type ii secretion system protein e
BM523_17965	ENOG4105D7Q	type ii secretion system
BM523_17970	ENOG4108VAU	general secretion pathway protein G
BM523_17975	ENOG4105VWV	general secretion pathway protein h
BM523_18015	ENOG4105C26	Dehydrogenase
BM523_18025	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
BM523_18030	ENOG4107RK2	ADP-ribose diphosphatase NudE
BM523_18045	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
BM523_18050	ENOG4105DJ9	glucan biosynthesis protein
BM523_18060	ENOG4105YP7	UPF0270 protein
BM523_18065	ENOG4105DNZ	Alpha Beta Hydrolase
BM523_18075	ENOG4105C5H	ABC transporter
BM523_18100	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BM523_18110	ENOG4108RRZ	Transcription elongation factor GreB
BM523_18115	ENOG4105BZM	domain protein
BM523_18135	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
BM523_18140	ENOG4105MJ2	Competence protein
BM523_18150	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
BM523_18175	ENOG4107R73	Mate efflux family protein
BM523_18180	ENOG4107BJW	polysaccharide deacetylase
BM523_18190	ENOG4108ZX6	Electron transport protein SCO1 SenC
BM523_18195	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
BM523_18200	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
BM523_18220	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
BM523_18225	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
BM523_18230	ENOG4105BZ9	Cytochrome C oxidase, subunit I
BM523_18240	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BM523_18245	ENOG4105E55	glycerol-3-phosphate acyltransferase
BM523_18250	ENOG4105C7B	Threonine dehydratase
BM523_18255	ENOG4105C01	Dihydroxy-acid dehydratase
BM523_18260	ENOG4105EN6	Membrane
BM523_18265	ENOG4105C0P	Mg chelatase subunit ChlI
BM523_18270	ENOG4105EMY	transcriptional regulator
BM523_18275	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
BM523_18280	ENOG4105C2C	drug resistance transporter, Bcr CflA
BM523_18285	ENOG4105V1F	Fermentation respiration switch protein
BM523_18290	ENOG4105CFU	surface antigen
BM523_18295	ENOG4105MA0	exported protein
BM523_18320	ENOG4105C5I	Dehydrogenase
BM523_18330	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
BM523_18375	ENOG4105CI2	imidazolone-5-propionate hydrolase
BM523_18400	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
BM523_18405	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BM523_18410	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
BM523_18415	ENOG4105DSJ	YicC domain protein
BM523_18420	ENOG4105QV4	Tryptophan halogenase
BM523_18440	ENOG4105CT4	transporter
BM523_18445	ENOG41060NJ	transcriptional regulator
BM523_18455	ENOG4105CDV	Ompa motb domain protein
BM523_18460	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BM523_18475	ENOG4108K3A	Glutathione S-transferase
BM523_18485	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BM523_18490	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BM523_18495	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BM523_18500	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BM523_18505	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BM523_18510	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BM523_18515	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BM523_18520	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
BM523_18530	ENOG4105FA0	parb-like partition protein
BM523_18535	ENOG4107QJE	Chromosome Partitioning Protein
BM523_18540	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BM523_18545	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BM523_18560	ENOG4105QTB	Flavodoxin
BM523_18565	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BM523_18570	ENOG4108VPT	UPF0234 protein
BM523_18575	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BM523_18580	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)