locus-tag	class	description
BM525_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BM525_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BM525_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BM525_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BM525_00040	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
BM525_00045	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
BM525_00050	ENOG4108R3E	Dna-3-methyladenine glycosylase i
BM525_00060	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
BM525_00070	ENOG4106RE7	Cytochrome
BM525_00075	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BM525_00080	ENOG4105C2M	dna polymerase I
BM525_00085	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
BM525_00090	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
BM525_00095	ENOG4105C1A	potassium transporter peripheral membrane
BM525_00100	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
BM525_00105	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BM525_00110	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BM525_00120	ENOG4105C79	DNA protecting protein DprA
BM525_00125	ENOG4108RPN	Protein smg homolog
BM525_00135	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BM525_00140	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
BM525_00145	ENOG4105EIF	outer membrane protein W
BM525_00155	ENOG4105E2X	shikimate dehydrogenase
BM525_00160	ENOG4108Z0R	Transferase
BM525_00200	ENOG4105C0B	DNA polymerase III (alpha subunit)
BM525_00230	ENOG4105IIU	Aminopeptidase
BM525_00240	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
BM525_00245	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
BM525_00250	ENOG4105W5Q	DNA repair protein (RadC
BM525_00270	ENOG4105E3R	(LipO)protein
BM525_00275	ENOG4105KDC	50s ribosomal protein l28
BM525_00280	ENOG4105W0E	50S ribosomal protein L33
BM525_00290	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BM525_00295	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BM525_00300	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
BM525_00305	ENOG4105DKP	glycosyl transferase, family 9
BM525_00320	ENOG4105BZU	Histidine kinase
BM525_00325	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BM525_00330	ENOG4105CPQ	Dehydrogenase
BM525_00335	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
BM525_00350	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
BM525_00355	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
BM525_00370	ENOG4105W0Z	cytoplasmic protein
BM525_00375	ENOG4105C4R	Atp-dependent dna helicase
BM525_00380	ENOG4105BZU	Histidine kinase
BM525_00385	ENOG4105MPD	Cytochrome
BM525_00405	ENOG4105DFD	Na H antiporter
BM525_00425	ENOG4108VCT	Sulfite exporter TauE/SafE
BM525_00440	ENOG4105UGU	tonB-dependent Receptor
BM525_00455	ENOG4108JJ8	(ABC) transporter
BM525_00460	ENOG4108JJ9	ABC, transporter
BM525_00470	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BM525_00475	ENOG4105VFE	sira family
BM525_00485	ENOG4105D3R	alkyl hydroperoxide reductase
BM525_00490	ENOG4105C94	Transporter
BM525_00515	ENOG4105DVF	Cytosine-specific methyltransferase
BM525_00520	ENOG41090BB	DNA mismatch endonuclease (vsr)
BM525_00550	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BM525_00560	ENOG4105D0S	secretion protein (HlyD
BM525_00565	ENOG4105CJ1	ABC, transporter
BM525_00570	ENOG4105CMI	transporter
BM525_00580	ENOG4107RNH	Outer membrane receptor FepA
BM525_00590	ENOG4105C1G	acyl-Coa dehydrogenase
BM525_00595	ENOG4105DQS	Transcriptional regulator
BM525_00605	ENOG4105CM6	amino acid regulated cytosolic protein
BM525_00620	ENOG4105D41	biosynthesis protein thiH
BM525_00625	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BM525_00635	ENOG4105D06	uba thif-type nad fad binding protein
BM525_00640	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
BM525_00645	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
BM525_00650	ENOG410601J	HemY protein
BM525_00655	ENOG4105ECF	c-methyltransferase
BM525_00660	ENOG41076E6	Uroporphyrinogen-III Synthase
BM525_00665	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
BM525_00670	ENOG4105BZU	Histidine kinase
BM525_00680	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BM525_00685	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BM525_00690	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BM525_00695	ENOG4105KME	endoribonuclease L-psp
BM525_00700	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
BM525_00705	ENOG4105CB5	ATP-dependent DNA helicase recG
BM525_00710	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
BM525_00730	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
BM525_00735	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BM525_00745	ENOG4105CBX	hi0933 family
BM525_00755	ENOG4105BZU	Histidine kinase
BM525_00760	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
BM525_00770	ENOG4105KPY	Small multidrug resistance protein
BM525_00785	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BM525_00790	ENOG4105BZS	acriflavin resistance protein
BM525_00800	ENOG4105CYC	Transferase
BM525_00820	ENOG4105C8Q	Methyl-accepting chemotaxis
BM525_00830	ENOG4108NST	exported protein
BM525_00835	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
BM525_00840	ENOG4105BZU	Histidine kinase
BM525_00855	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BM525_00860	ENOG4105CJW	magnesium transporter
BM525_00865	ENOG4105FR1	rard protein
BM525_00870	ENOG4105BZU	Histidine kinase
BM525_00875	ENOG4105C4R	Atp-dependent dna helicase
BM525_00880	ENOG4105D7W	serine acetyltransferase
BM525_00885	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
BM525_00890	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BM525_00900	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
BM525_00905	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
BM525_00925	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
BM525_00935	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
BM525_00940	ENOG4105DFU	Cell wall formation (By similarity)
BM525_00945	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BM525_00950	ENOG4105F0N	pyrophosphate phospho-hydrolase
BM525_00985	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BM525_00990	ENOG4107RDB	Major Facilitator
BM525_00995	ENOG4107VXZ	Hydrolase
BM525_01020	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
BM525_01025	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
BM525_01035	ENOG4107XMK	single-stranded DNA-binding protein
BM525_01060	ENOG4107RUZ	Sss sodium solute transporter superfamily
BM525_01080	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BM525_01085	ENOG4105E98	transcriptional regulator DeoR family
BM525_01090	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
BM525_01140	ENOG4107QHF	type ii secretion system protein e
BM525_01145	ENOG4105D7Q	type ii secretion system
BM525_01190	ENOG4105DFF	Rod shape-determining protein mreb
BM525_01195	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
BM525_01200	ENOG4105VQ7	Rod shape-determining protein MreD
BM525_01205	ENOG4108Z03	MAF-like protein
BM525_01210	ENOG4105C03	ribonuclease
BM525_01225	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
BM525_01230	ENOG4105N42	UPF0307 protein
BM525_01235	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
BM525_01245	ENOG4105CNT	hydrolase family 2
BM525_01250	ENOG41065U4	response regulator
BM525_01255	ENOG4105BZU	Histidine kinase
BM525_01260	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
BM525_01265	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
BM525_01270	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BM525_01275	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
BM525_01280	ENOG4105CEN	a g-specific adenine glycosylase
BM525_01285	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
BM525_01320	ENOG4105C8Q	Methyl-accepting chemotaxis
BM525_01325	ENOG4108VYJ	response regulator receiver protein
BM525_01330	ENOG4105CBS	Chea signal transduction histidine kinase
BM525_01335	ENOG4108V3W	Chemotaxis protein, CheW
BM525_01340	ENOG4107SDU	Methyl-accepting chemotaxis
BM525_01345	ENOG4105BZU	Histidine kinase
BM525_01350	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
BM525_01360	ENOG4105C8Q	Methyl-accepting chemotaxis
BM525_01365	ENOG4108VYJ	response regulator receiver protein
BM525_01370	ENOG4105CBS	Chea signal transduction histidine kinase
BM525_01375	ENOG4108V3W	Chemotaxis protein, CheW
BM525_01380	ENOG4107SDU	Methyl-accepting chemotaxis
BM525_01385	ENOG4107SDU	Methyl-accepting chemotaxis
BM525_01390	ENOG4105BZU	Histidine kinase
BM525_01395	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
BM525_01445	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BM525_01465	ENOG4105ETE	Transcriptional regulator (LacI family
BM525_01480	ENOG4105EAA	nucleoside
BM525_01505	ENOG4105C0A	alcohol dehydrogenase
BM525_01530	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BM525_01535	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BM525_01545	ENOG4107QM5	aconitate hydratase
BM525_01555	ENOG4107QHF	type ii secretion system protein e
BM525_01565	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BM525_01570	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BM525_01575	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BM525_01580	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BM525_01585	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BM525_01590	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BM525_01595	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BM525_01600	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BM525_01605	ENOG41083MP	50s ribosomal protein l29
BM525_01610	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BM525_01615	ENOG4107RJ7	Glycosyl transferase (Group 1
BM525_01625	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
BM525_01645	ENOG41069D7	Methyl-accepting chemotaxis
BM525_01650	ENOG4105DGW	oligopeptidase A
BM525_01670	ENOG4105CQ7	ATP-dependent helicase
BM525_01675	ENOG4105CVE	Lytic murein transglycosylase
BM525_01680	ENOG4105BZ4	penicillin-binding protein
BM525_01690	ENOG4105CKW	Inner membrane protein yedI
BM525_01700	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
BM525_01710	ENOG4108YZA	Nitrogen regulatory protein pii
BM525_01720	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BM525_01725	ENOG4105EZR	dyp-type peroxidase family protein
BM525_01735	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BM525_01740	ENOG4105CXT	aspartate transcarbamylase
BM525_01765	ENOG4105BZU	Histidine kinase
BM525_01770	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BM525_01780	ENOG4105BZU	Histidine kinase
BM525_01790	ENOG4105C26	Dehydrogenase
BM525_01800	ENOG4105C8Y	Acetylornithine aminotransferase
BM525_01815	ENOG4105C31	Tryptophanyl-tRNA synthetase
BM525_01820	ENOG4105DJV	ribulose-phosphate 3-epimerase
BM525_01840	ENOG4105DFE	Dna adenine methylase
BM525_01850	ENOG4105D49	3-dehydroquinate synthase
BM525_01855	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BM525_01860	ENOG4105E4G	Type IV pilus
BM525_01885	ENOG4108JQC	penicillin-binding protein 1A
BM525_01890	ENOG4107R1I	NAD-dependent malic enzyme
BM525_01900	ENOG4105CYM	Glutathione S-transferase
BM525_01910	ENOG4105CH6	catalase
BM525_01935	ENOG4105BZU	Histidine kinase
BM525_01940	ENOG4107QZM	n-acetylglutamate synthase
BM525_01945	ENOG4105CH7	arginosuccinase
BM525_01950	ENOG4105CDH	Citrulline--aspartate ligase
BM525_01960	ENOG4105CAS	nag kinase
BM525_01965	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
BM525_01970	ENOG4108Z5K	methylglyoxal synthase
BM525_01980	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
BM525_01995	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
BM525_02000	ENOG4105E0F	Histidine kinase
BM525_02005	ENOG4108EUD	Lysophospholipase
BM525_02010	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
BM525_02020	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BM525_02025	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
BM525_02030	ENOG4105VW4	glutaredoxin 3
BM525_02035	ENOG4107YZP	Rhodanese domain protein
BM525_02040	ENOG41063SB	peptidase
BM525_02045	ENOG4105PXI	polysaccharide deacetylase
BM525_02065	ENOG4105DJ4	phosphatidylserine decarboxylase
BM525_02070	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BM525_02075	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
BM525_02105	ENOG4105C7K	acetolactate synthase
BM525_02110	ENOG4108ZP8	Acetolactate synthase small subunit
BM525_02120	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
BM525_02125	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
BM525_02130	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
BM525_02140	ENOG4105F8V	Hydrolase, tatD family
BM525_02150	ENOG4105D52	delta-aminolevulinic acid dehydratase
BM525_02155	ENOG4105C9X	ppx gppa phosphatase
BM525_02160	ENOG4105C1J	atp-dependent rna helicase
BM525_02165	ENOG4105K63	Thioredoxin
BM525_02175	ENOG4105CH2	amidohydrolase
BM525_02180	ENOG4105BZU	Histidine kinase
BM525_02185	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
BM525_02190	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
BM525_02195	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
BM525_02220	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BM525_02230	ENOG4107QR8	Thioredoxin
BM525_02250	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BM525_02255	ENOG4105C26	Dehydrogenase
BM525_02270	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BM525_02275	ENOG4107S6Z	Na H antiporter
BM525_02290	ENOG4105EHZ	conserved protein UCP016719
BM525_02295	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BM525_02300	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BM525_02315	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
BM525_02330	ENOG4105K3M	)-transporter
BM525_02340	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
BM525_02345	ENOG4105I4A	GCN5-related N-acetyltransferase
BM525_02365	ENOG41084S7	Plasmid maintenance system antidote protein
BM525_02435	ENOG4105CHU	acetyl-coa acetyltransferase
BM525_02440	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BM525_02445	ENOG4107SC1	transglycosylase
BM525_02450	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
BM525_02460	ENOG4105EAH	synthase
BM525_02465	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BM525_02470	ENOG4105K46	50S ribosomal protein l27
BM525_02475	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BM525_02490	ENOG4108K5P	(LipO)protein
BM525_02495	ENOG4108UM1	dedA family
BM525_02500	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
BM525_02505	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
BM525_02510	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BM525_02515	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BM525_02520	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
BM525_02530	ENOG4105C8Q	Methyl-accepting chemotaxis
BM525_02565	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
BM525_02570	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
BM525_02575	ENOG4105HF0	Membrane
BM525_02580	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BM525_02585	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BM525_02590	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BM525_02595	ENOG4105BZU	Histidine kinase
BM525_02615	ENOG4105D3G	Pseudouridine synthase
BM525_02620	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
BM525_02635	ENOG4108IAB	Phoh family
BM525_02645	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BM525_02650	ENOG4105C1J	atp-dependent rna helicase
BM525_02665	ENOG4105DFG	type I secretion outer membrane protein
BM525_02670	ENOG41087AY	ADP-Ribose pyrophosphatase
BM525_02680	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
BM525_02685	ENOG4105IPS	esterase
BM525_02690	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BM525_02700	ENOG4107VXZ	Hydrolase
BM525_02725	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
BM525_02730	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BM525_02735	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
BM525_02740	ENOG4105UGU	tonB-dependent Receptor
BM525_02750	ENOG41068WN	
BM525_02755	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BM525_02760	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
BM525_02770	ENOG4105M85	Bola protein
BM525_02800	ENOG4105CHH	sulfate transporter
BM525_02805	ENOG4107QZF	nitrite reductase NADPH large subunit
BM525_02820	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BM525_02825	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BM525_02830	ENOG4107SDU	Methyl-accepting chemotaxis
BM525_02845	ENOG4105D7T	ABC transporter
BM525_02860	ENOG4108Z33	Thiol disulfide Interchange Protein
BM525_02865	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BM525_02870	ENOG4105E27	serine threonine protein kinase
BM525_02875	ENOG4105C58	cytochrome c oxidase accessory protein ccog
BM525_02890	ENOG4105CSU	acyl-Coa dehydrogenase
BM525_02895	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
BM525_02905	ENOG4105CXK	mandelate racemase muconate lactonizing
BM525_02910	ENOG4105MP9	class II Aldolase
BM525_02920	ENOG410624X	efflux transporter, rnd family, mfp subunit
BM525_02925	ENOG4105BZS	acriflavin resistance protein
BM525_02940	ENOG4105C8Q	Methyl-accepting chemotaxis
BM525_02945	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM525_02950	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BM525_02955	ENOG4105KTH	gatB Yqey
BM525_02960	ENOG4105VCC	30S ribosomal protein S21
BM525_02965	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BM525_02975	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
BM525_02980	ENOG4107ZVW	dihydroneopterin aldolase
BM525_02990	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BM525_02995	ENOG4105K59	histidine triad (HIT) protein
BM525_03010	ENOG4105DKK	Benzoate
BM525_03015	ENOG4108JCI	Transcriptional regulator
BM525_03020	ENOG4105DH7	May be involved in recombination (By similarity)
BM525_03025	ENOG4105BZU	Histidine kinase
BM525_03030	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BM525_03035	ENOG4105BZU	Histidine kinase
BM525_03070	ENOG4109015	Biopolymer transport protein exbD tolR
BM525_03075	ENOG41067XB	TonB family
BM525_03085	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BM525_03090	ENOG4105BZU	Histidine kinase
BM525_03095	ENOG4105CEY	Amp-dependent synthetase and ligase
BM525_03110	ENOG4107QIJ	Aconitate hydratase 2
BM525_03115	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BM525_03135	ENOG4107QIJ	Aconitate hydratase 2
BM525_03145	ENOG4105CFH	Aspartokinase
BM525_03150	ENOG4108NVR	Methyl-accepting chemotaxis
BM525_03155	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
BM525_03160	ENOG4105NWN	ApaG protein
BM525_03165	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BM525_03170	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
BM525_03175	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
BM525_03180	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
BM525_03185	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
BM525_03190	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BM525_03195	ENOG4105T95	Thiol disulfide interChange protein
BM525_03200	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BM525_03210	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
BM525_03215	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
BM525_03220	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
BM525_03225	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BM525_03230	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BM525_03235	ENOG4105DXN	mazG family
BM525_03255	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BM525_03260	ENOG4108UJD	30S ribosomal protein S9
BM525_03265	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BM525_03270	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BM525_03275	ENOG4105EIX	cytochrome c1
BM525_03280	ENOG4107MKT	Stringent starvation protein a
BM525_03285	ENOG4105KB2	stringent starvation protein b
BM525_03300	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BM525_03305	ENOG4105CJW	magnesium transporter
BM525_03310	ENOG41080Z8	PHOSPHOCARRIER protein
BM525_03315	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
BM525_03320	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
BM525_03325	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
BM525_03330	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM525_03335	ENOG4108IUZ	ABC transporter
BM525_03340	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
BM525_03350	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
BM525_03355	ENOG4105C2X	Arabinose 5-phosphate isomerase
BM525_03365	ENOG4105DHJ	ABC, transporter
BM525_03370	ENOG4105CY3	ABC transporter, permease
BM525_03375	ENOG4107PE3	Mammalian cell entry related domain protein
BM525_03380	ENOG4105E3I	toluene tolerance
BM525_03390	ENOG4105VFK	BolA family
BM525_03395	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BM525_03400	ENOG4105C0H	protease
BM525_03405	ENOG4105C0H	protease
BM525_03415	ENOG4105D6Z	AFG1 family ATPase
BM525_03420	ENOG4105CDY	transcriptional regulatory protein
BM525_03435	ENOG4105BZU	Histidine kinase
BM525_03440	ENOG4108RCM	Nitroreductase
BM525_03450	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BM525_03465	ENOG4105D05	Receptor
BM525_03470	ENOG4108RNG	Permease of the drug metabolite transporter
BM525_03475	ENOG4105BZU	Histidine kinase
BM525_03495	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BM525_03500	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BM525_03505	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BM525_03510	ENOG4105BZA	Phosphoglycerate kinase
BM525_03515	ENOG4105WYW	fructose-bisphosphate aldolase
BM525_03525	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BM525_03530	ENOG4105C9X	ppx gppa phosphatase
BM525_03545	ENOG4105C8U	phosphate abc transporter
BM525_03555	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BM525_03565	ENOG4105CJ3	phosphate transporter
BM525_03575	ENOG4105C5Q	Transcriptional regulator
BM525_03585	ENOG4108UT2	hemolysin iii
BM525_03590	ENOG4105K56	Transcriptional regulator
BM525_03595	ENOG4108ZHJ	Organic hydroperoxide resistance protein
BM525_03610	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
BM525_03620	ENOG4107SDU	Methyl-accepting chemotaxis
BM525_03630	ENOG4105HEI	LysR family (Transcriptional regulator
BM525_03635	ENOG4107QM2	Aldo Keto reductase
BM525_03650	ENOG4107RH8	nuclease SbcCD subunit D
BM525_03655	ENOG4105EYH	Exonuclease
BM525_03665	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
BM525_03685	ENOG4105CI2	imidazolone-5-propionate hydrolase
BM525_03690	ENOG4105CZE	histidine utilization repressor
BM525_03695	ENOG4105CGP	Urocanate hydratase
BM525_03700	ENOG4105C84	Histidine ammonia-lyase
BM525_03725	ENOG4105C5H	ABC transporter
BM525_03750	ENOG4105D64	Mechanosensitive ion channel
BM525_03775	ENOG4108NSC	Pfam:DUF88
BM525_03780	ENOG4108KU3	Integrase
BM525_03785	ENOG4108HMN	Caspase domain
BM525_03825	ENOG4107SV5	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
BM525_03830	ENOG4107IIZ	CRISPR-associated helicase, Cas3
BM525_03885	ENOG41067MG	lrgb family
BM525_03915	ENOG4105CSA	Coproporphyrinogen iii oxidase
BM525_03925	ENOG4105C1J	atp-dependent rna helicase
BM525_03930	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BM525_03945	ENOG4105CPI	Metal Dependent Phosphohydrolase
BM525_03950	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BM525_03955	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BM525_03960	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BM525_03965	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BM525_03980	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BM525_03985	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BM525_03990	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BM525_04000	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BM525_04005	ENOG4108IUW	ABC transporter
BM525_04010	ENOG4108SDH	ABC, transporter
BM525_04020	ENOG4107EXC	regulatoR
BM525_04050	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
BM525_04055	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
BM525_04060	ENOG41060IM	Heme exporter protein
BM525_04065	ENOG4105X3C	heme exporter protein
BM525_04070	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
BM525_04075	ENOG4105DA4	cytochrome c-type biogenesis protein
BM525_04080	ENOG4107QX9	Thiol disulfide interChange protein
BM525_04085	ENOG4108M1T	Cytochrome c-type biogenesis protein
BM525_04095	ENOG410903C	(LipO)protein
BM525_04100	ENOG4105CMR	udp-glucose 4-epimerase
BM525_04110	ENOG4105DUX	Transporter
BM525_04140	ENOG4105ESV	Glycosyl transferase, family 4
BM525_04155	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BM525_04160	ENOG4105KQC	Competence protein
BM525_04165	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BM525_04180	ENOG4105EWT	decarboxylase family
BM525_04185	ENOG4105BZU	Histidine kinase
BM525_04190	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
BM525_04195	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
BM525_04230	ENOG4105DR9	pseudouridine synthase
BM525_04235	ENOG4105QDK	Flavodoxin
BM525_04240	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
BM525_04245	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
BM525_04250	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BM525_04255	ENOG4105CE9	30S ribosomal protein S2
BM525_04260	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BM525_04265	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BM525_04270	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BM525_04275	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BM525_04280	ENOG4105KNE	Phosphatidate cytidylyltransferase
BM525_04285	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
BM525_04295	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM525_04300	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
BM525_04305	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BM525_04310	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BM525_04315	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BM525_04320	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BM525_04325	ENOG4105C0B	DNA polymerase III (alpha subunit)
BM525_04330	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
BM525_04335	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BM525_04340	ENOG4105BZU	Histidine kinase
BM525_04355	ENOG4108Z6B	deaminase
BM525_04360	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
BM525_04365	ENOG4108ETH	Formylglycinamide ribotide synthetase
BM525_04370	ENOG4108DG9	Smr protein MutS2
BM525_04390	ENOG4105CDV	Ompa motb domain protein
BM525_04395	ENOG4108JJA	ABC, transporter
BM525_04405	ENOG4105WH1	Two component transcriptional regulator luxr family
BM525_04445	ENOG4107R88	Chemotaxis protein (CheV)
BM525_04450	ENOG4105BZU	Histidine kinase
BM525_04455	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
BM525_04460	ENOG4108ZC9	flagellar basal-body rod protein flgc
BM525_04465	ENOG4105W00	Flagellar hook capping protein
BM525_04470	ENOG4105BZE	flagellar hook protein, FlgE
BM525_04475	ENOG4108KPB	Flagellar basal-body rod protein FlgF
BM525_04480	ENOG4105CGA	flagellar basal-body rod protein FlgG
BM525_04485	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
BM525_04490	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
BM525_04495	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
BM525_04500	ENOG4105E1Q	flagellar hook-associated protein
BM525_04515	ENOG4105I03	Flagellin
BM525_04520	ENOG4105I03	Flagellin
BM525_04525	ENOG4105I03	Flagellin
BM525_04530	ENOG41063QE	flagellar protein FlaG
BM525_04540	ENOG4105MQ3	flagellar protein FliS
BM525_04555	ENOG4108IAJ	Nad-dependent epimerase dehydratase
BM525_04560	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BM525_04575	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
BM525_04590	ENOG4108TN2	lmbE family
BM525_04600	ENOG4105D2T	synthase
BM525_04610	ENOG4108S0S	Nucleotidyl transferase
BM525_04615	ENOG4105F0R	Cytidylyltransferase
BM525_04630	ENOG4105CHR	reductase
BM525_04635	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BM525_04650	ENOG4105D2T	synthase
BM525_04660	ENOG4105F0R	Cytidylyltransferase
BM525_04665	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BM525_04670	ENOG4105C5E	polysaccharide biosynthesis protein
BM525_04675	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
BM525_04685	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM525_04690	ENOG4105BZU	Histidine kinase
BM525_04695	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM525_04700	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
BM525_04705	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
BM525_04710	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BM525_04720	ENOG4108JIR	Flagellum-specific ATP synthase
BM525_04740	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BM525_04745	ENOG4105DD5	Flagellar motor switch protein
BM525_04750	ENOG4105VTB	flagellar biosynthesis protein fliO
BM525_04755	ENOG4105CN7	Flagellar biosynthetic protein FliP
BM525_04760	ENOG4105VS8	Flagellar biosynthetic protein fliq
BM525_04765	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
BM525_04770	ENOG4105D00	flagellar biosynthetic protein flhB
BM525_04775	ENOG4105D7B	Flagellar biosynthesis protein flha
BM525_04780	ENOG4105FZW	flagellar biosynthesis regulator FlhF
BM525_04790	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM525_04795	ENOG4108VYJ	response regulator receiver protein
BM525_04800	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
BM525_04805	ENOG4105CBS	Chea signal transduction histidine kinase
BM525_04815	ENOG4107QJE	Chromosome Partitioning Protein
BM525_04825	ENOG4105YFD	chemotaxis, protein
BM525_04835	ENOG4105CVG	Homoserine O-transsuccinylase
BM525_04840	ENOG4105C3R	Methionine synthase
BM525_04845	ENOG4105C3R	Methionine synthase
BM525_04855	ENOG4105NBK	UPF0345 protein
BM525_04860	ENOG4105C8Q	Methyl-accepting chemotaxis
BM525_04865	ENOG4105DZ2	Transcriptional regulator
BM525_04870	ENOG4105C5Q	Transcriptional regulator
BM525_04875	ENOG4107B2H	carbonic anhydrase
BM525_04880	ENOG4105CHH	sulfate transporter
BM525_04895	ENOG4105C9K	Endothelin-converting enzyme 1
BM525_04905	ENOG4108004	Modulates RecA activity (By similarity)
BM525_04910	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BM525_04915	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
BM525_04940	ENOG4107QSA	Oxaloacetate decarboxylase
BM525_04945	ENOG4105D9Q	decarboxylase (Beta subunit)
BM525_04950	ENOG4108JQ2	peptide transport system atp-binding protein
BM525_04955	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
BM525_04960	ENOG4108EU3	peptide transport system, permease
BM525_04965	ENOG4108I5W	peptide transport system, permease protein
BM525_04970	ENOG4105DEF	Extracellular solute-binding protein, family 5
BM525_04975	ENOG4105E51	psp operon transcriptional activator
BM525_04980	ENOG41087YS	Phage shock protein A
BM525_04995	ENOG4105MIR	Phenylalanine 4-monooxygenase
BM525_05010	ENOG4108RXX	maleylacetoacetate isomerase
BM525_05015	ENOG4108XM1	transcriptional regulator AsnC family
BM525_05035	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
BM525_05040	ENOG4108KPZ	tonB-dependent Receptor
BM525_05090	ENOG4109015	Biopolymer transport protein exbD tolR
BM525_05095	ENOG410822N	TonB family
BM525_05105	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
BM525_05145	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
BM525_05160	ENOG4105HEI	LysR family (Transcriptional regulator
BM525_05165	ENOG4105F27	Major Facilitator
BM525_05170	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
BM525_05175	ENOG4105CV8	reductase
BM525_05185	ENOG4105BZU	Histidine kinase
BM525_05190	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
BM525_05195	ENOG4105C75	arginyL-tRNA synthetase
BM525_05245	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
BM525_05255	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BM525_05260	ENOG4105CRK	lysyL-tRNA synthetase
BM525_05270	ENOG4108W1A	pseudouridine synthase
BM525_05285	ENOG4105D9M	gamma-glutamylcysteine synthetase
BM525_05300	ENOG4108DG9	Smr protein MutS2
BM525_05305	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
BM525_05310	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BM525_05320	ENOG4105ED1	spovr family
BM525_05325	ENOG4106AKX	UPF0229 protein
BM525_05330	ENOG4105CYN	Serine protein kinase
BM525_05335	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BM525_05340	ENOG4105M2J	Glutaredoxin
BM525_05345	ENOG4105D05	Receptor
BM525_05370	ENOG4105D3R	alkyl hydroperoxide reductase
BM525_05375	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
BM525_05380	ENOG4105EIY	sodium-type flagellar protein motY
BM525_05385	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
BM525_05390	ENOG4108UYE	Lactoylglutathione lyase
BM525_05395	ENOG4105VEQ	Cold shock protein
BM525_05415	ENOG4105DZB	Electron transport complex
BM525_05420	ENOG4108UQQ	Electron transport complex
BM525_05425	ENOG4105D6A	Electron transport complex
BM525_05435	ENOG4108R3D	Electron transport complex
BM525_05440	ENOG4105DGN	Electron transport complex
BM525_05455	ENOG4107QJQ	Mate efflux family protein
BM525_05460	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BM525_05470	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
BM525_05475	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
BM525_05485	ENOG4105CAQ	asparagine synthetase
BM525_05515	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
BM525_05520	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
BM525_05525	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
BM525_05530	ENOG4105C11	sulfate adenylyltransferase), subunit 2
BM525_05535	ENOG4105CK7	Sodium proline symporter
BM525_05540	ENOG4105BZU	Histidine kinase
BM525_05585	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BM525_05590	ENOG4105CHU	acetyl-coa acetyltransferase
BM525_05595	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BM525_05605	ENOG4105BZU	Histidine kinase
BM525_05615	ENOG4108BY2	phosphohistidine phosphatase
BM525_05625	ENOG4108JU6	CBS domain protein
BM525_05630	ENOG4106KVJ	cytochrome C assembly protein
BM525_05635	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BM525_05680	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
BM525_05685	ENOG4105BZ1	(ABC) transporter
BM525_05700	ENOG4105K5M	30s ribosomal protein S16
BM525_05705	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BM525_05710	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BM525_05715	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BM525_05720	ENOG4105EN6	Membrane
BM525_05725	ENOG4105E39	Enoyl-CoA hydratase
BM525_05730	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
BM525_05750	ENOG4108ZJT	translation initiation factor, Sui1
BM525_05760	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BM525_05770	ENOG4105BZU	Histidine kinase
BM525_05780	ENOG4107WP9	Histidine kinase
BM525_05790	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM525_05795	ENOG4105I03	Flagellin
BM525_05810	ENOG4105C9M	aspartyl-trna synthetase
BM525_05815	ENOG4108TIT	dATP pyrophosphohydrolase
BM525_05820	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
BM525_05825	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BM525_05830	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BM525_05835	ENOG4107YD3	Thioesterase
BM525_05840	ENOG4105E02	MotA TolQ exbB proton channel
BM525_05845	ENOG4105M8F	Biopolymer transport protein exbD tolR
BM525_05855	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
BM525_05860	ENOG4105KCK	Peptidoglycan-associated lipoprotein
BM525_05865	ENOG4105UFD	tol-pal system protein YbgF
BM525_05885	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
BM525_05900	ENOG4108NRW	Phospholipase, patatin family
BM525_05905	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
BM525_05920	ENOG4108W6C	Dehydrogenase
BM525_05925	ENOG4105DS1	cytochrome b561
BM525_05940	ENOG4105BZU	Histidine kinase
BM525_05955	ENOG4105HEI	LysR family (Transcriptional regulator
BM525_05960	ENOG4105DQ4	alcohol dehydrogenase
BM525_05965	ENOG4108VKG	metal-dependent hydrolase
BM525_05970	ENOG4105BZS	acriflavin resistance protein
BM525_05980	ENOG4108XG4	DNA-binding transcriptional regulator
BM525_05985	ENOG4108ESX	Receptor
BM525_06005	ENOG4105BZU	Histidine kinase
BM525_06015	ENOG4105DY2	Paraquat-inducible protein b
BM525_06020	ENOG4105F1S	paraquat-inducible protein a
BM525_06035	ENOG4105EMU	Dehydrogenase
BM525_06040	ENOG4105CF7	AraC family transcriptional regulator
BM525_06045	ENOG4105C5S	asparaginyl-tRNA synthetase
BM525_06060	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
BM525_06080	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
BM525_06085	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
BM525_06090	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BM525_06095	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
BM525_06100	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
BM525_06105	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
BM525_06110	ENOG4105KJF	protein tyrosine phosphatase
BM525_06115	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
BM525_06120	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
BM525_06125	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
BM525_06140	ENOG4108JJ7	ABC transporter
BM525_06145	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BM525_06155	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BM525_06175	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BM525_06205	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
BM525_06220	ENOG4108UJV	acyl-CoA thioesterase i
BM525_06225	ENOG4108I0Y	(ABC) transporter
BM525_06230	ENOG4105CV6	ABC transporter, permease
BM525_06235	ENOG4105ECP	epimerase
BM525_06240	ENOG4105KKP	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
BM525_06245	ENOG4105DSF	transport protein
BM525_06255	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BM525_06270	ENOG4105K9H	YciI-like protein
BM525_06275	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
BM525_06280	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BM525_06285	ENOG4105DK0	Indole-3-glycerol phosphate synthase
BM525_06290	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BM525_06300	ENOG4105CRQ	synthase (Component I)
BM525_06305	ENOG4105DB7	PHP domain protein
BM525_06310	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
BM525_06315	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
BM525_06320	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
BM525_06325	ENOG4105FE9	pseudouridine synthase
BM525_06330	ENOG4105CV8	reductase
BM525_06335	ENOG4108UW5	maltose o-acetyltransferase
BM525_06345	ENOG4106BRA	Membrane
BM525_06360	ENOG4108JJ6	Type I secretion system ATPase
BM525_06370	ENOG4105FQ6	thiopurine methyltransferase
BM525_06375	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BM525_06380	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BM525_06385	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
BM525_06390	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BM525_06395	ENOG4105C0A	alcohol dehydrogenase
BM525_06400	ENOG4105DTD	Dehydrogenase
BM525_06410	ENOG4105DWV	Homoserine O-trans-acetylase
BM525_06415	ENOG4105CY2	Citrate transporter
BM525_06430	ENOG4105BZU	Histidine kinase
BM525_06450	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BM525_06455	ENOG4105CFG	Acts as a chaperone (By similarity)
BM525_06460	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BM525_06465	ENOG41085AF	Cytochrome
BM525_06475	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BM525_06485	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
BM525_06490	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BM525_06495	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
BM525_06500	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BM525_06520	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
BM525_06525	ENOG4105C6K	Malic enzyme
BM525_06540	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
BM525_06545	ENOG4108JU5	Magnesium and cobalt efflux protein
BM525_06550	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BM525_06555	ENOG4105C9A	Phoh family
BM525_06560	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BM525_06565	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
BM525_06590	ENOG4107RNH	Outer membrane receptor FepA
BM525_06595	ENOG4108S4H	thioesterase Superfamily protein
BM525_06600	ENOG4107XWI	flavin reductase domain protein, FMN-binding
BM525_06645	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BM525_06650	ENOG4105C3G	gtp-binding protein
BM525_06655	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BM525_06660	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BM525_06665	ENOG4105DQ4	alcohol dehydrogenase
BM525_06680	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BM525_06690	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BM525_06695	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
BM525_06700	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
BM525_06705	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BM525_06710	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BM525_06715	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BM525_06720	ENOG4108YY7	Invasion gene expression up-regulator SirB
BM525_06725	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
BM525_06735	ENOG4105ETT	transcriptional Regulator, LysR family
BM525_06745	ENOG4105M08	Membrane
BM525_06750	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
BM525_06755	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BM525_06760	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
BM525_06765	ENOG4107TPY	serine threonine protein kinase
BM525_06770	ENOG4105TMB	Formate nitrite transporter
BM525_06775	ENOG4105F8C	transglutaminase domain-containing protein
BM525_06785	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BM525_06790	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
BM525_06795	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
BM525_06800	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
BM525_06805	ENOG4105BZU	Histidine kinase
BM525_06810	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
BM525_06820	ENOG4105K8R	UPF0145 protein
BM525_06840	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BM525_06845	ENOG4105KUZ	arsenate reductase
BM525_06850	ENOG4107RBJ	symporter
BM525_06870	ENOG4105F1J	Homogentisate 1,2-dioxygenase
BM525_06890	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BM525_06900	ENOG4105BZU	Histidine kinase
BM525_06905	ENOG4105BZU	Histidine kinase
BM525_06925	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
BM525_06950	ENOG4105BZU	Histidine kinase
BM525_06960	ENOG4107QUY	Guanine deaminase
BM525_06980	ENOG4105C7W	Xanthine dehydrogenase
BM525_06995	ENOG4108R86	Transcriptional regulator
BM525_07010	ENOG4105C7N	Xanthine uracil vitamin C permease
BM525_07015	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
BM525_07025	ENOG4105BZU	Histidine kinase
BM525_07035	ENOG4105BZU	Histidine kinase
BM525_07045	ENOG4105C2W	permease
BM525_07060	ENOG4105C5R	Aminotransferase
BM525_07065	ENOG4105HF0	Membrane
BM525_07070	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BM525_07105	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
BM525_07115	ENOG4105C22	threonyL-tRNA synthetase
BM525_07120	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BM525_07125	ENOG41082NX	50s ribosomal protein l35
BM525_07130	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BM525_07140	ENOG4105D3Q	Sugar transferase
BM525_07150	ENOG4105DAY	polysaccharide export protein
BM525_07155	ENOG4108QV3	biosynthesis protein
BM525_07160	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
BM525_07185	ENOG4105BZU	Histidine kinase
BM525_07195	ENOG4107QPH	glycogen) synthase
BM525_07225	ENOG4107T8Q	Glycosyl transferase (Group 1
BM525_07230	ENOG4105C74	pyruvyl transferase
BM525_07250	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BM525_07255	ENOG4105JEU	Glycosyl transferase, family 2
BM525_07260	ENOG4105EXC	Acyl-transferase
BM525_07275	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BM525_07280	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BM525_07285	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
BM525_07295	ENOG4108Z66	YbaK ebsC protein
BM525_07305	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
BM525_07310	ENOG4108WBT	adenosyltransferase
BM525_07320	ENOG4108JA2	transcriptioN-repair coupling factor
BM525_07330	ENOG4105D60	lipoprotein releasing system transmembrane protein
BM525_07355	ENOG4105CGK	Exodeoxyribonuclease III
BM525_07390	ENOG4105DNH	Major Facilitator
BM525_07400	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
BM525_07420	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
BM525_07430	ENOG4108UKI	Enoyl-CoA hydratase
BM525_07435	ENOG4107QX3	carboxylase
BM525_07440	ENOG4105C1G	acyl-Coa dehydrogenase
BM525_07445	ENOG4108Z6Z	Transcriptional regulator
BM525_07450	ENOG4105CHU	acetyl-coa acetyltransferase
BM525_07465	ENOG4105BZU	Histidine kinase
BM525_07475	ENOG4105CJB	Exodeoxyribonuclease I
BM525_07480	ENOG4105BZU	Histidine kinase
BM525_07485	ENOG4105D44	asparaginase
BM525_07525	ENOG4105CQ7	ATP-dependent helicase
BM525_07540	ENOG4105DR4	Methyltransferase
BM525_07545	ENOG4108JA1	polyketide synthase
BM525_07550	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BM525_07555	ENOG4107RZZ	dna polymerase iii epsilon subunit
BM525_07575	ENOG4108M8H	domain protein
BM525_07585	ENOG4105D60	lipoprotein releasing system transmembrane protein
BM525_07590	ENOG4105CK2	sodium dicarboxylate symporter
BM525_07600	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
BM525_07610	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BM525_07625	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
BM525_07630	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
BM525_07635	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
BM525_07655	ENOG4105JQN	Transcriptional regulator
BM525_07660	ENOG4107YB6	acetyltransferase, (GNAT) family
BM525_07675	ENOG4105C03	ribonuclease
BM525_07680	ENOG4105EI2	Pseudouridine synthase
BM525_07695	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
BM525_07700	ENOG4105VGS	50s ribosomal protein l32
BM525_07705	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
BM525_07710	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BM525_07715	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
BM525_07720	ENOG4105CHR	reductase
BM525_07725	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BM525_07730	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BM525_07740	ENOG4105HHA	aminodeoxychorismate lyase
BM525_07745	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BM525_07750	ENOG4107QRG	dna polymerase iii
BM525_07755	ENOG4105F8V	Hydrolase, tatD family
BM525_07770	ENOG4105BZU	Histidine kinase
BM525_07790	ENOG4105CHR	reductase
BM525_07795	ENOG4108J2P	Alpha beta hydrolase fold
BM525_07805	ENOG4105CHU	acetyl-coa acetyltransferase
BM525_07810	ENOG4105CSU	acyl-Coa dehydrogenase
BM525_07825	ENOG4105DKT	Transcriptional regulator
BM525_07830	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
BM525_07840	ENOG4105DEI	Mannitol dehydrogenase
BM525_07865	ENOG4105D8X	mechanosensitive ion channel
BM525_07870	ENOG4105D05	Receptor
BM525_07875	ENOG4105KZX	Pterin carbinolamine dehydratase
BM525_07895	ENOG4105BZU	Histidine kinase
BM525_07900	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BM525_07905	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
BM525_07910	ENOG4105CHV	Transcription elongation factor NusA
BM525_07915	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BM525_07920	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BM525_07925	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BM525_07935	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BM525_07940	ENOG4105BZU	Histidine kinase
BM525_07945	ENOG4105FE9	pseudouridine synthase
BM525_07955	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
BM525_07985	ENOG4105D3R	alkyl hydroperoxide reductase
BM525_08030	ENOG4105CCT	upf0313 protein
BM525_08045	ENOG4105D05	Receptor
BM525_08050	ENOG4107QN2	dihydrolipoyl dehydrogenase
BM525_08060	ENOG4105VNH	ABC transporter solute-binding protein
BM525_08070	ENOG4108VGW	abc transporter atp-binding protein
BM525_08075	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
BM525_08115	ENOG4105CBN	LysR family transcriptional regulator
BM525_08135	ENOG4105CJ1	ABC, transporter
BM525_08150	ENOG4105DMT	epimerase dehydratase
BM525_08155	ENOG4105C09	Bile acid
BM525_08215	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BM525_08220	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BM525_08225	ENOG4108Z1B	Cyclase dehydrase
BM525_08230	ENOG4105VDB	UPF0125 protein
BM525_08240	ENOG4105C94	Transporter
BM525_08250	ENOG4107RDJ	Sulfotransferase
BM525_08260	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
BM525_08265	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
BM525_08300	ENOG4105EZE	Cupin 4 family protein
BM525_08310	ENOG4107QTF	adenylosuccinate lyase
BM525_08315	ENOG41075W9	High frequency lysogenization protein HflD homolog
BM525_08320	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BM525_08325	ENOG4108R99	pseudouridine synthase
BM525_08330	ENOG4105E9K	Isocitrate dehydrogenase
BM525_08335	ENOG4105VEQ	Cold shock protein
BM525_08340	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
BM525_08345	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BM525_08350	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BM525_08355	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
BM525_08360	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
BM525_08365	ENOG4105C3M	thioredoxin reductase
BM525_08370	ENOG4105PQ6	UPF0208 membrane protein
BM525_08375	ENOG4105GPY	SprT protein
BM525_08380	ENOG4105D07	Signal peptide peptidase, SppA
BM525_08395	ENOG41069NU	Nitroreductase
BM525_08405	ENOG4105HDK	L-asparaginase
BM525_08410	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
BM525_08415	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
BM525_08420	ENOG4108Z43	UPF0250 protein
BM525_08425	ENOG4105DZ1	carboxypeptidase
BM525_08430	ENOG4105K6T	rare lipoprotein A
BM525_08435	ENOG4105CNI	cell division protein FtsW
BM525_08440	ENOG4105CJN	penicillin-binding protein
BM525_08445	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
BM525_08450	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
BM525_08460	ENOG4105DJF	DNA polymerase III, delta' subunit
BM525_08465	ENOG4108U2H	Rare lipoprotein B
BM525_08470	ENOG4105C8T	Leucyl-tRNA synthetase
BM525_08480	ENOG4105DAN	ATP-dependent protease
BM525_08485	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
BM525_08490	ENOG4105BZU	Histidine kinase
BM525_08500	ENOG4105HBR	Rna-binding protein
BM525_08505	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
BM525_08510	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BM525_08515	ENOG4105EEI	dihydropteroate synthase
BM525_08520	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BM525_08525	ENOG4105CP7	Triose-phosphate isomerase
BM525_08540	ENOG4105BZU	Histidine kinase
BM525_08570	ENOG4105CHR	reductase
BM525_08575	ENOG4108KP7	hydrolase
BM525_08590	ENOG4105CK7	Sodium proline symporter
BM525_08600	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BM525_08615	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BM525_08675	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BM525_08760	ENOG410822N	TonB family
BM525_08790	ENOG4105EXN	Sulfate transport protein CysZ
BM525_08795	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
BM525_08800	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
BM525_08805	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BM525_08820	ENOG4105BZ1	(ABC) transporter
BM525_08825	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
BM525_08830	ENOG4105W49	UPF0434 protein
BM525_08835	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
BM525_08845	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
BM525_08860	ENOG4105CUZ	uba thif-type nad fad binding protein
BM525_08865	ENOG4105CHF	Glutathione S-transferase
BM525_08870	ENOG4105EUB	pirin domain protein
BM525_08875	ENOG4107QKV	phosphomannomutase
BM525_08885	ENOG4105BZN	citrate synthase
BM525_08890	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
BM525_08895	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
BM525_08900	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
BM525_08905	ENOG4105E33	succinate dehydrogenase
BM525_08910	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
BM525_08915	ENOG4105C7S	Dehydrogenase
BM525_08920	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
BM525_08925	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
BM525_08950	ENOG4105QV4	Tryptophan halogenase
BM525_08965	ENOG4108NRW	Phospholipase, patatin family
BM525_08985	ENOG4108IUK	alpha amylase, catalytic
BM525_09000	ENOG4105ETE	Transcriptional regulator (LacI family
BM525_09005	ENOG4105CX6	glutaminyL-tRNA synthetase
BM525_09010	ENOG4105UBK	short-chain dehydrogenase reductase
BM525_09015	ENOG4108M0H	Extracellular lipase
BM525_09020	ENOG4107SQI	penicillin amidase
BM525_09025	ENOG4105ERU	peptidase
BM525_09040	ENOG4107QNR	UPF0135 protein
BM525_09045	ENOG4106371	Methyltransferase
BM525_09050	ENOG4105C5I	Dehydrogenase
BM525_09055	ENOG4108V06	Glutathione peroxidase
BM525_09060	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BM525_09070	ENOG4105C1G	acyl-Coa dehydrogenase
BM525_09075	ENOG4105E39	Enoyl-CoA hydratase
BM525_09080	ENOG4105DHI	Methyltransferase
BM525_09085	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
BM525_09090	ENOG4105E68	Sulfatase
BM525_09095	ENOG4105YDX	UPF0352 protein
BM525_09100	ENOG4106V8H	Nucleoid-associated protein
BM525_09130	ENOG4108HRK	Histidine kinase
BM525_09135	ENOG4108VAC	response regulator
BM525_09140	ENOG4105CTQ	phosphohexokinase
BM525_09150	ENOG4105W1Y	Transcriptional regulator
BM525_09165	ENOG4105PGM	cation diffusion facilitator family transporter
BM525_09200	ENOG4105BZU	Histidine kinase
BM525_09210	ENOG4105C72	UPF0176 protein
BM525_09220	ENOG4105C1J	atp-dependent rna helicase
BM525_09230	ENOG4105D6N	CoA-transferase, subunit a
BM525_09235	ENOG4105F04	LysR family Transcriptional regulator
BM525_09250	ENOG4107R11	Transcriptional regulator
BM525_09255	ENOG4105EJQ	L-serine dehydratase
BM525_09265	ENOG4105CRQ	synthase (Component I)
BM525_09275	ENOG4105CGY	Dna recombination protein
BM525_09280	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
BM525_09290	ENOG4105CPP	Dehydrogenase, E1 component
BM525_09300	ENOG4105D6S	protein involved in catabolism of external DNA
BM525_09310	ENOG4105C29	acyl-CoA thioesterase
BM525_09315	ENOG4108Z0R	Transferase
BM525_09320	ENOG4105C5R	Aminotransferase
BM525_09330	ENOG4108ZGC	gaf domain protein
BM525_09340	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
BM525_09345	ENOG4105CN1	protease
BM525_09350	ENOG4105C8J	)-transporter
BM525_09355	ENOG4105DFD	Na H antiporter
BM525_09360	ENOG4105CD8	aminopeptidase N
BM525_09375	ENOG4105D25	secreted protein
BM525_09390	ENOG4105C7I	Dehydrogenase
BM525_09395	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
BM525_09400	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
BM525_09410	ENOG4105C5H	ABC transporter
BM525_09420	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
BM525_09425	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
BM525_09435	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BM525_09440	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BM525_09445	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BM525_09450	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
BM525_09465	ENOG4105DUU	IucA IucC family protein
BM525_09470	ENOG4105CEY	Amp-dependent synthetase and ligase
BM525_09475	ENOG41086VD	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BM525_09480	ENOG4108WBH	protein TIM barrel
BM525_09510	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BM525_09520	ENOG41080IJ	Diacylglycerol kinase
BM525_09525	ENOG41081QV	Universal stress protein
BM525_09535	ENOG4105CBC	glutamate synthase
BM525_09540	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
BM525_09545	ENOG4108UQY	Iron-storage protein
BM525_09560	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
BM525_09575	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
BM525_09600	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
BM525_09605	ENOG4105Q9Y	Universal stress protein
BM525_09610	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
BM525_09615	ENOG4105D78	K07001 NTE family protein
BM525_09640	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
BM525_09645	ENOG4105KHC	sulfurtransferase
BM525_09650	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
BM525_09655	ENOG4106IUH	DTW domain containing protein
BM525_09665	ENOG4108MN8	Membrane
BM525_09670	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
BM525_09685	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
BM525_09705	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BM525_09710	ENOG4105WMR	Protein CrcB homolog
BM525_09715	ENOG4105D1H	recombination factor protein RarA
BM525_09725	ENOG4105CNU	cell division protein FtsK
BM525_09730	ENOG4105EW9	transcriptional regulator AsnC family
BM525_09735	ENOG4105DCF	alanine dehydrogenase
BM525_09740	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
BM525_09745	ENOG4105CFV	Tetratricopeptide repeat protein
BM525_09760	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
BM525_09765	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BM525_09770	ENOG4105CAT	Cytidine monophosphate kinase
BM525_09775	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BM525_09780	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
BM525_09785	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BM525_09790	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
BM525_09795	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BM525_09800	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BM525_09805	ENOG4105XPH	Ferredoxin
BM525_09820	ENOG4105BZU	Histidine kinase
BM525_09830	ENOG4105C8V	SAICAR synthetase
BM525_09835	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BM525_09840	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BM525_09850	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BM525_09860	ENOG4105ERG	peptidase m48, ste24p
BM525_09870	ENOG4105K89	arsenate reductase
BM525_09875	ENOG4105CS1	NAD(P)H quinone oxidoreductase
BM525_09885	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
BM525_09895	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BM525_09900	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
BM525_09910	ENOG4107QPN	acyl-Coa dehydrogenase
BM525_09925	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
BM525_09930	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
BM525_09935	ENOG4105DBI	uridine monophosphokinase
BM525_09940	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
BM525_09945	ENOG4105C3Q	Glycosyl transferase, family 2
BM525_09950	ENOG4107QW3	Sucrose phosphorylase
BM525_09955	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BM525_09960	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BM525_09965	ENOG4107QI1	Mate efflux family protein
BM525_09985	ENOG4105C6T	cysteine synthase
BM525_10045	ENOG4105FQP	Beta-lactamase
BM525_10170	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BM525_10180	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BM525_10185	ENOG41060WC	Enoyl-CoA hydratase
BM525_10205	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
BM525_10215	ENOG4105C28	cystathionine
BM525_10230	ENOG4105CGF	Aromatic amino acid aminotransferase
BM525_10245	ENOG4108UPT	UPF0178 protein
BM525_10250	ENOG4105CHR	reductase
BM525_10255	ENOG4105CHR	reductase
BM525_10260	ENOG4105CSU	acyl-Coa dehydrogenase
BM525_10265	ENOG4105FTV	AraC Family Transcriptional Regulator
BM525_10290	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
BM525_10300	ENOG4105C10	Electron transfer flavoprotein
BM525_10305	ENOG4105BZJ	Electron transfer flavoprotein
BM525_10310	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
BM525_10315	ENOG4108YX2	DNA-binding protein
BM525_10320	ENOG4105EV9	Alpha Beta Hydrolase
BM525_10330	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
BM525_10335	ENOG4108NVR	Methyl-accepting chemotaxis
BM525_10340	ENOG41090R7	Ferric uptake
BM525_10355	ENOG4105P4J	Allophanate hydrolase, subunit 1
BM525_10360	ENOG4105E7W	lamb ycsf family protein
BM525_10365	ENOG4105QNR	S1 RNA binding domain protein
BM525_10370	ENOG4108UKZ	OsmC family
BM525_10375	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
BM525_10400	ENOG4105CHM	Aminotransferase
BM525_10405	ENOG4105DK2	UPF0207 protein
BM525_10410	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
BM525_10435	ENOG4105K5B	UPF0225 protein
BM525_10440	ENOG4105BZU	Histidine kinase
BM525_10455	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
BM525_10465	ENOG4105C1G	acyl-Coa dehydrogenase
BM525_10475	ENOG4107ZSV	Receptor
BM525_10495	ENOG4105D4P	Coproporphyrinogen iii oxidase
BM525_10500	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
BM525_10505	ENOG4105E0C	molybdate abc transporter
BM525_10515	ENOG4108ZAF	Molybdopterin
BM525_10520	ENOG4105M00	molybdopterin converting factor, subunit 1
BM525_10530	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
BM525_10535	ENOG4105D06	uba thif-type nad fad binding protein
BM525_10550	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
BM525_10570	ENOG4105EG6	Saccharopine dehydrogenase
BM525_10575	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BM525_10595	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
BM525_10600	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BM525_10610	ENOG4107AQZ	Membrane
BM525_10625	ENOG4107QYX	exodeoxyribonuclease v alpha
BM525_10630	ENOG4107QKA	exodeoxyribonuclease V beta
BM525_10635	ENOG4105DSY	exodeoxyribonuclease V, gamma
BM525_10645	ENOG4108IQE	Amp-dependent synthetase and ligase
BM525_10670	ENOG4105CVI	Transcriptional regulator
BM525_10685	ENOG41082SX	arsR family transcriptional regulator
BM525_10695	ENOG4105DUM	transcriptional regulator, lysR family
BM525_10705	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM525_10750	ENOG4105DK2	UPF0207 protein
BM525_10775	ENOG4105VUT	cytoplasmic protein
BM525_10790	ENOG4105BZG	amino acid carrier protein
BM525_10810	ENOG4105E0X	reductase
BM525_10815	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
BM525_10825	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BM525_10830	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
BM525_10835	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BM525_10840	ENOG4105DSB	aldose 1-epimerase
BM525_10845	ENOG4108UHU	Aldolase
BM525_10850	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BM525_10855	ENOG4105C01	Dihydroxy-acid dehydratase
BM525_10860	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
BM525_10865	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
BM525_10870	ENOG4106KNT	transcriptional regulator
BM525_10875	ENOG4105CA9	Pyruvate kinase
BM525_10880	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BM525_10895	ENOG4105K3G	Periplasmic Protein
BM525_10925	ENOG4105EIG	urea carboxylase-associated protein 1
BM525_10945	ENOG4105CHR	reductase
BM525_10955	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
BM525_10960	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
BM525_10965	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
BM525_10970	ENOG4105ETE	Transcriptional regulator (LacI family
BM525_10975	ENOG4105CTX	dehydratase
BM525_10980	ENOG4105D2H	Uronic isomerase
BM525_10985	ENOG4105DEI	Mannitol dehydrogenase
BM525_10990	ENOG4108UHU	Aldolase
BM525_10995	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
BM525_11010	ENOG4107XII	Glycosyl Hydrolase Family 88
BM525_11020	ENOG4105BZU	Histidine kinase
BM525_11035	ENOG4108K8S	endonuclease I
BM525_11040	ENOG4105C8Q	Methyl-accepting chemotaxis
BM525_11055	ENOG4108W5M	transcriptional regulator
BM525_11060	ENOG4108I6A	alcohol dehydrogenase
BM525_11075	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BM525_11080	ENOG4105BZU	Histidine kinase
BM525_11095	ENOG4105C8P	)-transporter
BM525_11100	ENOG4105DHP	deoxycytidine triphosphate deaminase
BM525_11105	ENOG4105D1F	ATP-binding protein
BM525_11110	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BM525_11120	ENOG4105D1A	Methyltransferase
BM525_11125	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BM525_11130	ENOG4105E9H	Lytic Murein transglycosylase
BM525_11150	ENOG4105C8N	cysteinyl-tRNA synthetase
BM525_11155	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BM525_11160	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
BM525_11170	ENOG4107S78	Band 7 protein
BM525_11185	ENOG4105KVH	Transcriptional regulator
BM525_11200	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
BM525_11210	ENOG4105CIS	alcohol dehydrogenase
BM525_11240	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
BM525_11250	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
BM525_11255	ENOG4105E96	Colicin v production protein
BM525_11260	ENOG4108S3P	Sporulation domain protein
BM525_11265	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BM525_11270	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BM525_11285	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
BM525_11290	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
BM525_11295	ENOG4105MP9	class II Aldolase
BM525_11310	ENOG4105YAJ	CopG Arc MetJ
BM525_11315	ENOG4105ETT	transcriptional Regulator, LysR family
BM525_11335	ENOG4108XHQ	(2Fe-2S)-binding domain protein
BM525_11355	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BM525_11370	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
BM525_11405	ENOG4108Z6Z	Transcriptional regulator
BM525_11410	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
BM525_11435	ENOG4105DKW	ABC transporter
BM525_11440	ENOG4105CRW	Short chain fatty acid transporter
BM525_11445	ENOG4105BZU	Histidine kinase
BM525_11470	ENOG4108BPE	-transporting atpase
BM525_11495	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BM525_11520	ENOG4105D8T	Acyltransferase
BM525_11530	ENOG4108UH6	UPF0754 membrane protein
BM525_11555	ENOG4105CUG	Oligopeptidase b
BM525_11560	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
BM525_11565	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
BM525_11570	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
BM525_11575	ENOG4108428	Inherit from COG: -acetyltransferase
BM525_11585	ENOG4108ZZ3	UPF0260 protein
BM525_11590	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
BM525_11600	ENOG4105VNG	YcgL domain-containing protein
BM525_11605	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
BM525_11610	ENOG4105CEY	Amp-dependent synthetase and ligase
BM525_11615	ENOG410832A	alpha/beta hydrolase fold
BM525_11630	ENOG41072GX	Peptidase M22 Glycoprotease
BM525_11635	ENOG4105DVT	helicase
BM525_11685	ENOG4107T8T	UPF0173 metal-dependent hydrolase
BM525_11690	ENOG4105D05	Receptor
BM525_11700	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
BM525_11705	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BM525_11710	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BM525_11715	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BM525_11720	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
BM525_11725	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BM525_11730	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
BM525_11735	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
BM525_11740	ENOG4105S64	Formate nitrite transporter
BM525_11745	ENOG4108NVR	Methyl-accepting chemotaxis
BM525_11775	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BM525_11780	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
BM525_11785	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
BM525_11795	ENOG4105BZU	Histidine kinase
BM525_11865	ENOG4107R08	Integrase
BM525_11880	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BM525_11885	ENOG4107QMP	dna polymerase iii subunits gamma and tau
BM525_11890	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BM525_11900	ENOG4105E18	UPF0276 protein
BM525_11910	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BM525_11950	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
BM525_11970	ENOG4105CXG	d-lactate dehydrogenase
BM525_11975	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BM525_11980	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
BM525_11985	ENOG4105C34	Pseudouridine synthase
BM525_11990	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM525_12000	ENOG4105K6V	RNA polymerase
BM525_12015	ENOG4105EMU	Dehydrogenase
BM525_12030	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
BM525_12035	ENOG4106VK6	Flagellar motor protein
BM525_12040	ENOG4105E14	MotA TolQ exbB proton channel
BM525_12050	ENOG4105CTB	Polyprenyl synthetase
BM525_12055	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BM525_12060	ENOG4108ZAI	phosphatidylglycerophosphatase a
BM525_12065	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
BM525_12070	ENOG4107YIM	Involved in the transcription termination process (By similarity)
BM525_12075	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
BM525_12090	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
BM525_12095	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
BM525_12100	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BM525_12105	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BM525_12110	ENOG4105C5H	ABC transporter
BM525_12120	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
BM525_12130	ENOG4105EAC	phosphoserine phosphatase
BM525_12140	ENOG4105EYA	deoxyribonuclease
BM525_12145	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
BM525_12150	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BM525_12155	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BM525_12160	ENOG4105C3F	Signal peptidase i
BM525_12165	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
BM525_12185	ENOG4105EMN	RNA polymerase sigma factor
BM525_12190	ENOG4108IYU	L-aspartate oxidase
BM525_12205	ENOG4105Y75	tpr repeat protein
BM525_12210	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
BM525_12215	ENOG4108YZY	peptidylprolyl cis-trans isomerase
BM525_12220	ENOG4108YZA	Nitrogen regulatory protein pii
BM525_12225	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
BM525_12285	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
BM525_12290	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
BM525_12295	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BM525_12300	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BM525_12305	ENOG4105DTN	riboflavin biosynthesis protein ribF
BM525_12310	ENOG4105CJR	Integral membrane protein (MviN
BM525_12315	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
BM525_12330	ENOG4105CHR	reductase
BM525_12335	ENOG4105C09	Bile acid
BM525_12340	ENOG4108PTX	LysR family Transcriptional regulator
BM525_12360	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BM525_12365	ENOG4105EIN	peptidylprolyl cis-trans isomerase
BM525_12370	ENOG4105K70	DNA-binding protein
BM525_12375	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
BM525_12380	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BM525_12385	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BM525_12390	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BM525_12435	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BM525_12445	ENOG4108R96	Methyltransferase, YaeB family
BM525_12450	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BM525_12455	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BM525_12460	ENOG4105HDD	phospholipase
BM525_12465	ENOG4105DGU	Histone deacetylase
BM525_12470	ENOG4105C8Q	Methyl-accepting chemotaxis
BM525_12475	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BM525_12480	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BM525_12485	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BM525_12500	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BM525_12505	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BM525_12510	ENOG4105N21	Membrane
BM525_12515	ENOG4105CUT	histidyl-tRNA synthetase
BM525_12520	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BM525_12535	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BM525_12540	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BM525_12545	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
BM525_12555	ENOG4108Z4V	iron-sulfur cluster assembly
BM525_12560	ENOG4105C9B	Cysteine desulfurase
BM525_12565	ENOG4105JRK	feS assembly protein SufD
BM525_12570	ENOG4105C3K	feS assembly ATPase SufC
BM525_12580	ENOG4105C3J	Cysteine desulfurase
BM525_12585	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
BM525_12590	ENOG4105CT3	Monooxygenase
BM525_12595	ENOG4105D7W	serine acetyltransferase
BM525_12600	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
BM525_12620	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BM525_12625	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BM525_12630	ENOG4105VIE	preprotein translocase, subunit YajC
BM525_12635	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BM525_12640	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
BM525_12655	ENOG4108P9J	Phage shock protein A
BM525_12680	ENOG4106032	Glutathionylspermidine synthase
BM525_12695	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BM525_12710	ENOG4105CSV	Glutaminase
BM525_12715	ENOG4105G6Z	alkaline phosphatase
BM525_12725	ENOG4107RET	Isocitrate lyase
BM525_12750	ENOG4105C0H	protease
BM525_12785	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
BM525_12805	ENOG4105CPK	Glycosyl transferase (Group 1
BM525_12820	ENOG4105CAQ	asparagine synthetase
BM525_12825	ENOG4105EXC	Acyl-transferase
BM525_12830	ENOG4108PQP	glycosyl transferase group 1
BM525_12900	ENOG4105D3Q	Sugar transferase
BM525_12915	ENOG4108QV3	biosynthesis protein
BM525_12930	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
BM525_12950	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
BM525_12960	ENOG4105D1S	lipid A biosynthesis
BM525_12975	ENOG4107QPN	acyl-Coa dehydrogenase
BM525_12990	ENOG4105BZU	Histidine kinase
BM525_12995	ENOG4107104	thymidine kinase
BM525_13010	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BM525_13040	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
BM525_13045	ENOG4108RWN	rrna methyltransferase
BM525_13050	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BM525_13065	ENOG4105C26	Dehydrogenase
BM525_13070	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
BM525_13085	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
BM525_13090	ENOG4108Z4X	TRANSCRIPTIONal
BM525_13120	ENOG4105CSU	acyl-Coa dehydrogenase
BM525_13140	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
BM525_13145	ENOG4105E0F	Histidine kinase
BM525_13155	ENOG4105NA0	Transcriptional regulator
BM525_13160	ENOG410822N	TonB family
BM525_13175	ENOG4107XDR	Lactoylglutathione lyase
BM525_13190	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
BM525_13195	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
BM525_13200	ENOG4105C7W	Xanthine dehydrogenase
BM525_13220	ENOG4105CHR	reductase
BM525_13225	ENOG4105EMU	Dehydrogenase
BM525_13230	ENOG4107RKG	DJ-1/PfpI family
BM525_13235	ENOG4107U9T	Pfam:Ribonuclease_BN
BM525_13250	ENOG4108VWS	Yaeq family
BM525_13280	ENOG4105S8Q	sugar efflux transporter
BM525_13300	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BM525_13320	ENOG4105BZU	Histidine kinase
BM525_13325	ENOG4105BZU	Histidine kinase
BM525_13340	ENOG4105BZU	Histidine kinase
BM525_13390	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BM525_13395	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BM525_13400	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BM525_13405	ENOG4105CE4	GlcNAc 6-P deacetylase
BM525_13410	ENOG4105RD7	BadF BadG BcrA BcrD
BM525_13420	ENOG4105DAA	L-lactate
BM525_13445	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
BM525_13450	ENOG4105D0A	hydroxylase
BM525_13455	ENOG4107RAQ	aminopeptidase
BM525_13470	ENOG4108RVA	ribokinase
BM525_13485	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
BM525_13490	ENOG4105E66	phosphoriboisomerase A
BM525_13495	ENOG4108JQ1	Dehydrogenase
BM525_13515	ENOG4105XZD	Fe-S protein
BM525_13550	ENOG4107QN2	dihydrolipoyl dehydrogenase
BM525_13555	ENOG4107QSN	dihydrolipoamide acetyltransferase
BM525_13560	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
BM525_13565	ENOG41073TP	transcriptional regulator
BM525_13575	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
BM525_13580	ENOG4108WIW	Aspartyl protease
BM525_13585	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
BM525_13590	ENOG4108ZUW	Major pilin subunit
BM525_13595	ENOG4105D7Q	type ii secretion system
BM525_13600	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
BM525_13610	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
BM525_13615	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
BM525_13620	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
BM525_13630	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BM525_13635	ENOG4105DR5	peptidase
BM525_13640	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BM525_13645	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BM525_13650	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
BM525_13655	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
BM525_13660	ENOG4105CPF	Cell wall formation (By similarity)
BM525_13665	ENOG4105DFU	Cell wall formation (By similarity)
BM525_13670	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BM525_13675	ENOG4105CNI	cell division protein FtsW
BM525_13680	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BM525_13685	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BM525_13690	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
BM525_13695	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
BM525_13700	ENOG4105CJN	penicillin-binding protein
BM525_13705	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
BM525_13710	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BM525_13715	ENOG4108V6E	Cell division protein mraZ
BM525_13740	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
BM525_13760	ENOG4105EHV	domain protein
BM525_13775	ENOG4105BZU	Histidine kinase
BM525_13785	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM525_13790	ENOG4105BZU	Histidine kinase
BM525_13800	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BM525_13805	ENOG4105DPW	Major facilitator superfamily MFS_1
BM525_13835	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
BM525_13840	ENOG4105D7Z	glutathione synthase
BM525_13845	ENOG4108UJU	UPF0301 protein
BM525_13850	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BM525_13860	ENOG4105CZX	twitching motility protein
BM525_13865	ENOG4105CZX	twitching motility protein
BM525_13870	ENOG4105DFA	alanine racemase domain protein
BM525_13875	ENOG4105II7	pyrroline-5-carboxylate reductase
BM525_13880	ENOG4108VIA	integral membrane protein
BM525_13890	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BM525_13905	ENOG4108SHQ	Glutathione S-transferase
BM525_13910	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BM525_13915	ENOG4108Z9K	Osmotically inducible protein
BM525_13920	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BM525_13935	ENOG4108UMN	azlc family
BM525_13945	ENOG4105F27	Major Facilitator
BM525_13950	ENOG4105VFU	Rna-binding protein
BM525_13955	ENOG4105D1Q	UPF0246 protein
BM525_13965	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
BM525_13970	ENOG4107QP8	phosphohexose isomerase
BM525_13975	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BM525_13980	ENOG4105D98	threonine synthase
BM525_13985	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
BM525_14000	ENOG4105CC0	LysR family Transcriptional regulator
BM525_14015	ENOG41082YX	Transcriptional regulator, arsr family
BM525_14025	ENOG4105CAU	Arsenical resistance protein, ArsH
BM525_14030	ENOG4105D6J	arsenicaL-resistance protein
BM525_14035	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BM525_14040	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
BM525_14050	ENOG4105BZU	Histidine kinase
BM525_14065	ENOG4105K6H	D-cysteine desulfhydrase
BM525_14095	ENOG4105E3Q	saccharopine dehydrogenase
BM525_14110	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
BM525_14115	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
BM525_14120	ENOG41082RQ	UPF0102 protein
BM525_14130	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
BM525_14135	ENOG4105W4M	Transport-associated protein
BM525_14155	ENOG4105BZU	Histidine kinase
BM525_14185	ENOG4105CR4	methylisocitrate lyase
BM525_14190	ENOG4105BZN	citrate synthase
BM525_14195	ENOG4108I0Z	Aconitate hydratase
BM525_14200	ENOG4105C7F	AcnD-accessory protein PrpF
BM525_14205	ENOG4105BZU	Histidine kinase
BM525_14225	ENOG4105BZU	Histidine kinase
BM525_14230	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
BM525_14235	ENOG4105CBC	glutamate synthase
BM525_14240	ENOG4105BZ8	glutamate synthase
BM525_14260	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BM525_14265	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
BM525_14270	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
BM525_14275	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
BM525_14290	ENOG4105CJP	fad dependent oxidoreductase
BM525_14295	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
BM525_14300	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BM525_14305	ENOG4108K5P	(LipO)protein
BM525_14310	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
BM525_14315	ENOG4105EDR	glucose galactose transporter
BM525_14345	ENOG4108U78	Glutathione S-transferase
BM525_14350	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
BM525_14360	ENOG4105CSR	polyphosphate kinase 2
BM525_14365	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
BM525_14370	ENOG4107QMS	site-determining protein
BM525_14375	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
BM525_14380	ENOG4105C9Q	fumarate hydratase class II
BM525_14420	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
BM525_14425	ENOG4105CHM	Aminotransferase
BM525_14435	ENOG4105CI3	gtp-binding protein typa
BM525_14440	ENOG4105C5F	glutamine synthetase
BM525_14450	ENOG4105CUX	Signal transduction histidine kinase
BM525_14455	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM525_14460	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BM525_14465	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
BM525_14470	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
BM525_14480	ENOG4105BZU	Histidine kinase
BM525_14500	ENOG4105BZU	Histidine kinase
BM525_14505	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BM525_14510	ENOG4105MYG	DNA polymerase iii, chi subunit
BM525_14515	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BM525_14520	ENOG4108M8S	permease YjgP YjgQ family protein
BM525_14525	ENOG4108K5H	permease YjgP YjgQ family protein
BM525_14540	ENOG4105K6V	RNA polymerase
BM525_14600	ENOG4105E2V	Glycosyltransferase 36
BM525_14610	ENOG410620I	Diguanylate cyclase
BM525_14645	ENOG4105BZU	Histidine kinase
BM525_14665	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
BM525_14670	ENOG4105EHG	Permease protein
BM525_14675	ENOG4107R4I	Periplasmic binding protein
BM525_14685	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BM525_14695	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
BM525_14700	ENOG4105EMK	carboxylate amino acid amine transporter
BM525_14720	ENOG4107RF2	cellulose-binding family II protein
BM525_14730	ENOG4105CY0	Metallo-Beta-Lactamase
BM525_14740	ENOG4105DC7	peptidase M24
BM525_14745	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
BM525_14750	ENOG4105BZU	Histidine kinase
BM525_14755	ENOG4108N2Y	auxin Efflux
BM525_14760	ENOG4105EY3	heparinase II III family protein
BM525_14765	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
BM525_14770	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BM525_14775	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
BM525_14795	ENOG41088PD	hydrolase
BM525_14805	ENOG4105DZG	Dehydrogenase
BM525_14825	ENOG4105CJ1	ABC, transporter
BM525_14835	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BM525_14840	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
BM525_14850	ENOG4105WF7	pyrroloquinoline quinone biosynthesis protein d
BM525_14855	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
BM525_14885	ENOG4105BZU	Histidine kinase
BM525_14905	ENOG4105WH1	Two component transcriptional regulator luxr family
BM525_14910	ENOG4105BZU	Histidine kinase
BM525_14915	ENOG4105JQN	Transcriptional regulator
BM525_14920	ENOG4105C26	Dehydrogenase
BM525_14925	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BM525_14940	ENOG4105C94	Transporter
BM525_14945	ENOG4105CXG	d-lactate dehydrogenase
BM525_14950	ENOG41086KC	Transcriptional regulator
BM525_14955	ENOG4105P8Q	Curli production assembly transport component CsgG
BM525_14985	ENOG4105WH1	Two component transcriptional regulator luxr family
BM525_15010	ENOG4105C1J	atp-dependent rna helicase
BM525_15025	ENOG4108UHU	Aldolase
BM525_15030	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
BM525_15045	ENOG4105EGS	Mechanosensitive ion channel
BM525_15055	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
BM525_15085	ENOG4105HF0	Membrane
BM525_15090	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BM525_15105	ENOG4105BZU	Histidine kinase
BM525_15115	ENOG4105CQ2	DNA polymerase
BM525_15125	ENOG4105CEY	Amp-dependent synthetase and ligase
BM525_15160	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
BM525_15165	ENOG4105EJ2	Transcriptional regulator
BM525_15175	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
BM525_15185	ENOG4108RG0	uracil-dna glycosylase
BM525_15190	ENOG4105BZU	Histidine kinase
BM525_15200	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
BM525_15205	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
BM525_15230	ENOG4105FM1	phage shock protein C
BM525_15235	ENOG41087YS	Phage shock protein A
BM525_15245	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BM525_15265	ENOG4105EDQ	levansucrase EC 2.4.1.10
BM525_15270	ENOG4108HKT	sucrose-6-phosphate hydrolase
BM525_15295	ENOG4105CPK	Glycosyl transferase (Group 1
BM525_15325	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
BM525_15330	ENOG4105BZU	Histidine kinase
BM525_15335	ENOG4105C4W	S-formylglutathione hydrolase
BM525_15340	ENOG4106HNH	Acyl-transferase
BM525_15345	ENOG4106HNH	Acyl-transferase
BM525_15350	ENOG4105CUY	Mechanosensitive ion channel
BM525_15365	ENOG4108535	NAD dependent epimerase/dehydratase family
BM525_15370	ENOG4105C8J	)-transporter
BM525_15385	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BM525_15400	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
BM525_15410	ENOG4109015	Biopolymer transport protein exbD tolR
BM525_15420	ENOG4105EJG	cellulose synthase
BM525_15425	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
BM525_15435	ENOG4107QZ7	Cellulose synthase catalytic subunit
BM525_15450	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
BM525_15455	ENOG4105K4T	epimerase
BM525_15465	ENOG4105KWG	Pfam:DUF1696
BM525_15470	ENOG4105BZU	Histidine kinase
BM525_15480	ENOG4105EFZ	amidohydrolase
BM525_15490	ENOG4105C5X	domain protein
BM525_15500	ENOG4108WAV	Transcriptional regulator
BM525_15505	ENOG4105E7A	Glutamine amidotransferase
BM525_15515	ENOG4108Z12	YiaAB two helix domain-containing protein
BM525_15535	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
BM525_15545	ENOG4105C26	Dehydrogenase
BM525_15550	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
BM525_15555	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
BM525_15560	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
BM525_15570	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
BM525_15575	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
BM525_15580	ENOG4108R86	Transcriptional regulator
BM525_15595	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
BM525_15605	ENOG4105E53	ec 3.2.1.28
BM525_15610	ENOG4105C6Z	Gluconate
BM525_15615	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BM525_15620	ENOG4105K2J	Transcriptional regulator
BM525_15625	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BM525_15635	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BM525_15655	ENOG4105CJ2	(LipO)protein
BM525_15660	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
BM525_15665	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BM525_15670	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BM525_15675	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BM525_15680	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BM525_15685	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BM525_15690	ENOG4105RKW	reductase (By
BM525_15695	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BM525_15700	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
BM525_15715	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BM525_15720	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
BM525_15745	ENOG4105DBI	uridine monophosphokinase
BM525_15750	ENOG4105D9N	nucleoside
BM525_15770	ENOG4105BZU	Histidine kinase
BM525_15775	ENOG4107S1V	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
BM525_15785	ENOG4107QN1	sodium solute
BM525_15795	ENOG4105BZU	Histidine kinase
BM525_15805	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
BM525_15815	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
BM525_15830	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BM525_15845	ENOG4105CPC	Aldo Keto reductase
BM525_15870	ENOG4105D9P	serine threonine protein kinase
BM525_15920	ENOG4105CH6	catalase
BM525_15960	ENOG4108JJA	ABC, transporter
BM525_15965	ENOG41063Z6	transcriptional regulator, lysR family
BM525_16005	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
BM525_16010	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
BM525_16015	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
BM525_16030	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BM525_16070	ENOG4105K64	Glycosyl transferase, family 2
BM525_16090	ENOG4105F0R	Cytidylyltransferase
BM525_16095	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BM525_16100	ENOG4105C5E	polysaccharide biosynthesis protein
BM525_16120	ENOG4108ZT0	50S ribosomal protein l17
BM525_16125	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BM525_16130	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BM525_16135	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BM525_16140	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BM525_16145	ENOG41067V7	50S ribosomal protein L36
BM525_16150	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BM525_16155	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BM525_16160	ENOG4105VPB	50S ribosomal protein L30
BM525_16165	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BM525_16170	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BM525_16175	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BM525_16180	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BM525_16185	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BM525_16190	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BM525_16195	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BM525_16200	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BM525_16205	ENOG4105BZU	Histidine kinase
BM525_16215	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BM525_16220	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BM525_16225	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BM525_16260	ENOG4108UV7	flagellar protein motX
BM525_16270	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
BM525_16275	ENOG4107QK7	reductase
BM525_16285	ENOG4107VAM	peptidase, m28
BM525_16295	ENOG4105BZU	Histidine kinase
BM525_16315	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BM525_16320	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BM525_16325	ENOG4108XM1	transcriptional regulator AsnC family
BM525_16335	ENOG4105VEQ	Cold shock protein
BM525_16340	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
BM525_16360	ENOG4105DGW	oligopeptidase A
BM525_16365	ENOG4107YTP	response regulator receiver protein
BM525_16375	ENOG4105BZU	Histidine kinase
BM525_16380	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM525_16385	ENOG4105DC8	reductase
BM525_16390	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
BM525_16395	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BM525_16440	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
BM525_16445	ENOG4108JJA	ABC, transporter
BM525_16450	ENOG4105WH1	Two component transcriptional regulator luxr family
BM525_16475	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
BM525_16480	ENOG4108HKT	sucrose-6-phosphate hydrolase
BM525_16495	ENOG4105C27	TonB-dependent Receptor Plug
BM525_16500	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
BM525_16505	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
BM525_16510	ENOG4105VEQ	Cold shock protein
BM525_16515	ENOG41063M6	Cell Division Protein
BM525_16520	ENOG4105C25	Primosomal protein n'
BM525_16525	ENOG4105VFB	Binds the 23S rRNA (By similarity)
BM525_16535	ENOG4105C6K	Malic enzyme
BM525_16540	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
BM525_16545	ENOG4105SYT	Methylenetetrahydrofolate reductase
BM525_16550	ENOG4107S2Z	UPF0761 membrane protein
BM525_16570	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
BM525_16575	ENOG4105SUU	thioesterase domain
BM525_16580	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM525_16585	ENOG4105D58	Diguanylate phosphodiesterase
BM525_16590	ENOG4105D58	Diguanylate phosphodiesterase
BM525_16595	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
BM525_16600	ENOG4105CAK	Cell division ATP-binding protein ftsE
BM525_16605	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BM525_16610	ENOG4106H78	methyltransferase
BM525_16620	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
BM525_16635	ENOG4105PW4	Sugar fermentation stimulation protein homolog
BM525_16640	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BM525_16645	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
BM525_16650	ENOG4105DJ0	Poly(A) Polymerase
BM525_16655	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BM525_16660	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
BM525_16665	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
BM525_16670	ENOG4105DY8	decarboxylase
BM525_16685	ENOG4105E3A	(ABC) transporter
BM525_16690	ENOG4105DA5	(ABC) transporter
BM525_16695	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
BM525_16700	ENOG4105EB3	Histidine kinase
BM525_16705	ENOG4108ESX	Receptor
BM525_16710	ENOG4107E2E	PKHD-type hydroxylase
BM525_16740	ENOG4105D22	carbon starvation protein
BM525_16765	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BM525_16770	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BM525_16775	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BM525_16780	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BM525_16785	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BM525_16790	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BM525_16795	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BM525_16800	ENOG4108VZM	50s ribosomal protein L10
BM525_16805	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BM525_16810	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BM525_16830	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BM525_16835	ENOG4105PM1	preprotein translocase subunit SecE
BM525_16845	ENOG4105BZ1	(ABC) transporter
BM525_16850	ENOG4105JSC	dimethylmenaquinone methyltransferase
BM525_16855	ENOG4105C9K	Endothelin-converting enzyme 1
BM525_16865	ENOG4105C1J	atp-dependent rna helicase
BM525_16870	ENOG4105EKE	dihydroorotase
BM525_16875	ENOG4105QNF	Outer membrane lipoprotein
BM525_16880	ENOG4107RGM	aldo keto reductase
BM525_16885	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
BM525_16895	ENOG4105DP8	Major facilitator superfamily MFS_1
BM525_16900	ENOG4107QW3	Sucrose phosphorylase
BM525_16910	ENOG4105EUJ	GTP cyclohydrolase i
BM525_16915	ENOG410642E	Short chain dehydrogenase
BM525_16920	ENOG4105DWY	Agmatine deiminase
BM525_16935	ENOG4107QRT	dEAD DEAH box helicase
BM525_16945	ENOG4107T0X	DNA ligase
BM525_16950	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BM525_16955	ENOG4105D7K	pfkb domain protein
BM525_16970	ENOG4105CYM	Glutathione S-transferase
BM525_16985	ENOG4107IFA	Lipase (EC 3.1.1.3)
BM525_16990	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
BM525_17015	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
BM525_17020	ENOG4105CFC	Transporter
BM525_17025	ENOG4105EPW	hflc protein
BM525_17030	ENOG4107QJR	hflk protein
BM525_17035	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BM525_17040	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
BM525_17045	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BM525_17050	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BM525_17055	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BM525_17060	ENOG4105K8N	protein family UPF0079, ATPase
BM525_17065	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BM525_17070	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
BM525_17080	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
BM525_17090	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
BM525_17095	ENOG4105MYN	Zinc uptake regulation protein
BM525_17105	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
BM525_17110	ENOG4105CDV	Ompa motb domain protein
BM525_17115	ENOG4105CDU	Replicative dna helicase
BM525_17140	ENOG4108RPX	mosc domain containing protein
BM525_17160	ENOG410804D	Sensor Signal Transduction Histidine Kinase
BM525_17185	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
BM525_17190	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BM525_17195	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
BM525_17200	ENOG4105BZU	Histidine kinase
BM525_17210	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BM525_17220	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
BM525_17225	ENOG4105BZU	Histidine kinase
BM525_17230	ENOG4105C8Q	Methyl-accepting chemotaxis
BM525_17250	ENOG4106IBS	oxygenase
BM525_17260	ENOG4105FDP	GntR family transcriptional regulator
BM525_17270	ENOG4105CJQ	hydrolase, family 31
BM525_17275	ENOG4107RUZ	Sss sodium solute transporter superfamily
BM525_17280	ENOG4107ZSV	Receptor
BM525_17285	ENOG4105PGM	cation diffusion facilitator family transporter
BM525_17300	ENOG4105DFD	Na H antiporter
BM525_17320	ENOG41060NJ	transcriptional regulator
BM525_17325	ENOG4107QNK	)-transporter
BM525_17330	ENOG4108JJ8	(ABC) transporter
BM525_17335	ENOG4108JJ9	ABC, transporter
BM525_17345	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BM525_17350	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BM525_17385	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
BM525_17395	ENOG4105D05	Receptor
BM525_17410	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
BM525_17425	ENOG4105Q26	Siderophore-interacting protein
BM525_17430	ENOG4105VDW	Csbd family
BM525_17445	ENOG4105EMN	RNA polymerase sigma factor
BM525_17450	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BM525_17470	ENOG4108YZN	class I peptide chain release factor
BM525_17475	ENOG4107TTQ	Alpha beta hydrolase fold
BM525_17495	ENOG4105DS1	cytochrome b561
BM525_17505	ENOG4105CEP	NADH dehydrogenase
BM525_17520	ENOG4105CR8	Transcriptional regulator
BM525_17525	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
BM525_17530	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
BM525_17540	ENOG4105BZU	Histidine kinase
BM525_17550	ENOG4105DEN	Luciferase family
BM525_17555	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BM525_17560	ENOG4105E98	transcriptional regulator DeoR family
BM525_17565	ENOG4105D9R	oxidoreductase
BM525_17570	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BM525_17580	ENOG4108Q5Y	Membrane
BM525_17585	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BM525_17590	ENOG4105D03	DNA-3-methyladenine glycosylase II
BM525_17595	ENOG41066YJ	Beta-lactamase
BM525_17600	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
BM525_17610	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BM525_17615	ENOG4105W8H	transhydrogenase (subunit alpha
BM525_17620	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BM525_17670	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
BM525_17705	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BM525_17720	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BM525_17725	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BM525_17730	ENOG4105FS0	cytoplasmic membrane protein
BM525_17735	ENOG4105VF7	tolerance protein
BM525_17740	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
BM525_17745	ENOG4105DR5	peptidase
BM525_17750	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BM525_17755	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
BM525_17760	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BM525_17800	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BM525_17810	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BM525_17815	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BM525_17820	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
BM525_17825	ENOG4105DC1	bifunctional purine biosynthesis protein purh
BM525_17835	ENOG4105C12	Phosphoribosylglycinamide synthetase
BM525_17855	ENOG4105EYW	Ion transport protein
BM525_17860	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
BM525_17870	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BM525_17875	ENOG4105E0F	Histidine kinase
BM525_17885	ENOG4105CJQ	hydrolase, family 31
BM525_17960	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
BM525_17965	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BM525_17970	ENOG4105VEJ	Heat shock protein
BM525_17975	ENOG4108XKW	General secretion pathway protein C
BM525_17985	ENOG4107QHF	type ii secretion system protein e
BM525_17990	ENOG4105D7Q	type ii secretion system
BM525_17995	ENOG4108VAU	general secretion pathway protein G
BM525_18000	ENOG4105VWV	general secretion pathway protein h
BM525_18040	ENOG4105C26	Dehydrogenase
BM525_18050	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
BM525_18055	ENOG4107RK2	ADP-ribose diphosphatase NudE
BM525_18070	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
BM525_18075	ENOG4105DJ9	glucan biosynthesis protein
BM525_18085	ENOG4105YP7	UPF0270 protein
BM525_18090	ENOG4105DNZ	Alpha Beta Hydrolase
BM525_18100	ENOG4105C5H	ABC transporter
BM525_18125	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BM525_18135	ENOG4108RRZ	Transcription elongation factor GreB
BM525_18140	ENOG4105BZM	domain protein
BM525_18160	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
BM525_18165	ENOG4105MJ2	Competence protein
BM525_18175	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
BM525_18200	ENOG4107R73	Mate efflux family protein
BM525_18205	ENOG4107BJW	polysaccharide deacetylase
BM525_18215	ENOG4108ZX6	Electron transport protein SCO1 SenC
BM525_18220	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
BM525_18225	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
BM525_18245	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
BM525_18250	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
BM525_18255	ENOG4105BZ9	Cytochrome C oxidase, subunit I
BM525_18265	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BM525_18270	ENOG4105E55	glycerol-3-phosphate acyltransferase
BM525_18275	ENOG4105C7B	Threonine dehydratase
BM525_18280	ENOG4105C01	Dihydroxy-acid dehydratase
BM525_18285	ENOG4105EN6	Membrane
BM525_18290	ENOG4105C0P	Mg chelatase subunit ChlI
BM525_18295	ENOG4105EMY	transcriptional regulator
BM525_18300	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
BM525_18305	ENOG4105C2C	drug resistance transporter, Bcr CflA
BM525_18310	ENOG4105V1F	Fermentation respiration switch protein
BM525_18315	ENOG4105CFU	surface antigen
BM525_18320	ENOG4105MA0	exported protein
BM525_18345	ENOG4105C5I	Dehydrogenase
BM525_18355	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
BM525_18400	ENOG4105CI2	imidazolone-5-propionate hydrolase
BM525_18425	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
BM525_18430	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BM525_18435	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
BM525_18440	ENOG4105DSJ	YicC domain protein
BM525_18445	ENOG4105QV4	Tryptophan halogenase
BM525_18465	ENOG4105CT4	transporter
BM525_18470	ENOG41060NJ	transcriptional regulator
BM525_18480	ENOG4105CDV	Ompa motb domain protein
BM525_18485	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BM525_18500	ENOG4108K3A	Glutathione S-transferase
BM525_18510	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BM525_18515	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BM525_18520	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BM525_18525	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BM525_18530	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BM525_18535	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BM525_18540	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BM525_18545	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
BM525_18555	ENOG4105FA0	parb-like partition protein
BM525_18560	ENOG4107QJE	Chromosome Partitioning Protein
BM525_18565	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BM525_18570	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BM525_18585	ENOG4105QTB	Flavodoxin
BM525_18590	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BM525_18595	ENOG4108VPT	UPF0234 protein
BM525_18600	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BM525_18605	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
BM525_18635	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BM525_18755	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM525_18820	ENOG4107QHF	type ii secretion system protein e
BM525_18850	ENOG4107QHF	type ii secretion system protein e
BM525_19355	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
BM525_19445	ENOG4105EXC	Acyl-transferase
BM525_19565	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
BM525_19855	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
BM525_19860	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
BM525_19935	ENOG4105CDV	Ompa motb domain protein
BM525_19960	ENOG4107QUV	Domain protein
BM525_19970	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BM525_20015	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
BM525_20065	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BM525_20095	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM525_20115	ENOG4105C3J	Cysteine desulfurase
BM525_20120	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BM525_20145	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
BM525_20180	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BM525_20185	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BM525_20190	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BM525_20245	ENOG4105DZR	Type I site-specific deoxyribonuclease
BM525_20285	ENOG4107RRE	RNA-directed DNA polymerase
BM525_20295	ENOG4105C7H	Helicase, RecD TraA family
BM525_20320	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM525_20335	ENOG4105C0B	DNA polymerase III (alpha subunit)
BM525_20365	ENOG4105BZU	Histidine kinase
BM525_20385	ENOG4105D7V	transposase
BM525_20390	ENOG4105C4R	Atp-dependent dna helicase
BM525_20410	ENOG4107XMK	single-stranded DNA-binding protein
BM525_20440	ENOG4105K70	DNA-binding protein
BM525_20675	ENOG4105ECI	YeeC-like protein
BM525_20680	ENOG4105F6A	helicase
BM525_20685	ENOG4105D85	methylase
BM525_20695	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BM525_20740	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BM525_20780	ENOG4105C2M	dna polymerase I
BM525_20825	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BM525_20850	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
BM525_20905	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BM525_20945	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BM525_20950	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BM525_20965	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BM525_20970	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BM525_21020	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
BM525_21140	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BM525_21215	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BM525_21220	ENOG4105D58	Diguanylate phosphodiesterase
BM525_21225	ENOG4108IAB	Phoh family
BM525_21240	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BM525_21245	ENOG4108IJ1	Dehydrogenase
BM525_21255	ENOG4105CMR	udp-glucose 4-epimerase
BM525_21315	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BM525_21320	ENOG4105BZU	Histidine kinase
BM525_21330	ENOG4105CAQ	asparagine synthetase
BM525_21340	ENOG4107QJE	Chromosome Partitioning Protein
BM525_21345	ENOG4105FA0	parb-like partition protein
BM525_21360	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BM525_21365	ENOG4108QV3	biosynthesis protein
BM525_21395	ENOG4105CAQ	asparagine synthetase
BM525_21405	ENOG4105PSV	Polysaccharide Biosynthesis Protein
BM525_21415	ENOG4107QUV	Domain protein
BM525_21440	ENOG4105CJB	Exodeoxyribonuclease I
BM525_21500	ENOG4105BZU	Histidine kinase
BM525_21525	ENOG4105C7H	Helicase, RecD TraA family
BM525_21560	ENOG4105C3F	Signal peptidase i
BM525_21600	ENOG4108Z33	Thiol disulfide Interchange Protein