locus-tag	class	description
MADE_000001020715	ENOG4105DIJ	Phosphoethanolamine transferase
MADE_000001020755	ENOG4105E27	serine threonine protein kinase
MADE_000001020780	ENOG4105C8Q	Methyl-accepting chemotaxis
MADE_000001020785	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
MADE_000001020790	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
MADE_000001020805	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
MADE_000001020810	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
MADE_000001020840	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
MADE_000001020845	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
MADE_000001020920	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
MADE_000001020935	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
MADE_000001020950	ENOG4105BZU	Histidine kinase
MADE_000001020960	ENOG4108BY2	phosphohistidine phosphatase
MADE_000001020975	ENOG4106KVJ	cytochrome C assembly protein
MADE_000001020980	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MADE_000001021030	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
MADE_000001021035	ENOG4105BZ1	(ABC) transporter
MADE_000001021050	ENOG4105K5M	30s ribosomal protein S16
MADE_000001021055	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
MADE_000001021060	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
MADE_000001021065	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
MADE_000001021070	ENOG4105EN6	Membrane
MADE_000001021075	ENOG4105E39	Enoyl-CoA hydratase
MADE_000001021080	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
MADE_000001021100	ENOG4108ZJT	translation initiation factor, Sui1
MADE_000001021110	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
MADE_000001021120	ENOG4105BZU	Histidine kinase
MADE_000001021130	ENOG4107WP9	Histidine kinase
MADE_000001021140	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
MADE_000001021145	ENOG4105I03	Flagellin
MADE_000001021160	ENOG4105C9M	aspartyl-trna synthetase
MADE_000001021165	ENOG4108TIT	dATP pyrophosphohydrolase
MADE_000001021170	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
MADE_000001021175	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
MADE_000001021180	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
MADE_000001021190	ENOG4107YD3	Thioesterase
MADE_000001021195	ENOG4105E02	MotA TolQ exbB proton channel
MADE_000001021200	ENOG4105M8F	Biopolymer transport protein exbD tolR
MADE_000001021210	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
MADE_000001021230	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
MADE_000001021245	ENOG4108NRW	Phospholipase, patatin family
MADE_000001021250	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
MADE_000001021280	ENOG4105DS1	cytochrome b561
MADE_000001021285	ENOG4105BZU	Histidine kinase
MADE_000001021300	ENOG4105EJC	lysr family transcriptional regulator
MADE_000001021305	ENOG4108VKG	metal-dependent hydrolase
MADE_000001021315	ENOG4105BZS	acriflavin resistance protein
MADE_000001021325	ENOG4108XG4	DNA-binding transcriptional regulator
MADE_000001021330	ENOG4108ESX	Receptor
MADE_000001021350	ENOG4105BZU	Histidine kinase
MADE_000001021360	ENOG4105DY2	Paraquat-inducible protein b
MADE_000001021365	ENOG4105F1S	paraquat-inducible protein a
MADE_000001021380	ENOG4105C5S	asparaginyl-tRNA synthetase
MADE_000001021450	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
MADE_000001021550	ENOG4108M8H	domain protein
MADE_000001021560	ENOG4105D60	lipoprotein releasing system transmembrane protein
MADE_000001021565	ENOG4105CK2	sodium dicarboxylate symporter
MADE_000001021575	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
MADE_000001021585	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
MADE_000001021605	ENOG4105DKT	Transcriptional regulator
MADE_000001021610	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
MADE_000001021680	ENOG4105EZE	Cupin 4 family protein
MADE_000001021690	ENOG4107QTF	adenylosuccinate lyase
MADE_000001021695	ENOG41075W9	High frequency lysogenization protein HflD homolog
MADE_000001021700	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
MADE_000001021705	ENOG4108R99	pseudouridine synthase
MADE_000001021715	ENOG4105E9K	Isocitrate dehydrogenase
MADE_000001021720	ENOG4105VEQ	Cold shock protein
MADE_000001021725	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
MADE_000001021735	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
MADE_000001021740	ENOG4105C3M	thioredoxin reductase
MADE_000001021745	ENOG4105PQ6	UPF0208 membrane protein
MADE_000001021750	ENOG4105GPY	SprT protein
MADE_000001021755	ENOG4105D07	Signal peptide peptidase, SppA
MADE_000001021770	ENOG41069NU	Nitroreductase
MADE_000001021780	ENOG4105HDK	L-asparaginase
MADE_000001021785	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
MADE_000001021790	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
MADE_000001021795	ENOG4108Z43	UPF0250 protein
MADE_000001021800	ENOG4105DZ1	carboxypeptidase
MADE_000001021805	ENOG4105K6T	rare lipoprotein A
MADE_000001021810	ENOG4105CNI	cell division protein FtsW
MADE_000001021815	ENOG4105CJN	penicillin-binding protein
MADE_000001021820	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
MADE_000001021825	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
MADE_000001021835	ENOG4105DJF	DNA polymerase III, delta' subunit
MADE_000001021840	ENOG4108U2H	Rare lipoprotein B
MADE_000001021845	ENOG4105C8T	Leucyl-tRNA synthetase
MADE_000001021855	ENOG4105DAN	ATP-dependent protease
MADE_000001021860	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
MADE_000001021865	ENOG4105BZU	Histidine kinase
MADE_000001021875	ENOG4105HBR	Rna-binding protein
MADE_000001021885	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
MADE_000001021895	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
MADE_000001021900	ENOG4105CP7	Triose-phosphate isomerase
MADE_000001021915	ENOG4105BZU	Histidine kinase
MADE_000001021945	ENOG4105CHR	reductase
MADE_000001021950	ENOG4108KP7	hydrolase
MADE_000001021965	ENOG4105CK7	Sodium proline symporter
MADE_000001022000	ENOG4105BZ1	(ABC) transporter
MADE_000001022010	ENOG4105D25	secreted protein
MADE_000001022025	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
MADE_000001022030	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
MADE_000001022045	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
MADE_000001022050	ENOG4108UQY	Iron-storage protein
MADE_000001022075	ENOG4105WH1	Two component transcriptional regulator luxr family
MADE_000001022080	ENOG4108MN8	Membrane
MADE_000001022110	ENOG4105CAT	Cytidine monophosphate kinase
MADE_000001022115	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
MADE_000001022120	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
MADE_000001022225	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
MADE_000001022230	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
MADE_000001022250	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
MADE_000001022270	ENOG4105CXG	d-lactate dehydrogenase
MADE_000001022275	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
MADE_000001022280	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
MADE_000001022295	ENOG4105EKQ	RNA-directed DNA polymerase
MADE_000001022305	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
MADE_000001022360	ENOG4105EKQ	RNA-directed DNA polymerase
MADE_000001022365	ENOG4107104	thymidine kinase
MADE_000001022380	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
MADE_000001022410	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
MADE_000001022415	ENOG4108RWN	rrna methyltransferase
MADE_000001022420	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
MADE_000001022435	ENOG4105C26	Dehydrogenase
MADE_000001022440	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
MADE_000001022455	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
MADE_000001022490	ENOG4105PWE	CRISPR-associated protein cas2
MADE_000001022605	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
MADE_000001022610	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
MADE_000001022640	ENOG4105CBC	glutamate synthase
MADE_000001022665	ENOG4105PE1	Receptor
MADE_000001022745	ENOG4109015	Biopolymer transport protein exbD tolR
MADE_000001022760	ENOG4105EJG	cellulose synthase
MADE_000001022765	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
MADE_000001022775	ENOG4107QZ7	Cellulose synthase catalytic subunit
MADE_000001022790	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
MADE_000001022795	ENOG4105K4T	epimerase
MADE_000001022805	ENOG4105KWG	Pfam:DUF1696
MADE_000001022810	ENOG4105BZU	Histidine kinase
MADE_000001022820	ENOG4105EFZ	amidohydrolase
MADE_000001022830	ENOG4105C5X	domain protein
MADE_000001022840	ENOG4108WAV	Transcriptional regulator
MADE_000001022845	ENOG4105E7A	Glutamine amidotransferase
MADE_000001022850	ENOG4108Z12	YiaAB two helix domain-containing protein
MADE_000001022870	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
MADE_000001022880	ENOG4105C26	Dehydrogenase
MADE_000001022885	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
MADE_000001022890	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
MADE_000001022895	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
MADE_000001022905	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
MADE_000001022910	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
MADE_000001022915	ENOG4108R86	Transcriptional regulator
MADE_000001022930	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
MADE_000001022935	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
MADE_000001022945	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
MADE_000001022955	ENOG4105CJ2	(LipO)protein
MADE_000001022960	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
MADE_000001022965	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
MADE_000001022970	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
MADE_000001022975	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
MADE_000001022980	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
MADE_000001022985	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
MADE_000001022990	ENOG4105RKW	reductase (By
MADE_000001022995	ENOG4108V1T	peptidylprolyl cis-trans isomerase
MADE_000001023000	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
MADE_000001023020	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
MADE_000001023025	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
MADE_000001023050	ENOG4105DBI	uridine monophosphokinase
MADE_000001023055	ENOG4105D9N	nucleoside
MADE_000001023075	ENOG4105BZU	Histidine kinase
MADE_000001023080	ENOG4107S1V	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
MADE_000001023090	ENOG4107QN1	sodium solute
MADE_000001023100	ENOG4105BZU	Histidine kinase
MADE_000001023110	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
MADE_000001023120	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
MADE_000001023135	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
MADE_000001023150	ENOG4105CPC	Aldo Keto reductase
MADE_000001023180	ENOG4105EKQ	RNA-directed DNA polymerase
MADE_000001023185	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
MADE_000001023210	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
MADE_000001023230	ENOG4108JJA	ABC, transporter
MADE_000001023235	ENOG41063Z6	transcriptional regulator, lysR family
MADE_000001023285	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
MADE_000001023290	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
MADE_000001023295	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
MADE_000001023300	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
MADE_000001023310	ENOG4108VZM	50s ribosomal protein L10
MADE_000001023315	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
MADE_000001023320	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
MADE_000001023340	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
MADE_000001023345	ENOG4105PM1	preprotein translocase subunit SecE
MADE_000001023355	ENOG4105BZ1	(ABC) transporter
MADE_000001023360	ENOG4105JSC	dimethylmenaquinone methyltransferase
MADE_000001023365	ENOG4105C9K	Endothelin-converting enzyme 1
MADE_000001023375	ENOG4105C1J	atp-dependent rna helicase
MADE_000001023380	ENOG4105EKE	dihydroorotase
MADE_000001023385	ENOG4105QNF	Outer membrane lipoprotein
MADE_000001023390	ENOG4107RGM	aldo keto reductase
MADE_000001023395	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
MADE_000001023405	ENOG4105DP8	Major facilitator superfamily MFS_1
MADE_000001023410	ENOG4107QW3	Sucrose phosphorylase
MADE_000001023420	ENOG4105EUJ	GTP cyclohydrolase i
MADE_000001023425	ENOG410642E	Short chain dehydrogenase
MADE_000001023430	ENOG4105DWY	Agmatine deiminase
MADE_000001023445	ENOG4107QRT	dEAD DEAH box helicase
MADE_000001023455	ENOG4107T0X	DNA ligase
MADE_000001023460	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
MADE_000001023465	ENOG4105D7K	pfkb domain protein
MADE_000001023475	ENOG4105C3R	Methionine synthase
MADE_000001023480	ENOG4105CYM	Glutathione S-transferase
MADE_000001023495	ENOG4107IFA	Lipase (EC 3.1.1.3)
MADE_000001023500	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
MADE_000001023525	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
MADE_000001023530	ENOG4105CFC	Transporter
MADE_000001023535	ENOG4105EPW	hflc protein
MADE_000001023540	ENOG4107QJR	hflk protein
MADE_000001023545	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
MADE_000001023550	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
MADE_000001023555	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
MADE_000001023560	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
MADE_000001023565	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
MADE_000001023570	ENOG4105K8N	protein family UPF0079, ATPase
MADE_000001023575	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
MADE_000001023580	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
MADE_000001023590	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
MADE_000001023600	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
MADE_000001023605	ENOG4105MYN	Zinc uptake regulation protein
MADE_000001023615	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
MADE_000001023620	ENOG4105CDV	Ompa motb domain protein
MADE_000001023625	ENOG4105CDU	Replicative dna helicase
MADE_000001023640	ENOG4105WD1	Membrane
MADE_000001023650	ENOG4107R3J	Transporter
MADE_000001023690	ENOG4105VEJ	Heat shock protein
MADE_000001023700	ENOG4105C0P	Mg chelatase subunit ChlI
MADE_000001023710	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
MADE_1000015	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
MADE_1000020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
MADE_1000025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
MADE_1000035	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
MADE_1000040	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
MADE_1000045	ENOG4108R3E	Dna-3-methyladenine glycosylase i
MADE_1000055	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
MADE_1000065	ENOG4106RE7	Cytochrome
MADE_1000070	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
MADE_1000075	ENOG4105C2M	dna polymerase I
MADE_1000080	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
MADE_1000085	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
MADE_1000090	ENOG4105C1A	potassium transporter peripheral membrane
MADE_1000095	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
MADE_1000100	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
MADE_1000105	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
MADE_1000115	ENOG4105C79	DNA protecting protein DprA
MADE_1000120	ENOG4108RPN	Protein smg homolog
MADE_1000130	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
MADE_1000135	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
MADE_1000140	ENOG4105EIF	outer membrane protein W
MADE_1000150	ENOG4105E2X	shikimate dehydrogenase
MADE_1000155	ENOG4108Z0R	Transferase
MADE_1000165	ENOG41061N2	exported protein
MADE_1000185	ENOG4105C0B	DNA polymerase III (alpha subunit)
MADE_1000215	ENOG4105IIU	Aminopeptidase
MADE_1000220	ENOG4106WTF	Glycosyl transferase, family 2
MADE_1000225	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
MADE_1000230	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
MADE_1000235	ENOG4105W5Q	DNA repair protein (RadC
MADE_1000260	ENOG4105E3R	(LipO)protein
MADE_1000265	ENOG4105KDC	50s ribosomal protein l28
MADE_1000270	ENOG4105W0E	50S ribosomal protein L33
MADE_1000280	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
MADE_1000285	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
MADE_1000290	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
MADE_1000295	ENOG4105DKP	glycosyl transferase, family 9
MADE_1000310	ENOG4105BZU	Histidine kinase
MADE_1000315	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
MADE_1000320	ENOG4105CPQ	Dehydrogenase
MADE_1000325	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
MADE_1000340	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
MADE_1000345	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
MADE_1000360	ENOG4105W0Z	cytoplasmic protein
MADE_1000365	ENOG4105C4R	Atp-dependent dna helicase
MADE_1000370	ENOG4105BZU	Histidine kinase
MADE_1000375	ENOG4105MPD	Cytochrome
MADE_1000395	ENOG4105DFD	Na H antiporter
MADE_1000415	ENOG4108VCT	Sulfite exporter TauE/SafE
MADE_1000430	ENOG4105D05	Receptor
MADE_1000445	ENOG4108JJ8	(ABC) transporter
MADE_1000450	ENOG4108JJ9	ABC, transporter
MADE_1000460	ENOG4105C4M	(Ubiquinol oxidase) subunit I
MADE_1000465	ENOG4105VFE	sira family
MADE_1000475	ENOG4105D3R	alkyl hydroperoxide reductase
MADE_1000485	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MADE_1000515	ENOG4105C94	Transporter
MADE_1000565	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
MADE_1000595	ENOG4105C3J	Cysteine desulfurase
MADE_1000630	ENOG4105D0S	secretion protein (HlyD
MADE_1000635	ENOG4105CJ1	ABC, transporter
MADE_1000640	ENOG4105CJ1	ABC, transporter
MADE_1000645	ENOG4105CMI	transporter
MADE_1000660	ENOG4105C1G	acyl-Coa dehydrogenase
MADE_1000665	ENOG4105DQS	Transcriptional regulator
MADE_1000675	ENOG4105CM6	amino acid regulated cytosolic protein
MADE_1000695	ENOG4105D41	biosynthesis protein thiH
MADE_1000700	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
MADE_1000710	ENOG4105D06	uba thif-type nad fad binding protein
MADE_1000715	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
MADE_1000720	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
MADE_1000725	ENOG410601J	HemY protein
MADE_1000730	ENOG4105ECF	c-methyltransferase
MADE_1000735	ENOG41076E6	Uroporphyrinogen-III Synthase
MADE_1000740	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
MADE_1000760	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
MADE_1000765	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
MADE_1000770	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
MADE_1000775	ENOG4105KME	endoribonuclease L-psp
MADE_1000780	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
MADE_1000785	ENOG4105CB5	ATP-dependent DNA helicase recG
MADE_1000790	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
MADE_1000810	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
MADE_1000815	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
MADE_1000825	ENOG4105CBX	hi0933 family
MADE_1000865	ENOG4105BZU	Histidine kinase
MADE_1000870	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
MADE_1000880	ENOG4105KPY	Small multidrug resistance protein
MADE_1000895	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
MADE_1000900	ENOG4105BZS	acriflavin resistance protein
MADE_1000910	ENOG4105CYC	Transferase
MADE_1000930	ENOG4108N3W	hemolysin secretion protein
MADE_1000940	ENOG4108NST	exported protein
MADE_1000945	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
MADE_1000950	ENOG4105BZU	Histidine kinase
MADE_1000965	ENOG4105C9U	ATP-dependent DNA helicase RecQ
MADE_1000970	ENOG4105CJW	magnesium transporter
MADE_1000975	ENOG4105FR1	rard protein
MADE_1000980	ENOG4105BZU	Histidine kinase
MADE_1000985	ENOG4105C4R	Atp-dependent dna helicase
MADE_1000990	ENOG4105D7W	serine acetyltransferase
MADE_1000995	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
MADE_1001000	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
MADE_1001010	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
MADE_1001015	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
MADE_1001035	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
MADE_1001045	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MADE_1001050	ENOG4105DFU	Cell wall formation (By similarity)
MADE_1001055	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MADE_1001065	ENOG4105F0N	pyrophosphate phospho-hydrolase
MADE_1001095	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
MADE_1001100	ENOG4107RDB	Major Facilitator
MADE_1001105	ENOG4107VXZ	Hydrolase
MADE_1001135	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
MADE_1001140	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
MADE_1001150	ENOG4107XMK	single-stranded DNA-binding protein
MADE_1001165	ENOG4105CMR	udp-glucose 4-epimerase
MADE_1001170	ENOG4105CNT	hydrolase family 2
MADE_1001185	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
MADE_1001190	ENOG4105E98	transcriptional regulator DeoR family
MADE_1001195	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
MADE_1001245	ENOG4107QHF	type ii secretion system protein e
MADE_1001250	ENOG4105D7Q	type ii secretion system
MADE_1001265	ENOG4108VAU	general secretion pathway protein G
MADE_1001295	ENOG4105DFF	Rod shape-determining protein mreb
MADE_1001300	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
MADE_1001305	ENOG4105VQ7	Rod shape-determining protein MreD
MADE_1001310	ENOG4108Z03	MAF-like protein
MADE_1001315	ENOG4105C03	ribonuclease
MADE_1001330	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
MADE_1001335	ENOG4105N42	UPF0307 protein
MADE_1001340	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
MADE_1001350	ENOG4105CNT	hydrolase family 2
MADE_1001355	ENOG41065U4	response regulator
MADE_1001360	ENOG4105BZU	Histidine kinase
MADE_1001365	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
MADE_1001370	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
MADE_1001375	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
MADE_1001380	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
MADE_1001385	ENOG4105CEN	a g-specific adenine glycosylase
MADE_1001390	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
MADE_1001445	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
MADE_1001465	ENOG4105C79	DNA protecting protein DprA
MADE_1001525	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
MADE_1001530	ENOG4105GR3	Histidine kinase
MADE_1001535	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
MADE_1001555	ENOG4108IJF	Heavy metal efflux pump, CzcA
MADE_1001640	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
MADE_1001655	ENOG4107JPU	
MADE_1001660	ENOG4108USZ	hydrogenase
MADE_1001670	ENOG4105E3S	small subunit
MADE_1001675	ENOG4105DPX	Hydrogenase, large subunit
MADE_1001690	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
MADE_1001695	ENOG4107RSS	Hydrogenase accessory protein HypB
MADE_1001700	ENOG4105CQS	hydrogenase expression formation protein HypD
MADE_1001710	ENOG4105C45	hydrogenase expression formation protein (HypE)
MADE_1001720	ENOG4105C59	p-type ATPase
MADE_1001820	ENOG4105PGM	cation diffusion facilitator family transporter
MADE_1001830	ENOG41080IJ	Diacylglycerol kinase
MADE_1001845	ENOG4105E5H	Transposase
MADE_1001850	ENOG4105DIJ	Phosphoethanolamine transferase
MADE_1001855	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
MADE_1001865	ENOG4105CKK	Glycosyl transferase, family 2
MADE_1001870	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
MADE_1001875	ENOG4105GR3	Histidine kinase
MADE_1001905	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
MADE_1001920	ENOG4105C59	p-type ATPase
MADE_1001960	ENOG4107R7I	amino acid
MADE_1001970	ENOG4105E3B	Multicopper oxidase
MADE_1001995	ENOG4105C8Q	Methyl-accepting chemotaxis
MADE_1002000	ENOG4108VYJ	response regulator receiver protein
MADE_1002005	ENOG4105CBS	Chea signal transduction histidine kinase
MADE_1002010	ENOG4108V3W	Chemotaxis protein, CheW
MADE_1002015	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
MADE_1002040	ENOG4105EKQ	RNA-directed DNA polymerase
MADE_1002060	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
MADE_1002085	ENOG4105ETE	Transcriptional regulator (LacI family
MADE_1002100	ENOG4105EAA	nucleoside
MADE_1002125	ENOG4105C0A	alcohol dehydrogenase
MADE_1002225	ENOG4105CM2	brancheD-chain amino acid aminotransferase
MADE_1002230	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
MADE_1002240	ENOG4107QM5	aconitate hydratase
MADE_1002250	ENOG4107QHF	type ii secretion system protein e
MADE_1002260	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
MADE_1002265	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
MADE_1002270	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
MADE_1002275	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MADE_1002280	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
MADE_1002285	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
MADE_1002290	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
MADE_1002295	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
MADE_1002300	ENOG41083MP	50s ribosomal protein l29
MADE_1002305	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
MADE_1002320	ENOG4105EKQ	RNA-directed DNA polymerase
MADE_1002325	ENOG4107RJ7	Glycosyl transferase (Group 1
MADE_1002335	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
MADE_1002355	ENOG41069D7	Methyl-accepting chemotaxis
MADE_1002360	ENOG4105DGW	oligopeptidase A
MADE_1002380	ENOG4105CQ7	ATP-dependent helicase
MADE_1002385	ENOG4105CVE	Lytic murein transglycosylase
MADE_1002390	ENOG4105BZ4	penicillin-binding protein
MADE_1002405	ENOG4105CKW	Inner membrane protein yedI
MADE_1002410	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
MADE_1002420	ENOG4108YZA	Nitrogen regulatory protein pii
MADE_1002430	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
MADE_1002435	ENOG4105EZR	dyp-type peroxidase family protein
MADE_1002445	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
MADE_1002450	ENOG4105CXT	aspartate transcarbamylase
MADE_1002475	ENOG4105BZU	Histidine kinase
MADE_1002480	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
MADE_1002490	ENOG4105BZU	Histidine kinase
MADE_1002500	ENOG4105C26	Dehydrogenase
MADE_1002510	ENOG4105C8Y	Acetylornithine aminotransferase
MADE_1002525	ENOG4105C31	Tryptophanyl-tRNA synthetase
MADE_1002530	ENOG4105DJV	ribulose-phosphate 3-epimerase
MADE_1002550	ENOG4105DFE	Dna adenine methylase
MADE_1002560	ENOG4105D49	3-dehydroquinate synthase
MADE_1002565	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
MADE_1002570	ENOG4105E4G	Type IV pilus
MADE_1002595	ENOG4108JQC	penicillin-binding protein 1A
MADE_1002600	ENOG4107R1I	NAD-dependent malic enzyme
MADE_1002610	ENOG4105CYM	Glutathione S-transferase
MADE_1002620	ENOG4105CH6	catalase
MADE_1002640	ENOG4107QZM	n-acetylglutamate synthase
MADE_1002645	ENOG4105CH7	arginosuccinase
MADE_1002650	ENOG4105CDH	Citrulline--aspartate ligase
MADE_1002660	ENOG4105CAS	nag kinase
MADE_1002665	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
MADE_1002670	ENOG4108Z5K	methylglyoxal synthase
MADE_1002680	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
MADE_1002685	ENOG4105E0F	Histidine kinase
MADE_1002690	ENOG4108EUD	Lysophospholipase
MADE_1002695	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
MADE_1002705	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
MADE_1002710	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
MADE_1002715	ENOG4105VW4	glutaredoxin 3
MADE_1002720	ENOG4107YZP	Rhodanese domain protein
MADE_1002725	ENOG41063SB	peptidase
MADE_1002730	ENOG4105PXI	polysaccharide deacetylase
MADE_1002750	ENOG4105DJ4	phosphatidylserine decarboxylase
MADE_1002755	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
MADE_1002760	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
MADE_1002790	ENOG4105C7K	acetolactate synthase
MADE_1002795	ENOG4108ZP8	Acetolactate synthase small subunit
MADE_1002810	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
MADE_1002815	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
MADE_1002820	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
MADE_1002830	ENOG4105F8V	Hydrolase, tatD family
MADE_1002840	ENOG4105D52	delta-aminolevulinic acid dehydratase
MADE_1002845	ENOG4105C9X	ppx gppa phosphatase
MADE_1002850	ENOG4105C1J	atp-dependent rna helicase
MADE_1002855	ENOG4105K63	Thioredoxin
MADE_1002865	ENOG4105CH2	amidohydrolase
MADE_1002870	ENOG4105BZU	Histidine kinase
MADE_1002875	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
MADE_1002880	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
MADE_1002885	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
MADE_1002905	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
MADE_1002915	ENOG4107QR8	Thioredoxin
MADE_1002935	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
MADE_1002940	ENOG4105C26	Dehydrogenase
MADE_1002955	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
MADE_1002960	ENOG4107S6Z	Na H antiporter
MADE_1002975	ENOG4105EHZ	conserved protein UCP016719
MADE_1002980	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MADE_1002985	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
MADE_1003015	ENOG4105K3M	)-transporter
MADE_1003025	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
MADE_1003030	ENOG4105I4A	GCN5-related N-acetyltransferase
MADE_1003060	ENOG41084S7	Plasmid maintenance system antidote protein
MADE_1003075	ENOG4105K4U	addiction module toxin, RelE StbE family
MADE_1003305	ENOG4105CHU	acetyl-coa acetyltransferase
MADE_1003310	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
MADE_1003315	ENOG4107SC1	transglycosylase
MADE_1003320	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
MADE_1003330	ENOG4105EAH	synthase
MADE_1003335	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
MADE_1003340	ENOG4105K46	50S ribosomal protein l27
MADE_1003345	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MADE_1003360	ENOG4108K5P	(LipO)protein
MADE_1003365	ENOG4108UM1	dedA family
MADE_1003370	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
MADE_1003375	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
MADE_1003380	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
MADE_1003385	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
MADE_1003390	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
MADE_1003400	ENOG4105C8Q	Methyl-accepting chemotaxis
MADE_1003440	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
MADE_1003445	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
MADE_1003450	ENOG4105HF0	Membrane
MADE_1003455	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
MADE_1003460	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
MADE_1003470	ENOG4105BZU	Histidine kinase
MADE_1003490	ENOG4105D3G	Pseudouridine synthase
MADE_1003495	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
MADE_1003510	ENOG4108IAB	Phoh family
MADE_1003520	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
MADE_1003525	ENOG4105C1J	atp-dependent rna helicase
MADE_1003545	ENOG4105DFG	type I secretion outer membrane protein
MADE_1003550	ENOG41087AY	ADP-Ribose pyrophosphatase
MADE_1003560	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
MADE_1003565	ENOG4105IPS	esterase
MADE_1003570	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
MADE_1003580	ENOG4107VXZ	Hydrolase
MADE_1003605	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
MADE_1003610	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
MADE_1003615	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
MADE_1003620	ENOG4105UGU	tonB-dependent Receptor
MADE_1003630	ENOG41068WN	
MADE_1003635	ENOG4105CNM	Receptor
MADE_1003645	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
MADE_1003650	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
MADE_1003660	ENOG4105M85	Bola protein
MADE_1003690	ENOG4105CHH	sulfate transporter
MADE_1003695	ENOG4107QZF	nitrite reductase NADPH large subunit
MADE_1003710	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
MADE_1003715	ENOG4108I0Q	anthranilate phosphoribosyltransferase
MADE_1003720	ENOG4107SDU	Methyl-accepting chemotaxis
MADE_1003735	ENOG4105D7T	ABC transporter
MADE_1003750	ENOG4108Z33	Thiol disulfide Interchange Protein
MADE_1003755	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
MADE_1003780	ENOG4105VCC	30S ribosomal protein S21
MADE_1003785	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
MADE_1003795	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
MADE_1003800	ENOG4107ZVW	dihydroneopterin aldolase
MADE_1003810	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
MADE_1003815	ENOG4105K59	histidine triad (HIT) protein
MADE_1003830	ENOG4105DKK	Benzoate
MADE_1003835	ENOG4108JCI	Transcriptional regulator
MADE_1003840	ENOG4105DH7	May be involved in recombination (By similarity)
MADE_1003845	ENOG4105BZU	Histidine kinase
MADE_1003850	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
MADE_1003855	ENOG4105BZU	Histidine kinase
MADE_1003890	ENOG4109015	Biopolymer transport protein exbD tolR
MADE_1003895	ENOG41067XB	TonB family
MADE_1003905	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
MADE_1003910	ENOG4105BZU	Histidine kinase
MADE_1003915	ENOG4105CEY	Amp-dependent synthetase and ligase
MADE_1003930	ENOG4107QIJ	Aconitate hydratase 2
MADE_1003935	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
MADE_1003950	ENOG4107QIJ	Aconitate hydratase 2
MADE_1003960	ENOG4105CFH	Aspartokinase
MADE_1003965	ENOG4105C8Q	Methyl-accepting chemotaxis
MADE_1003970	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
MADE_1003975	ENOG4105NWN	ApaG protein
MADE_1003980	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
MADE_1003985	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
MADE_1003990	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
MADE_1003995	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
MADE_1004000	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
MADE_1004005	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
MADE_1004010	ENOG4105T95	Thiol disulfide interChange protein
MADE_1004015	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
MADE_1004025	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
MADE_1004030	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
MADE_1004035	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
MADE_1004040	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
MADE_1004045	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
MADE_1004050	ENOG4105DXN	mazG family
MADE_1004085	ENOG4105CEY	Amp-dependent synthetase and ligase
MADE_1004095	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
MADE_1004105	ENOG4105CKK	Glycosyl transferase, family 2
MADE_1004125	ENOG4105DHQ	Histidine kinase
MADE_1004135	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
MADE_1004140	ENOG4108UJD	30S ribosomal protein S9
MADE_1004145	ENOG4105EIX	cytochrome c1
MADE_1004150	ENOG4107MKT	Stringent starvation protein a
MADE_1004155	ENOG4105KB2	stringent starvation protein b
MADE_1004160	ENOG4105CJW	magnesium transporter
MADE_1004165	ENOG41080Z8	PHOSPHOCARRIER protein
MADE_1004170	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
MADE_1004175	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
MADE_1004180	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
MADE_1004185	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
MADE_1004190	ENOG4108IUZ	ABC transporter
MADE_1004195	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
MADE_1004205	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
MADE_1004210	ENOG4105C2X	Arabinose 5-phosphate isomerase
MADE_1004220	ENOG4105DHJ	ABC, transporter
MADE_1004225	ENOG4105CY3	ABC transporter, permease
MADE_1004230	ENOG4107PE3	Mammalian cell entry related domain protein
MADE_1004235	ENOG4105E3I	toluene tolerance
MADE_1004245	ENOG4105VFK	BolA family
MADE_1004250	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
MADE_1004255	ENOG4105C0H	protease
MADE_1004260	ENOG4105C0H	protease
MADE_1004270	ENOG4105D6Z	AFG1 family ATPase
MADE_1004275	ENOG4105CDY	transcriptional regulatory protein
MADE_1004295	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
MADE_1004305	ENOG4105D05	Receptor
MADE_1004310	ENOG4108RNG	Permease of the drug metabolite transporter
MADE_1004320	ENOG4105BZU	Histidine kinase
MADE_1004340	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
MADE_1004345	ENOG4105CV1	Transketolase (EC 2.2.1.1)
MADE_1004350	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
MADE_1004355	ENOG4105BZA	Phosphoglycerate kinase
MADE_1004360	ENOG4105WYW	fructose-bisphosphate aldolase
MADE_1004370	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
MADE_1004375	ENOG4105C9X	ppx gppa phosphatase
MADE_1004390	ENOG4105C8U	phosphate abc transporter
MADE_1004400	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
MADE_1004410	ENOG4105CJ3	phosphate transporter
MADE_1004420	ENOG4105C5Q	Transcriptional regulator
MADE_1004430	ENOG4108UT2	hemolysin iii
MADE_1004435	ENOG4105K56	Transcriptional regulator
MADE_1004440	ENOG4108ZHJ	Organic hydroperoxide resistance protein
MADE_1004455	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
MADE_1004465	ENOG4107RH8	nuclease SbcCD subunit D
MADE_1004470	ENOG4105EYH	Exonuclease
MADE_1004485	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
MADE_1004495	ENOG4105CI2	imidazolone-5-propionate hydrolase
MADE_1004500	ENOG4105CZE	histidine utilization repressor
MADE_1004505	ENOG4105CGP	Urocanate hydratase
MADE_1004510	ENOG4105C84	Histidine ammonia-lyase
MADE_1004540	ENOG4105C5H	ABC transporter
MADE_1004565	ENOG4105D64	Mechanosensitive ion channel
MADE_1004625	ENOG41067MG	lrgb family
MADE_1004655	ENOG4105CSA	Coproporphyrinogen iii oxidase
MADE_1004665	ENOG4105C1J	atp-dependent rna helicase
MADE_1004670	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MADE_1004685	ENOG4105CPI	Metal Dependent Phosphohydrolase
MADE_1004690	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
MADE_1004695	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
MADE_1004700	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
MADE_1004705	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
MADE_1004715	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
MADE_1004720	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
MADE_1004725	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
MADE_1004735	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
MADE_1004740	ENOG4108IUW	ABC transporter
MADE_1004745	ENOG4108SDH	ABC, transporter
MADE_1004760	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
MADE_1004765	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
MADE_1004770	ENOG41060IM	Heme exporter protein
MADE_1004775	ENOG4105X3C	heme exporter protein
MADE_1004780	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
MADE_1004785	ENOG4105DA4	cytochrome c-type biogenesis protein
MADE_1004790	ENOG4107QX9	Thiol disulfide interChange protein
MADE_1004795	ENOG4108M1T	Cytochrome c-type biogenesis protein
MADE_1004805	ENOG410903C	(LipO)protein
MADE_1004810	ENOG4105CMR	udp-glucose 4-epimerase
MADE_1004820	ENOG4105DUX	Transporter
MADE_1004840	ENOG4107V1M	polysaccharide export protein
MADE_1004850	ENOG4105ESV	Glycosyl transferase, family 4
MADE_1004865	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
MADE_1004870	ENOG4105KQC	Competence protein
MADE_1004875	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
MADE_1004890	ENOG4105EWT	decarboxylase family
MADE_1004895	ENOG4105BZU	Histidine kinase
MADE_1004900	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
MADE_1004905	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
MADE_1004940	ENOG4105DR9	pseudouridine synthase
MADE_1004945	ENOG4105QDK	Flavodoxin
MADE_1004950	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
MADE_1005215	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
MADE_1005220	ENOG4105CUT	histidyl-tRNA synthetase
MADE_1005225	ENOG4105N21	Membrane
MADE_1005230	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
MADE_1005235	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
MADE_1005250	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
MADE_1005255	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
MADE_1005260	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
MADE_1005275	ENOG4108NVR	Methyl-accepting chemotaxis
MADE_1005285	ENOG4105HDD	phospholipase
MADE_1005290	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
MADE_1005295	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
MADE_1005300	ENOG4108R96	Methyltransferase, YaeB family
MADE_1005310	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
MADE_1005320	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
MADE_1005335	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
MADE_1005340	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
MADE_1005345	ENOG4105KNE	Phosphatidate cytidylyltransferase
MADE_1005350	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
MADE_1005360	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MADE_1005365	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
MADE_1005370	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
MADE_1005375	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
MADE_1005380	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
MADE_1005385	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
MADE_1005390	ENOG4105C0B	DNA polymerase III (alpha subunit)
MADE_1005395	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
MADE_1005400	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
MADE_1005405	ENOG4105BZU	Histidine kinase
MADE_1005420	ENOG4108Z6B	deaminase
MADE_1005430	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
MADE_1005435	ENOG4108ETH	Formylglycinamide ribotide synthetase
MADE_1005445	ENOG4108DG9	Smr protein MutS2
MADE_1005485	ENOG4105CDV	Ompa motb domain protein
MADE_1005490	ENOG4105BZ1	(ABC) transporter
MADE_1005540	ENOG4108VSE	mercuric transport protein
MADE_1005555	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
MADE_1005640	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
MADE_1005655	ENOG4105WH1	Two component transcriptional regulator luxr family
MADE_1005695	ENOG4107R88	Chemotaxis protein (CheV)
MADE_1005700	ENOG4105BZU	Histidine kinase
MADE_1005705	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
MADE_1005710	ENOG4108ZC9	flagellar basal-body rod protein flgc
MADE_1005715	ENOG4105W00	Flagellar hook capping protein
MADE_1005720	ENOG4105BZE	flagellar hook protein, FlgE
MADE_1005725	ENOG4108KPB	Flagellar basal-body rod protein FlgF
MADE_1005730	ENOG4105CGA	flagellar basal-body rod protein FlgG
MADE_1005735	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
MADE_1005740	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
MADE_1005745	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
MADE_1005755	ENOG4105DTJ	flagellar hook-associated protein
MADE_1005760	ENOG4105I03	Flagellin
MADE_1005770	ENOG4105I03	Flagellin
MADE_1005780	ENOG4105DTS	flagellar hook-associated
MADE_1005785	ENOG4105MQ3	flagellar protein FliS
MADE_1005825	ENOG4105EQR	Transposase IS116 IS110 IS902
MADE_1005845	ENOG4105CMM	transposase
MADE_1005860	ENOG4105F0R	Cytidylyltransferase
MADE_1005865	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
MADE_1005870	ENOG4105C5E	polysaccharide biosynthesis protein
MADE_1005875	ENOG4105I03	Flagellin
MADE_1005880	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
MADE_1005885	ENOG4105BZU	Histidine kinase
MADE_1005890	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
MADE_1005895	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
MADE_1005900	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
MADE_1005905	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
MADE_1005915	ENOG4108JIR	Flagellum-specific ATP synthase
MADE_1005935	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
MADE_1005940	ENOG4105DD5	Flagellar motor switch protein
MADE_1005945	ENOG4105VTB	flagellar biosynthesis protein fliO
MADE_1005950	ENOG4105CN7	Flagellar biosynthetic protein FliP
MADE_1005955	ENOG4105VS8	Flagellar biosynthetic protein fliq
MADE_1005960	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
MADE_1005965	ENOG4105D00	flagellar biosynthetic protein flhB
MADE_1005970	ENOG4105D7B	Flagellar biosynthesis protein flha
MADE_1005975	ENOG4105FZW	flagellar biosynthesis regulator FlhF
MADE_1005985	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
MADE_1005990	ENOG4108VYJ	response regulator receiver protein
MADE_1005995	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
MADE_1006000	ENOG4105CBS	Chea signal transduction histidine kinase
MADE_1006010	ENOG4107QJE	Chromosome Partitioning Protein
MADE_1006020	ENOG4105YFD	chemotaxis, protein
MADE_1006030	ENOG4105CVG	Homoserine O-transsuccinylase
MADE_1006035	ENOG4105C3R	Methionine synthase
MADE_1006040	ENOG4105C3R	Methionine synthase
MADE_1006050	ENOG4105NBK	UPF0345 protein
MADE_1006055	ENOG4105DZ2	Transcriptional regulator
MADE_1006060	ENOG4105C5Q	Transcriptional regulator
MADE_1006065	ENOG4107B2H	carbonic anhydrase
MADE_1006070	ENOG4105CHH	sulfate transporter
MADE_1006085	ENOG4105C9K	Endothelin-converting enzyme 1
MADE_1006095	ENOG4108004	Modulates RecA activity (By similarity)
MADE_1006100	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
MADE_1006105	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
MADE_1006120	ENOG4107QSA	Oxaloacetate decarboxylase
MADE_1006125	ENOG4105D9Q	decarboxylase (Beta subunit)
MADE_1006130	ENOG4108JQ2	peptide transport system atp-binding protein
MADE_1006135	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
MADE_1006140	ENOG4108EU3	peptide transport system, permease
MADE_1006145	ENOG4108I5W	peptide transport system, permease protein
MADE_1006150	ENOG4105DEF	Extracellular solute-binding protein, family 5
MADE_1006155	ENOG4105E51	psp operon transcriptional activator
MADE_1006160	ENOG41087YS	Phage shock protein A
MADE_1006175	ENOG4105MIR	Phenylalanine 4-monooxygenase
MADE_1006190	ENOG4108RXX	maleylacetoacetate isomerase
MADE_1006195	ENOG4108XM1	transcriptional regulator AsnC family
MADE_1006210	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
MADE_1006265	ENOG4109015	Biopolymer transport protein exbD tolR
MADE_1006270	ENOG410822N	TonB family
MADE_1006285	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
MADE_1006320	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
MADE_1006335	ENOG4105HEI	LysR family (Transcriptional regulator
MADE_1006350	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
MADE_1006355	ENOG4105CV8	reductase
MADE_1006380	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
MADE_1006385	ENOG4105C75	arginyL-tRNA synthetase
MADE_1006395	ENOG4105EKQ	RNA-directed DNA polymerase
MADE_1006425	ENOG4105BZU	Histidine kinase
MADE_1006430	ENOG4108KBJ	Inner membrane protein YkgB
MADE_1006455	ENOG4105F57	Anthranilate dioxygenase reductase
MADE_1006470	ENOG4105CRK	lysyL-tRNA synthetase
MADE_1006475	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
MADE_1006480	ENOG4108W1A	pseudouridine synthase
MADE_1006495	ENOG4105D9M	gamma-glutamylcysteine synthetase
MADE_1006520	ENOG4108DG9	Smr protein MutS2
MADE_1006525	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
MADE_1006530	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
MADE_1006540	ENOG4105ED1	spovr family
MADE_1006545	ENOG4106AKX	UPF0229 protein
MADE_1006550	ENOG4105CYN	Serine protein kinase
MADE_1006555	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
MADE_1006560	ENOG4105M2J	Glutaredoxin
MADE_1006565	ENOG4105D05	Receptor
MADE_1006580	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
MADE_1006590	ENOG4105D3R	alkyl hydroperoxide reductase
MADE_1006595	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
MADE_1006600	ENOG4105EIY	sodium-type flagellar protein motY
MADE_1006605	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
MADE_1006610	ENOG4108UYE	Lactoylglutathione lyase
MADE_1006615	ENOG4105VEQ	Cold shock protein
MADE_1006635	ENOG4105DZB	Electron transport complex
MADE_1006640	ENOG4108UQQ	Electron transport complex
MADE_1006645	ENOG4105D6A	Electron transport complex
MADE_1006655	ENOG4108R3D	Electron transport complex
MADE_1006660	ENOG4105DGN	Electron transport complex
MADE_1006665	ENOG4107QJQ	Mate efflux family protein
MADE_1006670	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
MADE_1006680	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
MADE_1006685	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
MADE_1006695	ENOG4105CAQ	asparagine synthetase
MADE_1006725	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
MADE_1006730	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
MADE_1006735	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
MADE_1006740	ENOG4105C11	sulfate adenylyltransferase), subunit 2
MADE_1006745	ENOG4105CK7	Sodium proline symporter
MADE_1006750	ENOG4105BZU	Histidine kinase
MADE_1006795	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
MADE_1006800	ENOG4105CHU	acetyl-coa acetyltransferase
MADE_1006820	ENOG4108UJV	acyl-CoA thioesterase i
MADE_1006825	ENOG4108I0Y	(ABC) transporter
MADE_1006830	ENOG4105CV6	ABC transporter, permease
MADE_1006835	ENOG4105ECP	epimerase
MADE_1006840	ENOG4105KKP	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
MADE_1006845	ENOG4105DSF	transport protein
MADE_1006855	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
MADE_1006870	ENOG4105K9H	YciI-like protein
MADE_1006875	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
MADE_1006880	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
MADE_1006885	ENOG4105DK0	Indole-3-glycerol phosphate synthase
MADE_1006890	ENOG4108I0Q	anthranilate phosphoribosyltransferase
MADE_1006900	ENOG4105CRQ	synthase (Component I)
MADE_1006905	ENOG4105DB7	PHP domain protein
MADE_1006910	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
MADE_1006915	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
MADE_1006920	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
MADE_1006925	ENOG4105FE9	pseudouridine synthase
MADE_1006930	ENOG4105CV8	reductase
MADE_1006935	ENOG4108UW5	maltose o-acetyltransferase
MADE_1006945	ENOG4106BRA	Membrane
MADE_1006960	ENOG4108JJ6	Type I secretion system ATPase
MADE_1006970	ENOG4105FQ6	thiopurine methyltransferase
MADE_1006975	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
MADE_1006980	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
MADE_1006985	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
MADE_1006990	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
MADE_1006995	ENOG4105C0A	alcohol dehydrogenase
MADE_1007000	ENOG4105DTD	Dehydrogenase
MADE_1007010	ENOG4105DWV	Homoserine O-trans-acetylase
MADE_1007015	ENOG4105CY2	Citrate transporter
MADE_1007045	ENOG4105BZU	Histidine kinase
MADE_1007050	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MADE_1007055	ENOG4105CFG	Acts as a chaperone (By similarity)
MADE_1007060	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
MADE_1007065	ENOG41085AF	Cytochrome
MADE_1007070	ENOG4108M8H	domain protein
MADE_1007075	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
MADE_1007085	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
MADE_1007090	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
MADE_1007095	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
MADE_1007100	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
MADE_1007120	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
MADE_1007125	ENOG4105C6K	Malic enzyme
MADE_1007135	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
MADE_1007140	ENOG4108JU5	Magnesium and cobalt efflux protein
MADE_1007145	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
MADE_1007150	ENOG4105C9A	Phoh family
MADE_1007155	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
MADE_1007160	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
MADE_1007200	ENOG4107RNH	Outer membrane receptor FepA
MADE_1007205	ENOG4108S4H	thioesterase Superfamily protein
MADE_1007210	ENOG4107XWI	flavin reductase domain protein, FMN-binding
MADE_1007220	ENOG4105BZG	amino acid carrier protein
MADE_1007230	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
MADE_1007250	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
MADE_1007255	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
MADE_1007260	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
MADE_1007265	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
MADE_1007270	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
MADE_1007275	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
MADE_1007280	ENOG4105KJF	protein tyrosine phosphatase
MADE_1007285	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
MADE_1007290	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
MADE_1007295	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
MADE_1007310	ENOG4108JJ7	ABC transporter
MADE_1007315	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
MADE_1007325	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
MADE_1007350	ENOG4105BZU	Histidine kinase
MADE_1007395	ENOG4107QPN	acyl-Coa dehydrogenase
MADE_1007410	ENOG4105D1S	lipid A biosynthesis
MADE_1007420	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
MADE_1007440	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
MADE_1007445	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
MADE_1007450	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
MADE_1007465	ENOG4108QV3	biosynthesis protein
MADE_1007520	ENOG4105CKK	Glycosyl transferase, family 2
MADE_1007540	ENOG41090RK	glycosyl transferase
MADE_1007550	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
MADE_1007555	ENOG4105C3G	gtp-binding protein
MADE_1007560	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
MADE_1007570	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
MADE_1007575	ENOG4105DQ4	alcohol dehydrogenase
MADE_1007595	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
MADE_1007600	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
MADE_1007640	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
MADE_1007645	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
MADE_1007650	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
MADE_1007655	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
MADE_1007665	ENOG4108YY7	Invasion gene expression up-regulator SirB
MADE_1007670	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
MADE_1007680	ENOG4105ETT	transcriptional Regulator, LysR family
MADE_1007690	ENOG4105M08	Membrane
MADE_1007695	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
MADE_1007700	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
MADE_1007715	ENOG4107TPY	serine threonine protein kinase
MADE_1007720	ENOG4105TMB	Formate nitrite transporter
MADE_1007725	ENOG4105F8C	transglutaminase domain-containing protein
MADE_1007735	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
MADE_1007740	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
MADE_1007745	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
MADE_1007750	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
MADE_1007755	ENOG4105BZU	Histidine kinase
MADE_1007760	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
MADE_1007770	ENOG4105K8R	UPF0145 protein
MADE_1007790	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
MADE_1007795	ENOG4105KUZ	arsenate reductase
MADE_1007805	ENOG4107RBJ	symporter
MADE_1007840	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
MADE_1007850	ENOG4105BZU	Histidine kinase
MADE_1007860	ENOG4105BZU	Histidine kinase
MADE_1007880	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
MADE_1007905	ENOG4105BZU	Histidine kinase
MADE_1007915	ENOG4107QUY	Guanine deaminase
MADE_1007935	ENOG4105C7W	Xanthine dehydrogenase
MADE_1007945	ENOG4108R86	Transcriptional regulator
MADE_1007960	ENOG4105C7N	Xanthine uracil vitamin C permease
MADE_1007965	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
MADE_1007975	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
MADE_1007985	ENOG4105BZU	Histidine kinase
MADE_1007990	ENOG4105BZU	Histidine kinase
MADE_1008005	ENOG4105C2W	permease
MADE_1008020	ENOG4105C5R	Aminotransferase
MADE_1008025	ENOG4105HF0	Membrane
MADE_1008030	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
MADE_1008070	ENOG4105CHR	reductase
MADE_1008080	ENOG4105C22	threonyL-tRNA synthetase
MADE_1008085	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
MADE_1008090	ENOG41082NX	50s ribosomal protein l35
MADE_1008095	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
MADE_1008100	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
MADE_1008105	ENOG4105D3Q	Sugar transferase
MADE_1008115	ENOG4105DAY	polysaccharide export protein
MADE_1008120	ENOG4108QV3	biosynthesis protein
MADE_1008125	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
MADE_1008150	ENOG4105BZU	Histidine kinase
MADE_1008180	ENOG4108SHN	Glycosyl transferase, family 2
MADE_1008195	ENOG4107T8Q	Glycosyl transferase (Group 1
MADE_1008215	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
MADE_1008230	ENOG4105JEU	Glycosyl transferase, family 2
MADE_1008240	ENOG4105F2I	Transposase
MADE_1008245	ENOG4105EXC	Acyl-transferase
MADE_1008250	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
MADE_1008265	ENOG4107QPH	glycogen) synthase
MADE_1008275	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
MADE_1008280	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
MADE_1008285	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
MADE_1008295	ENOG4108Z66	YbaK ebsC protein
MADE_1008300	ENOG4105CUJ	penicillin amidase
MADE_1008305	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
MADE_1008310	ENOG4108WBT	adenosyltransferase
MADE_1008320	ENOG4108JA2	transcriptioN-repair coupling factor
MADE_1008330	ENOG4105D60	lipoprotein releasing system transmembrane protein
MADE_1008355	ENOG4105CGK	Exodeoxyribonuclease III
MADE_1008390	ENOG4105DNH	Major Facilitator
MADE_1008400	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
MADE_1008425	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
MADE_1008435	ENOG4108UKI	Enoyl-CoA hydratase
MADE_1008440	ENOG4107QX3	carboxylase
MADE_1008445	ENOG4105C1G	acyl-Coa dehydrogenase
MADE_1008450	ENOG4108Z6Z	Transcriptional regulator
MADE_1008455	ENOG4105CHU	acetyl-coa acetyltransferase
MADE_1008470	ENOG4105BZU	Histidine kinase
MADE_1008480	ENOG4105CJB	Exodeoxyribonuclease I
MADE_1008485	ENOG4105BZU	Histidine kinase
MADE_1008490	ENOG4105D44	asparaginase
MADE_1008535	ENOG4105CQ7	ATP-dependent helicase
MADE_1008550	ENOG4105DR4	Methyltransferase
MADE_1008555	ENOG4108JA1	polyketide synthase
MADE_1008560	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
MADE_1008565	ENOG4107RZZ	dna polymerase iii epsilon subunit
MADE_1008585	ENOG4107RDJ	Sulfotransferase
MADE_1008595	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
MADE_1008600	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
MADE_1008625	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
MADE_1008630	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
MADE_1008635	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
MADE_1008640	ENOG4107YB6	acetyltransferase, (GNAT) family
MADE_1008655	ENOG4105C03	ribonuclease
MADE_1008660	ENOG4105EI2	Pseudouridine synthase
MADE_1008670	ENOG4108UHJ	MAF-like protein
MADE_1008675	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
MADE_1008680	ENOG4105VGS	50s ribosomal protein l32
MADE_1008695	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
MADE_1008705	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
MADE_1008710	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
MADE_1008720	ENOG4105HHA	aminodeoxychorismate lyase
MADE_1008725	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
MADE_1008730	ENOG4107QRG	dna polymerase iii
MADE_1008735	ENOG4105F8V	Hydrolase, tatD family
MADE_1008750	ENOG4105BZU	Histidine kinase
MADE_1008770	ENOG4105CHR	reductase
MADE_1008775	ENOG4108J2P	Alpha beta hydrolase fold
MADE_1008785	ENOG4105CHU	acetyl-coa acetyltransferase
MADE_1008790	ENOG4105CSU	acyl-Coa dehydrogenase
MADE_1008795	ENOG4105BZS	acriflavin resistance protein
MADE_1008800	ENOG410624X	efflux transporter, rnd family, mfp subunit
MADE_1008810	ENOG4105MP9	class II Aldolase
MADE_1008815	ENOG4105CXK	mandelate racemase muconate lactonizing
MADE_1008825	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
MADE_1008830	ENOG4105CSU	acyl-Coa dehydrogenase
MADE_1008845	ENOG4105C58	cytochrome c oxidase accessory protein ccog
MADE_1008855	ENOG4105DEI	Mannitol dehydrogenase
MADE_1008860	ENOG4105F2I	Transposase
MADE_1008885	ENOG4105D8X	mechanosensitive ion channel
MADE_1008890	ENOG4105D05	Receptor
MADE_1008895	ENOG4105KZX	Pterin carbinolamine dehydratase
MADE_1008900	ENOG4105BZU	Histidine kinase
MADE_1008905	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
MADE_1008910	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
MADE_1008915	ENOG4105CHV	Transcription elongation factor NusA
MADE_1008920	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
MADE_1008925	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
MADE_1008930	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
MADE_1008940	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
MADE_1008945	ENOG4105FE9	pseudouridine synthase
MADE_1008955	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
MADE_1008995	ENOG4105D3R	alkyl hydroperoxide reductase
MADE_1009040	ENOG4105CCT	upf0313 protein
MADE_1009055	ENOG4105D05	Receptor
MADE_1009060	ENOG4107QN2	dihydrolipoyl dehydrogenase
MADE_1009070	ENOG4105VNH	ABC transporter solute-binding protein
MADE_1009080	ENOG4108VGW	abc transporter atp-binding protein
MADE_1009085	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
MADE_1009155	ENOG4105CJ1	ABC, transporter
MADE_1009160	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
MADE_1009165	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
MADE_1009170	ENOG4108Z1B	Cyclase dehydrase
MADE_1009175	ENOG4105VDB	UPF0125 protein
MADE_1009185	ENOG4105C94	Transporter
MADE_1009190	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
MADE_1009360	ENOG4105EXN	Sulfate transport protein CysZ
MADE_1009365	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
MADE_1009370	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
MADE_1009410	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
MADE_1009415	ENOG4105W49	UPF0434 protein
MADE_1009420	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
MADE_1009430	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
MADE_1009445	ENOG4105CUZ	uba thif-type nad fad binding protein
MADE_1009450	ENOG4105CHF	Glutathione S-transferase
MADE_1009455	ENOG4105EUB	pirin domain protein
MADE_1009460	ENOG4107QKV	phosphomannomutase
MADE_1009470	ENOG4105BZN	citrate synthase
MADE_1009475	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
MADE_1009480	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
MADE_1009485	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
MADE_1009490	ENOG4105E33	succinate dehydrogenase
MADE_1009495	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
MADE_1009500	ENOG4105C7S	Dehydrogenase
MADE_1009505	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
MADE_1009510	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
MADE_1009520	ENOG4105QV4	Tryptophan halogenase
MADE_1009535	ENOG4108NRW	Phospholipase, patatin family
MADE_1009560	ENOG4108IUK	alpha amylase, catalytic
MADE_1009575	ENOG4105ETE	Transcriptional regulator (LacI family
MADE_1009580	ENOG4105CX6	glutaminyL-tRNA synthetase
MADE_1009585	ENOG4105UBK	short-chain dehydrogenase reductase
MADE_1009590	ENOG4108M0H	Extracellular lipase
MADE_1009595	ENOG4107SQI	penicillin amidase
MADE_1009600	ENOG4105ERU	peptidase
MADE_1009615	ENOG4107QNR	UPF0135 protein
MADE_1009620	ENOG4106371	Methyltransferase
MADE_1009625	ENOG4105C5I	Dehydrogenase
MADE_1009630	ENOG4108V06	Glutathione peroxidase
MADE_1009635	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
MADE_1009645	ENOG4105C1G	acyl-Coa dehydrogenase
MADE_1009650	ENOG4105E39	Enoyl-CoA hydratase
MADE_1009660	ENOG4105DHI	Methyltransferase
MADE_1009665	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
MADE_1009670	ENOG4105E68	Sulfatase
MADE_1009675	ENOG4105YDX	UPF0352 protein
MADE_1009680	ENOG4106V8H	Nucleoid-associated protein
MADE_1009710	ENOG4108HRK	Histidine kinase
MADE_1009715	ENOG4108VAC	response regulator
MADE_1009720	ENOG4105CTQ	phosphohexokinase
MADE_1009740	ENOG410600T	transposase
MADE_1009750	ENOG4105CPQ	Dehydrogenase
MADE_1009760	ENOG4105EMU	Dehydrogenase
MADE_1009765	ENOG4105EJC	lysr family transcriptional regulator
MADE_1009805	ENOG4105BZU	Histidine kinase
MADE_1009815	ENOG4105C72	UPF0176 protein
MADE_1009825	ENOG4105C1J	atp-dependent rna helicase
MADE_1009835	ENOG4105D6N	CoA-transferase, subunit a
MADE_1009840	ENOG4105F04	LysR family Transcriptional regulator
MADE_1009855	ENOG4107R11	Transcriptional regulator
MADE_1009870	ENOG4105CRQ	synthase (Component I)
MADE_1009885	ENOG4105CGY	Dna recombination protein
MADE_1009890	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
MADE_1009905	ENOG4105CPP	Dehydrogenase, E1 component
MADE_1009915	ENOG4105D6S	protein involved in catabolism of external DNA
MADE_1009930	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
MADE_1009940	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
MADE_1009960	ENOG4105CIS	alcohol dehydrogenase
MADE_1009980	ENOG4105KVH	Transcriptional regulator
MADE_1009995	ENOG4107S78	Band 7 protein
MADE_1010005	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
MADE_1010010	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
MADE_1010015	ENOG4105C8N	cysteinyl-tRNA synthetase
MADE_1010040	ENOG4105E9H	Lytic Murein transglycosylase
MADE_1010045	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
MADE_1010050	ENOG4105D1A	Methyltransferase
MADE_1010060	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
MADE_1010065	ENOG4105D1F	ATP-binding protein
MADE_1010070	ENOG4105DHP	deoxycytidine triphosphate deaminase
MADE_1010075	ENOG4105C8P	)-transporter
MADE_1010105	ENOG4108Z0R	Transferase
MADE_1010110	ENOG4105C5R	Aminotransferase
MADE_1010120	ENOG4108ZGC	gaf domain protein
MADE_1010130	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
MADE_1010135	ENOG4105CN1	protease
MADE_1010140	ENOG4105C8J	)-transporter
MADE_1010145	ENOG4105DFD	Na H antiporter
MADE_1010150	ENOG4105CD8	aminopeptidase N
MADE_1010165	ENOG4105C7I	Dehydrogenase
MADE_1010170	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
MADE_1010175	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
MADE_1010185	ENOG4105C5H	ABC transporter
MADE_1010195	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
MADE_1010200	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
MADE_1010205	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
MADE_1010210	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
MADE_1010215	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
MADE_1010280	ENOG4105PGM	cation diffusion facilitator family transporter
MADE_1010305	ENOG4105GAV	receptor
MADE_1010360	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
MADE_1010370	ENOG41080IJ	Diacylglycerol kinase
MADE_1010390	ENOG4105CBC	glutamate synthase
MADE_1010410	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
MADE_1010445	ENOG4105C59	p-type ATPase
MADE_1010460	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
MADE_1010465	ENOG4105Q9Y	Universal stress protein
MADE_1010470	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
MADE_1010475	ENOG4105D78	K07001 NTE family protein
MADE_1010500	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
MADE_1010505	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
MADE_1010510	ENOG4105KHC	sulfurtransferase
MADE_1010515	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
MADE_1010520	ENOG4106IUH	DTW domain containing protein
MADE_1010575	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
MADE_1010620	ENOG4105CHM	Aminotransferase
MADE_1010640	ENOG4108VGI	doxx family
MADE_1010645	ENOG4105CC0	LysR family Transcriptional regulator
MADE_1010675	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
MADE_1010690	ENOG4105D05	Receptor
MADE_1010695	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
MADE_1010700	ENOG4105WMR	Protein CrcB homolog
MADE_1010705	ENOG4105D1H	recombination factor protein RarA
MADE_1010710	ENOG4105DCF	alanine dehydrogenase
MADE_1010715	ENOG4105EW9	transcriptional regulator AsnC family
MADE_1010725	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
MADE_1010730	ENOG4105CFV	Tetratricopeptide repeat protein
MADE_1010765	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
MADE_1010770	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
MADE_1010775	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
MADE_1010780	ENOG4105XPH	Ferredoxin
MADE_1010800	ENOG4105BZU	Histidine kinase
MADE_1010810	ENOG4105C8V	SAICAR synthetase
MADE_1010815	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
MADE_1010835	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MADE_1010845	ENOG4105ERG	peptidase m48, ste24p
MADE_1010855	ENOG4105K89	arsenate reductase
MADE_1010860	ENOG4105CS1	NAD(P)H quinone oxidoreductase
MADE_1010870	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
MADE_1010880	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
MADE_1010885	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
MADE_1010895	ENOG4107QPN	acyl-Coa dehydrogenase
MADE_1010910	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
MADE_1010915	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
MADE_1010920	ENOG4105DBI	uridine monophosphokinase
MADE_1010925	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
MADE_1010930	ENOG4105C3Q	Glycosyl transferase, family 2
MADE_1010935	ENOG4107QW3	Sucrose phosphorylase
MADE_1010940	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
MADE_1010945	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
MADE_1010950	ENOG4107QI1	Mate efflux family protein
MADE_1010970	ENOG4105C6T	cysteine synthase
MADE_1011030	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
MADE_1011085	ENOG4105JAB	phenazine biosynthesis protein, phzf family
MADE_1011090	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
MADE_1011350	ENOG4105EN6	Membrane
MADE_1011475	ENOG4105IHM	Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity)
MADE_1011495	ENOG4105E5H	Transposase
MADE_1011500	ENOG4105EXC	Acyl-transferase
MADE_1011525	ENOG41082SX	arsR family transcriptional regulator
MADE_1011535	ENOG4105DUM	transcriptional regulator, lysR family
MADE_1011545	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
MADE_1011590	ENOG4105DK2	UPF0207 protein
MADE_1011615	ENOG4105VUT	cytoplasmic protein
MADE_1011630	ENOG4105BZG	amino acid carrier protein
MADE_1011650	ENOG4105E0X	reductase
MADE_1011655	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
MADE_1011665	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
MADE_1011670	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
MADE_1011675	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
MADE_1011680	ENOG4105DSB	aldose 1-epimerase
MADE_1011685	ENOG4108UHU	Aldolase
MADE_1011690	ENOG4105CHC	glucokinase (EC 2.7.1.2)
MADE_1011695	ENOG4105C01	Dihydroxy-acid dehydratase
MADE_1011700	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
MADE_1011705	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
MADE_1011710	ENOG4106KNT	transcriptional regulator
MADE_1011715	ENOG4105CA9	Pyruvate kinase
MADE_1011720	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
MADE_1011735	ENOG4105K3G	Periplasmic Protein
MADE_1011765	ENOG4105EIG	urea carboxylase-associated protein 1
MADE_1011780	ENOG4105BZU	Histidine kinase
MADE_1011800	ENOG4108K8S	endonuclease I
MADE_1011805	ENOG4105C8Q	Methyl-accepting chemotaxis
MADE_1011820	ENOG4108W5M	transcriptional regulator
MADE_1011825	ENOG4108I6A	alcohol dehydrogenase
MADE_1011830	ENOG4105BZU	Histidine kinase
MADE_1011840	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
MADE_1011845	ENOG4105BZU	Histidine kinase
MADE_1011885	ENOG4108S3P	Sporulation domain protein
MADE_1011890	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
MADE_1011895	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
MADE_1011915	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
MADE_1011920	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
MADE_1011925	ENOG4105MP9	class II Aldolase
MADE_1011940	ENOG4105YAJ	CopG Arc MetJ
MADE_1011950	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
MADE_1011955	ENOG4105CEY	Amp-dependent synthetase and ligase
MADE_1011970	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
MADE_1012005	ENOG4108Z6Z	Transcriptional regulator
MADE_1012010	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
MADE_1012035	ENOG4105DKW	ABC transporter
MADE_1012040	ENOG4105CRW	Short chain fatty acid transporter
MADE_1012045	ENOG4105BZU	Histidine kinase
MADE_1012070	ENOG4108BPE	-transporting atpase
MADE_1012100	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
MADE_1012135	ENOG4108UH6	UPF0754 membrane protein
MADE_1012155	ENOG4105CUG	Oligopeptidase b
MADE_1012160	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
MADE_1012165	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
MADE_1012170	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
MADE_1012175	ENOG4108428	Inherit from COG: -acetyltransferase
MADE_1012185	ENOG4108ZZ3	UPF0260 protein
MADE_1012190	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
MADE_1012200	ENOG4105VNG	YcgL domain-containing protein
MADE_1012205	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
MADE_1012210	ENOG4105CEY	Amp-dependent synthetase and ligase
MADE_1012215	ENOG410832A	alpha/beta hydrolase fold
MADE_1012230	ENOG41072GX	Peptidase M22 Glycoprotease
MADE_1012235	ENOG4105DVT	helicase
MADE_1012285	ENOG4105D05	Receptor
MADE_1012295	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
MADE_1012300	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
MADE_1012305	ENOG4105CIH	Imidazole acetol-phosphate transaminase
MADE_1012310	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
MADE_1012315	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
MADE_1012320	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
MADE_1012340	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
MADE_1012345	ENOG4105C34	Pseudouridine synthase
MADE_1012350	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MADE_1012360	ENOG4105K6V	RNA polymerase
MADE_1012375	ENOG4105EMU	Dehydrogenase
MADE_1012390	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
MADE_1012395	ENOG4106VK6	Flagellar motor protein
MADE_1012400	ENOG4105E14	MotA TolQ exbB proton channel
MADE_1012410	ENOG4105CTB	Polyprenyl synthetase
MADE_1012415	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
MADE_1012420	ENOG4108ZAI	phosphatidylglycerophosphatase a
MADE_1012425	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
MADE_1012430	ENOG4107YIM	Involved in the transcription termination process (By similarity)
MADE_1012435	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
MADE_1012450	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
MADE_1012455	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
MADE_1012460	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
MADE_1012465	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
MADE_1012470	ENOG4105C5H	ABC transporter
MADE_1012480	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
MADE_1012490	ENOG4105EAC	phosphoserine phosphatase
MADE_1012500	ENOG4105EYA	deoxyribonuclease
MADE_1012505	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
MADE_1012510	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
MADE_1012515	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
MADE_1012520	ENOG4105C3F	Signal peptidase i
MADE_1012525	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
MADE_1012545	ENOG4105EMN	RNA polymerase sigma factor
MADE_1012550	ENOG4108IYU	L-aspartate oxidase
MADE_1012565	ENOG4105Y75	tpr repeat protein
MADE_1012570	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
MADE_1012575	ENOG4108YZY	peptidylprolyl cis-trans isomerase
MADE_1012580	ENOG4108YZA	Nitrogen regulatory protein pii
MADE_1012585	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
MADE_1012645	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
MADE_1012650	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
MADE_1012655	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
MADE_1012670	ENOG4105DTN	riboflavin biosynthesis protein ribF
MADE_1012675	ENOG4105CJR	Integral membrane protein (MviN
MADE_1012680	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
MADE_1012695	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
MADE_1012700	ENOG4105C09	Bile acid
MADE_1012720	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
MADE_1012730	ENOG4105EIN	peptidylprolyl cis-trans isomerase
MADE_1012735	ENOG4105K70	DNA-binding protein
MADE_1012745	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
MADE_1012750	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
MADE_1012755	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
MADE_1012760	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
MADE_1012865	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MADE_1012870	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
MADE_1012875	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
MADE_1012885	ENOG4108Z4V	iron-sulfur cluster assembly
MADE_1012890	ENOG4105C9B	Cysteine desulfurase
MADE_1012895	ENOG4105JRK	feS assembly protein SufD
MADE_1012900	ENOG4105C3K	feS assembly ATPase SufC
MADE_1012910	ENOG4105C3J	Cysteine desulfurase
MADE_1012920	ENOG4105CT3	Monooxygenase
MADE_1012925	ENOG4105D7W	serine acetyltransferase
MADE_1012930	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
MADE_1012950	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
MADE_1012955	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
MADE_1012960	ENOG4105VIE	preprotein translocase, subunit YajC
MADE_1012970	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
MADE_1012985	ENOG4108P9J	Phage shock protein A
MADE_1013010	ENOG4106032	Glutathionylspermidine synthase
MADE_1013025	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
MADE_1013040	ENOG4105CSV	Glutaminase
MADE_1013045	ENOG4105G6Z	alkaline phosphatase
MADE_1013055	ENOG4107RET	Isocitrate lyase
MADE_1013170	ENOG4105CAQ	asparagine synthetase
MADE_1013190	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
MADE_1013225	ENOG4105S64	Formate nitrite transporter
MADE_1013230	ENOG4105C8Q	Methyl-accepting chemotaxis
MADE_1013250	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
MADE_1013255	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
MADE_1013260	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
MADE_1013270	ENOG4105BZU	Histidine kinase
MADE_1013275	ENOG4105BZU	Histidine kinase
MADE_1013280	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
MADE_1013285	ENOG4107QMP	dna polymerase iii subunits gamma and tau
MADE_1013290	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
MADE_1013300	ENOG4105E18	UPF0276 protein
MADE_1013330	ENOG4105EV9	Alpha Beta Hydrolase
MADE_1013340	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
MADE_1013345	ENOG4108NVR	Methyl-accepting chemotaxis
MADE_1013350	ENOG41090R7	Ferric uptake
MADE_1013365	ENOG4105P4J	Allophanate hydrolase, subunit 1
MADE_1013370	ENOG4105E7W	lamb ycsf family protein
MADE_1013375	ENOG4105QNR	S1 RNA binding domain protein
MADE_1013380	ENOG4108UKZ	OsmC family
MADE_1013385	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
MADE_1013410	ENOG4105CHM	Aminotransferase
MADE_1013415	ENOG4105DK2	UPF0207 protein
MADE_1013420	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
MADE_1013445	ENOG4105K5B	UPF0225 protein
MADE_1013460	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
MADE_1013470	ENOG4105C1G	acyl-Coa dehydrogenase
MADE_1013480	ENOG4107ZSV	Receptor
MADE_1013500	ENOG4105D4P	Coproporphyrinogen iii oxidase
MADE_1013505	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
MADE_1013510	ENOG4105E0C	molybdate abc transporter
MADE_1013520	ENOG4108ZAF	Molybdopterin
MADE_1013525	ENOG4105M00	molybdopterin converting factor, subunit 1
MADE_1013535	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
MADE_1013540	ENOG4105D06	uba thif-type nad fad binding protein
MADE_1013555	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
MADE_1013575	ENOG4105EG6	Saccharopine dehydrogenase
MADE_1013580	ENOG4105CIH	Imidazole acetol-phosphate transaminase
MADE_1013600	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
MADE_1013610	ENOG4107AQZ	Membrane
MADE_1013625	ENOG4107QYX	exodeoxyribonuclease v alpha
MADE_1013630	ENOG4107QKA	exodeoxyribonuclease V beta
MADE_1013635	ENOG4105DSY	exodeoxyribonuclease V, gamma
MADE_1013650	ENOG4108IQE	Amp-dependent synthetase and ligase
MADE_1013675	ENOG4105CVI	Transcriptional regulator
MADE_1013680	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
MADE_1013690	ENOG4105C28	cystathionine
MADE_1013705	ENOG4105CGF	Aromatic amino acid aminotransferase
MADE_1013715	ENOG4108UPT	UPF0178 protein
MADE_1013720	ENOG4105CHR	reductase
MADE_1013725	ENOG4105CHR	reductase
MADE_1013730	ENOG4105CSU	acyl-Coa dehydrogenase
MADE_1013735	ENOG4105FTV	AraC Family Transcriptional Regulator
MADE_1013760	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
MADE_1013770	ENOG4105C10	Electron transfer flavoprotein
MADE_1013775	ENOG4105BZJ	Electron transfer flavoprotein
MADE_1013780	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
MADE_1013785	ENOG4108YX2	DNA-binding protein
MADE_1013800	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
MADE_1013805	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
MADE_1013810	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
MADE_1013815	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
MADE_1013860	ENOG4105CMM	transposase
MADE_1013895	ENOG41061MV	Arylsulfatase
MADE_1013915	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
MADE_1013930	ENOG4108ZT0	50S ribosomal protein l17
MADE_1013935	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
MADE_1013940	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
MADE_1013945	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
MADE_1013950	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MADE_1013955	ENOG41067V7	50S ribosomal protein L36
MADE_1013960	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
MADE_1013965	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
MADE_1013970	ENOG4105VPB	50S ribosomal protein L30
MADE_1013975	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
MADE_1013980	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
MADE_1013985	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
MADE_1013990	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
MADE_1013995	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
MADE_1014000	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MADE_1014005	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
MADE_1014010	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
MADE_1014030	ENOG4105CSU	acyl-Coa dehydrogenase
MADE_1014060	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
MADE_1014065	ENOG4105E0F	Histidine kinase
MADE_1014075	ENOG4105NA0	Transcriptional regulator
MADE_1014100	ENOG4107XDR	Lactoylglutathione lyase
MADE_1014115	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
MADE_1014120	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
MADE_1014125	ENOG4105C7W	Xanthine dehydrogenase
MADE_1014145	ENOG4105CHR	reductase
MADE_1014150	ENOG4105EMU	Dehydrogenase
MADE_1014155	ENOG4107RKG	DJ-1/PfpI family
MADE_1014160	ENOG4107U9T	Pfam:Ribonuclease_BN
MADE_1014170	ENOG4108VWS	Yaeq family
MADE_1014200	ENOG4105S8Q	sugar efflux transporter
MADE_1014215	ENOG4105C9U	ATP-dependent DNA helicase RecQ
MADE_1014235	ENOG4105BZU	Histidine kinase
MADE_1014245	ENOG4105BZU	Histidine kinase
MADE_1014250	ENOG4105D8V	Glucose sorbosone dehydrogenase
MADE_1014265	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
MADE_1014270	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
MADE_1014275	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
MADE_1014280	ENOG4105CQM	Urea amidohydrolase subunit alpha
MADE_1014285	ENOG4105KI2	Urea amidohydrolase subunit beta
MADE_1014290	ENOG4108YZ9	Urea amidohydrolase subunit gamma
MADE_1014295	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
MADE_1014300	ENOG4108IV0	ABC, transporter
MADE_1014305	ENOG4105C0Z	ABC transporter
MADE_1014315	ENOG4105C32	Amino acid ABC transporter (Permease)
MADE_1014330	ENOG4105BZU	Histidine kinase
MADE_1014335	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
MADE_1014380	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
MADE_1014395	ENOG4108VWQ	crispr-associated protein
MADE_1014415	ENOG4105DTT	CRISPR-associated helicase, cas3
MADE_1014425	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MADE_1014430	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
MADE_1014435	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
MADE_1014440	ENOG4105CE4	GlcNAc 6-P deacetylase
MADE_1014445	ENOG4105RD7	BadF BadG BcrA BcrD
MADE_1014455	ENOG4105DAA	L-lactate
MADE_1014480	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
MADE_1014485	ENOG4105D0A	hydroxylase
MADE_1014490	ENOG4107RAQ	aminopeptidase
MADE_1014885	ENOG4107R08	Integrase
MADE_1014890	ENOG4108RVA	ribokinase
MADE_1014905	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
MADE_1014910	ENOG4105E66	phosphoriboisomerase A
MADE_1014915	ENOG4108JQ1	Dehydrogenase
MADE_1014935	ENOG4105XZD	Fe-S protein
MADE_1014970	ENOG4107QN2	dihydrolipoyl dehydrogenase
MADE_1014975	ENOG4107QSN	dihydrolipoamide acetyltransferase
MADE_1014980	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
MADE_1014985	ENOG41073TP	transcriptional regulator
MADE_1014995	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
MADE_1015000	ENOG4108WIW	Aspartyl protease
MADE_1015005	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
MADE_1015015	ENOG4105D7Q	type ii secretion system
MADE_1015020	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
MADE_1015040	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
MADE_1015045	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
MADE_1015050	ENOG4105C8Q	Methyl-accepting chemotaxis
MADE_1015055	ENOG4108ZXC	Two component transcriptional regulator, luxr family
MADE_1015060	ENOG4107QJE	Chromosome Partitioning Protein
MADE_1015070	ENOG4105CBS	Chea signal transduction histidine kinase
MADE_1015075	ENOG4108VYJ	response regulator receiver protein
MADE_1015080	ENOG4105BZU	Histidine kinase
MADE_1015090	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
MADE_1015095	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
MADE_1015100	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
MADE_1015105	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
MADE_1015110	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
MADE_1015115	ENOG4105DR5	peptidase
MADE_1015120	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
MADE_1015125	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
MADE_1015140	ENOG4105CPF	Cell wall formation (By similarity)
MADE_1015145	ENOG4105DFU	Cell wall formation (By similarity)
MADE_1015150	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
MADE_1015155	ENOG4105CNI	cell division protein FtsW
MADE_1015160	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
MADE_1015165	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
MADE_1015170	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
MADE_1015175	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
MADE_1015180	ENOG4105CJN	penicillin-binding protein
MADE_1015185	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
MADE_1015190	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
MADE_1015195	ENOG4108V6E	Cell division protein mraZ
MADE_1015250	ENOG4105EHV	domain protein
MADE_1015265	ENOG4105BZU	Histidine kinase
MADE_1015275	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
MADE_1015280	ENOG4105BZU	Histidine kinase
MADE_1015315	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
MADE_1015320	ENOG4105D7Z	glutathione synthase
MADE_1015325	ENOG4108UJU	UPF0301 protein
MADE_1015330	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
MADE_1015340	ENOG4105CZX	twitching motility protein
MADE_1015345	ENOG4105CZX	twitching motility protein
MADE_1015350	ENOG4105DFA	alanine racemase domain protein
MADE_1015355	ENOG4105II7	pyrroline-5-carboxylate reductase
MADE_1015360	ENOG4108VIA	integral membrane protein
MADE_1015370	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
MADE_1015385	ENOG4108SHQ	Glutathione S-transferase
MADE_1015390	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
MADE_1015395	ENOG4108Z9K	Osmotically inducible protein
MADE_1015400	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
MADE_1015415	ENOG4108UMN	azlc family
MADE_1015425	ENOG4105F27	Major Facilitator
MADE_1015430	ENOG4105VFU	Rna-binding protein
MADE_1015435	ENOG4105D1Q	UPF0246 protein
MADE_1015450	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
MADE_1015455	ENOG4107QP8	phosphohexose isomerase
MADE_1015465	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
MADE_1015470	ENOG4105D98	threonine synthase
MADE_1015475	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
MADE_1015490	ENOG4105CC0	LysR family Transcriptional regulator
MADE_1015505	ENOG41082YX	Transcriptional regulator, arsr family
MADE_1015515	ENOG4105CAU	Arsenical resistance protein, ArsH
MADE_1015520	ENOG4105D6J	arsenicaL-resistance protein
MADE_1015525	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
MADE_1015530	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
MADE_1015570	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
MADE_1015600	ENOG4105E3Q	saccharopine dehydrogenase
MADE_1015615	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
MADE_1015620	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
MADE_1015625	ENOG41082RQ	UPF0102 protein
MADE_1015635	ENOG4105CPK	Glycosyl transferase (Group 1
MADE_1015640	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
MADE_1015645	ENOG4105W4M	Transport-associated protein
MADE_1015665	ENOG4105BZU	Histidine kinase
MADE_1015695	ENOG4105CR4	methylisocitrate lyase
MADE_1015705	ENOG4105BZN	citrate synthase
MADE_1015710	ENOG4108I0Z	Aconitate hydratase
MADE_1015715	ENOG4105C7F	AcnD-accessory protein PrpF
MADE_1015720	ENOG4105BZU	Histidine kinase
MADE_1015740	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
MADE_1015745	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
MADE_1015770	ENOG4105BZU	Histidine kinase
MADE_1015775	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
MADE_1015790	ENOG4105BZ8	glutamate synthase
MADE_1015805	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
MADE_1015810	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
MADE_1015815	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
MADE_1015820	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
MADE_1015835	ENOG4105CJP	fad dependent oxidoreductase
MADE_1015840	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
MADE_1015850	ENOG4108K5P	(LipO)protein
MADE_1015855	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
MADE_1015860	ENOG4105EDR	glucose galactose transporter
MADE_1015870	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
MADE_1015890	ENOG4107MKT	Stringent starvation protein a
MADE_1015895	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
MADE_1015905	ENOG4105CSR	polyphosphate kinase 2
MADE_1015910	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
MADE_1015915	ENOG4107QMS	site-determining protein
MADE_1015920	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
MADE_1015925	ENOG4105C9Q	fumarate hydratase class II
MADE_1015960	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
MADE_1015965	ENOG4105CHM	Aminotransferase
MADE_1015975	ENOG4105CI3	gtp-binding protein typa
MADE_1015985	ENOG4105C5F	glutamine synthetase
MADE_1015995	ENOG4105CUX	Signal transduction histidine kinase
MADE_1016000	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
MADE_1016005	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
MADE_1016010	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
MADE_1016015	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
MADE_1016025	ENOG4105BZU	Histidine kinase
MADE_1016045	ENOG4105BZU	Histidine kinase
MADE_1016050	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
MADE_1016055	ENOG4105MYG	DNA polymerase iii, chi subunit
MADE_1016060	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
MADE_1016065	ENOG4108M8S	permease YjgP YjgQ family protein
MADE_1016070	ENOG4108K5H	permease YjgP YjgQ family protein
MADE_1016085	ENOG4105K6V	RNA polymerase
MADE_1016150	ENOG4105CK5	oxidoreductase
MADE_1016190	ENOG4105CA0	peroxidase
MADE_1016245	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
MADE_1016250	ENOG4105EHG	Permease protein
MADE_1016255	ENOG4107R4I	Periplasmic binding protein
MADE_1016265	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
MADE_1016275	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
MADE_1016280	ENOG4105EMK	carboxylate amino acid amine transporter
MADE_1016315	ENOG4105CY0	Metallo-Beta-Lactamase
MADE_1016330	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
MADE_1016355	ENOG4105BZU	Histidine kinase
MADE_1016360	ENOG4105JQN	Transcriptional regulator
MADE_1016365	ENOG4105C26	Dehydrogenase
MADE_1016370	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
MADE_1016375	ENOG4105C94	Transporter
MADE_1016380	ENOG4105CXG	d-lactate dehydrogenase
MADE_1016385	ENOG41086KC	Transcriptional regulator
MADE_1016390	ENOG4105P8Q	Curli production assembly transport component CsgG
MADE_1016420	ENOG4105WH1	Two component transcriptional regulator luxr family
MADE_1016435	ENOG4105C1J	atp-dependent rna helicase
MADE_1016445	ENOG4105BZU	Histidine kinase
MADE_1016460	ENOG4108UHU	Aldolase
MADE_1016465	ENOG4108RVA	ribokinase
MADE_1016510	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
MADE_1016525	ENOG4105DC8	reductase
MADE_1016540	ENOG4105BZ9	Cytochrome C oxidase, subunit I
MADE_1016545	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
MADE_1016570	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
MADE_1016590	ENOG4105EGS	Mechanosensitive ion channel
MADE_1016605	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
MADE_1016635	ENOG4105HF0	Membrane
MADE_1016640	ENOG4105CIH	Imidazole acetol-phosphate transaminase
MADE_1016655	ENOG4105BZU	Histidine kinase
MADE_1016665	ENOG4105CQ2	DNA polymerase
MADE_1016675	ENOG4105CEY	Amp-dependent synthetase and ligase
MADE_1016690	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
MADE_1016695	ENOG4105EJ2	Transcriptional regulator
MADE_1016705	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
MADE_1016715	ENOG4108RG0	uracil-dna glycosylase
MADE_1016720	ENOG4105BZU	Histidine kinase
MADE_1016730	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
MADE_1016735	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
MADE_1016760	ENOG4105FM1	phage shock protein C
MADE_1016765	ENOG41087YS	Phage shock protein A
MADE_1016775	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
MADE_1016790	ENOG4105E5H	Transposase
MADE_1016840	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
MADE_1016930	ENOG4105UYK	outer membrane protein a
MADE_1016935	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
MADE_1016940	ENOG4105BZU	Histidine kinase
MADE_1016945	ENOG4105C4W	S-formylglutathione hydrolase
MADE_1016950	ENOG4106HNH	Acyl-transferase
MADE_1016955	ENOG4106HNH	Acyl-transferase
MADE_1016960	ENOG4105CUY	Mechanosensitive ion channel
MADE_1016975	ENOG4108535	NAD dependent epimerase/dehydratase family
MADE_1016980	ENOG4105C8J	)-transporter
MADE_1016995	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
MADE_1017015	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
MADE_1017375	ENOG4108N3W	hemolysin secretion protein
MADE_1017380	ENOG4105D4A	Cell wall formation (By similarity)
MADE_1018005	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
MADE_1018015	ENOG4105C2N	RNA methyltransferase TrmH family group 3
MADE_1018020	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
MADE_1018065	ENOG4108UV7	flagellar protein motX
MADE_1018075	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
MADE_1018080	ENOG4107QK7	reductase
MADE_1018095	ENOG4107VAM	peptidase, m28
MADE_1018105	ENOG4105BZU	Histidine kinase
MADE_1018115	ENOG4105C4M	(Ubiquinol oxidase) subunit I
MADE_1018120	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
MADE_1018130	ENOG4108XM1	transcriptional regulator AsnC family
MADE_1018140	ENOG4105VEQ	Cold shock protein
MADE_1018145	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
MADE_1018165	ENOG4105DGW	oligopeptidase A
MADE_1018170	ENOG4107QQR	Sporulation
MADE_1018180	ENOG4105BZU	Histidine kinase
MADE_1018185	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
MADE_1018190	ENOG4105DC8	reductase
MADE_1018195	ENOG4107QY8	reductase
MADE_1018200	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
MADE_1018250	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
MADE_1018255	ENOG4108JJA	ABC, transporter
MADE_1018260	ENOG4105WH1	Two component transcriptional regulator luxr family
MADE_1018270	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
MADE_1018280	ENOG4108R8Z	these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression
MADE_1018285	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
MADE_1018290	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
MADE_1018295	ENOG41063M6	Cell Division Protein
MADE_1018300	ENOG4105C25	Primosomal protein n'
MADE_1018305	ENOG4105VFB	Binds the 23S rRNA (By similarity)
MADE_1018315	ENOG4105C6K	Malic enzyme
MADE_1018320	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
MADE_1018325	ENOG4105SYT	Methylenetetrahydrofolate reductase
MADE_1018330	ENOG4107S2Z	UPF0761 membrane protein
MADE_1018350	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
MADE_1018355	ENOG4105SUU	thioesterase domain
MADE_1018360	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
MADE_1018365	ENOG4105D58	Diguanylate phosphodiesterase
MADE_1018370	ENOG4105D58	Diguanylate phosphodiesterase
MADE_1018375	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
MADE_1018380	ENOG4105CAK	Cell division ATP-binding protein ftsE
MADE_1018385	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MADE_1018390	ENOG4106H78	methyltransferase
MADE_1018400	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
MADE_1018415	ENOG4105PW4	Sugar fermentation stimulation protein homolog
MADE_1018420	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MADE_1018425	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
MADE_1018430	ENOG4105DJ0	Poly(A) Polymerase
MADE_1018435	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MADE_1018440	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
MADE_1018445	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
MADE_1018450	ENOG4105DY8	decarboxylase
MADE_1018465	ENOG4105E3A	(ABC) transporter
MADE_1018470	ENOG4105DA5	(ABC) transporter
MADE_1018475	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
MADE_1018480	ENOG4105EB3	Histidine kinase
MADE_1018485	ENOG4108ESX	Receptor
MADE_1018490	ENOG4107E2E	PKHD-type hydroxylase
MADE_1018515	ENOG4105D22	carbon starvation protein
MADE_1018535	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
MADE_1018540	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
MADE_1018545	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
MADE_1018925	ENOG4108RPX	mosc domain containing protein
MADE_1018940	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
MADE_1018945	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
MADE_1018950	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
MADE_1018975	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
MADE_1018980	ENOG4105BZU	Histidine kinase
MADE_1018985	ENOG4107SDU	Methyl-accepting chemotaxis
MADE_1018995	ENOG4105PGM	cation diffusion facilitator family transporter
MADE_1019025	ENOG4105DFD	Na H antiporter
MADE_1019045	ENOG41060NJ	transcriptional regulator
MADE_1019055	ENOG4108JJ8	(ABC) transporter
MADE_1019060	ENOG4108JJ9	ABC, transporter
MADE_1019070	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
MADE_1019075	ENOG4105C4M	(Ubiquinol oxidase) subunit I
MADE_1019085	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
MADE_1019110	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
MADE_1019130	ENOG4105Q26	Siderophore-interacting protein
MADE_1019135	ENOG4105VDW	Csbd family
MADE_1019155	ENOG4108YZN	class I peptide chain release factor
MADE_1019180	ENOG4105DS1	cytochrome b561
MADE_1019215	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
MADE_1019220	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
MADE_1019230	ENOG4105BZU	Histidine kinase
MADE_1019255	ENOG41085KW	ppic-type peptidyL-prolyl cis-trans isomerase
MADE_1019260	ENOG41076YT	nitrate reductase, gamma subunit
MADE_1019265	ENOG4105R3A	Nitrate reductase
MADE_1019275	ENOG4105CRU	nitrate reductase, alpha subunit
MADE_1019280	ENOG4105BZU	Histidine kinase
MADE_1019285	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
MADE_1019290	ENOG4105E0C	molybdate abc transporter
MADE_1019295	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
MADE_1019305	ENOG4105WH1	Two component transcriptional regulator luxr family
MADE_1019310	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
MADE_1019325	ENOG4108ZAF	Molybdopterin
MADE_1019330	ENOG4105M00	molybdopterin converting factor, subunit 1
MADE_1019345	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
MADE_1019350	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
MADE_1019360	ENOG4105D06	uba thif-type nad fad binding protein
MADE_1019365	ENOG4105XPQ	lipid carrier protein
MADE_1019370	ENOG4105CFN	oxalyl-CoA decarboxylase
MADE_1019375	ENOG4105CFP	Peptidase U32
MADE_1019380	ENOG4106RZ4	Peptidase U32
MADE_1019395	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
MADE_1019400	ENOG4108JUA	Transcriptional regulator
MADE_1019405	ENOG4108YY7	Invasion gene expression up-regulator SirB
MADE_1019420	ENOG4107R3J	Transporter
MADE_1019425	ENOG4108QVN	serine threonine protein kinase
MADE_1019435	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
MADE_1019455	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
MADE_1019460	ENOG4105E98	transcriptional regulator DeoR family
MADE_1019465	ENOG4105D9R	oxidoreductase
MADE_1019470	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
MADE_1019480	ENOG4108Q5Y	Membrane
MADE_1019485	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
MADE_1019495	ENOG41066YJ	Beta-lactamase
MADE_1019500	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
MADE_1019510	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
MADE_1019515	ENOG4105W8H	transhydrogenase (subunit alpha
MADE_1019520	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
MADE_1019565	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
MADE_1019570	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
MADE_1019575	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
MADE_1019580	ENOG4105CCU	oxidase (Subunit III)
MADE_1019585	ENOG4105BZ9	Cytochrome C oxidase, subunit I
MADE_1019590	ENOG4105E2S	oxidase) subunit II
MADE_1019625	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
MADE_1019630	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
MADE_1019635	ENOG4105FS0	cytoplasmic membrane protein
MADE_1019640	ENOG4105VF7	tolerance protein
MADE_1019645	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
MADE_1019650	ENOG4105DR5	peptidase
MADE_1019655	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
MADE_1019660	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
MADE_1019665	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
MADE_1019715	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
MADE_1019725	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
MADE_1019730	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
MADE_1019735	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
MADE_1019765	ENOG4105EYW	Ion transport protein
MADE_1019770	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
MADE_1019780	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
MADE_1019790	ENOG4105E0F	Histidine kinase
MADE_1019800	ENOG4105CJQ	hydrolase, family 31
MADE_1019805	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
MADE_1019810	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
MADE_1019830	ENOG4107QHF	type ii secretion system protein e
MADE_1019835	ENOG4105D7Q	type ii secretion system
MADE_1019840	ENOG4108VAU	general secretion pathway protein G
MADE_1019845	ENOG4105VWV	general secretion pathway protein h
MADE_1019885	ENOG4105C26	Dehydrogenase
MADE_1019895	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
MADE_1019915	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
MADE_1019930	ENOG4105YP7	UPF0270 protein
MADE_1019935	ENOG4105DNZ	Alpha Beta Hydrolase
MADE_1019965	ENOG41069P5	Protein slyX homolog
MADE_1019975	ENOG4108V1T	peptidylprolyl cis-trans isomerase
MADE_1019985	ENOG4108RRZ	Transcription elongation factor GreB
MADE_1020010	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
MADE_1020015	ENOG4105MJ2	Competence protein
MADE_1020025	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
MADE_1020050	ENOG4107BJW	polysaccharide deacetylase
MADE_1020060	ENOG4108ZX6	Electron transport protein SCO1 SenC
MADE_1020065	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
MADE_1020070	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
MADE_1020095	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
MADE_1020100	ENOG4105BZ9	Cytochrome C oxidase, subunit I
MADE_1020110	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
MADE_1020125	ENOG4105C01	Dihydroxy-acid dehydratase
MADE_1020140	ENOG4105EMY	transcriptional regulator
MADE_1020145	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
MADE_1020150	ENOG4105C2C	drug resistance transporter, Bcr CflA
MADE_1020160	ENOG4105CFU	surface antigen
MADE_1020165	ENOG4105MA0	exported protein
MADE_1020190	ENOG4105C5I	Dehydrogenase
MADE_1020200	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
MADE_1020245	ENOG4105CI2	imidazolone-5-propionate hydrolase
MADE_1020270	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
MADE_1020275	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
MADE_1020280	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
MADE_1020290	ENOG4105DSJ	YicC domain protein
MADE_1020395	ENOG4107R3N	Filamentation induced by cAMP protein fic
MADE_1020405	ENOG41060NJ	transcriptional regulator
MADE_1020415	ENOG4105CDV	Ompa motb domain protein
MADE_1020420	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
MADE_1020435	ENOG4108K3A	Glutathione S-transferase
MADE_1020445	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
MADE_1020450	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
MADE_1020455	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
MADE_1020460	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
MADE_1020475	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
MADE_1020480	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
MADE_1020485	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
MADE_1020495	ENOG4105FA0	parb-like partition protein
MADE_1020500	ENOG4107QJE	Chromosome Partitioning Protein
MADE_1020505	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
MADE_1020510	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
MADE_1020525	ENOG4105QTB	Flavodoxin
MADE_1020530	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
MADE_1020535	ENOG4108VPT	UPF0234 protein
MADE_1020550	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)